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 Environmental Protection Agency 40 CFR Parts 9 and 721
[EPA-HQ-OPPT-2019-0494; FRL-7584-01-OCSPP]
RIN 2070-AB27
 AGENCY: Environmental Protection Agency (EPA).
 ACTION: Final rule.
 SUMMARY: EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for chemical substances which were the subject of premanufacture notices (PMNs). This action requires persons to notify EPA at least 90 days before commencing manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use by this rule. This action further requires that persons not commence manufacture or processing for the significant new use until they have submitted a Significant New Use Notice (SNUN), and EPA has conducted a review of the notice, made an appropriate determination on the notice, and has taken any risk management actions as are required as a result of that determination.
 DATES: This rule is effective on August 26, 2022. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (e.s.t.) on July 11, 2022.
 FOR FURTHER INFORMATION CONTACT: *For technical information contact:*
                         William Wysong, New Chemicals Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: (202) 564-4163; email address: 
                        *wysong.william@epa.gov.* *For general information contact:*
                         The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; email address: 
                        *TSCA-Hotline@epa.gov.*


SUPPLEMENTARY INFORMATION: I. General Information A. Does this action apply to me? You may be potentially affected by this action if you manufacture, process, or use the chemical substances contained in this rule. The following list of North American Industrial Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers determine whether this document applies to them. Potentially affected entities may include: Manufacturers or processors of one or more subject chemical substances (NAICS codes 325 and 324110),*e.g.,*
                     chemical manufacturing and petroleum refineries. This action may also affect certain entities through pre-existing import certification and export notification rules under TSCA. Chemical importers are subject to the TSCA section 13 (15 U.S.C. 2612) import provisions. This action may also affect certain entities through pre-existing import certification and export notification rules under TSCA, which would include the SNUR requirements. The EPA policy in 
                    ( print page 38000)
                    support of import certification appears at 40 CFR part 707, subpart B. In addition, pursuant to 40 CFR 721.20, any persons who export or intend to export a chemical substance that is the subject of this rule are subject to the export notification provisions of TSCA section 12(b) (15 U.S.C. 2611(b)), and must comply with the export notification requirements in 40 CFR part 707, subpart D. B. How can I access the docket? The docket includes information considered by the Agency in developing the proposed and final rules. The docket for this action, identified by docket identification (ID) number EPA-HQ-OPPT-2019-0494, is available at 
                    *https://www.regulations.gov*
                     and at the Office of Pollution Prevention and Toxics Docket (OPPT Docket), Environmental Protection Agency Docket Center (EPA/DC), West William Jefferson Clinton Bldg., Rm. 3334, 1301 Constitution Ave. NW, Washington, DC. The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the OPPT Docket is (202) 566-0280. Please review the visitor instructions and additional information about the docket available at 
                    *https://www.epa.gov/​dockets.* II. Background A. What action is the Agency taking? EPA is finalizing SNURs under TSCA section 5(a)(2) for chemical substances which were the subject of PMNs P-17-312, P-17-313, P-17-314, P-17-315, P-17-316, P-17-317, P-18-9, P-18-11, P-18-170, P-18-185, P-18-190, P-18-191, P-18-223, P-18-285, P-18-300, P-18-394, P-18-404, P-19-12, P-19-31, and P-19-72. These SNURs require persons who intend to manufacture or process any of these chemical substances for an activity that is designated as a significant new use to notify EPA at least 90 days before commencing that activity. EPA is not currently finalizing the SNUR for the substance which was the subject of PMN P-19-71 because the Agency has received new data on the substance. EPA will review the new data and address this proposed SNUR in a future notice. Previously, in the 
                    **Federal Register**
                     of November 4, 2019 (84 FR 59335) (FRL-10000-54), EPA proposed SNURs for these chemical substances and five other SNURs. EPA finalized the proposed SNURs for P-16-548, P-17-398, P-17-399, P-18-1, and P-18-28 in a previous 
                    **Federal Register**
                     notice of August 18, 2021 (86 FR 46133) (FRL-8000-02-OCSPP). More information on the specific chemical substances subject to this final rule can be found in the 
                    **Federal Register**
                     document proposing the SNURs. The docket includes information considered by the Agency in developing the proposed and final rules, including the public comments received on the proposed rules that are described in Unit IV. B. What is the Agency's authority for taking this action? TSCA section 5(a)(2) (15 U.S.C. 2604(a)(2)) authorizes EPA to determine that a use of a chemical substance is a “significant new use.” EPA must make this determination by rule after considering all relevant factors, including the four TSCA section 5(a)(2) factors listed in Unit III. C. Do the SNUR general provisions apply? General provisions for SNURs appear in 40 CFR part 721, subpart A. These provisions describe persons subject to the rule, recordkeeping requirements, exemptions to reporting requirements, and applicability of the rule to uses occurring before the effective date of the rule. Provisions relating to user fees appear at 40 CFR part 700. Pursuant to 40 CFR 721.1(c), persons subject to these SNURs must comply with the same SNUN requirements and EPA regulatory procedures as submitters of PMNs under TSCA section 5(a)(1)(A). In particular, these requirements include the information submission requirements of TSCA sections 5(b) and 5(d)(1), the exemptions authorized by TSCA sections 5(h)(1), 5(h)(2), 5(h)(3), and 5(h)(5) and the regulations at 40 CFR part 720. Once EPA receives a SNUN, EPA must either determine that the significant new use is not likely to present an unreasonable risk of injury or take such regulatory action as is associated with an alternative determination before manufacture or processing for the significant new use can commence. If EPA determines that the significant new use is not likely to present an unreasonable risk, EPA is required under TSCA section 5(g) to make public, and submit for publication in the 
                    **Federal Register**
                    *,*
                     a statement of EPA's findings. III. Significant New Use Determination A. Determination Factors TSCA section 5(a)(2) states that EPA's determination that a use of a chemical substance is a significant new use must be made after consideration of all relevant factors, including: The projected volume of manufacturing and processing of a chemical substance.
