Exhibit 10.1




 


$50,000,000



 


Fluidigm Corporation



 


5.25% Convertible Senior Notes due 2024



 


PURCHASE AGREEMENT


 


November 20, 2019






 


Barclays Capital Inc.

As Representative of the several


Initial Purchasers named in Schedule I attached hereto,


745 Seventh Avenue

New York, New York 10019


 


Ladies and Gentlemen:


 


Fluidigm Corporation,
a Delaware corporation (the “Company”), proposes, upon the terms and conditions set forth in this agreement
(this “Agreement”), to issue and sell to you, as the initial purchasers (the “Initial Purchasers”)
for whom Barclays Capital Inc. (“Barclays”) is acting as representative (in such capacity, the “Representative”),
$50,000,000 in aggregate principal amount of its 5.25% convertible senior notes due 2024 (the “Firm Notes”).
The Firm Notes will (i) have terms and provisions that are summarized in the Offering Memorandum (as defined herein), and (ii)
are to be issued pursuant to an Indenture (the “Indenture”) to be entered into between the Company and
U.S. Bank, National Association, as trustee (the “Trustee”). The Company also proposes to issue and sell
to the Initial Purchasers, not more than an additional $5,000,000 of its 5.25% convertible senior notes due 2024 (the “Additional
Notes”) if and to the extent that the Initial Purchasers shall have determined to exercise the right to purchase
such 5.25% convertible senior notes due 2024 granted to the Initial Purchasers in Section 3(b) hereof. The Firm Notes and the Additional
Notes are hereinafter collectively referred to as the “Notes.” The Notes will be convertible into shares
of the Company’s common stock, par value $0.001 per share (the “Common Stock”) including any such
shares issuable upon conversion in connection with a “Make-Whole Fundamental Change” (as defined in the Offering Memorandum)
(the “Underlying Common Stock”), as set forth in the Offering Memorandum. This Agreement is to confirm
the agreement concerning the purchase of the Notes from the Company by the Initial Purchasers.


 


1.           Purchase and Resale of the Notes. The Notes will be offered and sold to the Initial Purchasers without registration
under the Securities Act of 1933, as amended (the “Securities Act”), in reliance on an exemption pursuant
to Section 4(a)(2) under the Securities Act. The Company has prepared a preliminary offering memorandum, dated November 20, 2019
(the “Preliminary Offering Memorandum”), a pricing term sheet substantially in the form attached hereto
as Schedule II (the “Pricing Term Sheet”) setting forth the terms of the Notes omitted from the Preliminary
Offering Memorandum and an offering memorandum, dated November 20, 2019 (the “Offering Memorandum”),
setting forth information regarding the Company and the Notes. The Preliminary Offering Memorandum, as supplemented and amended
as of the Applicable Time (as defined herein), together with the Pricing Term Sheet and any of the documents listed on Schedule
III(A) hereto are collectively referred to as the “Pricing Disclosure Package.” The Company hereby confirms
that it has authorized the use of the Pricing Disclosure Package and the Offering Memorandum in connection with the offering and
resale of the Notes by the Initial Purchasers. “Applicable Time” means 12:45 p.m. (New York City time)
on the date of this Agreement.


 






     

     


    

 


Any reference to the
Preliminary Offering Memorandum, the Pricing Disclosure Package or the Offering Memorandum shall be deemed to refer to and include
the Company’s most recent Annual Report on Form 10-K (the “Annual Report”) and all subsequent documents
filed (but not furnished) with the United States Securities and Exchange Commission (the “Commission”)
pursuant to Section 13(a), 13(c), 14 or 15(d) of the United States Securities Exchange Act of 1934, as amended (the “Exchange
Act”), on or prior to the date of the Preliminary Offering Memorandum, the Pricing Disclosure Package or the Offering
Memorandum, as the case may be. Any reference to the Preliminary Offering Memorandum, Pricing Disclosure Package or the Offering
Memorandum, as the case may be, as amended or supplemented, as of any specified date, shall be deemed to include any documents
filed with the Commission pursuant to Section 13(a), 13(c), 14 or 15(d) of the Exchange Act after the date of the Preliminary Offering
Memorandum, Pricing Disclosure Package or the Offering Memorandum, as the case may be, and prior to such specified date. All documents
filed under the Exchange Act and so deemed to be included in the Preliminary Offering Memorandum, Pricing Disclosure Package or
the Offering Memorandum, as the case may be, or any amendment or supplement thereto are hereinafter called the “Exchange
Act Reports.”


 


You have advised the
Company that you will offer and resell (the “Exempt Resales”) the Notes purchased by you hereunder on
the terms set forth in each of the Pricing Disclosure Package and the Offering Memorandum, as amended or supplemented, solely to
persons whom you reasonably believe to be “qualified institutional buyers” as defined in Rule 144A under the Securities
Act (“Rule 144A”) (each a “QIB”). Those persons specified above are referred
to herein as “Eligible Purchasers.”


 


2.             Representations, Warranties and Agreements of the Company. The Company represents, warrants and agrees as follows:


 


(a)               When
the Notes are issued and delivered pursuant to this Agreement, such Notes will not be of the same class (within the meaning of
Rule 144A) as securities of the Company that are listed on a national securities exchange registered under Section 6 of the Exchange
Act or that are quoted in a United States automated inter-dealer quotation system.


 


(b)             
Assuming the accuracy of your representations and warranties in Section 3(c) and the Initial Purchasers compliance with
their agreements set forth herein, the purchase of the Notes pursuant hereto and Exempt Resales are exempt from the registration
requirements of the Securities Act, it being understood that the Company makes no representation as to subsequent resales of the
Notes.


 






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(c)              
No form of general solicitation or general advertising within the meaning of Regulation D under the Securities Act (“Regulation
D”) (including, but not limited to, advertisements, articles, notices or other communications published in any newspaper,
magazine or similar medium or broadcast over television or radio, or any seminar or meeting whose attendees have been invited by
any general solicitation or general advertising) was used by the Company, any of its controlled affiliates or any of its representatives
(other than you, as to whom the Company makes no representation) in connection with the offer and sale of the Notes.


 


(d)               Each
of the Preliminary Offering Memorandum, the Pricing Disclosure Package and the Offering Memorandum, each as of its respective
date, contains all the information specified in, and meeting the requirements of, Rule 144A(d)(4) under the Securities Act in
all material respects.


 


(e)                Neither the Company nor any other person directed by the Company has sold or issued any securities that would be
integrated with the offering of the Notes contemplated by this Agreement pursuant to the Securities Act, the rules and
regulations thereunder or the interpretations thereof by the Commission in any manner that would require registration of the
Notes under the Securities Act.


 


(f)                The
Preliminary Offering Memorandum, the Pricing Disclosure Package and the Offering Memorandum have been prepared by the Company
for use by the Initial Purchasers in connection with the Exempt Resales. No order or decree preventing or suspending the use of
the Preliminary Offering Memorandum, the Pricing Disclosure Package or the Offering Memorandum, or any order asserting that the
transactions contemplated by this Agreement are subject to the registration requirements of the Securities Act has been issued,
and no proceeding for that purpose has commenced or is pending or, to the knowledge of the Company, is contemplated.


 


(g)               The Offering Memorandum will not, as of its date or as of the Closing Date, contain any untrue statement of a material fact
or omit to state a material fact necessary in order to make the statements therein, in the light of the circumstances under which
they were made, not misleading; provided that no representation or warranty is made as to information contained in or omitted
from the Offering Memorandum in reliance upon and in conformity with written information furnished to the Company through the Representative
by or on behalf of any Initial Purchaser specifically for inclusion therein, which information is specified in Section 8(e).


 


(h)               The
Pricing Disclosure Package did not, as of the Applicable Time, contain any untrue statement of a material fact or omit to state
a material fact necessary in order to make the statements therein, in the light of the circumstances under which they were made,
not misleading; provided that no representation or warranty is made as to information contained in or omitted from the
Pricing Disclosure Package made in reliance upon and in conformity with written information furnished to the Company through the
Representative by or on behalf of any Initial Purchasers specifically for inclusion therein, which information is specified in
Section 8(e).


 






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(i)                The
Company has not made any offer to sell or solicitation of an offer to buy the Notes that would constitute a “free writing
prospectus” (if the offering of the Notes was made pursuant to a registered offering under the Securities Act), as defined
in Rule 405 under the Securities Act (a “Free Writing Offering Document”) without the prior consent
of the Representative; any such Free Writing Offering Document the use of which has been previously consented to by the Initial
Purchasers is listed on Schedule III.


 


(j)                Each
Free Writing Offering Document listed in Schedule III(B) hereto, when taken together with the Pricing Disclosure Package, did
not, as of the Applicable Time, contain any untrue statement of a material fact or omit to state a material fact necessary to
make the statements therein, in the light of the circumstances under which they were made, not misleading; provided that
no representation or warranty is made as to information contained in or omitted from the Pricing Disclosure Package (or such Free
Writing Offering Document listed in Schedule III(B) hereto) in reliance upon and in conformity with written information furnished
to the Company through the Representative by or on behalf of any Initial Purchaser specifically for inclusion therein, which information
is specified in Section 8(e).


 


(k)               The
Exchange Act Reports, when they were or are filed with the Commission, conformed or will conform in all material respects to the
applicable requirements of the Exchange Act and the applicable rules and regulations of the Commission thereunder. The Exchange
Act Reports did not and will not, when filed with the Commission, contain an untrue statement of material fact or omit to state
a material fact necessary in order to make the statements therein, in the light of the circumstances under which they were made,
not misleading.


 


(l)                The
Company has been duly incorporated and is validly existing as a corporation in good standing under the laws of the State of Delaware,
with corporate power and authority to own or lease its properties and conduct its business as described in the Pricing Disclosure
Package and the Offering Memorandum. The subsidiaries listed in Exhibit 21.1 to Item 15 of the Annual Report on Form 10-K filed
with the Commission on March 18, 2019 and the subsidiaries listed in Schedule V hereto are the only subsidiaries of the Company
(collectively, the “Subsidiaries”). Each of the Subsidiaries has been duly organized and is validly
existing as a corporation, limited liability company or similar entity in good standing (to the extent that the concept of “good
standing” exists in a specified jurisdiction) under the laws of its jurisdiction of organization, with requisite power and
authority to own or lease its properties and conduct its business as described in the Pricing Disclosure Package and Offering
Memorandum. The Company and each of the Subsidiaries are duly qualified to transact business in all jurisdictions in which the
conduct of their business requires such qualification, except where the failure to be so qualified would not either (i) have,
individually or in the aggregate, a material adverse effect on the earnings, business, management, properties, assets, rights,
operations, condition (financial or otherwise), or prospects of the Company and the Subsidiaries, taken as a whole, or (ii) prevent
the consummation of the transactions contemplated hereby (the occurrence of any such effect or any such prevention described in
the foregoing clauses (i) and (ii) being referred to as a “Material Adverse Effect”).


 






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(m)              The
Company has an authorized capitalization as set forth in in the section of each of the Pricing Disclosure Package and the
Offering Memorandum titled “Description of Capital Stock”, and all of the issued shares of capital stock of the
Company have been duly authorized and validly issued and are fully paid and non-assessable. The outstanding shares of capital
stock of each of the Subsidiaries have been duly authorized and validly issued, are fully paid and non-assessable and are
owned by the Company or another Subsidiary free and clear of all liens, encumbrances and equities and claims, except for such
liens, encumbrances, equities or claims as could not, in the aggregate, reasonably be expected to have a Material Adverse
Effect.


 


(n)              
The Company has all requisite corporate power and authority, to execute, deliver and perform its obligations under the Indenture.
The Indenture has been duly and validly authorized by the Company, and upon its execution and delivery and, assuming due authorization,
execution and delivery by the Trustee, will constitute a valid and binding agreement of the Company, enforceable against the Company
in accordance with its terms, except as such enforceability may be limited by bankruptcy, fraudulent conveyance, insolvency, reorganization,
moratorium, and other laws relating to or affecting creditors’ rights generally and by general equitable principles (regardless
of whether such enforceability is considered in a proceeding in equity or at law). The Indenture will conform to the description
thereof in each of the Pricing Disclosure Package and the Offering Memorandum.


 


(o)               The
Company has all requisite corporate power and authority to execute, issue, sell and perform its obligations under the Notes. The
Notes have been duly authorized by the Company and, when duly executed by the Company in accordance with the terms of the Indenture,
assuming due authentication of the Notes by the Trustee, upon delivery to the Initial Purchasers against payment therefor in accordance
with the terms hereof, will be validly issued and delivered and will constitute valid and binding obligations of the Company entitled
to the benefits of the Indenture, enforceable against the Company in accordance with their terms, except as such enforceability
may be limited by bankruptcy, fraudulent conveyance, insolvency, reorganization, moratorium, and other laws relating to or affecting
creditors’ rights generally and by general equitable principles (regardless of whether such enforceability is considered
in a proceeding in equity or at law). The Notes will conform in all material respects to the description thereof in each of the
Pricing Disclosure Package and the Offering Memorandum.


 


(p)              
The Company has all requisite corporate power and authority to issue the Underlying Common Stock issuable upon conversion
of the Notes. The Underlying Common Stock has been duly and validly authorized by the Company and, when issued upon conversion
of the Notes in accordance with the terms of the Notes, will be validly issued, fully paid and non-assessable, and the issuance
of the Underlying Common Stock will not be subject to any preemptive or similar rights. The Underlying Common Stock will conform
in all material respects to the description thereof in each of the Pricing Disclosure Package and the Offering Memorandum.


 


(q)               The Company has all requisite corporate power and authority to execute, deliver, and perform its obligations under
this Agreement. The execution and delivery of, and the performance by the Company of its obligations under, this Agreement
has been duly and validly authorized by all necessary corporate action on the part of the Company, and this Agreement has
been duly executed and delivered by the Company.


