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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549





FORM 10-Q







|x | Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
|- | ---------------------------------------------------------------------------------------

For the quarterly period ended June 30, 2010.

or



| ̈ | Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
|- | ----------------------------------------------------------------------------------------

For the Transition Period From  to
.

Commission file number
000-27436





Titan Pharmaceuticals, Inc.

(Exact name of registrant as specified in its charter)







|                                                               |  |                                     
|-------------------------------------------------------------- |  | ------------------------------------
|Delaware                                                       |  | 94-3171940                          
|(State or Other Jurisdiction of
Incorporation or Organization) |  | (I.R.S. Employer
Identification No.)

400 Oyster Point Blvd., Suite 505, South San Francisco, California 94080

(Address of Principal Executive Offices, Including Zip Code)

(650) 244-4990

(Registrants Telephone Number, Including Area Code)





Indicate by check mark whether the Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the
Exchange Act during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90
days.    Yes  x    No   ̈

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every
Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such
files).*    Yes   ̈    No   ̈ *The registrant has not yet been phased into the interactive data
requirements.

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a
non-accelerated filer. See the definitions of large accelerated filer, accelerated filer and smaller reporting company in Rule 12b-2 of the Exchange Act.



|                        |  |                                                 |  |                           |  |  
|----------------------- |  | ----------------------------------------------- |  | ------------------------- |  | -
|Large accelerated filer |  |  ̈                                               |  | Accelerated filer         |  |  ̈
|                        |  |                                                 | 
|Non-accelerated filer   |  |  ̈ (Do not check if a smaller reporting company) |  | Smaller reporting company |  | x

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange
Act).    Yes   ̈    No  x

There were 59,247,742 shares of the Registrants Common Stock issued and outstanding on August 11, 2010.









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Titan Pharmaceuticals, Inc.

Index to Form 10-Q



|                              |  |                                                                                                           |  |   
|----------------------------- |  | --------------------------------------------------------------------------------------------------------- |  | --
|Part I. Financial Information |  |                                                                                                          
|                              |  |                                                                                                          
|Item 1.                       |  | Financial Statements and notes (unaudited)                                                                |  | 3 
|                              |  |                                                                                                          
|                              |  | Condensed Consolidated Balance Sheets as of June 30, 2010 and December 31, 2009                           |  | 3 
|                              |  |                                                                                                          
|                              |  | Condensed Consolidated Statements of Operations for the three and six months ended June 30, 2010 and 2009 |  | 4 
|                              |  |                                                                                                          
|                              |  | Condensed Consolidated Statements of Cash Flows for the six months ended June 30, 2010 and 2009           |  | 5 
|                              |  |                                                                                                          
|                              |  | Notes to Condensed Consolidated Financial Statements                                                      |  | 6 
|                              |  |                                                                                                          
|Item 2.                       |  | Managements Discussion and Analysis of Financial Condition and Results of Operations                     |  | 11
|                              |  |                                                                                                          
|Item 3.                       |  | Quantitative and Qualitative Disclosures About Market Risk                                                |  | 14
|                              |  |                                                                                                          
|Item 4T.                      |  | Controls and Procedures                                                                                   |  | 14
|                              | 
|Part II. Other Information    |  |                                                                                                          
|                              |  |                                                                                                          
|Item 1A.                      |  | Risk Factors                                                                                              |  | 15
|                              |  |                                                                                                          
|Item 6.                       |  | Exhibits                                                                                                  |  | 16
|                              | 
|SIGNATURES                    |  | 17                                                                                                       



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Part I. Financial Information



|Item 1. | Financial Statements
|------- | --------------------

TITAN PHARMACEUTICALS, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS

(in thousands)



|                                                          |  |              |          |   |                  |   |          |  
|--------------------------------------------------------- |  | ------------ | -------- | - | ---------------- | - | -------- | -
|                                                          |  | June 30,2010 |          |   | December 31,2009 |  
|                                                          |  | (unaudited)  |          |   | (Note 1)         |  
|Assets                                                    |  |              |          |   |                  |   |          |  
|Current assets:                                           |  |              |          |   |                  |   |          |  
|Cash and cash equivalents                                 |  | $            | 1,452    |   |                  | $ | 3,300    |  
|Accounts receivable                                       |  |              | 381      |   |                  |   | 66       |  
|Prepaid expenses and other current assets                 |  |              | 179      |   |                  |   | 250      |  
|                                                          |  |              |          |   |                  |   |          |  
|Total current assets                                      |  |              | 2,012    |   |                  |   | 3,616    |  
|Property and equipment, net                               |  |              | 74       |   |                  |   | 110      |  
|                                                          |  |              |          |   |                  |   |          |  
|Total assets                                              |  | $            | 2,086    |   |                  | $ | 3,726    |  
|                                                          |  |              |          |   |                  |   |          |  
|Liabilities and Stockholders Deficit                     |  |              |          |   |                  |   |          |  
|Current liabilities                                       |  |              |          |   |                  |   |          |  
|Accounts payable                                          |  | $            | 625      |   |                  | $ | 335      |  
|Accrued clinical trials expenses                          |  |              | 380      |   |                  |   | 123      |  
|Other accrued liabilities                                 |  |              | 302      |   |                  |   | 564      |  
|Current portion of long-term debt                         |  |              | 1,085    |   |                  |   | 525      |  
|                                                          |  |              |          |   |                  |   |          |  
|Total current liabilities                                 |  |              | 2,392    |   |                  |   | 1,547    |  
|                                                          |  |              |          |   |                  |   |          |  
|Long-term debt, net of discount                           |  |              | 1,841    |   |                  |   | 2,386    |  
|                                                          |  |              |          |   |                  |   |          |  
|Total liabilities                                         |  |              | 4,233    |   |                  |   | 3,933    |  
|                                                          |  |              |          |   |                  |   |          |  
|Commitments and contingencies                             |  |              |          |   |                  |   |          |  
|Stockholders deficit                                     |  |              |          |   |                  |   |          |  
|Common stock, at amounts paid-in                          |  |              | 256,436  |   |                  |   | 256,436  |  
|Additional paid-in capital                                |  |              | 15,238   |   |                  |   | 15,027   |  
|Accumulated deficit                                       |  |              | (275,062 | ) |                  |   | (272,911 | )
|                                                          |  |              |          |   |                  |   |          |  
|Total Titan Pharmaceuticals, Inc.s stockholders deficit |  |              | (3,388   | ) |                  |   | (1,448   | )
|Non-controlling interest                                  |  |              | 1,241    |   |                  |   | 1,241    |  
|                                                          |  |              |          |   |                  |   |          |  
|Total stockholders deficit                               |  |              | (2,147   | ) |                  |   | (207     | )
|                                                          |  |              |          |   |                  |   |          |  
|Total liabilities and stockholders deficit               |  | $            | 2,086    |   |                  | $ | 3,726    |  
|                                                          |  |              |          |   |                  |   |          |  