                The extent to which a use changes the type or form of exposure of human beings or the environment to a chemical substance.
                The extent to which a use increases the magnitude and duration of exposure of human beings or the environment to a chemical substance.
                The reasonably anticipated manner and methods of manufacturing, processing, distribution in commerce, and disposal of a chemical substance. In determining what would constitute a significant new use for the chemical substances that are the subject of these SNURs, EPA considered relevant information about the toxicity of the chemical substances and potential human exposures and environmental releases that may be associated with the substances, in the context of the four bulleted TSCA section 5(a)(2) factors listed in this unit. During its review of the chemical substances that are the subjects of these SNURs and as further discussed in Unit VI., EPA identified potential risk concerns associated with other circumstances of use that, while not intended or reasonably foreseen, may occur in the future. EPA is designating those other circumstances of use as significant new uses. B. Procedures for Significant New Uses Claimed as Confidential Business Information (CBI) By this rule, EPA is establishing certain significant new uses which have been claimed as CBI subject to Agency confidentiality regulations at 40 CFR part 2 and 40 CFR part 720, subpart E. Absent a final determination or other disposition of the confidentiality claim under 40 CFR part 2 procedures, EPA is required to keep this information confidential. EPA promulgated a procedure to deal with the situation where a specific significant new use is CBI, at 40 CFR 721.1725(b)(1) and has referenced it to apply to other SNURs. Under these procedures a manufacturer or processor may request EPA to determine whether a specific use would be a significant new use under the rule. The manufacturer or processor must show that it has a 
                    *bona fide*
                     intent to manufacture or process the chemical substance and must identify the specific use for which it intends to manufacture or process the chemical substance. If EPA concludes that the person has shown a 
                    *bona fide*
                     intent to manufacture or process the chemical substance, EPA 
                    ( print page 38001)
                    will tell the person whether the use identified in the 
                    *bona fide*
                     submission would be a significant new use under the rule. Since most of the chemical identities of the chemical substances subject to these SNURs are also CBI, manufacturers and processors can combine the 
                    *bona fide*
                     submission under the procedure in 40 CFR 721.1725(b)(1) with that under 40 CFR 721.11 into a single step. If EPA determines that the use identified in the 
                    *bona fide*
                     submission would not be a significant new use, 
                    *i.e.,*
                     the use does not meet the criteria specified in the rule for a significant new use, that person can manufacture or process the chemical substance so long as the significant new use trigger is not met. In the case of a production volume trigger, this means that the aggregate annual production volume does not exceed that identified in the 
                    *bona fide*
                     submission to EPA. Because of confidentiality concerns, EPA does not typically disclose the actual production volume that constitutes the use trigger. Thus, if the person later intends to exceed that volume, a new 
                    *bona fide*
                     submission would be necessary to determine whether that higher volume would be a significant new use. IV. Public Comments EPA received public comments from three identifying entities on the proposed rule. The Agency's responses are presented in the Response to Public Comments document that is available in the docket for this rule. Based on these comments EPA made a change to the SNUR for P-17-312 regarding calculation of surface water concentrations as described in the response to comments document. V. Substances Subject to This Rule EPA is establishing significant new use and recordkeeping requirements for chemical substances in 40 CFR part 721, subpart E. In Unit IV. of the proposed SNUR, EPA provided the following information for each chemical substance: PMN number.
