Exhibit 10.5


 





THIS WARRANT AND THE SECURITIES UNDERLYING
THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”) AND MAY NOT BE OFFERED,
SOLD OR OTHERWISE TRANSFERRED, ASSIGNED, PLEDGED, OR HYPOTHECATED IN THE ABSENCE OF SUCH REGISTRATION OR AN EXEMPTION THEREFROM
UNDER SUCH SECURITIES ACT, ANY APPLICABLE STATE SECURITIES LAWS AND THE RULES AND REGULATIONS THEREUNDER. 


 


PROTEA BIOSCIENCES GROUP, INC.


 


WARRANT


 


TO PURCHASE COMMON STOCK OF THE COMPANY


 


	Warrant No. [   ]	 	Issue Date: January __, 2016


 


FOR VALUE RECEIVED,
PROTEA BIOSCIENCES GROUP, INC., a Delaware corporation (the “Company”), grants the following rights
to West Virginia Jobs Investment Trust Board and its permitted assigns, heirs, executors and administrators (individually
and collectively, the “Holder”), as of the __ day of January, 2016 (the “Issue Date”).


 


		Section 1.	Grant.



 


The Holder is hereby
granted the right (collectively, the “Purchase Rights”), in accordance with the terms and conditions
of this Warrant, from the date hereof until the expiration of the Exercise Period (as defined in Section 3.1 hereof), to purchase
from the Company that number of fully paid and non-assessable shares of the common stock, par value $0.0001 per share (the “Common
Stock”) of the Company, set forth in Section 2 hereof, at the Exercise Price (as defined in Section 5 hereof), upon
delivery to the Company of this Warrant along with the Notice of Exercise form attached as Exhibit 1 hereto, duly executed,
and upon tender of the Exercise Price for the shares of Common Stock to be purchased, which Payment shall be made in cash, wire
transfer or bank cashier’s check.


 


		Section 2.	Number of Shares of Common Stock Purchasable.



 


2.1           Subject
to the other provisions of this Section 2, this Warrant entitles the Holder to purchase up to an aggregate of Five Hundred Ninety
Thousand (590,000) shares of the Company’s Common Stock (the “Warrant Shares”).


 


2.2           In
case prior to the expiration of the Purchase Rights by exercise or by the terms of this Warrant, the Company shall undertake any
reclassification, stock split, reverse stock split, stock dividend or any similar proportionately-applied change (collectively,
a “Reclassification”) of outstanding shares of Common Stock (other than a change solely in, of, or from
par value), the Holder shall thereafter be entitled, upon exercise of this Warrant for the same total consideration as presently
required, to purchase the kind and amount of shares of stock and other securities and property receivable upon such Reclassification
by a holder of the number of shares of Common Stock which this Warrant entitles the Holder hereof to purchase immediately prior
to such Reclassification. Notice of any such Reclassification shall be given to the Holder pursuant to Section 11 hereof.


 




     


     


    

  


2.3           In
case prior to the expiration of the Purchase Rights by exercise or by the terms of this Warrant, the Company shall determine to
consolidate or merge with, or convey all, or substantially all, of its property or assets to, any other corporation or corporations,
or to dissolve, liquidate or wind up, then, as a condition precedent to such consolidation, merger, conveyance, dissolution, liquidation
or winding up, notice shall be given to the Holder pursuant to Section 11 hereof and lawful and adequate provision shall be made
whereby the Holder shall thereafter have the right to receive from the Company or from the Company’s successors or assigns,
as the case may be, upon the basis and upon the terms and conditions specified in this Warrant, in lieu of the shares of Common
Stock of the Company theretofore purchasable upon the exercise of the Purchase Rights, such shares of stock, securities, or assets
as may be issued or payable with respect to, or in exchange for, the number of shares of Common Stock of the Company theretofore
purchasable upon the exercise of the Purchase Rights had such consolidation, merger, conveyance, dissolution, liquidation or winding-up
not taken place; and in any such event the rights of the Holder to an adjustment of the number of shares of Common Stock purchasable
upon the exercise of the Purchase Rights as herein provided, shall continue and be preserved in respect of any stock or securities
which the Holder becomes entitled to purchase.