 






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(r)               
Neither the Company nor any of the Subsidiaries is or, with the giving of notice or lapse of time or both, would currently
be (i) in violation of its certificate or articles of incorporation, by-laws, certificate of formation, limited liability agreement,
partnership agreement or other organizational documents, as applicable, or (ii) in violation of or in default under any agreement,
lease, contract, indenture or other instrument or obligation to which it is a party or by which it, or any of its properties, is
bound other than as disclosed in the Pricing Disclosure Package and the Offering Memorandum, including documents incorporated by
reference therein, and, solely with respect to this clause (ii), which violation or default would have a Material Adverse Effect.
The issuance and sale of the Notes by the Company and the issuance of the Underlying Common Stock upon conversion of the Notes,
the execution, delivery and performance by the Company of the Notes, the Indenture, and this Agreement, the application of the
proceeds from the sale of the Notes as described under “Use of Proceeds” in each of the Pricing Disclosure Package
and the Offering Memorandum and the consummation of the transactions contemplated hereby and thereby, do not and will not conflict
with or result in a breach of any of the terms or provisions of, or constitute a default under, any indenture, mortgage, deed of
trust or other agreement or instrument to which the Company or any Subsidiary is a party or by which the Company or any Subsidiary
or any of their respective properties is bound except as would not, individually or in the aggregate, have a Material Adverse Effect,
or of the certificate or articles of incorporation or by-laws of the Company or any law, order, rule or regulation judgment, order,
writ or decree applicable to the Company or any Subsidiary of any court or of any government, regulatory body or administrative
agency or other governmental body having jurisdiction.


 


(s)              
Each approval, consent, order, authorization, designation, declaration or filing by or with any regulatory, administrative
or other governmental body necessary for the issuance and sale of the Notes by the Company and the issuance of the Underlying Common
Stock upon conversion of the Notes, the execution, delivery and performance by the Company of the Notes, the Indenture and this
Agreement, the application of the proceeds from the sale of the Notes as described under “Use of Proceeds” in each
of the Pricing Disclosure Package and the Offering Memorandum and the consummation of the transactions contemplated hereby and
thereby (except such additional steps as may be required by the Commission or Financial Industry Regulatory Authority, Inc. (“FINRA”)
or such additional steps as may be necessary to qualify the Shares for public offering by the Underwriters under state securities
or Blue Sky laws) has been obtained or made and is in full force and effect.


 


(t)                The consolidated financial statements of the Company and the Subsidiaries, together with related notes and schedules as
set forth or incorporated by reference in the Pricing Disclosure Package and the Offering Memorandum, present fairly in all material
respects the financial position and the results of operations and cash flows of the Company and the consolidated Subsidiaries,
at the indicated dates and for the indicated periods. Such financial statements and related schedules have been prepared in accordance
with U.S. generally accepted accounting principles (“GAAP”), consistently applied throughout the periods
involved, except as disclosed therein, and all adjustments necessary for a fair presentation of results for such periods have been
made. The summary consolidated financial and statistical data included or incorporated by reference in the Pricing Disclosure Package
and the Offering Memorandum present fairly the information shown therein and such data has been compiled on a basis consistent
with the financial statements presented therein and the books and records of the Company. The Company and the Subsidiaries do not
have any material liabilities or obligations, direct or contingent (including any off-balance sheet obligations or any “variable
interest entities” within the meaning of Financial Accounting Standards Board Interpretation No. 46), not disclosed
in the Pricing Disclosure Package and the Offering Memorandum. There are no financial statements (historical or pro forma) that
are required to be included in the Pricing Disclosure Package or the Offering Memorandum that are not included as required. The
interactive data in eXtensible Business Reporting Language included or incorporated by reference in the Pricing Disclosure Package
and the Offering Memorandum fairly present the information called for in all material respects and have been prepared in accordance
with the Commission’s rules and guidelines applicable thereto.


 






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(u)               PricewaterhouseCoopers
LLP, who have certified certain of the financial statements filed with the Commission as part of, or incorporated by reference
in, the Pricing Disclosure Package and the Offering Memorandum, is an independent registered public accounting firm with respect
to the Company and the Subsidiaries within the meaning of the Securities Act and the applicable Rules and Regulations and the
Public Company Accounting Oversight Board (United States) (the “PCAOB”).


 


(v)               The
Company maintains a system of internal control over financial reporting (as such term is defined in Rule 13a-15(f) of the Exchange
Act) that complies with the requirements of the Exchange Act and that has been designed by, or under the supervision of, the Company’s
principal executive and principal financial officers, to provide reasonable assurance regarding the reliability of financial reporting
and the preparation of financial statements for external purposes in accordance with GAAP. The Company maintains accounting controls
sufficient to provide reasonable assurance that (i) transactions are executed in accordance with management’s general or
specific authorization, (ii) transactions are recorded as necessary to permit preparation of the Company’s financial statements
in conformity with GAAP and to maintain accountability for its assets, (iii) access to the Company’s assets is permitted
only in accordance with management’s general or specific authorization, (iv) the recorded accountability for the Company’s
assets is compared with existing assets at reasonable intervals and appropriate action is taken with respect to any differences,
and (v) the interactive data in eXtensible Business Reporting Language included or incorporated by reference in the Pricing Disclosure
Package and the Offering Memorandum fairly present the information called for in all material respects and are prepared in accordance
in all material respects with the Commission’s rules and guidelines applicable thereto. As of the date of the most recent
balance sheet of the Company and its consolidated subsidiaries reviewed or audited by PricewaterhouseCoopers LLP and reviewed
by the audit committee of the board of directors of the Company (the “Audit Committee”), there were
no material weaknesses in the Company’s internal controls.


 


(w)             
The Company has established and maintains “disclosure controls and procedures” (as defined in Rules 13a-14(c)
and 15d-14(c) under the Exchange Act); the Company’s “disclosure controls and procedures” are reasonably designed
to ensure that all information (both financial and non-financial) required to be disclosed by the Company in the reports that it
files or submits under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the
rules and regulations of the Exchange Act, and that all such information is accumulated and communicated to the Company’s
management as appropriate to allow timely decisions regarding required disclosure and to make the certifications of the Chief Executive
Officer and Chief Financial Officer of the Company required under the Exchange Act with respect to such reports.


 






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(x)               The
Company is in compliance in all material respects with all applicable provisions of the Sarbanes-Oxley Act of 2002, as amended,
and all rules and regulations promulgated thereunder or supplementing the provisions thereof that are in effect.


 


(y)              
Since the respective dates of which information is given in the Pricing Disclosure Package and the Offering Memorandum,
as each may be amended or supplemented, there has not been any material adverse change or any development involving a prospective
material adverse change in or affecting the earnings, business, management, properties, assets, rights, operations, condition (financial
or otherwise), or prospects of the Company and the Subsidiaries taken as a whole, whether or not occurring in the ordinary course
of business, and there has not been any material transaction entered into or any material transaction that is probable of being
entered into by the Company or the Subsidiaries, other than transactions in the ordinary course of business and changes and transactions
described in the Pricing Disclosure Package and the Offering Memorandum, as each may be amended or supplemented. The Company and
the Subsidiaries have no material contingent obligations which are not disclosed in the Company’s financial statements which
are included in the Pricing Disclosure Package and the Offering Memorandum.


 


(z)                Neither
the Company nor any of the Subsidiaries own any real property. The Company and the Subsidiaries have good title to all of the
material properties and assets reflected in the consolidated financial statements hereinabove described or described in the
Pricing Disclosure Package and the Offering Memorandum, subject to no lien, mortgage, pledge, charge or encumbrance of any
kind except those reflected in such financial statements or described in the Pricing Disclosure Package and the
Offering Memorandum or which are not material in amount. The Company and the Subsidiaries occupy their leased properties
under valid and binding leases conforming in all material respects to the description thereof set forth in the Pricing
Disclosure Package and the Offering Memorandum.


 


(aa)       
      The Company and each of the Subsidiaries hold all licenses, certificates and permits (collectively,
 “Governmental Licenses”) from governmental authorities which are necessary to the conduct of their respective
businesses, except where the failure to hold such licenses, certificates and permits would not have a Material Adverse Effect.
The Company and the Subsidiaries are in compliance with the terms and conditions of all Governmental Licenses, and all of the
Governmental Licenses are valid and in full force and effect, except where the failure to be in such compliance would not have
a Material Adverse Effect. Neither the Company nor any of the Subsidiaries has received any written notice of proceedings relating
to the revocation or modification of any Governmental License.


 


(bb)             Except
as described in the Pricing Disclosure Package and the Offering Memorandum, the Company and the Subsidiaries each own, possess,
have rights to, or can acquire on reasonable terms all material patents, patent rights, trademarks, trade names, service marks,
service names, copyrights, license rights, know-how (including trade secrets and other unpatented and unpatentable proprietary
or confidential information, systems or procedures) and other intellectual property rights (“Intellectual Property”)
necessary to carry on their respective business, except where the failure to own or possess or inability to acquire on reasonable
terms any such Intellectual Property would not have a Material Adverse Effect. There are no outstanding options, licenses or agreements
of any kind relating to the Intellectual Property of the Company that are required to be described in the Pricing Disclosure Package
and the Offering Memorandum and that are not described in all material respects. None of the technology employed by the Company
or any of the Subsidiaries has been obtained or is being used by the Company in violation of any contractual obligation binding
on the Company, any of the Subsidiaries or, to the knowledge of the Company, any of the officers, directors or employees of the
Company or any of the Subsidiaries, other than such violations as would not individually or in the aggregate if the subject of
an unfavorable decision, ruling or finding, have a Material Adverse Effect. To the Company’s knowledge, neither the Company
nor the Subsidiaries has infringed or violated the valid and enforceable Intellectual Property of any other person that would,
individually or in the aggregate, have a Material Adverse Effect. Except as described in the Pricing Disclosure Package and the
Offering Memorandum, neither the Company nor any of the Subsidiaries has received any written or oral notice or communications
alleging that the Company or any of the Subsidiaries has violated, infringed or conflicted with, or by conducting its business
as set forth in the Pricing Disclosure Package and the Offering Memorandum, would violate, infringe or conflict with, any of the
Intellectual Property of any other person or entity, other than such violations, infringements or conflicts which, individually
or in the aggregate if the subject of an unfavorable decision, ruling or finding, would not have a Material Adverse Effect. The
Company knows of no infringement by others of Intellectual Property owned by or licensed to the Company or any of the Subsidiaries,
which would have a Material Adverse Effect.


 






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(cc)            
There is no action, suit, claim or proceeding pending or, to the knowledge of the Company, threatened against the Company
or any of the Subsidiaries before any court or administrative agency or otherwise which if determined adversely to the Company
or any of the Subsidiaries would have a Material Adverse Effect, except as set forth in the Pricing Disclosure Package and the
Offering Memorandum.


 


(dd)           
Neither the Company nor any of the Subsidiaries is in violation of any statute, rule, regulation, decision or order of any
governmental agency or body or any court, domestic or foreign, relating to the use, disposal or release of hazardous or toxic substances
or relating to the protection or restoration of the environment or human exposure to hazardous or toxic substances (collectively,
 “environmental laws”), owns or operates any real property that is, to the knowledge of the Company, contaminated with
any substance that is subject to environmental laws, is liable for any off-site disposal or contamination pursuant to any environmental
laws, or is subject to any claim relating to any environmental laws, which violation, contamination, liability or claim would,
individually or in the aggregate, have a Material Adverse Effect; and the Company is not aware of any pending investigation which
might lead to such a claim.


 


(ee)            
The Company and the Subsidiaries have filed all federal, state, local and foreign tax returns (or timely filed applicable
extensions therefor) which have been required to be filed and have paid all taxes indicated by such returns and all assessments
received by them to the extent that such taxes have become due, except for such taxes as are being contested in good faith and
for which an adequate reserve or accrual has been established in accordance with GAAP or which would not, singularly or in the
aggregate, have a Material Adverse Effect. The accruals and reserves on the books and records of the Company and the Subsidiaries
in respect of tax liabilities for any taxable period are adequate to meet any assessments and related liabilities for any such
period, and the Company has no knowledge of any actual or proposed additional material tax assessments with respect to the Company
or its Subsidiaries for any such period. Since December 31, 2018, the Company and the Subsidiaries have not incurred any liability
for taxes other than in the ordinary course of business.


 






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(ff)             
The Company, after giving effect to the offering and sale of the Notes contemplated hereunder and the application of the
net proceeds from such sale as described under “Use of Proceeds” in each of the Pricing Disclosure Package and the
Offering Memorandum, will not be required to register as an “investment company” within the meaning of such term under
the Investment Company Act of 1940, as amended, and the rules and regulations of the Commission thereunder.


 


(gg)            
Neither the Company, nor to the Company’s knowledge, any of its affiliates, has taken or may take, directly or indirectly,
any action designed to cause or result in, or which has constituted or which might reasonably be expected to constitute, the stabilization
or manipulation of the price of any security of the Company in connection with the offering of the Notes in violation of Regulation
M.


 


(hh)           
Neither the Company nor any of the Subsidiaries nor any director or officer of the Company, nor, to the knowledge of the
Company, any agent, employee or affiliate of the Company or any of the Subsidiaries, in each case, acting on behalf of the Company,
has in the course of its actions for, or on behalf of, the Company or any of the Subsidiaries: (i) made any unlawful contribution,
gift or other unlawful expense relating to political activity; (ii) made any direct or indirect bribe, kickback, rebate, payoff,
influence payment, or otherwise unlawfully provided anything of value, to any “foreign official” (as defined in the
U.S. Foreign Corrupt Practices Act of 1977, as amended (collectively, the “FCPA”)) or domestic government
official; or (iii) violated or is in violation of any provision of the FCPA, the Bribery Act 2010 of the United Kingdom, as amended
(the “Bribery Act 2010”), or any other applicable anti-corruption or anti-bribery statute or regulation.
The Company and the Subsidiaries and, to the knowledge of the Company, the Company’s affiliates, have conducted their respective
businesses in compliance with the FCPA, Bribery Act 2010, and all other applicable anti-corruption and anti-bribery statutes and
regulations, and have instituted and maintain policies and procedures designed to ensure, and which are reasonably expected to
ensure, continued compliance therewith.


 


(ii)               The
operations of the Company and its Subsidiaries are and have been conducted at all times in compliance with applicable financial
record keeping and reporting requirements of the Currency and Foreign Transactions Reporting Act of 1970, as amended, the money
laundering statutes of all jurisdictions, the rules and regulations thereunder and any related or similar rules, regulations or
guidelines, that have been issued, administered or enforced by any governmental agency (collectively, the “Money Laundering
Laws”) and no action, suit or proceeding by or before any court or governmental agency, authority or body or any
arbitrator or non-governmental authority involving the Company or any of its subsidiaries with respect to the Money Laundering
Laws is pending or, to the knowledge of the Company, threatened


 






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(jj)              
Neither the Company nor any Subsidiaries, nor any of their directors, officers or employees, nor, to the Company’s
knowledge, any agent, affiliate or representative of the Company or any Subsidiary, is an individual or entity that is, or is owned
or controlled by an individual or entity that is:


 


		(i)	the subject of any sanctions administered or enforced by the U.S. Department of Treasury’s
Office of Foreign Assets Control, the United Nations Security Council, the European Union, Her Majesty’s Treasury, or other
relevant sanctions authority (collectively, “Sanctions”), nor



 


		(ii)	located, organized or resident in a country or territory that is the subject of Sanctions (including,
without limitation, Cuba, Iran, North Korea and Syria).