                Chemical name (generic name, if the specific name is claimed as CBI).
                Chemical Abstracts Service (CAS) Registry number (if assigned for non-confidential chemical identities).
                Basis for the SNUR.
                Potentially useful information.
                CFR citation proposed to be assigned in the regulatory text section. This final rule makes the final assignment to set the CFR citation for the chemical substance. The regulatory text section of these rules specifies the activities designated as significant new uses. Certain new uses, including production volume limits and other uses designated in the rules, may be claimed as CBI. VI. Rationale and Objectives of the Rule A. Rationale The chemical substances that are the subjects of these SNURs received “not likely to present an unreasonable risk” determinations under TSCA section 5(a)(3)(C) based on EPA's review of the intended, known, and reasonably foreseen conditions of use. However, EPA has identified other circumstances that, should they occur in the future, even if not reasonably foreseen, may present risk concerns. Specifically, EPA has determined that deviations from the protective measures identified in the PMN submissions could result in changes in the type or form of exposure to the chemical substances, increased exposures to the chemical substances, and/or changes in the reasonably anticipated manner and methods of manufacturing, processing, distribution in commerce, and disposal of the chemical substances. These SNURs identify as a significant new use manufacturing, processing, use, distribution in commerce, or disposal that does not conform to the protective measures identified in the submissions. As a result, those significant new uses cannot occur without first going through a separate, subsequent EPA review and determination process associated with a SNUN. B. Objectives EPA is issuing these SNURs because the Agency wants: To have an opportunity to review and evaluate data submitted in a SNUN before the notice submitter begins manufacturing or processing a listed chemical substance for the described significant new use.
                To be obligated to make a determination under TSCA section 5(a)(3) regarding the use described in the SNUN, under the conditions of use. The Agency will either determine under section 5(a)(3)(C) that the significant new use is not likely to present an unreasonable risk, including an unreasonable risk to a potentially exposed or susceptible subpopulation identified as relevant by the Administrator under the conditions of use, or make a determination under TSCA section 5(a)(3)(A) or (B) and take the required regulatory action associated with the determination, before manufacture or processing for the significant new use of the chemical substance can occur.
                To be able to complete its review and determination on each of the PMN substances, while deferring analysis on the significant new uses proposed in these rules unless and until the Agency receives a SNUN. Issuance of a SNUR for a chemical substance does not signify that the chemical substance is listed on the TSCA Inventory. Guidance on how to determine if a chemical substance is on the TSCA Inventory is available on the internet at 
                    *https://www.epa.gov/​tsca-inventory.* VII. Applicability of the Rules to Uses Occurring Before the Effective Date of the Final Rule To establish a significant new use, EPA must determine that the use is not ongoing. The chemical substances subject to this rule have undergone premanufacture review. In cases where EPA has not received a notice of commencement (NOC) and the chemical substance has not been added to the TSCA Inventory, no person may commence such activities without first submitting a PMN. Therefore, for chemical substances for which an NOC has not been submitted, EPA concludes that the designated significant new uses are not ongoing. When the chemical substances identified in this rule are added to the TSCA Inventory, EPA recognizes that, before the rule is effective, other persons might engage in a use that has been identified as a significant new use. However, the identities of many of the chemical substances subject to this rule have been claimed as confidential (per 40 CFR 720.85). Based on this, the Agency believes that it is highly unlikely that any of the significant new uses described in the regulatory text of this rule are ongoing. EPA designated November 4, 2019 (the date of publication of the proposed rule in the 
                    **Federal Register**
                    ) as the cutoff date for determining whether the new use is ongoing. The objective of EPA's approach is to ensure that a person cannot defeat a SNUR by initiating a significant new use before the effective date of the final rule. Persons who began commercial manufacture or processing of the chemical substances for a significant new use identified on or after that date will have to cease any such activity upon the effective date of the final rule. To resume their activities, these persons would have to first comply with all applicable SNUR notification requirements and EPA would have to take action under TSCA section 5 allowing manufacture or processing to proceed.