See Notes to Condensed Consolidated Financial Statements



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TITAN PHARMACEUTICALS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(unaudited)

(in thousands, except per share amount)



|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|------------------------------------------------------------------------------ |  | -------------------------- | ------ | - | ------------------------ | - | ------ | ---- |  | - | ------ | - |  | - | ------ | -
|                                                                               |  | Three Months EndedJune 30, |        |   | Six Months EndedJune 30, |  
|                                                                               |  | 2010                       |        |   | 2009                     |   |        | 2010 |  |   | 2009   |  
|Revenue                                                                        |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Grant revenue                                                                  |  | $                          | 1,287  |   |                          | $ |       |      |  | $ | 2,048  |   |  | $ |       |  
|Royalty revenue                                                                |  |                            | 55     |   |                          |   |       |      |  |   | 1,708  |   |  |   |       |  
|License revenue                                                                |  |                            |       |   |                          |   | 29     |      |  |   | 11     |   |  |   | 52     |  
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Total revenue                                                                  |  |                            | 1,342  |   |                          |   | 29     |      |  |   | 3,767  |   |  |   | 52     |  
|Operating expenses:                                                            |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Research and development                                                       |  |                            | 2,056  |   |                          |   | 376    |      |  |   | 3,726  |   |  |   | 1,032  |  
|General and administrative                                                     |  |                            | 1,012  |   |                          |   | 1,393  |      |  |   | 1,947  |   |  |   | 1,847  |  
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Total operating expenses                                                       |  |                            | 3,068  |   |                          |   | 1,769  |      |  |   | 5,673  |   |  |   | 2,879  |  
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Loss from operations                                                           |  |                            | (1,726 | ) |                          |   | (1,740 | )    |  |   | (1,906 | ) |  |   | (2,827 | )
|Other income:                                                                  |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Interest income (expense), net                                                 |  |                            | (120   | ) |                          |   |       |      |  |   | (240   | ) |  |   | 2      |  
|Other income (expense)                                                         |  |                            |       |   |                          |   | 5      |      |  |   | (5     | ) |  |   |       |  
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Other income (expense), net                                                    |  |                            | (120   | ) |                          |   | 5      |      |  |   | (245   | ) |  |   | 2      |  
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Net loss                                                                       |  | $                          | (1,846 | ) |                          | $ | (1,735 | )    |  | $ | (2,151 | ) |  | $ | (2,825 | )
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Basic and diluted net loss per share                                           |  | $                          | (0.03  | ) |                          | $ | (0.03  | )    |  | $ | (0.04  | ) |  | $ | (0.05  | )
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  
|Weighted average shares used in computing basic and diluted net loss per share |  |                            | 59,248 |   |                          |   | 58,288 |      |  |   | 59,248 |   |  |   | 58,288 |  
|                                                                               |  |                            |        |   |                          |   |        |      |  |   |        |   |  |   |        |  

See Notes to Condensed Consolidated Financial Statements



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TITAN PHARMACEUTICALS, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(in thousands)

(unaudited)



|                                                                            |  |                         |        |   |      |   |        |  
|--------------------------------------------------------------------------- |  | ----------------------- | ------ | - | ---- | - | ------ | -
|                                                                            |  | Six Months EndedJune 30 |       
|                                                                            |  | 2010                    |        |   | 2009 |  
|Cash flows from operating activities:                                       |  |                         |        |   |      |   |        |  
|Net loss                                                                    |  | $                       | (2,151 | ) |      | $ | (2,825 | )
|Adjustments to reconcile net loss to net cash used in operating activities: |  |                         |        |   |      |   |        |  
|Depreciation and amortization                                               |  |                         | 49     |   |      |   | 98     |  
|Amortization of loan discount                                               |  |                         | 15     |   |      |   |       |  
|Loss on disposal of assets                                                  |  |                         |       |   |      |   | 3      |  
|Gain on sale of investments                                                 |  |                         |       |   |      |   | (9     | )
|Stock-based compensation                                                    |  |                         | 211    |   |      |   | 947    |  
|Changes in operating assets and liabilities:                                |  |                         |        |   |      |   |        |  
|Accounts receivable                                                         |  |                         | (315   | ) |      |   | 104    |  
|Prepaid expenses and other assets                                           |  |                         | 71     |   |      |   | 406    |  
|Accounts payable and other accrued liabilities                              |  |                         | 285    |   |      |   | (1,952 | )
|                                                                            |  |                         |        |   |      |   |        |  
|Net cash used in operating activities                                       |  |                         | (1,835 | ) |      |   | (3,228 | )
|                                                                            |  |                         |        |   |      |   |        |  
|Cash flows from investing activities:                                       |  |                         |        |   |      |   |        |  
|Purchases of furniture and equipment                                        |  |                         | (13    | ) |      |   | (10    | )
|Disposals of furniture and equipment                                        |  |                         |       |   |      |   | 2      |  
|Proceeds from maturities of marketable securities                           |  |                         |       |   |      |   | 9      |  
|                                                                            |  |                         |        |   |      |   |        |  
|Net cash provided by (used in) investing activities                         |  |                         | (13    | ) |      |   | 1      |  
|                                                                            |  |                         |        |   |      |   |        |  
|Cash flows from financing activities:                                       |  |                         |        |   |      |   |        |  
|Issuance of common stock, net                                               |  |                         |       |   |      |   |       |  
|                                                                            |  |                         |        |   |      |   |        |  
|Net cash provided by (used in) financing activities                         |  |                         |       |   |      |   |       |  
|                                                                            |  |                         |        |   |      |   |        |  
|Net decrease in cash and cash equivalents                                   |  |                         | (1,848 | ) |      |   | (3,227 | )
|Cash and cash equivalents at beginning of period                            |  |                         | 3,300  |   |      |   | 4,672  |  
|                                                                            |  |                         |        |   |      |   |        |  
|Cash and cash equivalents at end of period                                  |  | $                       | 1,452  |   |      | $ | 1,445  |  
|                                                                            |  |                         |        |   |      |   |        |  

See Notes to Condensed Consolidated Financial Statements



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TITAN PHARMACEUTICALS, INC.