 


		(iii)	Neither the Company nor any Subsidiary will, directly or indirectly, use the proceeds of the offering,
or lend, contribute or otherwise make available such proceeds to any subsidiary, joint venture partner or other individual or entity:



 


		(A)	to fund or facilitate any activities or business of or with any individual or entity or in any
country or territory that, at the time of such funding or facilitation, is the subject of Sanctions; or



 


		(B)	in any other manner that will result in a violation of Sanctions by any individual or entity (including
any individual or entity participating in the offering, whether as underwriter, advisor, investor or otherwise).



 


		(iv)	For the past five years, neither the Company nor any Subsidiary has knowingly engaged in, and is
not now knowingly engaged in, any dealings or transactions with any individual or entity, or in any country or territory, that
at the time of the dealing or transaction is or was the subject of Sanctions.



 


(kk)              No material labor dispute with the employees of the Company or any of the Subsidiaries exists,
except as described in the Pricing Disclosure Package and the Offering Memorandum, or, to the knowledge of the Company, is
imminent; and the Company is not aware of any existing, threatened or imminent labor disturbance by the employees of any of
its principal suppliers, manufacturers or contractors that would be reasonably likely to have a Material Adverse Effect.


 


(ll)              
None of the transactions contemplated by this Agreement (including, without limitation, the use of the proceeds from the
sale of the Notes), will violate or result in a violation of Section 7 of the Exchange Act, or any regulation promulgated thereunder,
including, without limitation, Regulations T, U and X of the Board of Governors of the Federal Reserve System.


 


(mm)           The Company and each of the Subsidiaries carry, or are covered by, insurance in such amounts and
covering such risks as is in the Company’s reasonable judgement adequate for the conduct of their respective businesses
and the value of their respective properties and as is customary for companies engaged in similar businesses.


 






    	 	11	 



     


    

 


(nn)            The
Company and each Subsidiary is in compliance in all material respects with all presently applicable provisions of the Employee
Retirement Income Security Act of 1974, as amended, including the regulations and published interpretations thereunder (“ERISA”);
no “reportable event” (as defined in ERISA) has occurred with respect to any “pension plan” (as defined
in ERISA) for which the Company and each Subsidiary would have any material liability; the Company and each Subsidiary has not
incurred and does not expect to incur liability under (i) Title IV of ERISA with respect to termination of, or withdrawal from,
any “pension plan” or (ii) Sections 412 or 4971 of the Internal Revenue Code of 1986, as amended, including the regulations
and published interpretations thereunder (the “Code”); and each “pension plan” for which
the Company or any Subsidiary would have any liability that is intended to be qualified under Section 401(a) of the Code is so
qualified in all material respects and nothing has occurred, whether by action or by failure to act, which would cause the loss
of such qualification.


 


(oo)             Except as described in the Pricing Disclosure Package and the Offering Memorandum or as described in the Company’s
Loan and Security Agreement with Silicon Valley Bank effective August 2, 2018, as amended, no Subsidiary of the Company is currently
prohibited, directly or indirectly, from paying any dividends to the Company, from making any other distribution on such Subsidiary’s
capital stock, from repaying to the Company any loans or advances to such Subsidiary from the Company or from transferring any
of such Subsidiary’s property or assets to the Company or any other Subsidiary of the Company.


 


(pp)           
The statistical and market-related data included or incorporated by reference in the Pricing Disclosure Package and the
Offering Memorandum are based on or derived from sources that the Company in good faith believes to be reliable in all material
respects.


 


(qq)             Except as described in the Pricing Disclosure Package, there are no contracts, agreements or understandings between the
Company and any person granting such person the right to require the Company to file a registration statement under the Securities
Act with respect to any securities of the Company owned or to be owned by such person or in any securities being registered pursuant
to any other registration statement filed by the Company under the Securities Act.


 


(rr)               Neither
the Company nor any of the Subsidiaries is a party to any contract, agreement or understanding with any person (other than this
Agreement) that would give rise to a valid claim against any of them or any Initial Purchaser for a brokerage commission, finder’s
fee or like payment in connection with the offering and sale of the Notes.


 


(ss)            
The statements set forth in each of the Pricing Disclosure Package and the Offering Memorandum under the caption “Description
of Notes,” insofar as they purport to constitute a summary of the terms of the Notes, under the caption “Description
of Capital Stock,” insofar as they purport to constitute a summary of the Underlying Common Stock and under the caption “Certain
U.S. Federal Income Tax Considerations,” insofar as they purport to summarize the provisions of the laws and documents referred
to therein, are accurate summaries in all material respects.


 






    	 	12	 



     


    

 


(tt)             
The Company is not a “shell company” as described in Rule 144(i) under the Securities Act.


 


(uu)             Except
as would not, individually or in the aggregate, have a Material Adverse Effect, the Company and each Subsidiary’s information
technology assets and equipment, computers, systems, networks, hardware, software, websites, applications, and databases (collectively,
 “IT Systems”) are adequate for, and operate and perform in all material respects as required in connection
with the operation of the business of the Company and its Subsidiaries as currently conducted, free and clear of all material
bugs, errors, defects, Trojan horses, time bombs, malware and other corruptants. The Company and all Subsidiaries have implemented
and maintained commercially reasonable controls, policies, procedures, and safeguards to maintain and protect their material confidential
information and the integrity, continuous operation, redundancy and security of all IT Systems and data (including all personal,
personally identifiable, sensitive, confidential or regulated data (“Personal Data”)) used in connection
with their businesses, and except as described in the Pricing Disclosure Package, there have been no breaches, violations, outages
or unauthorized uses of or accesses to same, except for those that have been remedied without material cost or liability or the
duty to notify any other person, nor any incidents under internal review or investigations relating to the same. The Company and
its Subsidiaries are presently in compliance with all applicable laws or statutes and all judgments, orders, rules and regulations
of any court or arbitrator or governmental or regulatory authority, internal policies and contractual obligations relating to
the privacy and security of IT Systems and Personal Data and to the protection of such IT Systems and Personal Data from unauthorized
use, access, misappropriation or modification, except, in each case, as would not, individually or in the aggregate, have a Material
Adverse Effect.


 


(vv)           
No forward looking statement (within the meaning of Section 27A of the Securities Act and Section 21E of the Exchange Act)
included or incorporated by reference in any of the Pricing Disclosure Package or the Offering Memorandum has been made or reaffirmed
without a reasonable basis or has been disclosed other than in good faith.


 






    	 	13	 



     


    

 


(ww)           Except as described in the Pricing Disclosure Package and the Offering Memorandum, and except as would
not, singly or in the aggregate, have a Material Adverse Effect: (i) neither the Company nor any of the Subsidiaries has
received any unresolved FDA Form 483, notice of adverse filing, warning letter, untitled letter or other correspondence or
notice from the U.S. Food and Drug Administration (“FDA”), or any other court or arbitrator or
federal, state, local or foreign governmental or regulatory authority, alleging or asserting noncompliance with the Federal
Food, Drug and Cosmetic Act (21 U.S.C. § 301 et seq.) (the “FFDCA”); (ii) the Company and
each of the Subsidiaries is and has been in compliance with applicable health care laws, including without limitation, the
FFDCA, the federal Anti-Kickback Statute (42 U.S.C. § 1320a-7b(b)), the civil False Claims Act (31 U.S.C. §§
3729 et seq.), the administrative False Claims Law (42 U.S.C. § 1320a-7b(a)), the Stark law (42 U.S.C. Section 1395nn),
the Health Insurance Portability and Accountability Act of 1996 (42 U.S.C. Section 1320d et seq.) as amended by the Health
Information Technology for Economic and Clinical Health Act (42 U.S.C. Section 17921 et seq.), the exclusion laws (42 U.S.C.
Section 1320a-7),the Anti-Inducement Law (42 U.S.C. §1320a-7a(a)(5)), the exclusion laws, Social Security Act §
1128 (42 U.S.C. § 1320a-7), Medicare (Title XVIII of the Social Security Act), Medicaid (Title XIX of the Social
Security Act), and the Patient Protection and Affordable Care Act of 2010 (Public Law 111-148), as amended by the Health Care
and Education Affordability Reconciliation Act of 2010 (Public Law 111-152), and the regulations promulgated pursuant to such
laws, and comparable state laws, and all other local, state, federal, national, supranational and foreign laws, manual
provisions, policies and administrative guidance relating to the regulation of the Company (collectively, “Health
Care Laws”); (iii) the Company and each of the Subsidiaries possesses all licenses,
certificates, approvals, clearances, authorizations, permits and supplements or amendments thereto required by any such
Health Care Laws and/or to carry on its businesses as now or proposed to be conducted
(“Authorizations”) and such Authorizations are valid and in full force and effect and the Company
is not in violation of any term of any such Authorizations; (iv) neither the Company nor any of the Subsidiaries has
received notice of any ongoing claim, action, suit, proceeding, hearing, enforcement, investigation, arbitration or other
action from any U.S. or non-U.S. federal, state, local or other governmental or regulatory authority, governmental or
regulatory agency or body, court, arbitrator or self-regulatory organization (each, a
 “Governmental Authority”) or third party alleging that any product operation or activity is in
violation of any Health Care Laws or Authorizations or has any knowledge that any such Governmental Authority or third party
is considering any such claim, litigation, arbitration, action, suit, investigation or proceeding; (v) neither the
Company nor any of the Subsidiaries has received notice that any Governmental Authority has taken, is taking or intends to
take action to limit, suspend, modify or revoke any Authorizations or has any knowledge that any such Governmental Authority
is considering such action; (vi) the Company and each of the Subsidiaries has filed, obtained, maintained or submitted
all reports, documents, forms, notices, applications, records, claims, submissions and supplements or amendments as required
by any Health Care Laws or Authorizations and that all such reports, documents, forms, notices, applications, records,
claims, submissions and supplements or amendments were complete, correct and not misleading on the date filed (or were
corrected or supplemented by a subsequent submission); and (vii) neither the Company nor any of the Subsidiaries has,
either voluntarily or involuntarily, initiated, conducted, or issued or caused to be initiated, conducted or issued, any
recall, market withdrawal or replacement, safety alert, post sale warning, “dear doctor” letter, or other notice
or action relating to the alleged lack of safety or efficacy of any product or any alleged product defect or violation
and, to the Company’s knowledge, no third party has initiated or conducted any such notice or action.


 






    	 	14	 



     


    

 


(xx)              To
the knowledge of the Company, the research, studies and tests conducted by or on behalf of the Company and the Subsidiaries have
been and, if still pending, are being conducted with reasonable care and in accordance with experimental protocols, procedures
and controls pursuant to all Health Care Laws and Authorizations; the descriptions of the results of such research, studies and
tests contained in the Pricing Disclosure Package and the Offering Memorandum are accurate and complete and fairly present the
data derived from such research, studies and tests; except to the extent disclosed in the Pricing Disclosure Package and the Offering
Memorandum, the Company is not aware of any research, studies or tests, the results of which the Company believes reasonably call
into question the research, study or test results described or referred to in the Pricing Disclosure Package and the Offering
Memorandum when viewed in the context in which such results are described; and neither the Company nor any of the Subsidiaries
has received any notices or correspondence from any Governmental Authority requiring the termination, suspension or material modification
of any research, study or test conducted by or on behalf of the Company or the Subsidiaries, as applicable. To the knowledge of
the Company, there have been no adverse episodes or complications resulting from any research, study or test conducted by or on
behalf of the Company or the Subsidiaries.


 


Any certificate signed
by any officer of the Company and delivered to the Representative or counsel for the Initial Purchasers in connection with the
offering of the Notes shall be deemed to be a representation and warranty by the Company, as to matters covered thereby, to each
Initial Purchaser.


 


3.           Purchase of the Notes by the Initial Purchasers, Agreements to Sell, Purchase and Resell.


 


(a)              
The Company hereby agrees, on the basis of the representations, warranties, covenants and agreements of the Initial Purchasers
contained herein and subject to all the terms and conditions set forth herein, to issue and sell to the Initial Purchasers and,
upon the basis of the representations, warranties and agreements of the Company herein contained and subject to all the terms and
conditions set forth herein, each Initial Purchaser agrees, severally and not jointly, to purchase from the Company, at a purchase
price of 97% of the principal amount thereof, plus accrued interest from the Closing Date to the date of payment, if any, the principal
amount of Firm Notes set forth opposite the name of such Initial Purchaser in Schedule I hereto. The Company shall not be obligated
to deliver any of the securities to be delivered hereunder except upon payment for all of the securities to be purchased as provided
herein.


 


(b)              
In addition, the Company hereby agrees, on the basis of the representations and warranties, covenants and agreements of
the Initial Purchasers contained herein and subject to all the terms and conditions set forth herein, to issue and sell to the
Initial Purchasers the Additional Notes, and the Initial Purchasers shall have the right to purchase, severally and not jointly,
up to $5,000,000 aggregate principal amount of Additional Notes at a purchase price referred to in the preceding paragraph, plus
accrued and unpaid interest from the Closing Date to the date of payment, if any, solely for the purpose of covering sales of Notes
in excess of the principal amount of the Firm Notes. The Representative may exercise this right on behalf of the Initial Purchasers
in whole or from time to time in part by giving written notice not later than 13 days after the date of this Agreement. Any exercise
notice shall specify the principal amount of Additional Notes to be purchased by the Initial Purchasers and the date on which such
Additional Notes are to be purchased. Unless otherwise agreed to by the Company, each purchase date must be at least one business
day after the written notice is given and may not be earlier than the closing date for the Firm Notes nor later than ten business
days after the date of such notice. On each day, if any, that Additional Notes are to be purchased (an “Option Closing
Date”), each Initial Purchaser agrees, severally and not jointly, to purchase the principal amount of Additional
Notes (subject to such adjustments to eliminate fractional Notes as you may determine) that bears the same proportion to the total
principal amount of Additional Notes to be purchased on such Option Closing Date as the principal amount of Firm Notes set forth
in Schedule I opposite the name of such Initial Purchaser bears to the total principal amount of Firm Notes.


