**Exhibit4.1**

**HOSPIRA, INC.**

**Floating Rate Note due2010**
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**CUSIP No.**441060 AG5

This Security is aSecurity in a global form within the meaning of the Indenture hereinafterreferred to and is registered in the name of the Depository or a nominee of theDepository.  This global Security isexchangeable for Securities registered in the name of a Person other than theDepository or its nominee only in the limited circumstances described in theIndenture, and no transfer of this Security (other than a transfer of thisSecurity as a whole by the Depository to a nominee of the Depository or by anominee of the Depository to the Depository or another nominee of theDepository) may be registered except in such limited circumstances.

Unless thisSecurity is presented by an authorized representative of The Depository TrustCompany (55 Water Street, New York, New York) to the issuer or its agent forregistration of transfer, exchange or payment, and any Security issued uponregistration of transfer of, or in exchange for, or in lieu of, this Securityis registered in the name of Cede & Co. or such other name as requested byan authorized representative of The Depository Trust Company and any paymenthereon is made to Cede & Co., ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FORVALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL since the registered ownerhereof, Cede & Co., has an interest herein.

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**HOSPIRA,INC.**

HOSPIRA, INC., a corporation duly organized andexisting under the laws of Delaware (herein called the “Company,” which termincludes any successor Person under the Indenture hereinafter referred to), forvalue received, hereby promises to pay to Cede & Co., as nominee for TheDepository Trust Company, or registered assigns, the principal sum of ThreeHundred Seventy Five Million Dollars ($375,000,000) on March 30, 2010 and topay interest thereon from March 23, 2007 or from the most recent March 30, June30, September 30, or December 30 (each an “Interest Payment Date”) to whichinterest has been paid or duly provided for, quarterly on each Interest PaymentDate in each year, commencing June 30, 2007, at the rate of three-month LIBOR(as defined below) plus 48 basis points per annum, until the principal hereofis paid or made available for payment. The interest so payable, and punctually paid or duly provided for, onany Interest Payment Date will, as provided in such Indenture, be paid to thePerson in whose name this Security (or one or more predecessor Securities) isregistered at the close of business on the March 15, June 15, September 15, orDecember 15 (whether or not a business day, as defined below) (each a “RegularRecord Date”), as the case may be, next preceding such Interest PaymentDate.  Any such interest not sopunctually paid or duly provided for (the “defaulted interest”) will forthwithcease to be payable to the holder on such Regular Record Date and may either bepaid to the Person in whose name this Security (or one or more predecessorSecurities) is registered at the close of business on a date for the payment ofdefaulted interest to be fixed by the Trustee (the “Special Record Date”),notice whereof shall be given to holders of Securities of this series not lessthan 10 days prior to such Special Record Date, or be paid at any time in anyother lawful manner not inconsistent with the requirements of any securitiesexchange on which the Securities of this series may be listed, and upon suchnotice as may be requiredby such exchange, all as more fully provided in said Indenture.

The interest rate on the Securities will be reset onthe first day of each interest period other than the initial interest period(each an “Interest Reset Date”).  Aninterest period is the period commencing on an Interest Payment Date (or, inthe case of the initial interest period, commencing on the date the Securitiesare issued) and ending on the day preceding the next following Interest PaymentDate; the initial interest period is March 23, 2007 through June 29, 2007. TheInterest Reset Dates are March 30, June 30, September 30 and**December 30 of each year, beginningJune 30, 2007. The Interest Determination Date for an interest period will bethe second London banking day (as defined below) preceding such interest period(the “Interest Determination Date”). The Interest Determination Date for theinitial interest period will be March 21, 2007. Promptly upon determination, the trustee will inform the Companyof the interest rate for the next interest period.  Interest on the Securities will be calculatedon the basis of the actual number of days in an interest period and a 360-dayyear.

If any Interest Payment Date, other than the maturitydate, falls on a day that is not a business day, the Interest Payment Date willbe postponed to the next day that is a business day, except if that businessday is in the next succeeding calendar month, the Interest Payment Date will bethe immediately preceding business day. If the maturity date of the Securityfalls on a day that is not a business day, the payment of interest andprincipal will be made on the next succeeding business day, and no interest onsuch payment will accrue for the period from and after the maturity date. Asused herein, “business day” means any day, other than a Saturday or 

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Sunday, that is neither alegal holiday nor a day on which banking institutions are authorized orrequired by law or regulations to close in New York, New York or Luxembourg.

