Exhibit 10.1




  FORM OF SUBSCRIPTION AGREEMENT


  Genta Incorporated

Two Connell Drive

Berkeley Heights, New Jersey 07922


  Ladies and Gentlemen:


     The undersigned (the “Investor”)
hereby confirms its agreement with you as follows:


  1. This
  Subscription Agreement (this “Agreement”) is made as of the
  date set forth below between Genta Incorporated, a Delaware corporation (the “Company”),
and the Investor.


  2. The Company
  has authorized the sale and issuance to certain investors of up to 19,060,000
  shares (the “Shares”) of its Common
Stock, par value $0.001 per share (the “Common Stock”), subject to adjustment by the Company’s Board of Directors, or a committee thereof, for a purchase price of
$0.92 per share (the “Purchase Price”).


  3. The offering
  and sale of the Shares (the “Offering”) are being made pursuant
  to an effective Registration Statement on Form S-3 (including the Prospectus
  contained therein (the “Base Prospectus”), the “Registration Statement”)
  filed by the Company with the Securities and Exchange Commission (the “Commission”)
  and a Prospectus Supplement (the “Prospectus Supplement” and,
  together with the Base Prospectus, the “Prospectus”) containing certain supplemental information regarding the Shares and terms of the Offering that will
be filed with the Commission and delivered to the Investor along with the Company’s
counterpart to this Agreement.


  4. The Company and the Investor agree that the Investor will purchase from the Company and the Company will issue and sell to the Investor the number of Shares of Common Stock set forth below for
the aggregate purchase price set forth below. The Shares shall be purchased pursuant to the Terms and Conditions for Purchase of Shares attached hereto as Annex I and
incorporated herein by this reference as if fully set forth herein. The Investor
acknowledges that the offering is not being underwritten by the placement agent
(the “Placement Agent”) named in the
Prospectus Supplement and that there is no minimum offering amount.


  5. The manner of settlement of the Shares purchased by the Investor shall be determined by such Investor as follows (check one):

	[____] A.	 Delivery by electronic book-entry
        at The Depository Trust Company (“DTC”),
        registered in the Investor’s name and address as set forth below,
        and released by Mellon Investor Services, the Company’s transfer
        agent (the “Transfer Agent”), to the Investor at the
    Closing. NO LATER
    THAN ONE (1) BUSINESS DAY AFTER THE
    EXECUTION OF THIS AGREEMENT BY THE INVESTOR AND THE COMPANY, THE INVESTOR
    SHALL: 
	 	 


	 	
      (I)        	
      DIRECT THE BROKER-DEALER AT WHICH THE ACCOUNT OR ACCOUNTS TO BE CREDITED WITH THE SHARES ARE MAINTAINED TO SET UP A      DEPOSIT/WITHDRAWAL AT CUSTODIAN (“DWAC”)
      INSTRUCTING THE TRANSFER AGENT TO CREDIT SUCH ACCOUNT OR ACCOUNTS WITH
    THE SHARES, AND 
	 
	 	
      (II)       	
      REMIT BY WIRE TRANSFER THE AMOUNT OF FUNDS EQUAL TO THE AGGREGATE PURCHASE PRICE FOR THE SHARES BEING PURCHASED BY THE      INVESTOR TO THE FOLLOWING ACCOUNT: 
	 
	 












 


	 	
      
        
          PNC Bank Of New Jersey

            ABA#: 031-207-607

                                  Lowenstein Sandler PC Attorney Trust Account

            Account #: 8100612350

        

      

    

	 	 
	 – OR –
	 
	 	 
	[____] B.	  Delivery versus payment (“DVP”)
          through DTC (i.e., the Company shall deliver Shares registered in the
          Investor’s name and address as set forth below and released by
          the Transfer Agent to the Investor at the Closing directly to the account(s)
          at Piper Jaffray & Co. identified by the Investor and simultaneously
          therewith payment shall be made from such account(s) to the Company
          through DTC). NO LATER THAN ONE (1) BUSINESS DAY AFTER THE EXECUTION
          OF THIS AGREEMENT
    BY THE INVESTOR AND THE COMPANY, THE INVESTOR SHALL: 
	 	 



