EX-10.7



 Exhibit 10.7 

Execution Version 

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT AND 

FIRST AMENDMENT TO WARRANTS 

This FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT AND FIRST AMENDMENT TO WARRANTS (this “Amendment”), dated as
of April 10, 2018 (the “Amendment Effective Date”), is entered into by and among Tricida, Inc. (the “Borrower”), Hercules Capital, Inc. (“Hercules Capital”), a Maryland corporation, in its
capacity as administrative agent and collateral agent for itself and the Lender (in such capacity, together with its successors and assigns in such capacity, the “Agent”), and Hercules Technology III, L.P. (“Hercules
Technology”), a Delaware limited partnership. 
 WHEREAS, the Borrower, the Lender and Agent are parties to that certain
Loan and Security Agreement dated as of February 28, 2018 (as amended, modified or supplemented from time to time, the “Loan Agreement”); 

WHEREAS, the Borrower and Hercules Capital entered into that certain Warrant Agreement (“Warrant One”) dated as of
February 28, 2018; 
 WHEREAS, the Borrower and Hercules Technology (with Hercules Capital, the
“Warrantholders”) entered into that certain Warrant Agreement (“Warrant Two”) dated as of February 28, 2018 (collectively, with Warrant One, the “Warrants,” and with the Loan Agreement and
Warrant One, the “Agreements”); 
 WHEREAS, the Borrower has requested certain modifications to the Agreements; and

 WHEREAS, the Required Lenders, as defined in the Loan Agreement, and Agent are willing to amend the Loan Agreement and the
Warrantholders are willing to amend the Warrants in accordance with and subject to the terms and conditions set forth herein. 
 NOW,
THEREFORE, in consideration of the foregoing recitals and other good and valuable consideration, the receipt and adequacy of which are hereby acknowledged, and intending to be legally bound, the parties hereto agree as follows: 

SECTION 1 Definitions; Interpretation. 

(a) All capitalized terms used in this Amendment (including in the recitals hereof) and not otherwise defined herein shall have the meanings
assigned to them in the Loan Agreement or the Warrants, as applicable. 
 (b) The rules of interpretation set forth in Section 1.1 of
the Loan Agreement shall be applicable to this Amendment and are incorporated herein by this reference. 
 SECTION 2 Amendments to the Loan Agreement and
the Warrants 
 (a) Amendments to the Loan Agreement  

  
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 (i) Section 1 (Definitions and Rules of Construction). The
definition of “Warrant” in Section 1 is hereby amended and restated in its entirety as follows: 
 “‘Warrant’
means any warrant entered into in connection with the Borrower’s draw of each Term Loan Advance in Tranche 1, Tranche 2, Tranche 3, Tranche 4, and/or Tranche 5, respectively, as set forth in either Exhibit I or Exhibit J, as may be amended,
restated or modified from time to time.” 
 (ii) Section 4.2 (All Advances). Section 4.2 of the Loan
Agreement is hereby amended and restated in its entirety by adding a new subsection (g) as follows: 
 “(g) Borrower and the party
identified on the signature pages to each form of Warrant, as set forth in Exhibit I or Exhibit J, shall have executed a Warrant in connection with each applicable Term Loan Advance.” 

(iii) Table of Addenda, Exhibits and Schedules. In Annex A hereto, insertions of text in the Table of Addenda, Exhibits
and Schedules as amended by this Amendment are indicated by bold, double-underlined text. 
 (iv) Addendum 1 to Loan Agreement, Section
(g) (Redemption Provisions). Section (g) of Addendum 1 to Loan Agreement is hereby amended and restated in its entirety as follows: 

“(g) Redemption Provisions. Notwithstanding any provision to the contrary contained in the Certificate of Incorporation of
Borrower, as amended from time to time (the “Charter”), if, pursuant to the redemption provisions contained in the Charter, Lender is entitled to a redemption of its Warrant, such redemption (in the case of Lender) will be at a price equal
to the redemption price set forth in the Charter (the “Existing Redemption Price”), if such exists. If, however, Lender delivers written notice to Borrower that the then current regulations promulgated under the SBIC Act prohibit payment
of the Existing Redemption Price in the case of an SBIC (or, if applied, the Existing Redemption Price would cause the applicable preferred stock to lose its classification as an “equity security” and Lender has determined that such
classification is unadvisable), the amount Lender will be entitled to receive shall be the greater of (i) fair market value of the securities being redeemed taking into account the rights and preferences of such securities plus any costs and
expenses of the Lender incurred in making or maintaining the Warrant, and (ii) the Existing Redemption Price where the amount of accrued but unpaid dividends payable to the Lender is limited to Borrower’s earnings plus any costs and
expenses of the Lender incurred in making or maintaining the Warrant; provided, however, the amount calculated in subsections (i) or (ii) above shall not exceed the Existing Redemption Price.” 

(v) Exhibit I: Form of Warrant for Hercules Capital, Inc. Exhibit I is hereby added to the Loan Agreement in its entirety as provided in
Annex B hereto. 

  
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 (vi) Exhibit J: Form of Warrant for Hercules Technology III, L.P. Exhibit J is hereby
added to the Loan Agreement in its entirety as provided in Annex C hereto. 
 (b) Amendments to the Warrants 

(i) Section 1 (Grant of the Right to Purchase Common Stock). The definition of “Exercise Price” in
Section 1 is hereby amended and restated in its entirety as follows: 
 “‘Exercise Price’ means the lesser of
(a) if the Company achieves the IPO Milestone, the initial price to the public per share of Common Stock specified in the final prospectus filed with the SEC with respect to the Company’s Initial Public Offering, or (b) the Series D
Conversion Price. In no event shall the Exercise Price be less than the Floor Price.” 
 (ii) Section 1 (Grant of
the Right to Purchase Common Stock). Section 1 is modified to add the following: 
 “Floor Price” means $.20/share
of Common Stock. 
 (iii) Section 1 (Grant of the Right to Purchase Common Stock). The definition of “Warrant
Coverage” in Section 1 of Warrant One is hereby amended and restated in its entirety as follows: 
 “‘Warrant
Coverage’ means Three Hundred Thousand Dollars ($300,000.00).” 
 (iv) Section 1 (Grant of the Right to
Purchase Common Stock). The definition of “Warrant Coverage” in Section 1 of Warrant Two is hereby amended and restated in its entirety as follows: 

“‘Warrant Coverage’ means Two Hundred Thousand Dollars ($200,000.00).” 

(v) Section 2 (Term of the Agreement). Section 2 is hereby amended and restated in its entirety as follows: 

“Except as otherwise provided for herein, the term of this Agreement and the right to purchase Common Stock as granted herein (the
“Warrant”) shall commence on the Effective Date and shall be exercisable for a period ending upon the earliest to occur of (i) February 28, 2025; (ii) three (3) years after the Initial Public Offering; and
(iii) immediately prior to the closing of a Merger Event (the “Exercise Period”).” 
 (c) References within the
Loan Agreement and the Warrants. Each reference in the Loan Agreement and the Warrants to “this Agreement” and the words “hereof,” “herein,” “hereunder,” or words of like import, shall mean and be a
reference to the Loan Agreement or the Warrants, as applicable, as amended by this Amendment. 
 SECTION 3 Conditions of Effectiveness. The
effectiveness of Section 2 of this Amendment shall be subject to the satisfaction of each of the following conditions precedent: 

  
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 (a) Fees and Expenses. The Borrower shall have paid (i) all attorney fees and other
costs and expenses then due in accordance with Section 5(e), and (ii) all other fees, costs and expenses, if any, due and payable as of the Amendment Effective Date under the Loan Agreement. 

(b) This Amendment. Agent shall have received this Amendment, executed by Agent, the Lender and the Borrower. 

(c) Officer’s Certificates. Agent shall have received certified copy of resolutions of Borrower’s board of directors
evidencing approval of this Amendment and other transactions contemplated herein. 
 (d) Representations and Warranties; No Default.
On the Amendment Effective Date, after giving effect to the amendment of the Loan Agreement contemplated hereby: 
 (i) The representations
and warranties contained in Section 4 shall be true and correct on and as of the Amendment Effective Date as though made on and as of such date; and 

(ii) There exist no Events of Default or events that with the passage of time would result in an Event of Default. 

SECTION 4 Representations and Warranties. To induce Agent and Lender to enter into this Amendment, Borrower hereby confirms, as of the date hereof,
(a) that the representations and warranties made by it in Section 5 of the Loan Agreement and in the other Loan Documents are true and correct in all material respects; provided, however, that such materiality qualifier shall
not be applicable to any representations and warranties that already are qualified or modified by materiality in the text thereof; (b) that there has not been and there does not exist a Material Adverse Change; and (c) that the information
included in the Perfection Certificate delivered to Agent on the Effective Date remains true and correct. For the purposes of this Section 4, (i) each reference in Section 5 of the Loan Agreement to “this
Agreement,” and the words “hereof,” “herein,” “hereunder,” or words of like import in such section, shall mean and be a reference to the Loan Agreement as amended by this Amendment, and (ii) any
representations and warranties which relate solely to an earlier date shall not be deemed confirmed and restated as of the date hereof (provided that such representations and warranties shall be true, correct and complete as of such earlier date).

 SECTION 5 Miscellaneous. 
 (a)
Loan Documents Otherwise Not Affected; Reaffirmation. Except as expressly amended pursuant hereto or referenced herein, the Loan Agreement and the other Loan Documents shall remain unchanged and in full force and effect and are hereby
ratified and confirmed in all respects. The Lender’s and Agent’s execution and delivery of, or acceptance of, this Amendment shall not be deemed to create a course of dealing or otherwise create any express or implied duty by any of them
to provide any other or further amendments, consents or waivers in the future. Borrower hereby reaffirms the grant of security under Section 3.1 of the Loan Agreement and hereby reaffirms that such grant of security in the Collateral secures
all Secured Obligations under the Loan Agreement and the other Loan Documents. 

  
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 (b) Conditions. For purposes of determining compliance with the conditions specified in
Section 3, each Lender that has signed this Amendment shall be deemed to have consented to, approved or accepted or to be satisfied with, each document or other matter required thereunder to be consented to or approved by
or acceptable or satisfactory to a Lender unless Agent shall have received notice from such Lender prior to the Amendment Effective Date specifying its objection thereto. 

(c) Release. In consideration of the agreements of Agent and each Lender contained herein and for other good and valuable consideration,
the receipt and sufficiency of which are hereby acknowledged, Borrower, on behalf of itself and its successors, assigns, and other legal representatives, hereby fully, absolutely, unconditionally and irrevocably releases, remises and forever
discharges Agent and each Lender, and its successors and assigns, and its present and former shareholders, affiliates, subsidiaries, divisions, predecessors, directors, officers, attorneys, employees, agents and other representatives (Agent, Lenders
and all such other persons being hereinafter referred to collectively as the “Releasees” and individually as a “Releasee”), of and from all demands, actions, causes of action, suits, covenants, contracts,
controversies, agreements, promises, sums of money, accounts, bills, reckonings, damages and any and all other claims, counterclaims, defenses, rights of set-off, demands and liabilities whatsoever of every
name and nature, known or unknown, suspected or unsuspected, both at law and in equity, which Borrower, or any of its successors, assigns, or other legal representatives may now or hereafter own, hold, have or claim to have against the Releasees or
any of them for, upon, or by reason of any circumstance, action, cause or thing whatsoever which arises at any time on or prior to the day and date of this Amendment for or on account of, or in relation to, or in any way in connection with the Loan
Agreement, or any of the other Loan Documents or transactions thereunder or related thereto. Borrower understands, acknowledges and agrees that the release set forth above may be pleaded as a full and complete defense and may be used as a basis for
an injunction against any action, suit or other proceeding which may be instituted, prosecuted or attempted in breach of the provisions of such release. Borrower agrees that no fact, event, circumstance, evidence or transaction which could now be
asserted or which may hereafter be discovered shall, to the fullest extent of the law, affect in any manner the final, absolute and unconditional nature of the release set forth above. 

