Federal Register / Vol. 66, No. 119 / Wednesday, June 20, 2001 / Notices 33103

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

Health Care Financing Administration

[Document Identifier: HCFA–SP1]

Agency Information Collection

Activities: Submission for OMB

Review; Comment Request

AGENCY: Health Care Financing

Administration, HHS.

In compliance with the requirement

of section 3506(c)(2)(A) of the

Paperwork Reduction Act of 1995, the

Health Care Financing Administration

(HCFA), Department of Health and

Human Services, is publishing the

following summary of proposed

collections for public comment.

Interested persons are invited to send

comments regarding this burden

estimate or any other aspect of this

collection of information, including any

of the following subjects: (1) The

necessity and utility of the proposed

information collection for the proper

performance of the agency’s functions;

(2) the accuracy of the estimated

burden; (3) ways to enhance the quality,

utility, and clarity of the information to

be collected; and (4) the use of

automated collection techniques or

other forms of information technology to

minimize the information collection

burden.

Type of Information Collection

Request: Extension of a currently

approved collection; Title of

Information Collection: Medicaid PostEligibility Preprint and Supporting

Regulations in 42 CFR 435.310; Form

No.: HCFA–SP–0001 (OMB# 0938–

0673); Use: The post-eligibility preprint

is part of the comprehensive statement

that a State submits to show that it is

meeting the requirements for Federal

funding of its Medicaid program. It

comprises part of each State’s Plan

which outlines the mandatory and

optional aspects of a State’s Medicaid

program. Accurate submission of this

information is necessary in order for

States to receive federal funding;

Frequency: On occasion; Affected

Public: State, local or tribal government;

Number of Respondents: 13; Total

Annual Responses: 5; Total Annual

Hours: 15.

To obtain copies of the supporting

statement and any related forms for the

proposed paperwork collections

referenced above, access HCFA’s Web

Site address at http://www.hcfa.gov/

regs/prdact95.htm, or E-mail your

request, including your address, phone

number, OMB number, and HCFA

document identifier, to

Paperwork@hcfa.gov, or call the Reports

Clearance Office on (410) 786–1326.

Written comments and

recommendations for the proposed

information collections must be mailed

within 30 days of this notice directly to

the OMB desk officer: OMB Human

Resources and Housing Branch,

Attention: Wendy Taylor, New

Executive Office Building, Room 10235,

Washington, DC 20503.

Dated: May 29, 2001.

John P. Burke, III,

HCFA Reports Clearance Officer, HCFA Office

of Information Services, Security and

Standards Group, Division of HCFA

Enterprise Standards.

[FR Doc. 01–15451 Filed 6–19–01; 8:45 am]

BILLING CODE 4120–03–P

DEPARTMENT OF HEALTH AND

HUMAN SERVICES

National Institutes of Health

National Institute of Environmental

Health Sciences; Proposed Collection;

Comment Request; The Sister Study: A

Prospective Study of the Genetic and

Environmental Risk Factors for Breast

Cancer

SUMMARY: In compliance with the

requirement of section 3506(c)(2)(A) of

the Paperwork Reduction Act of 1995,

for opportunity for public comment on

proposed data collection projects, the

National Institute of Environmental

Health Sciences (NIEHS), the National

Institutes of Health (NIH) will publish

periodic summaries of proposed

projects to be submitted to the Office of

Management and Budget (OMB) for

review and approval.

Proposed Collection: Title: The Sister

Study: A Prospective Study of the

Genetic and Environmental Risk Factors

for Breast Cancer.

Type of Information Collection

Request: NEW. Need and Use of

Information Collection: We are

proposing to study genetic and

environmental risk factors for the

development of breast cancer in a cohort

of sisters of women who have had breast

cancer. In the United States, there were

approximately 180,000 new cases in

1997, accounting for 30% of all new

cancer cases among women. The

etiology of breast cancer is complex,

with both genetic and environmental

factors likely playing a role.

Environmental risk factors, however,

have been difficult to identify. By

focusing on genetically susceptible

subgroups, more precise estimates of the

contribution of environmental and other

non-genetic factors to disease risk may

be possible. Sisters of women with

breast cancer are one group at increased

risk for breast cancer; we would expect

about 2 times as many breast cancers to

accrue in a cohort of sisters as would

accrue in a cohort identified through

random sampling or other means.

Sisters of women with breast cancer will

also be at increased risk for ovarian

cancer and possibly for other

hormonally-mediated diseases. The

sister design will also facilitate study of

sib-pairs to evaluate similarities in

tumor characteristics, prognosis, and

risk factors. We propose to enroll a

cohort of 50,000 women who have not

had breast cancer. In addition, we will

enroll 500 of the index sisters whose

breast cancer diagnosis was within the

past four months. Initial recruitment of

the first 2,000 women will take place

from October 2001–January 2002 before

beginning recruitment in earnest in

April 2002. The data collected in the

initial phase will allow us to evaluate

subject recruitment and data collection

procedures, and collect other data that

will help us better target our

recruitment efforts. We estimate that a

cohort of 50,000 sisters aged 30–74

years would provide about 1,500 breast

cancer cases over five years.

Frequency of Response: On occasion

(one initial 15-minute screening [either

on the telephone OR on the internet],

followed by an hour and a half-long

telephone interview, one mailed selfadministered questionnaire, and some

biological specimens collection).

Women will be advised that subsequent

shorter interviews or questionnaires will

be sought every 1–2 years for follow-up.

Affected Public: Individuals or

households.

Type of Respondents: Unaffected

sisters of women diagnosed with breast

cancer, aged 30–74, from all

socioeconomic backgrounds and

ethnicities and women with recently

diagnosed breast cancer. The annual

reporting burden is as follows:

Estimated Number of Respondents:

63,000 (20,833 unaffected sisters per

year, on average, plus a total of 500

index sisters with incident breast

cancer).

Estimated Number of Responses per

Respondent: See table below.

Average Burden Hours Per Response:

4.6; and

Estimated Total Burden Hours

Requested: 293,500 (over 3 years). The

average annual burden hours requested

is 97,833. The annualized cost to

respondents is estimated at $115

(assuming $20 hourly wage × 5 hours +

$15 babysitting/travel allowance). There

are no Capital Costs to report. There are

no Operating or Maintenance Costs to

report.