“LIBOR” for each Interest Determination Date will bedetermined by the calculation agent as follows:

(i)    If this rate does not appear onPage LIBOR01, the calculation agent will determine the rate on the basisof the rates at which deposits in U.S. dollars are offered by four majorbanks in the London interbank market (selected by the calculation agent afterconsulting with the Company) at approximately 11:00 a.m., London time, onthe Interest Determination Date for the applicable Interest Reset Date to primebanks in the London interbank market for a period of three months commencing onthat Interest Reset Date and in principal amount equal to an amount not lessthan $1,000,000 that is representative for a single transaction in such marketat such time. In such case, the calculation agent will request the principalLondon office of each of these major banks to provide a quotation of such rate.If at least two such quotations are provided, LIBOR will be the arithmeticaverage of the quotations. If fewer than two quotations are provided asrequested, LIBOR for that Interest Determination Date will be the arithmeticaverage of the rates quoted by three major banks in New York, New York(selected by the calculation agent after consulting with the Company) atapproximately 11:00 a.m., New York time, on the Interest Determination Datefor the applicable Interest Determination Date for loans in U.S. dollarsto leading European banks for a period of three months commencing on thatInterest Reset Date and in a principal amount equal to an amount not less than$1,000,000 that is representative for a single transaction in such market atsuch time. If fewer than three quotations are provided as requested, for theperiod until the next Interest Reset Date, LIBOR will be the same as the ratedetermined for the immediately preceding Interest Reset Date.

(ii)   LIBOR will be equal to the offeredrate for deposits in U.S. dollars having an index maturity of threemonths, in amounts of at least $1,000,000 as such rate appears onPage LIBOR01 at approximately 11:00 a.m., London time, on theInterest Determination Date for the applicable Interest Reset Date. “Page LIBOR01”means the display page so designated on the Reuters Money 3000 Xtraservice for the purpose of displaying London interbank offered rates of majorbanks, or any successor page on the Reuters Money 3000 Xtra service.

A “London banking day” will be any day in whichdealings in U.S. dollar deposits are transacted in the London interbankmarket.

The calculation agent will provide the interest ratethen in effect upon any change to the holder of any Security and to theCompany. The calculation agent is LaSalle Bank National Association until suchtime as the Company appoints a successor calculation agent. All calculationsmade by the calculation agent in the absence of willful misconduct, bad faithor manifest error shall be conclusive for all purposes and binding on theCompany and the holders of the Securities. The Company may appoint a successorcalculation agent at any time at the Company’s discretion and without notice.

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All percentages used in or resulting from anycalculation of the interest rate with respect to the Securities will berounded, if necessary, to the nearest one-hundred thousandth of a percentagepoint, with five one-millionth of a percentage point rounded upward (e.g., 9.876545%(or .09876545) would be rounded to 9.87655% (or .0987655) and 9.876544% (or..09876544) would be rounded to 9.87654% (or .0987654)), and all U.S. dollaramounts used in or resulting from any such calculation will be rounded to thenearest cent (with one-half cent being rounded upward).

Payment of the principal of (and premium, if any) andany such interest on this Security will be made at the office or agency of theCompany maintained for that purpose in Chicago, Illinois, in such coin orcurrency of the United States of America as at the time of payment is legaltender for payment of public and private debts; provided, however,that at the option of the Company payment of interest may be made by checkmailed to the address of the Person entitled thereto as such address shallappear in the Security Register.

Reference is hereby made to the further provisions ofthis Security set forth on the reverse hereof, which further provisions shallfor all purposes have the same effect as if set forth at this place.

Unless the certificate of authentication hereon hasbeen executed by the Trustee referred to herein by manual signature, thisSecurity shall not be entitled to any benefit under the Indenture or be validor obligatory for any purpose.

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INWITNESS WHEREOF, the Company has caused this instrument to be duly executedunder its corporate seal.
| Dated: March 23, 2007 |          |
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|                  | HOSPIRA, INC. |
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TRUSTEE’S CERTIFICATE OF AUTHENTICATION

This is one of the Securities designated thereinreferred to in the within-mentioned Indenture.

 
|   | LASALLE BANK NATIONAL  ASSOCIATION,  as Trustee |
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|   | By                                              |   |
|   |                                            | Name: |
|   |                                            | Title: |

 

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This Security is one of aduly authorized issue of securities of the Company (herein called the “Securities”),issued and to be issued in one or more series under an Indenture, dated as ofJune 14 , 2004 (herein called the “Indenture”) between the Company and LaSalleBank National Association, as Trustee (herein called the “Trustee,” which termincludes any successor trustee under the Indenture), to which Indenturereference is hereby made for a statement of the respective rights, limitationsof rights, duties and immunities thereunder of the Company, the Trustee and theholders of the Securities and of the terms upon which the Securities are, andare to be, authenticated and delivered. This Security is one of the series designated on the face hereof,limited in aggregate principal amount to $375,000,000.

