|As filed with the Securities and Exchange Commission on November 4, 2005 |  | Registration No. 333-_____________ | 
|------------------------------------------------------------------------ |  | ---------------------------------- | 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

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FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

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CNS, INC.
(Exact name of registrant as specified in its charter)

|Delaware                                                       |  | 41-1580270                           | 
|-------------------------------------------------------------- |  | ------------------------------------ | 
|(State or other jurisdiction of incorporation or organization) |  | (I.R.S. Employer Identification No.) | 

7615 Smetana Lane
Eden Prairie, Minnesota 55344
(Address of principal executive offices and zip code)

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CNS, INC.
2000 Stock Option Plan
(Full title of the Plan)

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|                                           |  | Copy to:                    | 
|------------------------------------------ |  | --------------------------- | 
|Marti Morfitt                              |  | Charles P. Moorse           | 
|CNS, Inc.                                  |  | Lindquist & Vennum P.L.L.P. | 
|7615 Smetana Lane                          |  | 4200 IDS Center             | 
|Eden Prairie, Minnesota 55344              |  | 80 South 8th Street         | 
|(952) 229-1500                             |  | Minneapolis, MN 55402       | 
|(Name, address and telephone number,       |  | (612) 371-3211              | 
|including area code, of agent for service) | 

CALCULATION OF REGISTRATION FEE


|                            
|----------------------------
|
|                            
|Common Stock,               
|$.01 par value, to be issued
|pursuant to CNS, Inc. 2000  
|Stock Option Plan           
|                            

|_________________
|-----------------
|(1)              

|(2) | 700,000 shares of Common Stock were originally registered on Form
S-8 (File No. 333-42108) filed on July 24, 2000; 650,000 shares of Common Stock were registered on Form S-8 (File No. 333-109110)
filed on September 25, 2003 and 1,200,000 additional shares of Common Stock are being registered herewith
|--- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------





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INCORPORATION OF CONTENTS OF REGISTRATION STATEMENT
BY REFERENCE

A Registration Statement on
Form S-8 (File No. 333-42108) was filed with the Securities and Exchange Commission on July 24, 2000 covering the registration of
700,000 shares of Common Stock initially authorized for issuance under the CNS, Inc. 2000 Stock Option Plan (the
Plan). A Registration Statement on Form S-8 (File No. 333-109110) was filed with the Securities and Exchange
Commission on September 25, 2003 covering the registration of 650,000 additional shares of Common Stock authorized for issuance
under the Plan. Pursuant to General Instruction E of Form S-8 and Rule 429, this Registration Statement is being filed to register
an additional 1,200,000 shares authorized under the Plan. An amendment to the Plan to increase the reserved and authorized number
of shares under the Plan by 1,200,000 was authorized by the Companys Board of Directors on June 22, 2005 and such amendment
was approved by the Companys stockholders on August 30, 2005. This Registration Statement should be considered a
post-effective amendment to the prior Registration Statement. The contents of the prior Registration Statement are incorporated
herein by reference.

PART I

Pursuant to Part I of Form
S-8, the information required by Items 1 and 2 of Form S-8 is not filed as a part of this Registration Statement.

PART II

Item 3.    Incorporation of Documents by Reference.

The following documents filed
with the Securities and Exchange Commission are hereby incorporated by reference:

| | (a) |  | The Annual Report of the Company on Form 10-K for the year ended
March 31, 2005.
| | --- |  | --------------------------------------------------------------------------------

| | (b) |  | The Quarterly Reports of the Company on Form 10-Q for the quarters
ended June 30, 2005 and September 30, 2005; the Definitive Proxy Statement dated July 12, 2005 for the 2005 Annual Meeting of
Stockholders held on August 30, 2005.
| | --- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | (c) |  | The description of the Companys Common Stock to be offered
pursuant to this Registration Statement is incorporated by reference to the Companys Registration Statement on Form 8-A/A
(File No. 000-16612), including any amendment or report filed for the purpose of updating such description.
| | --- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

All documents subsequently
filed by the Company pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Securities Exchange Act of 1934 prior to the
completion or termination of this offering of shares of Common Stock shall be deemed to be incorporated by reference in this
Registration Statement and to be a part hereof from the date of filing of such documents.

1

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Item 4.    Description of Securities.

Not applicable.

Item 5.    Interests of Named Experts and Counsel.

Not applicable

Item 6.    Indemnification of Directors and Officers.

The Companys Bylaws
require indemnification of directors and officers of the Company in accordance with, and to the fullest extent permitted by,
Delaware law, as it may be amended from time to time.

Section 145 of the Delaware
General Corporation Law generally provides that any person who was or is a director or officer may be indemnified against expenses
(including attorneys fees), judgments, fines and amounts paid in settlement actually and reasonably incurred in connection
with the defense or settlement of any threatened, pending or completed legal proceedings in which he is involved by reason of the
fact that he is or was a director or officer if he acted in good faith and in a manner that he reasonably believed to be in or not
opposed to the best interests of the corporation, and, with respect to any criminal action or proceeding, if he had no reasonable
cause to believe that his conduct was unlawful. However, if the legal proceeding is by or in the right of the corporation, the
director or officer may not be indemnified in respect of any claim, issue or matter as to which he shall have been adjudged to be
liable to the corporation unless the court in which such action was brought deems it proper.