                    ( print page 38002) VIII. Development and Submission of Information EPA recognizes that TSCA section 5 does not require development of any particular new information (
                    *e.g.,*
                     generating test data) before submission of a SNUN. There is an exception: If a person is required to submit information for a chemical substance pursuant to a rule, Order or consent agreement under TSCA section 4, then TSCA section 5(b)(1)(A) requires such information to be submitted to EPA at the time of submission of the SNUN. In the absence of a rule, Order, or consent agreement under TSCA section 4 covering the chemical substance, persons are required only to submit information in their possession or control and to describe any other information known to or reasonably ascertainable by them (see 40 CFR 720.50). However, upon review of PMNs and SNUNs, the Agency has the authority to require appropriate testing. Unit IV. of the proposed rule lists potentially useful information for all SNURs listed here. Descriptions are provided for informational purposes. The potentially useful information identified in Unit IV. of the proposed rule will be useful to EPA's evaluation in the event that someone submits a SNUN for the significant new use. Companies who are considering submitting a SNUN are encouraged, but not required, to develop the information on the substance, which may assist with EPA's analysis of the SNUN. EPA strongly encourages persons, before performing any testing, to consult with the Agency. Furthermore, pursuant to TSCA section 4(h), which pertains to reduction of testing in vertebrate animals, EPA encourages consultation with the Agency on the use of alternative test methods and strategies (also called New Approach Methodologies, or NAMs), if available, to generate the recommended test data. EPA encourages dialog with Agency representatives to help determine how best the submitter can meet both the data needs and the objective of TSCA section 4(h). For more information on alternative test methods and strategies to reduce vertebrate animal testing, visit 
                    *https://www.epa.gov/​assessing-and-managing-chemicals-under-tsca/​alternative-test-methods-and-strategies-reduce.* The potentially useful information described in Unit IV. of the proposed rule may not be the only means of providing information to evaluate the chemical substance associated with the significant new uses. However, submitting a SNUN without any test data may increase the likelihood that EPA will take action under TSCA sections 5(e) or 5(f). EPA recommends that potential SNUN submitters contact EPA early enough so that they will be able to conduct the appropriate tests. SNUN submitters should be aware that EPA will be better able to evaluate SNUNs which provide detailed information on the following: Human exposure and environmental release that may result from the significant new use of the chemical substances. IX. SNUN Submissions According to 40 CFR 721.1(c), persons submitting a SNUN must comply with the same notification requirements and EPA regulatory procedures as persons submitting a PMN, including submission of test data on health and environmental effects as described in 40 CFR 720.50. SNUNs must be submitted on EPA Form No. 7710-25, generated using e-PMN software, and submitted to the Agency in accordance with the procedures set forth in 40 CFR 720.40 and 721.25. E-PMN software is available electronically at 
                    *https://www.epa.gov/​reviewing-new-chemicals-under-toxic-substances-control-act-tsca.* X. Economic Analysis EPA has evaluated the potential costs of establishing SNUN requirements for potential manufacturers and processors of the chemical substances subject to this rule. EPA's complete economic analysis is available in the docket for this rulemaking. XI. Statutory and Executive Order Reviews Additional information about these statutes and Executive orders can be found at 
                    *https://www.epa.gov/​laws-regulations-and-executive-orders.* A. Executive Order 12866: Regulatory Planning and Review and Executive Order 13563: Improving Regulations and Regulatory Review This action establishes SNURs for new chemical substances that were the subject of PMNs. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Orders 12866 (58 FR 51735, October 4, 1993) and 13563 (76 FR 3821, January 21, 2011). B. Paperwork Reduction Act (PRA) According to PRA, 44 U.S.C. 3501 
                    *et seq.,*
                     an agency may not conduct or sponsor, and a person is not required to respond to a collection of information that requires OMB approval under PRA, unless it has been approved by OMB and displays a currently valid OMB control number. The OMB control numbers for EPA's regulations in title 40 of the CFR, after appearing in the 
                    **Federal Register**
                    *,*
                     are listed in 40 CFR part 9, and included on the related collection instrument or form, if applicable. The information collection requirements related to this action have already been approved by OMB pursuant to PRA under OMB control number 2070-0012 (EPA ICR No. 574). This action does not impose any burden requiring additional OMB approval. If an entity were to submit a SNUN to the Agency, the annual burden is estimated to average between 30 and 170 hours per response. This burden estimate includes the time needed to review instructions, search existing data sources, gather and maintain the data needed, and complete, review, and submit the required SNUN. Send any comments about the accuracy of the burden estimate, and any suggested methods for minimizing respondent burden, including through the use of automated collection techniques, to the Director, Regulatory Support Division, Office of Mission Support (2822T), Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001. Please remember to include the OMB control number in any correspondence, but do not submit any completed forms to this address. C. Regulatory Flexibility Act (RFA) Pursuant to RFA section 605(b), 5 U.S.C. 601 
