U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 National Animal Disease Center: Ames, IA
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Research Units
                        Food Safety and Enteric PathogensSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home People & Locations







Tyler  Thacker
                        National Animal Disease Center

                        




                        
                        Deputy Director
                        Phone: (515) 337-7269
                        
                        
                        Fax: (515) 337-7428(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            **Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Potential for improved detection of bovine tuberculosis by targeting combined blood biomarkers in multi-test algorithms
                                                        

- (Peer Reviewed Journal)Sridhara, A.A., Johnathan-Lee, A., Elahi, R., Sikar-Gang, A., Lambotte, P., Esfandiari, J., De Juan, L., Gortazar, C., Jones, G., Vordermeier, H., Marpe, B.N., Thacker, T.C., Palmer, M.V., Waters, W., Lyachchenko, K.P. 2022. Potential for improved detection of bovine tuberculosis by targeting combined blood biomarkers in multi-test algorithms. Veterinary Immunology and Immunopathology. Volume 248, June 2022, 110419. https://doi.org/10.1016/j.vetimm.2022.110419.Use of blood matrices and alternative biological fluids for antibody detection in animal tuberculosis
                                                        

- (Peer Reviewed Journal)Lyaschcenko, K., Sikar-Gang, A., Sridhara, A., Johnathan-Lee, A., Elahi, R., Greenwald, R., Lambotte, P., Esfandiari, J., Roos, E., Kerry, T., Miller, M., Thacker, T.C., Palmer, M.V., Waters, W.R. 2021. Use of blood matrices and alternative biological fluids for antibody detection in animal tuberculosis. Veterinary Immunology and Immunopathology. 239.  Article 110303. https://doi.org/10.1016/j.vetimm.2021.110303.Severity of bovine tuberculosis is associated with innate immune-biased transcriptional signatures of whole blood in early weeks after experimental Mycobacterium bovis infection
                                                        

- (Peer Reviewed Journal)Wiarda, J.E., Boggiatto, P.M., Bayles, D.O., Waters, R.W., Thacker, T.C., Palmer, M.V. 2020. Severity of bovine tuberculosis is associated with innate immune-biased transcriptional signatures of whole blood in early weeks after experimental Mycobacterium bovis infection. PLoS ONE. 15(11). https://doi.org/10.1371/journal.pone.0239938.Mycobacterium bovis bacille Calmette-Guérin (BCG) results in positive tuberculin skin test results in a dose-dependent fashion in white-tailed deer (Odocoileus virginianus)
                                                        

- (Peer Reviewed Journal)Palmer, M.V., Waters, W.R., Thacker, T.C. 2020. Vaccination of white-tailed deer (Odocoileus virginianus) with Mycobacterium bovis bacille Calmette-Guérin (BCG) results in positive tuberculin skin test results in a dose-dependent fashion. Research in Veterinary Science. 129:70-73. https://doi.org/10.1016/j.rvsc.2020.01.010.Biomarkers of cell-mediated immunity to bovine tuberculosis

- (Peer Reviewed Journal)Characteristics of subclinical Mycobacterium avium subsp paratuberculosis infection in a captive white-tailed deer herd
                                                        

- (Peer Reviewed Journal)Palmer, M.V., Kanipe, C., Cox, R.J., Robbe Austerman, S., Thacker, T.C. 2019. Characteristics of subclinical Mycobacterium avium ssp. paratuberculosis infection in a captive white-tailed deer herd. Journal of Veterinary Diagnostic Investigation. 31(6):844-851. https://doi.org/10.1177/1040638719873028.Early pulmonary lesions in cattle infected via aerosolized Mycobacterium bovis
                                                        

- (Peer Reviewed Journal)Palmer, M.V., Wiarda, J.E., Kanipe, C., Thacker, T.C. 2019. Early pulmonary lesions in cattle infected via aerosolized Mycobacterium bovis. Veterinary Pathology. 56(4). https://doi.org/10.1177%2F0300985819833454.Use of the human vaccine, Mycobacterium bovis Bacillus Calmette Guerin in deer
                                                        

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C. 2018. Use of the human vaccine, Mycobacterium bovis Bacillus Calmette Guerin in deer. Frontiers in Veterinary Science. 5:244. https://doi.org/10.3389/fvets.2018.00244.Symposium review: Omics in dairy and animal science--Promise, potential, and pitfalls
                                                        