The Company may redeem the Securities of this series, as a whole or in part, at its option,at any time after one year from the date of issuance at 100% of the principalamount

If the Company has given notice as provided in theIndenture and funds for the redemption of any Securities of this series calledfor redemption have been made available on the redemption date, such Securitieswill cease to bear interest on the date fixed for redemption.  Thereafter, the only right of the holders ofsuch Securities will be to receive payment of the redemption price.

The Company will prepare and mail a notice ofredemption to each holder of Securities to be redeemed by first-class mail atleast 30 and not more than 60 calendar days prior to the date fixed for redemption.On and after a redemption date, interest will cease to accrue on the Securitiescalled for redemption (unless the Company defaults in the payment of theredemption price and accrued interest). On or before a redemption date, theCompany will deposit with a paying agent (or the trustee) money sufficient topay the redemption price of and accrued interest on the Securities to beredeemed on that date. If less than all of the Securities of a series are to beredeemed, the Securities to be redeemed shall be selected by the trustee prorata or by lot or by a method the trustee deems to be fair and appropriate.

The Company will notify the Trustee at least 45 daysprior to giving notice of redemption (or such shorter period as is satisfactoryto the Trustee) of the aggregate principal amount of the Securities of thisseries to be redeemed and their redemption date.  If less than all of the Securities of thisseries are to be redeemed, the Trustee shall select which Securities are to be redeemed in a manner it deems to be fair andappropriate.

TheSecurities of this series do not provide for a sinking fund.

If a Change of Control Triggering Event (as definedbelow) occurs, unless the Company has exercised its right to redeem theSecurities as described above, holders of Securities will have the right torequire the Company to repurchase all or any part (equal to $2,000 or anintegral multiple of $1,000 in excess thereof) of their Securities pursuant tothe offer described below (the “Change of Control Offer”). In the Change ofControl Offer, the Company will be required to offer payment in cash equal to101% of the aggregate principal amount of Securities repurchased plus accruedand unpaid interest, if any, on the Securities repurchased, to the date ofpurchase (the “Change of Control Payment”). Within 30 days following any Changeof Control Triggering Event, the Company will be required to mail a notice toholders of Securities describing the transaction or transactions thatconstitute the Change of Control Triggering Event 

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andoffering to repurchase the Securities on the date specified in the notice,which date will be no earlier than 30 days and no later than 60 days from thedate such notice is mailed (the “Change of Control Payment Date”), pursuant tothe procedures required by the Securities and described in such notice. TheCompany must comply with the requirements of Rule 14e-1 under the SecuritiesExchange Act of 1934, as amended (the “Exchange Act”) and any other securitieslaws and regulations thereunder to the extent those laws and regulations areapplicable in connection with the repurchase of the Securities as a result of aChange of Control Triggering Event. To the extent that the provisions of anysecurities laws or regulations conflict with the Change of Control provisionsof the Securities, the Company will be required to comply with the applicablesecurities laws and regulations and will not be deemed to have breached itsobligations under the Change of Control provisions of the Securities by virtueof such conflicts.

On the Change of Control Payment Date, the Companywill be required, to the extent lawful, to:

·                  accept forpayment all Securities or portions of Securities properly tendered pursuant tothe Change of Control Offer;

·                  deposit with thepaying agent an amount equal to the Change of Control Payment in respect of allSecurities or portions of Securities properly tendered; and

·                  deliver or causeto be delivered to the Trustee the Securities properly accepted.

For purposes of the foregoing discussion of arepurchase at the option of holders, the following definitions are applicable:

“Below Investment Grade Rating Event” means theSecurities are rated below an Investment Grade Rating by each of the RatingAgencies (as defined below) on any date from the date of the public notice ofan arrangement that could result in a Change of Control until the end of the60-day period following public notice of the occurrence of the Change ofControl (which 60-day period shall be extended so long as the rating of theSecurities is under publicly announced consideration for possible downgrade byeither of the Rating Agencies).

“Change of Control” means the occurrence of any of thefollowing: (1) the direct or indirect sale, transfer, conveyance or otherdisposition (other than by way of merger or consolidation), in one or a seriesof related transactions, of all or substantially all of the properties orassets of the Company and its subsidiaries taken as a whole to any person (assuch term is used in Section 13(d) of the Exchange Act) other than the Companyor one of its subsidiaries; (2) the consummation of any transaction(including, without limitation, any merger or consolidation) the result ofwhich is that any person (as such term is used in Section 13(d) of the ExchangeAct) becomes the beneficial owner, directly or indirectly, of more than 50% ofthe then outstanding number of shares of the Company’s voting stock; or(3) the first day on which a majority of the members of the Company’sBoard of Directors are not Continuing Directors.

“Change of Control Triggering Event” means theoccurrence of both a Change of Control and a Below Investment Grade RatingEvent.

