[Federal Register Volume 87, Number 133 (Wednesday, July 13, 2022)]
[Notices]
[Page 41721]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2022-14906]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[CDC-2019-0015, Docket Number NIOSH-153-E]


Publication of Skin Notation Profile Documents for Chlorodiphenyl 
(54% Chlorine) (CAS: 11097-69-1), Diacetyl and 2,3-Pentanedione (CAS: 
431-03-8; 600-14-6), Dioxane (CAS: 123-91-1), Beta Chloroprene (CAS: 
126-99-8), and 2,4-Toluene Diisocyanate, 2,6-Toluene Diisocyanate, and 
2,4- and 2,6-Toluene Diisocyanate Mixture (CAS: 584-84-9; 91-08-7; 
26471-62-5 (as a Mixture))

AGENCY: The Centers for Disease Control and Prevention (CDC), 
Department of Health and Human Services (HHS).

ACTION: Notice of availability.

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SUMMARY: The National Institute for Occupational Safety and Health 
(NIOSH) in the Centers for Disease Control and Prevention (CDC), an 
operating division of the Department of Health and Human Services 
(HHS), announces the availability of five documents, the Skin Notation 
Profiles for Chlorodiphenyl (54% chlorine) (CAS: 11097-69-1), Diacetyl 
and 2,3-Pentanedione (CAS: 431-03-8; 600-14-6), Dioxane (CAS: 123-91-
1), beta Chloroprene (CAS: 126-99-8), and 2,4-Toluene diisocyanate, 
2,6-Toluene diisocyanate, and 2,4- and 2,6-Toluene diisocyanate mixture 
(CAS: 584-84-9; 91-08-7; 26471-62-5 (as a mixture)).

DATES: The final documents were published on July 7, 2022 on the CDC 
website.

ADDRESSES: The documents may be obtained at the following links:
    Chlorodiphenyl (54% chlorine) (CAS: 11097-69-1): https://www.cdc.gov/niosh/docs/2022-118/;
    Diacetyl and 2,3-Pentanedione (CAS: 431-03-8; 600-14-6): https://www.cdc.gov/niosh/docs/2022-116/;
    Dioxane (CAS: 123-91-1): https://www.cdc.gov/niosh/docs/2022-114/;
    beta Chloroprene (CAS: 126-99-8): https://www.cdc.gov/niosh/docs/2022-115/;
    2,4-Toluene diisocyanate, 2,6-Toluene diisocyanate, and 2,4- and 
2,6-Toluene diisocyanate mixture (CAS: 584-84-9; 91-08-7; 26471-62-5 
(as a mixture)): https://www.cdc.gov/niosh/docs/2022-117/.

FOR FURTHER INFORMATION CONTACT: Naomi Hudson, NIOSH, 1090 Tusculum 
Ave., MS C-15, Cincinnati, OH 45226; Telephone 513-533-8388; Email: 
<a href="/cdn-cgi/l/email-protection#224b57581a624146410c454d54"><span class="__cf_email__" data-cfemail="127b67682a527176713c757d64">[email protected]</span></a>.

SUPPLEMENTARY INFORMATION: On March 15, 2019, NIOSH published a request 
for public comment in the Federal Register [Federal Register Number 
2019-04794] [84 FR 9524] on the draft versions of the following skin 
notation profile documents:

Beta-Chloroprene (CAS: 126-99-8)
Cyclohexanol (CAS: 108-93-0)
Cyclohexanone (CAS: 108-94-1)
Cyclonite (CAS: 121-82-4)
Dioxane (CAS: 123-91-1)
Diacetyl/2,3-Pentanedione (CAS: 431-03-8; 600-14-6)
Diethylenetriamine (CAS: 111-40-0)
Chlorodiphenyl (42% chlorine) (CAS: 53469-21-9)
Chlorodiphenyl (54% chlorine) (CAS: 11097-69-1)
Toluene diisocyanates (CAS: 584-84-9; 91-08-7; 26471-62-5)

    This notice announces that five of these documents have been 
finalized and published: Chlorodiphenyl (54% chlorine) (CAS: 11097-69-
1), Diacetyl and 2,3-Pentanedione (CAS: 431-03-8; 600-14-6), Dioxane 
(CAS: 123-91-1), beta Chloroprene (CAS: 126-99-8), and 2,4-Toluene 
diisocyanate, 2,6-Toluene diisocyanate, and 2,4- and 2,6-Toluene 
diisocyanate mixture (CAS: 584-84-9; 91-08-7; 26471-62-5 (as a 
mixture)). All comments received were carefully reviewed and addressed, 
where relevant. In response to comments received, revisions were made 
to clarify the data used by NIOSH in its support of the development of 
the skin notation assignments for these chemicals. NIOSH Skin Notation 
Profiles, Group E Responses to Peer Review and Public Comments can be 
found in the Supporting Documents section on www.regulations.gov for 
the CDC-2019-0015 docket.
    The other five documents were previously published in the Federal 
Register [Federal Register Number 2020-25300] [85 FR 73481] on November 
18, 2020 (https://www.federalregister.gov/documents/2020/11/18/2020-25300/skin-notation-profiles-for-chlorodiphenyl-42-chlorine-cas-53469-21-9-cyclohexanol-cas-108-93-0): Chlorodiphenyl (42% chlorine) (CAS: 
53469-21-9), Cyclohexanol (CAS: 108-93-0), Cyclohexanone (CAS: 108-94-
1), Cyclonite (CAS: 121-82-4), and Diethylenetriamine (CAS: 111-40-0).

John J. Howard,
Director, National Institute for Occupational Safety and Health, 
Centers for Disease Control and Prevention.
[FR Doc. 2022-14906 Filed 7-12-22; 8:45 am]
BILLING CODE 4163-18-P


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