(d) No Reliance. Borrower hereby acknowledges and confirms to Agent and the Lender that Borrower is executing this Amendment on the
basis of its own investigation and for its own reasons without reliance upon any agreement, representation, understanding or communication by or on behalf of any other Person. 

(e) Costs and Expenses. Borrower agrees to pay to Agent on the Amendment Effective Date the out-of-pocket costs and expenses of Agent and the Lenders party hereto, and the fees and disbursements of counsel to Agent and the Lenders party hereto (including allocated costs of internal counsel), in
connection with the negotiation, preparation, execution and delivery of this Amendment and any other documents to be delivered in connection herewith on the Amendment Effective Date or after such date. 

(f) Binding Effect. This Amendment binds and is for the benefit of the successors and permitted assigns of each party. 

  
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 (g) Governing Law. This Amendment and the other Loan Documents shall be governed by, and
construed and enforced in accordance with, the laws of the State of California, excluding conflict of laws principles that would cause the application of laws of any other jurisdiction. 

(h) Complete Agreement; Amendments. This Amendment and the Loan Documents represent the entire agreement about this subject matter and
supersede prior negotiations or agreements with respect to such subject matter. All prior agreements, understandings, representations, warranties, and negotiations between the parties about the subject matter of this Amendment and the Loan Documents
merge into this Amendment and the Loan Documents. 
 (i) Severability of Provisions. Each provision of this Amendment is severable
from every other provision in determining the enforceability of any provision. 
 (j) Counterparts. This Amendment may be executed in
any number of counterparts and by different parties on separate counterparts, each of which, when executed and delivered, is an original, and all taken together, constitute one Amendment. Delivery of an executed counterpart of a signature page of
this Amendment by facsimile, portable document format (.pdf) or other electronic transmission will be as effective as delivery of a manually executed counterpart hereof. 

(k) Loan Documents. This Amendment shall constitute a Loan Document. 

[Balance of Page Intentionally Left Blank; Signature Pages Follow] 

  
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 IN WITNESS WHEREOF, the parties hereto have duly executed this Amendment, as of the date first
above written. 
  

			
	BORROWER:
	
	TRICIDA, INC.
	
	Signature: /s/ Geoffrey Parker                            
	Print Name: Geoffrey Parker
	Title: Chief Financial Officer
	
	AGENT, LENDER and WARRANTHOLDER:
	
	HERCULES CAPITAL, INC.
	
	Signature: /s/ Zhuo
Huang                                
	Print Name: Zhuo Huang
	Title: Associate General Counsel
	
	LENDER and WARRANTHOLDER:
	
	HERCULES TECHNOLOGY III, L.P.,
	a Delaware limited partnership
	
	 By: Hercules Technology SBIC Management, LLC,

its General Partner

	
	 By: Hercules Capital, Inc.,
 its
Manager

		
	 By:
	 	/s/ Zhuo Huang                                
	 Name:
	 	Zhuo Huang
	 Its:
	 	Associate General Counsel


 [Signature Page to First Amendment to Loan and Security Agreement and First Amendment to Warrants]








 ANNEX A 

Table of Addenda, Exhibits and Schedules 
  

	Addendum 1:	SBA Provisions 

  

	Exhibit A:	Advance Request 


	 	Attachment to Advance Request 

  

	Exhibit B:	Term Note 

  

	Exhibit C:	Name, Locations, and Other Information for Borrower 

  

	Exhibit D:	[Reserved] 

  

	Exhibit E:	Borrower’s Deposit Accounts and Investment Accounts 

  

	Exhibit F:	Compliance Certificate 

  

	Exhibit G:	Joinder Agreement 

  

	Exhibit H:	ACH Debit Authorization Agreement 

  

	Exhibit I:	Form of Warrant for Hercules Capital, Inc. 

  

	Exhibit J:	Form of Warrant for Hercules Technology III, L.P. 

  

	Schedule 1	Subsidiaries 


	Schedule 1.1	Commitments 


	Schedule 1A	Existing Permitted Indebtedness 


	Schedule 1B	Existing Permitted Investments 


	Schedule 1C	Existing Permitted Liens 


	Schedule 5.3	Consents, Etc. 


	Schedule 5.5	Actions Before Governmental Authorities 


	Schedule 5.8	Tax Matters 


	Schedule 5.9	Intellectual Property Claims 


	Schedule 5.10	Intellectual Property 


	Schedule 5.11	Borrower Products 


	Schedule 5.14	Capitalization 








 ANNEX B 

EXHIBIT I 
 FORM OF
WARRANT FOR HERCULES CAPITAL, INC. 
 THIS WARRANT, AND THE SECURITIES ISSUABLE UPON THE EXERCISE OF THIS WARRANT, HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY STATE SECURITIES LAWS. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF
COUNSEL (WHICH MAY BE COMPANY COUNSEL) REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT, OR ANY APPLICABLE STATE SECURITIES LAWS. 

WARRANT AGREEMENT 
 To Purchase
Shares of Common Stock of 
 Tricida, Inc. 

Dated as of [    ] (the “Effective Date”) 

WHEREAS, Tricida, Inc., a Delaware corporation, has entered into a Loan and Security Agreement, dated as of February 28, 2018 (the “Loan
Agreement”), with Hercules Capital, Inc., a Maryland corporation, in its capacity as administrative and collateral agent, Hercules Capital, Inc. (the “Warrantholder”) and the other lender parties thereto; 

WHEREAS, the Company (as defined below) desires to grant to the Warrantholder, in consideration for, among other things, the financial accommodations provided
for in the Loan Agreement, the right to purchase shares of Common Stock (as defined below) pursuant to this Warrant Agreement (the “Agreement”); 

NOW, THEREFORE, in consideration of the Warrantholder executing and delivering the Loan Agreement and providing the financial accommodations contemplated
therein, and in consideration of the mutual covenants and agreements contained herein, the Company and the Warrantholder agree as follows: 
 SECTION 1.
GRANT OF THE RIGHT TO PURCHASE COMMON STOCK. 
 For value received, the Company hereby grants to the Warrantholder, and the Warrantholder is entitled,
upon the terms and subject to the conditions hereinafter set forth, to subscribe for and purchase, from the Company, an aggregate number of fully paid and non-assessable shares of Common Stock equal to the
quotient derived by dividing (a) the Warrant Coverage (as defined below) by (b) the Exercise Price (as defined below). The Exercise Price of such shares are subject to adjustment as provided in Section 8. As used herein, the following
terms shall have the following meanings: 
 “Act” means the Securities Act of 1933, as amended. 

“Charter” means the Company’s Certificate of Incorporation, as may be amended from time to time. 

“Common Stock” means the Company’s common stock, $0.001 par value per share. 

“Company” means Tricida, Inc., a Delaware corporation. 

  
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 “Exercise Price” means the lesser of (a) if the Company achieves the IPO
Milestone, the initial price to the public per share of Common Stock specified in the final prospectus filed with the SEC with respect to the Company’s Initial Public Offering, or (b) the Series D Conversion Price. In no event shall the
Exercise Price be less than the Floor Price.” 
 “Floor Price” means $.20/share of Common Stock. 

“Initial Public Offering” means the initial underwritten public offering of the Common Stock pursuant to a registration
statement under the Act, which registration statement has been declared effective by the Securities and Exchange Commission (“SEC”). 

“IPO Milestone” means receipt by the Company, prior to December 15, 2018, of at least One Hundred Million Dollars
($100,000,000.00) in aggregate proceeds (net of underwriting discounts and commissions) from an Initial Public Offering. 
 “Merger
Event” means any sale, lease, exclusive license or other transfer of all or substantially all assets of the Company or any merger or consolidation involving the Company in which the Company is not the surviving entity, or in which the
outstanding shares of the Company’s capital stock are otherwise converted into or exchanged for shares of common stock, preferred stock, other securities or property of another entity; other than any such consolidation, merger or reorganization
in which the shares of capital stock of the Company immediately prior to such consolidation, merger or reorganization, continue to represent a majority of the voting power of the surviving entity (or, if the surviving entity is a wholly owned
subsidiary, its parent) immediately after such consolidation, merger or reorganization (provided that, all shares of Common Stock issuable upon exercise of options or warrants outstanding immediately prior to such consolidation or merger or upon
conversion of convertible securities outstanding immediately prior to such merger or consolidation shall be deemed to be outstanding immediately prior to such merger or consolidation and, if applicable, converted or exchanged in such merger or
consolidation on the same terms as the actual outstanding shares of capital stock are converted or exchanged). 
 “Preferred
Stock” means the Company’s Series D preferred stock, $0.001 par value per share, as presently constituted, and, to the extent provided in Section 8(b), any other stock into or for which such Preferred Stock may be converted or
exchanged. 
 “Purchase Price” means, with respect to any exercise of this Agreement, an amount equal to the Exercise Price
as of the relevant time multiplied by the number of shares of Common Stock requested to be exercised under this Agreement pursuant to such exercise. 

“Series D Conversion Price” has the meaning set forth in the Charter. 

“Warrant Coverage” means [Three Hundred Thousand Dollars ($300,000.00)]1
[1.20% of such amount advanced under Tranche 2, Tranche 3, Tranche 4 or Tranche 5 (as defined and set forth in the Loan Agreement), as applicable to the tranche under which the Agreement was entered into by the parties hereto in connection with the
Term Loan Advance (as defined in the Loan
 Agreement)]2. 
 SECTION 2. TERM OF THE AGREEMENT.

 Except as otherwise provided for herein, the term of this Agreement and the right to purchase Common Stock as granted herein (the
“Warrant”) shall commence on the Effective Date and shall be exercisable for a period ending upon the earliest to occur of (i) February 28, 2025; (ii) three (3) years after the Initial Public Offering; and
(iii) immediately prior to the closing of a Merger Event (the “Exercise Period”). 
  

	1 	Note: Only Tranche 1. 


	2 	Note: Warrantholder to complete based off of applicable Tranche. 


  
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 SECTION 3. EXERCISE OF THE PURCHASE RIGHTS. 

(a) Exercise. The purchase rights set forth in this Agreement are exercisable by the Warrantholder, in whole or in part, at any time, or
from time to time, prior to the expiration of the Exercise Period, by tendering to the Company at its principal office a notice of exercise in the form attached hereto as Exhibit I (the “Notice of Exercise”), duly completed
and executed. Promptly upon receipt of the Notice of Exercise and the payment of the Purchase Price in accordance with the terms set forth below, and in no event later than five (5) days thereafter, the Company shall issue to the Warrantholder
a certificate for the number of shares of Common Stock purchased and shall execute the acknowledgment of exercise in the form attached hereto as Exhibit II (the “Acknowledgment of Exercise”) indicating the number of shares
which remain subject to future purchases under this Warrant, if any. 
 The Purchase Price may be paid at the Warrantholder’s election either
(i) by cash or check, or (ii) by surrender of all or a portion of the Warrant for shares of Common Stock to be exercised under this Agreement and, if applicable, an amended Agreement representing the remaining number of shares purchasable
hereunder, as determined below (“Net Issuance”). If the Warrantholder elects the Net Issuance method, the Company will issue shares of Common Stock in accordance with the following formula: 

X = Y(A-B) 

A 
  

					
	 Where:
	  	X =	  	the number of shares of Common Stock to be issued to the Warrantholder.
			
		  	Y =	  	the number of shares of Common Stock requested to be purchased under this Agreement.
			
		  	A =	  	the fair market value of one (1) share of Common Stock at the time of issuance of such shares of Common Stock.
			
		  	B =	  	the Exercise Price.

