[Federal Register Volume 66, Number 125 (Thursday, June 28, 2001)]
[Notices]
[Pages 34454-34455]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 01-16245]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention


Government-Owned Inventions; Availability for Licensing

AGENCY: Centers for Disease Control and Prevention, Technology Transfer 
Office, Department of Health and Human Services

ACTION: Notice.

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    The inventions named in this notice are owned by agencies of the 
United States Government and are available for licensing in the United 
States (U.S.) in accordance with 35 U.S.C. 207, to achieve expeditious 
commercialization of results of federally funded research and 
development. Foreign patent applications are filed on selected 
inventions to extend market coverage for U.S. companies and may also be 
available for licensing.

ADDRESSES: Licensing information, and copies of the U.S. patent 
applications listed below, may be obtained by writing to Thomas E. 
O'Toole, M.P.H., Deputy Director, Technology Transfer Office, Centers 
for Disease Control and Prevention (CDC), Mailstop E-67, 1600 Clifton 
Rd., Atlanta, GA 30333, telephone (404) 498-0170, facsimile (404) 498-
0095, and e-mail <a href="/cdn-cgi/l/email-protection#fc888893bc9f989fd29b938a"><span class="__cf_email__" data-cfemail="e7939388a7848384c9808891">[email protected]</span></a>. Please note that a signed Confidential 
Disclosure Agreement will be required to receive copies of unpublished 
patent applications.

Apparatus for Applying Chemicals to Rodents

    This invention comprises a method of controlling Lyme disease by 
preventing the maturation of deer ticks on white-footed mice by 
exposing the mice to insecticides as they enter food-baited boxes. 
Other tick- and flea-borne diseases can also be controlled by this 
method.
    Inventors: Gary O. Maupin et al. U.S. Patent Application SN: 09/
595,034 (CDC Ref. #: I-031-00).

Control of Arthropod Vectors of Parasitic Diseases

    This invention comprises a method of controlling Lyme disease by 
preventing the maturation of deer ticks on white-footed mice by 
exposing the mice to insecticides as they enter food-baited boxes. 
Other tick- and flea-borne diseases can also be controlled by this 
method.
    Inventors: Gary O. Maupin et al. U.S. Patent Application SN: 09/
595,035 (CDC Ref. #: I-032-00).

Control of Arthropods in Rodents

    This invention comprises a method of controlling Lyme disease by 
preventing the maturation of deer ticks on white-footed mice by 
exposing the mice to insecticides as they enter food-baited boxes. 
Other tick- and flea-borne diseases can also be controlled by this 
method.
    Inventors: Gary O. Maupin et al. U.S. Patent Application SN: 09/
595,177 (CDC Ref. #: I-041-00).

Method for Monitoring Local Reaction Associated With Injections

    A simple and inexpensive method to give patients a guideline for 
determining the severity of an adverse reaction that may occur at the 
site of injection. Patients can be instructed to notify health care 
providers if an inflammatory response spreads beyond a measured 
distance from the location of injection.
    Inventor: Laurie Kamimoto, U.S. Patent Application SN: 60/238,691 
(CDC Ref. #: I-036-00).

Auscultory Training System

    This invention provides for the precise reproduction of recorded 
sounds. Under ordinary conditions, a sound signal is distorted by the 
amplifier, speakers, and the surroundings. This invention modifies the 
signal delivered to the speaker in such a way as to precisely reproduce 
the signal as it was originally recorded. The graphical user-interface 
allows for the easy selection and playback of individual components of 
a larger sound recording. This invention could have applications as a 
diagnostic screening tool, as a telemedicine tool, and as a teaching 
tool to instruct the user on the various body sounds, such as lung, 
bowel, or heart sounds.
    Inventors: Walter McKinney et al. U.S. Patent Application SN: To be 
assigned, filed 4.30.2001. (CDC Ref. #: I-037-00).

Peptide Vaccines Against Group A Streptococci

    The invention is a vaccine comprised of three synthetic peptides of 
20-25 amino acids in length from different M proteins. The synthetic 
peptides can be recognized by M type-specific antibodies and are 
capable of eliciting functional opsonic antibodies in mice. The vaccine 
may have the potential to eliminate over 85% of Group A Streptococci 
infections and reduce by 85% the nasopharyngeal reservoir of Group A 
Streptococci in the United States.
    Inventors: Bernard Beall et al. U.S. Patent Application SN: To be 
assigned, filed 5.18.2001. (CDC Ref. #: I-039-00)

DNA Synthesis by the Cooperative Action of DNA Polymerase and 
Nuclease

    Confirmation of a diagnosis of an infectious agent usually depends 
upon the detection of the causative agent or its signature effect on 
the immune system. Nucleic acid detection methods offer the greatest 
sensitivity but depend upon specific hybridization of a primer or a 
probe, thus they can only be used to detect nucleic acids. This 
invention comprises a novel method of diagnostic detection which 
retains the sensitivity of nucleic acid based amplification methods 
while allowing detection of non-nucleic acid targets such as 
antibodies, surface proteins, or other antigenic components. Thus, no 
specific sequence information need be known about the potential target.
    Inventors: Yuri Khudyakov, U.S. Patent Application SN: (CDC Ref. #: 
I-043-00)

[[Page 34455]]

BACTID--Microcomputer Programs and Databases for the Identification 
of Enterobacteriaceae, Vibrionaceae, and Other Microorganisms

    BACTID consists of a software program coupled with a database 
whereby the user enters a description of an unknown microorganism which 
the software compares to the database for the purpose of identification 
of the unknown. This program allows regional diagnostic labs to access 
national databases which provide for greater sensitivity and 
specificity in identification of unknowns without the need to transfer 
samples to larger labs.
    Inventor: John J. Farmer, U.S. Patent Application SN: Application 
yet to be filed. (CDC Ref. #: I-045-00)

    Dated: June 22, 2001.
Joseph R. Carter,
Associate Director for Management and Operation, Centers for Disease 
Control and Prevention.
[FR Doc. 01-16245 Filed 6-27-01; 8:45 am]
BILLING CODE 4163-18-P


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