33550 Federal Register / Vol. 66, No. 121 / Friday, June 22, 2001 / Notices

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health

National Institute of Mental Health;

Notice of Closed Meeting

Pursuant to section 10(d) of the

Federal Advisory Committee Act, as

amended (5 U.S.C. Appendix 2), notice

is hereby given of the following

meeting.

The meeting will be closed to the

public in accordance with the

provisions set forth in sections

552b(c)(4) and 552b(c)(6), Title 5 U.S.C.,

as amended. The contract proposals and

the discussions could disclose

confidential trade secrets or commercial

property such as patentable material,

and personal information concerning

individuals associated with the contract

proposals, the disclosure of which

would constitute a clearly unwarranted

invasion of personal privacy.

Name of Committee: National Institute of

Mental Health Special Emphasis Panel.

Date: July 10, 2001.

Time: 9 a.m. to 12 p.m.

Agenda: To review and evaluate contract

proposals.

Place: Marriott Suites Bethesda, 6711

Democracy Boulevard, Bethesda, MD 20817.

Contact Person: Peter J. Sheridan,

Scientific Review Administrator, Division of

Extramural Activities, National Institute of

mental Health, NIH, Neuroscience Center,

6001 Executive Blvd., Room 6142, MSC 9606,

Bethesda, MD 20892–9606, 301–443–1513,

psherida@mail.nih.gov

(Catalogue of Federal Domestic Assistance

Program Nos. 93.242, Mental Health Research

Grants; 93.281, Scientist Development

Award, Scientist Development Award for

Clinicians, and Research Scientist Award;

93.282, Mental Health National Research

Service Awards for Research Training,

National Institutes of Health, HHS)

Dated: June 18, 2001.

LaVerne Y. Stringfield,

Director, Office of Federal Advisory

Committee Policy.

[FR Doc. 01–15769 Filed 6–21–01; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health

Center for Scientific Review; Notice of

Closed Meeting

Pursuant to section 10(d) of the

Federal Advisory Committee Act, as

amended (5 U.S.C. Appendix 2), notice

is hereby given of the following

meeting.

The meeting will be closed to the

public in accordance with the

provisions set forth in sections

552(b)(c)(4) and 552b(c)(6), Title 5

U.S.C., as amended. The grant

applications and the discussions could

disclose confidential trade secrets or

commercial property such as patentable

material, and personal information

concerning individuals associated with

the grant applications, the disclosure of

which would constitute a clearly

unwarranted invasion of personal

privacy.

Name of Committee: Center for Scientific

Review Special Emphasis Panel.

Date: June 20, 2001.

Time: 2:30 p.m. to 3:30 p.m.

Agenda: To review and evaluate grant

applications.

Place: NIH, Rockledge 2, Bethesda, MD

20892 (Telephone Conference Call).

Contact Person: Julian L. Azorlosa,

Scientific Review Administrator, Center for

Scientific Review, National Institutes of

Health, 6701 Rockledge Drive, Room 3190,

MSC 7848, Bethesda, MD 20892, (301) 435–

1507.

This notice is being published less than 15

days prior to the meeting due to the timing

limitations imposed by the review and

funding cycle.

(Catalogue of Federal Domestic Assistance

Program Nos. 93.306, Comparative Medicine,

93.306; 93.333, Clinical Research, 93.333,

93.337, 93.393–93.396, 93.837–93.844,

93.846–93.878, 93.892, 93.893, National

Institutes of Health, HHS)

Dated: June 18, 2001.

LaVerne Y. Stringfield,

Director, Office of Federal Advisory

Committee Policy.

[FR Doc. 01–15765 Filed 6–21–01; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health

Center for Scientific Review; Amended

Notice of Meeting

Notice is hereby given of a change in

the meeting of the Center for Scientific

Review Special Emphasis Panel, June

21, 2001, 8:30 a.m. to June 22, 2001, 6

p.m., River Inn, 924 25th Street, NW.,

Washington, DC, 20037 which was

published in the Federal Register on

June 12, 2001, 66 FR 31683–31685.

The meeting will be one day only

June 21, 2001. The time and location

remain the same. The meeting is closed

to the public.

Dated: June 18, 2001.

LaVerne Y. Stringfield,

Director, Office of Federal Advisory

Committee Policy.

[FR Doc. 01–15768 Filed 6–21–01; 8:45 am]

BILLING CODE 4140–01–M

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

Public Health Service

National Institute of Environmental

Health Sciences (NIEHS); National

Toxicology Program (NTP); The

Revised Draft Up-and-Down Procedure

for Assessing Acute Oral Toxicity:

Notice of Availability and Request for

Public Comments

Summary

Notice is hereby given of the

availability of a revised draft Up-andDown Procedure for assessing acute oral

toxicity and solicitation of public

comment. Documents available include:

(1) A revised draft Up-and-Down

Procedure (UDP) test guideline

(hereafter, revised draft UDP); (2) A

procedure incorporated into the revised

draft UDP for calculating the confidence

interval for the estimated median lethal

dose (LD50); and (3) A software program

for use in establishing test doses,

determining when to stop the test, and

estimating the LD50 and the confidence

interval for the estimated LD50.

Availability of Revised Draft UDP

Documents

The revised draft UDP was proposed

by the U.S. Environmental Protection

Agency (U.S. EPA) to the Interagency

Coordinating Committee on the

Validation of Alternative Methods

(ICCVAM) as an alternate for the

existing conventional LD50 test (EPA

870.1100) used to evaluate the acute

oral toxicity of chemicals. A previous

version of the draft UDP was reviewed

by the UDP Peer Review Panel

(hereafter, Panel) at a meeting on July

25, 2000 organized by the NTP

Interagency Center for the Evaluation of

Alternative Toxicological Methods

(NICEATM) and ICCVAM. This revised

draft UDP incorporates modifications

made in response to the conclusions

and recommendations of the Panel and

may be obtained electronically from the

NICEATM/ICCVAM web site at

http:/iccvam.niehs.nih.gov/methods/

updocs/udprpt/udp_ciprop.htm. For a

paper copy (a limited number are

available), contact NICEATM at (919)

541–3398, or via e-mail at

niceatm@niehs.nih.gov.

The proposed procedure for

calculating the confidence interval for

the estimated LD50 is a statistical

calculation and does not require the use

of test animals beyond what is needed

to estimate the LD50. This procedure

helps to place the estimated LD50 in a

statistical context for hazard and risk

assessment purposes. The confidence