 For purposes of the above calculation, current fair market value of Common Stock shall mean with respect to each share of
Common Stock: 
 (i) if the exercise is in connection with an Initial Public Offering, and if the Company’s Registration Statement
relating to such Initial Public Offering has been declared effective by the SEC, then the fair market value per share shall be the initial “Price to Public” of the Common Stock specified in the final prospectus with respect to the
offering; 
 (ii) if the exercise is after, and not in connection with an Initial Public Offering, and: 

(A) if the Common Stock is traded on a securities exchange, the fair market value shall be deemed to be the average of the
closing prices over a five (5) trading day period ending three (3) days before the day the current fair market value of the securities is being determined; or 

(B) if the Common Stock is traded
over-the-counter, the fair market value shall be deemed to be the average of the closing bid and asked price quoted on the NASDAQ system (or similar system) over the
five (5) trading day period ended three (3) days before the day the current fair market value of the securities is being determined; 

  
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 (iii) if at any time the Common Stock is not listed on any securities exchange or quoted in the
NASDAQ National Market or the over-the-counter market, the current fair market value of Common Stock shall be the highest price per share which the Company could
reasonably expect to obtain from a willing buyer (not a current employee or director) for shares of Common Stock sold by the Company, from authorized but unissued shares, as determined in good faith by its Board of Directors (provided that if the
Company is then in possession of a recent valuation of the Company’s Common Stock, the Board of Directors may rely on such valuation), unless the Notice of Exercise is delivered in connection with a Merger Event, in which case the fair market
value of Common Stock shall be deemed to be the per share value received by the holders of the Company’s Common Stock on a common equivalent basis pursuant to such Merger Event. 

Upon partial exercise by either cash or Net Issuance, the Company shall promptly issue an amended Agreement representing the remaining number of shares
purchasable hereunder. All other terms and conditions of such amended Agreement shall be identical to those contained herein, including, but not limited to the Effective Date hereof and Exercise Period. 

(b) Exercise Prior to Expiration. To the extent this Agreement is not previously exercised as to all shares of Common Stock subject
hereto, and if the fair market value of one share of the Common Stock is greater than the Exercise Price then in effect, this Agreement shall be deemed automatically exercised pursuant to Section 3(a) (even if not surrendered) as of the last
day of the Exercise Period. For purposes of such automatic exercise, the fair market value of one share of the Common Stock upon such expiration shall be determined pursuant to Section 3(a). To the extent this Agreement or any portion thereof
is deemed automatically exercised pursuant to this Section 3(b), the Company agrees to promptly notify the Warrantholder of the number of shares of Common Stock, if any, the Warrantholder is to receive by reason of such automatic exercise. 

SECTION 4. RESERVATION OF SHARES. 
 During the term of
this Agreement, the Company will at all times have authorized and reserved a sufficient number of shares of its Common Stock to provide for the exercise of the rights to purchase Common Stock as provided for herein. 

SECTION 5. NO FRACTIONAL SHARES OR SCRIP. 
 No fractional
shares or scrip representing fractional shares shall be issued upon the exercise of this Agreement, but in lieu of such fractional shares, the Company shall make a cash payment therefor equal to such fraction multiplied by the then fair market value
of one share of Common Stock. 
 SECTION 6. NO RIGHTS AS STOCKHOLDER. 

This Agreement does not entitle the Warrantholder to any voting rights or other rights as a stockholder of the Company prior to the exercise of this Agreement.

 SECTION 7. WARRANTHOLDER REGISTRY. 
 The Company
shall maintain a registry showing the name and address of the registered holder of this Agreement. The Warrantholder’s initial address, for purposes of such registry, is set forth below the Warrantholder’s signature on this Agreement. The
Warrantholder may change such address by giving written notice of such changed address to the Company. 
 SECTION 8. ADJUSTMENT RIGHTS. 

The Exercise Price and the number of shares of Common Stock purchasable hereunder are subject to adjustment, as follows: 

  
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 (a) Merger Event. If at any time there shall be a Merger Event, then, as a part of such
Merger Event, lawful provision shall be made so that the Warrantholder shall be entitled to receive, concurrently with the closing of such Merger Event, the number of shares of Common Stock or other securities or property, if any, (collectively,
“Reference Property”) that the Warrantholder would have received in connection with such Merger Event if Warrantholder had exercised this Agreement immediately prior to the Merger Event pursuant to the Net Issuance provisions of
this Warrant Agreement without actually exercising such right. 
 (b) Reclassification of Shares. Except for Merger Events subject to
Section 8(a), if the Company at any time shall, by combination, reclassification, exchange or subdivision of securities or otherwise, change any of the securities as to which purchase rights under this Agreement exist into the same or a
different number of securities of any other class or classes, this Agreement shall thereafter represent the right to acquire such number and kind of securities as would have been issuable as the result of such change with respect to the securities
which were subject to the purchase rights under this Agreement immediately prior to such combination, reclassification, exchange, subdivision or other change. The provisions of this Section 8(b) shall similarly apply to any successive
combination, reclassification, exchange, subdivision or other change. 
 (c) Subdivision or Combination of Shares. If the Company at
any time shall combine or subdivide its Common Stock, (i) in the case of a subdivision, the Exercise Price shall be proportionately decreased and the number of shares of Common Stock issuable hereunder shall be proportionately increased, or
(ii) in the case of a combination, the Exercise Price shall be proportionately increased and the number of shares of Common Stock issuable hereunder shall be proportionately decreased. 

(d) Dividends. If the Company at any time prior to the Initial Public Offering and while this Agreement is outstanding and unexpired
shall: 
 (i) pay a dividend with respect to the Common Stock payable in Common Stock, then the Exercise Price shall be adjusted, from and
after the date of determination of the stockholders entitled to receive such dividend or distribution, to that price determined by multiplying the Exercise Price in effect immediately prior to such date of determination by a fraction (A) the
numerator of which shall be the total number of shares of Common Stock outstanding immediately prior to such dividend or distribution, and (B) the denominator of which shall be the total number of shares of Common Stock outstanding immediately
after such dividend or distribution; or 
 (ii) make any other dividend or distribution with respect to Common Stock, except any dividend or
distribution specifically provided for in any other clause of this Section 8, then, in each such case, provision shall be made by the Company such that the Warrantholder shall receive upon exercise or conversion of this Warrant a proportionate
share of any such dividend or distribution as though it were the holder of the Common Stock as of the record date fixed for the determination of the stockholders of the Company entitled to receive such dividend or distribution. 

(e) [Intentionally omitted]. 

(f) Notice of Adjustments. If prior to Initial Public Offering: (i) the Company shall declare any dividend or distribution upon its
stock, whether in stock, cash, property or other securities; (ii) there shall be any Merger Event; or (iii) there shall be any voluntary dissolution, liquidation or winding up of the Company; then, in connection with each such event, the
Company shall send to the Warrantholder: (A) at least fifteen (15) days’ prior written notice of the date on which the books of the Company shall close or a record shall be taken for such dividend, distribution, subscription rights
(specifying the date on which the holders of Common Stock shall be entitled thereto) or for determining rights to vote in respect of such Merger Event, dissolution, liquidation or winding up; and (B) in the case of any such Merger Event,
dissolution, liquidation or winding up, at least fifteen (15) days’ prior written notice of the date when the same shall take place (and specifying the date on which the holders of Common Stock shall be entitled to exchange their Common
Stock for securities or other property deliverable upon such Merger Event, dissolution, liquidation or winding up). 

  
 13 








 Each such written notice shall be given in accordance with Section 12(g) below and shall set forth, in
reasonable detail, (i) the event requiring the notice, and (ii) if any adjustment is required to be made pursuant to this Section 8, (A) the amount of such adjustment, (B) the method by which such adjustment was calculated,
(C) the adjusted Exercise Price (if the Exercise Price has been adjusted), and (D) the number of shares subject to purchase hereunder after giving effect to such adjustment. 

(g) Timely Notice. Notwithstanding the failure to timely provide any such notice required by Section 8(f) above, the Warrantholder
shall retain the benefit of the applicable notice period notwithstanding anything to the contrary contained in any insufficient notice received by the Warrantholder. 

SECTION 9. REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE COMPANY. 

(a) Reservation of Common Stock. The Common Stock issuable upon exercise of this Agreement has been duly and validly reserved and, when
issued in accordance with the provisions of this Agreement, will be validly issued, fully paid and non-assessable, and will be free of any taxes, liens, charges or encumbrances created by the Company;
provided, that the Common Stock issuable pursuant to this Agreement may be subject to restrictions on transfer under state and/or federal securities laws. The Company has made available to the Warrantholder true, correct and complete copies
of its Charter and current bylaws as of the Effective Date. The issuance of certificates for shares of Common Stock upon exercise of this Agreement shall be made without charge to the Warrantholder for any issuance tax in respect thereof, or other
cost incurred by the Company in connection with such exercise and the related issuance of shares of Common Stock; provided, that the Company shall not be required to pay any tax which may be payable in respect of any transfer and the issuance
and delivery of any certificate in a name other than that of the Warrantholder. 
 (b) Due Authority. The execution and delivery by
the Company of this Agreement and the performance of all obligations of the Company hereunder, including the issuance to the Warrantholder of the right to acquire the shares of Common Stock, have been duly authorized by all necessary corporate
action on the part of the Company. This Agreement: (i) does not violate the Charter or the Company’s current bylaws; (ii) does not contravene any law or governmental rule, regulation or order applicable to the Company; and
(iii) does not contravene any provision of, or constitute a default under, any indenture, mortgage, contract or other instrument to which the Company is a party or by which it is bound. This Agreement constitutes a legal, valid and binding
agreement of the Company, enforceable in accordance with its terms, except (i) as limited by applicable bankruptcy, insolvency, reorganization, moratorium or other laws of general application affecting enforcement of creditors’ rights and
(b) as limited by general principles of equity that restrict the availability of equitable remedies. 
 (c) Consents and
Approvals. No consent or approval of, giving of notice to, registration with, or taking of any other action in respect of any state, federal or other governmental authority or agency is required with respect to the execution, delivery and
performance by the Company of its obligations under this Agreement, except for the filing of notices pursuant to Regulation D under the Act and any filing required by applicable state securities law, which filings will be effective by the time
required thereby. 
 (d) Issued Securities.3 All issued and outstanding shares of
Common Stock, preferred stock or any other securities of the Company have been duly authorized and validly issued and are fully paid and nonassessable. All outstanding shares of Common Stock, preferred stock and any other securities were issued in
full compliance with all federal and state securities laws. In addition, as of the date immediately preceding the date of this Agreement: 

(i) The authorized capital of the Company consists of (A) [134,000,000] shares of Common Stock, of which [9,152,544] shares are
issued and outstanding; (B) [11,398,694] shares of Series A preferred stock, $0.001 par value per share, of which [11,302,758] shares are issued and outstanding and are convertible into an aggregate of [11,302,758] shares of Common Stock at [$0.886]
per share; (C) [32,526,878] shares of 
  
  

	3 	 Note: To be updated with each warrant issuance.




  
 14 








 
Series B preferred stock, $0.001 par value per share, of which [32,526,878] shares are issued and outstanding and are convertible into an aggregate of [32,526,878] shares of Common Stock at
[$0.93] per share; (D) [35,806,451] shares of Series C preferred stock, $0.001 par value per share, of which [35,806,451] shares are issued and outstanding and are convertible into an aggregate of [35,806,451] shares of Common Stock at [$1.55] per
share; and (E) [24,500,000] shares of Series D preferred stock, $0.001 par value per share, of which [24,493,615] shares are issued and outstanding and are convertible into an aggregate of [24,493,615] shares of Common Stock at [$2.35] per share.

 (ii) The Company issued a warrant dated August 9, 2013 exercisable for 95,936 shares of Series A preferred stock.

