**10.81b**
 
 **GUARANTY
        OF LEASE**
 
 FOR
        V ALUE
        RECEIVED, and in consideration for, and as an inducement to Oxbridge Development
        at Crown Pointe, L.C., a Maryland limited liability company, to consent to
        an
        assignment by merger of the lease for space at 620 Professional Drive,
        Gaithersburg, Md. 20879 dated as of October 26, 2000, (the “Lease”), in which it
        is "Landlord" to GLA II Corp., a Delaware corporation (to be renamed TherImmune
        Research Corporation at the time of the merger) (“Tenant"), a wholly-owned
        subsidiary of the undersigned and successor in interest by merger to TherImmune
        Research Corporation, a Maryland corporation, the original tenant under the
        Lease, the undersigned, whether one or more, jointly and severally do hereby
        unconditionally guarantee to Landlord (i)l the punctual and full payment
        of all
        rents of every kind, additional rents and all other charges to be paid by
        Tenant
        under the Lease and (ii) the full and timely performance and observance of
        all
        the covenants, conditions, and agreements to be performed and observed by
        Tenant
        under the Lease. The undersigned shall indemnify, defend and hold harmless
        Landlord and its affiliates from any loss, damages or costs (including without
        limitation, the reasonable fees of Landlord's attorneys and court costs,
        but
        excluding any indirect, consequential, exemplary or punitive damages) arising
        out of any failure to pay the aforesaid rents and other charges or the failure
        to perform any of the aforesaid covenants, conditions and agreements under
        the
        Lease, except to the extent arising out of the negligence or intentional
        misconduct of Landlord or its agents or property manager. The undersigned
        further expressly agree that the validity of this Lease and the obligations
        of
        the undersigned hereunder shall in no way be terminated, affected or impaired
        by
        reason of any forbearances, settlements or compromises between Landlord and
        Tenant or the relief of Tenant from any of Tenant's obligations under the
        Lease
        by operation of law, such as the rejection or assignment of the Lease in
        connection with proceedings under any present or future provision of the
        federal
        Bankruptcy Act, or any similar law or statute of the United States or any
        state
        thereof.
 
 The
        undersigned further covenant and agree that this Guaranty of Lease shall
        be and
        remain in full force and effect as to any renewal, modification or extension
        of
        the Lease, whether or not known to or approved by the undersigned, but this
        Guaranty shall not remain in effect if the Tenant's interest in the Lease
        is
        assigned, with Landlord's written consent, to a third party which is not
        owned
        and controlled by the undersigned. In the event of any termination of the
        Lease
        by Landlord, the undersigned's liability hereunder shall not be terminated,
        but
        the undersigned shall be and remain fully liable for the performance of the
        Tenant's obligations, if any, under the Lease. If the undersigned shall,
        directly or indirectly, advance .any sums to Tenant, such sums and indebtedness
        shall be subordinate in all respects to the amounts then and thereafter due
        and
        owing by Tenant under the Lease.
 
 Wherever
        reference is made to the liability of Tenant in the Lease, such reference
        shall
        he deemed likewise to refer to the undersigned, jointly and severally, with
        Tenant. The liability of the undersigned for the obligations of Tenant under
        the
        Lease shall be primary, absolute and unconditional. In any right of action
        which
        shall accrue to Landlord under the Lease, Landlord may, at Landlord's option,
        proceed against any one or more of the undersigned and/or Tenant, jointly
        or
        severally, and .may proceed against any one or more of the undersigned without
        having demanded performance of, commenced any action against or having obtained
        any judgment against Tenant The undersigned hereby expressly waive: (i) notice
        of acceptance of this Guaranty of Lease and of presentment, demand and protest;
        and (ii) notice to the undersigned of any default hereunder or under the
        Lease;
        provided, however that this waiver shall not constitute a waiver of any
        obligation of the Landlord pursuant to the Lease to give Tenant notice and
        an
        opportunity to cure defaults under the Lease. This Guaranty of Lease is a
        guaranty of payment and not a guaranty of collection. The undersigned agree
        that
        in the event this Guaranty of Lease shall be enforced by suit or otherwise,
        and
        the Landlord shall prevail in any such action, the undersigned will reimburse
        the Landlord, upon demand, for an expenses incurred in connection therewith,
        including, without limitation, reasonable attorneys' fees.
 
 
  The
        undersigned hereby waive, to the maximum extent permitted bylaw, any statute.
        of
        limitations affecting the enforcement of this Guaranty of Lease.
 