                    *et seq.,*
                     I hereby certify that promulgation of this SNUR would not have a significant adverse economic impact on a substantial number of small entities. The requirement to submit a SNUN applies to any person (including small or large entities) who intends to engage in any activity described in the final rule as a “significant new use.” Because these uses are “new,” based on all information currently available to EPA, it appears that no small or large entities presently engage in such activities. A SNUR requires that any person who intends to engage in such activity in the future must first notify EPA by submitting a SNUN. Although some small entities may decide to pursue a significant new use in the future, EPA cannot presently determine how many, if any, there may be. However, EPA's experience to date is that, in response to the promulgation of SNURs covering over 1,000 chemicals, the Agency receives only a small number of notices per year. For example, the number of SNUNs received was seven in Federal fiscal 
                    ( print page 38003)
                    year (FY) 2013, 13 in FY2014, six in FY2015, 12 in FY2016, 13 in FY2017, and 11 in FY2018. Only a fraction of these were from small businesses. In addition, the Agency currently offers relief to qualifying small businesses by reducing the SNUN submission fee from $16,000 to $2,800. This lower fee reduces the total reporting and recordkeeping cost of submitting a SNUN to about $10,116 for qualifying small firms. Therefore, the potential economic impacts of complying with this SNUR are not expected to be significant or adversely impact a substantial number of small entities. In a SNUR that published in the 
                    **Federal Register**
                     of June 2, 1997 (62 FR 29684) (FRL-5597-1), the Agency presented its general determination that final SNURs are not expected to have a significant economic impact on a substantial number of small entities, which was provided to the Chief Counsel for Advocacy of the Small Business Administration. D. Unfunded Mandates Reform Act (UMRA) Based on EPA's experience with proposing and finalizing SNURs, State, local, and Tribal governments have not been impacted by these rulemakings, and EPA does not have any reasons to believe that any State, local, or Tribal government will be impacted by this action. As such, EPA has determined that this action does not impose any enforceable duty, contain any unfunded mandate, or otherwise have any effect on small governments subject to the requirements of UMRA sections 202, 203, 204, or 205 (2 U.S.C. 1501 
                    *et seq.*). E. Executive Order 13132: Federalism This action will not have federalism implications as specified in Executive Order 13132 (64 FR 43255, August 10, 1999), because it is not expected to have a substantial direct effect on States, on the relationship between the National Government and the States, or on the distribution of power and responsibilities among the various levels of government. F. Executive Order 13175: Consultation and Coordination With Indian Tribal Governments This action will not have Tribal implications as specified under Executive Order 13175 (65 FR 67249, November 9, 2000), because it is not expected to have substantial direct effects on Indian Tribes or significantly or uniquely affect the communities of Indian Tribal governments, and does not involve or impose any requirements that affect Indian Tribes. G. Executive Order 13045: Protection of Children From Environmental Health and Safety Risks This action is not subject to Executive Order 13045 (62 FR 19885, April 23, 1997), because this is not an economically significant regulatory action as defined by Executive Order 12866, and this action does not address environmental health or safety risks disproportionately affecting children. H. Executive Order 13211: Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use This action is not subject to Executive Order 13211 (66 FR 28355, May 22, 2001), because this action is not a significant regulatory action under Executive Order 12866. I. National Technology Transfer and Advancement Act (NTTAA) NTTAA section 12(d), 15 U.S.C. 272 note, does not apply to this action because this action does not involve any technical standards. J. Executive Order 12898: Federal Actions To Address Environmental Justice in Minority Populations and Low-Income Populations This action does not entail special considerations of environmental justice related issues as delineated by Executive Order 12898 (59 FR 7629, February 16, 1994). K. Congressional Review Act (CRA) Pursuant to the CRA, 5 U.S.C. 801 
                    *et seq.,*
                     EPA will submit a rule report containing this rule and other required information to each House of the Congress and to the Comptroller General of the United States. This action is not a “major rule” as defined by 5 U.S.C. 804(2). List of Subjects 40 CFR Part 9 Environmental protection
Reporting and recordkeeping requirements 40 CFR Part 721 Environmental protection
Chemicals
Hazardous substances
Reporting and recordkeeping requirements
 Dated: June 15, 2022. Tala Henry, Deputy Director, Office of Pollution Prevention and Toxics.
