**Exhibit4.2**

**HOSPIRA, INC.**

**5.55% Note due 2012**
| **No. 1** | ** ** | **$                    ** |
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**CUSIP No. 441060 AH3**

This Security is aSecurity in a global form within the meaning of the Indenture hereinafterreferred to and is registered in the name of the Depository or a nominee of theDepository.  This global Security isexchangeable for Securities registered in the name of a Person other than theDepository or its nominee only in the limited circumstances described in theIndenture, and no transfer of this Security (other than a transfer of thisSecurity as a whole by the Depository to a nominee of the Depository or by anominee of the Depository to the Depository or another nominee of theDepository) may be registered except in such limited circumstances.

Unless thisSecurity is presented by an authorized representative of The Depository TrustCompany (55 Water Street, New York, New York) to the issuer or its agent forregistration of transfer, exchange or payment, and any Security issued uponregistration of transfer of, or in exchange for, or in lieu of, this Securityis registered in the name of Cede & Co. or such other name as requested byan authorized representative of The Depository Trust Company and any paymenthereon is made to Cede & Co., ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FORVALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL since the registered ownerhereof, Cede & Co., has an interest herein.

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**HOSPIRA,INC.**

HOSPIRA, INC., a corporation duly organized andexisting under the laws of Delaware (herein called the “Company,” which termincludes any successor Person under the Indenture hereinafter referred to), forvalue received, hereby promises to pay to Cede & Co., as nominee for TheDepository Trust Company, or registered assigns, the principal sum of FiveHundred Million Dollars ($500,000,000) on March 30, 2012 and to pay interestthereon from March 23, 2007 or from the most recent Interest Payment Date towhich interest has been paid or duly provided for, semi-annually on March 30and September 30 in each year, commencing September 30, 2007, at the rateof  5.55% per annum, until the principalhereof is paid or made available for payment. The interest so payable, and punctually paid or duly provided for, onany Interest Payment Date will, as provided in such Indenture, be paid to thePerson in whose name this Security (or one or more Predecessor Securities) isregistered at the close of business on the Regular Record Date for suchinterest, which shall be the March 15 or September 15 (whether or not aBusiness Day), as the case may be, next preceding such Interest PaymentDate.  Any such interest not sopunctually paid or duly provided for will forthwith cease to be payable to theHolder on such Regular Record Date and may either be paid to the Person inwhose name this Security (or one or more Predecessor Securities) is registeredat the close of business on a Special Record Date for the payment of suchDefaulted Interest to be fixed by the Trustee, notice whereof shall be given toHolders of Securities of this series not less than 10 days prior to suchSpecial Record Date, or be paid at any time in any other lawful manner notinconsistent with the requirements of any securities exchange on which theSecurities of this series may be listed, and upon such notice as may berequired by such exchange, all as more fully provided in said Indenture.

Payment of the principal of (and premium, if any) andany such interest on this Security will be made at the office or agency of theCompany maintained for that purpose in Chicago, Illinois, in such coin orcurrency of the United States of America as at the time of payment is legaltender for payment of public and private debts; provided, however,that at the option of the Company payment of interest may be made by checkmailed to the address of the Person entitled thereto as such address shallappear in the Security Register.

Reference is hereby made to the further provisions ofthis Security set forth on the reverse hereof, which further provisions shallfor all purposes have the same effect as if set forth at this place.

Unless the certificate of authentication hereon hasbeen executed by the Trustee referred to herein by manual signature, thisSecurity shall not be entitled to any benefit under the Indenture or be validor obligatory for any purpose.

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INWITNESS WHEREOF, the Company has caused this instrument to be duly executedunder its corporate seal.

Dated: March 23,2007
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TRUSTEE’S CERTIFICATE OF AUTHENTICATION

This is one of the Securities designated thereinreferred to in the within-mentioned Indenture.
|   | LASALLE BANK NATIONAL  ASSOCIATION,  as Trustee |
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|   | By                                              |   |
|   |                                            | Name: |
|   |                                            | Title: |

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This Security is one of a duly authorized issue ofsecurities of the Company (herein called the “Securities”), issued and to beissued in one or more series under an Indenture, dated as of June 14 , 2004(herein called the “Indenture”) between the Company and LaSalle Bank NationalAssociation, as Trustee (herein called the “Trustee,” which term includes anysuccessor trustee under the Indenture), to which Indenture reference is herebymade for a statement of the respective rights, limitations of rights, dutiesand immunities thereunder of the Company, the Trustee and the Holders of theSecurities and of the terms upon which the Securities are, and are to be,authenticated and delivered.  ThisSecurity is one of the series designated on the face hereof, limited inaggregate principal amount to $500,000,000.