 






    	 	15	 



     


    

 


(c)              
Each of the Initial Purchasers, severally and not jointly, hereby represents and warrants to the Company and agrees that
it will offer the Notes for sale upon the terms and conditions set forth in this Agreement and in the Pricing Disclosure Package.
Each of the Initial Purchasers, severally and not jointly, hereby represents and warrants to, and agrees with, the Company, on
the basis of the representations, warranties and agreements of the Company, that such Initial Purchaser: (i) is a QIB with such
knowledge and experience in financial and business matters as are necessary in order to evaluate the merits and risks of an investment
in the Notes; (ii) is purchasing the Notes pursuant to a private sale exempt from registration under the Securities Act; and (iii)
in connection with the Exempt Resales, will solicit offers to buy the Notes only from, and will offer to sell the Notes only to,
the Eligible Purchasers in accordance with this Agreement and on the terms contemplated by the Pricing Disclosure Package) in connection
with the offering of the Notes.


 


(d)              
The Initial Purchasers have not nor, prior to the later to occur of (A) the Closing Date and (B) completion of the distribution
of the Notes, will not, use, authorize use of, refer to or distribute any material in connection with the offering and sale of
the Notes other than (i) the Preliminary Offering Memorandum, the Pricing Disclosure Package, the Offering Memorandum, (ii) any
written communication that contains either (x) no “issuer information” (as defined in Rule 433(h)(2) under the Securities
Act) or (y) “issuer information” that was included (including through incorporation by reference) in the Preliminary
Offering Memorandum or any Free Writing Offering Document listed on Schedule III hereto, (iii) the Free Writing Offering Documents
listed on Schedule III hereto, (iv) any written communication prepared by such Initial Purchaser and approved by the Company in
writing, or (v) any written communication relating to or that contains the terms of the Notes and/or other information that was
included (including through incorporation by reference) in the Preliminary Offering Memorandum, the Pricing Disclosure Package
or the Offering Memorandum.


 


(e)              
Each of the Initial Purchasers hereby acknowledges that upon original issuance thereof, and until such time as the same
is no longer required under the applicable requirements of the Securities Act, the Notes (and all securities issued in exchange
therefore or in substitution thereof) shall bear legends substantially in the forms as set forth in the “Transfer Restrictions”
section of the Pricing Disclosure Package and Offering Memorandum (along with such other legends as the Company and its counsel
deem necessary).


 


Each of the Initial Purchasers
understands that the Company and, for purposes of the opinions to be delivered to the Initial Purchasers pursuant to Sections 7(c),
7(d), and 7(e) hereof, counsel to the Company and counsel to the Initial Purchasers, will rely upon the accuracy and truth of the
foregoing representations, warranties and agreements, and the Initial Purchasers hereby consent to such reliance.


 


4.          
Delivery of the Notes and Payment Therefor. Delivery to the Initial Purchasers of and payment for the Notes shall
be made at the office of Fenwick & West LLP, at 10:00 a.m., New York City time, on the Closing Date. The place of closing for
the Notes and the Closing Date may be varied by agreement between the Initial Purchasers and the Company.


 






    	 	16	 



     


    

 


Payment for any Additional
Notes shall be made to the Company against delivery of such Additional Notes for the respective accounts of the several Initial
Purchasers at 10:00 a.m., New York City time, on the Option Closing Date.


 


The Notes will be delivered
to the Initial Purchasers, or the Trustee as custodian for The Depository Trust Company (“DTC”), against
payment by or on behalf of the Initial Purchasers of the purchase price therefor by wire transfer in immediately available funds,
by causing DTC to credit the Notes to the account of the Initial Purchasers at DTC. The Notes will be evidenced by one or more
global securities in definitive form (the “Global Notes”) and will be registered in the name of Cede
 & Co. as nominee of DTC. The Notes to be delivered to the Initial Purchasers shall be made available to the Initial Purchasers
in New York City for inspection and packaging not later than 10:00 a.m., New York City time, on the business day next preceding
the Closing Date or the Option Closing Date, as the case may be.


 


5.            
Agreements of the Company. The Company agrees with each of the Initial Purchasers as follows:


 


(a)               The
Company will furnish to the Initial Purchasers, without charge, within one business day of the date of the Offering Memorandum,
such number of copies of the Offering Memorandum as may then be amended or supplemented as they may reasonably request.


 


(b)               The
Company will prepare the Offering Memorandum in a form approved by the Initial Purchasers and will not make any amendment or supplement
to the Pricing Disclosure Package or to the Offering Memorandum of which the Initial Purchasers shall not previously have been
advised or to which they shall reasonably object after being so advised.


 


(c)             
The Company consents to the use of the Pricing Disclosure Package and the Offering Memorandum in accordance with the securities
or Blue Sky laws of the jurisdictions in which the Notes are offered by the Initial Purchasers and by all dealers to whom Notes
may be sold, in connection with the offering and sale of the Notes.


 


(d)              
If, at any time prior to completion of the distribution of the Notes by the Initial Purchasers to Eligible Purchasers, any
event occurs or information becomes known that, in the judgment of the Company or in the opinion of counsel for the Initial Purchasers,
should be set forth in the Pricing Disclosure Package or the Offering Memorandum so that the Pricing Disclosure Package or the
Offering Memorandum, as then amended or supplemented, does not include any untrue statement of material fact or omit to state a
material fact necessary in order to make the statements therein, in the light of the circumstances under which they were made,
not misleading, or if it is necessary to supplement or amend the Pricing Disclosure Package or the Offering Memorandum in order
to comply with any law, the Company will forthwith prepare an appropriate supplement or amendment thereto, and will as promptly
as practicable furnish to the Initial Purchasers and dealers a reasonable number of copies thereof.


 






    	 	17	 



     


    

 


(e)              
 The Company will not make any offer to sell or solicitation of an offer to buy the Notes that would constitute a Free Writing
Offering Document without the prior consent of the Representative, which consent shall not be unreasonably withheld or delayed.
If at any time following issuance of a Free Writing Offering Document any event occurred or occurs as a result of which such Free
Writing Offering Document conflicts with the information in the Preliminary Offering Memorandum, the Pricing Disclosure Package
or the Offering Memorandum or, when taken together with the information in the Preliminary Offering Memorandum, the Pricing Disclosure
Package or the Offering Memorandum, includes an untrue statement of a material fact or omits to state any material fact necessary
in order to make the statements therein, in the light of the circumstances then prevailing, not misleading, as promptly as practicable
after becoming aware thereof, the Company will give notice thereof to the Initial Purchasers through the Representative and, if
requested by the Representative, will prepare and furnish without charge to each Initial Purchaser a Free Writing Offering Document
or other document which will correct such conflict, statement or omission.


 


(f)               Promptly
from time to time to take such action as the Initial Purchasers may reasonably request to qualify the Notes and the Underlying
Common Stock for offering and sale under the securities or Blue Sky laws of such jurisdictions as the Initial Purchasers may request
and to comply with such laws so as to permit the continuance of sales and dealings therein in such jurisdictions for as long as
may be necessary to complete the distribution of the Notes and the Underlying Common Stock; provided that in connection
therewith the Company shall not be required to (i) qualify as a foreign corporation in any jurisdiction in which it would not
otherwise be required to so qualify, (ii) file a general consent to service of process in any such jurisdiction, or (iii) subject
itself to taxation in any jurisdiction in which it would not otherwise be subject.


 


(g)              
For a period commencing on the date hereof and ending on the 75th day after the date of the Offering Memorandum, the Company
agrees not to, directly or indirectly, (i) offer for sale, sell, or otherwise dispose of (or enter into any transaction or device
that is designed to, or would be expected to, result in the disposition by any person at any time in the future of) any shares
of Common Stock or securities convertible into or exchangeable for shares of Common Stock, or sell or grant options, rights or
warrants with respect to any shares of Common Stock or securities convertible into or exchangeable for shares of Common Stock,
(ii) enter into any swap or other derivatives transaction that transfers to another, in whole or in part, any of the economic benefits
or risks of ownership of such shares of Common Stock, whether any such transaction described in clause (i) or (ii) above is to
be settled by delivery of Common Stock or other securities, in cash or otherwise, (iii) file, or cause to be filed a registration
statement, including any amendments, with respect to the registration of Common Stock or securities convertible, exercisable or
exchangeable into Common Stock (other than any registration statement on Form S-8), or (iv) publicly disclose the intention to
do any of the foregoing, in each case without the prior written consent of Barclays, on behalf of the Initial Purchasers, and to
cause each officer and director of the Company set forth on Schedule IV hereto to furnish to the Representative, prior to the date
of this Agreement, a letter or letters, substantially in the form of Exhibit A hereto (the “Lock-Up Agreements”).
Notwithstanding the foregoing, the restrictions contained in this Section 5(g) shall not apply to, prohibit or in any way restrict,
or be deemed to prohibit or in any way restrict, (i) the issuance by the Company of shares of Common Stock issued pursuant to employee
benefit plans, qualified stock option plans, other employee compensation plans or non-employee director compensation programs (collectively,
 “Compensation Plans”) existing on the date hereof and disclosed in the Pricing Disclosure Package or
pursuant to outstanding options, warrants or rights existing on the date hereof and disclosed in the Pricing Disclosure Package;
(ii) the grant of options and other equity awards pursuant to Compensation Plans existing on the date hereof and disclosed in the
Pricing Disclosure Package; (iii) the filing of any registration statement on Form S-8 to register shares of Common Stock reserved
for issuance under Compensation Plans existing on the date hereof and disclosed in the Pricing Disclosure Package; (iv) the issuance
of the Notes pursuant to this Agreement; (v) shares of Common Stock issued by the Company upon conversion of the Notes or any other
outstanding convertible notes issued by the Company and outstanding on the date hereof and disclosed in the Pricing Disclosure
Package; and (vi) the issuance by the Company of shares of Common Stock or securities convertible into, exchangeable for or that
represent the right to receive Common Stock in connection with (1) the acquisition by the Company or any of its subsidiaries of
the securities, business, technology, property or other assets of another person or entity or pursuant to an employee benefit plan
assumed by the Company in connection with such acquisition and (2) the Company’s joint ventures, equipment leasing arrangements,
licensing transactions, collaborations, debt financings and other strategic transactions; provided that the aggregate number of
shares of Common Stock that the Company may sell or issue or agree to sell or issue pursuant to this clause (vi) shall not exceed
5% of the total number of shares of Common Stock outstanding immediately following the completion of the transactions contemplated
by this Agreement and the Company shall cause each recipient of such securities to execute and deliver to Barclays, on behalf of
the Initial Purchasers, on or prior to the issuance of such securities, a lock-up agreement substantially in the form of Exhibit
A hereto to the extent and for the duration that such terms remain in effect at the time of the transfer.


 






    	 	18	 



     


    

 


(h)              
Between the date hereof and the Closing Date (both dates included), the Company will not do any act or thing which, had
the Firm Notes then been in issue, would result in an adjustment to the conversion price of the Firm Notes.


 


(i)                While
the Notes or the Underlying Common Stock remain outstanding and are “restricted securities” within the meaning of
Rule 144(a)(3) under the Securities Act, the Company will, during any period in which the Company is not subject to and in compliance
with Section 13 or 15(d) of the Exchange Act, furnish or otherwise make available at its expense to the Initial Purchasers, and,
upon request, to the holders of the Notes or the Underlying Common Stock and prospective purchasers of the Notes or the Underlying
Common Stock the information required by Rule 144A(d)(4) (if any).


 


(j)                The
Company will apply the net proceeds from the sale of the Notes to be sold by it hereunder substantially in accordance with the
description set forth in the Pricing Disclosure Package and the Offering Memorandum under the caption “Use of Proceeds.”


 


(k)              
The Company and its controlled affiliates will not take, directly or indirectly, any action designed to or that has constituted
or that reasonably could be expected to cause or result in the stabilization or manipulation of the price of any security of the
Company in connection with the offering of the Notes.


 


(l)                The
Company will use its reasonable best efforts to permit the Notes to be eligible for clearance and settlement through DTC.


 






    	 	19	 



     


    

 


(m)              The Company will not, and will not permit any of its controlled affiliates (as defined in Rule 144 under the Securities
Act) to, resell any of the Notes that have been acquired by any of them, except for Notes purchased by the Company or any of its
controlled affiliates and resold in a transaction registered under the Securities Act.


 


(n)              
The Company agrees not to sell, offer for sale or solicit offers to buy or otherwise negotiate in respect of any security
(as defined in the Securities Act) that would be integrated with the sale of the Notes in a manner that would require the registration
under the Securities Act of the sale to the Initial Purchasers or the Eligible Purchasers of the Notes. The Company will take reasonable
precautions designed to insure that any offer or sale, direct or indirect, in the United States or to any U.S. person (as defined
in Rule 902 under the Securities Act) of any Notes or any substantially similar security issued by the Company, within six months
subsequent to the date on which the distribution of the Notes has been completed (as notified to the Company by the Initial Purchasers),
is made under restrictions and other circumstances reasonably designed not to affect the status of the offer and sale of the Notes
contemplated by this Agreement as transactions exempt from the registration provisions of the Securities Act, including any sales
pursuant to Rule 144A or Regulation D.


 


(o)              
In connection with any offer or sale of the Notes, the Company will not engage, and will cause its controlled affiliates
and any person acting on its behalf (other than, in any case, the Initial Purchasers and any of their affiliates, as to whom the
Company make no covenant) not to engage in any form of general solicitation or general advertising (within the meaning of Regulation
D or any public offering within the meaning of Section 4(a)(2) of the Securities Act in connection with any offer or sale of the
Notes.


 


(p)              
The Company agrees to comply in all material respects with all agreements set forth in the representation letters of the
Company to DTC relating to the approval of the Notes by DTC for “book entry” transfer.


 


(q)             
The Company will do and perform all things required or necessary to be done and performed under this Agreement by it prior
to the Closing Date, and to satisfy all conditions precedent to the Initial Purchasers’ obligations hereunder to purchase
the Notes.


 


(r)               
The Company agrees to reserve and keep available at all times, free of preemptive rights, a sufficient number of Underlying
Common Stock to enable the Company to satisfy any obligations to issue Underlying Common Stock upon conversion of the Notes.


 


(s)               
Between the date hereof and the Closing Date, the Company will
not do or authorize any act that would result in an adjustment of the conversion rate of the Notes.


 


(t)                The
Company agrees to use its best efforts to list, subject to notice of issuance, the Underlying Common Stock issuable upon conversion
of the Notes on the Nasdaq Global Select Market, and to maintain a transfer agent and, if necessary under the jurisdiction of
incorporation of the Company, a register for the Underlying Common Stock.