	 	
      (I)        	
      NOTIFY PIPER JAFFRAY & CO. OF THE ACCOUNT OR ACCOUNTS AT PIPER JAFFRAY & CO.
    TO BE CREDITED WITH THE SHARES BEING PURCHASED BY      SUCH INVESTOR, AND 
	 
	 	
      (II)       	
      CONFIRM THAT THE ACCOUNT OR ACCOUNTS
      AT PIPER JAFFRAY & CO., TO BE CREDITED WITH THE SHARES BEING PURCHASED
    BY THE INVESTOR      HAVE A MINIMUM BALANCE EQUAL TO THE
    AGGREGATE PURCHASE PRICE FOR THE SHARES BEING PURCHASED BY THE INVESTOR. 



  IT IS THE INVESTOR’S RESPONSIBILITY
  TO (A) MAKE THE NECESSARY WIRE TRANSFER OR CONFIRM THE PROPER ACCOUNT BALANCE
  IN A TIMELY MANNER AND (B) ARRANGE FOR SETTLEMENT BY WAY OF DWAC OR DVP IN
  A TIMELY MANNER. IF THE INVESTOR DOES NOT DELIVER THE AGGREGATE PURCHASE PRICE
  FOR THE SHARES OR DOES NOT MAKE PROPER ARRANGEMENTS FOR SETTLEMENT IN A TIMELY
  MANNER, THE SHARES MAY NOT BE DELIVERED AT CLOSING TO THE INVESTOR OR THE INVESTOR
MAY BE EXCLUDED FROM THE CLOSING ALTOGETHER.


  6. The Investor represents that, except as set forth below, (a) it has had no position, office or other material relationship within the past three years with the Company or persons known to it to
be affiliates of the Company, (b) it is not a NASD member or an Associated Person (as such term is defined under the NASD Membership and Registration Rules Section 1011) as of the Closing, and (c) neither the Investor nor any group of Investors (as
identified in a public filing made with the Commission) of which the Investor is a part in connection with the offering of the Shares, acquired, or obtained the right to acquire, 20% or more of the Common Stock (or securities convertible or
exercisable for Common Stock) or the voting power of the Company on a post-transaction basis. Exceptions:





(If no exceptions, write “none.” If left blank, response will be deemed to be “none.”)
  




  7. The Investor
  represents that it has received the Base Prospectus, dated May 11, 2004, which
  is a part of the Company’s Registration Statement, prior to or in connection
with the receipt of this Agreement.

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	Number of Shares:	 
    	 
	 	 	 



	Purchase Price Per Share: 	$0.92
    	 
	 	 	 
	Aggregate Purchase Price:	
    $
    	 
	 	 	 



       Please confirm that the foregoing correctly sets forth the agreement between us by signing in the space provided below for that purpose.


  	 Dated as of: August 5, 2005  
	 
	 
	
	 
	   INVESTOR  
	 	 
	By:	 
	 	
	 
	 Print
          Name:	 	 
	 	 	
	 
	Title:	 	 
	 	
	 
	 Address: 	 	 
	 	 	
	 
	 	 	
	 
	 	 	
	 


  

  


  
    	 Agreed and Accepted  
	 this 5th day of August 2005:  
	 	 	 
	 GENTA INCORPORATED  
	 	 	 
	By:	 
	 	

	 Title:
	 	



  

  

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  ANNEX I


  TERMS AND CONDITIONS FOR PURCHASE OF SHARES


       1. Authorization
  and Sale of the Shares. Subject to the terms and conditions of this Agreement, the Company has authorized the sale of
the Shares.


