Exhibit 10.8

                               AMENDMENT NO. 1 TO

                             STOCK OPTION AGREEMENT

                                 pursuant to the

                                  LABONE, INC.

                          2001 LONG-TERM INCENTIVE PLAN

                             STOCK INCENTIVE PROGRAM

     This AMENDMENT NO. 1 TO STOCK OPTION AGREEMENT ("Amendment") is dated as of
_____________ and entered into by and between LabOne, Inc. ("LabOne"), a
Missouri corporation, and _____________________ ("Optionee").

      WITNESSETH that:

      WHEREAS, LabOne and the Optionee are parties to one or more Stock Option
Agreements relating to stock options (individually the "Stock Option Agreement"
or collectively the "Stock Option Agreements") granted under the Stock Incentive
Program of the LabOne, Inc. 2001 Long-Term Incentive Plan (the "Plan"); and

      WHEREAS, LabOne and the Optionee desire to amend the Stock Option
Agreements to (a) provide that such stock options shall become fully exercisable
upon consummation of a merger or consolidation of LabOne with another
corporation rather than upon shareholder approval of such a transaction and (b)
provide that acceleration of vesting, exercise (if such stock options are
exercised) and termination of such stock options in connection with a Corporate
Transaction (as hereinafter defined) will be subject to the condition that the
Corporate Transaction is consummated; and

      WHEREAS, it is in the best interests of LabOne and the Optionee to include
such provisions in order for LabOne to be able to engage in one or more
Corporate Transactions;

      NOW, THEREFORE, in consideration of the terms and provisions of this
Amendment and other good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged by the parties hereto, the parties hereto agree
as follows:

     Section 1. Section 3(b)(iii) of each outstanding Stock Option Agreement is
hereby amended to read as follows:

     (iii) LabOne merges or consolidates with another corporation or
     other entity, unless such merger of consolidation (A) is approved
     by a majority of the Continuing Directors of


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     LabOne, and (B) is specifically designated by a majority of the
     Continuing Directors not to constitute a change of control for
     purposes of the Plan; or

     Section 2.   Section 8 of each outstanding Stock Option Agreement is
hereby amended to read as follows:

          In the event that the Board of Directors of LabOne approves
          (a) the merger or consolidation of LabOne with or into
          another corporation or other entity in which the
          shareholders of LabOne immediately prior to such transaction
          will beneficially own no voting securities or voting
          securities possessing less than 50% of the combined voting
          power of the then outstanding securities of the surviving
          entity in such transaction (or its parent), excluding for
          purposes of such calculation any such shareholder of LabOne
          who beneficially owns prior to the transaction more than ten
          percent (10%) of the other entity involved in the
          transaction (or its parent), (b) a sale of all or
          substantially all of the assets of LabOne in which
          outstanding securities of LabOne are exchanged for
          securities, cash or other property of any corporation or
          other entity or (c) a liquidation or dissolution of LabOne
          (collectively, a "Corporate Transaction"); the Board of
          Directors of LabOne may in its sole discretion prior to
          consummation of such transaction take any one or more of the
          following actions with respect to the Option: (i) provide
          that the Option shall be assumed or an equivalent stock
          option shall be substituted by the acquiring or succeeding
          corporation or entity (or an affiliate thereof) or (ii) upon
          thirty (30) days' prior written notice to the Optionee,
          provide that the Option shall be exercisable in full and
          shall terminate at the end of such thirty (30) day period to
          the extent not exercised by such time, at the end of which
          period the Option shall terminate; provided, however, that
          unless determined otherwise by the Board, the acceleration
          of vesting, exercise (if such Option is exercised) and
          termination of such Option under clause (ii) shall be
          subject to the condition that the respective Corporate
          Transaction shall be consummated and such acceleration of
          vesting, exercise (if such Option is exercised) and
          subsequent termination of such Option shall be effective
          immediately prior to the effectiveness of the respective
          Corporate Transaction.

      Section 3.   A new Section 8A is added to each Stock Option Agreement and
reads as follows:

          In the event that this Option is exercised pursuant to
          clause (ii) of Section 8 in connection with a Corporate
          Transaction in which shares of common stock of LabOne are
          converted into the right to receive cash, unless the
          Optionee elects in writing at the time the Option is
          exercised pursuant to clause (ii) of Section 8 to receive
          the Shares issuable upon exercise, (a) the Optionee will be
          entitled to receive upon effectiveness of such exercise, in
          lieu of Shares issuable in


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          connection with such exercise of the Option, an amount in
          cash equal to the number of Shares subject to the Option
          immediately prior to such exercise multiplied by the amount
          by which the cash consideration per Share payable in such
          Corporate Transaction exceeds the exercise price per Share,
          subject to all applicable federal, state and local tax
          withholding requirements, and (b) the Optionee shall not be
          required to pay the exercise price in connection with such
          exercise.

      Section 4.   The remaining provisions of each Stock Option Agreement shall
apply to this Amendment and to such Stock Option Agreement as amended by this
Amendment.

      IN WITNESS WHEREOF, LabOne, Inc. has caused this Amendment to be executed
in its corporate name, and the Optionee has executed the same in evidence of the
Optionee's acceptance hereof, upon the terms and conditions herein set forth, as
of the day and year first above written.

                               LABONE, INC.



                               By:
                                  ----------------------------
                                    Name:
                                    Title:



                               -------------------------------
                               Optionee