 






    	 	20	 



     


    

 


6.           Expenses.
Whether or not the transactions contemplated by this Agreement are consummated or this Agreement is terminated, the Company agrees
to pay all expenses, costs, fees and taxes incident to and in connection with: (a) the preparation, printing, filing and distribution
of the Preliminary Offering Memorandum, the Pricing Disclosure Package and the Offering Memorandum (including, without limitation,
financial statements and exhibits and one or more versions of the Preliminary Offering Memorandum and the Offering Memorandum
for distribution in Canada, including the form of a Canadian “wrapper” (but excluding reasonable legal fees and expenses
of Canadian counsel to the Initial Purchasers)) and all amendments and supplements thereto (including the fees, disbursements
and expenses of the Company’s accountants and counsel, but not, however, legal fees and expenses of the Initial Purchasers’
counsel incurred in connection therewith); (b) the preparation, printing (including, without limitation, word processing and duplication
costs) and delivery of this Agreement, the Indenture, all Blue Sky memoranda and all other agreements, memoranda, correspondence
and other documents printed and delivered in connection therewith and with the Exempt Resales (but not, however, legal fees and
expenses of the Initial Purchasers’ counsel incurred in connection with any of the foregoing); (c) the issuance and delivery
by the Company of the Notes and any taxes payable in connection therewith; (d) the qualification of the Notes for offer and sale
under the securities or Blue Sky laws of the several states, and any foreign jurisdictions as the Initial Purchasers may designate
(including, without limitation, the reasonable fees and disbursements of the Initial Purchasers’ counsel relating to such
registration or qualification in an amount not to exceed $10,000); (e) the furnishing of such copies of the Preliminary Offering
Memorandum, the Pricing Disclosure Package and the Offering Memorandum, and all amendments and supplements thereto, as may be
reasonably requested for use in connection with the Exempt Resales; (f) the preparation of certificates for the Notes (including,
without limitation, printing and engraving thereof); (g) the approval of the Notes by DTC for “book-entry” transfer
(including fees and expenses of counsel for the Initial Purchasers); (h) the rating of the Notes; (i) the obligations of the Trustee,
any agent of the Trustee and the counsel for the Trustee in connection with the Indenture and the Notes; (j) the performance by
the Company of their other obligations under this Agreement; (k) all expenses incurred by the Company (for avoidance of doubt,
excluding expenses incurred by the Initial Purchasers) in connection with any “road show” presentation to potential
investors, and (l) and expenses associated with any electronic road show.


 


7.           Conditions to Initial Purchasers’ Obligations. The respective obligations of the Initial Purchasers hereunder
are subject to the accuracy, when made and on and as of the Closing Date, of the representations and warranties of the Company
contained herein, to the performance by the Company of its obligations hereunder, and to each of the following additional terms
and conditions:


 


(a)              
The Initial Purchasers shall not have discovered and disclosed to the Company on or prior to the Closing Date that the Pricing
Disclosure Package, any Free Writing Offering Document or the Offering Memorandum, or any amendment or supplement thereto, contains
an untrue statement of a fact which, in the opinion of Fenwick & West LLP, counsel to the Initial Purchasers, is material or
omits to state a fact which, in the opinion of such counsel, is material and is necessary in order to make the statements therein,
in the light of the circumstances then prevailing, not misleading.


 


(b)              
All corporate proceedings and other legal matters incident to the authorization, form and validity of this Agreement, the
Notes, the Indenture, the Pricing Disclosure Package and the Offering Memorandum, and all other legal matters relating to this
Agreement and the transactions contemplated hereby shall be reasonably satisfactory in all material respects to counsel for the
Initial Purchasers, and the Company shall have furnished to such counsel all documents and information that they may reasonably
request to enable them to pass upon such matters.


 






    	 	21	 



     


    

 


(c)              
Wilson Sonsini Goodrich & Rosati, P.C. shall have furnished to the Initial Purchasers its written opinion and negative
assurance letter, as counsel to the Company, addressed to the Initial Purchasers and dated the Closing Date, in form and substance
satisfactory to the Initial Purchasers.


 


(d)              
Kilpatrick Townsend & Stockton LLP, shall have furnished to the Initial Purchasers its written opinion, as intellectual
property counsel to the Company, addressed to the Initial Purchasers and dated the Closing Date, in form and substance satisfactory
to the Initial Purchasers.


 


(e)             
The Initial Purchasers shall have received from Fenwick & West LLP, counsel for the Initial Purchasers, such opinion
or opinions and negative assurance letter, dated the Closing Date, with respect to the issuance and sale of the Notes, the Pricing
Disclosure Package, the Offering Memorandum and other related matters as the Initial Purchasers may reasonably require, and the
Company shall have furnished to such counsel such documents and information as such counsel reasonably requests for the purpose
of enabling them to pass upon such matters.


 


(f)               
At the time of execution of this Agreement, the Initial Purchasers shall have received from PricewaterhouseCoopers LLP a
letter, in form and substance satisfactory to the Initial Purchasers, addressed to the Initial Purchasers and dated the date hereof
(i) confirming that they are independent public accountants with respect to the Company and the Subsidiaries within the meaning
of the Securities Act and the applicable rules and regulations adopted by the Commission and the PCAOB and are in compliance with
the applicable requirements relating to the qualification of accountants under Rule 2-01 of Regulation S-X of the Commission and
(ii) stating, as of the date hereof (or, with respect to matters involving changes or developments since the respective dates as
of which specified financial information is given in the Pricing Disclosure Package, as of a date not more than three days prior
to the date hereof), the conclusions and findings of such firm with respect to the financial information and (iii) covering such
other matters as are ordinarily covered by accountants’ “comfort letters” to underwriters in connection with
registered public offerings.


 


(g)              
With respect to the letter of PricewaterhouseCoopers LLP referred to in the preceding paragraph and delivered to the Initial
Purchasers concurrently with the execution of this Agreement (the “initial letter”), the Company shall
have furnished to the Initial Purchasers a “bring-down letter” of such accountants, addressed to the Initial Purchasers
and dated the Closing Date (i) confirming that it is an independent public accountant with respect to the Company and the Subsidiaries
within the meaning of the Securities Act and the applicable rules and regulations adopted by the Commission and the PCAOB and is
in compliance with the applicable requirements relating to the qualification of accountants under Rule 2-01 of Regulation S-X of
the Commission, (ii) stating, as of the Closing Date (or, with respect to matters involving changes or developments since the respective
dates as of which specified financial information is given in each of the Pricing Disclosure Package or the Offering Memorandum,
as of a date not more than three days prior to the date of the Closing Date), the conclusions and findings of such firm with respect
to the financial information and other matters covered by the initial letter, and (iii) confirming in all material respects the
conclusions and findings set forth in the initial letter.


 






    	 	22	 



     


    

 


(h)              
The Representative shall have received on the Closing Date a certificate of the Chief Financial Officer of the Company providing
 “management comfort” on certain specified financial and statistical information contained in the Pricing Disclosure
Package and the Offering Memorandum.


 


(i)                
Except as described in the Pricing Disclosure Package and the Offering Memorandum (exclusive of any amendment or supplement
thereto), (i) neither the Company nor any of the Subsidiaries shall have sustained, since the date of the latest audited financial
statements included or incorporated by reference in the Pricing Disclosure Package and the Offering Memorandum, any loss or interference
with its business from fire, explosion, flood or other calamity, whether or not covered by insurance, or from any labor dispute
or court or governmental action, order or decree, or (ii) since such date, there shall not have been any change in the capital
stock or long-term debt of the Company or any of the Subsidiaries or any change, or any development involving a prospective change,
in or affecting the condition (financial or otherwise), results of operations, stockholders’ equity, properties, management,
business or prospects of the Company and the Subsidiaries, taken as a whole, the effect of which, in any such case described in
clause (i) or (ii), is, individually or in the aggregate, in the judgment of Barclays, so material and adverse as to make it impracticable
or inadvisable to proceed with the offering, sale or the delivery of the Notes being delivered on the Closing Date on the terms
and in the manner contemplated in the Pricing Disclosure Package and the Offering Memorandum.


 


(j)                
The Company shall have furnished or caused to be furnished to the Initial Purchasers dated as of the Closing Date a certificate
of the Chief Executive Officer and Chief Financial Officer of the Company stating:


 


(i)              
That the representations, warranties and agreements of the Company in Section 2 are true and correct on and as of the
Closing Date, and the Company has complied with all its agreements contained herein and satisfied all the conditions on its part
to be performed or satisfied hereunder at or prior to the Closing Date;


 


(ii)             
That they have examined the Pricing Disclosure Package and the Offering Memorandum, and, in their opinion, (A) the Pricing
Disclosure Package, as of the Applicable Time, and the Offering Memorandum, as of its date and as of the Closing Date, did not
and do not contain any untrue statement of a material fact and did not and do not omit to state a material fact necessary to make
the statements therein, in the light of the circumstances under which they were made, not misleading and (B) since the date of
the Pricing Disclosure Package and the Offering Memorandum, no event has occurred which should have been set forth in a supplement
or amendment to the Pricing Disclosure Package and the Offering Memorandum; and


 






    	 	23	 



     


    

 


(iii)            
To the effect of Section 7(i) (provided that no representation with respect to the judgment of Barclays need to be made)
and Section 7(k).


 


(k)              
Subsequent to the earlier of the Applicable Time and the execution and delivery of this Agreement there shall not have occurred
any of the following: (i) downgrading shall have occurred in the rating accorded the Company’s debt securities by any “nationally
recognized statistical rating organization,” as that term is used by the Commission in Section 15E under the Exchange Act,
or (ii) such organization shall have publicly announced that it has under surveillance or review, with possible negative implications,
its rating of any of the Company’s debt securities.


 


(l)                
The Notes shall be eligible for clearance and settlement through DTC.


 


(m)              
The Company and the Trustee shall have executed and delivered the Indenture, and the Initial Purchasers shall have received
an original copy thereof, duly executed by the Company and the Trustee.


 


(n)               
Subsequent to the earlier of the Applicable Time and the execution and delivery of this Agreement there shall not have occurred
any of the following: (i)(A) trading in securities generally on any securities exchange that has registered with the Commission
under Section 6 of the Exchange Act (including the New York Stock Exchange, The Nasdaq Global Select Market, The Nasdaq Global
Market or The Nasdaq Capital Market) or (B) trading in any securities of the Company on any exchange or in the over-the-counter
market in the United States, shall have been suspended or materially limited or the settlement of such trading generally shall
have been materially disrupted or minimum prices shall have been established on any such exchange or such market by the Commission,
by such exchange or by any other regulatory body or governmental authority having jurisdiction, (ii) a general moratorium on commercial
banking activities shall have been declared by federal or state authorities, (iii) the United States shall have become engaged
in hostilities, there shall have been an escalation in hostilities involving the United States or there shall have been a declaration
of a national emergency or war by the United States, or (iv) there shall have occurred such a material adverse change in general
economic, political or financial conditions, including, without limitation, as a result of terrorist activities after the date
hereof (or the effect of international conditions on the financial markets in the United States shall be such), as to make it,
in the judgment of Barclays, impracticable or inadvisable to proceed with the offering or delivery of the Notes being delivered
on the Closing Date on the terms and in the manner contemplated in the Offering Memorandum or that, in the judgment of Barclays,
could materially and adversely affect the financial markets or the markets for the Notes and other debt or equity securities.


 


(o)               The
Underlying Common Stock issuable upon conversion of the Notes shall have been duly listed, subject to notice of issuance, on the
Nasdaq Global Select Market.


 


(p)              
The Lock-Up Agreements between the Representative and the officers and directors of the Company set forth on Schedule IV,
delivered to the Representative on or before the date of this Agreement, shall be in full force and effect on the Closing Date
and the Option Closing Date, as the case may be.


 






    	 	24	 



     


    

 


(q)              
On or prior to the Closing Date, the Company shall have furnished to the Initial Purchasers such further certificates and
documents as the Initial Purchasers may reasonably request.


 


The several obligations
of the Initial Purchasers to purchase Additional Notes hereunder are subject to the delivery to the Representative on the applicable
Option Closing Date of such documents as the Representative may reasonably request with respect to the good standing of the Company,
the due authorization and issuance of the Additional Notes to be sold on such Option Closing Date and other matters related to
the issuance of such Additional Notes.


 


All opinions, letters,
evidence and certificates mentioned above or elsewhere in this Agreement shall be deemed to be in compliance with the provisions
hereof only if they are in form and substance reasonably satisfactory to counsel for the Initial Purchasers.


 


8.           
Indemnification and Contribution.


 


(a)              
The Company hereby agrees to indemnify and hold harmless each Initial Purchaser, its affiliates, directors, officers and
employees and each person, if any, who controls such Initial Purchaser within the meaning of Section 15 of the Securities
Act or Section 20 of the Exchange Act, from and against any loss, claim, damage or liability, joint or several, or any action in
respect thereof (including, but not limited to, any loss, claim, damage, liability or action relating to purchases and sales of
Notes) to which that Initial Purchaser, affiliate, director, officer, employee or controlling person may become subject, under
the Securities Act or otherwise, insofar as such loss, claim, damage, liability or action arises out of or is based upon, (i) any
untrue statement or alleged untrue statement of a material fact contained in any (A) Free Writing Offering Document, the Preliminary
Offering Memorandum, the Pricing Disclosure Package or the Offering Memorandum or in any amendment or supplement thereto, or (B)
any road show or investor presentations made to investors by the Company (whether in person or electronically) (the “Road
Show”) or (ii) the omission or alleged omission to state in any Free Writing Offering Document, the Preliminary Offering
Memorandum, the Pricing Disclosure Package or the Offering Memorandum, or in any amendment or supplement thereto, or in any Road
Show, any material fact necessary in order to make the statements therein, in the light of the circumstances under which they were
made, not misleading, and shall reimburse each Initial Purchaser and each such affiliate, director, officer, employee or controlling
person promptly upon demand for any legal or other out-of-pocket expenses reasonably incurred by that Initial Purchaser, affiliate,
director, officer, employee or controlling person in connection with investigating or defending or preparing to defend against
any such loss, claim, damage, liability or action as such expenses are incurred; provided, however, that the Company shall
not be liable in any such case to the extent that any such loss, claim, damage, liability or action arises out of, or is based
upon, any untrue statement or alleged untrue statement or omission or alleged omission made in any Free Writing Offering Document,
Preliminary Offering Memorandum, the Pricing Disclosure Package or Offering Memorandum, or in any such amendment or supplement
thereto, or in any Road Show, in reliance upon and in conformity with written information concerning such Initial Purchaser furnished
to the Company through the Representative by or on behalf of any Initial Purchaser specifically for inclusion therein, which information
consists solely of the information specified in Section 8(e). In the event that it is finally judicially determined that the Initial
Purchasers were not entitled to receive payments for legal and other expenses pursuant to this subparagraph, the Initial Purchasers
will promptly return all sums that had been advanced pursuant hereto. The foregoing indemnity agreement is in addition to any liability
that the Company may otherwise have to any Initial Purchaser or to any affiliate, director, officer, employee or controlling person
of that Initial Purchaser.