- (Peer Reviewed Journal)Lippolis, J.D., Powell, E.J., Reinhardt, T.A., Thacker, T.C., Casas, E. 2019. Symposium review: omics in dairy and animal science-promise, potential, and pitfalls. Journal of Dairy Science. 102(5):4741-4754. https://doi.org/10.3168/jds.2018-15267.Mistaken identity of a PCR target proposed for identification of Mycoplasma bovis and the effect of sequence variation on assay performance

- (Abstract Only)Mistaken identity of an open reading frame proposed for PCR-based identification of Mycoplasma bovis and the effect of polymorphisms and insertions on assay performance
                                                        

- (Peer Reviewed Journal)Register, K.B., Boatwright Jr, W.D., Gesy, K.M., Thacker, T.C., Jelinski, M.D. 2018. Mistaken identity of an open reading frame proposed for PCR-based identification of Mycoplasma bovis and the effect of polymorphisms and insertions on assay performance. Journal of Veterinary Diagnostic Investigation. 30(4):637-641. https://doi.org/10.1177/1040638718764799.Genomic and transcriptomic analysis of Escherichia coli strains associated with persistent and transient bovine mastitis and the role of colanic acid
                                                        

- (Peer Reviewed Journal)Lippolis, J.D., Holman, D.B., Brunelle, B.W., Thacker, T.C., Bearson, B.L., Reinhardt, T.A., Sacco, R.E., Casey, T. 2017. Genomic and transcriptomic analysis of Escherichia coli strains associated with persistent and transient bovine mastitis and the role of colanic acid. Infection and Immunity. 86(1):e00566-17. https://doi.org/10.1128/IAI.00566-17.Evaluation of tissue fixation methods to inactivate Mycobacterium bovis under routine laboratory conditions
                                                        

- (Peer Reviewed Journal)Thacker, T.C., Palmer, M.V., Waters, W.R. 2017. Evaluation of tissue fixation methods to inactivate Mycobacterium bovis under routine laboratory conditions. Applied Biosafety. 22(4):152-155. https://doi.org/10.1177%2F1535676017737315.Genome sequences of Escherichia coli strains that cause persistent and transient mastitis
                                                        

- (Peer Reviewed Journal)Thacker, T.C., Lippolis, J.D., Brunelle, B.W., Casey, T., Reinhardt, T.A., Sacco, R.E., Holman, D.B. 2017. Genome sequences of Escherichia coli strains that cause persistent and transient mastitis. Genome Announcements. 5(34):e00775-17. https://doi.org/10.1128/genomeA.00775-17.Using white-tailed deer (Odocoileus virginianus) in infectious disease research

- (Peer Reviewed Journal)Palmer, M.V., Cox, R.J., Waters, W.R., Thacker, T.C., Whipple, D.L. 2017. Using white-tailed deer (Odocoileus virginianus) in infectious disease research. Journal of the American Association for Laboratory Animal Science. doi: no_doi/1494535970305.Patterns and processes of Mycobacterium bovis evolution revealed by phylogenomic analyses

- (Peer Reviewed Journal)Patane, J.S., Martins, J., Castelao, A.B., Nishibe, C., Montera, L., Bigi, F., Zumarrago, M.J., Cataldi, A.A., Junior, A.F., Roxo, E., Osorio, A.L., Jorge, K.S., Thacker, T.C., De Almeia, F., Araujo, F.R., Setubal, J.C. 2017. Patterns and processes of Mycobacterium bovis evolution revealed by phylogenomic analyses. Genome Biology and Evolution. doi: 10.1093/gbe/evx022.Increased TNF-alpha/IFN-gamma/IL-2 and decreased TNF-alpha/IFN-gamma production by central memory T cells are associated with protective responses against bovine tuberculosis following BCG vaccination

- (Peer Reviewed Journal)Maggioli, M.F., Palmer, M.V., Thacker, T.C., Vordermeier, H.M., McGill, J.L., Whelan, A.O., Larsen, M.H., Waters, W.R. 2016. Increased TNF-alpha/IFN-gamma/IL-2 and decreased TNF-alpha/IFN-gamma production by central memory T cells are associated with protective responses against bovine tuberculosis following BCG vaccination. Frontiers in Immunology. 7:421.Comparative genomics of archived pyrazinamide resistant Mycobacterium tuberculosis complex isolates from Uganda

