Exhibit 32.1

| In      connection with the Quarterly Report on Form 10-Q of Centerline Holding      Company for the quarterly period ending September 30, 2009, as filed with      the Securities and Exchange Commission on the date hereof (the “Report”),      Marc D. Schnitzer, as Chief Executive Officer of our Company, and Robert      L. Levy, as Chief Financial Officer of our Company, each hereby certifies,      pursuant to 18 U.S.C. Section 1350, that: |
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   |   |   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | (1) | The      Report fully complies with the requirements of Section 13(a) or 15(d), as      applicable, of the Securities Exchange Act of 1934; and |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   |   |   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | (2) | The      information contained in the Report fairly presents, in all material      respects, the financial condition and results of operations of our      Company. |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   |   |   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   |   |   |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   |   |   |
| By:                                                                                                                                                                                                                                                                                                                                                                                                                                                                    | /s/      Marc D. Schnitzer |   | By: | /s/      Robert L. Levy |
|                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | Marc      D. SchnitzerChief      Executive Officer(Principal      Executive Officer)November      12, 2009 |   |   | Robert      L. LevyChief      Financial Officer(Principal      Financial Officer and Principal Accounting Officer)November      12, 2009 |