53676 Federal Register / Vol. 70, No. 174 / Friday, September 9, 2005 / Notices 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Library of Medicine; 

Cancellation of Meetings 

Notice is hereby given of the 

cancellation of the Commission on 

Systemic Interoperability, September 

13, 2005, 8 a.m. to 4 p.m., Hubert H. 

Humphrey Building, Room 800, 200 

Independence Avenue, Washington, DC 

20201, cancellation of the Commission 

on Systemic Interoperability 

Teleconference, October 11, 2005, 

3 p.m. to 4:30 p.m., National Library of 

Medicine, Conference Room B, Building 

38, 2nd Floor, Bethesda, Maryland 

20894, and the cancellation of the 

Commission on Systemic 

Interoperability, October 24, 2005, 

8 a.m. to 1 p.m., Hubert H. Humphrey 

Building, Room 800, 200 Independence 

Avenue, Washington, DC 20201, all of 

which were published in the Federal 

Register on July 13, 2005, 70 FR 40392. 

These meetings are cancelled, as they 

are no longer necessary to complete 

Commission activities. 

Dated: August 31, 2005. 

Anthony M. Coelho, Jr., 

Acting Director, Office of Federal Advisory 

Committee Policy. 

[FR Doc. 05–17940 Filed 9–8–05; 8:45 am] 

BILLING CODE 4140–01–M 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

National Institutes of Health 

National Toxicology Program (NTP); 

NTP Interagency Center for the 

Evaluation of Alternative Toxicological 

Methods (NICEATM); Announcement 

of Expert Panel Meeting To Evaluate 

Revised Analyses and Proposed 

Reference Substances for In Vitro Test 

Methods for Identifying Ocular 

Corrosives and Severe Irritants 

AGENCY: National Institute of 

Environmental Health Sciences 

(NIEHS), National Institutes of Health 

(NIH), Department of Health and Human 

Services (HHS). 

ACTION: Meeting announcement and 

opportunity for public comment. 

SUMMARY: NICEATM announces a 

second meeting of an expert panel by 

teleconference on September 19, 2005, 

to evaluate (1) revised accuracy and 

reliability analyses of four in vitro test 

methods proposed for detecting ocular 

corrosives and severe irritants and (2) a 

revised list of proposed reference 

substances for validation studies on in 

vitro test methods for identifying ocular 

corrosives and severe irritants. The four 

in vitro test methods under 

consideration are the (1) Bovine Corneal 

Opacity and Permeability (BCOP) assay, 

(2) Hen’s Egg Test—Chorion Allantoic 

Membrane (HET–CAM), (3) Isolated 

Rabbit Eye (IRE) assay, and (4) Isolated 

Chicken Eye (ICE) assay. The revised 

analyses and revised list of proposed 

reference substances are available in an 

addendum to the draft Background 

Review Documents (BRDs) for the four 

methods (available at http:// 

iccvam.niehs.nih.gov/methods/ocudocs/ 

reanalysis.htm). A previous Federal 

Register notice solicited public 

comment on the revised analyses and 

revised list of proposed reference 

substances (Vol. 70, No. 142, pg. 43149, 

July 26, 2005). Comments submitted in 

response to the July 26, 2005 Federal 

Register notice will be considered at the 

expert panel meeting and do not need 

to be resubmitted. The public is invited 

to attend the teleconference and will be 

provided with an opportunity to make 

oral comments during the public 

comment period. Interested individuals 

can attend the meeting via a phone line 

or in person at the NIEHS campus (see 

ADDRESSES below). Participation is 

limited only by the number of phone 

lines available and by the number of 

available seats at the teleconference site. 

Additional meeting information may be 

obtained on the ICCVAM/NICEATM 

Web site (http://iccvam.niehs.nih.gov) 

or by contacting NICEATM (see 

ADDRESSES below). 

DATES: The expert panel meeting will be 

held via teleconference on Monday, 

September 19, 2005, beginning at 9 a.m. 

eastern daylight time (e.d.t.) and 

continuing until adjournment 

(approximately 12 p.m. e.d.t.). 

Requests to attend the meeting via the 

telephone or in person must be received 

no later than September 12, 2005, to 

ensure access (see ADDRESSES below). 

We encourage all individuals who plan 

to attend this meeting to register online 

at the NICEATM Web site (http:// 

iccvam.niehs.nih.gov/), but requests 

may also be submitted by e-mail, 

telephone, fax, or through hand 

delivery/courier (see ADDRESSES below). 

Persons wishing to make oral 

comments during the teleconference 

must notify NICEATM no later than 

September 12, 2005 (see ADDRESSES

below). In lieu of oral comments, 

individuals may provide written 

comments for distribution to the expert 

panel prior to the meeting. Written 

comments should be received by 

September 15, 2005, in order to enable 

consideration by the expert panel prior 

to the meeting. 