 Therefore, for the reasons stated in the preamble, 40 CFR chapter I is amended as follows: PART 9—OMB APPROVALS UNDER THE PAPERWORK REDUCTION ACT
 1.The authority citation for part 9 continues to read as follows: Authority:
                        7 U.S.C. 135 
                            *et seq.,*
                             136-136y; 15 U.S.C. 2001, 2003, 2005, 2006, 2601-2671; 21 U.S.C. 331j, 346a; 31 U.S.C. 9701; 33 U.S.C. 1251 
                            *et seq.,*
                             1311, 1313d, 1314, 1318, 1321, 1326, 1330, 1342, 1344, 1345 (d) and (e), 1361; E.O. 11735, 38 FR 21243, 3 CFR, 1971-1975 Comp. p. 973; 42 U.S.C. 241, 242b, 243, 246, 300f, 300g, 300g-1, 300g-2, 300g-3, 300g-4, 300g-5, 300g-6, 300j-1, 300j-2, 300j-3, 300j-4, 300j-9, 1857 
                            *et seq.,*
                             6901-6992k, 7401-7671q, 7542, 9601-9657, 11023, 11048. 2.In § 9.1, amend the table by adding entries for §§ 721.11384 through 721.11389, 721.11394 through 721.11400, 721.11404 through 721.11410, and 721.11411 in numerical order under the undesignated center heading “Significant New Uses of Chemical Substances” to read as follows: § 9.1 OMB
  
 40 CFR citation
OMB control No.*    *    *    *    ***Significant New Uses of Chemical Substances***    *    *    *    *721.11384
2070-0012721.11385
2070-0012721.11386
2070-0012721.11387
2070-0012721.11388
2070-0012721.11389
2070-0012*    *    *    *    *721.11394
2070-0012721.11395
2070-0012721.11396
2070-0012721.11397
2070-0012721.11398
2070-0012721.11399
2070-0012721.11400
2070-0012*    *    *    *    *721.11404
2070-0012721.11405
2070-0012721.11406
2070-0012721.11407
2070-0012721.11408
2070-0012721.11409
2070-0012*    *    *    *    *721.11411
2070-0012( print page 38004)*    *    *    *    *
 PART 721—SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES
 3.The authority citation for part 721 continues to read as follows: Authority:
                        15 U.S.C. 2604, 2607, and 2625(c). Subpart E—Significant New Uses for Specific Chemical Substances
 4.Add §§ 721.11384 through 721.11389, §§ 721.11394 through 721.11400, §§ 721.11404 through 721.11409, and § 721.11411 to read as follows: *****
                        721.11384
                        Organic acid, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted amine-disubstituted polypropylene glycol reaction products (generic).
                        721.11385
                        Phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2-(chloromethyl)oxirane and .alpha.-(2-oxiranylmethyl)-.omega.-(2-oxiranylmethoxy)poly[oxy(methyl-1,2-ethanediyl)], reaction products with disubstituted amine and disubstituted polypropylene glycol, organic acid salts (generic)
                        § 721.11386
                        Organic acid, 2-substituted-, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted amine-disubstituted polypropylene glycol reaction products (generic).
                        § 721.11387
                        Phenol, 4,4′-(1-methylethylidene)bis-, polymer with .alpha.-(2-substituted-methylethyl)-.omega.-(2-substituted-methylethoxy)poly[oxy(methyl-1,2-ethanediyl)], 2-(chloromethyl)oxirane and .alpha.-(2-oxiranylmethyl)-.omega.-(2-oxiranylmethoxy)poly[oxy(methyl-1,2-ethanediyl)], alkylphenyl ethers, reaction products with disubstituted amine, organic acid salts (generic).
                        § 721.11388
                        Organic acid, compds. with bisphenol A-epichlorohydrin-disubstituted polypropylene glycol-polypropylene glycol diglycidyl ether polymer alkylphenyl ethers-disubstituted amine reaction products (generic).
                        § 721.11389
                        Organic acid, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted polypropylene glycol reaction products (generic).
 
 § 721.11394
                        Phosphonic acid, dimethyl ester, polymer with alkyl diols (generic).
                        § 721.11395
                        1H-Imidazole, 1,2,4,5-tetramethyl-.
                        § 721.11396
                        1-Propanaminium, N,N′-(oxydi-2,1-ethanediyl)bis[3-chloro-2-hydroxy-N,N-dimethyl-, chloride (1:2).
                        § 721.11397
                        Fatty acid, polymer with alkanedioic acid dialkyl ester, hydroxyl alkyl substituted alkanediol, substituted carbomonocycle and alkylol substituted alkane (generic).
                        § 721.11398
                        2,5-Furandione, polymer with ethenylbenzene, 4-hydroxy-substituted butyl amide, polymers with epichlorohydrin and trimethylolpropane, sodium salts (generic)
                        § 721.11399
                        2,5-Furandione, polymer with ethenylbenzene, 4-hydroxy-substitutedbutyl [3-[2-[1-[[(substitutedphenyl)amino]carbonyl]-2-oxopropyl]diazenyl]phenyl]methyl amide, polymers with epichlorohydrin and trimethylolpropane, sodium salts (generic)
                        § 721.11400
                        Alkane, bis(alkoxymethyl)-dimethyl- (generic).
