Exhibit 4.2

  

  

  SPECIMEN CLASS A ORDINARY SHARE CERTIFICATE

  	
          NUMBER

        	 	
          SHARES

        


  ARYA SCIENCES ACQUISITION CORP II

  INCORPORATED UNDER THE LAWS OF THE CAYMAN ISLANDS

  CLASS A ORDINARY SHARES

  

  

  SEE REVERSE FOR

  CERTAIN DEFINITIONS

  CUSIP [ ]

  

  

  This Certifies that                                         is the owner of

  

  

  FULLY PAID AND NON-ASSESSABLE CLASS A ORDINARY SHARES OF THE PAR VALUE OF

  US $0.0001 EACH OF ARYA SCIENCES ACQUISITION CORP II (THE “COMPANY”)

  

  

  subject to the Company’s amended and restated memorandum and articles of association, as the same may be amended from time to time, and
    transferable on the books of the Company in person or by duly authorized attorney upon surrender of this certificate properly endorsed.

  

  

  The Company will be forced to redeem all of its Class A ordinary shares if it is unable to complete a business combination within the
    period set forth in the Company’s amended and restated memorandum and articles of association, as the same may be amended from time to time, all as more fully described in the Company’s final prospectus dated                 , 2020.

  

  

  This certificate is not valid unless countersigned by the Transfer Agent and registered by the Registrar.

  

  

  Witness the facsimile signatures of its duly authorized officers.

  

  

  

  

  	
          Dated:

        	 	 


  

  

  	
          Chief Executive Officer

        	
          Cayman Islands

        	
          Chief Financial Officer

        
	 	 	 


  

  

  
    

    
      


    

  

  

  

  ARYA SCIENCES ACQUISITION CORP II

  

  

  The Company will furnish without charge to each shareholder who so requests the powers, designations, preferences and relative, participating, optional or other
    special rights of each class of shares or series thereof of the Company and the qualifications, limitations, or restrictions of such preferences and/or rights. This certificate and the shares represented thereby are issued and shall be held subject to
    all the provisions of the Company’s amended and restated memorandum and articles of association, as the same may be amended from time to time, and resolutions of the Board of Directors providing for the issue of Class A ordinary shares (copies of which
    may be obtained from the secretary of the Company), to all of which the holder of this certificate by acceptance hereof assents. The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though
    they were written out in full according to applicable laws or regulations:

  	
          TEN COM

        	
          —

        	
          as tenants in common

        	 	
          UNIF GIFT MIN ACT

        	
          —

        	 	
          Custodian

        	 
	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	
          (Cust)

        	 	
          (Minor)

        
	
          TEN ENT

        	
          —

        	
          as tenants by the entireties

        	 	 	 	
          under Uniform Gifts to Minors Act

        
	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	
          (State)

        	 
	
          JT TEN

        	
          —

        	
          as joint tenants with right of survivorship and not as tenants in common

        	 	 	 	 	 	 


  

  

  Additional abbreviations may also be used though not in the above list.

  
    

    
      


    

  

  For value received,                             hereby sells, assigns and transfers unto

  

  

  (PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER(S) OF ASSIGNEE(S))

  

  

  (PLEASE PRINT OR TYPEWRITE NAME(S) AND ADDRESS(ES), INCLUDING ZIP CODE, OF ASSIGNEE(S))

  

  

  Shares represented by the within Certificate, and does hereby irrevocably constitute and appoint                  Attorney to transfer the
    said shares on the books of the within named Company with full power of substitution in the premises.

  

  

  	
          Dated

        	 	 	 
	 	 	
          Shareholder

        
	 	 	 
	 	 	
          NOTICE: THE SIGNATURE(S) TO THIS ASSIGNMENT MUST CORRESPOND WITH THE NAME AS WRITTEN UPON THE FACE OF THE CERTIFICATE IN EVERY PARTICULAR, WITHOUT
            ALTERATION OR ENLARGEMENT OR ANY CHANGE WHATEVER.

        
	
          Signature(s) Guaranteed:

        	 	 
	 	 	 
	
          By

        	 	 
	 	 	 
	 	 	 
	 	 	 


  

  

  

  

  THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP
    IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM, PURSUANT TO S.E.C. RULE 17Ad-15 OR ANY SUCCESSOR RULE).

  

  

  In each case, as more fully described in the Company’s final prospectus dated                     , 2020, the holder(s) of this certificate shall be entitled to
    receive a pro-rata portion of certain funds held in the trust account established in connection with its initial public offering only in the event that (i) the Company redeems the Class A ordinary shares sold in its initial public offering and
    liquidates because it does not consummate an initial business combination within the period of time set forth in the Company’s amended and restated memorandum and articles of association, as the same may be amended from time to time, (ii) the Company
    redeems the Class A ordinary shares sold in its initial public offering in connection with a shareholder vote to amend the Company’s amended and restated memorandum and articles of association (A) to modify the substance or timing of the Company’s
    obligation to provide holders of the Class A ordinary shares the right to have their shares redeemed in connection with the Company’s initial business combination or to redeem 100% of the Class A ordinary shares if the Company does not complete its
    initial business combination within the time period set forth therein or (B) with respect to any other provision relating to the rights of holders of the Class A ordinary shares, or (iii) if the holder(s) seek(s) to redeem for cash his, her, its or
    their respective Class A ordinary shares in connection with a tender offer (or proxy solicitation, solely in the event the Company seeks shareholder approval of the proposed initial business combination) setting forth the details of a proposed initial
    business combination. In no other circumstances shall the holder(s) have any right or interest of any kind in or to the trust account.