 


		Section 3.	Exercise Period; Registration Statement Notice.



 


3.1           The
Purchase Rights represented hereby shall be exercisable in whole or in part from time to time, subject to the terms and conditions
set forth herein, after the Issue Date of this Warrant until the earlier of (i) a Qualified Public Offering or (ii) 5:00 p.m. Eastern
time on the fifth anniversary of the Issue Date hereof (the “Exercise Period”). For purposes of this
Warrant, the term “Qualified Public Offering” shall mean the closing of a firm underwritten offering
commitment pursuant to an effective registration statement under the Act covering the offer and sale of Common Stock for the account
of the Company in which the net cash proceeds to the Company (after deduction of underwriting discounts and commissions) are at
least $10,000,000.


 


3.2           The
Company shall give the Holder written notice of any Qualified Public Offering, at the address of the Holder set forth on the Company’s
books, at least twenty (20) days prior to the closing of such Qualified Public Offering.


 


		Section 4.	Exercise.



 


The Purchase Rights represented
by this Warrant are exercisable at the option of the Holder in whole or in part from time to time, subject to the terms and conditions
set forth herein, but not for less than 100 shares at a time, at any time and from time to time during the Exercise Period upon
the delivery of the Notice of Exercise form to the Company with such notice duly executed and upon tender of the Exercise Price
for the shares of Common Stock to be purchased, which Payment shall be made in cash, by wire transfer or bank cashier’s check.
The Purchase Rights shall be deemed to have been exercised, and the Holder shall be deemed to have become a stockholder of record
of the Company for the purposes of receiving dividends and for all other purposes whatsoever with respect to the shares of Common
Stock so purchased, as of the date of delivery of such properly executed notice accompanied by proper tender of the Exercise Price
at the principal office of the Company. As promptly as practicable on or after such date, and in any event within three (3) business
days thereafter, the Company at its expense shall issue and deliver, or cause to be issued and delivered, to the person or persons
entitled to receive the same, a certificate or certificates for the number of shares issuable upon such exercise. In the event
that this Warrant is exercised in part, the Company at its expense shall execute and deliver a new warrant of like tenor exercisable
for the number of shares for which this Warrant may then be exercised.


 


		Section 5.	Exercise Price.



 


The exercise price for
each share of Common Stock issuable to the Holder hereunder shall be $0.40 per share subject to adjustment hereunder (the “Exercise
Price”).


 




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		Section 6.	Company’s Warranties and Covenants as to
Capital Stock.



 


The Company has taken
all action necessary and appropriate to properly authorize, reserve and issue those shares of Common Stock issuable to the Holder
pursuant to this Warrant including an authorization of issuance and setting of the Exercise Price. The Common Stock deliverable
on the exercise of the Purchase Rights represented hereby shall, when issued, be duly and validly issued, fully paid and non-assessable.
The Company shall at all times reserve and hold available sufficient shares of Common Stock to satisfy all Purchase Rights hereby
granted.


 


		Section 7.	Transfer; Compliance with Securities Laws



 


The Purchase Rights shall
be registered on the books of the Company, which shall be kept by it at its principal office for that purpose. This Warrant and
the Common Stock issuable upon exercise of the Purchase Rights, may not be transferred or assigned in whole or in part without
compliance with all applicable federal and state securities laws by the transferor and the transferee, including, if requested
by the Company, an opinion of counsel satisfactory to the Company to the effect that the transfer or assignment is in compliance
with applicable federal and state securities laws. Subject to such compliance, the Purchase Rights shall be transferable on said
books, in whole or in part, by the Holder in person or by duly authorized attorney upon surrender of this Warrant properly endorsed
by the Holder executing the Permitted Transfer or Assignment Form attached hereto and made a part hereof as Exhibit 2. All
reasonable and documented costs associated with any transfer or assignment, including, without limitation, the reasonable fees
of counsel to the Company shall be borne by the transferor or assignor. The Company agrees that, while the Purchase Rights remain
valid and outstanding, its stock transfer books shall not be closed for any purpose whatsoever except under arrangements which
shall insure to persons exercising warrants or applying for transfer of stock, all rights and privileges which they might have
had or received if the stock transfer books had not been closed and they had exercised their Purchase Rights at any time during
which such transfer book shall have been closed.


