<PAGE>   1

                                    FORM 10-Q

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

(Mark One)

[X]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE
       ACT OF 1934

For the quarterly period ended  March 31, 2001.
                                --------------
                                       OR

[ ]  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
       EXCHANGE ACT OF 1934

For the transition period from ________________ to ________________

Commission file number   000-23084.
                       ------------

                        INTEGRATED SILICON SOLUTION, INC.

                 Delaware                                  77-0199971.
        --------------------------------                   -------------------
        (State or other jurisdiction of                    (I.R.S Employer
        incorporation or organization)                     Identification No.)

         2231 Lawson Lane, Santa Clara, California               95054.
         ---------------------------------------------------------------------
        (Address of principal executive offices)               zip code

        Registrant's telephone number, including area code  (408) 588-0800.
                                                           -------------------

        Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.

Yes   x      No
    -----       -----

        The number of outstanding shares of the registrant's Common Stock as of
April 30, 2001 was 26,319,505
                   ----------

<PAGE>   2

                        INTEGRATED SILICON SOLUTION, INC.
                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (Unaudited)
                      (In thousands, except per share data)

<TABLE>
<CAPTION>
                                                     Three Months Ended         Six Months Ended
                                                          March 31,                  March 31,
                                                   ----------------------     ---------------------
                                                     2001          2000         2001         2000
                                                   --------      --------     --------     --------
<S>                                                <C>           <C>          <C>          <C>
Net sales (See Note 13)                            $ 52,023      $ 30,032     $117,252     $ 53,283
Cost of sales                                        48,564        21,232       91,618       38,203
                                                   --------      --------     --------     --------
Gross Profit                                          3,459         8,800       25,634       15,080
                                                   --------      --------     --------     --------

Operating Expenses:
  Research and development                            6,612         4,197       13,329        7,816
  Selling, general and administrative                 5,888         3,422       12,118        6,629
                                                   --------      --------     --------     --------
    Total operating expenses                         12,500         7,619       25,447       14,445
                                                   --------      --------     --------     --------

Operating income (loss)                              (9,041)        1,181          187          635
Other income (expense), net                           1,845           516        3,352          460
Gain on sale of ICSI                                  6,293            --        6,293           --
Gain on sale of other investments                     5,268            --       22,470           --
                                                   --------      --------     --------     --------
Income before income taxes and
  equity in net income of affiliated companies        4,365         1,697       32,302        1,095
Provision  for income taxes                           1,091           150        8,076          200
                                                   --------      --------     --------     --------

Net income before equity in
  net income of affiliated companies                  3,274         1,547       24,226          895

Equity in net income of
  affiliated companies                                1,195         1,838        5,318        2,984
                                                   --------      --------     --------     --------

Net income                                         $  4,469      $  3,385     $ 29,544     $  3,879
                                                   ========      ========     ========     ========

Basic income per share                             $   0.17      $   0.15     $   1.14     $   0.18
                                                   ========      ========     ========     ========
Shares used in basic per share calculation           26,093        21,992       25,957       21,185
                                                   ========      ========     ========     ========

Diluted income per share                           $   0.16      $   0.14     $   1.07     $   0.16
                                                   ========      ========     ========     ========
Shares used in diluted per share calculation         27,797        24,946       27,602       23,722
                                                   ========      ========     ========     ========
</TABLE>


     See accompanying notes to condensed consolidated financial statements.

<PAGE>   3

                        INTEGRATED SILICON SOLUTION, INC.
            CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME
                                   (Unaudited)
                                 (In thousands)

<TABLE>
<CAPTION>
                                                    Three Months Ended          Six Months Ended
                                                          March 31,                 March 31,
                                                   ---------------------     ----------------------
                                                     2001         2000         2001          2000
                                                   --------     --------     --------      --------
<S>                                                <C>          <C>          <C>           <C>
Net income                                         $  4,469     $  3,385     $ 29,544      $  3,879

Other comprehensive income (loss), net of tax:
   Change in cumulative translation adjustment          477          777         (534)        1,070
                                                   --------     --------     --------      --------

Comprehensive income                               $  4,946     $  4,162     $ 29,010      $  4,949
                                                   ========     ========     ========      ========
</TABLE>


     See accompanying notes to condensed consolidated financial statements.

<PAGE>   4

                        INTEGRATED SILICON SOLUTION, INC.
                      CONDENSED CONSOLIDATED BALANCE SHEETS
                                 (In thousands)

<TABLE>
<CAPTION>
                                                                      March 31,    September 30,
                                                                        2001           2000
                                                                      ---------    -------------
                                                                     (unaudited)        (1)
<S>                                                                   <C>            <C>
                                            ASSETS
Current assets:
  Cash and cash equivalents                                           $  27,318      $  38,778
  Short-term investments                                                113,200         58,800
  Accounts receivable                                                    34,655         26,525
  Accounts receivable from related parties (See Note 13)                    808          1,526
  Inventories                                                            74,948         63,217
  Other current assets                                                    3,817          1,271
                                                                      ---------      ---------

Total current assets                                                    254,746        190,117
Property, equipment, and leasehold improvements, net                      6,602          5,429
Other assets                                                             54,067         65,178
                                                                      ---------      ---------
Total assets                                                          $ 315,415      $ 260,724
                                                                      =========      =========

                             LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
  Accounts payable                                                    $  41,559      $  20,411
  Accounts payable to related parties (See Note 13)                       3,484         13,043
  Accrued compensation and benefits                                       3,600          2,424
  Accrued expenses                                                       10,845          7,513
  Income tax payable                                                      8,307            648
  Current portion of long-term obligations                                  148            140
                                                                      ---------      ---------

Total current liabilities                                                67,943         44,179
Income tax payable - non-current                                          4,996          4,996
Long-term obligations                                                       238            314

Stockholders' equity:
  Preferred stock                                                            --             --
  Common stock                                                                3              3
  Additional paid-in capital                                            219,829        217,845
  Retained earnings (accumulated deficit)                                26,718         (2,826)
  Accumulated comprehensive income                                       (4,303)        (3,769)
  Unearned compensation                                                      (9)           (18)
                                                                      ---------      ---------

Total stockholders' equity                                              242,238        211,235
                                                                      ---------      ---------
Total liabilities and stockholders' equity                            $ 315,415      $ 260,724
                                                                      =========      =========
</TABLE>


                 (1) Derived from audited financial statements.
     See accompanying notes to condensed consolidated financial statements.

<PAGE>   5

                        INTEGRATED SILICON SOLUTION, INC.
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                                   (Unaudited)
                                 (In thousands)

<TABLE>
<CAPTION>
                                                                                   Six Months Ended
                                                                                       March 31,
                                                                                ----------------------
                                                                                  2001          2000
                                                                                --------      --------
<S>                                                                             <C>           <C>
CASH FLOWS FROM OPERATING ACTIVITIES
  Net income                                                                    $ 29,544      $  3,879
  Gain on sale of investments                                                    (28,763)           --
  Depreciation and amortization                                                    1,597         1,531
  Equity in net income of affiliated companies                                    (5,318)       (2,984)
  Other charges to net loss not affecting cash                                        --           200
  Net effect of changes in current and other assets and current liabilities        4,209       (11,463)
                                                                                --------      --------
     Cash provided by (used in) operating activities                               1,269        (8,837)

CASH FLOWS FROM INVESTING ACTIVITIES
  Capital expenditures                                                            (2,770)       (2,698)
  Purchases of available-for-sale securities                                     (71,500)      (46,650)
  Sales of available-for-sale securities                                          17,100        10,650
  Proceeds from partial sale of Integrated Circuit Solution, Inc. ("ICSI")        13,250            --
  Investment in Wafertech, LLC ("Wafertech")                                          --        (2,667)
  Proceeds from the sale of Wafertech                                             40,669            --
  Investment in NexFlash                                                              --        (1,361)
  Proceeds from partial sale of NexFlash                                           6,167            --
  Investment in Semiconductor Manufacturing International Corp. ("SMIC")         (14,250)           --
  Other investments                                                               (3,320)           --
                                                                                --------      --------
     Cash used in investing activities                                           (14,654)      (42,726)

CASH FLOWS FROM FINANCING ACTIVITIES
  Proceeds from issuance of common stock                                           1,993        94,845
  Principal payments on notes payable and long-term obligations                      (68)          (82)
                                                                                --------      --------
     Cash provided by financing activities                                         1,925        94,763
                                                                                --------      --------

  Net increase (decrease) in cash and cash equivalents                           (11,460)       43,200
  Cash and cash equivalents at beginning of period                                38,778        15,975
                                                                                --------      --------
  Cash and cash equivalents at end of period                                    $ 27,318      $ 59,175
                                                                                ========      ========
</TABLE>


     See accompanying notes to condensed consolidated financial statements.