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

(unaudited)

1.
Organization and Summary of Significant Accounting Policies

We are a biopharmaceutical company developing proprietary
therapeutics primarily for the treatment of central nervous system (CNS) disorders. We currently have two key assets:

(1) Fanapt (iloperidone), an atypical antipsychotic compound approved in the U.S. for the treatment of schizophrenia and being
marketed in the U.S. by Novartis Pharma AG. We are entitled to a royalty of 8-10% on U.S. net sales of Fanapt.

(2)
Probuphine®, a slow release implant formulation of buprenorphine that is capable of maintaining a stable, round
the clock blood level of the medicine in patients for six months following a single treatment. Probuphine is in Phase 3 clinical development for the treatment of opioid addiction, and we are currently enrolling patients in a confirmatory Phase 3
clinical study, which is expected to be completed in early second quarter 2011 with study results available by late second quarter 2011.

The ProNeura drug delivery technology underlying Probuphine has the potential to be used in developing products for the treatment of
other chronic conditions where maintaining stable, round the clock blood levels of a drug can benefit the patient and improve medical outcomes (e.g. chronic pain, Parkinsons disease).

We are directly developing our product candidates and also utilize resources provided through partnerships with other companies and
government organizations. These collaborations have helped to fund product development and have enabled us to retain significant economic interest in our products. We operate in only one business segment, the development of pharmaceutical products.

Basis of Presentation

The accompanying unaudited condensed consolidated financial statements include the accounts of Titan Pharmaceuticals, Inc. and its
subsidiaries after elimination of all significant intercompany accounts and transactions. Certain prior period balances have been reclassified to conform to the current period presentation. These financial statements have been prepared in accordance
with U.S. generally accepted accounting principles for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by
U.S. generally accepted accounting principles for a complete financial statement presentation. In the opinion of management, all adjustments (consisting of normal recurring adjustments) considered necessary for a fair presentation have been
included. Operating results for the three month period ended June 30, 2010 are not necessarily indicative of the results that may be expected for the year ending December 31, 2010, or any future interim periods.

The Balance Sheet at December 31, 2009 has been derived from the audited financial statements at that date, but does not include all
of the information and footnotes required by United States generally accepted accounting principles for complete financial statements.

The preparation of financial statements in conformity with U.S. generally accepted accounting principles requires management to make
estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. Actual results could differ from those estimates.

These unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial
statements and footnotes thereto for the year ended December 31, 2009 included in the Titan Pharmaceuticals, Inc. Registration Statement on Form 10/A, as filed with the Securities and Exchange Commission (SEC).

We have evaluated events that have occurred after June 30, 2010 and through the date that the unaudited financial statements were
issued.

We expect to continue to incur substantial additional operating losses from costs related to continuation of product
and technology development, clinical trials, and administrative activities. We believe that our working capital at June 30, 2010, together with proceeds available during the third quarter of 2010 from the two grants which were awarded by the
National Institutes of Health (NIH), will be sufficient, in light of faster than expected patient enrollment in the Probuphine development program, to sustain our planned operations into November, 2010. Accordingly, we are currently
seeking potential sources of capital in support of the Probuphine development program, which will supplement ongoing royalty revenues from sales of Fanapt. There can be no assurance that the funds we require will be available on favorable terms.

We may need to seek additional financing sources to fund our product development activities, and will be required to obtain
substantial funding to commercialize any products other than Fanapt that we may successfully develop. If we are unable to complete a debt or equity offering, or otherwise obtain sufficient financing when and if needed, we may be required to reduce,
defer or discontinue one or more of our product development programs.



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TITAN PHARMACEUTICALS, INC.

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(unaudited)



Majority-Owned Subsidiary

At June 30, 2010, we owned 81% of Ingenex (assuming the conversion of all preferred stock to common stock). Ingenex is not an
operating company and has no assets.

Revenue Recognition

We generate revenue principally from collaborative research and development arrangements, technology licenses, and government grants.
Revenue arrangements with multiple components are divided into separate units of accounting if certain criteria are met, including whether the delivered component has stand-alone value to the customer, and whether there is objective and reliable
evidence of the fair value of the undelivered items. Consideration received is allocated among the separate units of accounting based on their respective fair values, and the applicable revenue recognition criteria are then applied to each of the
units.

Revenue is recognized when the four basic criteria of revenue recognition are met: (1) a contractual agreement
exists; (2) transfer of technology has been completed or services have been rendered; (3) the fee is fixed or determinable; and (4) collectibility is reasonably assured. For each source of revenue, we comply with the above revenue
recognition criteria in the following manner:



| |  |  | Collaborative arrangements typically consist of non-refundable and/or exclusive technology access fees, cost reimbursements for specific research and
development spending, and various milestone and future product royalty payments. If the delivered technology does not have stand-alone value or if we do not have objective or reliable evidence of the fair value of the undelivered component, the
amount of revenue allocable to the delivered technology is deferred. Non-refundable upfront fees with stand-alone value that are not dependent on future performance under these agreements are recognized as revenue when received, and are deferred if
we have continuing performance obligations and have no evidence of fair value of those obligations. Cost reimbursements for research and development spending are recognized when the related costs are incurred and when collections are reasonably
expected. Payments received related to substantive, performance-based at-risk milestones are recognized as revenue upon achievement of the clinical success or regulatory event specified in the underlying contracts, which represent the
culmination of the earnings process. Amounts received in advance are recorded as deferred revenue until the technology is transferred, costs are incurred, or a milestone is reached.
| | - |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Technology license agreements typically consist of non-refundable upfront license fees, annual minimum access fees or royalty payments. Non-refundable
upfront license fees and annual minimum payments received with separable stand-alone values are recognized when the technology is transferred or accessed, provided that the technology transferred or accessed is not dependent on the outcome of our
continuing research and development efforts.
| | - |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Government grants, which support our research efforts in specific projects, generally provide for reimbursement of approved costs as defined in the
notices of grants. Grant revenue is recognized when associated project costs are incurred.
| | - |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Royalties earned are based on third-party sales of licensed products and are recorded in accordance with contract terms when third-party results are
reliably measurable and collectibility is reasonably assured. Pursuant to certain license agreements, we earn royalties on the sale of Fanapt by Novartis Pharma AG in the U.S. and Canada, and by Vanda Pharmaceuticals, Inc. in the rest of
the world. As described in Note 5, Commitments and Contingencies, we are obligated to pay royalties on such sales to Sanofi-Aventis. As we have no performance obligations under the license agreements, we have recorded the royalties earned,
net of royalties we are obligated to pay, as revenue in our consolidated statement of operations commencing with the six month period ended June 30, 2010.
| | - |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Research and Development Costs and Related Accrual