 






    	 	25	 



     


    

 



 


(b)               Each
Initial Purchaser, severally and not jointly, hereby agrees to indemnify and hold harmless the Company, its officers and employees,
each of its directors, and each person, if any, who controls the Company within the meaning of Section 15 of the Securities Act
or Section 20 of the Exchange Act, from and against any loss, claim, damage or liability, joint or several, or any action in respect
thereof, to which the Company or any such director, officer, employee or controlling person may become subject, under the Securities
Act or otherwise, insofar as such loss, claim, damage, liability or action arises out of or is based upon (i) any untrue statement
or alleged untrue statement of a material fact contained in any Free Writing Offering Document, Preliminary Offering Memorandum,
the Pricing Disclosure Package or the Offering Memorandum or in any amendment or supplement thereto, or in any Road Show, or (ii)
the omission or alleged omission to state in any Free Writing Offering Document, Preliminary Offering Memorandum, the Pricing
Disclosure Package or the Offering Memorandum, or in any amendment or supplement thereto, or in any Road Show, any material fact
necessary in order to make the statements therein, in the light of the circumstances under which they were made, not misleading,
but in each case only to the extent, that the untrue statement or alleged untrue statement or omission or alleged omission was
made in reliance upon and in conformity with written information concerning such Initial Purchaser furnished to the Company through
the Representative by or on behalf of that Initial Purchaser specifically for inclusion therein, which information is limited
to the information set forth in Section 8(e). The foregoing indemnity agreement is in addition to any liability that any Initial
Purchaser may otherwise have to the Company or any such director, officer, employee or controlling person.


 


(c)              
Promptly after receipt by an indemnified party under this Section 8 of notice of any claim or the commencement of any action,
the indemnified party shall, if a claim in respect thereof is to be made against the indemnifying party under this Section 8, notify
the indemnifying party in writing of the claim or the commencement of that action; provided, however, that the failure
to notify the indemnifying party shall not relieve it from any liability that it may have under paragraphs (a) or (b) above except
to the extent it has been materially prejudiced (through the forfeiture of substantive rights or defenses) by such failure and;
provided, further, that the failure to notify the indemnifying party shall not relieve the indemnifying party from
any liability that it may have to an indemnified party otherwise than under paragraphs (a) or (b) above. If any such claim or action
shall be brought against an indemnified party, and it shall notify the indemnifying party thereof, the indemnifying party shall
be entitled to participate therein and, to the extent that it wishes, jointly with any other similarly notified indemnifying party,
to assume the defense thereof with counsel reasonably satisfactory to the indemnified party. After notice from the indemnifying
party to the indemnified party of its election to assume the defense of such claim or action, the indemnifying party shall not
be liable to the indemnified party under this Section 8 for any legal or other expenses subsequently incurred by the indemnified
party in connection with the defense thereof other than reasonable costs of investigation; provided, however, that
the indemnified party shall have the right to employ counsel to represent jointly the indemnified party and those other indemnified
parties and their respective directors, officers, employees and controlling persons who may be subject to liability arising out
of any claim in respect of which indemnity may be sought under this Section 8, if (i) the indemnified party and the indemnifying
party shall have so mutually agreed; (ii) the indemnifying party has failed within a reasonable time to retain counsel reasonably
satisfactory to the indemnified party; (iii) the indemnified party and its directors, officers, employees and controlling persons
shall have reasonably concluded (based on the advice of counsel) that there may be legal defenses available to them that are different
from or in addition to those available to the indemnified party; or (iv) the named parties in any such proceeding (including any
impleaded parties) include both the indemnified parties or their respective directors, officers, employees or controlling persons,
on the one hand, and the indemnifying party, on the other hand, and representation of both sets of parties by the same counsel
would present a conflict due to actual or potential differing interests between them, and in any such event the fees and expenses
of such separate counsel shall be paid by the indemnifying party. No indemnifying party shall (x) without the prior written consent
of the indemnified parties (which consent shall not be unreasonably withheld, delayed, or conditioned), settle or compromise or
consent to the entry of any judgment with respect to any pending or threatened claim, action, suit or proceeding in respect of
which indemnification or contribution may be sought hereunder (whether or not the indemnified parties are actual or potential parties
to such claim or action) unless such settlement, compromise or consent includes an unconditional release of each indemnified party
from all liability arising out of such claim, action, suit or proceeding and does not include a statement as to, or an admission
of fault, culpability or a failure to act by or on behalf of any indemnified party, or (y) be liable for any settlement of any
such action effected without its written consent (which consent shall not be unreasonably withheld, delayed, or conditioned), but
if settled with the consent of the indemnifying party or if there be a final judgment of the plaintiff in any such action, the
indemnifying party agrees to indemnify and hold harmless any indemnified party from and against any loss or liability by reason
of such settlement or judgment.


 






    	 	26	 



     


    

 


(d)               If
the indemnification provided for in this Section 8 shall for any reason be unavailable to or insufficient to hold harmless an
indemnified party under Section 8(a) or 8(b) in respect of any loss, claim, damage or liability or any action in respect thereof
referred to therein, then each indemnifying party shall, in lieu of indemnifying such indemnified party, contribute to the amount
paid or payable by such indemnified party as a result of such loss, claim, damage or liability, or action in respect thereof,
(i) in such proportion as shall be appropriate to reflect the relative benefits received by the Company, on the one hand, and
the Initial Purchasers, on the other, from the offering of the Notes, or (ii) if the allocation provided by clause (i) above is
not permitted by applicable law, in such proportion as is appropriate to reflect not only the relative benefits referred to in
clause (i) above but also the relative fault of the Company, on the one hand, and the Initial Purchasers, on the other, with respect
to the statements or omissions that resulted in such loss, claim, damage or liability or action in respect thereof, as well as
any other relevant equitable considerations. The relative benefits received by the Company, on the one hand, and the Initial Purchasers,
on the other hand, with respect to such offering shall be deemed to be in the same proportion as the total net proceeds from the
offering of the Notes purchased under this Agreement (before deducting expenses) received by the Company, on the one hand, and
the total discounts and commissions received by the Initial Purchasers with respect to the Notes purchased under this Agreement,
on the other hand, bear to the total gross proceeds from the offering of the Notes under this Agreement as set forth on the cover
page of the Offering Memorandum. The relative fault shall be determined by reference to whether the untrue or alleged untrue statement
of a material fact or omission or alleged omission to state a material fact relates to information supplied by the Company, or
the Initial Purchasers, the intent of the parties and their relative knowledge, access to information and opportunity to correct
or prevent such statement or omission. The Company and the Initial Purchasers agree that it would not be just and equitable if
contributions pursuant to this Section 8(d) were to be determined by pro rata allocation (even if the Initial Purchasers were
treated as one entity for such purpose) or by any other method of allocation that does not take into account the equitable considerations
referred to herein. The amount paid or payable by an indemnified party as a result of the loss, claim, damage or liability or
action in respect thereof, referred to above in this Section 8(d) shall be deemed to include, for purposes of this Section 8(d),
any legal or other expenses reasonably incurred by such indemnified party in connection with investigating or defending any such
action or claim. Notwithstanding the provisions of this Section 8(d), no Initial Purchaser shall be required to contribute any
amount in excess of the amount by which the total underwriting discounts and commissions received by such Initial Purchaser with
respect to the offering of the Notes exceeds the amount of any damages that such Initial Purchaser has otherwise been required
to pay by reason of such untrue or alleged untrue statement or omission or alleged omission. No person guilty of fraudulent misrepresentation
(within the meaning of Section 11(f) of the Securities Act) shall be entitled to contribution from any person who was not guilty
of such fraudulent misrepresentation. The Initial Purchasers’ obligations to contribute as provided in this Section 8(d)
are several in proportion to their respective purchase obligations and not joint.


 






    	 	27	 



     


    

 


(e)               The
Initial Purchasers severally confirm and the Company acknowledges and agrees that the statements with respect to the offering
of the Notes by the Initial Purchasers set forth in the second sentence of the third paragraph and the eighth paragraph of the
section entitled “Plan of Distribution” in the Pricing Disclosure Package and the Offering Memorandum are correct
and constitute the only information concerning such Initial Purchasers furnished in writing to the Company by or on behalf of
the Initial Purchasers specifically for inclusion in the Preliminary Offering Memorandum, the Pricing Disclosure Package and the
Offering Memorandum or in any amendment or supplement thereto.


 


9.           Defaulting
Initial Purchasers.


 


(a)              
If, on the Closing Date or the Option Closing Date, as the case may be, any Initial Purchaser defaults in its obligations
to purchase the Notes that it has agreed to purchase under this Agreement, the remaining non-defaulting Initial Purchasers may
in their discretion arrange for the purchase of such Notes by the non-defaulting Initial Purchasers or other persons satisfactory
to the Company on the terms contained in this Agreement. If, within 36 hours after any such default by any Initial Purchaser, the
non-defaulting Initial Purchasers do not arrange for the purchase of such Notes, then the Company shall be entitled to a further
period of 36 hours within which to procure other persons satisfactory to the non-defaulting Initial Purchasers to purchase such
Notes on such terms. In the event that within the respective prescribed periods, the non-defaulting Initial Purchasers notify the
Company that they have so arranged for the purchase of such Notes, or the Company notifies the non-defaulting Initial Purchasers
that it has so arranged for the purchase of such Notes, either the non-defaulting Initial Purchasers or the Company may postpone
the Closing Date or the Option Closing Date, as the case may be, for up to seven full business days in order to effect any changes
that in the opinion of counsel for the Company or counsel for the Initial Purchasers may be necessary in the Pricing Disclosure
Package, the Offering Memorandum or in any other document or arrangement, and the Company agrees to promptly prepare any amendment
or supplement to the Pricing Disclosure Package or the Offering Memorandum that effects any such changes. As used in this Agreement,
the term “Initial Purchaser” includes, for all purposes of this Agreement unless the context requires otherwise, any
party not listed in Schedule I hereto that, pursuant to this Section 9, purchases Notes that a defaulting Initial Purchaser agreed
but failed to purchase.


 






    	 	28	 



     


    

 


(b)              
If, after giving effect to any arrangements for the purchase of the Notes of a defaulting Initial Purchaser or Initial
Purchasers by the non-defaulting Initial Purchasers and the Company as provided in paragraph (a) above, the aggregate principal
amount of such Notes that remains unpurchased on the Closing Date or the Option Closing Date, as the case may be, does not exceed
one-eleventh of the aggregate principal amount of all the Notes to be purchased on such date, then the Company shall have the
right to require each non-defaulting Initial Purchaser to purchase the principal amount of Notes that such Initial Purchaser agreed
to purchase hereunder on such date plus such Initial Purchaser's pro rata share (based on the principal amount
of Notes that such Initial Purchaser agreed to purchase hereunder on such date) of the Notes of such defaulting Initial Purchaser
or Initial Purchasers for which such arrangements have not been made; provided that the non-defaulting Initial Purchasers
shall not be obligated to purchase more than 110% of the aggregate principal amount of Notes that it agreed to purchase on the
Closing Date or the Option Closing Date, as the case may be, pursuant to the terms of Section 3.


 


(c)              
If, after giving effect to any arrangements for the purchase of the Notes of a defaulting Initial Purchaser or Initial Purchasers
by the non-defaulting Initial Purchasers and the Company as provided in paragraph (a) above, the aggregate principal amount of
such Notes that remains unpurchased on the Closing Date or the Option Closing Date, as the case may be, exceeds one-eleventh of
the aggregate principal amount of all the Notes to be purchased on such date, or if the Company shall not exercise the right described
in paragraph (b) above, then this Agreement or, with respect to the Option Closing Date, the obligation of the Initial Purchasers
to purchase Additional Notes on the Option Closing Date, as the case may be, shall terminate without liability on the part of the
non-defaulting Initial Purchasers. Any termination of this Agreement pursuant to this Section 9 shall be without liability on the
part of the Company, except that the Company will continue to be liable for the payment of expenses as set forth in Sections 6
and 11 and except that the provisions of Section 8 shall not terminate and shall remain in effect.


 


(d)               Nothing
contained herein shall relieve a defaulting Initial Purchaser of any liability it may have to the Company or any non-defaulting
Initial Purchaser for damages caused by its default.


 


10.         Termination.
The obligations of the Initial Purchasers hereunder may be terminated by the Initial Purchasers by notice given to and received
by the Company prior to delivery of and payment for the Notes if, prior to that time, any of the events described in Sections
7(i), (k) or (n) shall have occurred or if the Initial Purchasers shall decline to purchase the Notes for any reason permitted
under this Agreement.


 






    	 	29	 



     


    

 


11.         Reimbursement
of Initial Purchasers’ Expenses. If (a) the Company for any reason fails to tender the Notes for delivery to the Initial
Purchasers, or (b) the Initial Purchasers decline to purchase the Notes for any reason permitted under this Agreement, the Company
shall reimburse the Initial Purchasers for all reasonable out-of-pocket expenses (including fees and disbursements of counsel
for the Initial Purchasers) incurred by the Initial Purchasers in connection with this Agreement and the proposed purchase of
the Notes, and upon demand the Company shall pay the full amount thereof to the Initial Purchasers. If this Agreement is terminated
pursuant to Section 9 by reason of the default of one or more Initial Purchasers, the Company shall not be obligated to reimburse
any defaulting Initial Purchaser on account of those expenses.


 


12.           Notices,
etc. All statements, requests, notices and agreements hereunder shall be in writing, and:


 


(a)              
if to any Initial Purchasers, shall be delivered or sent by hand delivery, mail, overnight courier or facsimile transmission
to Barclays Capital Inc., 745 Seventh Avenue, New York, New York 10019, Attention: Syndicate Registration (Fax: (646) 834-8133)
with a copy to Fenwick & West LLP, 801 California Street, Mountain View, California 94041, Attention: David Michaels, and with
a copy, in the case of any notice pursuant to Section 8(c), to the Director of Litigation, Office of the General Counsel, Barclays
Capital Inc., 745 Seventh Ave., New York, New York 10019;


 


(b)               if
to the Company, shall be delivered or sent by mail, telex, overnight courier or facsimile transmission to Fluidigm Corporation,
7000 Shoreline Court, Suite 100, South San Francisco, California 94080, Attention: General Counsel, with a copy to Wilson, Sonsini,
Goodrich & Rosati, P.C., 950 Page Mill Road, Palo Alto, California 94304, Attention: Robert Kornegay and Michael Occhiolini;


 


Any such statements,
requests, notices or agreements shall take effect at the time of receipt thereof. The Company shall be entitled to act and rely
upon any request, consent, notice or agreement given or made on behalf of the Initial Purchasers by Barclays Capital Inc.