<PAGE>   6

                        INTEGRATED SILICON SOLUTION, INC.
              NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
                                   (Unaudited)


1.      BASIS OF PRESENTATION

        The accompanying condensed financial statements include the accounts of
Integrated Silicon Solution, Inc. (the "Company") and its consolidated majority
owned subsidiaries, after elimination of all significant intercompany accounts
and transactions and have been prepared in accordance with generally accepted
accounting principles for interim financial information and with Rule 10-01 of
Regulation S-X. Accordingly, they do not include all of the information and
footnotes required by generally accepted accounting principles for complete
financial statements. In the opinion of management, all adjustments (consisting
of normal recurring accruals) considered necessary for fair presentation have
been included.

        Operating results for the six months ended March 31, 2001 are not
necessarily indicative of the results that may be expected for the year ending
September 30, 2001.

2.       CONCENTRATIONS

        Sales to Flextronics International accounted for approximately 18% and
14% of total net sales for the three months ended March 31, 2001 and March 31,
2000, respectively and approximately 16% and 13% of total net sales for the six
months ended March 31, 2001 and March 31, 2000, respectively. Substantially all
of the sales to Flextronics were for products to be delivered to Cisco Systems,
Inc. Sales to 3Com accounted for approximately 6% and 11% of total net sales for
the three months ended March 31, 2001 and March 31, 2000, respectively, and
approximately 8% and 11% of total net sales for the six months ended March 31,
2001 and March 31, 2000, respectively.

3.      CASH, CASH EQUIVALENTS AND SHORT-TERM INVESTMENTS

        Cash, cash equivalents and short-term investments consisted of the
following:

<TABLE>
<CAPTION>
                                                                     (In thousands)
                                                                March 31     September 30
                                                                  2001           2000
                                                                  ----           ----
<S>                                                             <C>             <C>
             Cash                                               $ 16,871        $10,624
             Money market instruments                             10,447         28,154
             Municipal bonds due in more than 3 years            113,200         58,800
                                                                --------        -------
                                                                $140,518        $97,578
                                                                ========        =======
</TABLE>


                                       5
<PAGE>   7

                        INTEGRATED SILICON SOLUTION, INC.
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


4.      INVENTORIES

        The following is a summary of inventories by major category:

<TABLE>
<CAPTION>
                                                          (In thousands)
                                                     March 31      September 30
                                                      2001             2000
                                                      ----             ----
<S>                                                  <C>              <C>
             Purchased components                    $ 6,071          $17,566
             Work-in-process                          12,432           11,737
             Finished goods                           56,445           33,914
                                                     -------          -------
                                                     $74,948          $63,217
                                                     =======          =======
</TABLE>

5.      OTHER ASSETS

        Other assets consisted of the following:

<TABLE>
<CAPTION>
                                                         (In thousands)
                                                     March 31     September 30
                                                      2001            2000
                                                      ----            ----
<S>                                                  <C>             <C>
             Investment in ICSI                      $29,607         $31,525
             Investment in WaferTech, LLC                 --          23,467
             Investment in SMIC                       18,850           4,600
             Other                                     5,610           5,586
                                                     -------         -------
                                                     $54,067         $65,178
                                                     =======         =======
</TABLE>

6.      INCOME TAXES

        The provision for income taxes for the six month period ended March 31,
2001 is principally comprised of taxes on U.S. earnings and to a lesser extent
taxes on foreign earnings. The provision for income taxes for the six month
period ended March 31, 2000 is comprised of taxes on foreign earnings and
foreign withholding taxes. The effective tax rate of 25% for the six months
ended March 31, 2001 differs from the federal statutory rate as a result of the
reversal of valuation allowances previously established. A portion of the
valuation allowance previously established is now being realized as a result of
the current taxable income. The 25% effective tax rate is based on current tax
law, the current estimate of earnings and the expected distribution of income
among various tax jurisdictions, and is subject to change.


                                       6
<PAGE>   8

                        INTEGRATED SILICON SOLUTION, INC.
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


7.      NET INCOME PER SHARE

        The following table sets forth the computation of basic and diluted
earnings per share (in thousands, except per share amounts):

<TABLE>
<CAPTION>
                                                  Three Months Ended       Six Months Ended
                                                       March 31,               March 31,
                                                  -------------------     -------------------
                                                   2001        2000        2001        2000
                                                  -------     -------     -------     -------
<S>                                               <C>         <C>         <C>         <C>
Numerator for basic and diluted net income
  per share:
Net income                                        $ 4,469     $ 3,385     $29,544     $ 3,879
                                                  =======     =======     =======     =======
Denominator for basic net income per share:
   Weighted average common shares outstanding      26,093      21,992      25,957      21,185
Dilutive stock options                              1,704       2,433       1,609       2,048
Dilutive warrants                                      --         521          36         489
                                                  -------     -------     -------     -------
Denominator for diluted net income  per share      27,797      24,946      27,602      23,722
                                                  =======     =======     =======     =======

Basic net income per share                        $  0.17     $  0.15     $  1.14     $  0.18
                                                  =======     =======     =======     =======
Diluted net income per share                      $  0.16     $  0.14     $  1.07     $  0.16
                                                  =======     =======     =======     =======
</TABLE>

        The above diluted calculation for the three months ended March 31, 2001
does not include approximately 904,000 shares attributable to options as of
March 31, 2001 as their impact would be anti-dilutive. The above diluted
calculation for the six months ended March 31, 2001 and 2000, does not include
approximately 912,000 and 13,000 shares attributable to options as of March 31,
2001 and 2000, respectively, as their impact would be anti-dilutive.

8.      USE OF ESTIMATES

        The preparation of financial statements in conformity with generally
accepted accounting principles requires management to make estimates and
assumptions that affect the amounts reported in the financial statements and
accompanying notes. Actual results could differ from those estimates.

9.      IMPACT OF RECENTLY ISSUED ACCOUNTING STANDARDS

      In December 1999, the Securities and Exchange Commission ("SEC") issued
Staff Accounting Bulletin No. 101 ("SAB 101"), "Revenue Recognition", which
provides guidance on the recognition, presentation and disclosure of revenue in
financial statements filed with the SEC. SAB 101 outlines the basic criteria
that must be met to recognize revenue and provides guidance for disclosures
related to revenue recognition policies. The Company will be required to adopt
the provisions of SAB 101 in the fourth quarter of fiscal 2001. The Company
believes that its revenue recognition policy is in compliance with the
provisions of SAB 101 and that the adoption of SAB 101 will have no material
effect on its financial position or results of operations.


                                       7
<PAGE>   9


                        INTEGRATED SILICON SOLUTION, INC.
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


10.     LITIGATION

     In April 1998, the U.S. Department of Commerce ("DOC") published an
antidumping duty order on imports of SRAMs from Taiwan, from where the Company
currently imports a majority of its SRAMs. As a consequence of this antidumping
duty order, the Company is required to post a cash deposit on imports of Taiwan
fabricated SRAM wafers or devices at the ad valorem rate of 7.56%.

     On April 28, 2000, Micron Technology Inc. ("Micron") requested an
administrative review of the Company's Taiwan fabricated SRAMs for the period
from April 1, 1999 through March 31, 2000. For entries during this period, the
cash deposits could be returned to the Company or, alternatively, the Company
could forfeit amounts deposited and owe duties and interest in addition to the
amounts deposited, depending on results of the DOC administrative review. The
final results of the review are expected in calendar year 2001 and will
establish a new deposit rate for subsequent entries, which may be higher or
lower than the current rate.

     The Company has retained legal counsel to defend our interests in the
antidumping proceedings. In addition, respondents (including ISSI) have
challenged certain aspects of the antidumping determination in federal court
proceedings. On August 29, 2000, pursuant to an appeal by ISSI and other
respondents, the U.S. Court of International Trade affirmed the International
Trade Commission ("ITC") decision to reverse the ITC's earlier ruling supporting
the imposition of antidumping duties and rule instead in favor of respondents.
This decision by the Court of International Trade has been appealed by Micron to
the Federal Circuit Court of Appeals. If such appeal is not successful, the
antidumping case will be terminated, the order will be revoked, and we will be
entitled to a full refund of cash deposits. Pending resolution of the appeal,
the DOC will continue to administer the antidumping order.

     Duties calculated and assessed by the government could have a material
adverse affect on the Company's gross margins and profits. Any reviews or
proceedings might not mitigate or eliminate antidumping duties.

11.     LONG TERM OBLIGATIONS

   The Company leases certain of its equipment under a capital lease. The lease
is collateralized by the underlying assets. At March 31, 2001, property and
equipment with a cost of $600,000 was subject to this financing arrangement.
Related accumulated amortization at March 31, 2001 amounted to $200,000. Under
the terms of the lease, the Company owes monthly payments of $15,108 through
September 1, 2003. Remaining principal and interest payments were $385,390 and
$52,843, respectively, at March 31, 2001.