Research and development expenses include internal and external costs. Internal costs include salaries and employment related expenses,
facility costs, administrative expenses and allocations of corporate costs. External expenses consist primarily of costs associated with outsourced clinical research organization activities, sponsored research studies, process development and
product manufacturing expenses, product registration, patent application and prosecution, and investigator sponsored trials. We also record accruals for estimated ongoing clinical trial costs. Clinical trial costs represent costs incurred by
clinical research organizations, (CROs), and clinical sites. These costs are recorded as a component of research and development expenses. Under our agreements, progress payments are typically made to investigators, clinical sites and
CROs. We analyze the progress of the clinical trials, including levels of patient enrollment, invoices received and contracted costs when evaluating the adequacy of accrued liabilities. Significant judgments and estimates must be made and used in
determining the accrued balance in any accounting period. Actual results could differ from those estimates under different assumptions. Revisions are charged to expense in the period in which the facts that give rise to the revision become known.



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TITAN PHARMACEUTICALS, INC.

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(unaudited)



Recent Accounting Pronouncements

In April 2010, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update No. 2010-17 (ASU
2010-17), Revenue Recognition - Milestone Method, which provides a new guidance on the use of the milestone method of recognizing revenue for research and development arrangements under which consideration to be received by the vendor
is contingent upon the achievement of certain milestones. ASU 2010-17 is effective for fiscal years, and interim periods within such fiscal years, beginning on or after June 15, 2010, with early adoption permitted. We are currently evaluating
the potential impact, if any, of the adoption of this guidance on our financial position, results of operations and cash flows.

In February 2010, the FASB issued Accounting Standards Update No. 2010-09 (ASU 2010-09), Subsequent Events,
Amendments to Certain Recognition and Disclosure Requirements, which clarifies certain existing evaluation and disclosure requirements in ASC 855 related to subsequent events. ASU 2010-09 requires SEC filers to evaluate subsequent events through
the date on which the financial statements are issued and is effective immediately. The new guidance did not have an effect on our consolidated results of operations and financial condition.

In January 2010, the FASB issued Accounting Standards Update No. 2010-06 (ASU 2010-06), which amends the use of fair
value measures and the related disclosures. ASU 2010-06 requires new disclosures for transfers in and out of Level 1 and Level 2 fair value measurements. ASU 2010-06 is effective for the quarter ended June 30, 2010. The adoption of this new
standard did not have an impact on our consolidated financial statements.

In October 2009, the FASB issued Accounting
Standards Update No. 2009-13 (ASU 2009-13), Multiple-Deliverable Revenue Arrangements, which eliminates the residual method of allocation, and instead requires companies to use the relative selling price method when
allocating revenue in a multiple deliverable arrangement. ASU 2009-13 shall be effective in fiscal years beginning on or after June 15, 2010, with earlier application permitted. While we do not expect the adoption of this standard to have a
material impact on our financial position or results of operations, this standard may have an impact in the event we enter into future collaborative or multiple-deliverable transactions or modify existing collaborative relationships.

2. Stock Option Plans

The following table summarizes the share-based compensation expense recorded for awards under the stock option plans for the three and six
month periods ended June 30, 2010 and 2009:



|                                                 |  |                            |       |   |                          |   |       |      |  |   |       |   |  |   |       |  
|------------------------------------------------ |  | -------------------------- | ----- | - | ------------------------ | - | ----- | ---- |  | - | ----- | - |  | - | ----- | -
|.                                                |  | Three Months EndedJune 30, |       |   | Six Months EndedJune 30, |  
|(in thousands, except per share amounts)         |  | 2010                       |       |   | 2009                     |   |       | 2010 |  |   | 2009  |  
|Research and development                         |  | $                          | (45   | ) |                          | $ | 99    |      |  | $ | (30   | ) |  | $ | 38    |  
|General and administrative                       |  |                            | 119   |   |                          |   | 966   |      |  |   | 241   |   |  |   | 909   |  
|                                                 |  |                            |       |   |                          |   |       |      |  |   |       |   |  |   |       |  
|Total share-based compensation expenses          |  | $                          | 74    |   |                          | $ | 1,065 |      |  | $ | 211   |   |  | $ | 947   |  
|                                                 |  |                            |       |   |                          |   |       |      |  |   |       |   |  |   |       |  
|Increase in basic and diluted net loss per share |  | $                          | (0.01 | ) |                          | $ | (0.02 | )    |  | $ | (0.01 | ) |  | $ | (0.02 | )
|                                                 |  |                            |       |   |                          |   |       |      |  |   |       |   |  |   |       |  

No tax benefit was recognized related to share-based compensation expense since we have incurred operating
losses and we have established a full valuation allowance to offset all the potential tax benefits associated with our deferred tax assets.

We use the Black-Scholes-Merton option-pricing model with the following assumptions to estimate the share-based compensation expense for
the three and six month periods ended June 30, 2010 and 2009:



|                                                                  |  |                            |   |  |                          |   |  |      |   |  |      |  
|----------------------------------------------------------------- |  | -------------------------- | - |  | ------------------------ | - |  | ---- | - |  | ---- | -
|                                                                  |  | Three Months EndedJune 30, |   |  | Six months EndedJune 30, |  
|                                                                  |  | 2010                       |   |  | 2009                     |   |  | 2010 |   |  | 2009 |  
|Weighted-average risk-free interest rate                          |  | 1.4                        | % |  | 0.4                      | % |  | 2.3  | % |  | 0.4  | %
|Expected dividend payments                                        |  |                           |   |  |                         |   |  |     |   |  |     |  
|Expected holding period
(years)1                                  |  | 4.1                        |   |  | 4.6                      |   |  | 4.2  |   |  | 4.6  |  
|Weighted-average volatility
factor2                               |  | 1.94                       |   |  | 1.84                     |   |  | 1.89 |   |  | 1.84 |  
|Estimated forfeiture rates for options granted to
management3     |  | 23                         | % |  | 21                       | % |  | 23   | % |  | 21   | %
|Estimated forfeiture rates for options granted to
non-management3 |  | 41                         | % |  | 41                       | % |  | 41   | % |  | 41   | %



|(1) | Expected holding periods are based on historical data.
|--- | ------------------------------------------------------

|(2) | Weighted average volatility is based on the historical volatility of the Companys common stock.
|--- | ------------------------------------------------------------------------------------------------

|(3) | Estimated forfeiture rates are based on historical data.
|--- | --------------------------------------------------------



8



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##### Table of Contents

TITAN PHARMACEUTICALS, INC.