The Company may redeem the Securities of this series,in whole at any time, or in part from time to time, at the Company’s option, onnot less than 30 nor more than 60 days’ notice, subject to the payment ofa redemption price equal to the greater of (1) 100% of the principalamount of the Securities to be redeemed and (2) the sum of the presentvalues of the Remaining Scheduled Payments (as defined below) on such Securitiesdiscounted to the date of redemption, on a semi-annual basis (assuming a360-day year consisting of twelve 30-day months), at a rate equal to the sum of the applicableTreasury Rate (as defined below), plus 20 basis points.   In each case, accrued and unpaid interestwill also be paid to but excluding the redemption date.

If the Company has given notice as provided in theIndenture and funds for the redemption of any Securities of this series calledfor redemption have been made available on the redemption date, such Securitieswill cease to bear interest on the date fixed for redemption.  Thereafter, the only right of the Holders ofsuch Securities will be to receive payment of the redemption price.

The Company will prepare and mail a notice ofredemption to each holder of Securities to be redeemed by first-class mail atleast 30 and not more than 60 calendar days prior to the date fixed forredemption. On and after a redemption date, interest will cease to accrue onthe Securities called for redemption (unless the Company defaults in thepayment of the redemption price and accrued interest). On or before aredemption date, the Company will deposit with a paying agent (or the trustee)money sufficient to pay the redemption price of and accrued interest on the Securitiesto be redeemed on that date. If less than all of the Securities of a series areto be redeemed, the Securities to be redeemed shall be selected by the trusteepro rata or by lot or by a method the trustee deems to be fair and appropriate.

The Company will notify the Trustee at least 45 daysprior to giving notice of redemption (or such shorter period as is satisfactoryto the Trustee) of the aggregate principal amount of the Securities of thisseries to be redeemed and their redemption date.  If less than all of the Securities of thisseries are to be redeemed, the Trustee shall select which Securities are to be redeemed in a manner it deems to be fair andappropriate.

“Comparable Treasury Issue” means the United StatesTreasury security selected by a Reference Treasury Dealer (as defined below) ashaving an actual or interpolated maturity comparable to the remaining term ofthe Securities called for redemption, that would be utilized, at the time ofselection and in accordance with customary financial practice, in pricing newissues of corporate debt securities of comparable maturity to the remainingterm of Securities called for redemption.

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“Comparable Treasury Price” means, with respect to anyredemption date, (1) the average of three Reference Treasury Dealer Quotationsfor such redemption date, after excluding the highest and lowest ReferenceTreasury Dealer Quotations, or (2) if the calculation agent obtains fewer thanthree such Reference Treasury Dealer Quotations, the average of all such quotations.

“Reference Treasury Dealer” means MorganStanley & Co. Incorporated, ABN AMRO Incorporated, Citigroup GlobalMarkets Inc., and two other primary U.S. Government securities dealers selectedby the Company, and each of their respective successors. If any of theforegoing shall cease to be a primary U.S. Government securities dealer, theCompany will substitute another nationally recognized investment banking firmthat is a primary U.S. Government securities dealer.

“Reference Treasury Dealer Quotations” means, on anyredemption date, the average, as determined by the calculation agent, of thebid and asked prices for the Comparable Treasury Issue (expressed in each caseas a percentage of its principal amount) quoted in writing to the Company byeach Reference Treasury Dealer at 3:30 p.m., New York City time, on the thirdbusiness day preceding that redemption date.

“Remaining Scheduled Payments” means the remainingscheduled payments of principal of and interest on the Securities called forredemption that would be due after the related redemption date but for thatredemption. If that redemption date is not an interest payment date withrespect to the Securities called for redemption, the amount of the nextsucceeding scheduled interest payment on such Securities will be reduced by theamount of interest accrued on the Securities called for redemption to suchredemption date.