                                       8
<PAGE>   10

                        INTEGRATED SILICON SOLUTION, INC.
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


12.     GEOGRAPHIC AND SEGMENT INFORMATION

   The Company has one operating segment, which is to design, develop, and
market high-performance SRAM, DRAM, and other memory products. The following
table summarizes the Company's operations in different geographic areas:

<TABLE>
<CAPTION>
                                                          Six months ended
                                                             March 31,
                                                        2001             2000
                                                      ---------        --------
                                                           (In thousands)
<S>                                                   <C>              <C>
Net Sales
   To customer from U.S. operations                   $ 106,275        $ 46,382
   To customer from Hong Kong operations                 10,977           6,901
   Intercompany from U.S.                                11,295           6,864
   Intercompany from Hong Kong                              187           1,004
                                                      ---------        --------
                                                        128,734          61,151
                                                      ---------        --------
   Eliminations                                         (11,482)         (7,868)
                                                      ---------        --------
   Total net sales                                    $ 117,252        $ 53,283
                                                      =========        ========

Operating income
   U.S. operations                                    $   1,129        $    200
   Hong Kong operations                                    (536)            901
   China operations                                        (253)             --
                                                      ---------        --------
                                                            340           1,101
                                                      ---------        --------
   Eliminations                                            (153)           (466)
                                                      ---------        --------
   Total operating income                             $     187        $    635
                                                      =========        ========

Long-lived assets
   U.S. operations                                    $   6,034        $  6,182
   Hong Kong operations                                     307             148
   China operations                                         261              --
                                                      ---------        --------
   Total long-lived assets                            $   6,602        $  6,330
                                                      =========        ========
</TABLE>

13.     RELATED PARTY TRANSACTIONS

   For the six months ended March 31, 2001 and March 31, 2000, the Company sold
approximately $185,000 and $718,000, respectively, of memory products to ICSI in
which the Company currently has approximately a 31% ownership. The Company also
provides services and licenses certain products to ICSI. At March 31, 2001 and
2000, the Company had an accounts receivable balance from ICSI of approximately
$291,000 and $636,000, respectively.

   The Company purchases goods and contract manufacturing services from ICSI.
For the six months ended March 31, 2001 and March 31, 2000, purchases of goods
and services were approximately $11,049,000 and $32,506,000, respectively. At
March 31, 2001 and 2000, the Company had an accounts payable balance to ICSI of
approximately $3,374,000 and $12,151,000, respectively.


                                       9
<PAGE>   11

                        INTEGRATED SILICON SOLUTION, INC.
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


   For the six months ended March 31, 2001 and March 31, 2000, the Company sold
approximately $0 and $212,000, respectively, of memory products to NexFlash
Technology, Inc. ("NexFlash"), in which the Company currently has approximately
a 14% ownership. In addition, the Company received approximately $83,000 in
sublease income from NexFlash in the both the three months ended March 31, 2001
and March 31, 2000. The Company also provides NexFlash various administrative
support services for which it is reimbursed. At March 31, 2001 and 2000, the
Company had an accounts receivable balance from NexFlash of approximately
$215,000 and $522,000, respectively.

   The Company purchases goods and services from NexFlash. For the six months
ended March 31, 2001 and March 31, 2001, purchases of goods and services were
approximately $0 and $127,000, respectively. At March 31, 2001 and 2000, the
Company had an accounts payable balance to NexFlash of approximately $0 and
$142,000, respectively.

   The Company provides goods and services to GetSilicon.Net, an equity
investee, in which the Company currently has approximately a 31% ownership. For
the six months ended March 31, 2001 and March 31, 2000, the Company provided
goods and services of approximately $302,000 and $0, respectively, to
GetSilicon.Net. At March 31, 2001, the Company had an accounts receivable
balance from GetSilicon.Net of approximately $302,000.

   In January 2001, the Company entered into an agreement for
business-to-business data exchange and application services with GetSilicon.Net.
For the six months ended March 31, 2001, the purchase of services under this
agreement was approximately $110,000. At March 31, 2001, the Company had an
accounts payable balance to GetSilicon.Net of approximately $110,000.

14.     INVESTMENT IN INTEGRATED CIRCUIT SOLUTION INCORPORATION ("ICSI")

   The following summarizes financial information for ICSI, an equity investee.
(In thousands)

<TABLE>
<CAPTION>
                                                                    March 31,          September 30,
                                                                      2001                 2000
                                                                      ----                 ----
<S>                                                                 <C>                  <C>
             Current assets                                         $102,848             $109,428
             Property, plant, and equipment and other assets          51,709               45,873
             Current liabilities                                      41,748               53,037
             Long-term debt                                           11,596               15,517
</TABLE>

<TABLE>
<CAPTION>
                                                                         Six Months Ended
                                                                            March 31,
                                                                       2001           2000
                                                                      -------        -------
<S>                                                                   <C>            <C>
        Net sales                                                     $82,059        $59,674
        Gross profit                                                   28,705         15,825
        Net income                                                     16,965          8,526
</TABLE>


                                       10
<PAGE>   12

                        INTEGRATED SILICON SOLUTION, INC.
        NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)


15.     TRANSACTIONS

        In December 2000, the Company sold its investment of $23.5 million in
WaferTech, LLC to Taiwan Semiconductor Manufacturing Corporation for $40.7
million resulting in a gain of $17.2 million.

        On January 16, 2001, ICSI completed an initial public offering in
Taiwan. As a result of shares of ICSI sold by the Company in the initial public
offering and subsequently, the Company recorded gross proceeds of approximately
$8.1 million in the March 2001 quarter resulting in a gain of $6.3 million.

        In February 2001, the Company, along with other shareholders, sold a
portion of their ownership in NexFlash to Winbond International Corporation for
$6.2 million resulting in a gain of $5.3 million. As a result of this
transaction, the Company's ownership percentage decreased from approximately 32%
to approximately 14%. Subsequent to the completion of the transaction, the
Company accounts for NexFlash on the cost basis.

        In February 2001, the Company invested $2.8 million for approximately
22% of E-CMOS Technology Corporation ("E-CMOS") located in Hsin-Chu, Taiwan,
R.O.C. The Company will account for E-CMOS on the equity basis and record its
percentage gain or loss on a one quarter lag.




                                       11
<PAGE>   13

ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS

        We have made forward-looking statements in this report on Form 10-Q that
are subject to risks and uncertainties. Forward-looking statements include
information concerning possible or assumed future results of our operations.
Also, when we use such words as "believe," "expect," "anticipate," or similar
expressions, we are making forward-looking statements. Our actual results could
differ materially from those anticipated in these forward-looking statements as
a result of certain factors, including those set forth below and elsewhere in
this report on Form 10-Q.

BACKGROUND

        Integrated Silicon Solution, Inc. was founded in October 1988. We
design, develop and market high performance memory semiconductors used in
Internet access devices, networking equipment, telecom and mobile communications
equipment, and computer peripherals. Our high speed and low power SRAMs and our
low to medium density DRAMs enable customers to design products that meet the
demanding connectivity and portability requirements of the data communications
and wireless communications markets. Our objective is to capitalize on major
trends such as the expansion of the communications and Internet infrastructure,
the proliferation of wireless devices, and other trends in electronics
technologies. Our goal is to be a focused supplier of high performance memories
targeting the growing connectivity and communications markets.

        We believe our close relationship with leading silicon wafer foundries
gives us access to the advanced wafer process technology required to design and
manufacture high performance memories. We entered into our first development
program with Taiwan Semiconductor Manufacturing Corporation ("TSMC") in 1990 and
our next development program with Chartered Semiconductor in 1994 and have also
worked closely with United Microelectronics Corporation ("UMC") since 1995.
Through this collaborative strategy, we have been at the forefront in utilizing
the most advanced process technology for memories and in securing access to
wafer capacity. We believe our ability to design and develop high performance,
cost-effective products, and our collaborative development with our
manufacturing partners utilizing state-of-the-art process technology, gives us a
competitive advantage.

RESULTS OF OPERATIONS

        Our financial results for fiscal 2001 and fiscal 2000 reflect accounting
for ICSI and GetSilicon.Net on the equity basis and include our percentage share
of the results of their respective operations. Our financial results for fiscal
2001 and for fiscal 2000 through the period ended January 31, 2001, reflect
accounting for Nexflash on the equity basis and include our percentage share of
the results of their operations. Effective February 2001, as our ownership of
NexFlash became less than 20%, we began accounting for NexFlash on the cost
basis. At March 31, 2001, we owned approximately 31% of ICSI, approximately 14%
of NexFlash and approximately 31% of GetSilicon.Net.


