Wells Fargo Bank Iowa,
National]Association                                         Revolving Note
============================================================ ===================

$2,500,000.00                                                March 28, 2002

FOR VALUE RECEIVED,  Patient Infosystems,  Inc. (the "Borrower") promises to pay
to the order of Wells Fargo Bank Iowa, National Association (the "Bank"), at its
principal  office or such other address as the Bank or holder may designate from
time to time, the principal sum of TWO MILLION FIVE HUNDRED  THOUSAND and 00/100
Dollars  ($2,500,000.00),  or the  amount  shown  on the  Bank's  records  to be
outstanding,  plus interest (calculated on the basis of actual days elapsed in a
360-day year) accruing on the unpaid balance at the annual interest rate defined
below.  Absent manifest error the Bank's records will be conclusive  evidence of
the principal and accrued interest owing hereunder.

This  Revolving  Note is issued  pursuant  to an  Amended  and  Restated  Credit
Agreement  of  even  date  herewith  between  the  Bank  and the  Borrower  (the
"Agreement").  The  Agreement,  and any  amendments  or  substitutions  thereto,
contain  additional  terms and  conditions  including  default and  acceleration
provisions. The terms of the Agreement are incorporated into this Revolving Note
by  reference.  Capitalized  terms not expressly  defined  herein shall have the
meanings given them in the Agreement.

INTEREST RATE

Base Rate Option.  Unless the Borrower  chooses the LIBOR Rate Option as defined
below,  the principal  balance  outstanding  under this Revolving Note will bear
interest  at an annual  rate  equal to the Base Rate,  floating  (the "Base Rate
Option"). The Base Rate is the "base" or "prime" rate of interest established by
the Bank from time to time at its principal office in Des Moines, Iowa.

LIBOR Rate Option.  Subject to the terms and  conditions  of the  Agreement  the
Borrower  may  elect  that all or  portions  of the  principal  balance  of this
Revolving  Note bear  interest  at the LIBOR Rate plus 1.75%  (the  "LIBOR  Rate
Option"). Specific reference is made to the Section 3 of the Agreement for terms
governing the designation of interest periods and rate portions.

The LIBOR Rate will be computed in accordance with the following formula.

          LIBOR Rate =    London Interbank Rate
                            1.00 - Reserve Percentage

          Where,

          (1)  "London  Interbank  Rate"  means the  average  rate at which U.S.
               Dollar  deposits  with  a term  equal  to  the  applicable  LIBOR
               Interest  Period and in an amount equal to the LIBOR Rate Portion
               are offered to the Bank on the London Interbank Market.

          (2)  "Reserve Percentage" means the Federal Reserve System requirement
               (expressed  as a percentage)  applicable  to the dollar  deposits
               used in calculating the LIBOR Rate above.

REPAYMENT TERMS

Interest.  Interest  will be  payable on the last day of each  month,  beginning
March 31, 2002. Interest accruing under the LIBOR Rate Option will be payable at
the end of the  respectiveLIBOR  Interest  Period or the last day of each month,
whichever is earlier.

Principal.  Principal,  and any  unpaid  interest,  will be  payable in a single
payment due on March 31, 2003.

Prepayment Fee. Each prepayment of principal  amounts bearing interest under the
LIBOR Rate  Option,  whether  voluntary  or by reason of  acceleration,  will be
accompanied  by accrued  interest on the amount  prepaid plus a  prepayment  fee
equal to the amount, if any, by which:

          (1)  the  additional  interest  that  would  have been  payable on the
               amount  prepaid if it had not been paid until the last day of the
               applicable interest period, exceeds

          (2)  the  interest  that  would have been  recoverable  by the Bank by
               reinvesting  the amount prepaid from the  prepayment  date to the
               last day of the  applicable  interest  period in U.S.  Government
               Securities having a maturity date on or about that date.

ADDITIONAL  TERMS  AND  CONDITIONS.  The  Borrower  agrees  to pay all  costs of
collection,  including reasonable attorneys' fees and legal expenses incurred by
the Bank in the event this Revolving Note is not duly paid. Demand, presentment,
protest  and  notice of  nonpayment  and  dishonor  of this  Revolving  Note are
expressly  waived.  This Revolving Note will be governed by the substantive laws
of the State of Iowa.

Patient Infosystems, Inc.


By:  /s/ Kent A. Tapper
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Its: Vice President of Financial Planning
     ---------------------------------------------


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