STOCK OPTION AGREEMENT
                            [Director Non-Qualified]


                  AGREEMENT made as of the 8th day of July 1999, by and between
KIRLIN HOLDING CORP., a Delaware corporation (the "Company"), and Harold Paul
(the "Director").

                  WHEREAS, on July 8, 1999 (the "Grant Date"), pursuant to the
terms and conditions of the Kirlin Holding Corp. 1996 Stock Plan (the "Plan"),
the Board of Directors of the Company authorized the grant to the Director of an
option (the "Option") to purchase an aggregate of 2,500 shares of the authorized
but unissued Common Stock of the Company, $.0001 par value (the "Common Stock"),
conditioned upon the Director's acceptance thereof upon the terms and conditions
set forth in this Agreement and subject to the terms of the Plan; and

                  WHEREAS, the Director desires to acquire the Option on the
terms and conditions set forth in this Agreement and subject to the terms of the
Plan;

                  IT IS AGREED:

                  1. Grant of Stock Option. The Company hereby grants the
Director the Option to purchase all or any part of an aggregate of 2,500 shares
of Common Stock (the "Option Shares") on the terms and conditions set forth
herein and subject to the provisions of the Plan.

                  2. Non-Incentive Stock Option. The Option represented hereby
is not intended to be an Option which qualifies as an "Incentive Stock Option"
under Section 422 of the Internal Revenue Code of 1986, as amended.

                  3. Exercise Price. The exercise price of the Option shall be
$13.625 per share, subject to adjustment as hereinafter provided.

                  4. Exercisability. This Option is exercisable, subject to the
terms and conditions of the Plan, immediately. It shall remain exercisable
except as otherwise provided herein, until the close of business on July 7, 2009
(the "Exercise Period").

                  5. Termination of Directorship. The Option shall terminate on
the third anniversary of the first date upon which the Director shall no longer
be a member of the Board of Directors of the Company, or any successor company,
for any reason whatsoever.

                  6. Withholding Tax. Not later than the date as of which an
amount first becomes includible in the gross income of the Director for Federal
income tax purposes with respect to the Option, the Director shall pay to the
Company, or make arrangements satisfactory to the Committee regarding the
payment of, any Federal, state and local taxes of any kind required by law to be
withheld or paid with respect to such amount. The obligations of the Company
under the Plan and pursuant to this Agreement shall be conditional upon such
payment or arrangements with the Company and the Company shall, to the extent
permitted by law, have the right to deduct any such taxes from any payment of
any kind otherwise due to the Director from the Company.

                  7. Adjustments. In the event of any merger, reorganization,
consolidation, recapitalization, consolidation, recapitalization, dividend
(other than cash dividend), stock split, reverse stock split, or other change in
corporate structure affecting the number of issued shares of Common Stock, the
Company shall proportionally adjust the number and kind of Option Shares


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and the exercise price of the Option in order to prevent the dilution or
enlargement of the Director's proportionate interest in the Company and her
rights hereunder, provided that the number of Option Shares shall always be a
whole number.

                  8.       Method of Exercise.

                           8.1.     Notice to the Company.  The Option shall be
exercised in whole or in part by written notice in substantially the form
attached hereto as Exhibit A directed to the Company at its principal place of
business accompanied by full payment as hereinafter provided of the exercise
price for the number of Option Shares specified in the notice.

                           8.2.     Delivery of Option Shares.  The Company
shall deliver a certificate for the Option Shares to the Director as soon as
practicable after payment therefor.

                           8.3.     Payment of Purchase Price.

                                    8.3.1.  Cash Payment.  The Director shall
make cash payments by wire transfer, certified or bank check or personal check,
in each case payable to the order of the Company; the Company shall not be
required to deliver certificates for Option Shares until the Company has
confirmed the receipt of good and available funds in payment of the purchase
price thereof.

                                    8.3.2.  Cashless Payment.  Provided that
prior approval of the Company has been obtained, the Director may use Common
Stock of the Company owned by him or her to pay the purchase price for the
Option Shares by delivery of stock certificates in negotiable form which are
effective to transfer good and valid title thereto to the Company, free of any
liens or encumbrances. Shares of Common Stock used for this purpose shall be
valued at the Fair Market Value.

                                    8.3.3.  Payment Price of Withholding Tax.
Any required withholding tax may be paid in cash or with Common Stock in
accordance with Sections 8.3.1. and 8.3.2.