THREE MONTHS ENDED MARCH 31, 2001 COMPARED TO THREE MONTHS ENDED MARCH 31, 2000

        Net Sales. Net sales consist principally of total product sales less
estimated sales returns. Net sales increased by 73% to $52.0 million in the
three months ended March 31, 2001 from $30.0 million in the three months ended
March 31, 2000. The increase in sales was principally due to an increase in unit
shipments of our SRAM products, specifically our 32K x 32, 256K, 128K x 16 and
64K x 16 SRAM products, as well as increased unit shipments of 16 megabit and 2
megabit DRAM products. In addition, the average selling prices for certain of
our SRAM products generally increased in the three months ended March 31, 2001
compared to the three months ended March 31, 2000. We anticipate that the
average selling prices of our existing products will generally decline over
time, although the rate of decline may fluctuate for certain products. In this
regard, we experienced a decline in the average selling prices for certain of
our products in the three months ended March 31, 2001 as compared to the three
months ended December 31, 2000. We anticipate a further decline in the average
selling prices for certain of our products in the three months ended June 30,
2001. There can be


                                       12
<PAGE>   14

no assurance that such declines will be offset by higher volumes or by higher
prices on newer products. In this regard, we experienced a decrease in unit
shipments for certain of our products in the three months ended March 31, 2001
as compared to the three months ended December 31, 2000 and we anticipate a
further decline in the three months ended June 30, 2001.

        Sales to Flextronics International accounted for approximately 18% and
14% of total net sales for the three months ended March 31, 2001 and March 31,
2000, respectively. Substantially all of the sales to Flextronics were for
products to be delivered to Cisco Systems, Inc. Shipments for Cisco directly, or
indirectly through subcontractors, accounted for approximately 21% of total net
sales for the three months ended March 31, 2001. Sales to 3Com accounted for
approximately 6% and 11% of total net sales for the three months ended March 31,
2001 and March 31, 2000, respectively. Shipments for 3Com directly, or
indirectly through subcontractors, accounted for approximately 11% of total net
sales for the three months ended March 31, 2001. As sales to these customers are
executed pursuant to purchase orders and no purchasing contract exists, these
customers can cease doing business with us at any time.

        Gross Profit. Cost of sales includes die cost from the wafers acquired
from foundries, subcontracted package costs, assembly costs and test costs,
costs associated with in-house product testing, quality assurance and import
duties. Gross profit decreased 61% to $3.5 million in the three months ended
March 31, 2001 from $8.8 million in the three months ended March 31, 2000. As a
percentage of net sales, gross profit decreased to 6.6% in the three months
ended March 31, 2001 from 29.3% in the three months ended March 31, 2000. In the
three months ended March 31, 2001, we recorded an inventory write-down of $11.7
million predominately for lower of cost or market accounting on certain of our
products, primarily DRAMs and low power SRAMs. Excluding the inventory
write-downs in the three months ended March 31, 2001, gross profit for the
period was $15.2 million or 29.1% of net sales. Excluding the inventory
write-downs in the three months ended March 31, 2001, the increase in gross
profit was principally due to an increase in unit shipments of our SRAM
products, specifically our 32K x 32, 256K, 128K x 16 and 64K x 16 SRAM products,
as well as increased unit shipments of 16 megabit and 2 megabit DRAM products.
In addition, while the gross margin percentage for SRAMs increased in the three
months ended March 31, 2001 compared to the three months ended March 31, 2000,
the gross margin percentage for DRAMs declined resulting in a gross margin
percentage that declined slightly overall. We believe that the average selling
price of our products will generally decline over time and, unless we are able
to reduce our cost per unit to the extent necessary to offset such declines, the
decline in average selling prices will result in a material decline in our gross
margin. In this regard, we experienced a decline in the average selling prices
for certain of our products in the three months ended March 31, 2001 as compared
to the three months ended December 31, 2000. We anticipate a further decline in
the average selling prices for certain of our products in the three months ended
June 30, 2001. In addition, product unit costs could increase if suppliers raise
prices, which could result in a material decline in our gross margin. Although
we have product cost reduction programs in place for certain products that
involve efforts to reduce internal costs and supplier costs, there can be no
assurance that product costs will be reduced or that such reductions will be
sufficient to offset the expected declines in average selling prices. We do not
believe that such cost reduction efforts are likely to have a material adverse
impact on the quality of our products or the level of service we provide.

        Research and Development. Research and development expenses increased by
58% to $6.6 million in the three months ended March 31, 2001 from $4.2 million
in the three months ended March 31, 2000. As a percentage of net sales, research
and development expenses decreased to 12.7% in the three months ended March 31,
2001 from 14.0% in the three months ended March 31, 2000. The increase in
absolute dollars was primarily the result of an increase in engineering
personnel and payroll related expenses, and increased expenses related to the
development of new products. As a result of expense controls instituted in light
of current economic conditions, we anticipate that our research and development
expenses will remain constant or decrease slightly in absolute dollars in future
periods, although such expenses may fluctuate as a percentage of net sales.

        Selling, General and Administrative. Selling, general and administrative
expenses increased by 72% to $5.9 million in the three months ended March 31,
2001 from $3.4 million in the three months ended


                                       14
<PAGE>   15

March 31, 2000. As a percentage of net sales, selling, general and
administrative expenses decreased to 11.3% in the three months ended March 31,
2001 from 11.4% in the three months ended March 31, 2000. The increase in
absolute dollars was primarily the result of increased selling commissions
associated with higher revenues in the three months ended March 31, 2001
compared to the three months ended March 31, 2000. In addition, payroll related
expenses increased in the three months ended March 31, 2001 compared to the
three months ended March 31, 2000 as a result of the addition of marketing,
sales and administrative personnel to support our expanding business. As a
result of expense controls instituted in light of current economic conditions,
we expect our selling, general and administrative expenses will remain constant
or decrease slightly in absolute dollars in future periods although such
expenses may fluctuate as a percentage of net sales.

        Gain on sale of investments. On January 16, 2001, ICSI completed an
initial public offering in Taiwan. As a result of shares of ICSI sold by us in
the initial public offering and subsequently, we recorded gross proceeds of
approximately $8.1 million in the March 2001 quarter resulting in a gain of $6.3
million. In February 2001, we, along with other shareholders, sold a portion of
our ownership in NexFlash to Winbond International Corporation for $6.2 million
resulting in a gain of $5.3 million.

        Other income (expense), net. Other income (expense), net increased by
$1.3 million to approximately $1.8 million in the three months ended March 31,
2001 from $0.5 million in the three months ended March 31, 2000. The increase
resulted from increased interest income as a result of higher cash balances from
the sale of our investments in WaferTech, NexFlash and ICSI and our follow-on
public stock offering in February 2000.

        Provision for Income Taxes. The income tax provision for the three month
period ended March 31, 2000 is comprised of taxes on foreign earnings. The
provision for income taxes for the three month period ended March 31, 2001 is
principally comprised of taxes on U.S. earnings. The effective tax rate of 25%
for the three months ended March 31, 2001 differs from the federal statutory
rate as a result of the reversal of valuation allowances previously established.
A portion of the valuation allowance previously established is now being
realized as a result of the current taxable income. The 25% effective tax rate
is based on current tax law, the current estimate of earnings and the expected
distribution of income among various tax jurisdictions, and is subject to
change.

        Equity in net income of affiliated companies. Equity in net income of
affiliated companies decreased by $0.6 million to $1.2 million in the three
months ended March 31, 2001 from $1.8 million in the three months ended March
31, 2000. This primarily reflects a decrease in income from our percentage share
of ICSI's financial results in the three months ended March 31, 2001 compared to
the three months ended March 31, 2000.

SIX MONTHS ENDED MARCH 31, 2001 COMPARED TO SIX MONTHS ENDED MARCH 31, 2000

        Net Sales. Net sales increased by 120% to $117.3 million in the six
months ended March 31, 2001, from $53.3 million in the six months ended March
31, 2000. The increase in sales was principally due to an increase in unit
shipments of our SRAM products, specifically our 32K x 32, 1024K, 256K, 128K x
16 and 64K x 16 SRAM products, as well as increased unit shipments of 16 megabit
DRAM products. In addition, the average selling prices of our SRAM and DRAM
products generally increased in the six months ended March 31, 2001 compared to
the six months ended March 31, 2000. We anticipate that the average selling
prices of our existing products will generally decline over time, although the
rate of decline may fluctuate for certain products. In this regard, we
experienced a decline in the average selling prices for certain of our products
in the three months ended March 31, 2001 as compared to the three months ended
December 31, 2000. We anticipate a further decline in the average selling prices
for certain of our products in the three months ended June 30, 2001. There can
be no assurance that such declines will be offset by higher volumes or by higher
prices on newer products. In this regard, we experienced a decrease in unit
shipments for certain of our products in the three months ended March 31, 2001
as compared to the three months ended December 31, 2000 and we anticipate a
further decline in the three months ended June 30, 2001.


                                       14
<PAGE>   16

        Sales to Flextronics International accounted for approximately 16 and
13% of total net sales for the six months ended March 31, 2001 and March 31,
2000, respectively. Substantially all of the sales to Flextronics were for
products to be delivered to Cisco Systems, Inc. Shipments for Cisco directly, or
indirectly through subcontractors, accounted for approximately 18% of total net
sales for the six months ended March 31, 2001. Sales to one customer, 3Com,
accounted for approximately 8% and 11% of total net sales for the six months
ended March 31, 2001 and March 31, 2000, respectively. Shipments for 3Com
directly, or indirectly through subcontractors, accounted for approximately 12%
of total net sales for the six months ended March 31, 2001. As sales to these
customers are executed pursuant to purchase orders and no purchasing contract
exists, these customers can cease doing business with us at any time.