 (iii) The Company has reserved [18,040,000] shares of Common Stock for issuance under its stock option plan(s), under
which options to purchase [14,115,728] shares of Common Stock are outstanding. Except as noted in clause (i) above, there are no other options, warrants, or other rights presently outstanding to purchase or otherwise acquire any authorized but
unissued shares of the Company’s capital stock of the Company. 
 (iv) No stockholder of the Company has preemptive
rights to purchase new issuances of the Company’s capital stock, other than pursuant to the Investor Rights Agreement (as defined below) and the Loan Agreement. 

(e) Registration Rights. The Company agrees that the shares of Common Stock issued upon exercise of this Warrant shall have the
“Piggyback” and S-3 registration rights pursuant to and as set forth in the Company’s Amended and Restated Investor Rights Agreement, dated November 7, 2017, as amended from time to time
(the “Investor Rights Agreement”) on a pari passu basis with the holders of outstanding shares of Preferred Stock who are parties thereto. The provisions set forth in the Company’s Investor Rights Agreement or similar
agreement relating to such registration rights in effect as of the Effective Date may not be amended, modified or waived without the prior written consent of the Warrantholder unless such amendment, modification or waiver affects the rights
associated with the shares of Common Stock issued and issuable upon exercise hereof in the same manner as such amendment, modification or waiver affects the rights associated with the shares of Common Stock issuable upon conversion of all
outstanding shares of Preferred Stock whose holders are parties thereto. 
 (f) Other Commitments to Register Securities. Except as
set forth in this Agreement or the Investor Rights Agreement, the Company is not, pursuant to the terms of any other agreement currently in existence, under any obligation to register under the Act any of its presently outstanding securities or any
of its securities which may hereafter be issued. 
 (g) Exempt Transaction. Subject to the accuracy of the Warrantholder’s
representations in Section 10, the issuance of the Common Stock upon exercise of this Agreement will constitute a transaction exempt from (i) the registration requirements of Section 5 of the Act, in reliance upon Section 4(2)
thereof, and (ii) the qualification requirements of the applicable state securities laws. 
 (h) Compliance with Rule 144. If the
Warrantholder proposes to sell Common Stock issuable upon the exercise of this Agreement in compliance with Rule 144 promulgated by the SEC, then, upon the Warrantholder’s written request to the Company, the Company shall furnish to the
Warrantholder, within ten days after receipt of such request, a written statement confirming the status of the Company’s compliance with the filing requirements of the SEC as set forth in such Rule, as such Rule may be amended from time to
time. 
 (i) Information Rights. During the term of this Warrant, and only if the Initial Public Offering has not occurred, the
Warrantholder will receive the Company’s audited financial statements in the manner and within the time period provided for with respect to the Major Investors (as defined in the Investor Rights Agreement) pursuant to Section 3.1(b) of the
Investor Rights Agreement; provided, however, that any waiver of such information rights by the Major Investors pursuant to the Investor Rights Agreement shall not act as a waiver of the Warrantholder’s information rights provided
for under this Section 9(i). 

  
 15 








 SECTION 10. REPRESENTATIONS AND COVENANTS OF THE WARRANTHOLDER. 

This Agreement has been entered into by the Company in reliance upon the following representations and covenants of the Warrantholder: 

(a) Investment Purpose. The right to acquire Common Stock is being acquired for investment and not with a view to the sale or
distribution of any part thereof, and the Warrantholder has no present intention of selling or engaging in any public distribution of such rights or the Common Stock except pursuant to an effective registration statement or an exemption from the
registration requirements of the Act. 
 (b) Private Issue. The Warrantholder understands (i) that the Common Stock issuable upon
exercise of this Agreement is not registered under the Act or qualified under applicable state securities laws on the ground that the issuance contemplated by this Agreement will be exempt from the registration and qualifications requirements
thereof, and (ii) that the Company’s reliance on such exemption is predicated on the representations set forth in this Section 10. 

(c) Financial Risk. The Warrantholder has such knowledge and experience in financial and business matters as to be capable of evaluating
the merits and risks of its investment, and has the ability to bear the economic risks of its investment. 
 (d) Risk of No
Registration. The Warrantholder understands that if the Company does not register with the SEC pursuant to Section 12 of the Securities Exchange Act of 1934 (the “1934 Act”), or file reports pursuant to Section 15(d)
of the 1934 Act, or if a registration statement covering the securities under the Act is not in effect when it desires to sell (i) the rights to purchase Common Stock pursuant to this Agreement or (ii) the Common Stock issuable upon
exercise of the right to purchase, it may be required to hold such securities for an indefinite period. The Warrantholder also understands that any sale of (A) its rights hereunder to purchase Common Stock or (B) Common Stock issued or
issuable hereunder which might be made by it in reliance upon Rule 144 under the Act may be made only in accordance with the terms and conditions of that Rule. 

(e) Accredited Investor. The Warrantholder is an “accredited investor” within the meaning of the Securities and Exchange Rule
501 of Regulation D, as presently in effect. 
 (f) For purposes of the rights contemplated by Section 9(e) of this Agreement, upon
exercise of the Warrant, the Warrantholder hereby agrees to be bound by and subject to the terms and provisions of the Investor Rights Agreement as if the Warrantholder was an “Investor” (as defined in the Investor Rights Agreement) party
thereto. 
 (g) Upon exercise of the Warrant, the Warrantholder hereby agrees to be bound by and subject to the terms and provisions of
Section 1.8, Section 2 and Section 3 of the Company’s Amended and Restated Voting Agreement, dated November 7, 2017, as amended from time to time (the “Voting Agreement”), as if the Warrantholder were a
“Stockholder” (as defined in the Voting Agreement) party thereto. 
 SECTION 11. TRANSFERS. 

Subject to compliance with applicable federal and state securities laws, this Agreement and all rights hereunder are transferable, in whole or in part, without
charge to the holder hereof (except for transfer taxes) upon surrender of this Agreement properly endorsed; provided, however, that if there is not then any ongoing Event of Default (as defined in the Loan Agreement), then such
transfer shall be subject to the prior written consent of the Company; provided further, that notwithstanding the foregoing, any such transfer to an Affiliate (as defined in the Loan Agreement) of the Warrantholder shall be allowed at any
time without the 

  
 16 








 
prior written consent of the Company. Each taker and holder of this Agreement, by taking or holding the same, consents and agrees that this Agreement, when endorsed in blank, shall be deemed
negotiable, and that the holder hereof, when this Agreement shall have been so endorsed and its transfer recorded on the Company’s books, shall be treated by the Company and all other persons dealing with this Agreement as the absolute owner
hereof for any purpose and as the person entitled to exercise the rights represented by this Agreement. The transfer of this Agreement shall be recorded on the books of the Company upon receipt by the Company of a notice of transfer in the form
attached hereto as Exhibit III (the “Transfer Notice”), at its principal offices and the payment to the Company of all transfer taxes and other governmental charges imposed on such transfer. Until the Company receives such Transfer
Notice, the Company may treat the registered owner hereof as the owner for all purposes. The Warrantholder may not transfer this Warrant to a competitor of the Company, as reasonably determined by the Board of Directors. 

SECTION 12. MISCELLANEOUS. 
 (a)
Effective Date. The provisions of this Agreement shall be construed and shall be given effect in all respects as if it had been executed and delivered by the Company on the date hereof. This Agreement shall be binding upon any successors or
assigns of the Company. 
 (b) Remedies. In the event of any default hereunder, the
non-defaulting party may proceed to protect and enforce its rights either by suit in equity and/or by action at law, including but not limited to an action for damages as a result of any such default, and/or
an action for specific performance for any default where the Warrantholder will not have an adequate remedy at law and where damages will not be readily ascertainable. The Company expressly agrees that it shall not oppose an application by the
Warrantholder or any other person entitled to the benefit of this Agreement requiring specific performance of any or all provisions hereof or enjoining the Company from continuing to commit any such breach of this Agreement. 

(c) No Impairment of Rights. The Company will not, by amendment of its Charter or through any other means, avoid or seek to avoid the
observance or performance of any of the terms of this Agreement, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate in order to protect the rights
of the Warrantholder against impairment. 
 (d) Additional Documents. The Company, upon execution of this Agreement, shall provide the
Warrantholder with a certified copy of resolutions of the Company’s board of directors evidencing approval of this Agreement and the reservation of the shares of Common Stock issuable upon exercise of the Warrant. Prior to the Initial Public
Offering, the Company shall also supply documentation reasonably requested by the Warrantholder to evaluate whether to exercise this Warrant, including without limitation, (i) any merger/purchase/asset sale agreement and related documents and
estimated payout allocations to each of the respective stockholders, warrant and option holders in connection with a Merger Event, (ii) the most recent capitalization tables, 409A valuations (if any), and board determination of share value
(including any waterfall or per share allocations provided to the stockholders), and (iii) most recent Charter. 
 (e)
Attorney’s Fees. In any litigation, arbitration or court proceeding between the Company and the Warrantholder relating hereto, the prevailing party shall be entitled to attorneys’ fees and expenses and all costs of proceedings
incurred in enforcing this Agreement. For the purposes of this Section 12(e), attorneys’ fees shall include without limitation fees incurred in connection with the following: (i) contempt proceedings; (ii) discovery; (iii) any
motion, proceeding or other activity of any kind in connection with an insolvency proceeding; (iv) garnishment, levy, and debtor and third party examinations; and (v) post-judgment motions and proceedings of any kind, including without
limitation any activity taken to collect or enforce any judgment. 
 (f) Severability. In the event any one or more of the provisions
of this Agreement shall for any reason be held invalid, illegal or unenforceable, the remaining provisions of this Agreement shall be unimpaired, and the invalid, illegal or unenforceable provision shall be replaced by a mutually acceptable valid,
legal and enforceable provision, which comes closest to the intention of the parties underlying the invalid, illegal or unenforceable provision. 

  
 17 








 (g) Notices. Except as otherwise provided herein, any notice, demand, request, consent,
approval, declaration, service of process or other communication that is required, contemplated, or permitted under this Agreement or with respect to the subject matter hereof shall be in writing, and shall be deemed to have been validly served,
given, delivered, and received upon the earlier of: (i) the day of transmission by electronic mail or hand delivery if transmission or delivery occurs on a business day at or before 5:00 pm in the time zone of the recipient, or, if transmission
or delivery occurs on a non-business day or after such time, the first business day thereafter, or the first business day after deposit with an overnight express service or overnight mail delivery service; or
(ii) the third (3rd) calendar day after deposit in the United States mails, with proper first class postage prepaid, and shall be addressed to the party to be notified as follows: 

If to the Warrantholder: 

HERCULES CAPITAL, INC. 

Legal Department 

Attention: Chief Legal Officer and Himani Bhalla 

400 Hamilton Avenue, Suite 310 

Palo Alto, CA 94301 

Telephone: 650-289-3060 

with a copy to (which shall not constitute notice): 

LATHAM & WATKINS LLP 

Attention: Haim Zaltzman 

140 Scott Drive 

Menlo Park, CA 94025 

Telephone: 650-328-4600 

If to the Company: 
 TRICIDA,
INC. 
 Attention: Legal Department 

7000 Shoreline Court, Suite 201 

South San Francisco, CA 94080 

Telephone: (415) 988-2420 

with a copy to (which shall not constitute notice): 

SIDLEY AUSTIN LLP 

Attention: Geoffrey W. Levin 

787 Seventh Avenue 

New York, NY 10019 

Telephone: 212-839-5776 

or to such other address as each party may designate for itself by like notice. 

  
 18 








 (h) Entire Agreement; Amendments. This Agreement constitutes the entire agreement and
understanding of the parties hereto in respect of the subject matter hereof, and supersedes and replaces in their entirety any prior proposals, term sheets, letters, negotiations or other documents or agreements, whether written or oral, with
respect to the subject matter hereof (including the Warrantholder’s proposal letter dated January 19, 2018). None of the terms of this Agreement may be amended except by an instrument executed by each of the parties hereto. 