                                    8.3.4.  Exchange Act Compliance.
Notwithstanding the foregoing, the Company shall have the right to reject
payment in the form of Common Stock if in the opinion of counsel for the
Company, (i) it could result in an event of "recapture" under Section 16(b) of
the Securities Exchange Act of 1934; (ii) such shares of Common Stock may not be
sold or transferred to the Company; or (iii) such transfer could create legal
difficulties for the Company.

                  9. Nonassignability. The Option shall not be assignable or
transferable except by will or by the laws of descent and distribution in the
event of the death of the Director. No transfer of the Option by the Director by
will or by the laws of descent and distribution shall be effective to bind the
Company unless the Company shall have been furnished with written notice thereof
and a copy of the will and such other evidence as the Company may deem necessary
to establish the validity of the transfer and the acceptance by the transferee
or transferees of the terms and conditions of the Option.

                  10. Company Representations. The Company hereby represents and
warrants to the Director that:



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                           (i) the Company, by appropriate and all required
         action, is duly authorized to enter into this Agreement and consummate
         all of the transactions contemplated hereunder; and

                           (ii) the Option Shares, when issued and delivered by
         the Company to the Director in accordance with the terms and conditions
         hereof, will be duly and validly issued and fully paid and
         non-assessable.

                  11.      Director Representations.  The Director hereby
represents and warrants to the Company that

                           (i)      he or she is acquiring the Option and shall
         acquire the Option Shares for his or her own account and not with a
         view towards the distribution thereof;

                           (ii) he or she has received a copy of all reports and
         documents required to be filed by the Company with the Commission
         pursuant to the Exchange Act within the last 24 months and all reports
         issued by the Company to its stockholders;

                           (iii) he or she understands that he or she must bear
         the economic risk of the investment in the Option Shares, which cannot
         be sold by his or her unless they are registered under the Securities
         Act of 1933 (the "1933 Act") or an exemption therefrom is available
         thereunder and that the Company is under no obligation to register the
         Option Shares for sale under the 1933 Act;

                           (iv) in his or her position with the Company, he or
         she has had both the opportunity to ask questions and receive answers
         from the officers and directors of the Company and all persons acting
         on its behalf concerning the terms and conditions of the offer made
         hereunder and to obtain any additional information to the extent the
         Company possesses or may possess such information or can acquire it
         without unreasonable effort or expense necessary to verify the accuracy
         of the information obtained pursuant to clause (ii) above;

                           (v) he or she is aware that the Company shall place
         stop transfer orders with its transfer agent against the transfer of
         the Option Shares in the absence of registration under the 1933 Act or
         an exemption therefrom as provided herein; and

                           (vi) in the absence of registration under the 1933
         Act, the certificates evidencing the Option Shares shall bear the
         following legend:

                           "The shares represented by this certificate have been
                           acquired for investment and have not been registered
                           under the Securities Act of 1933. The shares may not
                           be sold or transferred in the absence of such
                           registration or an exemption therefrom under said
                           Act."

                  12. Restriction on Transfer of Option Shares. Anything in this
Agreement to the contrary notwithstanding, the Director hereby agrees that he or
she shall not sell, transfer by any means or otherwise dispose of the Option
Shares acquired by him or her without registration under the 1933 Act, or in the
event that they are not so registered, unless (i) an exemption from the 1933 Act
registration requirements is available thereunder, and (ii) the Director has



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furnished the Company with notice of such proposed transfer and the Company's
legal counsel, in its reasonable opinion, shall deem such proposed transfer to
be so exempt.

                  13.      Miscellaneous.

                           13.1.    Notices.  All notices, requests, deliveries,
payments, demands and other communications which are required or permitted to be
given under this Agreement shall be in writing and shall be either delivered
personally or sent by registered or certified mail, or by private courier,
return receipt requested, postage prepaid to the Company at its principal
executive office and to the Director at his address set forth below, or to such
other address as either party shall have specified by notice in writing to the
other. Notice shall be deemed duly given hereunder when delivered or mailed as
provided herein.

                           13.2.    Plan Paramount; Conflicts with Plan.  This
Agreement and the Option shall, in all respects, be subject to the terms and
conditions of the Plan, whether or not stated herein. In the event of a conflict
between the provisions of the Plan and the provisions of this Agreement, the
provisions of the Plan shall in all respects be controlling.

                           13.3.    Stockholder Rights.  The Director shall not
have any of the rights of a stockholder with respect to the Option Shares until
such shares have been issued after the due exercise of the Option.