        Gross Profit. Gross profit increased 70% to $25.6 million in the six
months ended March 31, 2001, from $15.1 million in the six months ended March
31, 2000. As a percentage of net sales, gross profit decreased to 21.9% in the
six months ended March 31, 2001 from 28.3% in the six months ended March 31,
2000. In the three months ended March 31, 2001, we recorded an inventory
write-down of $11.7 million predominately for lower of cost or market accounting
on certain of our products, primarily DRAMs and low power SRAMs. Excluding the
inventory write-downs in the six months ended March 31, 2001, gross profit for
the period was $37.3 million or 31.8% of net sales. Excluding the inventory
write-downs in the six months ended March 31, 2001, the increase in gross profit
was principally due to an increase in unit shipments of our SRAM products,
specifically our 32K x 32, 1024K, 256K, 128K x 16 and 64K x 16 SRAM products, as
well as increased unit shipments of 16 megabit DRAM products. In addition,
increases in the average selling prices of our SRAM and DRAM products in the six
months ended March 31, 2001 compared to the six months ended March 31, 2001 more
than offset any increases in product costs while certain product costs declined
resulting in higher gross margins. Our gross profit also benefited from $0.2
million and $0.7 million of licensing revenue for the six months ended March 31,
2001 and March 31, 2000, respectively. We believe that the average selling price
of our products will generally decline over time and, unless we are able to
reduce our cost per unit to the extent necessary to offset such declines, the
decline in average selling prices will result in a material decline in our gross
margin. In this regard, we experienced a decline in the average selling prices
for certain of our products in the three months ended March 31, 2001 as compared
to the three months ended December 31, 2000. We anticipate a further decline in
the average selling prices for certain of our products in the three months ended
June 30, 2001. In addition, product unit costs could increase if suppliers raise
prices, which could result in a material decline in our gross margin. Although
we have product cost reduction programs in place for certain products that
involve efforts to reduce internal costs and supplier costs, there can be no
assurance that product costs will be reduced or that such reductions will be
sufficient to offset the expected declines in average selling prices. We do not
believe that such cost reduction efforts are likely to have a material adverse
impact on the quality of our products or the level of service provided by us.

        Research and Development. Research and development expenses increased by
71% to $13.3 million in the six months ended March 31, 2001, from $7.8 million
in the six months ended March 31, 2000. As a percentage of net sales, research
and development expenses decreased to 11.4% in the six months ended March 31,
2001, from 14.7% in the six months ended March 31, 2000. The increase in
absolute dollars was primarily the result of an increase in engineering
personnel and payroll related expenses, and increased expenses related to the
development of new products. As a result of expense controls instituted in light
of current economic conditions, we anticipate that our research and development
expenses will remain constant or decrease slightly in absolute dollars in future
periods, although such expenses may fluctuate as a percentage of net sales.

        Selling, General and Administrative. Selling, general and administrative
expenses increased by 83% to $12.1 million in the six months ended March 31,
2001 from $6.6 million in the six months ended March 31, 2000. As a percentage
of net sales, selling, general and administrative expenses decreased to 10.3% in
the six months ended March 31, 2001, from 12.4% in the six months ended March
31, 2000. The increase in absolute dollars was primarily the result of increased
selling commissions associated with higher revenues in the six months ended
March 31, 2001 compared to the six months ended March 31, 2000. In addition,
payroll related expenses increased in the six months ended March 31, 2001
compared to the six months ended March 31, 2000 as a result of the addition of
marketing, sales and administrative personnel to support our expanding


                                       15
<PAGE>   17

business. As a result of expense controls instituted in light of current
economic conditions, we expect our selling, general and administrative expenses
will remain constant or decrease slightly in absolute dollars in future periods
although such expenses may fluctuate as a percentage of net sales.

        Gain on sale of investments. In the three months ended December 31,
2000, we sold our interest in WaferTech to TSMC for approximately $40.7, which
resulted in a pre-tax gain of $17.2 million. On January 16, 2001, ICSI completed
an initial public offering in Taiwan. As a result of shares of ICSI sold by us
in the initial public offering and subsequently, we recorded gross proceeds of
approximately $8.1 million in the March 2001 quarter resulting in a gain of $6.3
million. In February 2001, we, along with other shareholders, sold a portion of
our ownership in NexFlash to Winbond International Corporation for $6.2 million
resulting in a gain of $5.3 million.

        Other income (expense), net. Other income (expense), net increased by
$2.9 million to $3.4 million in the six months ended March 31, 2001 from $0.5
million in the six months ended March 31, 2000. The increase resulted from
increased interest income as a result of higher cash balances from the sale of
our investments in Watertech, NexFlash and ICSI and our follow-on public stock
offering in February 2000.

        Equity in net income of affiliated companies. Equity in net income of
affiliated companies increased by $2.3 million to $5.3 million in the six months
ended March 31, 2001 from $3.0 million in the six months ended March 31, 2000.
This primarily reflects an increase in income from our percentage share of
ICSI's financial results in the six months ended March 31, 2001 compared to the
six months ended March 31, 2000.

      Provision (benefit) for Income Taxes. The provision for income taxes for
the six month period ended March 31, 2000 is comprised of taxes on foreign
earnings and foreign withholding taxes. The provision for income taxes for the
six month period ended March 31, 2001 is principally comprised of taxes on U.S.
earnings. The effective tax rate of 25% for the three months ended March 31,
2001 differs from the federal statutory rate as a result of the reversal of
valuation allowances previously established. A portion of the valuation
allowance previously established is now being realized as a result of the
current taxable income. The 25% effective tax rate is based on current tax law,
the current estimate of earnings and the expected distribution of income among
various tax jurisdictions, and is subject to change.

LIQUIDITY AND CAPITAL RESOURCES

     As of March 31, 2001, our principal sources of liquidity included cash,
cash equivalents and short-term investments of approximately $140.5 million.
During the six months ended March 31, 2001, operating activities provided cash
of approximately $1.3 million. Cash provided by operations was primarily due to
net income of $29.5 million adjusted for the gain on the sale of investments of
$28.8 million, equity in net income of affiliated companies of $5.3 million and
depreciation of $1.6 million. In addition, increases in accounts payable of
$11.6 million and income tax payable of $7.6 million were partially offset by
increases in inventories of $11.7 million and accounts receivable of $7.4
million.

     In the six months ended March 31, 2001, we used $14.7 million for investing
activities compared to $42.7 million in the six months ended March 31, 2000. The
cash used for investing activities during the six months ended March 31, 2001
was primarily the result of net purchases of available-for-sale securities of
$54.4 million. We made an additional investment of $14.3 million in
Semiconductor Manufacturing International Corp ("SMIC"), a foundry currently
under construction in Shanghai, China. We made other investments of $3.3
million, including $2.8 million for a 22% interest in E-CMOS a semiconductor
company located in Hsin-Chu, Taiwan. We generated $40.7 million from the sale of
our investment in WaferTech to TSMC. We also generated $13.3 million from the
sale of shares of ICSI stock and $6.2 million for the of NexFlash shares. The
cash used for investing activities for the six months ended March 31, 2000 was
primarily the result of net purchases of available-for-sale securities of $36.0
million.

     In the six months ended March 31, 2001, we made capital expenditures of
approximately $2.8 million for engineering tools and computer software. We
expect to spend approximately $10.0 million to purchase


                                       16
<PAGE>   18

capital equipment during the next twelve months, principally for the purchase of
design and engineering tools, additional test equipment and computer software
and hardware.

     We generated $1.9 million from financing activities during the six months
ended March 31, 2001 compared to $94.8 million in the six months ended March 31,
2000. Cash generated from financing activities for the six months ended March
31, 2001 was primarily the result of proceeds from the issuance of common stock
of $2.0 million from option exercises and sales under our employee stock
purchase plan. The cash generated in the six months ended March 31, 2000
included net proceeds from our follow-on public stock offering in the March 2000
quarter of $90.6 million.

     In June 1998, we sold approximately 46% of ICSI to a group of private
investors. In fiscal 1999 and fiscal 2000, we sold more of our holdings in ICSI
to private investors. In the three months ended December 31, 2000, we received
$5.1 million from the sale of shares of ICSI under the 1998 ISSI-Taiwan Stock
Plan. On January 16, 2001, ICSI completed an initial public offering in Taiwan.
As a result of shares of ICSI sold by the Company in the initial public offering
and subsequently, we recorded gross proceeds of approximately $8.1 million in
the March 2001 quarter resulting in a gain of $6.3 million. As of March 31, 2001
we owned approximately 31% of ICSI.

