Federal Register / Vol. 87, No. 80 / Tuesday, April 26, 2022 / Notices 24571 

3. Australian Patent 2010241864, 

issued June 5, 2014 (E–170–2009–0– 

AU–03); 

4. Canadian Patent 2,760,446, issued 

January 2, 2018 (E–170–2009–0–CA– 

04). 

5. European Patent 2424887, issued 

September 30, 2015 (E–170–2009–0– 

EP–05); and a. Validated in DE, FR and 

GB 

6. United States Patent 8,556,882, 

issued October 15, 2013 (E–170–2009– 

0–US–06). 

The patent rights in these inventions 

have been assigned and/or exclusively 

licensed to the government of the 

United States of America. 

The prospective exclusive license 

territory may be worldwide, and the 

field of use may be limited to the 

following: 

‘‘The use of the Licensed Patent 

Rights to develop, manufacture, 

distribute, sell, and use autologous 

tumor infiltrating lymphocyte (TIL) 

adoptive cell therapy products for the 

treatment of cancer. Specifically 

excluded from this Licensed Field of 

Use are adoptive cell therapy products 

genetically engineered to express a 

chimeric antigen receptor and/or T cell 

receptor.’’ 

E–170–2009 is primarily directed to 

recombinant constructs for the 

inducible expression of Interleukin-12 

(IL–12). IL–12 has been reported to be 

an important immunostimulatory 

cytokine; however, its clinical utility 

has been constrained, in part, by doselimiting toxicity following systemic 

administration. The subject invention 

potentially addresses this limitation by 

operatively associating a nuclear factor 

of activated T cells (NFAT) promoter 

with the coding sequence for IL–12. TIL 

engineered to express these constructs 

produce and secrete IL–12 at the site of 

antigen binding (exempli gratia, in the 

tumor microenvironment). 

This Notice is made in accordance 

with 35 U.S.C. 209 and 37 CFR part 404. 

The prospective exclusive license will 

be royalty bearing, and the prospective 

exclusive license may be granted unless 

within fifteen (15) days from the date of 

this published Notice, the National 

Cancer Institute receives written 

evidence and argument establishing that 

the grant of the license would not be 

consistent with the requirements of 35 

U.S.C. 209 and 37 CFR part 404. 

In response to this Notice, the public 

may file comments or objections. 

Comments and objections, other than 

those in the form of a license 

application, will not be treated 

confidentially and may be made 

publicly available. 

License applications submitted in 

response to this Notice will be 

presumed to contain business 

confidential information and any release 

of information from these license 

applications will be made only as 

required and upon a request under the 

Freedom of Information Act, 5 U.S.C. 

552. 

Dated: April 20, 2022. 

Richard U. Rodriguez, 

Associate Director, Technology Transfer 

Center, National Cancer Institute. 

[FR Doc. 2022–08795 Filed 4–25–22; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

U.S. Immigration and Customs 

Enforcement 

[OMB Control Number 1653–0026] 

Agency Information Collection 

Activities; Extension of a Currently 

Approved Collection: Information 

Relating to Beneficiary of Private Bill 

AGENCY: U.S. Immigration and Customs 

Enforcement, Department of Homeland 

Security. 

ACTION: 60-Day notice. 

SUMMARY: In accordance with the 

Paperwork Reduction Act (PRA) of 

1995, the Department of Homeland 

Security (DHS), U.S. Immigration and 

Customs Enforcement (ICE) will submit 

the following Information Collection 

Request (ICR) to the Office of 

Management and Budget (OMB) for 

review and clearance. 

DATES: Comments are encouraged and 

will be accepted until June 27, 2022. 

ADDRESSES: All submissions received 

must include the OMB Control Number 

1653–0026 in the body of the 

correspondence, the agency name and 

Docket ID ICEB–2006–0015. All 

comments received will be posted 

without change to http://

www.regulations.gov, including any 

personal information provided. Submit 

comments via the Federal eRulemaking 

Portal website at http://

www.regulations.gov under e-Docket ID 

number ICEB–2006–0015. 

FOR FURTHER INFORMATION CONTACT: If 

you have questions related to this 

revision, please contact: Ina Farka, ERO 

Policy Unit, (202) 732–3270, eropolicy@

ice.dhs.gov. (This is not a toll-free 

number. Comments are not accepted via 

telephone message). 

SUPPLEMENTARY INFORMATION: 

Comment 

Written comments and suggestions 

from the public and affected agencies 

concerning the proposed collection of 

information should address one or more 

of the following four points: 

(1) Evaluate whether the proposed 

collection of information is necessary 

for the proper performance of the 

functions of the agency, including 

whether the information will have 

practical utility; 

(2) Evaluate the accuracy of the 

agency’s estimate of the burden of the 

proposed collection of information, 

including the validity of the 

methodology and assumptions used; 

(3) Enhance the quality, utility, and 

clarity of the information to be 

collected; and 

(4) Minimize the burden of the 

collection of information on those who 

are to respond, including through the 

use of appropriate automated, 

electronic, mechanical, or other 

technological collection techniques or 

other forms of information technology, 

e.g., permitting electronic submission of 

responses. 

Overview of This Information 

Collection 

(1) Type of Information Collection: 

Extension of a Currently Approved 

Collection. 

(2) Title of the Form/Collection: 

Information Relating to Beneficiary of 

Private Bill. 

(3) Agency form number, if any, and 

the applicable component of the 

Department of Homeland Security 

sponsoring the collection: G–79A; U.S. 

Immigration and Customs Enforcement. 

(4) Affected public who will be asked 

or required to respond, as well as a brief 

abstract: Primary: State, Local, or Tribal 

Government. This form is used by ICE 

to obtain information from beneficiaries 

and/or interested parties in Private Bill 

cases when requested to report by the 

Committee on the Judiciary. 

(5) An estimate of the total number of 

respondents and the amount of time 

estimated for an average respondent to 

respond: 100 responses at 60 minutes (1 

hour) per response. 

(6) An estimate of the total public 

burden (in hours) associated with the 

collection: The total estimated annual 

hour burden is 100 hours. 

Dated: April 21, 2022. 

Scott Elmore, 

PRA Clearance Officer, U.S. Immigrations 

and Customs Enforcement, Department of 

Homeland Security. 

[FR Doc. 2022–08856 Filed 4–25–22; 8:45 am] 

BILLING CODE 9111–28–P 


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