                           13.4.    Waiver.  The waiver by any party hereto of
a breach of any provision of this Agreement shall not operate or be construed as
a waiver of any other or subsequent breach.

                           13.5.    Entire Agreement.  This Agreement
constitutes the entire agreement between the parties with respect to the subject
matter hereof. This Agreement may not be amended except by writing executed by
the Director and the Company.

                           13.6.    Binding Effect; Successors.  This Agreement
shall inure to the benefit of and be binding upon the parties hereto and, to the
extent not prohibited herein, their respective heirs, successors, assigns and
representatives. Nothing in this Agreement, expressed or implied, is intended to
confer on any person other than the parties hereto and as provided above, their
respective heirs, successors, assigns and representatives any rights, remedies,
obligations or liabilities.

                           13.7.    Governing Law.  This Agreement shall be
governed by and construed in accordance with the laws of the State of New York
(without regard to choice of law provisions).

                           13.8.    Headings.  The headings contained herein are
for the sole purpose of convenience of reference, and shall not in any way limit
or affect the meaning or interpretation of any of the terms or provisions of
this Agreement.



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                  IN WITNESS WHEREOF, the parties hereto have signed this
Agreement as of the day and year first above written.

DIRECTOR :                                      KIRLIN HOLDING CORP.

/s/ Harold Paul                                 /s/ Anthony J. Kirincic
--------------------                        By: ------------------------------
Harold Paul                                     Anthony J. Kirincic, President



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                                                                     EXHIBIT A

                      FORM OF NOTICE OF EXERCISE OF OPTION


-----------------------------------
                  DATE


Kirlin Holding Corp.

Attention:  Board of Directors

                  Re:      Purchase of Option Shares

Gentlemen:

     In accordance with my Stock Option Agreement dated as of July 8, 1999
("Agreement") with Kirlin Holding Corp. (the "Company"), I hereby irrevocably
elect to exercise the right to purchase _________ shares of the Company's common
stock, par value $.0001 per share ("Common Stock"), which are being purchased
for investment and not for resale.

     As payment for my shares, enclosed is (check and complete applicable
box[es]):

     |_|  a [personal check] [certified check] [bank check] payable to the order
          of "Kirlin Holding Corp." in the sum of $_________;

     |_|  confirmation of wire transfer in the amount of $_____________; and/or

     |_|  [If prior approval of the Company has been obtained,] certificate for
          ____ shares of the Company's Common Stock, free and clear of any
          encumbrances, duly endorsed, having a Fair Market Value (as such term
          is defined in the Company's 1996 Stock Plan) of $_________.

     I hereby represent, warrant to, and agree with, the Company that

          (i) I am acquiring the Option Shares for my own account and not with
a view towards the distribution thereof;

          (ii) I have received a copy of all reports and documents required to
be filed by the Company with the Commission pursuant to the Exchange Act within
the last 24 months and all reports issued by the Company to its stockholders;

          (iii) I understand that I must bear the economic risk of the
investment in the Option Shares, which cannot be sold by me unless they are
registered under the Securities Act of 1933 (the "1933 Act") or an exemption
therefrom is available thereunder and that the Company is under no obli gation
to register the Option Shares for sale under the 1933 Act;

          (iv) in my position with the Company, I have had both the opportunity
to ask questions and receive answers from the officers and directors of the
Company and all persons acting on its behalf concerning the terms and conditions




<PAGE>

of the offer made hereunder and to obtain any additional information to the
extent the Company possesses or may possess such information or can acquire it
without unreasonable effort or expense necessary to verify the accuracy of the
information obtained pursuant to clause (ii) above;

          (v) I am aware that the Company shall place stop transfer orders with
its transfer agent against the transfer of the Option Shares in the absence of
registration under the 1933 Act or an exemption therefrom as provided herein;

          (vi) my rights with respect to the Option Shares shall, in all
respects, be subject to the terms and conditions of this Company's 1996 Stock
Plan and this Agreement; and

          (vii) in the absence of registration under the 1933 Act, the
certificates evidencing the Option Shares shall bear the following legend:

               "The shares represented by this certificate have been acquired
               for investment and have not been registered under the Securities
               Act of 1933. The shares may not be sold or transferred in the
               absence of such registration or an exemption therefrom under said
               Act."

Kindly forward to me my certificate at your earliest convenience.

Very truly yours,


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(Signature)                                (Address)

----------------------------------         -------------------------------------
(Print Name)                               (Address)

                                           -------------------------------------
                                           (Social Security Number)


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