     In August 2000, we entered into a wafer fabrication facility investment
agreement with SMIC. Under the terms of this agreement, we have committed to
invest $30.0 million. We have received certain capacity commitments from SMIC.
In the six months ended March 31, 2001, we made an additional investment of
$14.3 million in SMIC. As of March 31, 2001, we had invested $18.9 million in
this foundry, and an additional $11.1 million is expected to be invested in
fiscal year 2002.

     In June 1996, we entered into a business venture called WaferTech, LLC with
TSMC, Altera, Analog Devices, and private investors to build a wafer fabrication
facility in Camas, Washington. In December 2000, we sold our investment of $23.5
million in WaferTech to TSMC for $40.7 million resulting in a pre-tax gain of
$17.2 million.

     In fiscal 1995, we agreed to certain minimum wafer purchase commitments
with TSMC in exchange for wafer capacity commitments through 2001. We also
agreed to make certain annual payments to TSMC, the remaining amount of which
totals approximately $4.8 million through 2001, for additional capacity above
the annual base capacity. Wafer purchases in any given year are first applied to
the base capacity and then to our $4.8 million obligation. As a result, the $4.8
million may be subject to forfeiture if we do not purchase the base capacity and
additional capacity for which we have contracted. We do not currently expect to
forfeit any amounts or incur any losses associated with these capacity
agreements. Although we have rights to re-schedule or assign capacity to another
party, there can be no assurance that such re-schedule or assignment would be
successfully accomplished. Should we fail to re-schedule or assign unneeded
capacity, our business and operating results could be adversely affected.

     In April 1998, the U.S. Department of Commerce ("DOC") published an
antidumping duty order on imports of SRAMs from Taiwan, from where we currently
import a majority of our SRAMs. As a consequence of this antidumping duty order,
we are required to post a cash deposit on imports of Taiwan fabricated SRAM
wafers or devices at the ad valorem rate of 7.56%.

     On April 28, 2000, Micron Technology Inc. ("Micron") requested an
administrative review of our Taiwan fabricated SRAMs for the period from April
1, 1999 through March 31, 2000. For entries during this period, the cash
deposits could be returned to us or, alternatively, we could forfeit amounts
deposited and owe duties and interest in addition to the amounts deposited,
depending on results of the DOC administrative review. The final results of the
review are expected in calendar year 2001 and will establish a new deposit rate
for subsequent entries, which may be higher or lower than the current rate.

     We have retained legal counsel to defend our interests in the antidumping
proceedings. In addition, respondents (including ISSI) have challenged certain
aspects of the antidumping determination in federal


                                       17
<PAGE>   19

court proceedings. On August 29, 2000, pursuant to an appeal by ISSI and other
respondents, the U.S. Court of International Trade affirmed the International
Trade Commission ("ITC") decision to reverse the ITC's earlier ruling supporting
the imposition of antidumping duties and rule instead in favor of respondents.
This decision by the Court of International Trade has been appealed by Micron to
the Federal Circuit Court of Appeals. If such appeal is not successful, the
antidumping case will be terminated, the order will be revoked, and we will be
entitled to a full refund of cash deposits. Pending resolution of the appeal,
the DOC will continue to administer the antidumping order.

     Duties calculated and assessed by the government could have a material
adverse affect on our gross margins and profits. Any reviews or proceedings
might not mitigate or eliminate antidumping duties.

     We believe our existing funds and available financing will satisfy our
anticipated working capital and other cash requirements through at least the
next 12 months. We may from time to time take actions to further increase our
cash position through bank borrowings, sales of additional shares of ICSI, the
disposition of certain assets, equity financing or debt financing. From time to
time, we may also evaluate potential acquisitions and equity investments
complementary to our memory expertise and market strategy, including investments
in wafer fabrication foundries. To the extent we pursue such transactions, any
such transaction could require us to seek additional equity or debt financing to
fund such activities. There can be no assurance that any such additional
financing could be obtained on terms acceptable to us, if at all.


CERTAIN FACTORS WHICH MAY AFFECT OUR BUSINESS OR FUTURE OPERATING RESULTS

OUR OPERATING RESULTS ARE EXPECTED TO CONTINUE TO FLUCTUATE AND MAY NOT MEET
PUBLISHED ANALYST FORECASTS. THIS MAY CAUSE THE PRICE OF OUR COMMON STOCK TO
DECLINE.

     Our future quarterly and annual operating results are subject to
fluctuations due to a wide variety of factors, including:

     -  the cyclicality of the semiconductor industry;

     -  declines in average selling prices of our products;

     -  cancellation of existing orders or the failure to secure new orders;

     -  oversupply of memory products in the market;

     -  our failure to introduce new products and to implement technologies on a
        timely basis;

     -  market acceptance of ours and our customers' products;

     -  the failure to anticipate changing customer product requirements;

     -  fluctuations in manufacturing yields;

     -  failure to deliver products to customers on a timely basis;

     -  disruption in the supply of wafers or assembly services;

     -  changes in product mix;

     -  the timing of significant orders;

     -  increased expenses associated with new product introductions or process
        changes;


                                       18
<PAGE>   20

     -  the ability of customers to make payments to us; and

     -  increases in antidumping duties.

WE HAVE A RECENT HISTORY OF LOSSES, AND THERE CAN BE NO ASSURANCE THAT WE WILL
BE ABLE TO SUSTAIN PROFITABILITY IN THE FUTURE.

     We incurred losses of $9.5 million and $50.6 million in fiscal 1999 and
1998, respectively. We were profitable for fiscal 2000 and the first six months
of fiscal 2001. Our ability to maintain profitability on a quarterly basis in
the future will depend on a variety of factors, including our ability to
increase our net sales, introduce new products on a timely basis, secure
sufficient wafer fabrication capacity and control our operating expenses.
Adverse developments with respect to these or other factors could result in
quarterly or annual operating losses in the future.

OUR SALES DEPEND ON SRAM PRODUCTS, AND A DECLINE IN AVERAGE SELLING PRICES OR
REDUCED DEMAND FOR THESE PRODUCTS COULD HARM OUR BUSINESS.

     A majority of our net sales are derived from the sale of SRAM products,
which are subject to unit volume fluctuations and declines in average selling
prices which could harm our business. For example, in the three months ended
March 31, 2001, our net sales decreased by 20% to $52.0 million from $65.2
million in the three months ended December 31, 2000, principally due to a
decrease in unit shipments of our SRAM products. We anticipate that sales will
decrease again in the three months ended June 30, 2001. Further, we anticipate
that the average selling prices of our existing products will decline over time,
although the rate of decline may fluctuate for certain products. Such declines
may not be offset by higher volumes or by higher prices on newer products.

WE MAY NOT BE ABLE TO COMPENSATE FOR PRICE DECREASES IN OUR PRODUCTS.

     Competitive pricing pressures due to an industry-wide oversupply of wafer
capacity resulted in significant price decreases for our products during fiscal
1996 through fiscal 1999. While we experienced increases in average selling
prices in fiscal 2000, historically, average selling prices for semiconductor
memory products have declined, and we expect that average selling prices will
decline in the future. In that regard, we experienced a decline in the average
selling prices for certain of our products in the three months ended March 31,
2001 as compared to the three months ended December 31, 2000. We anticipate a
further decline in the average selling prices for certain of our products in the
three months ended June 30, 2001. Our ability to maintain or increase revenues
will depend upon our ability to increase unit sales volume of existing products
and introduce and sell new products which compensate for the anticipated
declines in the average selling prices of our existing products.

     Declining average selling prices will also adversely affect our gross
margins and profits unless we are able to introduce new products with higher
margins or reduce our cost per unit. We may not be able to increase unit sales
volumes, introduce and sell new products or reduce our cost per unit.

SHIFTS IN INDUSTRY-WIDE CAPACITY MAY CAUSE OUR RESULTS TO FLUCTUATE. IN THE
PAST, SUCH SHIFTS HAVE RESULTED IN SIGNIFICANT INVENTORY WRITE-DOWNS.

     Shifts in industry-wide capacity from shortages to oversupply or from
oversupply to shortages may result in significant fluctuations in our quarterly
or annual operating results. The semiconductor industry is highly cyclical and
is subject to significant downturns resulting from excess capacity,
overproduction, reduced demand or technological obsolescence. These factors can
result in a decline in average selling prices and the stated value of inventory.
In the three months ended March 31, 2001, we recorded inventory write-downs of
$11.7 million. The inventory write-downs were predominately for lower of cost or
market accounting on certain of our products, primarily DRAMs and low power
SRAMs. In fiscal 1998, we recorded inventory


                                       19
<PAGE>   21

write-downs of $23.0 million. The inventory write-downs were predominately for
lower of cost or market accounting on certain of our products, primarily SRAMs,
and, to a lesser extent, excess inventory.