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(unaudited)



No options to purchase common stock were granted during the three month period ended
June 30, 2010. Based upon the above methodology, the weighted-average fair value of options valued during the three month period ended June 30, 2009 was $0.75.

The following table summarizes option activity for the six month period ended June 30, 2010:



|                                         |  |         |   |  |                              |      |                                    |      |                         |   |      
|---------------------------------------- |  | ------- | - |  | ---------------------------- | ---- | ---------------------------------- | ---- | ----------------------- | - | -----
|(in thousands, except per share amounts) |  | Options |   |  | WeightedAverageExercisePrice |      | WeightedAverageRemainingOptionTerm |      | AggregateIntrinsicValue
|Outstanding at January 1, 2010           |  | 6,070   |   |  | $                            | 3.68 |                                    | 6.42 |                         | $ | 4,794
|Granted                                  |  | 150     |   |  |                              | 2.36 |                                    |      |                         |   |      
|Exercised                                |  |        |   |  |                              |     |                                    |      |                         |   |      
|Expired or forfeited                     |  | (1,111  | ) |  |                              | 5.78 |                                    |      |                         |   |      
|                                         |  |         |   |  |                              |      |                                    |      |                         |   |      
|Outstanding at June 30, 2010             |  | 5,109   |   |  | $                            | 3.18 |                                    | 6.41 |                         | $ | 505  
|                                         |  |         |   |  |                              |      |                                    |      |                         |   |      
|Exercisable at June 30, 2010             |  | 3,515   |   |  | $                            | 4.16 |                                    | 5.27 |                         | $ | 270  
|                                         |  |         |   |  |                              |      |                                    |      |                         |   |      

As of June 30, 2010 there was approximately $0.9
million of total unrecognized compensation expense related to non-vested stock options. This expense is expected to be recognized over a weighted-average period of 2.9 years.

No shares of restricted stock were awarded during the three months ended June 30, 2010. The following table summarizes restricted
stock activity for the six month period ended June 30, 2010:



|                                         |  |        |  |                           |      |                                         |     |                         |   |   
|---------------------------------------- |  | ------ |  | ------------------------- | ---- | --------------------------------------- | --- | ----------------------- | - | --
|(in thousands, except per share amounts) |  | Shares |  | WeightedAverageFair Value |      | WeightedAverageRemainingContractualTerm |     | AggregateIntrinsicValue
|Outstanding at January 1, 2010           |  | 20     |  | $                         | 0.04 |                                         | 9.3 |                         | $ | 45
|Awarded                                  |  | 36     |  |                           |     |                                         |     |                         |   |   
|Exercised                                |  |       |  |                           |     |                                         |     |                         |   |   
|Cancelled                                |  |       |  |                           |     |                                         |     |                         |   |   
|                                         |  |        |  |                           |      |                                         |     |                         |   |   
|Outstanding at June 30, 2010             |  | 56     |  | $                         | 0.01 |                                         | 9.4 |                         | $ | 56
|                                         |  |        |  |                           |      |                                         |     |                         |   |   
|Vested at June 30, 2010                  |  | 54     |  | $                         | 0.01 |                                         | 9.4 |                         | $ | 54
|                                         |  |        |  |                           |      |                                         |     |                         |   |   

As of June 30, 2010 there was approximately
$1,000 of total unrecognized compensation expense related to non-vested awards. This expense is expected to be recognized over a weighted-average period of 1.3 years.

3. Net Loss Per Share

We calculate basic net loss per share using the weighted average common shares outstanding for the periods presented. Diluted net income
per share would include the impact of other dilutive equity instruments, primarily our options and warrants. For the periods ended June 30, 2010 and 2009, options and warrants totaled 11.9 million and 14.6 million shares,
respectively. We reported net losses for the periods presented and, therefore, options and warrants were excluded from the calculation of diluted net loss per share as they were anti-dilutive.

4. Comprehensive Loss

Comprehensive loss is comprised of net loss and other comprehensive income or loss. The only component of other comprehensive income or
loss is unrealized gains and losses on our marketable securities. Comprehensive losses for the three and six month periods ended June 30, 2010 were $1.8 million and $2.2 million, respectively, and for the three and six month periods ended
June 30, 2009 were $1.7 million and $2.8 million, respectively.

5. Commitments and Contingencies

Legal Proceedings

In March 2005, Dr. Bernard Sabel initiated an appraisal proceeding in the Court of Chancery of the State of Delaware relating to the
merger of our subsidiary ProNeura, Inc. into Titan. The complaint indicated that Mr. Sabel wanted the court to appraise the value of the 108,800 shares of the common stock of ProNeura owned by him. The complaint did not specify an amount that
Mr. Sabel considered the fair value of the shares. In March 2009, we settled our dispute with Dr. Sabel related to the merger of our subsidiary ProNeura, Inc. into Titan. In April 2009, under the terms of the settlement, we paid $600,000
to Dr. Sabel.



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##### Table of Contents

TITAN PHARMACEUTICALS, INC.

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS(Continued)

(unaudited)



Financing Agreements

In December 2009, we entered into a loan and security agreement with Oxford Capital Financing (Oxford) pursuant to which we
received a three-year term loan in the principal amount of $3,000,000 that bears interest at the rate of 13% per annum. We paid Oxford an initial facility fee of $60,000 and are obligated to make a final payment fee of $180,000. Commencing in
January 2010, the loan is repayable in monthly interest payments of $32,500 through June 2010 followed by monthly interest and principal installments of $117,625 commencing in July 2010 through December 2012. The loan is secured by our assets and
has a provision for pre-payment. We also issued to Oxford, in connection with the loan and security agreement, five-year warrants to purchase 42,254 shares of our common stock at an exercise price of $2.13 per share. The relative fair value
attributable to the warrants of $88,995 was recorded as a discount to the debt and corresponding credit to additional paid-in capital. The debt discount is being amortized to interest expense over the life of the debt.

Royalty Payments

In 1997, we entered into an exclusive license agreement with Sanofi-Aventis SA (formerly Hoechst Marion Roussel, Inc.). The agreement gave
us a worldwide license to the patent rights and know-how related to the antipsychotic agent Fanapt (iloperidone), including the ability to develop, use, sublicense, manufacture and sell products and processes claimed in the patent rights. Upon
commercialization of the product, the license agreement provides that we will pay royalties based on net sales. Net sales of Fanapt by Novartis during the three month period ended June 30, 2010 were approximately $693,000 and we are obligated
to pay royalties of approximately $104,000 to Sanofi-Aventis which was included in Accounts Receivable and Accounts Payable on the June 30, 2010 Balance Sheet.