 


13.         Persons
Entitled to Benefit of Agreement. This Agreement shall inure to the benefit of and be binding upon the Initial Purchasers,
the Company, and their respective successors. This Agreement and the terms and provisions hereof are for the sole benefit of only
those persons, except that the representations, warranties, indemnities and agreements of the Company contained in this Agreement
shall also be deemed to be for the benefit of affiliates, directors, officers and employees of the Initial Purchasers and each
person or persons, if any, controlling any Initial Purchaser within the meaning of Section 15 of the Securities Act. Nothing in
this Agreement is intended or shall be construed to give any person, other than the persons referred to in this Section 13, any
legal or equitable right, remedy or claim under or in respect of this Agreement or any provision contained herein.


 






    	 	30	 



     


    

 


14.         Survival.
The respective indemnities, rights of contribution, representations, warranties and agreements of the Company and the Initial
Purchasers contained in this Agreement or made by or on behalf of them, respectively, pursuant to this Agreement, shall survive
the delivery of and payment for the Notes and shall remain in full force and effect, regardless of any termination of this Agreement
or any investigation made by or on behalf of any of them or any person controlling any of them


 


15.         Definition
of the Terms “Business Day” and “Affiliate”. For purposes of this Agreement, (a) “business day”
means any day on which the New York Stock Exchange, Inc. is open for trading, and (b) “affiliate” has the meaning
set forth in Rule 405 under the Securities Act.


 


16.         Governing
Law & Venue. This Agreement and any claim, controversy or dispute arising under or related to this Agreement shall
be governed by and construed in accordance with the laws of the State of New York. The Company and each of the Initial Purchasers
agree that any suit, action or proceeding arising out of or based upon this Agreement or the transactions contemplated hereby
may be instituted in any State or U.S. federal court in The City of New York and County of New York, and waives any objection
that such party may now or hereafter have to the laying of venue of any such proceeding, and irrevocably submits to the exclusive
jurisdiction of such courts in any suit, action or proceeding.


 


17.         Waiver
of Jury Trial. The Company and each of the Initial Purchasers hereby irrevocably waives, to the fullest extent permitted by
applicable law, any and all right to trial by jury in any legal proceeding arising out of or relating to this Agreement or the
transactions contemplated hereby.


 


18.         No
Fiduciary Duty. The Company acknowledges and agrees that in connection with this offering, or any other services the Initial
Purchasers may be deemed to be providing hereunder, notwithstanding any preexisting relationship, advisory or otherwise, between
the parties or any oral representations or assurances previously or subsequently made by the Initial Purchasers: (a) no fiduciary
or agency relationship exists between the Company and any other person, on the one hand, and the Initial Purchasers, on the other
hand; (b) the Initial Purchasers are not acting as advisors, expert or otherwise, to the Company, including, without limitation,
with respect to the determination of the purchase price of the Notes, and such relationship between the Company, on the one hand,
and the Initial Purchasers, on the other hand, is entirely and solely commercial, based on arms-length negotiations; (c) any duties
and obligations that the Initial Purchasers may have to the Company shall be limited to those duties and obligations specifically
stated herein; (d) the Initial Purchasers and their respective affiliates may have interests that differ from those of the Company;
and (e) the Company has consulted its own legal and financial advisors to the extent they deemed appropriate. The Company hereby
waives any claims that the Company may have against the Initial Purchasers with respect to any breach of fiduciary duty in connection
with the Notes.


 


19.         Counterparts.
This Agreement may be executed in one or more counterparts and, if executed in more than one counterpart, the executed counterparts
shall each be deemed to be an original but all such counterparts shall together constitute one and the same instrument.


 






    	 	31	 



     


    

 


20.         Headings. The headings herein are inserted for convenience of reference only and are not intended to be part of,
or to affect the meaning or interpretation of, this Agreement.


 


21.         Recognition
of the U.S. Special Resolution Regimes. 


 


(a)       In
the event that any of the Initial Purchasers that are a Covered Entity becomes subject to a proceeding under a U.S. Special Resolution
Regime, the transfer from such Initial Purchaser of this Agreement, and any interest and obligation in or under this Agreement,
will be effective to the same extent as the transfer would be effective under the U.S. Special Resolution Regime if this Agreement,
and any such interest and obligation, were governed by the laws of the United States or a state of the United States.


 


(b)       In
the event that any Initial Purchasers that are a Covered Entity or a BHC Act Affiliate of such Initial Purchaser becomes subject
to a proceeding under a U.S. Special Resolution Regime, Default Rights under this Agreement that may be exercised against such
Initial Purchaser are permitted to be exercised to no greater extent than such Default Rights could be exercised under the U.S.
Special Resolution Regime if this Agreement were governed by the laws of the United States or a state of the United States.


 


(c)       As
used in this Agreement:


 


(i)        “BHC
Act Affiliate” has the meaning assigned to the term “affiliate” in, and shall be interpreted in accordance
with, 12 U.S.C. § 1841(k).


 


(ii)        “Covered
Entity” means any of the following:


 


(x)       a
 “covered entity” as that term is defined in, and interpreted in accordance with, 12 C.F.R. § 252.82(b);


 


(y)       a
 “covered bank” as that term is defined in, and interpreted in accordance with, 12 C.F.R. § 47.3(b); or


 


(z)       a
 “covered FSI” as that term is defined in, and interpreted in accordance with 12 C.F.R. § 382.2(b).


 


(iii)       “Default
Right” has the meaning assigned to that term in, and shall be interpreted in accordance with, 12 C.F.R. §§
252.81, 47.2 or 382.1, as applicable.


 


(iv)       “U.S.
Special Resolution Regime” means each of (i) the Federal Deposit Insurance Act and the regulations promulgated thereunder
and (ii) Title II of the Dodd-Frank Wall Street Reform and Consumer Protection Act and the regulations promulgated thereunder.


 






    	 	32	 



     


    

 


If the foregoing correctly
sets forth the agreement among the Company and the Initial Purchasers, please indicate your acceptance in the space provided for
that purpose below.


 


	 	Very
    truly yours,
	 	 
	 	Fluidigm
    Corporation




 


	 	By 	/s/ Vikram Jog
	 	 	Name: Vikram Jog
	 	 	Title: Chief Financial Officer




 


Accepted:


 


Barclays
Capital Inc.


 


	By	/s/
    Steven R. Halperin	 
	 	Name:
    Steven R. Halperin	 
	 	Title:
    Managing Director	 




 






    	 	33	 



     


    

 


SCHEDULE I


 


	Initial Purchasers	 	Principal

 Amount of 

Firm Notes

 to be 

Purchased 	 
	Barclays Capital
    Inc.	 	$	50,000,000	 
	Total	 	$	50,000,000	 




 






    	 	Schedule I - 1	 



     


    

 


Schedule
II


  


FLUIDIGM CORPORATION


FORM PRICING TERM SHEET


 






     

     


    

 




 


	PRICING TERM SHEET	 	STRICTLY CONFIDENTIAL




DATED November 20, 2019


 


 


Fluidigm Corporation


  


$50,000,000 PRINCIPAL
AMOUNT OF


 


5.25% CONVERTIBLE
SENIOR NOTES DUE 2024


 


The information
in this pricing term sheet supplements Fluidigm’s preliminary offering memorandum, dated November 20, 2019 (the “Preliminary
Offering Memorandum”), and supersedes the information in the Preliminary Offering Memorandum to the extent inconsistent with
the information in the Preliminary Offering Memorandum. In all other respects, this term sheet is qualified in its entirety by
reference to the Preliminary Offering Memorandum, including all other documents incorporated by reference therein. References to
 “we,” “our” and “us” refer to Fluidigm Corporation and not to its consolidated subsidiaries.
Terms used herein but not defined herein shall have the respective meanings as set forth in the Preliminary Offering Memorandum.
All references to dollar amounts are references to U.S. dollars.


  


	Issuer:	Fluidigm Corporation 
	 	 
	Ticker/Exchange for Common Stock:	“FLDM”/The Nasdaq Global Select Market.
	 	 
	Securities:	5.25% Convertible Senior Notes due 2024 (the “notes”).
	 	 
	Principal Amount:	$50,000,000
	 	 
	Option to Purchase Additional Notes:	$5,000,000
	 	 
	Maturity:	December 1, 2024, unless earlier converted by the holder, converted by us pursuant to our company conversion option, or repurchased in accordance with their terms.
	 	 
	Interest: 	
        5.25% per year.

         

        Interest will accrue
        from November 22, 2019 and will be payable semiannually in arrears on June 1 and December 1 of each year, beginning on June 1,
        2020. We will pay additional interest, if any, at our election as the sole remedy relating to the failure to comply with our reporting
        obligations as described under “Description of Notes — Events of Default” and under the circumstances described
        under “Description of Notes — No Registration Rights; Additional Interest” in the Preliminary Offering Memorandum.

        




 





 






     

     


    

 


 


	Conversion Rights by the Holder:	
        Holders may convert their
        notes, in integral multiples $1,000 principal amount into shares of common stock at the then-applicable conversion rate at any
        point prior to the close of business on the second scheduled trading day immediately preceding the maturity date.

         

        Upon conversion of the
        notes, we will deliver on the second scheduled trading day following the relevant conversion date, a number of shares of common
        stock equal to (i) the aggregate principal amount of notes to be converted, divided by $1,000 multiplied by (ii) the then-applicable
        conversion rate for each $1,000 principal amount of notes; provided, however, that for any conversion that occurs on or after the
        record date for the payment of interest on the notes at maturity, we will deliver such shares on the maturity date

	 	 
	Conversion Rights by the Company: 	
        We may not convert the notes prior to December
        1, 2021.

         

        On or after December 1, 2021 to December
        1, 2022, we may convert all but not less than all the notes, at our option, if the VWAP of our common stock has been at least 150%
        of the conversion price then in effect for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day
        period (including the last trading day of such period) ending on and including, the trading day immediately preceding the date
        on which we provide a notice of conversion (an “early company conversion”). If we convert the notes pursuant to an
        early company conversion prior to December 1, 2022, we will increase the conversion rate as described in “Description of
        Notes—Conversion Rights—Increase in Conversion Rate upon Conversion upon a Make-Whole Fundamental Change or Notice
        of Early Company Conversion” in the Preliminary Offering Memorandum.

         

        On or after December 1, 2022, we may convert
        all but not less than all the notes, at our option, if the VWAP of our common stock has been at least 130% of the conversion price
        then in effect for at least 20 trading days (whether or not consecutive) during any 30 consecutive trading-day period (including
        the last trading day of such period) ending on and including, the trading day immediately preceding the date on which we provide
        a notice of conversion.

	 	 
	Redemption:	We may not redeem the notes prior to maturity.  No sinking fund is provided for the notes. 
	 	 
	Fundamental Change:	If a “fundamental change” (as defined under “Description of Notes—Fundamental Change Permits Holders to Require Us to Repurchase Notes” in the Preliminary Offering Memorandum) occurs at any time prior to the maturity date of the notes, holders will have the right, at their option, to require us to repurchase for cash all of their notes, or any portion of the principal amount thereof that is equal to $1,000 or an integral multiple of $1,000.  The fundamental change repurchase price we are required to pay will be equal to 100% of the principal amount of the notes to be repurchased, plus accrued and unpaid interest to, but excluding, the fundamental change repurchase date.  See “Description of Notes—Fundamental Change Permits Holders to Require Us to Repurchase Notes” in the Preliminary Offering Memorandum.



 



 







     

     


    

 


 


	Regular Record Dates:	May 15 and November 15 of each year (whether or not a business day), immediately preceding the relevant June 1 or December 1 interest payment date, as the case may be.
	 	 
	Issue Price:	100% of the principal, plus accrued interest, if any, from November 22, 2019 if settlement occurs after that date.
	 	 
	Last Reported Sale Price of our Common Stock on The Nasdaq Global Select Market on November 19, 2019:	$2.32 per share.
	 	 
	Initial Conversion Rate:	344.8276 shares of our common stock per $1,000 principal amount of notes, subject to adjustment.
	 	 
	Initial Conversion Price:	Approximately $2.90 per share of our common stock, subject to adjustment.
	 	 
	Conversion Premium:	Approximately 25% above the last reported sale price of our common stock on The Nasdaq Global Select Market on November 19, 2019.
	 	 
	Settlement Method:	Shares of our common stock, as described in the Preliminary Offering Memorandum.
	 	 
	Sole Book-Running Manager:	Barclays Capital Inc.
	 	 
	Pricing Date:	November 20, 2019.
	 	 
	Trade Date:	November 20, 2019.
	 	 
	Expected Settlement Date:	November 22, 2019 (T+2).
	 	 
	CUSIP number (144A):	34385P AE8
	 	 
	ISIN (144A):	US34385PAE88
	 	 
	Listing:	None.
	 	 
	Use of Proceeds:	
        We estimate that the net proceeds from
        this offering will be approximately $47.8 million (or $52.6 million if the initial purchasers exercise their option to purchase
        additional notes in full), after deducting the initial purchasers’ discounts and estimated offering expenses payable by us.

         

        We intend to use the net proceeds from
        this offering, together with cash on hand, if required, to repurchase up to approximately $50 million aggregate principal amount
        of the 2.75% Senior Convertible Notes due 2034 (the “2014 Notes”) in negotiated transactions with institutional investors
        concurrently with this offering.

         

        We intend to use the remaining net proceeds
        from this offering after repurchase of the 2014 Notes, if any, for working capital and other general corporate purposes, which
        may include capital expenditures, the repurchase or retirement of any remaining 2014 Notes, potential acquisitions and strategic
        transactions. However, we have not designated any specific uses and have no current agreements with respect to any material acquisition
        or strategic transaction.

         

        If the initial purchasers exercise their
        option to purchase additional notes, we expect to use the net proceeds from the sale of additional notes for working capital and
        other general corporate purposes as described above.

         

        See “Use of proceeds” in the
        Preliminary Offering Memorandum.

	 	 




 






     

     


    

 


 


Description of Notes—

Increase in Conversion Rate upon Conversion upon a Make-Whole Fundamental Change or Notice of Early Company Conversion


 


Holders who convert their notes in connection with a make-whole
fundamental change occurring prior to the maturity date or in connection with a notice of an early company conversion prior to
December 1, 2022 with respect to any or all of the notes as provided for in the Preliminary Offering Memorandum under “Description
of Notes—Conversion Right by Fluidigm” are entitled to an increase in the conversion rate for the notes so surrendered
for conversion.