(i) Headings. The various headings in this Agreement are inserted for convenience only and shall not affect the meaning or
interpretation of this Agreement or any provisions hereof. 
 (j) No Strict Construction. The parties hereto have participated jointly
in the negotiation and drafting of this Agreement. In the event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties hereto and no presumption or burden of proof shall
arise favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement. 
 (k) No Waiver. No omission
or delay by the Warrantholder at any time to enforce any right or remedy reserved to it, or to require performance of any of the terms, covenants or provisions hereof by the Company at any time designated, shall be a waiver of any such right or
remedy to which the Warrantholder is entitled, nor shall it in any way affect the right of the Warrantholder to enforce such provisions thereafter. 

(l) Survival. All agreements, representations and warranties contained in this Agreement or in any document delivered pursuant hereto
shall be for the benefit of the Warrantholder or Company, as applicable, and shall survive the execution and delivery of this Agreement and the expiration or other termination of this Agreement. 

(m) Governing Law. This Agreement has been negotiated and delivered to Warrantholder in the State of California, and shall have been
accepted by the Warrantholder in the State of California. Delivery of Common Stock to the Warrantholder by the Company under this Agreement is due in the State of California. This Agreement shall be governed by, and construed and enforced in
accordance with, the laws of the State of California, excluding conflict of laws principles that would cause the application of laws of any other jurisdiction. 

(n) Consent to Jurisdiction and Venue. All judicial proceedings arising in or under or related to this Agreement may be brought in any
state or federal court of competent jurisdiction located in the State of California. By execution and delivery of this Agreement, each party hereto generally and unconditionally: (a) consents to nonexclusive personal jurisdiction in San Mateo
County, State of California; (b) waives any objection as to jurisdiction or venue in San Mateo County, State of California; (c) agrees not to assert any defense based on lack of jurisdiction or venue in the aforesaid courts; and
(d) irrevocably agrees to be bound by any judgment rendered thereby in connection with this Agreement or the other Loan Documents. Service of process on any party hereto in any action arising out of or relating to this Agreement shall be
effective if given in accordance with the requirements for notice set forth in Section 12(g), and shall be deemed effective and received as set forth in Section 12(g). Nothing herein shall affect the right to serve process in any other
manner permitted by law or shall limit the right of either party to bring proceedings in the courts of any other jurisdiction. 
 (o)
Mutual Waiver of Jury Trial/ Judicial Reference. 
 (i) Because disputes arising in connection with complex financial transactions
are most quickly and economically resolved by an experienced and expert Person and the parties wish applicable state and federal laws to apply (rather than arbitration rules), the parties desire that their disputes be resolved by a judge applying
such applicable laws. EACH OF THE COMPANY AND THE WARRANTHOLDER SPECIFICALLY WAIVES ANY RIGHT IT MAY HAVE TO TRIAL BY JURY OF ANY CAUSE OF ACTION, CLAIM, CROSS-CLAIM, COUNTERCLAIM, THIRD PARTY CLAIM OR ANY OTHER CLAIM (COLLECTIVELY,
“CLAIMS”) ASSERTED BY THE COMPANY AGAINST THE WARRANTHOLDER OR ITS ASSIGNEE OR BY THE WARRANTHOLDER OR ITS ASSIGNEE AGAINST THE COMPANY. This waiver extends to all such Claims, including Claims that involve Persons


  
 19 








 
other than Company and Warrantholder; Claims that arise out of or are in any way connected to the relationship between the Company and the Warrantholder; and any Claims for damages, breach of
contract, tort, specific performance, or any equitable or legal relief of any kind, arising out of this Agreement. 
 (ii) If the waiver of
jury trial set forth in Section 12(o)(i) above is ineffective or unenforceable, the parties agree that all Claims shall be resolved by reference to a private judge sitting without a jury, pursuant to California Code of Civil Procedure
Section 638, before a mutually acceptable referee or, if the parties cannot agree, a referee selected by the Presiding Judge of San Mateo County, California. Such proceeding shall be conducted in San Mateo County, California, with California
rules of evidence and discovery applicable to such proceeding. 
 (iii) In the event Claims are to be resolved by judicial reference, either
party may seek from a court of competent jurisdiction identified in Section 12(n), any prejudgment order, writ or other relief and have such prejudgment order, writ or other relief enforced to the fullest extent permitted by law notwithstanding
that all Claims are otherwise subject to resolution by judicial reference. 
 (p) Counterparts. This Agreement and any amendments,
waivers, consents or supplements hereto may be executed in any number of counterparts, and by different parties hereto in separate counterparts, each of which when so delivered shall be deemed an original, but all of which counterparts shall
constitute but one and the same instrument. 
 [Remainder of Page Intentionally Left Blank] 

  
 20 








 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed by its officers
thereunto duly authorized as of the Effective Date. 
  

							
	COMPANY:	  	TRICIDA, INC.
				
		  		  	By:	  	
                     
                                         
                           

		  		  	Name:	  	  

		  		  	Title:	  	  

		
	WARRANTHOLDER:	  	HERCULES CAPITAL, INC.
				
		  		  	By:	  	  

		  		  	Name:	  	  

		  		  	Title:	  	  



  
 21 








 EXHIBIT I 

NOTICE OF EXERCISE 
 To: Tricida,
Inc. 
  

	(1)	The undersigned Warrantholder hereby elects to purchase [            ] shares of the Common Stock of Tricida, Inc., pursuant to the terms of the Warrant
Agreement dated [            ] (the “Agreement”) between Tricida, Inc. and the Warrantholder, and [CASH PAYMENT: tenders herewith payment of the Purchase Price in full,
together with all applicable transfer taxes, if any.] [NET ISSUANCE: elects pursuant to Section 3(a) of the Agreement to effect a Net Issuance.] 

  

	(2)	Please issue a certificate or certificates representing said shares of Common Stock in the name of the undersigned or in such other name as is specified below. 


 

							
		 		  	  
 (Name)

			
		 		  	  
 (Address)

		
	WARRANTHOLDER:	 	HERCULES CAPITAL, INC.
				
		 		  	By:	  	
                     
                                         
                   

		 		  	Name:	  	  

		 		  	Title:	  	  

		 		  	Date:	  	  



  
 22 








 EXHIBIT II 

ACKNOWLEDGMENT OF EXERCISE 
 The
undersigned Tricida, Inc., hereby acknowledges receipt of the “Notice of Exercise” from Hercules Capital, Inc., to purchase [            ] shares of the Common Stock of Tricida,
Inc., pursuant to the terms of the Warrant Agreement by and between Tricida, Inc. and Hercules Capital, Inc., dated [            ] (the “Agreement”), and further
acknowledges that [            ] shares of Common Stock remain subject to purchase under the terms of the Agreement. 

 

							
	 COMPANY:
	 	 Tricida, Inc.

				
		 		  	 By:
	  	
              
                                         
                          

		 		  	 Title:
	  	  

		 		  	 Date:
	  	  



  
 23 








 EXHIBIT III 

TRANSFER NOTICE 
 (To transfer or
assign the foregoing Agreement execute this form and supply required information. Do not use this form to purchase shares.) 
 FOR VALUE
RECEIVED, the foregoing Agreement and all rights evidenced thereby are hereby transferred and assigned to 
  

	
	
	  
 (Please Print)

 
 whose address
is                                        
                                         
                                         
                                      



  
  

 

			
		 	Dated:                                     
                                         
                   
		
		 	Holder’s Signature:                                 
                                         
  
		
		 	Holder’s
Address:                                       
                                       
		
		 	  



Signature Guaranteed:                 
                                         
                                         
                                         
                          

NOTE: The signature to this Transfer Notice must correspond with the name as it appears on the face of the Agreement, without alteration
or enlargement or any change whatever. Officers of corporations and those acting in a fiduciary or other representative capacity should file proper evidence of authority to assign the foregoing Agreement. 







 ANNEX C 

EXHIBIT J 
 FORM OF
WARRANT FOR HERCULES TECHNOLOGY III, L.P. 
 THIS WARRANT, AND THE SECURITIES ISSUABLE UPON THE EXERCISE OF THIS WARRANT, HAVE NOT BEEN REGISTERED UNDER
THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR ANY STATE SECURITIES LAWS. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION
OF COUNSEL (WHICH MAY BE COMPANY COUNSEL) REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT, OR ANY APPLICABLE STATE SECURITIES LAWS. 

WARRANT AGREEMENT 
 To Purchase
Shares of Common Stock of 
 Tricida, Inc. 

Dated as of [    ] (the “Effective Date”) 

WHEREAS, Tricida, Inc., a Delaware corporation has entered into a Loan and Security Agreement, dated as of February 28, 2018 (the “Loan
Agreement”), with Hercules Capital, Inc., a Maryland corporation, in its capacity as administrative and collateral agent, Hercules Technology III, L.P., a Delaware limited partnership (the “Warrantholder”) and the other
lender parties thereto; 
 WHEREAS, the Company (as defined below) desires to grant to the Warrantholder, in consideration for, among other things, the
financial accommodations provided for in the Loan Agreement, the right to purchase shares of Common Stock (as defined below) pursuant to this Warrant Agreement (the “Agreement”); 

NOW, THEREFORE, in consideration of the Warrantholder executing and delivering the Loan Agreement and providing the financial accommodations contemplated
therein, and in consideration of the mutual covenants and agreements contained herein, the Company and the Warrantholder agree as follows: 
 SECTION 1.
GRANT OF THE RIGHT TO PURCHASE COMMON STOCK. 
 For value received, the Company hereby grants to the Warrantholder, and the Warrantholder is
entitled, upon the terms and subject to the conditions hereinafter set forth, to subscribe for and purchase, from the Company, an aggregate number of fully paid and non-assessable shares of Common Stock equal
to the quotient derived by dividing (a) the Warrant Coverage (as defined below) by (b) the Exercise Price (as defined below). The Exercise Price of such shares are subject to adjustment as provided in Section 8. As used herein, the
following terms shall have the following meanings: 
 “Act” means the Securities Act of 1933, as amended. 

“Charter” means the Company’s Certificate of Incorporation, as may be amended from time to time. 

“Common Stock” means the Company’s common stock, $0.001 par value per share. 

“Company” means Tricida, Inc., a Delaware corporation. 

  
 25 








 “Exercise Price” means the lesser of (a) if the Company achieves the IPO
Milestone, the initial price to the public per share of Common Stock specified in the final prospectus filed with the SEC with respect to the Company’s Initial Public Offering, or (b) the Series D Conversion Price. In no event shall the
Exercise Price be less than the Floor Price.” 
 “Floor Price” means $.20/share of Common Stock. 

“Initial Public Offering” means the initial underwritten public offering of the Common Stock pursuant to a registration
statement under the Act, which registration statement has been declared effective by the Securities and Exchange Commission (“SEC”). 

“IPO Milestone” means receipt by the Company, prior to December 15, 2018, of at least One Hundred Million Dollars
($100,000,000.00) in aggregate proceeds (net of underwriting discounts and commissions) from an Initial Public Offering. 
 “Merger
Event” means any sale, lease, exclusive license or other transfer of all or substantially all assets of the Company or any merger or consolidation involving the Company in which the Company is not the surviving entity, or in which the
outstanding shares of the Company’s capital stock are otherwise converted into or exchanged for shares of common stock, preferred stock, other securities or property of another entity; other than any such consolidation, merger or reorganization
in which the shares of capital stock of the Company immediately prior to such consolidation, merger or reorganization, continue to represent a majority of the voting power of the surviving entity (or, if the surviving entity is a wholly owned
subsidiary, its parent) immediately after such consolidation, merger or reorganization (provided that, all shares of Common Stock issuable upon exercise of options or warrants outstanding immediately prior to such consolidation or merger or upon
conversion of convertible securities outstanding immediately prior to such merger or consolidation shall be deemed to be outstanding immediately prior to such merger or consolidation and, if applicable, converted or exchanged in such merger or
consolidation on the same terms as the actual outstanding shares of capital stock are converted or exchanged). 
 “Preferred
Stock” means the Company’s Series D preferred stock, $0.001 par value per share, as presently constituted, and, to the extent provided in Section 8(b), any other stock into or for which such Preferred Stock may be converted or
exchanged. 
 “Purchase Price” means, with respect to any exercise of this Agreement, an amount equal to the Exercise Price
as of the relevant time multiplied by the number of shares of Common Stock requested to be exercised under this Agreement pursuant to such exercise. 