The Company maintains
directors and officers liability insurance, including a reimbursement policy in favor of the Company.

The Company has been advised
that, in the opinion of the Securities and Exchange Commission, indemnification for liabilities arising under the Securities Act
that may be permitted to our directors, officers and controlling persons pursuant to the foregoing provisions, or otherwise, is
against public policy as expressed in the Securities Act and is, therefore, unenforceable.

Item 7.    Exemption from Registration Claimed.

Not applicable.

2

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Item 8.    Exhibits.

| | Exhibit
| | -------

| | 4.1 |  | CNS, Inc. 2000 Stock Option Plan, as amended through August 30, 2005
| | --- |  | --------------------------------------------------------------------

| | 5.1 |  | Opinion of Lindquist & Vennum P.L.L.P.
| | --- |  | --------------------------------------

| | 23.1 |  | Consent of Lindquist & Vennum P.L.L.P. (included in Exhibit 5.1)
| | ---- |  | ----------------------------------------------------------------

| | 23.2 |  | Consent of KPMG LLP, independent registered public accounting firm
| | ---- |  | ------------------------------------------------------------------

| | 24.1 |  | Power of Attorney (included on signature page)
| | ---- |  | ----------------------------------------------

Item 9.    Undertakings.

The Company hereby undertakes to:

(a)    (1)    File, during any period
in which offers or sales are being made, a post-effective amendment to this registration statement to:

| | (i)       Include
any material information with respect to the plan of distribution not previously disclosed in the registration statement or any
material change to such information in the registration statement.
| | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

(2)       That,
for the purpose of determining any liability under the Securities Act of 1933, each such post-effective amendment shall be deemed
to be a new registration statement relating to the securities offered therein, and the offering of the securities at that time
shall be deemed to be the initial bona fide offering thereof.

(3)       To
remove from registration by means of a post-effective amendment any of the securities that remain unsold at the termination of the
offering.

(b)    The Company hereby undertakes that, for purposes
of determining any liability under the Securities Act of 1933, each filing of the Companys annual report pursuant to Section
13(a) or 15(d) of the Securities Exchange Act of 1934 (and, where applicable, each filing of an employee benefit plans
annual report pursuant to Section 15(d) of the Securities Exchange Act of 1934) that is incorporated by reference in the
Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the
offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

(c)    Insofar as indemnification for liabilities arising
under the Securities Act of 1933 may be permitted to directors, officers, and controlling persons of the issuer pursuant to the
foregoing provisions, or otherwise, the registrant has been advised that in the opinion of the Securities and Exchange Commission
such indemnification is against public policy as expressed in the Act and is, therefore, unenforceable. In the event that a claim
for indemnification against such liabilities (other than the payment by the registrant of expenses incurred or paid by a director,
officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such
director, officer, or controlling person in connection with the securities being registered, the registrant will, unless in the
opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the
question whether such indemnification by it is against public policy as expressed in the Act and will be governed by the final
adjudication of such issue.

3

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# SIGNATURES

Pursuant to the requirements
of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the city of Eden Prairie, state of Minnesota, on November 4, 2005.

| | CNS, INC.
| | ---------
|
| | By:      
| |          
|

# POWER OF ATTORNEY

The undersigned officers and
directors of CNS, Inc. hereby constitute and appoint Marti Morfitt with power to act as our true and lawful attorney-in-fact and
agent, with full power of substitution and resubstitution, for us and in our stead, in any and all capacities to sign any and all
amendments (including post-effective amendments) to this Registration Statement and all documents relating thereto, and to file
the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission,
granting unto said attorney-in-fact and agent, full power and authority to do and perform each and every act and thing necessary
or advisable to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his or her substitutes, may lawfully do or cause to
be done by virtue hereof.

Pursuant to the requirements
of the Securities Act of 1933, this registration statement has been signed below by the following persons in the capacities
indicated on November 4, 2005.

|Signature                 
|--------------------------
|                          
|/s/   Marti Morfitt       
|                          
|Marti Morfitt             
|                          
|/s/   Samuel Reinkensmeyer
|                          
|Samuel Reinkensmeyer      
|                          
|/s/   Daniel E. Cohen     
|                          
|Daniel E. Cohen           
|                          
|/s/   Karen Beckwith      
|                          
|Karen Beckwith            
|                          
|/s/   Patrick Delaney     
|                          
|Patrick Delaney           
|                          
|/s/   Andrew Greenshields 
|                          
|Andrew Greenshields       
|                          

4

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|Signature                
|-------------------------
|                         
|/s/   H. Robert Hawthorne
|                         
|H. Robert Hawthorne      
|                         
|/s/   Richard W. Perkins 
|                         
|Richard W. Perkins       
|                         
|/s/   Morris J. Siegel   
|                         
|Morris J. Siegel         
|                         

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