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“Continuing Directors” means, as of any date ofdetermination, any member of the Company who (1) was a member of suchBoard of Directors on the date of the issuance of the Securities; or(2) was nominated for election or elected to such Board of Directors withthe approval of a majority of the Continuing Directors who were members of suchBoard of Directors at the time of such nomination or election (either by aspecific vote or by approval of the Company’s proxy statement in which suchmember was named as a nominee for election as a director, without objection tosuch nomination).

“Investment Grade Rating” means a rating equal to orhigher than Baa3 (or the equivalent) by Moody’s and BBB- (or the equivalent) byS&P.

“Moody’s” means Moody’s Investors Service, Inc.

 “RatingAgencies” means (1) each of Moody’s and S&P; and (2) if either ofMoody’s or S&P ceases to rate the Securities or fails to make a rating ofthe Securities publicly available for reasons outside of the Company’s control,a “nationally recognized statistical rating organization” within the meaning ofRule 15c3-1(c)(2)(vi)(F) under the Exchange Act, selected by the Company (ascertified by a resolution of the Company’s Board of Directors) as a replacementagency for Moody’s or S&P, or both of them, as the case may be.

“S&P” means Standard & Poor’s RatingsServices, a division of The McGraw-Hill Companies, Inc.

If an Event of Default with respect to Securities ofthis series shall occur and be continuing, the principal of the Securities ofthis series may be declared due and payable in the manner and with the effectprovided in the Indenture.

The Indenture contains provisions for defeasance atany time of the entire indebtedness of this Security or certain restrictivecovenants and Events of Default with respect to this Security, in each caseupon compliance with certain conditions set forth therein.

The Indenture permits, with certain exceptions astherein provided, the amendment thereof and the modification of the rights andobligations of the Company and the rights of the holders of the Securities ofeach series to be affected under the Indenture at any time by the Company andthe Trustee with the consent of the holders of a majority in principal amountof the Securities at the time Outstanding of each series to be affected.  The Indenture also contains provisionspermitting the holders of specified percentages in principal amount of theSecurities of each series at the time Outstanding, on behalf of the holders ofall Securities of such series, to waive compliance by the Company with certainprovisions of the Indenture and certain past defaults under the Indenture andtheir consequences.  Any such consent orwaiver by the holder of this Security shall be conclusive and binding upon suchholder and upon all future holders of this Security and of any Security issuedupon the registration of transfer hereof or in exchange herefor or in lieuhereof, whether or not notation of such consent or waiver is made upon thisSecurity.

No reference herein to the Indenture and no provisionof this Security or of the Indenture shall alter or impair the obligation ofthe Company, which is absolute and unconditional, to pay 

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the principal of and anypremium and interest on this Security at the times, place and rate, and in thecoin or currency, herein prescribed.

As provided in the Indenture and subject to certainlimitations therein set forth, the transfer of this Security is registerable inthe Security Register, upon surrender of this Security for registration oftransfer at the office or agency of the Company in any place where theprincipal of and any premium and interest on this Security are payable, dulyendorsed by, or accompanied by a written instrument of transfer in formsatisfactory to the Company and the Security Registrar duly executed by, theholder hereof or his attorney duly authorized in writing, and thereupon one ormore new Securities of this series and of like tenor, of authorizeddenominations and for the same aggregate principal amount, will be issued tothe designated transferee or transferees.

The Securities of this series are issuable only inregistered form without coupons in denominations of $2,000 and integralmultiples of $1,000.  As provided in theIndenture and subject to certain limitations therein set forth, Securities ofthis series are exchangeable for a like aggregate principal amount ofSecurities of this series and of like tenor of a different authorizeddenomination, as requested by the holder surrendering the same.

No service charge shall be made for any suchregistration of transfer or exchange, but the Company may require payment of asum sufficient to cover any tax or other governmental charge payable inconnection therewith.

Prior to due presentment of this Security forregistration of transfer, the Company, the Trustee and any agent of the Companyor the Trustee may treat the Person in whose name this Security is registeredas the owner hereof for all purposes, whether or not this Security be overdue,and neither the Company, the Trustee nor any such agent shall be affected bynotice to the contrary.

Allterms used in this Security which are defined in the Indenture shall have themeanings assigned to them in the Indenture.

ThisSecurity is a Book-Entry Security within the meaning of the Indenturehereinafter referred to and is registered in the name of a Depository or anominee of a Depository.  This Securityis exchangeable for Securities registered in the name of a person other thanthe Depository or its nominee only in the limited circumstances described inthe Indenture and may not be transferred except as a whole by the Depository toa nominee of the Depository or by a nominee of the Depository to the Depositoryor another nominee of the Depository.

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