“Series D Conversion Price” has the meaning set forth in the Charter. 

“Warrant Coverage” means [Two Hundred Thousand Dollars ($200,000.00)]1 [0.80% of such amount advanced under Tranche 2, Tranche 3, Tranche 4 or Tranche 5 (as defined and set forth in the Loan Agreement), as applicable to the tranche under which the Agreement was entered
into by the parties hereto in connection with the Term Loan Advance (as defined in the Loan Agreement)]2. 

SECTION 2. TERM OF THE AGREEMENT. 
 Except as
otherwise provided for herein, the term of this Agreement and the right to purchase Common Stock as granted herein (the “Warrant”) shall commence on the Effective Date and shall be exercisable for a period ending upon the earliest
to occur of (i) February 28, 2025; (ii) three (3) years after the Initial Public Offering; and (iii) immediately prior to the closing of a Merger Event (the “Exercise Period”). 

 
  

	1 	Note: Only Tranche 1. 


	2 	Note: Warrantholder to complete based off of applicable Tranche. 


  
 26 








 SECTION 3. EXERCISE OF THE PURCHASE RIGHTS. 

(a) Exercise. The purchase rights set forth in this Agreement are exercisable by the Warrantholder, in whole or in part, at any time, or
from time to time, prior to the expiration of the Exercise Period, by tendering to the Company at its principal office a notice of exercise in the form attached hereto as Exhibit I (the “Notice of Exercise”), duly completed
and executed. Promptly upon receipt of the Notice of Exercise and the payment of the Purchase Price in accordance with the terms set forth below, and in no event later than five (5) days thereafter, the Company shall issue to the Warrantholder
a certificate for the number of shares of Common Stock purchased and shall execute the acknowledgment of exercise in the form attached hereto as Exhibit II (the “Acknowledgment of Exercise”) indicating the number of shares
which remain subject to future purchases under this Warrant, if any. 
 The Purchase Price may be paid at the Warrantholder’s election either
(i) by cash or check, or (ii) by surrender of all or a portion of the Warrant for shares of Common Stock to be exercised under this Agreement and, if applicable, an amended Agreement representing the remaining number of shares purchasable
hereunder, as determined below (“Net Issuance”). If the Warrantholder elects the Net Issuance method, the Company will issue shares of Common Stock in accordance with the following formula: 

X = Y(A-B) 

A 
  

							
	        	 	Where:	  	X =	  	the number of shares of Common Stock to be issued to the Warrantholder.
		 		  	Y =	  	the number of shares of Common Stock requested to be purchased under this Agreement.
		 		  	A =	  	the fair market value of one (1) share of Common Stock at the time of issuance of such shares of Common Stock.
		 		  	B =	  	the Exercise Price.

 For purposes of the above calculation, current fair market value of Common Stock shall mean with respect to each share of
Common Stock: 
 (i) if the exercise is in connection with an Initial Public Offering, and if the Company’s Registration Statement
relating to such Initial Public Offering has been declared effective by the SEC, then the fair market value per share shall be the initial “Price to Public” of the Common Stock specified in the final prospectus with respect to the
offering; 
 (ii) if the exercise is after, and not in connection with an Initial Public Offering, and: 

(A) if the Common Stock is traded on a securities exchange, the fair market value shall be deemed to be the average of the
closing prices over a five (5) trading day period ending three (3) days before the day the current fair market value of the securities is being determined; or 

(B) if the Common Stock is traded
over-the-counter, the fair market value shall be deemed to be the average of the closing bid and asked price quoted on the NASDAQ system (or similar system) over the
five (5) trading day period ended three (3) days before the day the current fair market value of the securities is being determined; 

  
 27 








 (iii) if at any time the Common Stock is not listed on any securities exchange or quoted in the
NASDAQ National Market or the over-the-counter market, the current fair market value of Common Stock shall be the highest price per share which the Company could
reasonably expect to obtain from a willing buyer (not a current employee or director) for shares of Common Stock sold by the Company, from authorized but unissued shares, as determined in good faith by its Board of Directors (provided that if the
Company is then in possession of a recent valuation of the Company’s Common Stock, the Board of Directors may rely on such valuation), unless the Notice of Exercise is delivered in connection with a Merger Event, in which case the fair market
value of Common Stock shall be deemed to be the per share value received by the holders of the Company’s Common Stock on a common equivalent basis pursuant to such Merger Event. 

Upon partial exercise by either cash or Net Issuance, the Company shall promptly issue an amended Agreement representing the remaining number of shares
purchasable hereunder. All other terms and conditions of such amended Agreement shall be identical to those contained herein, including, but not limited to the Effective Date hereof and Exercise Period. 

(b) Exercise Prior to Expiration. To the extent this Agreement is not previously exercised as to all shares of Common Stock subject
hereto, and if the fair market value of one share of the Common Stock is greater than the Exercise Price then in effect, this Agreement shall be deemed automatically exercised pursuant to Section 3(a) (even if not surrendered) as of the last
day of the Exercise Period. For purposes of such automatic exercise, the fair market value of one share of the Common Stock upon such expiration shall be determined pursuant to Section 3(a). To the extent this Agreement or any portion thereof
is deemed automatically exercised pursuant to this Section 3(b), the Company agrees to promptly notify the Warrantholder of the number of shares of Common Stock, if any, the Warrantholder is to receive by reason of such automatic exercise. 

SECTION 4. RESERVATION OF SHARES. 
 During the term of
this Agreement, the Company will at all times have authorized and reserved a sufficient number of shares of its Common Stock to provide for the exercise of the rights to purchase Common Stock as provided for herein. 

SECTION 5. NO FRACTIONAL SHARES OR SCRIP. 
 No fractional
shares or scrip representing fractional shares shall be issued upon the exercise of this Agreement, but in lieu of such fractional shares, the Company shall make a cash payment therefor equal to such fraction multiplied by the then fair market value
of one share of Common Stock. 
 SECTION 6. NO RIGHTS AS STOCKHOLDER. 

This Agreement does not entitle the Warrantholder to any voting rights or other rights as a stockholder of the Company prior to the exercise of this Agreement.

 SECTION 7. WARRANTHOLDER REGISTRY. 
 The Company
shall maintain a registry showing the name and address of the registered holder of this Agreement. The Warrantholder’s initial address, for purposes of such registry, is set forth below the Warrantholder’s signature on this Agreement. The
Warrantholder may change such address by giving written notice of such changed address to the Company. 
 SECTION 8. ADJUSTMENT RIGHTS. 

The Exercise Price and the number of shares of Common Stock purchasable hereunder are subject to adjustment, as follows: 

  
 28 








 (a) Merger Event. If at any time there shall be a Merger Event, then, as a part of such
Merger Event, lawful provision shall be made so that the Warrantholder shall be entitled to receive, concurrently with the closing of such Merger Event, the number of shares of Common Stock or other securities or property, if any, (collectively,
“Reference Property”) that the Warrantholder would have received in connection with such Merger Event if Warrantholder had exercised this Agreement immediately prior to the Merger Event pursuant to the Net Issuance provisions of
this Warrant Agreement without actually exercising such right. 
 (b) Reclassification of Shares. Except for Merger Events subject to
Section 8(a), if the Company at any time shall, by combination, reclassification, exchange or subdivision of securities or otherwise, change any of the securities as to which purchase rights under this Agreement exist into the same or a
different number of securities of any other class or classes, this Agreement shall thereafter represent the right to acquire such number and kind of securities as would have been issuable as the result of such change with respect to the securities
which were subject to the purchase rights under this Agreement immediately prior to such combination, reclassification, exchange, subdivision or other change. The provisions of this Section 8(b) shall similarly apply to any successive
combination, reclassification, exchange, subdivision or other change. 
 (c) Subdivision or Combination of Shares. If the Company at
any time shall combine or subdivide its Common Stock, (i) in the case of a subdivision, the Exercise Price shall be proportionately decreased and the number of shares of Common Stock issuable hereunder shall be proportionately increased, or
(ii) in the case of a combination, the Exercise Price shall be proportionately increased and the number of shares of Common Stock issuable hereunder shall be proportionately decreased. 

(d) Dividends. If the Company at any time prior to the Initial Public Offering and while this Agreement is outstanding and unexpired
shall: 
 (i) pay a dividend with respect to the Common Stock payable in Common Stock, then the Exercise Price shall be adjusted, from and
after the date of determination of the stockholders entitled to receive such dividend or distribution, to that price determined by multiplying the Exercise Price in effect immediately prior to such date of determination by a fraction (A) the
numerator of which shall be the total number of shares of Common Stock outstanding immediately prior to such dividend or distribution, and (B) the denominator of which shall be the total number of shares of Common Stock outstanding immediately
after such dividend or distribution; or 
 (ii) make any other dividend or distribution with respect to Common Stock, except any dividend or
distribution specifically provided for in any other clause of this Section 8, then, in each such case, provision shall be made by the Company such that the Warrantholder shall receive upon exercise or conversion of this Warrant a proportionate
share of any such dividend or distribution as though it were the holder of the Common Stock as of the record date fixed for the determination of the stockholders of the Company entitled to receive such dividend or distribution. 

(e) [Intentionally omitted]. 

(f) Notice of Adjustments. If prior to Initial Public Offering: (i) the Company shall declare any dividend or distribution upon its
stock, whether in stock, cash, property or other securities; (ii) there shall be any Merger Event; or (iii) there shall be any voluntary dissolution, liquidation or winding up of the Company; then, in connection with each such event, the
Company shall send to the Warrantholder: (A) at least fifteen (15) days’ prior written notice of the date on which the books of the Company shall close or a record shall be taken for such dividend, distribution, subscription rights
(specifying the date on which the holders of Common Stock shall be entitled thereto) or for determining rights to vote in respect of such Merger Event, dissolution, liquidation or winding up; and (B) in the case of any such Merger Event,
dissolution, liquidation or winding up, at least fifteen (15) days’ prior written notice of the date when the same shall take place (and specifying the date on which the holders of Common Stock shall be entitled to exchange their Common
Stock for securities or other property deliverable upon such Merger Event, dissolution, liquidation or winding up). 

  
 29 








 Each such written notice shall be given in accordance with Section 12(g) below and shall set forth, in
reasonable detail, (i) the event requiring the notice, and (ii) if any adjustment is required to be made pursuant to this Section 8, (A) the amount of such adjustment, (B) the method by which such adjustment was calculated,
(C) the adjusted Exercise Price (if the Exercise Price has been adjusted), and (D) the number of shares subject to purchase hereunder after giving effect to such adjustment. 

(g) Timely Notice. Notwithstanding the failure to timely provide any such notice required by Section 8(f) above, the Warrantholder
shall retain the benefit of the applicable notice period notwithstanding anything to the contrary contained in any insufficient notice received by the Warrantholder. 

SECTION 9. REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE COMPANY. 

