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[ILLUMINA LOGO]

                                                                   Exhibit 10.30

February 14, 2005

Scott Kahn

Re: Illumina, Inc.

Dear Scott;

It gives me great pleasure to set forth the principal terms for you to join
Illumina, Inc. (the "Company").

Position:           VP and Chief Information Officer

Responsibilities:   The Chief Information Officer is a position of strategic and
                    technical leadership having responsibility for all of the
                    scientific software and IT activities of the Company as well
                    as leadership of specific projects. Principal
                    responsibilities include:

                       -  Direct reporting responsibility for the
                          Bioinformatics, LIMS, software development and IT
                          functions.

                       -  Development of strategies to use information
                          technology as a competitive advantage

                       -  Economically scaling internal information systems to
                          match the growth in product volume and complexity

                       -  Unifying the software architecture of the Company's
                          internal systems and external products

                       -  Externally representing the company on issues related
                          to information systems

                       -  Interacting with customers as part of the sales
                          process

                       -  Participating with the senior management team to
                          define the overall evolution of Illumina's products

                       -  Leading key development projects as SupraProject
                          manager.

                       -  Facilitating implementation of our e-commerce

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                          systems

                       -  Assuming responsibility for implementation and
                          monitoring of the company's Sarbanes-Oxley IT
                          obligations

                       -  Providing vision for the evolution of our application
                          software

                       -  Other such matters that may be determined by the
                          management team.

                    As a Company employee you will be expected to abide by all
                    the Company policies and procedures and sign and comply with
                    the Company's standard form of Proprietary Information and
                    Inventions Agreement, which prohibits unauthorized use or
                    disclosure of the Company's proprietary information. In
                    compliance with federal immigration law, you will be
                    required to provide documentary evidence of your identity
                    and eligibility of employment in the United States.

Reporting:          Reporting to Jay Flatley, President and CEO.
(Direct Mgr)

Compensation:       For full-time regular employment, your base salary will be
                    $8653.85, payable every other week, one week in arrears and
                    subject to standard payroll deductions and withholdings.
                    Your first paycheck will be prorated based on your
                    employment start date.

Equity:             Subject to approval by the Stock Option Committee, you will
                    be granted an option to purchase 100,000 shares of Common
                    Stock at a purchase price equal to the closing price of such
                    shares on your first day of employment. The shares are
                    subject to standard vesting over a five-year period, with
                    20% of the shares vesting after one year from employment
                    Start Date of your full-time employment and thereafter
                    1/60th per month for the remaining 48 months. The options
                    will be granted pursuant to the Company's 2000 Stock Plan.

Executive Bonus:    You will participate in our Executive Bonus Plan at a 20%
                    level. Your first year's pay out will be prorated, based on
                    the number of full months that you are on board. Plans are
                    currently being developed, and are based on both Corporate
                    financial targets (2/3 of pay out) and personal objectives
                    (1/3 of pay out).

Benefits:           You will be entitled to receive the Company's standard

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                    benefits. These include medical, dental and vision
                    insurance, which begin the first day of the following month
                    after your hire. Life insurance, long/short-term disability
                    insurance, employee assistance plan and 401(k) begin on your
                    date of hire.

Employment          at Will: Your employment will be at-will, which means it may
                    be terminated at any time by you or the Company for any
                    reason or for no reason. This at-will employment
                    relationship cannot be changed except by written agreement
                    signed by the CEO of the Company.

Start Date:         Your first day of full-time regular employment will be March
                    28th, or an otherwise mutually agreeable date.

Expiration of       This offer will be valid for 7 days from the date of this
Offer:              letter.

This letter contains the complete, final and exclusive embodiment of the terms
of your employment with the Company. This letter shall be governed by California
law without regard to conflict of laws principles.

We hope that you will join us in building a pre-eminent life sciences company.
If the foregoing accurately reflects our agreement, please so indicate by
signing where indicated below and returning the enclosed duplicate copy of this
letter to me.

Sincerely,

Jay Flatley
President and CEO
Illumina, Inc.

The foregoing is agreed and accepted.

__________________________________                     _________________________
           Scott Kahn                                       Date

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