<TABLE> <S> <C>

<ARTICLE> 6
<CIK> 0000862502
<NAME> Salomon Brothers Large Cap Growth Fund
<SERIES>
   <NUMBER>012
   <NAME>Salomon Brothers Investment Series Funds Inc.

<S>                             <C>
<PERIOD-TYPE>                  6-MOS
<FISCAL-YEAR-END>                               Dec-31-2000
<PERIOD-END>                                    Jun-30-2000
<INVESTMENTS-AT-COST>                            12,513,523
<INVESTMENTS-AT-VALUE>                           13,643,175
<RECEIVABLES>                                       200,501
<ASSETS-OTHER>                                      471,199
<OTHER-ITEMS-ASSETS>                                      0
<TOTAL-ASSETS>                                   14,314,875
<PAYABLE-FOR-SECURITIES>                                  0
<SENIOR-LONG-TERM-DEBT>                                   0
<OTHER-ITEMS-LIABILITIES>                            66,416
<TOTAL-LIABILITIES>                                  66,416
<SENIOR-EQUITY>                                           0
<PAID-IN-CAPITAL-COMMON>                         13,909,861
<SHARES-COMMON-STOCK>                               173,199
<SHARES-COMMON-PRIOR>                               171,394
<ACCUMULATED-NII-CURRENT>                           (67,025)
<OVERDISTRIBUTION-NII>                                    0
<ACCUMULATED-NET-GAINS>                            (724,029)
<OVERDISTRIBUTION-GAINS>                                  0
<ACCUM-APPREC-OR-DEPREC>                          1,129,652
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<DIVIDEND-INCOME>                                    46,380
<INTEREST-INCOME>                                    13,313
<OTHER-INCOME>                                            0
<EXPENSES-NET>                                      126,718
<NET-INVESTMENT-INCOME>                             (67,025)
<REALIZED-GAINS-CURRENT>                           (715,775)
<APPREC-INCREASE-CURRENT>                           330,957
<NET-CHANGE-FROM-OPS>                              (451,843)
<EQUALIZATION>                                            0
<DISTRIBUTIONS-OF-INCOME>                                 0
<DISTRIBUTIONS-OF-GAINS>                              4,226
<DISTRIBUTIONS-OTHER>                                     0
<NUMBER-OF-SHARES-SOLD>                               1,799
<NUMBER-OF-SHARES-REDEEMED>                               0
<SHARES-REINVESTED>                                       6
<NET-CHANGE-IN-ASSETS>                            2,784,035
<ACCUMULATED-NII-PRIOR>                                   0
<ACCUMULATED-GAINS-PRIOR>                            25,000
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<INTEREST-EXPENSE>                                        0
<GROSS-EXPENSE>                                     165,979
<AVERAGE-NET-ASSETS>                              1,836,293
<PER-SHARE-NAV-BEGIN>                                11.180
<PER-SHARE-NII>                                      (0.020)
<PER-SHARE-GAIN-APPREC>                              (0.350)
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<RETURNS-OF-CAPITAL>                                  0.000
<PER-SHARE-NAV-END>                                  10.770
<EXPENSE-RATIO>                                        1.20



</TABLE>