(a) Reservation of Common Stock. The Common Stock issuable upon exercise of this Agreement has been duly and validly reserved and, when
issued in accordance with the provisions of this Agreement, will be validly issued, fully paid and non-assessable, and will be free of any taxes, liens, charges or encumbrances created by the Company;
provided, that the Common Stock issuable pursuant to this Agreement may be subject to restrictions on transfer under state and/or federal securities laws. The Company has made available to the Warrantholder true, correct and complete copies
of its Charter and current bylaws as of the Effective Date. The issuance of certificates for shares of Common Stock upon exercise of this Agreement shall be made without charge to the Warrantholder for any issuance tax in respect thereof, or other
cost incurred by the Company in connection with such exercise and the related issuance of shares of Common Stock; provided, that the Company shall not be required to pay any tax which may be payable in respect of any transfer and the issuance
and delivery of any certificate in a name other than that of the Warrantholder. 
 (b) Due Authority. The execution and delivery by
the Company of this Agreement and the performance of all obligations of the Company hereunder, including the issuance to the Warrantholder of the right to acquire the shares of Common Stock, have been duly authorized by all necessary corporate
action on the part of the Company. This Agreement: (i) does not violate the Charter or the Company’s current bylaws; (ii) does not contravene any law or governmental rule, regulation or order applicable to the Company; and
(iii) does not contravene any provision of, or constitute a default under, any indenture, mortgage, contract or other instrument to which the Company is a party or by which it is bound. This Agreement constitutes a legal, valid and binding
agreement of the Company, enforceable in accordance with its terms, except (i) as limited by applicable bankruptcy, insolvency, reorganization, moratorium or other laws of general application affecting enforcement of creditors’ rights and
(b) as limited by general principles of equity that restrict the availability of equitable remedies. 
 (c) Consents and
Approvals. No consent or approval of, giving of notice to, registration with, or taking of any other action in respect of any state, federal or other governmental authority or agency is required with respect to the execution, delivery and
performance by the Company of its obligations under this Agreement, except for the filing of notices pursuant to Regulation D under the Act and any filing required by applicable state securities law, which filings will be effective by the time
required thereby. 
 (d) Issued Securities.3 All issued and outstanding shares of
Common Stock, preferred stock or any other securities of the Company have been duly authorized and validly issued and are fully paid and nonassessable. All outstanding shares of Common Stock, preferred stock and any other securities were issued in
full compliance with all federal and state securities laws. In addition, as of the date immediately preceding the date of this Agreement: 

(i) The authorized capital of the Company consists of (A) [134,000,000] shares of Common Stock, of which [9,152,544] shares are
issued and outstanding; (B) [11,398,694] shares of Series A preferred stock, $0.001 par value per share, of which [11,302,758] shares are issued and outstanding and are convertible into an aggregate of [11,302,758] shares of Common Stock at [$0.886]
per share; (C) [32,526,878] shares of 
  
  

	3 	 Note: To be updated with each warrant issuance.




  
 30 








 
Series B preferred stock, $0.001 par value per share, of which [32,526,878] shares are issued and outstanding and are convertible into an aggregate of [32,526,878] shares of Common Stock at
[$0.93] per share; (D) [35,806,451] shares of Series C preferred stock, $0.001 par value per share, of which [35,806,451] shares are issued and outstanding and are convertible into an aggregate of [35,806,451] shares of Common Stock at [$1.55] per
share; and (E) [24,500,000] shares of Series D preferred stock, $0.001 par value per share, of which [24,493,615] shares are issued and outstanding and are convertible into an aggregate of [24,493,615] shares of Common Stock at [$2.35] per share.

 (ii) The Company issued a warrant dated August 9, 2013 exercisable for 95,936 shares of Series A preferred stock.

 (iii) The Company has reserved [18,040,000] shares of Common Stock for issuance under its stock option plan(s), under
which options to purchase [14,115,728] shares of Common Stock are outstanding. Except as noted in clause (i) above, there are no other options, warrants, or other rights presently outstanding to purchase or otherwise acquire any authorized but
unissued shares of the Company’s capital stock of the Company. 
 (iv) No stockholder of the Company has preemptive
rights to purchase new issuances of the Company’s capital stock, other than pursuant to the Investor Rights Agreement (as defined below) and the Loan Agreement. 

(e) Registration Rights. The Company agrees that the shares of Common Stock issued upon exercise of this Warrant shall have the
“Piggyback” and S-3 registration rights pursuant to and as set forth in the Company’s Amended and Restated Investor Rights Agreement, dated November 7, 2017, as amended from time to time
(the “Investor Rights Agreement”) on a pari passu basis with the holders of outstanding shares of Preferred Stock who are parties thereto. The provisions set forth in the Company’s Investor Rights Agreement or similar
agreement relating to such registration rights in effect as of the Effective Date may not be amended, modified or waived without the prior written consent of the Warrantholder unless such amendment, modification or waiver affects the rights
associated with the shares of Common Stock issued and issuable upon exercise hereof in the same manner as such amendment, modification or waiver affects the rights associated with the shares of Common Stock issuable upon conversion of all
outstanding shares of Preferred Stock whose holders are parties thereto. 
 (f) Other Commitments to Register Securities. Except as
set forth in this Agreement or the Investor Rights Agreement, the Company is not, pursuant to the terms of any other agreement currently in existence, under any obligation to register under the Act any of its presently outstanding securities or any
of its securities which may hereafter be issued. 
 (g) Exempt Transaction. Subject to the accuracy of the Warrantholder’s
representations in Section 10, the issuance of the Common Stock upon exercise of this Agreement will constitute a transaction exempt from (i) the registration requirements of Section 5 of the Act, in reliance upon Section 4(2)
thereof, and (ii) the qualification requirements of the applicable state securities laws. 
 (h) Compliance with Rule 144. If the
Warrantholder proposes to sell Common Stock issuable upon the exercise of this Agreement in compliance with Rule 144 promulgated by the SEC, then, upon the Warrantholder’s written request to the Company, the Company shall furnish to the
Warrantholder, within ten days after receipt of such request, a written statement confirming the status of the Company’s compliance with the filing requirements of the SEC as set forth in such Rule, as such Rule may be amended from time to
time. 
 (i) Information Rights. During the term of this Warrant, and only if the Initial Public Offering has not occurred, the
Warrantholder will receive the Company’s audited financial statements in the manner and within the time period provided for with respect to the Major Investors (as defined in the Investor Rights Agreement) pursuant to Section 3.1(b) of the
Investor Rights Agreement; provided, however, that any waiver of such information rights by the Major Investors pursuant to the Investor Rights Agreement shall not act as a waiver of the Warrantholder’s information rights provided
for under this Section 9(i). 

  
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 SECTION 10. REPRESENTATIONS AND COVENANTS OF THE WARRANTHOLDER. 

This Agreement has been entered into by the Company in reliance upon the following representations and covenants of the Warrantholder: 

(a) Investment Purpose. The right to acquire Common Stock is being acquired for investment and not with a view to the sale or
distribution of any part thereof, and the Warrantholder has no present intention of selling or engaging in any public distribution of such rights or the Common Stock except pursuant to an effective registration statement or an exemption from the
registration requirements of the Act. 
 (b) Private Issue. The Warrantholder understands (i) that the Common Stock issuable upon
exercise of this Agreement is not registered under the Act or qualified under applicable state securities laws on the ground that the issuance contemplated by this Agreement will be exempt from the registration and qualifications requirements
thereof, and (ii) that the Company’s reliance on such exemption is predicated on the representations set forth in this Section 10. 

(c) Financial Risk. The Warrantholder has such knowledge and experience in financial and business matters as to be capable of evaluating
the merits and risks of its investment, and has the ability to bear the economic risks of its investment. 
 (d) Risk of No
Registration. The Warrantholder understands that if the Company does not register with the SEC pursuant to Section 12 of the Securities Exchange Act of 1934 (the “1934 Act”), or file reports pursuant to Section 15(d)
of the 1934 Act, or if a registration statement covering the securities under the Act is not in effect when it desires to sell (i) the rights to purchase Common Stock pursuant to this Agreement or (ii) the Common Stock issuable upon
exercise of the right to purchase, it may be required to hold such securities for an indefinite period. The Warrantholder also understands that any sale of (A) its rights hereunder to purchase Common Stock or (B) Common Stock issued or
issuable hereunder which might be made by it in reliance upon Rule 144 under the Act may be made only in accordance with the terms and conditions of that Rule. 

(e) Accredited Investor. The Warrantholder is an “accredited investor” within the meaning of the Securities and Exchange Rule
501 of Regulation D, as presently in effect. 
 (f) For purposes of the rights contemplated by Section 9(e) of this Agreement, upon
exercise of the Warrant, the Warrantholder hereby agrees to be bound by and subject to the terms and provisions of the Investor Rights Agreement as if the Warrantholder was an “Investor” (as defined in the Investor Rights Agreement) party
thereto. 
 (g) Upon exercise of the Warrant, the Warrantholder hereby agrees to be bound by and subject to the terms and provisions of
Section 1.8, Section 2 and Section 3 of the Company’s Amended and Restated Voting Agreement, dated November 7, 2017, as amended from time to time (the “Voting Agreement”), as if the Warrantholder were a
“Stockholder” (as defined in the Voting Agreement) party thereto. 
 SECTION 11. TRANSFERS. 

Subject to compliance with applicable federal and state securities laws, this Agreement and all rights hereunder are transferable, in whole or in part, without
charge to the holder hereof (except for transfer taxes) upon surrender of this Agreement properly endorsed; provided, however, that if there is not then any ongoing Event of Default (as defined in the Loan Agreement), then such
transfer shall be subject to the prior written consent of the Company; provided further, that notwithstanding the foregoing, any such transfer to an Affiliate (as defined in the Loan Agreement) of the Warrantholder shall be allowed at any
time without the 

  
 32 








 
prior written consent of the Company. Each taker and holder of this Agreement, by taking or holding the same, consents and agrees that this Agreement, when endorsed in blank, shall be deemed
negotiable, and that the holder hereof, when this Agreement shall have been so endorsed and its transfer recorded on the Company’s books, shall be treated by the Company and all other persons dealing with this Agreement as the absolute owner
hereof for any purpose and as the person entitled to exercise the rights represented by this Agreement. The transfer of this Agreement shall be recorded on the books of the Company upon receipt by the Company of a notice of transfer in the form
attached hereto as Exhibit III (the “Transfer Notice”), at its principal offices and the payment to the Company of all transfer taxes and other governmental charges imposed on such transfer. Until the Company receives such Transfer
Notice, the Company may treat the registered owner hereof as the owner for all purposes. The Warrantholder may not transfer this Warrant to a competitor of the Company, as reasonably determined by the Board of Directors. 

SECTION 12. MISCELLANEOUS. 
 (a)
Effective Date. The provisions of this Agreement shall be construed and shall be given effect in all respects as if it had been executed and delivered by the Company on the date hereof. This Agreement shall be binding upon any successors or
assigns of the Company. 
 (b) Remedies. In the event of any default hereunder, the
non-defaulting party may proceed to protect and enforce its rights either by suit in equity and/or by action at law, including but not limited to an action for damages as a result of any such default, and/or
an action for specific performance for any default where the Warrantholder will not have an adequate remedy at law and where damages will not be readily ascertainable. The Company expressly agrees that it shall not oppose an application by the
Warrantholder or any other person entitled to the benefit of this Agreement requiring specific performance of any or all provisions hereof or enjoining the Company from continuing to commit any such breach of this Agreement. 