6. Stockholders Equity

In December 2009, we completed the sale of 300,000 shares of our common stock to an institutional investor for gross proceeds of
approximately $510,000. Net proceeds were approximately $478,000.

In September and October 2009, members of our board of
directors exercised options to purchase 659,862 shares of our common stock at prices ranging from $0.79 to $1.40 per share. Net proceeds were approximately $555,000.



10



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##### Table of Contents

|Item 2. | Managements Discussion and Analysis of Financial Condition and Results of Operations
|------- | -------------------------------------------------------------------------------------

The following discussion contains certain forward-looking statements, within the meaning of the safe harbor provisions of
the Private Securities Reform Act of 1995, the attainment of which involves various risks and uncertainties. Forward-looking statements may be identified by the use of forward-looking terminology such as may, will,
expect, believe, estimate, plan, anticipate, continue, or similar terms, variations of those terms or the negative of those terms. Our actual results may differ materially from
those described in these forward-looking statements due to, among other factors, the results of research and development efforts, the results of pre-clinical and clinical testing, the effect of regulation by the United States Food and Drug
Administration (FDA) and other agencies, the impact of competitive products, product development, commercialization and technological difficulties, our ability to obtain additional financing, the effect of our accounting policies, and other risks
detailed in our SEC filings.

Probuphine
® and ProNeura are trademarks of Titan Pharmaceuticals, Inc. This Form 10-Q also includes trade
names and trademarks of companies other than Titan Pharmaceuticals, Inc.

References herein to we,
us, Titan, and our company refer to Titan Pharmaceuticals, Inc. and its subsidiaries unless the context otherwise requires.

Overview

We are a biopharmaceutical company developing proprietary therapeutics primarily for the treatment of central nervous system
(CNS) disorders. We currently have two key assets as described below:



| |  |  | Fanapt(iloperidone): An atypical antipsychotic approved by the U.S. Food and Drug Administration (FDA) for the treatment of
schizophrenia. Novartis Pharma AG (Novartis) has acquired the U.S. and Canadian rights to further develop and commercialize the approved oral formulation, which it launched in the U.S. in January 2010, and also further develop and
potentially commercialize an injectable form of the drug, known as a depot formulation. We are entitled to a royalty of 8-10% on U.S. net sales of all formulations through November 2016 (inclusive of a patent extension under the Patent Restoration
Act), with a possible six month extension for development of pediatric indications. Vanda Pharmaceuticals, Inc. (Vanda) has the development and commercialization rights to the oral and depot formulations of this product for the rest of
the world. Because patent coverage in most significant markets outside the U.S. has expired or will expire shortly, our royalties on any future sales in such markets will generally be limited.
| | - |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| |  |  | Probuphine: A slow release implant formulation of buprenorphine in Phase 3 clinical development for the treatment of opioid addiction that is
capable of maintaining a round the clock stable blood level of the drug in patients for six months following a single treatment. We have previously announced positive safety and efficacy results of this product in Phase 3 studies including a placebo
controlled Phase 3 study. In October 2009 we were awarded a $7.6 million grant from the National Institutes of Health (NIH) that will partially fund the second Phase 3 controlled safety and efficacy study required by the FDA for product
registration. We have recently provided an update on the confirmatory Phase 3 study currently enrolling patients at 20 U.S. sites, with full enrollment expected by the beginning of the fourth quarter of 2010, almost three months ahead of schedule,
and study results by late second quarter 2011.
| | - |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

The ProNeura long-term drug delivery technology underlying
Probuphine has the potential to be used in developing products for the treatment of other chronic conditions where maintaining stable, round the clock blood levels of a drug can benefit the patient and improve medical outcomes. We were recently
awarded a $0.5 million grant by the NIH under the Small Business Innovation Research (SBIR) program to conduct non-clinical studies in a model of Parkinsons disease using previously approved dopamine agonists and the ProNeura drug delivery
technology. We have also licensed certain rights from the University of Iowa to potentially use gallium maltolate for the treatment of chronic bacterial infections.

Our Products

The following table provides a summary status of our products:



|                      |  |                                     |  |                                                 |  |                                                     
|--------------------- |  | ----------------------------------- |  | ----------------------------------------------- |  | ----------------------------------------------------
|Product               |  | Approved or Potential Indication(s) |  | Phase of Development                            |  | Marketing Rights                                    
|Fanapt (iloperidone) |  | Schizophrenia                       |  | Approved in U.S. for treatment of schizophrenia |  | Novartis  U.S. and Canada
Vanda - Rest of the world
|                      |  |                                     | 
|Probuphine            |  | Opioid addiction                    |  | Phase 3                                         |  | Titan                                               

Fanapt was approved by the FDA in May
2009 for the treatment of schizophrenia and Novartis has acquired the rights to commercialize it in the U.S. and Canada. Novartis announced that it commenced commercial launch of Fanapt in mid January 2010 and has reported net sales of approximately
$21.4 million through June 30, 2010.



11



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Probuphine is currently in Phase 3 clinical development and has demonstrated safety and
efficacy in three Phase 3 studies, including one controlled Phase 3 study. However, additional clinical and manufacturing development is necessary prior to registration and it may still not be successfully developed or commercialized. Titan has been
awarded a $7.6 million grant by the NIH in partial support of the second controlled Phase 3 study, the total external cost of which is estimated at approximately $14.6 million. We will also require significant further capital, currently estimated at
approximately $3.9 million, to support third party expenses related to manufacturing development and testing, and possibly an addition $6.0 million for a long term safety study (one year treatment) prior to commercialization without giving effect to
the cost of additional clinical studies, if any, that may be required by the FDA. We may experience unanticipated problems relating to product development and cannot predict whether we will successfully develop and commercialize any products.

Titan was recently awarded an SBIR grant supporting the development of a long-term, non-fluctuating dopamine agonist
treatment for Parkinsons disease. The first year award in the amount of $300,000 will be available to Titan starting August 1, 2010, and an additional $195,000 for the second year starting August 1, 2011 has been recommended subject
to availability of funds and satisfactory progress of the project. The grant will be administered by the National Institute of Neurological Disorders and Stroke (NINDS).