     We also write down to zero carrying value inventory on hand in excess of
six months' estimated sales volumes to cover estimated exposures, unless
adjustments are made to the forecast based on management's judgments for newer
products, end of life products or planned inventory increases. In making such
judgments to write down inventory, management takes into account the product
life cycles which can range from 6 to 24 months, the stage in the life cycle of
the product, the impact of competitors' announcements and product introductions
on our products, and purchasing opportunities due to excess wafer capacity.

     We believe that six months is an appropriate period because it is difficult
to accurately forecast for a specific product beyond this time frame due to the
potential introduction of products by competitors, technology obsolescence or
fluctuations in demand. Our policy regarding excess inventory resulted in
inventory write-downs for excess inventory of approximately $5.4 million for
fiscal year 1998. Future additional inventory write-downs may occur due to lower
of cost or market accounting, excess inventory or inventory obsolescence.

IF WE ARE UNABLE TO OBTAIN AN ADEQUATE SUPPLY OF WAFERS, OUR BUSINESS WILL BE
HARMED.

     If we are unable to obtain an adequate supply of wafers from our current or
any alternative sources in a timely manner, our business will be harmed. To
date, our principal manufacturing relationship has been with TSMC, from which we
have obtained a majority of our wafers. We also receive wafers from Chartered
Semiconductor and UMC. Each of our wafer foundries also supplies wafers to other
integrated circuit companies, including certain of our competitors. Although we
have written commitments specifying wafer capacities from our suppliers, if
these suppliers experience manufacturing failures or yield shortfalls, choose to
prioritize capacity for other uses, or reduce or eliminate deliveries to us, we
may not be able to enforce fulfillment of the delivery commitments.
Additionally, we may not be able to qualify additional manufacturing sources for
existing or new products in a timely manner and we cannot be certain that other
manufacturing sources would agree to deliver an adequate supply of wafers to us.

FOUNDRY CAPACITY CAN BE LIMITED AND WE MAY BE REQUIRED TO ENTER INTO COSTLY
LONG-TERM SUPPLY ARRANGEMENTS TO SECURE FOUNDRY CAPACITY.

     If we are not able to obtain additional foundry capacity as required, our
relationships with our customers would be harmed and our future sales would be
adversely impacted. In order to secure additional foundry capacity, we have
entered into and expect to enter into various arrangements with suppliers, which
could include:

     -  contracts that commit us to purchase specified quantities of silicon
        wafers over extended periods;

     -  investments in foundries;

     -  joint ventures;

     -  other partnership relationships with foundries;

     -  option payments or other prepayments to foundries; or

     -  nonrefundable deposits with or loans to foundries in exchange for
        capacity commitments.

     We may not be able to make any such arrangements in a timely fashion or at
all, and such arrangements, if any, may not be on terms favorable to us.
Moreover, if we are able to secure foundry capacity, we may be obligated to
utilize all of that capacity or incur penalties. Such penalties may be expensive
and could harm our financial results.


                                       20
<PAGE>   22

ANY DOWNTURN IN THE MARKETS WE SERVE WOULD HARM OUR BUSINESS.

     A majority of our products are incorporated into products such as internet
access devices, networking equipment, and telecom/mobile communications devices.
Historically, these markets have from time to time experienced cyclical,
depressed business conditions, often in connection with, or in anticipation of,
a decline in general economic conditions. Such industry downturns have resulted
in reduced product demand and declining average selling prices. These markets
are currently experiencing severely depressed business conditions which are
adversely affecting our business.

WE DEPEND ON A SMALL NUMBER OF CUSTOMERS FOR A HIGH PERCENTAGE OF OUR SALES, AND
THE LOSS OF A SIGNIFICANT CUSTOMER COULD CAUSE A DECLINE IN OUR PROFITS.

        Sales to Flextronics International accounted for approximately 16% of
total net sales for the six months ended March 31, 2001. Substantially all of
the sales to Flextronics were for products to be delivered to Cisco Systems,
Inc. Shipments for Cisco directly, or indirectly through subcontractors,
accounted for approximately 18% of total net sales for the six months ended
March 31, 2001. Sales to 3Com accounted for approximately 8% of total net sales
for the six months ended March 31, 2001. Shipments for 3Com directly, or
indirectly through subcontractors, accounted for approximately 12% of total net
sales for the six months ended March 31, 2001. In fiscal 2000, no single
customer accounted for over 10% of net sales. However, in fiscal 2000, shipments
for Cisco directly, or indirectly through subcontractors, accounted for
approximately 13% of net revenue. In fiscal 1999 and 1998, one customer, 3Com,
accounted for approximately 20% and 19% of net sales, respectively. As sales to
these customers are executed pursuant to purchase orders and no purchasing
contract exists, these customers can cease doing business with us at any time.
In this regard, we experienced order cancellations from these customers in the
March 2001 quarter. We expect a significant portion of our future sales to
remain concentrated within a limited number of strategic customers. We may not
be able to retain our strategic customers, such customers may cancel or
reschedule orders, or in the event of canceled orders, such orders may not be
replaced by other sales. In addition, sales to any particular customer may
fluctuate significantly from quarter to quarter, and such fluctuating sales
could harm our business.

OUR PRODUCTS ARE COMPLEX AND COULD CONTAIN DEFECTS, WHICH COULD REDUCE SALES OF
THOSE PRODUCTS OR RESULT IN CLAIMS AGAINST US.

     We develop complex and evolving products. Despite testing by us and our
customers, errors may be found in existing or new products. This could result in
a delay in recognition or loss of revenues, loss of market share or failure to
achieve market acceptance. These defects also may cause us to incur significant
warranty, support and repair costs, may divert the attention of our engineering
personnel from our product development efforts and could harm our relationships
with our customers. The occurrence of these problems could result in the delay
or loss of market acceptance of our products and would likely harm our business.
Defects, integration issues or other performance problems in our products could
result in financial or other damages to our customers or could lessen market
acceptance of our products. Our customers could also seek and obtain damages
from us for their losses. A product liability claim brought against us, even if
unsuccessful, would likely be time consuming and costly to defend.

STRONG COMPETITION IN THE SEMICONDUCTOR MEMORY MARKET MAY HARM OUR BUSINESS.

     The semiconductor memory market is intensely competitive and has been
characterized by an oversupply of product, price erosion, rapid technological
change, short product life cycles, cyclical market patterns and heightened
foreign and domestic competition. Certain of our competitors offer broader
product lines and have greater financial, technical, marketing, distribution and
other resources than us. We may not be able to compete successfully against any
of these competitors. Our ability to compete successfully in the high
performance memory market depends on factors both within and outside of our
control, including:

     -  real or perceived imbalances in supply and demand;


                                       21
<PAGE>   23

     -  product pricing;

     -  the rate at which OEM customers incorporate our products into their
        systems;

     -  the success of our customers' products;

     -  access to advanced process technologies at competitive prices;

     -  product functionality, performance and reliability;

     -  successful and timely product development;

     -  the supply and cost of wafers;

     -  achievement of acceptable yields of functional die;

     -  the gain or loss of significant customers; and

     -  the nature of our competitors and general economic conditions.

     In addition, we are vulnerable to technology advances utilized by
competitors to manufacture higher performance or lower cost products. We may not
be able to compete successfully in the future as to any of these factors. Our
failure to compete successfully in these or other areas could harm our business.

POTENTIAL INTELLECTUAL PROPERTY CLAIMS AND LITIGATION COULD SUBJECT US TO
SIGNIFICANT LIABILITY FOR DAMAGES AND COULD INVALIDATE OUR PROPRIETARY RIGHTS.

     In the semiconductor industry, it is not unusual for companies to receive
notices alleging infringement of patents or other intellectual property rights
of others. We have been, and from time-to-time expect to be, notified of claims
that we may be infringing patents, maskwork rights or copyrights owned by third
parties. For example, for a number of years we have been corresponding with a
large international semiconductor company regarding potential infringement of
certain of their patents by us and certain of our patents by them. Other
companies may pursue claims against us with respect to the alleged infringement
of patents, maskwork rights, copyrights or other intellectual property owned by
third parties. If it appears necessary or desirable, we may seek licenses under
patents that we are alleged to be infringing. Although patent holders commonly
offer such licenses, licenses may not be offered and the terms of any offered
licenses may not be acceptable to us.

     The failure to obtain a license under a key patent or intellectual property
right from a third party for technology used by us could cause us to incur
substantial liabilities and to suspend the manufacture of the products utilizing
the invention or to attempt to develop non-infringing products, any of which
could materially and adversely affect our business and operating results.
Furthermore, we may become involved in protracted litigation regarding the
alleged infringement by us of third party intellectual property rights or
litigation to assert and protect our patents or other intellectual property
rights. Any litigation relating to patent infringement or other intellectual
property matters could result in substantial cost and diversion of our resources
which could harm our business.

WE HAVE SIGNIFICANT INTERNATIONAL SALES AND RISKS OF OUR INTERNATIONAL
OPERATIONS COULD HARM OUR OPERATING RESULTS.