“Treasury Rate” means, with respect to any redemptiondate, the rate per annum equal to the semi-annual equivalent yield to maturity(computed as of the third business day immediately preceding that redemptiondate) of the Comparable Treasury Issue, assuming a price for the ComparableTreasury Issue (expressed as a percentage of its principal amount) equal to theComparable Treasury Price for that redemption date.

TheSecurities of this series do not provide for a sinking fund.

If a Change of Control Triggering Event (as definedbelow) occurs, unless the Company has exercised its right to redeem theSecurities as described above, holders of Securities will have the right torequire the Company to repurchase all or any part (equal to $2,000 or anintegral multiple of $1,000 in excess thereof) of their Securities pursuant tothe offer described below (the “Change of Control Offer”). In the Change ofControl Offer, the Company will be required to offer payment in cash equal to101% of the aggregate principal amount of Securities repurchased plus accruedand unpaid interest, if any, on the Securities repurchased, to the date ofpurchase (the “Change of Control Payment”). Within 30 days following any Changeof Control Triggering Event, the Company will be required to mail a notice toholders of Securities describing the transaction or transactions thatconstitute the Change of Control Triggering Event and offering to repurchasethe Securities on the date specified in the notice, which date will be noearlier than 30 days and no later than 60 days from the date such notice ismailed (the “Change of Control Payment Date”), pursuant to the proceduresrequired by the Securities and described in such notice. The Company mustcomply with the requirements of Rule 14e-1 under the 

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SecuritiesExchange Act of 1934, as amended (the “Exchange Act”) and any other securitieslaws and regulations thereunder to the extent those laws and regulations areapplicable in connection with the repurchase of the Securities as a result of aChange of Control Triggering Event. To the extent that the provisions of anysecurities laws or regulations conflict with the Change of Control provisionsof the Securities, the Company will be required to comply with the applicablesecurities laws and regulations and will not be deemed to have breached itsobligations under the Change of Control provisions of the Securities by virtue ofsuch conflicts.

On the Change of Control Payment Date, the Companywill be required, to the extent lawful, to:

·                  accept forpayment all Securities or portions of Securities properly tendered pursuant tothe Change of Control Offer;

·                  deposit with thepaying agent an amount equal to the Change of Control Payment in respect of allSecurities or portions of Securities properly tendered; and

·                  deliver or causeto be delivered to the Trustee the Securities properly accepted.

For purposes of the foregoing discussion of arepurchase at the option of holders, the following definitions are applicable:

“Below Investment Grade Rating Event” means theSecurities are rated below an Investment Grade Rating by each of the RatingAgencies (as defined below) on any date from the date of the public notice ofan arrangement that could result in a Change of Control until the end of the60-day period following public notice of the occurrence of the Change ofControl (which 60-day period shall be extended so long as the rating of theSecurities is under publicly announced consideration for possible downgrade byeither of the Rating Agencies).

“Change of Control” means the occurrence of any of thefollowing: (1) the direct or indirect sale, transfer, conveyance or otherdisposition (other than by way of merger or consolidation), in one or a seriesof related transactions, of all or substantially all of the properties orassets of the Company and its subsidiaries taken as a whole to any person (assuch term is used in Section 13(d) of the Exchange Act) other than the Companyor one of its subsidiaries; (2) the consummation of any transaction(including, without limitation, any merger or consolidation) the result ofwhich is that any person (as such term is used in Section 13(d) of the ExchangeAct) becomes the beneficial owner, directly or indirectly, of more than 50% ofthe then outstanding number of shares of the Company’s voting stock; or(3) the first day on which a majority of the members of the Company’sBoard of Directors are not Continuing Directors.

“Change of Control Triggering Event” means theoccurrence of both a Change of Control and a Below Investment Grade RatingEvent.

“Continuing Directors” means, as of any date ofdetermination, any member of the Company who (1) was a member of suchBoard of Directors on the date of the issuance of the Securities; or(2) was nominated for election or elected to such Board of Directors withthe 

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approvalof a majority of the Continuing Directors who were members of such Board ofDirectors at the time of such nomination or election (either by a specific voteor by approval of the Company’s proxy statement in which such member was namedas a nominee for election as a director, without objection to such nomination).

