[Federal Register Volume 66, Number 80 (Wednesday, April 25, 2001)]
[Notices]
[Pages 20794-20795]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 01-10226]


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DEPARTMENT OF ENERGY


Notice of Program Interest (NOPI)

AGENCY: Office of Isotopes for Medicine and Science, Department of 
Energy.

ACTION: Notice of Program Interest to the Public.

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SUMMARY: The U.S. Department of Energy (DOE), Office of Isotopes for 
Medicine and Research, Office of Nuclear Energy (NE) solicits responses 
for development and demonstration programs for long-term improvements 
in accelerator and/or reactor production of Ac-225/Bi-213 generators 
for use in diagnosis and therapy of cancer, and other infectious 
diseases or other innovative medical applications. The Department 
wishes to encourage development in these areas by providing resources 
in a cooperative partnering arrangement for the required development/
demonstration programs.

DATES: The complete solicitation document will be available on or about 
April 20, 2001. Any questions must be submitted to the below address by 
May 1, 2001. Applications are due May 30, 2001.

ADDRESSES: The complete solicitation document will be available on the 
DOE Industry Interactive Procurement System (IIPS) Home Page at http://doe-iips.pr.doe.gov as solicitation number DE-SC05-01OR22872. Any 
amendments to this solicitation will be posted at the IIPS site on the 
Internet and prospective proposers are responsible for checking the 
IIPS site for amendments or any additional changes to the solicitation 
as that is the only place that they will be posted.

FOR FURTHER INFORMATION CONTACT: Beth L. Holt, Contract Specialist, at 
865-576-0783, U.S. Department of Energy, P.O. Box 2001, Oak Ridge, 
Tennessee 37831-8759; by facsimile at 865 241-2549; or by e-mail at 
<a href="/cdn-cgi/l/email-protection#096166657d6b6549667b66276d666c276e667f"><span class="__cf_email__" data-cfemail="0c646360786e604c637e6322686369226b637a">[email protected]</span></a> or John J. McClure, Program Manager, Office of 
Isotopes for Medicine and Science, at 301-903-5460.

SUPPLEMENTARY INFORMATION: The Office of Isotopes for Medicine and 
Science is soliciting responses to this Notice of Program Interest for 
development and demonstration programs for long-term improvements in 
accelerator and/or reactor production of Ac-225/Bi-213 generators. 
Researchers throughout the United States are assessing alpha-emitting 
radioisotopes that can destroy cancer cells and reduce tumors. B-213 
has been effective in killing leukemia cells and shows promise in 
cancer therapy. The Department's objectives in this effort are to: (1) 
Develop an assured future supply of Bi-213; (2) maximize private 
involvement and investment with the long term objective of 
commercialization; (3) minimize future Government involvement. The 
Department wishes to encourage the private sector to be involved in the 
large scale production of these generators by providing resources in a 
cooperative partnering arrangement for the required development/
demonstration programs. The Department's financial assistance awards 
under this solicitation will be funded through cooperative agreements. 
The Department has $225,000 in FY 2001 to be divided among up to three 
awards depending on the concepts presented that best achieve our 
objectives. It is anticipated that a total of $300,000 will be 
available in each of the two subsequent years. The purchase of 
equipment and supplies will be acceptable based on reasonableness and 
contribution to the project. Applications will be subject to peer 
review by the Department's representatives. Members that participate in 
a submission or whose institutions are submitting a proposal must 
resolve conflict-of-interest concerns. Awards may be renewed upon 
submittal of an application prior to the original end date. Awards will 
be administered under the policies of the Department. The solicitation 
is available through the Industry Interactive Procurement System (IIPS) 
at http://doe-iips.pr.doe.gov. Dissemination of the solicitation, 
receipt of applications, evaluations, and the notice of award will 
occur in a paperless environment. To get more information about IIPS 
and to register your organization, go to http://doe-iips.pr.doe.gov. 
Follow the link on the IIPS home page to the Secure Services Page. 
Registration is a prerequisite to the submission of an application, and 
applicants are encouraged to register as soon as possible. When 
registering, all applicants should use the same North American Industry 
Classification System number 325412. A help document, which describes 
how IIPS works, can be found at the bottom of the Secure Services Page.


[[Page 20795]]


    Issued in Oak Ridge, Tennessee on April 16, 2001.
Charles D. Crowe,
Director, Procurement and Contracts Division, Oak Ridge Operations 
Office.
[FR Doc. 01-10226 Filed 4-24-01; 8:45 am]
BILLING CODE 6450-01-P


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