     In the six months ended March 31, 2001, approximately 55% of our net sales
was attributable to customers located in the United States, 25% was attributable
to customers located in Europe and 20% was attributable to customers located in
Asia. In fiscal 2000, approximately 54% of our net sales was attributable to
customers located in the United States, 23% was attributable to customers
located in Europe and 23% was


                                       22
<PAGE>   24

attributable to customers located in Asia. In fiscal 1999, approximately 52% of
our net sales was attributable to customers located in the United States, 20%
was attributable to customers located in Europe and 28% was attributable to
customers located in Asia. Accordingly, our future operating results will also
depend on general economic conditions in Asia, Europe, and the United States. In
addition, the markets for our products, which are highly cyclical, may not
continue to grow. We anticipate that sales to international customers will
continue to represent a significant percentage of net sales.

     We are subject to the risks of conducting business internationally,
including:

     -  economic conditions in Asia, particularly Taiwan and China;

     -  changes in trade policy and regulatory requirements;

     -  duties, tariffs and other trade barriers and restrictions;

     -  the burdens of complying with foreign laws;

     -  foreign currency fluctuations;

     -  difficulties in collecting foreign accounts receivable; and

     -  political instability.

IF WE NEED TO MAKE PAYMENTS FOR UNUSED WAFER CAPACITY, OUR BUSINESS WILL BE
HARMED.

     We have minimum wafer purchase commitments with some of our foundry
partners in exchange for wafer capacity commitments. Should we fail to
reschedule or assign unneeded capacity, we will be required to make payments for
the unused capacity and our business would be harmed. We have agreed to make
certain annual purchases totaling, in aggregate, approximately $4.8 million
through 2001 from TSMC for additional capacity above the annual base capacity.
Wafer purchases in any given year are first applied to the base capacity and
then to our $4.8 million obligation. As a result, we could be forced to pay up
to $4.8 million even if we do not purchase the base capacity and additional
capacity for which we have contracted.

WE DEPEND ON OUR ABILITY TO ATTRACT AND RETAIN OUR KEY TECHNICAL AND MANAGEMENT
PERSONNEL.

     Our success depends upon the continued service of key technical and
management personnel, including Jimmy S.M. Lee, Chairman and Chief Executive
Officer, and on our ability to continue to attract, retain and motivate
qualified personnel, particularly experienced circuit designers and process
engineers. The competition for such employees is intense. We have no employment
contracts or key person life insurance policies with or for any of our executive
officers. The loss of the service of one or more of our key personnel could
materially and adversely affect our business and operating results.

OUR STOCK PRICE IS EXPECTED TO BE VOLATILE.

     The trading price of our common stock has been and is expected to be
subject to wide fluctuations in response to:

     -  quarter-to-quarter variations in our operating results;

     -  comments or recommendations issued by analysts who follow us, our
        competitors or the semiconductor industry and other events or factors;

     -  aggregate valuations and movement of stocks in the broader semiconductor
        industry;


                                       23
<PAGE>   25

     -  announcements of new products, strategic relationships or acquisitions
        by us or our competitors;

     -  increases or decreases in wafer capacity;

     -  general conditions or cyclicality in the semiconductor industry or the
        end markets that we serve;

     -  governmental regulations, trade laws and import duties;

     -  litigation;

     -  new or revised earnings estimates;

     -  announcements of technological innovations by us or our competitors;

     -  additions or departures of senior management; and

     -  other events or factors many of which are beyond our control.

In addition, stock markets have experienced extreme price and trading volume
volatility in recent years. This volatility has had a substantial effect on the
market prices of securities of many high technology companies for reasons
frequently unrelated to the operating performance of the specific companies.
These broad market fluctuations may adversely affect the market price of our
common stock.

ITEM 3.  FINANCIAL MARKET RISK

        We develop products in the United States and sell them worldwide. As a
result, our financial results could be affected by factors such as changes in
foreign currency exchange rates or weak economic conditions in foreign markets.
Since our sales are currently priced in U.S. dollars and are translated to local
currency amounts, a strengthening of the dollar could make our products less
competitive in foreign markets. Interest income is sensitive to changes in the
general level of U.S. interest rates, particularly since our investments are in
short-term instruments calculated at variable rates.

        We established policies and business practices regarding our investment
portfolio to preserve principal while obtaining reasonable rates of return
without significantly increasing risk. We place investments with high credit
quality issuers according to our investment policy. We do not use derivative
financial instruments in our investment portfolio. All investments are carried
at cost, which approximates market value. Due to the short-term nature of our
investments and the immaterial amount of our debt obligation, we believe that
there is no material exposure to interest fluctuation. Therefore, no
accompanying table has been provided.

                           PART II. OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

     In April 1998, the U.S. Department of Commerce ("DOC") published an
antidumping duty order on imports of SRAMs from Taiwan, from where we currently
import a majority of our SRAMs. As a consequence of this antidumping duty order,
we are required to post a cash deposit on imports of Taiwan fabricated SRAM
wafers or devices at the ad valorem rate of 7.56%.

     On April 28, 2000, Micron Technology Inc. ("Micron") requested an
administrative review of our Taiwan fabricated SRAMs for the period from April
1, 1999 through March 31, 2000. For entries during this period, the cash
deposits could be returned to us or, alternatively, we could forfeit amounts
deposited and owe


                                       24
<PAGE>   26

duties and interest in addition to the amounts deposited, depending on results
of the DOC administrative review. The final results of the review are expected
in calendar year 2001 and will establish a new deposit rate for subsequent
entries, which may be higher or lower than the current rate.

     We have retained legal counsel to defend our interests in the antidumping
proceedings. In addition, respondents (including ISSI) have challenged certain
aspects of the antidumping determination in federal court proceedings. On August
29, 2000, pursuant to an appeal by ISSI and other respondents, the U.S. Court of
International Trade affirmed the International Trade Commission ("ITC") decision
to reverse the ITC's earlier ruling supporting the imposition of antidumping
duties and rule instead in favor of respondents. This decision by the Court of
International Trade has been appealed by Micron to the Federal Circuit Court of
Appeals. If such appeal is not successful, the antidumping case will be
terminated, the order will be revoked, and we will be entitled to a full refund
of cash deposits. Pending resolution of the appeal, the DOC will continue to
administer the antidumping order.

     Duties calculated and assessed by the government could have a material
adverse affect on our gross margins and profits. Any reviews or proceedings
might not mitigate or eliminate antidumping duties.

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

The Company's Annual Meeting of Stockholders was held on Tuesday, February 6,
2001 at 3:00 p.m., local time, in San Jose, California.

        (a) The following nominees for Directors were elected. Each person
elected as a Director will serve until the next annual meeting of stockholders
or until such person's successor is elected and qualified:

<TABLE>
<CAPTION>
                                              Votes                 Votes
          Name of Nominee                    in Favor              Withheld
          ---------------                    --------              --------
<S>                                         <C>                     <C>
          Jimmy S.M. Lee                    22,837,689              982,910
          Thomas C. Endicott                22,839,731              980,868
          Pauline Lo Alker                  22,839,773              980,826
          Lip-Bu Tan                        22,841,744              978,855
          Hide L. Tanigami                  22,841,144              979,455
          Chun Win Wong                     19,423,165            4,397,434
</TABLE>

        (b) The Company's stockholders approved an amendment to the Company's
1993 Employee Stock Purchase Plan to increase by 250,000 shares to an aggregate
of 1,950,000 shares the number of shares reserved for grant thereunder, with
23,242,991 votes in favor and 541,672 votes against.

        (c) The Company's stockholders approved an amendment to the Company's
1998 Stock Plan to increase by 500,000 shares the number of shares reserved for
grant thereunder, with 13,969,917 votes in favor and 9,814,342 votes against.

        (d) The Company's stockholders the ratification and appointment of Ernst
& Young, LLP as independent auditors of the Company for the fiscal year ending
September 30, 2001, with 23,772,395 votes in favor, and 24,117 votes against.

ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K

        (a) The following exhibits are filed as a part of this report.

            Exhibit 3.3 Bylaws of Integrated Silicon Solution, Inc., as amended.

        (b) Reports on Form 8-K.

            The registrant did not file any reports on Form 8-K during the
quarter ended March 31, 2001.



                                       25
<PAGE>   27


                                   SIGNATURES


Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                         Integrated Silicon Solution, Inc.
                                         --------------------------------------
                                         (Registrant)


Dated: May 15, 2001                      /s/ Gary L. Fischer
                                         --------------------------------------
                                         Gary L. Fischer
                                         President, Chief Operating Officer
                                         and Chief Financial Officer
                                         (Principal Financial and
                                         Accounting Officer)







                                       26
<PAGE>   28


                                 EXHIBIT INDEX


<TABLE>
<CAPTION>
       Exhibit                 Description
       -------                 -----------
<S>              <C>
         3.3     Bylaws of Integrated Silicon Solution, Inc., as amended.
</TABLE>