 


		Section 8.	Charges, Taxes and Expenses.



 


Issuance of certificates
for shares of Common Stock issuable upon the exercise of this Warrant or any portion thereof (and issuance of a replacement warrant
certificate in the event of partial exercise) shall be made without charge to the Holder hereof for any issue taxes or any other
incidental expenses in respect of the issuance of such certificates to and in the name of the registered Holder of this Warrant,
all of which taxes and expenses shall be paid by the Company. Certificates may be issued in a name other than that of the Holder
upon the request of and payment by the Holder of any applicable transfer taxes and compliance with all applicable federal and state
securities laws and with all applicable provisions of this Warrant, including but not limited to Section 7 hereof.


 


		Section 9.	Exchange for Other Denominations.



 


This Warrant is exchangeable
for new certificates of like tenor and date representing in the aggregate the right to purchase the number of shares purchasable
hereunder in denominations designated by the Holder at the time of surrender. In the event of the purchase, at any time prior to
the expiration of the Exercise Period, of less than all of the shares of Common Stock purchasable hereunder, the Company shall
cancel this Warrant upon surrender thereof, and shall promptly execute and deliver to the Holder hereof a new warrant of like tenor
and date for the balance of the shares purchasable hereunder.


 




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		Section 10.	Loss, Theft, Destruction or Mutilation of Warrant.



 


Upon receipt by the Company
of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant, and, in case
of loss, theft or destruction, of indemnity or security reasonably satisfactory to it, and upon reimbursement to the Company of
all reasonable and documented expenses incidental thereto, and upon surrender of this Warrant, if mutilated, the Company shall
promptly make and deliver a new warrant of like tenor and date, in lieu of this Warrant and shall cancel this Warrant.


 


		Section 11.	Notices Including Certificate of Company in Event
of Adjustment.



 


(a)          Whenever
the number of shares of Common Stock purchasable hereunder shall be adjusted pursuant to Sections 2 hereof, the Company shall issue
a certificate signed by its Chief Financial Officer or its President or by such other appropriate officer, setting forth, in reasonable
detail, the event requiring the adjustment, the amount of the adjustment, the method by which such adjustment was calculated, and
the number of shares purchasable hereunder after giving effect to such adjustment, and shall cause a copy of such certificate to
be mailed (by first-class mail, postage prepaid) to the Holder of this Warrant.


 


(b)          In
case:


 


(i)          the
Company shall take a record of the holders of its Common Stock for the purpose of entitling them to receive any dividend or other
distribution, or any right to subscribe for or purchase any shares of stock of any class or any other securities, or to receive
any other right; or


 


(ii)         of
any capital reorganization of the Company, any reclassification of the capital stock of the Company, any consolidation or merger
of the Company with or into another corporation, or any conveyance of all or substantially all of the assets of the Company to
another entity; or


 


(iii)        of
any voluntary dissolution, liquidation or winding-up of the Company;then, and in each such case under subclauses (i) through (iii),
the Company shall mail or deliver, or cause to be mailed or delivered, to the Holder a notice specifying, as the case may be, (A)
the date on which a record is to be taken for the purpose of such dividend, distribution or right, and stating the amount and character
of such dividend, distribution or right; or (B) the date on which such reorganization, reclassification, consolidation, merger,
conveyance, dissolution, liquidation or winding-up is to take place, and the time, if any is to be fixed, at which the holders
of record of Common Stock shall be entitled to exchange their shares of Common Stock for securities, assets or other property of
the Company deliverable upon such reorganization, reclassification, consolidation, merger, conveyance, dissolution, liquidation
or winding-up. Such notice shall be mailed or delivered at least fifteen (15) business days prior to the date therein specified.