Results of Operations for the Three and Six Months Ended June 30, 2010 and June 30, 2009

Our net loss for the three month period ended June 30, 2010 was approximately $1.8 million, or approximately $0.03 per share,
compared to our net loss of approximately $1.7 million, or approximately $0.03 per share, for the comparable period in 2009. Our net loss for the six month period ended June 30, 2010 was approximately $2.2 million, or approximately $0.04 per
share, compared to our net loss of approximately $2.8 million, or approximately $0.05 per share, for the comparable period in 2009.

We generated royalty revenues during the three and six month periods ended June 30, 2010 of approximately $55,000 and $1.7 million,
respectively. We had no royalty revenue during the comparable periods in 2009. We generated grant revenues during the three and six month periods ended June 30, 2010 of approximately $1.3 million and $2.0 million, respectively. We had no grant
revenue during the comparable periods in 2009. We generated no revenues from licensing agreements during the three month period ended June 30, 2010 and approximately $11,000 during the six month period ended June 30, 2010, compared to
approximately $29,000 and $52,000 for the comparable periods in 2009. Royalty revenues during the three and six month periods ended June 30, 2010 consisted of royalties on sales of Fanapt. Grant revenues during the three and six month periods
ended June 30, 2010 consisted of proceeds from the NIH grant related to our Probuphine program.

Research and development
expenses for the three month period ended June 30, 2010 were approximately $2.1 million, compared to approximately $0.4 million for the comparable period in 2009, an increase of $1.7 million, or 425%. Research and development expenses for the
six month period ended June 30, 2010 were approximately $3.7 million, compared to approximately $1.0 million for the comparable period in 2009, an increase of $2.7 million, or 270%. The increase in research and development costs during the
three and six month periods ended June 30, 2010 was primarily associated with an increase in external research and development expenses associated with the initiation and ongoing expenses of the Phase 3 clinical trials related to our Probuphine
product. External research and development expenses include direct expenses such as clinical research organization charges, investigator and review board fees, patient expense reimbursements and contract manufacturing expenses. During the three and
six month periods ended June 30, 2010, external research and development expenses relating to our Probuphine product development program were approximately $1.6 million and $2.6 million, respectively. Other research and development expenses
include internal operating costs such as clinical research and development personnel-related expenses, clinical trials related travel expenses, and allocation of facility and corporate costs. As a result of the risks and uncertainties inherently
associated with pharmaceutical research and development activities described elsewhere in this report, we are unable to estimate the specific timing and future costs of our clinical development programs or the timing of material cash inflows, if
any, from our product candidates.

General and administrative expenses for the three month period ended June 30, 2010
were approximately $1.0 million, compared to approximately $1.4 million for the comparable period in 2009, a decrease of $0.4 million, or 29%. General and administrative expenses for the six month period ended June 30, 2010 were approximately
$1.9 million, compared to approximately $1.8 million for the comparable period in 2009, an increase of $0.1 million, or 6%. The decrease in general and administrative expenses during the three month period ended June 30, 2010 was primarily
related to decreases in non-cash stock compensation costs of approximately $0.8 million and facilities and other administrative costs of approximately $0.1 million. This was offset in part by increases in legal fees of approximately $0.3 million and
consulting and professional fees of approximately $0.2 million. The increase in general and administrative expenses during the six month period ended June 30, 2010 was primarily related to increases in legal fees of approximately $0.3 million
and consulting and professional fees of approximately $0.7 million, employee related costs of $0.1 million and travel related costs of $0.1 million. This was offset in part by decreases in non-cash stock compensation costs of approximately $0.7
million, facilities and other administrative costs of approximately $0.4 million.

Net other expense for the three month
period ended June 30, 2010 was approximately $120,000, compared to net other income of approximately $5,000 in the comparable period in 2009. Net other expense for the six month period ended June 30, 2010 was



12



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##### Table of Contents

approximately $245,000, compared to net other income of approximately $2,000 in the comparable period in 2009. The increase in net other expense during the three and six month periods ended
June 30, 2010, was primarily related to interest expense of approximately $120,000 and $240,000, respectively, resulting from our loan with Oxford.

Liquidity and Capital Resources

We have funded our operations since inception primarily through sales of our securities, as well as with proceeds from warrant and option
exercises, corporate licensing and collaborative agreements, and government-sponsored research grants. At June 30, 2010, we had approximately $1.5 million of cash and cash equivalents compared to approximately $3.3 million at December 31,
2009.

Our operating activities used approximately $1.8 million during the six months ended June 30, 2010. This consisted
primarily of the net loss for the period of approximately $2.2 million and $0.3 million related to increases in accounts receivable, which includes approximately $0.1 million which will have to be paid to Sanofi-Aventis for royalties earned on sales
of Fanapt. This was offset in part by non-cash charges of approximately $0.2 million related to share-based compensation expenses and approximately $0.4 million related to net changes in other operating assets and liabilities. Uses of cash in
operating activities were primarily to fund product development programs and administrative expenses. Our license agreements with Sanofi-Aventis and MIT require us to pay royalties on future product sales. In addition, in order to maintain license
and other rights while products are under development, we must comply with customary licensee obligations, including the payment of patent-related costs, annual minimum license fees, meeting project-funding milestones and diligent efforts in product
development. The aggregate commitments we have under these agreements, including minimum license payments, for the next 12 months is approximately $100,000.

Net cash used by investing activities of approximately $13,000 during the six months ended June 30, 2010 consisted of purchases of
office equipment.

No cash was used in or provided by financing activities during the six month periods ended June 30,
2010 and 2009.

In December 2009, we entered into a financing agreement with Oxford Capital Financing pursuant to which we
received a three-year term loan in the principal amount of $3.0 million that bears interest at the rate of 13% per annum. Under this agreement, we will make payments totaling approximately $1.1 million during the next 12 months. We are
obligated to make a final payment fee of $180,000. The loan is secured by our assets and has a provision for pre-payment.

We
expect to continue to incur substantial additional operating losses from costs related to the continuation of product and technology development, clinical trials, and administrative activities. We believe that our working capital at June 30,
2010, together with proceeds from the NIH grants, in light of faster than expected patient enrollment in the Probuphine development program, will be sufficient to sustain our planned operations into November, 2010. Accordingly, we are currently
seeking potential sources of capital in support of the Probuphine development program, which will supplement ongoing royalty revenues from sales of Fanapt. There can be no assurance that the funds we require will be available on favorable terms.