 THE
        UNDERSIGNED HEREBY KNOWINGLY, VOLUNTARILY AND INTENTIONALLY WAIVE THE RIGHT
        TO A
        TRIAL BY JURY IN RESPECT OF ANY LITIGATION BASED HEREON, ARISING OUT OF,
        UNDER
        OR IN CONNECTION WITH THIS GUARANTY OF LEASE OR ANY DOCUMENTS CONTEMPLATED
        TO BE
        EXECUTED IN CONNECTION HEREWITH OR ANY COURSE OF CONDUCT, COURSE OF DEALINGS,
        STATEMENTS (WHETHER ORAL OR WRITTEN) OR ACTIONS OF THE UNDERSIGNED OR LANDLORD
        ARISING OUT OR RELATED IN ANY MANNER WITH THIS GUARANTY OF LEASE (INCLUDING
        WITHOUT LIMITATION, ANY ACTION TO RESCIND OR CANCEL THIS GUARANTY OF LEASE
        OR
        ANY CLAIMS OR DEFENSES ASSERTING THAT THIS GUARANTY OF LEASE WAS FRAUDULENTLY
        INDUCED OR IS OTHERWISE VOID OR VOIDABLE). THIS WAIVER IS A MATERIAL INDUCEMENT
        FOR LANDLORD TO CONSENT TO THE ASSIGNMENT OF THE LEASE AS DESCRIBED
        ABOVE.
 
 The
        undersigned hereby assign to Landlord any rights the undersigned may have
        to
        file a claim and proof of claim in any bankruptcy or similar proceeding of
        Tenant and any awards of payments thereon to which the undersigned would
        otherwise be entitled.
 
 It
        is
        further agreed that all of the terms and provisions hereof shall inure to
        the
        benefit of and may be enforced by the respective heirs, executors, successors
        and assigns of Landlord and the holder of any mortgage to which the Lease
        may be
        subject and subordinate from time to time, and shall be binding upon the
        respective heirs, executors, successors and assigns of the undersigned. Landlord
        may, without notice, assign this Guaranty of Lease (in connection with the
        assignment of the Lease), and no such assignment shall increase or diminish
        the
        undersigned's liability under this Guaranty of Lease.
 
 In
        the
        event more than one person or entity executes this Guaranty of Lease, the
        liability of such signatories hereunder shall be joint and several. In the
        event
        only one person or entity executes this Guaranty of Lease, an provisions
        hereof
        which refer to more than one guarantor shall be automatically modified to
        refer
        to only one guarantor, and otherwise this Guaranty of Lease shall remain
        unmodified and in full force and effect
 
 It
        is
        understood that other agreements similar to this Guaranty of Lease may, at
        Landlord's sole option and discretion, be executed by other persons with
        respect
        to the Lease. This Guaranty of Lease shall be cumulative of any such agreements
        and the liabilities and obligations of the undersigned hereunder shall in
        no
        event be affected or diminished by reason of such other agreements. Moreover,
        in
        the event Landlord obtains the signature of more than one guarantor on this
        Guaranty of Lease or obtains additional guarantee agreements, or both, the
        undersigned agree that Landlord, in Landlord's sole discretion, may (i) compound
        or settle with anyone or more of the guarantors for such consideration as
        Landlord may deem proper, and (ii) release one or more of the guarantors
        from
        liability. The undersigned further agree that no such action shall impair
        the
        rights of Landlord to enforce the Lease against any remaining guarantor or
        guarantors, including the undersigned.
 
 The
        undersigned agree to execute and deliver to Landlord, from time to time,
        upon
        ten (10) business days notice from Landlord, a certificate addressed to
        Landlord, any mortgagee or prospective mortgagee, or any prospective purchase,
        certifying (i) that this Guaranty of Lease is unmodified and in full force
        and
        effect and (ii) to such other matters as Landlord may reasonably
        request.
 
 
  If
        any
        provision of this Guaranty of Lease or the application thereof to any person
        or
        circumstance shall, for any reason and to any extent, be invalid or
        unenforceable, the remainder of this Guaranty of Lease and the application
        of
        that provision to other persons or circumstances shall not be affected but
        rather shall be enforced to the fullest extent permitted by law.
 
 If
        the
        undersigned is a corporation (including any form of professional association),
        then each individual executing or attesting this Guaranty of Lease on behalf
        of
        such corporation covenants, warrants and represents that he or she is duly
        authorized to execute or attest and deliver this Guaranty of Lease on behalf
        of
        such corporation. If the undersigned is a partnership (general or limited)
        or
        limited liability company, then each individual executing this Guaranty of
        Lease
        on behalf of the partnership or company hereby covenants, warrants and
        represents that he or she is duly authorized to execute and deliver this
        Guaranty of Lease on behalf of the partnership or company in accordance with
        the
        partnership agreement or membership agreement, as the case may be, or an
        amendment thereto, now in effect.
 
 This
        Guaranty of Lease shall be governed by the Jaws of the State of Maryland,
        exc1udingchoice of laws principles.
 
 EXECUTED
        UNDER SEAL as of the 1st day of April 2003




GUARANTOR:GENE
                LOGIC INC., a Delaware corporation
  By:
                /s/
                    Philip L. Rohrer, Jr.Name:
                Philip
                    L Rohrer, Jr.Title:
                Chief
                    Financial Officer