    2. Agreement to Sell and Purchase the
Shares; Placement Agent.


            2.1 At
  the Closing (as defined in Section 3.1),  the
  Investor will purchase from the Company, upon the terms and conditions set
  forth herein, the number of Shares set forth on the last page of the Agreement
  to which these Terms and Conditions for Purchase of Shares are attached as Annex
  I (the “Signature Page”)
for the aggregate purchase price therefor set forth on the Signature Page.


            2.2 The
  Company proposes to enter into substantially this same form of Subscription
  Agreement with certain other investors (the “Other Investors”)
  and expects to complete sales of Shares to them. The Investor and the Other
  Investors are hereinafter sometimes collectively referred to as the “Investors,” and
  this Agreement and the Subscription Agreements executed by the Other Investors
are hereinafter sometimes collectively referred to as the “Agreements.”


            2.3 Investor
  acknowledges that the Company intends to pay Piper Jaffray & Co. (the “Placement Agent”)
  a fee (the “Placement Fee”) in respect of the sale of Shares
to the Investor.


            2.4 The
  Company has entered into a Placement Agent Agreement (the “Placement Agreement”),
  dated August 5, 2005 with the Placement Agent that contains certain representations,
  warranties, covenants, agreements and indemnities of the Company that may be
  relied upon by the Investor, which shall be a third party beneficiary thereof.
A copy of the Placement Agreement is available upon request.


       3. Closings and Delivery of the Shares
and Funds.


            3.1 Closing. The
  completion of the purchase and sale of the Shares (the “Closing”)
  shall occur at a place and time (the “Closing Date”) to be
  specified by the Company and the Placement Agent, and of which the Investors
  will be notified in advance by the Placement Agent in accordance with Rule
  15c6-1 promulgated under the Securities Exchange Act of 1934, as amended. At
  the Closing, (a) the Company shall cause the Transfer Agent to deliver to the
  Investor, the number of Shares set forth on the Signature Page registered in
  the name of the Investor or, if so indicated on the Investor Questionnaire
  attached hereto as Exhibit
  A, in the name of a nominee designated by the Investor and (b) the aggregate purchase price for the Shares being purchased by the Investor will be delivered by or on behalf of the Investor
to the Company.


            3.2 (a) Conditions
  to the Company’s Obligations.  The
  Company’s obligation to issue and sell the Shares to the Investor shall
  be subject to: (a) the receipt by the Company of the purchase price for the
  Shares being purchased hereunder as set forth on the Signature Page and (b)
  the accuracy of the representations and warranties made by the Investor and
  the fulfillment of those undertakings of the Investor to be fulfilled prior
to the Closing Date.


                  (b) Conditions
  to the Investor’s Obligations.  The
  Investor’s obligation to purchase the
Shares will be subject to the condition that the Placement Agent shall not have: (a) terminated the Placement Agreement pursuant to the terms thereof or (b) determined that the conditions to closing in the Placement Agency Agreement have not been
satisfied. The Investor’s obligations are expressly not conditioned on the
purchase by any or all of the other Investors of the Shares that they have agreed
to purchase from the Company.


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            3.3 Delivery of Funds.


             (a) Delivery
  by Electronic Book-Entry at The Depository Trust Company. If the Investor
  elects to settle the Shares purchased by such Investor  through delivery by
  electronic book-entry at DTC, no later than one (1) business day after
  the execution of this Agreement by the Investor and the Company,
the Investor shall remit by wire transfer the amount of funds equal to the aggregate
purchase price for the shares being purchased by the Investor to the following
account designated by the Company and the Placement Agent pursuant to the terms
of that certain Escrow Agreement (the “Escrow Agreement”) dated
as of August 5, 2005, by and among the Company, the Placement Agent and Lowenstein
Sandler PC (the “Escrow
Agent”):


  
    
      
        
          
            
              PNC Bank Of New Jersey

              ABA#: 031-207-607

              Lowenstein Sandler PC Attorney Trust Account

                        Account
                        #: 8100612350

          