13



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##### Table of Contents

|Item 3. | Quantitative and Qualitative Disclosures About Market Risk
|------- | ----------------------------------------------------------

This information has been omitted based on our status as a smaller reporting company.



|Item 4T. | Controls and Procedures
|-------- | -----------------------

Disclosure Controls and Procedures

Our President, being our principal executive and financial officer, has evaluated the effectiveness of our disclosure controls and
procedures as defined in Rules 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934 as of June 30, 2010, the end of the period covered by this report, and has concluded that our disclosure controls and procedures were effective to
ensure that the information required to be disclosed by us in reports we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the rules and forms of the SEC, and that such
information is accumulated and communicated to our principal executive and principal financial officer as appropriate to allow timely decisions regarding required disclosure.

Changes in Internal Control Over Financial Reporting

There were no changes in our internal control over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f) under the Securities
Exchange Act of 1934) during the three months ended June 30, 2010 that have materially affected, or are reasonably likely to materially affect, the Companys internal control over financial reporting.



14



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##### Table of Contents

PART II



|Item 1A. | Risk Factors
|-------- | ------------

This
information has been omitted based on our status as a smaller reporting company.



15



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##### Table of Contents

|Item 5. | Exhibits
|------- | --------



|       |  |                                                                                                                                                              
|------ |  | -------------------------------------------------------------------------------------------------------------------------------------------------------------
|No.    |  | Description                                                                                                                                                  
|       | 
|3.1    |  | Amended and Restated Certificate of Incorporation of the Registrant, as
amended9                                                                             
|       | 
|3.2    |  | By-laws of the
Registrant1                                                                                                                                   
|       | 
|4.1    |  | Registration Rights Agreement dated as of December 17,
20072                                                                                                 
|       | 
|4.2    |  | Registration Rights Agreement dated as of December 8,
20099                                                                                                  
|       | 
|4.3    |  | Warrant to Purchase Common Stock dated December 23, 2009 issued to Oxford Finance
Corporation9                                                               
|       | 
|10.1   |  | 1998 Stock Option
Plan3                                                                                                                                      
|       | 
|10.2   |  | 2001 Non-Qualified Employee Stock Option Plan4                                                                                                               
|       | 
|10.3   |  | 2002 Stock Option
Plan5                                                                                                                                      
|       | 
|10.4   |  | Employment Agreement between the Registrant and Sunil Bhonsle, dated May 16, 2009, as amended by agreement dated February 17,
20109                          
|       | 
|10.5   |  | Employment Agreement between the Registrant and Marc Rubin, dated May 16, 2009, as amended by agreement dated February 17,
20109                             
|       | 
|10.6   |  | Lease for the Registrants facilities, amended as of October 1,
20046                                                                                        
|       | 
|10.7   |  | Amendments to lease for Registrants facilities dated May 21, 2007 and March 12,
20099                                                                       
|       | 
|10.9*  |  | License Agreement between the Registrant and Sanofi-Aventis SA effective as of December 31,
19967                                                            
|       | 
|10.10* |  | Sublicense Agreement between the Registrant and Novartis Pharma AG dated November 20,
19978                                                                  
|       | 
|10.11* |  | License Agreement between the Registrant and the Massachusetts Institute of Technology dated September 28,
19951                                             
|       | 
|10.12  |  | Loan and Security Agreement between the Registrant and Oxford Finance Corporation dated December 18,
20099                                                   
|       | 
|10.13  |  | Stock Purchase Agreement between the Registrant and certain investors dated December 8,
20099                                                                
|       | 
|10.14  |  | Amendment to Employment Agreement dated June 15, 2010 between the Registrant and Marc
Rubin11                                                                
|       | 
|10.15  |  | Amendment to Employment Agreement dated June 15, 2010 between the Registrant and Sunil
Bhonsle11                                                             
|       | 
|10.16  |  | Amendment to lease for Registrants facilities dated June 15, 2010                                                                                           
|       | 
|14.1   |  | Code of Business Conduct and
Ethics10                                                                                                                        
|       | 
|31.1   |  | Certification of the Principal Executive and Financial Officer pursuant to Rule 13(a)-14(a) of the Securities Exchange of 1934                               
|       | 
|32.1   |  | Certificate of the Principal Executive and Financial Officer pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of
2002



|(1) | Incorporated by reference from the Registrants Registration Statement on Form SB-2 (File No. 33-99386).
|--- | --------------------------------------------------------------------------------------------------------

|(2) | Incorporated by reference from the Registrants Current Report on Form 8-K dated December 27, 2007.
|--- | ---------------------------------------------------------------------------------------------------

|(3) | Incorporated by reference from the Registrants definitive Proxy Statement filed on July 28, 2000.
|--- | --------------------------------------------------------------------------------------------------

|(4) | Incorporated by reference from the Registrants Annual Report on Form 10-K for the year ended December 31, 2001.
|--- | ----------------------------------------------------------------------------------------------------------------

|(5) | Incorporated by reference from the Registrants Annual Report on Form 10-K for the year ended December 31, 2002.
|--- | ----------------------------------------------------------------------------------------------------------------

|(6) | Incorporated by reference from the Registrants Annual Report on Form 10-K for the year ended December 31, 2005.
|--- | ----------------------------------------------------------------------------------------------------------------

|(7) | Incorporated by reference from the Registrants Annual Report on Form 10-KSB for the year ended December 31, 1996.
|--- | ------------------------------------------------------------------------------------------------------------------

|(8) | Incorporated by reference from the Registrants Registration Statement on Form S-3 (File No. 333-42367).
|--- | --------------------------------------------------------------------------------------------------------

|(9) | Incorporated by reference from the Registrants Registration Statement on Form 10 filed on January 14, 2010.
|--- | ------------------------------------------------------------------------------------------------------------

|(10) | Incorporated by reference from the Registrants Annual Report on Form 10-K for the year ended December 31, 2003.
|---- | ----------------------------------------------------------------------------------------------------------------

|(11) | Incorporated by reference from the Registrants Current Report on Form 8-K dated June 16, 2010.
|---- | -----------------------------------------------------------------------------------------------

|* | Confidential treatment has been granted with respect to portions of this exhibit.
|- | ---------------------------------------------------------------------------------



16



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##### Table of Contents

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its
behalf by the undersigned thereunto duly authorized.



|                       |  |                             |  |                                                                
|---------------------- |  | --------------------------- |  | ---------------------------------------------------------------
|                       |  | TITAN PHARMACEUTICALS, INC.
|                       |  |                            
|Dated: August 16, 2010 |  | By:                         |  | /S/    SUNIL
BHONSLE                                           
|                       |  | Name:                       |  | Sunil Bhonsle                                                  
|                       |  | Title:                      |  | President (Principal Executive and Principal Financial Officer)



17