Persons with disabilities, such as 

those who need sign language 

interpreters and/or other reasonable 

accommodation to participate in this 

meeting at NIEHS, are asked to notify 

NICEATM by September 8, 2005. 

ADDRESSES: The teleconference will 

originate from Room 3162, 3rd Floor, 

NIEHS, 79 T.W. Alexander Drive, Bldg. 

4401, Research Triangle Park, NC. A 

government-approved photo ID is 

required to access the meeting. 

Correspondence should be sent by 

mail, fax, e-mail, or through hand 

delivery/courier to Dr. Raymond Tice at 

NICEATM, NIEHS, PO Box 12233, MD 

EC–17, Research Triangle Park, NC 

27709, (phone) 919–541–4482, (fax) 

919–541–0947, (e-mail) 

niceatmcomments@niehs.nih.gov. 

Courier address: NICEATM, 79 T.W. 

Alexander Drive, Building 4401, Room 

3129, Research Triangle Park, NC 27709. 

SUPPLEMENTARY INFORMATION: 

Background 

On November 3, 2004, NICEATM 

released draft BRDs that provided 

information about the current validation 

status of the four in vitro test methods 

for detecting ocular corrosives and 

severe irritants (Federal Register, Vol. 

69, No. 212, pp. 64081–64082, 

November 3, 2004). In conjunction with 

ICCVAM, NICEATM convened an 

expert panel meeting on January 11–12, 

2005, to independently assess the 

validation status of the four in vitro test 

methods. The expert panel report and 

background information for this meeting 

are available at http:// 

iccvam.niehs.nih.gov/methods/ 

eyeirrit.htm. Public comments at the 

meeting indicated that additional data 

could be made available that had not 

been provided in response to earlier 

requests for data announced in the 

Federal Register in March (Vol. 69, No. 

57, pp. 13859–13861, March 24, 2004) 

and November 2004). The expert panel 

recommended that NICEATM conduct a 

reanalysis of the accuracy and reliability 

of each test method that would include 

these data. In response to this 

recommendation, NICEATM published 

a notice in the Federal Register (Vol. 70, 

No. 38, pp. 9661–9662, February 28, 

2005) requesting additional in vitro data 

on these four in vitro ocular irritancy 

test methods, corresponding in vivo 

rabbit eye test method data, as well as 

any human ocular exposure/injury data 

(either from ethical human studies or 

accidental exposure). Subsequently, 

NICEATM received additional in vitro 

and in vivo data that were used for the 

Federal Register / Vol. 70, No. 174 / Friday, September 9, 2005 / Notices 53677 

revised accuracy and reliability analyses 

and considered in revising the list of 

proposed reference substances. 

In preparation for this teleconference, 

NICEATM released the revised accuracy 

and reliability analyses and the revised 

list of proposed reference substances as 

an addendum to the draft BRDs and 

announced its availability in the July 26, 

2006 Federal Register notice. Following 

the expert panel teleconference, a 

second expert panel report will be 

published and made available for public 

comment. ICCVAM will consider both 

expert panel reports, other relevant 

background materials, and all comments 

received from the public and the 

Scientific Advisory Committee on 

Alternative Toxicological Methods 

(SACATM) on this topic in finalizing 

ICCVAM recommendations for these 

test methods. 

Opportunity for Public Comment 

Public comments may be made on the 

revised accuracy and reliability analyses 

for BCOP, HET–CAM, ICE, and IRE and 

on the proposed list of reference 

substances. In lieu of oral comments, 

individuals may provide written 

comments for distribution to the expert 

panel prior to the meeting. Written 

comments should be received no later 

than September 15, 2005, to enable 

consideration by the expert panel prior 

to the meeting. Written comments 

received in response to the July 26, 2005 

Federal Register notice announcing 

availability of the addendum to the draft 

BRDs do not need to be resubmitted. If 

written comments are submitted, 

appropriate contact information (name, 

affiliation, mailing address, phone, fax, 

email and sponsoring organization, if 

applicable) should be included. Written 

comments will be posted on the 

NICEATM/ICCVAM Web site and made 

available to the expert panel and the 

ICCVAM. Persons wishing to make oral 

comments during the teleconference 

(one speaker per organization) must 

notify NICEATM by no later than 

September 12, 2005. Speakers will be 

assigned on a consecutive basis and 

comments will be limited to no more 

than four minutes per speaker. Due to 

logistical issues it may not be possible 

for persons who do not pre-register to 

make oral comments. 