“Investment Grade Rating” means a rating equal to orhigher than Baa3 (or the equivalent) by Moody’s and BBB- (or the equivalent) byS&P.

“Moody’s” means Moody’s Investors Service, Inc.

 “RatingAgencies” means (1) each of Moody’s and S&P; and (2) if either ofMoody’s or S&P ceases to rate the Securities or fails to make a rating ofthe Securities publicly available for reasons outside of the Company’s control,a “nationally recognized statistical rating organization” within the meaning ofRule 15c3-1(c)(2)(vi)(F) under the Exchange Act, selected by the Company (ascertified by a resolution of the Company’s Board of Directors) as a replacementagency for Moody’s or S&P, or both of them, as the case may be.

“S&P” means Standard & Poor’s RatingsServices, a division of The McGraw-Hill Companies, Inc.

If an Event of Default with respect to Securities ofthis series shall occur and be continuing, the principal of the Securities ofthis series may be declared due and payable in the manner and with the effectprovided in the Indenture.

The Indenture contains provisions for defeasance atany time of the entire indebtedness of this Security or certain restrictivecovenants and Events of Default with respect to this Security, in each caseupon compliance with certain conditions set forth therein.

The Indenture permits, with certain exceptions astherein provided, the amendment thereof and the modification of the rights andobligations of the Company and the rights of the Holders of the Securities ofeach series to be affected under the Indenture at any time by the Company andthe Trustee with the consent of the Holders of a majority in principal amountof the Securities at the time Outstanding of each series to be affected.  The Indenture also contains provisionspermitting the Holders of specified percentages in principal amount of theSecurities of each series at the time Outstanding, on behalf of the Holders ofall Securities of such series, to waive compliance by the Company with certainprovisions of the Indenture and certain past defaults under the Indenture andtheir consequences.  Any such consent orwaiver by the Holder of this Security shall be conclusive and binding upon suchHolder and upon all future Holders of this Security and of any Security issuedupon the registration of transfer hereof or in exchange herefor or in lieuhereof, whether or not notation of such consent or waiver is made upon thisSecurity.

No reference herein to the Indenture and no provisionof this Security or of the Indenture shall alter or impair the obligation ofthe Company, which is absolute and unconditional, to pay the principal of andany premium and interest on this Security at the times, place and rate, and inthe coin or currency, herein prescribed.

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As provided in the Indenture and subject to certainlimitations therein set forth, the transfer of this Security is registerable inthe Security Register, upon surrender of this Security for registration oftransfer at the office or agency of the Company in any place where theprincipal of and any premium and interest on this Security are payable, dulyendorsed by, or accompanied by a written instrument of transfer in formsatisfactory to the Company and the Security Registrar duly executed by, theHolder hereof or his attorney duly authorized in writing, and thereupon one ormore new Securities of this series and of like tenor, of authorizeddenominations and for the same aggregate principal amount, will be issued tothe designated transferee or transferees.

The Securities of this series are issuable only inregistered form without coupons in denominations of $2,000 and integralmultiples of $1,000.  As provided in theIndenture and subject to certain limitations therein set forth, Securities ofthis series are exchangeable for a like aggregate principal amount ofSecurities of this series and of like tenor of a different authorizeddenomination, as requested by the Holder surrendering the same.

No service charge shall be made for any suchregistration of transfer or exchange, but the Company may require payment of asum sufficient to cover any tax or other governmental charge payable inconnection therewith.

Prior to due presentment of this Security forregistration of transfer, the Company, the Trustee and any agent of the Companyor the Trustee may treat the Person in whose name this Security is registeredas the owner hereof for all purposes, whether or not this Security be overdue,and neither the Company, the Trustee nor any such agent shall be affected bynotice to the contrary.

Allterms used in this Security which are defined in the Indenture shall have themeanings assigned to them in the Indenture.

ThisSecurity is a Book-Entry Security within the meaning of the Indenturehereinafter referred to and is registered in the name of a Depository or anominee of a Depository.  This Securityis exchangeable for Securities registered in the name of a person other thanthe Depository or its nominee only in the limited circumstances described inthe Indenture and may not be transferred except as a whole by the Depository toa nominee of the Depository or by a nominee of the Depository to the Depositoryor another nominee of the Depository.

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