        

      

    

  




            Such funds
  shall be held in escrow until the Closing and delivered by the Escrow Agent
  on behalf of the Investors to the Company upon the satisfaction, in the sole
  judgment of the Placement Agent, of  the conditions set forth in Section 3.2(b)
  hereof. The Placement Agent shall have no rights in or to any of the escrowed
  funds, unless the Placement Agent and the Escrow Agent are notified in writing
  by the Company in connection with the Closing  that a portion of the escrowed
  funds shall be applied to the Placement Fee. The Company and the Investor agree
  to indemnify and hold the Escrow Agent harmless from and against any and all
  losses, costs, damages, expenses and claims (including,  without limitation,
  court costs and reasonable attorneys fees) (“Losses”)
  arising under this Section 3.3 or otherwise with respect to the funds held in escrow
pursuant hereto or arising under the Escrow Agreement, unless it is finally determined that such Losses resulted directly from the willful misconduct or gross negligence of the Escrow Agent.  Anything in this Agreement to the contrary
notwithstanding, in no event shall the Escrow Agent be liable for any special, indirect or consequential loss or damage of any kind whatsoever (including but not limited to lost profits), even if the Escrow Agent has been advised of the likelihood
of such loss or damage and regardless of the form of action.


            Investor acknowledges that the Escrow Agent acts as counsel to the Placement Agent, and shall have the right to continue to represent the Placement Agent, in any action, proceeding, claim, litigation,
dispute, arbitration or negotiation in connection with the Offering, and Investor hereby consents thereto and waives any objection to the continued representation of the Placement Agent by the Escrow Agent in connection therewith based upon the
services of the Escrow Agent under the Escrow Agreement, without waiving any duty or obligation the Escrow Agent may have to any other person.


            (b) Delivery Versus Payment through The Depository Trust Company.  If the Investor elects to settle the Shares purchased by such Investor by
delivery versus payment through DTC, no later than one (1) business day after the execution of this Agreement by the Investor and the Company,
the Investor shall confirm that the account or accounts at Piper Jaffray & Co.
to be credited with the Shares being purchased by the Investor have a minimum
balance equal to the aggregate purchase price for the Shares being purchased
by the Investor. 

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            3.4 Delivery of Shares.


        (a) Delivery
by Electronic Book-Entry at The Depository Trust Company. If the Investor
elects to settle the Shares purchased by such Investor through delivery by electronic
book-entry at DTC, no
  later than one (1) business day after the execution of this Agreement by the
   Investor and the Company, the Investor shall
direct the broker-dealer at which the account or accounts to be credited with
the Shares being purchased by such Investor are maintained, which broker/dealer
shall be a DTC participant, to set up a Deposit/Withdrawal at Custodian (“DWAC”)
instructing Mellon Financial Services, the Company’s
transfer agent, to credit such account or accounts with the Shares by means of
an electronic book-entry delivery. Such DWAC shall indicate the settlement date
for the deposit of the Shares, which date shall be provided to the Investor by
the Placement Agent. Simultaneously with the delivery to the Company by the Escrow
Agent of the funds held in escrow pursuant to Section 3.3 above, the Company
shall direct its transfer agent to credit the Investor’s account or accounts
with the Shares pursuant to the information contained in the DWAC.


            (b) Delivery Versus Payment through The Depository Trust Company.  If the Investor elects to settle the Shares purchased by such Investor by
delivery versus payment through DTC, no later than one (1) business day after the execution of this Agreement by the Investor and the Company,
the Investor shall notify Piper Jaffray & Co. of the account or accounts at Piper Jaffray & Co. to be credited with the Shares being purchased by such Investor. On the Closing Date, the Company shall deliver the Shares to the Investor directly to the account(s) at Piper Jaffray
& Co. identified by Investor and simultaneously therewith payment shall be
made from such account(s) to the Company through DTC.