 


The following table sets forth the number
of additional shares by which the conversion rate for the notes will be increased per $1,000 principal amount of notes for each
stock price and effective date set forth below:


 





	 	 Stock Price
	Effective Date	$2.32 	$2.50 	$2.90 	$3.25 	$3.77 	$4.00 	$4.35 	$6.00 	$8.00 	$10.00 
	November 22, 2019	86.2068	86.2068	79.9253	64.7524	49.1535	44.0383	37.7087	21.0180	12.6349	8.4890
	December 1, 2020	86.2068	86.2068	70.7638	55.3632	40.0858	35.2498	29.4229	15.2146	8.9333	6.0307
	December 1, 2021	86.2068	85.8330	57.9014	41.9691	27.1517	22.7920	17.8439	7.8069	4.5320	3.1507
	December 1, 2022	86.2068	76.9837	42.6056	21.3888	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000
	December 1, 2023	86.2068	73.1674	39.0515	19.2050	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000
	December 1, 2024	86.2068	55.1724	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000	0.0000







 


The exact stock prices and effective dates
may not be set forth in the table above, in which case:


 


		·	If the stock price is between two stock
prices in the table or the effective date is between two effective dates in the table, the number of additional shares by which
the conversion rate for the notes will be increased will be determined by a straight-line interpolation between the number of additional
shares set forth for the higher and lower stock prices and the earlier and later effective dates, as applicable, based on a 365-day
year. 



 


		·	If the stock price is greater than $10.00
per share (subject to adjustment in the same manner as the stock prices set forth in the column headings of the table above), no
additional shares will be added to the conversion rate for the notes.



 


		·	If the stock price is less than $2.32
per share (subject to adjustment in the same manner as the stock prices set forth in the column headings of the table above), no
additional shares will be added to the conversion rate for the notes.



 


Notwithstanding the foregoing, in no event
will the conversion rate per $1,000 principal amount of notes exceed 431.0344 shares of common stock, subject to adjustment
in the same manner as the conversion rate as set forth under “Description of Notes—Conversion Rate Adjustments”
in the Preliminary Offering Memorandum.


 


Our obligation to increase the conversion
rate for notes converted in connection with a make-whole fundamental change or notice of early company conversion could be considered
a penalty, in which case the enforceability thereof would be subject to general principles of reasonableness and equitable remedies.


 



 






     

     


    

 

 


 

 





__________________


 


This communication
is intended for the sole use of the person to whom it is provided by the sender. This material is confidential and is for your
information only and is not intended to be used by anyone other than you. This information does not purport to be a complete description
of either series of notes or the offering. This communication does not constitute an offer to sell or the solicitation of an offer
to buy any notes in any jurisdiction to any person to whom it is unlawful to make such offer or solicitation in such jurisdiction.



 


The notes and any
shares of common stock issuable upon conversion of the notes have not been and will not be registered under the U.S. Securities
Act of 1933, as amended (the “Securities Act”), or any other securities laws, and may not be offered or sold within
the United States or any other jurisdiction, except pursuant to an exemption from, or in a transaction not subject to, the registration
requirements of the Securities Act and any other applicable securities laws. The initial purchasers are initially offering the
notes only to qualified institutional buyers as defined in, and in reliance on, Rule 144A under the Securities Act. 


 


The notes and any
shares of common stock issuable upon conversion of the notes are not transferable except in accordance with the restrictions described
under the captions “Notice to Investors” and “Transfer Restrictions” in the Preliminary Offering Memorandum.


 


A copy of the Preliminary
Offering Memorandum for the offering of the notes may be obtained by contacting Barclays Capital Inc., c/o
Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, by calling (888) 603-5847, or by email at barclaysprospectus@broadridge.com.


 


Any legends, disclaimers
or other notices that may appear below are not applicable to this communication and should be disregarded. Such legends, disclaimers
or other notices have been automatically generated as a result of this communication having been sent via Bloomberg or another
system.


 


 



 


 






     

     


    

 


SCHEDULE III


 


A.       Insert
list of each document provided as an amendment or supplement to the Preliminary Offering Memorandum.


 


B.       Insert
list of any “road show” materials that are Free Writing Offering Documents.


 






    	 	Schedule III - 1	 



     


    

 





Schedule IV


 


LIST OF PERSONS SUBJECT TO LOCK-UP


 


Gerhard F. Burbach


Nicolas Barthelemy


Laura M. Clague


Samuel D. Colella


Bill Colston


Patrick S. Jones


Stephen Christopher Linthwaite


Carlos Paya


Vikram Jog


Nicholas Khadder


Bradley Kreger


Colin McCracken


 






    	 	Schedule IV - 1	 



     


    

 


Schedule V


 


SUBSIDIARIES


 


FLUIDIGM CANADA INC.


FLUIDIGM (SHANGHAI) INSTRUMENT TECHNOLOGY
CO., LTD.


FLUIDIGM FRANCE SARL


FLUIDIGM GMBH


FLUIDIGM K.K. 


FLUIDIGM EUROPE B.V.


FLUIDIGM SINGAPORE PTE. LTD.


FLUIDIGM UK LIMITED

FLUIDIGM SCIENCES INC.


 






    	 	Schedule V - 1	 



     


    

 


Exhibit A


 


Form of Lock-Up Agreement


 


Lock-Up Agreement


 


[               ], 2019


 


Barclays Capital Inc.


As representative of the several initial purchasers named


in Schedule I to the Purchase Agreement referred to below


 


c/o Barclays Capital Inc.

745 Seventh Avenue

New York, New York 10019


 


Dear Sirs:


 


As an inducement to
the initial purchasers (the “Initial Purchasers”) to execute a purchase agreement (the “Purchase
Agreement”) providing for an offering (the “Offering”) of convertible senior notes (the
 “Notes”), which will be convertible into shares of common stock (the “Common Stock”),
of Fluidigm Corporation, a Delaware corporation, and any successor (by merger or otherwise) thereto (the “Company”),
the undersigned hereby agrees that without, in each case, the prior written consent of Barclays Capital Inc. (“Barclays”),
as representative of the Initial Purchasers, during the period specified in the second succeeding paragraph (the “Lock-Up
Period”), the undersigned will not: (1) offer, pledge, announce the intention to sell, sell, contract to sell, sell
any option or contract to purchase, purchase any option or contract to sell, grant any option, right or warrant to purchase, make
any short sale or otherwise transfer or dispose of, directly or indirectly, any shares of Common Stock or any securities convertible
into, exercisable or exchangeable for or that represent the right to receive Common Stock (including without limitation, Common
Stock which may be deemed to be beneficially owned by the undersigned in accordance with the rules and regulations of the Securities
and Exchange Commission and securities which may be issued upon exercise of a stock option or warrant) whether now owned or hereafter
acquired (the “Undersigned’s Securities”); (2) enter into any swap or other agreement that transfers,
in whole or in part, any of the economic consequences of ownership of the Undersigned’s Securities, whether any such transaction
described in clause (1) or (2) above is to be settled by delivery of Common Stock or such other securities, in cash or otherwise;
(3) make any demand for or exercise any right with respect to, the registration of any Common Stock or any security convertible
into or exercisable or exchangeable for Common Stock; or (4) publicly disclose the intention to do any of the foregoing.


 


The undersigned agrees
that the foregoing restrictions preclude the undersigned from engaging in any hedging or other transaction which is designed to
or which reasonably could be expected to lead to or result in a sale or disposition of the Undersigned’s Securities even
if such securities would be disposed of by someone other than the undersigned. Such prohibited hedging or other transactions would
include without limitation any short sale or any purchase, sale or grant of any right (including without limitation any put or
call option) with respect to any of the Undersigned’s Securities or with respect to any security that includes, relates to,
or derives any significant part of its value from the Undersigned’s Securities.


 






    	 	Exhibit A-1	 



     


    

 


The Lock-Up Period
will commence on the date of this Agreement and continue and include the date seventy-five (75) days after the date of the final
offering memorandum used to sell Notes in the Offering pursuant to the Purchase Agreement.


 


Notwithstanding the
foregoing, the undersigned may transfer the Undersigned’s Securities (i) as a bona fide gift or gifts, (ii) to any
trust for the direct or indirect benefit of the undersigned or the immediate family of the undersigned, (iii) to any corporation,
partnership, limited liability company or other entity, all of the beneficial ownership interests of which, in each case, are held
by the undersigned or any immediate family of the undersigned, (iv) if the undersigned is a corporation, partnership, limited liability
company, trust or other business entity (1) transfers to another corporation, partnership, limited liability company, trust or
other business entity that is a direct or indirect affiliate (as defined in Rule 405 promulgated under the Securities Act of 1933,
as amended) of the undersigned or (2) distributions of shares of Common Stock or any security convertible into or exercisable for
Common Stock to limited partners, limited liability company members or stockholders or trust beneficiaries of the undersigned,
(v) if the undersigned is a trust, transfers to the beneficiary of such trust, (vi) transfers by testate succession or intestate
succession, (vii) transfers by operation of law, including pursuant to a qualified domestic relations order or in connection with
a divorce settlement, (viii) any transfers in connection with a bona fide third party tender offer, merger, consolidation or other
similar transaction made to all common stockholders and resulting in a Change of Control of the Company, provided that in the event
the tender offer, merger, consolidation or other such transaction is not completed, the Undersigned’s Securities shall remain
subject to the restrictions contained herein, (ix) pursuant to a 10b5-1 Plan established prior to the date hereof; or (x) pursuant
to the Purchase Agreement; provided, in the case of clauses (i)-(vi), that (x) such transfer shall not involve a disposition
for value, (y) the transferee agrees in writing with Barclays on behalf of the Initial Purchasers to be bound by the terms of this
Lock-Up Agreement, and (z) no filing by any party under Section 16(a) of the Securities Exchange Act of 1934, as amended (the “Exchange
Act”), shall be required or shall be made voluntarily in connection with such transfer (other than a Form 5 required
to be filed under the Exchange Act if the undersigned is subject to Section 16 reporting with respect to the Company under the
Exchange Act for which the deadline falls during the Lock-Up Period, and indicating by footnote disclosure or otherwise the nature
of the transfer or disposition). For purposes of this Agreement, (i) “immediate family” shall mean any
relationship by blood, marriage or adoption, not more remote than first cousin and (ii) “Change of Control”
shall mean the transfer (whether by tender offer, merger, consolidation or other similar transaction), in one transaction or a
series of related transactions, to a person or group of affiliated persons, of the Company’s voting securities if, after
such transfer, such person or group of affiliated persons would hold more than 50% of the outstanding voting securities of the
Company (or the surviving entity).


 






    	 	Exhibit A-2	 



     


    

 


In addition, the foregoing
restrictions shall not apply to (i) the exercise, conversion or exchange of any options, warrants, rights or convertible securities
outstanding on the date hereof as described in the offering memorandum (including the documents incorporated by reference therein),
including any exercise effected by the delivery or sale of the Undersigned’s Securities to the Company (including, without
limitation, to finance a “cashless exercise”); provided that it shall apply to any of the Undersigned’s Securities
issued upon such exercise, conversion or exchange, except to the extent such securities are withheld by the Company to cover tax
liabilities; or (ii) the establishment of any contract, instruction or plan (a “Plan”) that satisfies
all of the requirements of Rule 10b5-1(c)(1)(i)(B) under the Exchange Act; provided that no sales of the Undersigned’s
Securities shall be made pursuant to such a Plan prior to the expiration of the Lock-Up Period (as such may have been extended
pursuant to the provisions hereof), and such a Plan may only be established if no public announcement of the establishment or existence
thereof and no filing with the Securities and Exchange Commission or other regulatory authority in respect thereof or transactions
thereunder or contemplated thereby, by the undersigned, the Company or any other person, shall be required, and no such announcement
or filing is made voluntarily, by the undersigned, the Company or any other person, prior to the expiration of the Lock-Up Period
(as such may have been extended pursuant to the provisions hereof); or (iii) the transfer of shares of Common Stock or any securities
to the Company as forfeitures to satisfy tax withholding obligations of the undersigned or the employer of the undersigned in connection
with the vesting of restricted stock (including restricted stock units) or exercise of options held by the undersigned and granted
pursuant to the Company’s equity incentive plans that are described in the offering memorandum (including the documents incorporated
by reference therein); provided that if the undersigned is required to file a report under Section 16(a) of the Exchange Act reporting
a reduction in beneficial ownership of shares of Common Stock during the Lock-Up Period, the undersigned shall include a statement
in such report to the effect that the purpose of such transfer was to cover tax withholding obligations of the undersigned in connection
with such vesting or exercise; or (iv) transfers to a nominee, broker, or custodian of the undersigned or a person or entity to
whom a disposition or transfer would be permissible under this Agreement (provided, however, that, for the avoidance of doubt,
any such Securities so transferred shall remain subject to the restrictions provided for in this Agreement for the remainder of
the Lock-Up Period and the transferor shall continue to be responsible for ensuring compliance with the terms of this Agreement).


 


In furtherance of the
foregoing, the Company and its transfer agent and registrar are hereby authorized to decline to make any transfer of shares of
Common Stock if such transfer would constitute a violation or breach of this Agreement.


 


The undersigned hereby
represents and warrants that it: (i) has full power and authority to enter into this Agreement and that upon request, the undersigned
will execute and additional documents necessary to ensure the validity or enforcement of this Agreement, and (ii) now has, and
except as contemplated by this Agreement, for the duration of this Agreement will have, good and marketable title to the Undersigned’s
Securities, free and clear of all liens, encumbrances, and claims whatsoever. All authority herein conferred or agreed to be conferred
and any obligations of the undersigned shall be binding upon the successors, assigns, heirs or personal representatives of the
undersigned.


 


The undersigned understands
that the undersigned shall be released from all obligations under this Agreement if (i) the Company notifies the Initial Purchasers
that it does not intend to proceed with the Offering, (ii) the Purchase Agreement does not become effective, or if the Purchase
Agreement (other than the provisions thereof which survive termination) shall terminate or be terminated prior to payment for and
delivery of the Notes to be sold thereunder, or (iii) the Offering is not completed by December 31, 2019.


 






    	 	Exhibit A-3	 



     


    

 


The undersigned understands
that the Initial Purchasers are entering into the Purchase Agreement and proceeding with the Offering in reliance upon this Agreement.


 


This Agreement shall
be governed by, and construed in accordance with, the laws of the State of New York.


 


	 	Very truly yours,




 


 


	 	[Printed Name of Holder]
	 	 
	 	By:	 
	 	 	 
	 	




 






    	 	Exhibit A-4