 
 § 721.11404
                        Butanedioic acid, 2-methylene-, polymer with 2-methyl-2-[(1-oxo-2-propen-1-yl)amino]-1-propanesulfonic acid, sodium zinc salt.
                        § 721.11405
                        Heteromonocycle, alkenoic 1:1 salt, polymer with .alpha.-(2-methyl-1-oxo-2-propen-1-yl)-.omega.-methoxypoly(oxy-1,2-ethanediyl) and methyl-alkenoic acid (generic).
                        § 721.11406
                        Substituted benzylic ether polyethylene glycol alkyl ether derivative (generic).
                        § 721.11407
                        Alkylmultiheteroatom, 2-functionalisedalkyl-2-hydroxyalkyl-, polymer with alkylheteroatom-multialkylfunctionalised carbomonocycleheteroatom and multiglycidylether difunctionalised polyalkylene glycol (generic).
                        § 721.11408
                        Benzenedicarboxylic acid, reaction products with isobenzofurandione and diethylene glycol (generic).
                        § 721.11409
                        Formaldehyde, polymer with N1-(2-aminoethyl)-alkanediamine, 5-amino-1,3,3-trimethylcyclohexanemethanamine, 2-(chloromethyl)oxirane, 4,4′-(1-methylethylidene)bis[phenol] and .alpha.-hydro-.omega.-hydroxypoly(oxy-1,2-ethanediyl) (generic).
 
 § 721.11411
                        1-Butanol, reaction products with 2-[(2-propen-1-yloxy)methyl]oxirane.
 
 § 721.11384
                        Organic acid, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted amine-disubstituted polypropylene glycol reaction products (generic).
 (a) 
                        *Chemical substance and significant new uses subject to reporting.*
                         (1) The chemical substance identified generically as organic acid, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted amine-disubstituted polypropylene glycol reaction products (PMN P-17-312) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                        *Industrial, commercial, and consumer activities.*
                         It is a significant new use to manufacture, process, or use the substance in a manner that results in the generation of a dust, mist, or aerosol. (ii) 
                        *Release to water.*
                         Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=78. When making the computation of estimated surface water concentrations calculation under § 721.91 for this substance, you may subtract 90% from the highest expected daily release if the substance is subject to primary and secondary wastewater treatment as defined in 40 CFR part 133. (b) 
                        *Specific requirements.*
                         The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                        *Recordkeeping.*
                         Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                        *Limitation or revocation of certain notification requirements.*
                         The provisions of § 721.185 apply to this section. § 721.11385
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as phenol, 4,4′-(1-methylethylidene)bis-, polymer with 2-(chloromethyl)oxirane and .alpha.-(2-oxiranylmethyl)-.omega.-(2-oxiranylmethoxy)poly[oxy(methyl-1,2-ethanediyl)], reaction products with disubstituted amine and disubstituted polypropylene glycol, organic acid salts (PMN P-17-313) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in a manner that results in the generation of a dust, mist, or aerosol. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=78.
                            ( print page 38005) (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11386
  (a) 
                            *Chemical substance and significant new uses subject to reporting.* (1) The chemical substance identified generically as organic acid, 2-substituted-, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted amine-disubstituted polypropylene glycol reaction products (PMN P-17-314) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in a manner that results in the generation of a dust, mist, or aerosol. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=78. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11387
  (a) 
                            *Chemical substance and significant new uses subject to reporting.* (1) The chemical substance identified generically as phenol, 4,4′-(1-methylethylidene)bis-, polymer with .alpha.-(2-substituted-methylethyl)-.omega.-(2-substituted-methylethoxy)poly[oxy(methyl-1,2-ethanediyl)], 2-(chloromethyl)oxirane and .alpha.-(2-oxiranylmethyl)-.omega.-(2-oxiranylmethoxy)poly[oxy(methyl-1,2-ethanediyl)], alkylphenyl ethers, reaction products with disubstituted amine, organic acid salts (PMN P-17-315) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in a manner that results in the generation of a dust, mist, or aerosol. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 78. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11388
  (a) 
                            *Chemical substance and significant new uses subject to reporting.* (1) The chemical substance identified generically as organic acid, compds. with bisphenol A-epichlorohydrin-disubstituted polypropylene glycol-polypropylene glycol diglycidyl ether polymer alkylphenyl ethers-disubstituted amine reaction products (PMN P-17-316) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in a manner that results in the generation of a dust, mist, or aerosol. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=78. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11389
  (a) 
                            *Chemical substance and significant new uses subject to reporting.* (1) The chemical substance identified generically as organic acid, compds. with bisphenol A-epichlorohydrin-polypropylene glycol diglycidyl ether polymer-disubstituted polypropylene glycol reaction products (PMN P-17-317) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in a manner that results in the generation of a dust, mist, or aerosol. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=78. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11394
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as phosphonic acid, dimethyl ester, polymer with alkyl diols (PMN P-18-9) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use 
                            ( print page 38006)