       4. Representations, Warranties and Covenants
of the Investor.


            4.1 Investor
  has answered all questions on the Signature Page and Exhibit
  A attached
  hereto for use in preparation of the Prospectus Supplement and the answers
  thereto are true and correct as of the date hereof and will be true and correct
  as of the Closing Date and (b) the Investor, in connection with its decision
  to purchase the number of Shares set forth on the Signature Page, relied only
  upon the Prospectus, the Company’s regular reports on Forms 10-K, 10-Q
  and 8-K as filed by the Company with the Commission, and the representations
and warranties of the Company contained herein.


            4.2 The Investor acknowledges, represents and agrees that no action has been or will be taken in any jurisdiction outside the United States by the Company or any
Placement Agent that would permit an offering of the Shares, or possession or distribution of offering materials in connection with the issue of the Shares in any jurisdiction outside the United States where action for that purpose is required. Each
Investor outside the United States will comply with all applicable laws and regulations in each foreign jurisdiction in which it purchases, offers, sells or delivers Shares or has in its possession or distributes any offering material, in all cases
at its own expense.


            4.3 The
  Investor further represents and warrants to, and covenants with, the Company
  that (a) the Investor has full right, power, authority and capacity to enter
  into this Agreement and to consummate the transactions contemplated hereby
  and has taken all necessary action to authorize the execution, delivery and
  performance of this Agreement, and (b) this Agreement constitutes a valid and
  binding obligation of the Investor enforceable against the Investor in accordance
  with its terms, except as enforceability may be limited by applicable bankruptcy,
  insolvency, reorganization, moratorium or similar laws affecting creditors’ and contracting parties’ rights
  generally and except as enforceability may be subject to general principles
  of equity (regardless of whether such enforceability is considered in a proceeding
  in equity or at law) and except as the indemnification agreements of the Investors
herein may be legally unenforceable.


            4.4 The Investor understands that nothing in this Agreement, the Prospectus or any other materials presented to the Investor in connection with the purchase and sale
of the Shares constitutes legal, tax


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  or investment advice.  The Investor has consulted such legal, tax and investment advisors as it, in its sole discretion, has deemed necessary or appropriate in connection with its purchase of Shares.


            4.5 The
  Investor represents, warrants and agrees that, since the earlier to occur of
  (i) the date on which any of the Company or the Placement Agent first contacted
  the Investor about the potential sale of the Shares and (ii) the date that
  is the tenth (10th) trading day prior to the date of this Agreement, it has
  not engaged in any transactions in the securities of the Company (including,
  without limitation, any Short Sales involving the Company’s securities). Such Investor covenants that it will not engage in any transactions in the securities of the Company (including Short Sales) prior to the time that the transactions contemplated by this
Agreement are publicly disclosed. Each Investor agrees that it will not use any of the Shares acquired pursuant to this Agreement to cover any short position in the Common Stock if doing so would be in violation of applicable securities laws. For
purposes hereof, “Short Sales” include, without limitation, all “short sales” as defined in Rule 3b-3 of the Exchange Act and Rule 200 promulgated under Regulation SHO under the Exchange Act, whether or not against the box, and
all types of direct and indirect stock pledges, forward sale contracts, options, puts, calls, short sales, swaps, “put equivalent positions” (as
defined in Rule 16a-1(h) under the Exchange Act) and similar arrangements (including
on a total return basis), and sales and other transactions through non-US broker
dealers or foreign regulated brokers.


       5. Survival
  of Representations, Warranties and Agreements. Notwithstanding any investigation made by any party to this Agreement or
by the Placement Agent, all covenants, agreements, representations and warranties made by the Company and the Investor herein will survive the execution of this Agreement, the delivery to the Investor of the Shares being purchased and the payment
therefor.