(c) No Impairment of Rights. The Company will not, by amendment of its Charter or through any other means, avoid or seek to avoid the
observance or performance of any of the terms of this Agreement, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions as may be necessary or appropriate in order to protect the rights
of the Warrantholder against impairment. 
 (d) Additional Documents. The Company, upon execution of this Agreement, shall provide the
Warrantholder with a certified copy of resolutions of the Company’s board of directors evidencing approval of this Agreement and the reservation of the shares of Common Stock issuable upon exercise of the Warrant. Prior to the Initial Public
Offering, the Company shall also supply documentation reasonably requested by the Warrantholder to evaluate whether to exercise this Warrant, including without limitation, (i) any merger/purchase/asset sale agreement and related documents and
estimated payout allocations to each of the respective stockholders, warrant and option holders in connection with a Merger Event, (ii) the most recent capitalization tables, 409A valuations (if any), and board determination of share value
(including any waterfall or per share allocations provided to the stockholders), and (iii) most recent Charter. 
 (e)
Attorney’s Fees. In any litigation, arbitration or court proceeding between the Company and the Warrantholder relating hereto, the prevailing party shall be entitled to attorneys’ fees and expenses and all costs of proceedings
incurred in enforcing this Agreement. For the purposes of this Section 12(e), attorneys’ fees shall include without limitation fees incurred in connection with the following: (i) contempt proceedings; (ii) discovery; (iii) any
motion, proceeding or other activity of any kind in connection with an insolvency proceeding; (iv) garnishment, levy, and debtor and third party examinations; and (v) post-judgment motions and proceedings of any kind, including without
limitation any activity taken to collect or enforce any judgment. 
 (f) Severability. In the event any one or more of the provisions
of this Agreement shall for any reason be held invalid, illegal or unenforceable, the remaining provisions of this Agreement shall be unimpaired, and the invalid, illegal or unenforceable provision shall be replaced by a mutually acceptable valid,
legal and enforceable provision, which comes closest to the intention of the parties underlying the invalid, illegal or unenforceable provision. 

  
 33 








 (g) Notices. Except as otherwise provided herein, any notice, demand, request, consent,
approval, declaration, service of process or other communication that is required, contemplated, or permitted under this Agreement or with respect to the subject matter hereof shall be in writing, and shall be deemed to have been validly served,
given, delivered, and received upon the earlier of: (i) the day of transmission by electronic mail or hand delivery if transmission or delivery occurs on a business day at or before 5:00 pm in the time zone of the recipient, or, if transmission
or delivery occurs on a non-business day or after such time, the first business day thereafter, or the first business day after deposit with an overnight express service or overnight mail delivery service; or
(ii) the third (3rd) calendar day after deposit in the United States mails, with proper first class postage prepaid, and shall be addressed to the party to be notified as follows: 

If to the Warrantholder: 

HERCULES TECHNOLOGY III, L.P. 

Legal Department 

Attention: Chief Legal Officer and Himani Bhalla 

400 Hamilton Avenue, Suite 310 

Palo Alto, CA 94301 

Telephone: 650-289-3060 

with a copy to (which shall not constitute notice): 

LATHAM & WATKINS LLP 

Attention: Haim Zaltzman 

140 Scott Drive 

Menlo Park, CA 94025 

Telephone: 650-328-4600 

If to the Company: 
 TRICIDA,
INC. 
 Attention: Legal Department 

7000 Shoreline Court, Suite 201 

South San Francisco, CA 94080 

Telephone: (415) 988-2420 

with a copy to (which shall not constitute notice): 

SIDLEY AUSTIN LLP 

Attention: Geoffrey W. Levin 

787 Seventh Avenue 

New York, NY 10019 

Telephone: 212-839-5776 

or to such other address as each party may designate for itself by like notice. 

  
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 (h) Entire Agreement; Amendments. This Agreement constitutes the entire agreement and
understanding of the parties hereto in respect of the subject matter hereof, and supersedes and replaces in their entirety any prior proposals, term sheets, letters, negotiations or other documents or agreements, whether written or oral, with
respect to the subject matter hereof (including the Warrantholder’s proposal letter dated January 19, 2018). None of the terms of this Agreement may be amended except by an instrument executed by each of the parties hereto. 

(i) Headings. The various headings in this Agreement are inserted for convenience only and shall not affect the meaning or
interpretation of this Agreement or any provisions hereof. 
 (j) No Strict Construction. The parties hereto have participated jointly
in the negotiation and drafting of this Agreement. In the event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties hereto and no presumption or burden of proof shall
arise favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement. 
 (k) No Waiver. No omission
or delay by the Warrantholder at any time to enforce any right or remedy reserved to it, or to require performance of any of the terms, covenants or provisions hereof by the Company at any time designated, shall be a waiver of any such right or
remedy to which the Warrantholder is entitled, nor shall it in any way affect the right of the Warrantholder to enforce such provisions thereafter. 

(l) Survival. All agreements, representations and warranties contained in this Agreement or in any document delivered pursuant hereto
shall be for the benefit of the Warrantholder or Company, as applicable, and shall survive the execution and delivery of this Agreement and the expiration or other termination of this Agreement. 

(m) Governing Law. This Agreement has been negotiated and delivered to Warrantholder in the State of California, and shall have been
accepted by the Warrantholder in the State of California. Delivery of Common Stock to the Warrantholder by the Company under this Agreement is due in the State of California. This Agreement shall be governed by, and construed and enforced in
accordance with, the laws of the State of California, excluding conflict of laws principles that would cause the application of laws of any other jurisdiction. 

(n) Consent to Jurisdiction and Venue. All judicial proceedings arising in or under or related to this Agreement may be brought in any
state or federal court of competent jurisdiction located in the State of California. By execution and delivery of this Agreement, each party hereto generally and unconditionally: (a) consents to nonexclusive personal jurisdiction in San Mateo
County, State of California; (b) waives any objection as to jurisdiction or venue in San Mateo County, State of California; (c) agrees not to assert any defense based on lack of jurisdiction or venue in the aforesaid courts; and
(d) irrevocably agrees to be bound by any judgment rendered thereby in connection with this Agreement or the other Loan Documents. Service of process on any party hereto in any action arising out of or relating to this Agreement shall be
effective if given in accordance with the requirements for notice set forth in Section 12(g), and shall be deemed effective and received as set forth in Section 12(g). Nothing herein shall affect the right to serve process in any other
manner permitted by law or shall limit the right of either party to bring proceedings in the courts of any other jurisdiction. 
 (o)
Mutual Waiver of Jury Trial/ Judicial Reference. 
 (i) Because disputes arising in connection with complex financial transactions
are most quickly and economically resolved by an experienced and expert Person and the parties wish applicable state and federal laws to apply (rather than arbitration rules), the parties desire that their disputes be resolved by a judge applying
such applicable laws. EACH OF THE COMPANY AND THE WARRANTHOLDER SPECIFICALLY WAIVES ANY RIGHT IT MAY HAVE TO TRIAL BY JURY OF ANY CAUSE OF ACTION, CLAIM, CROSS-CLAIM, COUNTERCLAIM, THIRD PARTY CLAIM OR ANY OTHER CLAIM (COLLECTIVELY,
“CLAIMS”) ASSERTED BY THE COMPANY AGAINST THE WARRANTHOLDER OR ITS ASSIGNEE OR BY THE WARRANTHOLDER OR ITS ASSIGNEE AGAINST THE COMPANY. This waiver extends to all such Claims, including Claims that involve Persons 

  
 35 








 
other than Company and Warrantholder; Claims that arise out of or are in any way connected to the relationship between the Company and the Warrantholder; and any Claims for damages, breach of
contract, tort, specific performance, or any equitable or legal relief of any kind, arising out of this Agreement. 
 (ii) If the waiver of
jury trial set forth in Section 12(o)(i) above is ineffective or unenforceable, the parties agree that all Claims shall be resolved by reference to a private judge sitting without a jury, pursuant to California Code of Civil Procedure
Section 638, before a mutually acceptable referee or, if the parties cannot agree, a referee selected by the Presiding Judge of San Mateo County, California. Such proceeding shall be conducted in San Mateo County, California, with California
rules of evidence and discovery applicable to such proceeding. 
 (iii) In the event Claims are to be resolved by judicial reference, either
party may seek from a court of competent jurisdiction identified in Section 12(n), any prejudgment order, writ or other relief and have such prejudgment order, writ or other relief enforced to the fullest extent permitted by law notwithstanding
that all Claims are otherwise subject to resolution by judicial reference. 
 (p) Counterparts. This Agreement and any amendments,
waivers, consents or supplements hereto may be executed in any number of counterparts, and by different parties hereto in separate counterparts, each of which when so delivered shall be deemed an original, but all of which counterparts shall
constitute but one and the same instrument. 
 [Remainder of Page Intentionally Left Blank] 

  
 36 








 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed by its officers
thereunto duly authorized as of the Effective Date. 
  

							
	COMPANY:	 	TRICIDA, INC.
				
		 		  	By:	  	
                     
                                         
                       

		 		  	Name:	  	  

		 		  	Title:	  	  

		
	WARRANTHOLDER:	 	HERCULES TECHNOLOGY III, L.P.,
		 	a Delaware limited partnership
		
		 	 By: Hercules Technology SBIC Management, LLC,

its General Partner

		
		 	 By: Hercules Capital, Inc.,
 its
Manager

				
		 		  	By:	  	  

		 		  	Name:	  	  

		 		  	Title:	  	  



  
 37 








 EXHIBIT I 

NOTICE OF EXERCISE 
 To: Tricida,
Inc. 
  

	(1)	The undersigned Warrantholder hereby elects to purchase [            ] shares of the Common Stock of Tricida, Inc., pursuant to the terms of the Warrant
Agreement dated [            ] (the “Agreement”) between Tricida, Inc. and the Warrantholder, and [CASH PAYMENT: tenders herewith payment of the Purchase Price in full,
together with all applicable transfer taxes, if any.] [NET ISSUANCE: elects pursuant to Section 3(a) of the Agreement to effect a Net Issuance.] 

  

	(2)	Please issue a certificate or certificates representing said shares of Common Stock in the name of the undersigned or in such other name as is specified below. 


 

					
		 	  
 (Name)

		
		 	  
 (Address)

		
	WARRANTHOLDER:	 	 HERCULES TECHNOLOGY III, L.P.,
 a
Delaware limited partnership

		
		 	 By: Hercules Technology SBIC Management, LLC,

its General Partner

		
		 	By: Hercules Capital, Inc., its Manager
			
		 	By:	  	
                     
                                         
                           

		 	Name:	  	  

		 	Title:	  	  

		 	Date:	  	  



  
 38 








 EXHIBIT II 

ACKNOWLEDGMENT OF EXERCISE 
 The
undersigned Tricida, Inc., hereby acknowledge receipt of the “Notice of Exercise” from Hercules Technology III, L.P., to purchase [            ] shares of the Common Stock of
Tricida, Inc., pursuant to the terms of the Warrant Agreement by and between Tricida, Inc. and Hercules Technology III, L.P., dated [            ] (the “Agreement”), and
further acknowledges that [            ] shares of Common Stock remain subject to purchase under the terms of the Agreement. 

 

							
	COMPANY:	 	Tricida, Inc.
				
		 		  	By:	  	
                     
                                         
                       

		 		  	Title:	  	  

		 		  	Date:	  	  



  
 39 








 EXHIBIT III 

TRANSFER NOTICE 
 (To transfer or
assign the foregoing Agreement execute this form and supply required information. Do not use this form to purchase shares.) 
 FOR VALUE
RECEIVED, the foregoing Agreement and all rights evidenced thereby are hereby transferred and assigned to 

____________________________________________________________________________________________ 

	
	 (Please Print)
  

whose address
is                                        
                                         
                                         
                                      

 




____________________________________________________________________________ 

 

			
		 	Dated:                                     
                                         
                                         
 
		
		 	Holder’s
Signature:                                       
                                         
                   
		
		 	Holder’s
Address:                                       
                                         
                      
		
		 	  



Signature Guaranteed:                 
                                         
                                         
                                         
                            

NOTE: The signature to this Transfer Notice must correspond with the name as it appears on the face of the Agreement, without alteration
or enlargement or any change whatever. Officers of corporations and those acting in a fiduciary or other representative capacity should file proper evidence of authority to assign the foregoing Agreement.