Background Information on ICCVAM 

and NICEATM 

ICCVAM is an interagency committee 

composed of representatives from 15 

Federal regulatory and research agencies 

that use or generate toxicological 

information. ICCVAM conducts 

technical evaluations of new, revised, 

and alternative methods with regulatory 

applicability, and promotes the 

scientific validation and regulatory 

acceptance of toxicological test methods 

that more accurately assess the safety 

and hazards of chemicals and products 

and that refine, reduce, and replace 

animal use. The ICCVAM Authorization 

Act of 2000 (Pub. L. 106–545, available 

at http://iccvam.niehs.nih.gov/about/ 

PL106545.htm) establishes ICCVAM as a 

permanent interagency committee of the 

NIEHS under the NICEATM. NICEATM 

administers the ICCVAM and provides 

scientific and operational support for 

ICCVAM-related activities. NICEATM 

and ICCVAM work collaboratively to 

evaluate new and improved test 

methods applicable to the needs of 

Federal agencies. Additional 

information about ICCVAM and 

NICEATM can be found at the following 

Web site: http:// 

www.iccvam.niehs.nih.gov. 

Dated: August 30, 2005. 

Samuel H. Wilson, 

Deputy Director, National Institute of 

Environmental Health Sciences. 

[FR Doc. 05–17939 Filed 9–8–05; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

Coast Guard 

[CGD13–05–017] 

Letter of Recommendation, Proposed 

LNG Project Northern Star Natural Gas 

LLC, Bradwood, Clatsop County, OR 

AGENCY: Coast Guard, DHS. 

ACTION: Request for comments; notice of 

public meeting. 

SUMMARY: In accordance with the 

requirements in 33 CFR 127.009, the 

U.S. Coast Guard Captain of the Port 

(COTP) Portland, Oregon is preparing a 

Letter of Recommendation (LOR) as to 

the suitability of the Columbia River for 

liquefied natural gas (LNG) marine 

traffic. This LOR will encompass the 

marine safety and security aspects 

associated with the proposed Northern 

Star Natural Gas LLC (Northern Star) 

LNG facility. The LOR is in response to 

a Letter of Intent (LOI) submitted by 

Northern Star to operate an LNG facility 

in Bradwood, Clatsop County, Oregon. 

Because the proposed LNG facility 

would be located in state waters, the 

Federal Energy Regulatory Commission 

(FERC) is the lead Federal agency for 

this proposed project. The COTP 

Portland, OR is soliciting written 

comments and related material, and will 

join FERC in holding a public meeting 

seeking comments, pertaining 

specifically to maritime safety and 

security aspects of the proposed LNG 

facility. In preparation for issuance of an 

LOR and the completion of certain other 

regulatory mandates, the COTP 

Portland, OR, will consider comments 

received from the public as input into 

a formalized risk assessment process. 

This process will assess the safety and 

security aspects of the facility, adjacent 

port areas, and navigable waterways. 

DATES: All written comments and 

related material must reach the Coast 

Guard on or before October 6, 2005. In 

addition, a public meeting will be held 

Thursday, September 29, 2005 at 7 p.m. 

Those who plan to speak at the meeting 

should provide their name by 

September 22, 2005 to Lieutenant 

Shadrack Scheirman using one of the 

methods listed under FOR FURTHER

INFORMATION CONTACT. The comment 

period associated with the public 

meeting will remain open for seven days 

following the meeting. The meeting 

location is: Knappa High School, 41535 

Old Highway 30, Astoria, OR 97102, 

503–458–6166. 

ADDRESSES: You may submit written 

comments to Commanding Officer, U.S. 

Coast Guard Sector Portland. Sector 

Portland maintains a file for this notice. 

Comments and material received will 

become part of this file and will be 

available for inspection and copying at 

Sector Portland between 8 a.m. and 3 

p.m. Monday through Friday, except 

Federal holidays. 

FOR FURTHER INFORMATION CONTACT: If 

you have questions on this notice, 

contact Lieutenant Shadrack Scheirman 

at Sector Portland by one of the methods 

listed below: 

(1) Phone at (503) 247–4015 

(2) E-mail at 

Shadrack.L.Scheirman@uscg.mil 

(3) Fax to (503) 240–2586 

SUPPLEMENTARY INFORMATION: 

Request for Written Comments 

We encourage you to submit written 

comments and related material 

pertaining specifically to marine safety 

and security aspects associated with the 

proposed Northern Star LNG facility. If 

you do so, please include your name 

and address, identify the docket number 

for this notice ([CGD13–05–017]), and 

give the reason for each comment. You 

may submit your comments and related 

material by mail, or hand delivery, as 

described in ADDRESSES, or you may 

send them by fax or e-mail using the 

contact information under FOR FURTHER

INFORMATION CONTACT. To avoid 

confusion and duplication, please