       6. Notices. All notices, requests, consents and other communications hereunder will be in writing, will be mailed (a) if within the
domestic United States by first-class registered or certified airmail, or nationally recognized overnight express courier, postage prepaid, or by facsimile or (b) if delivered from outside the United States, by International Federal Express or
facsimile, and will be deemed given (i) if delivered by first-class registered or certified mail domestic, three business days after so mailed, (ii) if delivered by nationally recognized overnight carrier, one business day after so mailed, (iii) if
delivered by International Federal Express, two business days after so mailed and (iv) if delivered by facsimile, upon electric confirmation of receipt and will be delivered and addressed as follows:


     (a)  if
to the Company, to: 


  
     Genta Incorporated

      Two
        Connell Drive

      Berkeley Heights, New Jersey
            07922

      Attention: William P. Keane

      Phone:
        (908) 286-6444

      Telecopy: (908) 286-6450

     with copies to: 

     Davis Polk & Wardwell

    450
        Lexington Avenue

      New York, NY 10017

    Attention:
        Richard A. Drucker, Esq.

    Phone: (212)
    450-4745

    Telecopy: (212) 450-3745 

  



      (b) if
            to the Investor, at its address on the Signature Page hereto, or at
            such other address or addresses as may have been furnished to
      the Company in writing.



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       7. Changes. This Agreement may not be modified or amended except pursuant to an instrument in writing signed by the Company and the
Investor.


       8. Headings. The headings of the various sections of this Agreement have been inserted for convenience of reference only and will not
be deemed to be part of this Agreement.


       9. Severability. In case any provision contained in this Agreement should be invalid, illegal or unenforceable in any respect, the
validity, legality and enforceability of the remaining provisions contained herein will not in any way be affected or impaired thereby.


       10. Governing
  Law. This Agreement will be governed by, and construed in accordance with, the internal laws of the State of New York,
without giving effect to the principles of conflicts of law that would require the application of the laws of any other jurisdiction.


       11. Counterparts. This Agreement may be executed in two or more counterparts, each of which will constitute an original, but all of
which, when taken together, will constitute but one instrument, and will become effective when one or more counterparts have been signed by each party hereto and delivered to the other parties.  The Company and the Investor acknowledge and agree
that the Company shall deliver its counterpart to the Investor along with the Prospectus Supplement.


       12. Confirmation
  of Sale. The Investor acknowledges and agrees
  that such Investor’s receipt of the Company’s counterpart to
this Agreement, together with the Prospectus Supplement, shall constitute written confirmation of the Company’s
sale of Shares to such Investor.


       13. Press
  Release.  The Company and the Investor agree that the Company shall issue a press release announcing the transaction prior
to the opening of the financial markets in New York City on the business day immediately after the date hereof.


       14. Termination.  In the event that the Placement Agreement is terminated by the Placement Agents pursuant to the terms thereof, this
Agreement shall terminate without any further action on the part of the parties hereto.


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  EXHIBIT A


  GENTA INCORPORATED


  INVESTOR QUESTIONNAIRE


       Pursuant to Section 3 of Annex I to the Agreement, please provide us with the
following information:

	 	
      1.       	
      The exact name that your Shares are to be registered in. You may use a nominee name if appropriate:    	 
    
	 
	 	
      2.       	
      The relationship between the Investor and the registered holder listed in response to item 1 above:    	 
    
	 
	 	
      3.       	
      The mailing address of the registered holder listed in response to item 1 above:       	 
    
	 
	 	
      4.       	
      The Social Security Number or Tax Identification Number of the registered holder listed in the response to item 1 above:       	 
    
	 
	 	
      5.       	
      Name of DTC Participant (broker-dealer at which the account or accounts to be credited with the Shares are maintained) 	 
    
	 
	 	
      6.       	
      DTC Participant Number 	 
    
	 
	 	
      7.       	
      Name of Account at DTC Participant being credited with the Shares      	 
    
	 
	 	
      8.       	
      Account Number at DTC Participant being credited with the Shares