 


(c)          All
notices, requests, consents and demands required by this Warrant shall be in writing and shall be personally delivered or mailed,
postage prepaid, to the principal office of the Company at:


 


	 	PROTEA BIOSCIENCES GROUP, INC.	 
	 	1301 Pineview Drive, Suite 501	 
	 	Morgantown, WV 26505	 
	 	Attn:  President	 
	 	Fax:  304-292-7101	 


 




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with a copy (which shall not constitute
notice) to:


 


	 	CKR Law LLP	 
	 	1330 Avenue of the Americas	 
	 	New York, New York 10019	 
	 	Attn:  Barrett S. DiPaolo	 
	 	Fax:  212-259-8200	 


 


and to the Holder at:


 


	 	West Virginia Jobs Investment Trust Board	 
	 	[Address]	 
	 	Attn: C. Andrew Zulauf	 
	 	Fax: [      ]	 


 


Any notice, request or other communication
required or permitted hereunder shall be in writing and shall conclusively be deemed to have been duly given: (i) upon personal
delivery to the party to be notified, (ii) when sent by confirmed facsimile if sent during the normal business hours of the recipient,
if not, then on the next business day, (iii) five (5) days after having been sent by registered or certified mail, return receipt
requested, postage prepaid, or (iv) one (1) day after deposit with a nationally recognized overnight courier, specifying next day
delivery with written verification of receipt.


 


		Section 12.	Miscellaneous



 


(a)          No
Stockholder Rights. Nothing contained in this Warrant shall be construed as conferring upon the Holder or any other person
the right to vote, consent or receive notice as a stockholder in respect of any meeting of stockholders for the election of directors
of the Company or any other matters, or any other rights whatsoever of a stockholder of the Company.


 


(b)          Successors
and Assigns. Subject to the restrictions on transfer described in Section 7 hereof, the rights and obligations of the Company
and the Holder of this Warrant shall be binding upon, and benefit the successors and assigns of, the parties hereto.


 


(c)          Governing
Law. In all respects, including all matters of construction, validity and performance, this Warrant shall be governed by, and
construed and enforced in accordance with, the laws of the State of Delaware, without regard to principles thereof relating to
conflicts or choice of law.


 


(d)          Waiver
and Amendment. This Warrant may be changed, waived, discharged or terminated only by a statement in writing signed by the party
against which enforcement of such change, waiver, discharge or termination is sought. In case any provision of this Warrant shall
be, in whole or in part, invalid, illegal or unenforceable, such provision shall be enforced to the extent, if any, that it may
legally be enforced and the validity, legality and enforceability of the remaining provisions shall not in any way be affected
or impaired thereby.


 


(e)          Headings;
References. All headings used herein are used for convenience only and shall not be used to construe or interpret this Warrant.
Except where otherwise indicated, all references herein to Sections refer to Sections hereof. 


 


[Signatures appear on following page.]


 




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IN WITNESS WHEREOF, the
Company has caused this Warrant to be duly executed, under seal and delivered on its behalf as of the Issue Date set forth above.


 


	 	PROTEA BIOSCIENCES GROUP, INC.
	 	 	 
	 	By:	/s/ Stephen Turner
	 	 	Stephen Turner
	 	 	President


 




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EXHIBIT 1


 


NOTICE OF EXERCISE PURSUANT TO


ATTACHED WARRANT


 





	 	 	, 20	 	 




 


To: PROTEA BIOSCIENCES GROUP, INC.


 


(1)         The
undersigned, the Holder of record of the attached Warrant of PROTEA BIOSCIENCES GROUP, INC., hereby exercises the option granted
by the Purchase Rights evidenced by the attached Warrant [and hereby tenders payment of the Exercise Price as determined by the
Warrant] [on a “cashless” basis as permitted by Section 4.2 of the Warrant] to purchase upon the terms set forth in
such Warrant [________] shares of Common Stock, which constitutes all [or a portion] of the shares of Common Stock issued pursuant
to the Purchase Rights represented by this Warrant of PROTEA BIOSCIENCES GROUP, INC. All capitalized terms used but not defined
in this notice have the meanings assigned to such terms in the Warrant.


 


(2)         In
exercising this Warrant, the undersigned hereby confirms and acknowledges that (a) the undersigned is an “accredited investor”
as defined in Rule 501 under the Securities Act of 1933, as amended (the “Securities Act”), (b) the shares of the Common
Stock to be issued are being acquired solely for investment and solely for the account of the undersigned, (c) the undersigned
will not offer, sell or otherwise dispose of any such shares of Common Stock except under circumstances that will not result in
a violation of the Securities Act or any applicable state securities laws, and (d) the certificate or certificates representing
said shares of Common Stock shall bear a restrictive legend prohibiting and restricting transfer of such shares except in compliance
with applicable federal and state securities laws.