                            the substance in a manner that generates a dust, mist, or aerosol. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=300. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11395
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified as 1H-imidazole, 1,2,4,5-tetramethyl- (PMN P-18-11; CAS No. 1739-83-9) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(f) and (g). (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=7. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11396
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified as 1-propanaminium, N,N′-(oxydi-2,1-ethanediyl)bis[3-chloro-2-hydroxy-N,N-dimethyl-, chloride (1:2) (PMN P-18-170; CAS No. 96320-92-2) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposures. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=164. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11397
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as fatty acid, polymer with alkanedioic acid dialkyl ester, hydroxyl alkyl substituted alkanediol, substituted carbomonocycle and alkylol substituted alkane (PMN P-18-185) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (i) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11398
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as 2,5-furandione, polymer with ethenylbenzene, 4-hydroxy-substituted butyl amide, polymers with epichlorohydrin and trimethylolpropane, sodium salts (PMN P-18-190) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to use the substance other than as a pigment dispersing aid for pigments in inkjet printing inks. (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (i) are applicable to manufacturers and processors of these substances. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11399
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as 2,5-furandione, polymer with ethenylbenzene, 4-hydroxy-substitutedbutyl [3-[2-[1-[[(substitutedphenyl)amino]carbonyl]-2-oxopropyl]diazenyl]phenyl]methyl amide, polymers with epichlorohydrin and trimethylolpropane, sodium salts (PMN P-18-191) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to use the substance other than as a pigment dispersing aid for pigments in inkjet printing inks. (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (i) are applicable to manufacturers and processors of these substances. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11400
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as alkane, bis(alkoxymethyl)-dimethyl- (PMN P-18-223) is subject to reporting under 
                            ( print page 38007)
                            this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture the substance beyond the confidential annual production volume specified in the PMN. (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (i) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section. (3) 
                            *Determining whether a specific use is subject to this section.*
                             The provisions of § 721.1725(b)(1) apply to paragraph (a)(2)(i) of this section.
 § 721.11404
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified as butanedioic acid, 2-methylene-, polymer with 2-methyl-2-[(1-oxo-2-propen-1-yl)amino]-1-propanesulfonic acid, sodium zinc salt (PMN P-18-285; CAS No. 2220235-78-7) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Releases to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=143. (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11405
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as heteromonocycle, alkenoic 1:1 salt, polymer with .alpha.-(2-methyl-1-oxo-2-propen-1-yl)-.omega.-methoxypoly(oxy-1,2-ethanediyl) and methyl-alkenoic acid (PMN P-18-300) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in a manner that results in particles less than 50 microns. It is a significant new use to use the substance in a manner that results in consumer inhalation or dermal exposure. It is a significant new use to use the substance other than as sealed single-use packets. (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (i) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11406
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as substituted benzylic ether polyethylene glycol alkyl ether derivative (PMN P-18-394) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(y)(1). (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=4. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11407
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as alkylmultiheteroatom, 2-functionalisedalkyl-2-hydroxyalkyl-, polymer with alkylheteroatom-multialkylfunctionalised carbomonocycleheteroatom and multiglycidylether difunctionalised polyalkylene glycol (PMN P-18-404) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11408
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as benzenedicarboxylic acid, reaction products with isobenzofurandione and diethylene glycol (PMN P-19-12) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part 
                            ( print page 38008)
                            apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), and (i) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11409
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as formaldehyde, polymer with N1-(2-aminoethyl)-alkanediamine, 5-amino-1,3,3-trimethylcyclohexanemethanamine, 2-(chloromethyl)oxirane, 4,4′-(1-methylethylidene)bis[phenol] and .alpha.-hydro-.omega.-hydroxypoly(oxy-1,2-ethanediyl) (PMN P-19-31) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (ii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=1. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c), (i), and (k) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11411
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified as 1-butanol, reaction products with 2-[(2-propen-1-yloxy)methyl]oxirane (PMN P-19-72) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(j). (ii) [Reserved] (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (c) and (i) are applicable to manufacturers and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section. (3) 
                            *Determining whether a specific use is subject to this section.*
                             The provisions of § 721.1725(b)(1) apply to paragraph (a)(2)(i) of this section.


[FR Doc. 2022-13338 Filed 6-24-22; 8:45 am] BILLING CODE 6560-50-P