UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

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# FORM 8-K

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# CURRENT REPORT

# PURSUANT TO SECTION 13 OR 15(d) OF
THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (date of earliest event reported): November 13, 2006

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CNS, Inc.
(Exact name of Registrant as Specified in its Charter)

Delaware
(State Or Other Jurisdiction Of Incorporation)

|0-16612                  | 41-1580270                          
|------------------------ | ------------------------------------
|(Commission File Number) | (I.R.S. Employer Identification No.)

|7615 Smetana LaneEden Prairie, MN        | 55344     
|---------------------------------------- | ----------
|(Address Of Principal Executive Offices) | (Zip Code)

(952) 229-1500
Registrants Telephone Number, Including Area Code

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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (seeGeneral Instruction A.2. below):



| | o |  | Written communications pursuant to Rule 425 under the Securities
Act (17 CFR 230.425)
| | - |  | -------------------------------------------------------------------------------------

| | x |  | Soliciting material pursuant to Rule 14a-12 under the Exchange Act
(17 CFR 240.14a-12)
| | - |  | --------------------------------------------------------------------------------------

| | o |  | Pre-commencement communications pursuant to Rule 14d-2(b) under
the Exchange Act (17 CFR 240.14d-2(b))
| | - |  | ------------------------------------------------------------------------------------------------------

| | o |  | Pre-commencement communications pursuant to Rule 13e-4(c) under
the Exchange Act (17 CFR 240.13e-4(c))
| | - |  | ------------------------------------------------------------------------------------------------------







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Items under Sections 2 through 8 are not applicable and therefore omitted.



Item 1.01   Entry into a Material Definitive Agreement



As previously reported, on October 8, 2006,
CNS, Inc. (the Company), GlaxoSmithKline plc (GSK), and Platform Acquisition Corporation, a Delaware
corporation and indirect wholly owned subsidiary of GSK (the Merger Sub), entered into an Agreement and Plan of Merger
(the Merger Agreement), providing for the merger of Merger Sub with and into the Company, with the Company surviving
as a wholly-owned subsidiary of GSK (the merger).



On November 13, 2006, the Company, GSK, and Merger Sub
entered into Amendment No. 1 to Agreement and Plan of Merger (the Amendment). The Amendment amends the Merger
Agreement to provide that, for the purposes of calculating certain post-merger payments by the Company to its employees under the
Companys 2007 Incentive Plan, the adjusted performance period to be used with respect to operating income will end on
December 31, 2006 if the effective time of the merger occurs on or before that date.



The foregoing description of the Amendment does not
purport to be complete and is qualified in its entirety by reference to the Amendment, which is filed as Exhibit 2.1 hereto,
and is incorporated by reference herein.



Important Merger Information



On October 30, 2006, the Company filed a preliminary
proxy statement with the SEC in connection with a special meeting of stockholders to approve the proposed merger with
GlaxoSmithKline plc. Stockholders and investors are advised to read the definitive proxy statement and any other definitive
additional soliciting materials when they become available because they will contain important information about the merger and
the Company. Stockholders and investors may obtain a free copy of these proxy materials and other documents filed by the
Company with the SEC at the SECs web site at www.sec.gov. Free copies of the definitive proxy statement, once
available, and the Companys other filings with the SEC, may also be obtained from the Company at www.cns.com by
clicking on the Investors tab and then following the link at Financial Information to SEC
Filings. Free copies of the Companys filings may be obtained by directing a written request to CNS, Inc.,
7615 Smetana Lane, Eden Prairie, Minnesota 55344, Attention: Samuel E. Reinkensmeyer or by telephone at 952-229-1500.



Participants in the Solicitation



The Company and its directors, executive officers and
certain other members of its management may be deemed to be soliciting proxies from the Companys stockholders in favor
of the merger. Investors and stockholders may obtain more detailed information regarding the direct and indirect interests in
the merger of persons who may, under the rules of the SEC, be considered participants in the solicitation of the Companys
stockholders in connection with the merger by reading the preliminary and definitive proxy statements regarding the merger, which
will be filed with the SEC. Information about the Companys directors and executive officers may be found in the
Companys preliminary proxy statement filed on October 30, 2006 and definitive proxy statement filed with the SEC on
July 7, 2006. These documents are available free of charge once available at the SECs web site at
www.sec.gov or by directing a request to the Company as described above.



Item 9.01   Financial Statements and Exhibits



Exhibit No.
        
        Description2.1
        
        Amendment No. 1 to Agreement and Plan of Merger dated as of November 13, 2006 among GlaxoSmithKline plc, Platform Acquisition Corporation and CNS, Inc.








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SIGNATURE



Pursuant to the requirements of the
Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned,
thereunto duly authorized.





| | CNS, INC.                                         
| | --------------------------------------------------
| |                                                   
| | By:                                               
| | Marti MorfittPresident and Chief Executive Officer

Date:  November 16, 2006

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