 


(3)         Please
issue a certificate or certificates representing said shares of Common Stock in the name of the undersigned or in such other name
as is specified below.


 


(4)         Please
issue a new Warrant for the unexercised portion of the attached Warrant, if any, in the name of the undersigned or in such other
name as is specified below:


 


	ATTEST:	 	HOLDER:	 
	 	 	 	 
	 	 	By:	 
	 	 	 	 
	 	 	Name:	 
	 	 	 	 
	 	 	Title:	 


 


(If certificates for Common Stock or new
Warrants are requested in a name other than the undersigned, be advised that the delivery of the certificates and/or new Warrants
will be delayed until the Company assures itself that such change is permitted under Section 7 of the Warrant that such change
does not violate applicable federal and state securities laws.)


 




     


     


    

  


EXHIBIT 2


 


PERMITTED TRANSFER OR ASSIGNMENT FORM


 


NOTE: THIS ASSIGNMENT BEARS A RESTRICTIVE
LEGEND BELOW


 


FOR VALUE RECEIVED,
the undersigned Holder of record of this Warrant of PROTEA BIOSCIENCES GROUP, INC. (the “Company”), which is dated
___________, hereby sells, assigns and transfers unto the Assignee named below all of the rights, including, without limitation,
the Purchase Rights (as such term is defined in this Warrant) of the undersigned under the within Warrant, with respect to the
number of shares of Common Stock set forth below:


 


	Name of Transferee/Assignee	Address	No. of Shares
	 	 	 


 


and does hereby irrevocably constitute
and appoint the Secretary of PROTEA BIOSCIENCES GROUP, INC. to make such transfer on the books of PROTEA BIOSCIENCES GROUP, INC.,
maintained for the purpose, with full power of substitution in the premises.


 


Attached hereto, if
and to the extent requested by the Company, is an opinion of counsel that the assignment does not violate or is exempt from, any
federal and state securities laws. As provided in the Warrant, including but not limited to Section 7 of the Warrant, the Company
may, in its sole discretion, decide whether such opinion is satisfactory, and Assignee and Holder agree to any reasonable delay
in transfer caused by such evaluation and further acknowledge and agree that they shall bear all reasonable and documented costs
associated with any transfer or assignment, including, without limitation, the reasonable fees of counsel to the Company shall
be borne by the transferor or assignor.


 


The undersigned also
represents that, by assignment hereof, the Assignee acknowledges that this Warrant and the shares of Common Stock to be issued
upon exercise hereof or conversion thereof are being acquired for investment and that the Assignee will not offer, sell or otherwise
dispose of this Warrant or any shares of stock to be issued upon exercise hereof or conversion thereof except under circumstances
which will not result in a violation of the Securities Act of 1933, as amended (the “Act”), or any state securities
laws. Further, the Assignee has acknowledged that upon exercise of this Warrant, the Assignee shall, if requested by the Company,
confirm in writing, in a form satisfactory to the Company, that the shares of Common Stock so purchased are being acquired for
investment and not with a view toward distribution or resale in violation of applicable securities laws.


 


Accordingly, the
following restrictive legend is made applicable to this assignment (and to this Warrant and securities covered by this Warrant
as assigned hereby to Assignee):


 


This Assignment and this Warrant and
the securities underlying this Warrant as assigned hereby, have not been registered under the Act, and may not be offered, sold
or otherwise transferred, assigned, pledged or hypothecated in the absence of such registration or an exemption therefrom under
such Act, any applicable state securities laws and the rules and regulations thereunder.


 


[Signatures appear on following page.]


 




     


     


    

  


	Dated: 	 	 	HOLDER:	 
	 	 	 	 	 
	 	 	 	By:	 
	 	 	 	Name:	 
	 	 	 	Title:	 
	 	 	 	 	 
	Dated:	 	 	ASSIGNEE: 	 
	 	 	 	 	 
	 	 	 	By:	 
	 	 	 	Name:	 
	 	 	 	Title:	 


 




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