- (Abstract Only)Multinucleated giant cell cytokine expression in pulmonary granulomas of cattle experimentally infected with Mycobacterium bovis

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R. 2016. Multinucleated giant cell cytokine expression in pulmonary granulomas of cattle experimentally infected with Mycobacterium bovis. Veterinary Immunology and Immunopathology. 180:34-39.Evaluation of pathogen-specific biomarkers for the diagnosis of tuberculosis in white-tailed deer (Odocoileus virginianus)

- (Peer Reviewed Journal)Wanzala, S.I., Palmer, M.V., Waters, W.R., Thacker, T.C., Carstensen, M., Travis, D., Sreevatson, S. 2017. Evaluation of pathogen-specific biomarkers for the diagnosis of tuberculosis in white-tailed deer (Odocoileus virginianus). American Journal of Veterinary Research. 78(6):729-734. doi: 10.2460/ajvr.78.6.729.Polymorphisms of twenty regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis

- (Peer Reviewed Journal)Bigi, M.M., Blaco, F.C., Araujo, F.R., Thacker, T.C., Zumarraga, M.J., Cataldi, A.A., Soria, M.A., Bigi, F. 2016. Polymorphisms of twenty regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis. Microbiology and Immunology. 60:552-560 doi: 10.1111/1348-0421.12402.Differential gene expression of three mastitis-causing Escherichia coli strains grown under planktonic, swimming, and swarming culture conditions
                                                        

- (Peer Reviewed Journal)Lippolis, J.D., Brunelle, B.W., Reinhardt, T.A., Sacco, R.E., Thacker, T.C., Looft, T.P., Casey, T. 2016. Differential gene expression of three mastitis-causing Escherichia coli strains grown under planktonic, swimming, and swarming culture conditions. mSystems. 1(4):e00064-16.Screening of microbial volatile organic compounds for detection of disease in cattle: development of lab-scale method

- (Abstract Only)Mauer, D., Ellis, C., Thacker, T.C., Rice, S., Koziel, J. 2016. Screening of microbial volatile organic compounds for detection of disease in cattle: development of lab-scale method. Meeting Abstract. page 74.Vaccination of white-tailed deer (Odocoileus virginianus) for protection against bovine tuberculosis

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Robbe-Austerman, S., Dressel, D., Vercauteren, K., Lavelle, M., Campa, H., Nol, P. 2016. Vaccination of white-tailed deer (Odocoileus virginianus) for protection against bovine tuberculosis. Meeting Abstract. doi: 10.1016/j.vaccine.2007.06.056 1(1):200.Polyfunctional cytokine production by central memory T cells from cattle in response to Mycobacterium bovis infection and BCG vaccination

- (Abstract Only)Maggioli, M.F., Palmer, M.V., Thacker, T.C., Vordemeier, H.M., Mcgill, J.L., Larsen, M.H., Waters, W.R. 2016. Polyfunctional cytokine production by central memory T cells from cattle in response to Mycobacterium bovis infection and BCG vaccination. American Association of Immunologists Proceedings. page 33.Interleukin-17A as a biomarker for bovine tuberculosis

- (Peer Reviewed Journal)Waters, W.R., Maggioli, M.F., Palmer, M.V., Thacker, T.C., McGill, J.L., Vordermeier, M., Berney-Meyers, L., Jacobs Jr., W.R., Larsen, M.H. 2015. Interleukin-17A as a biomarker for bovine tuberculosis. Clinical and Vaccine Immunology. 23(2):168-80. doi: 10.1128/CVI.00637-15.Differential cytokine gene expression in granulomas from lungs and lymph nodes of cattle experimentally infected with aerosolized Mycobacterium bovis

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R. 2015. Differential cytokine gene expression in granulomas from lungs and lymph nodes of cattle experimentally infected with aerosolized Mycobacterium bovis. PLoS One. 10(12):e0142287.Polyfunctional cytokine production by central memory T cells from cattle in response to Mycobacterium bovis infection and BCG vaccination

- (Abstract Only)Maggioli, M.F., Palmer, M.V., Thacker, T.C., Vordermeier, M., Mcgill, J., Larsen, M., Jacobs, W., Waters, W.R. 2015. Polyfunctional cytokine production by central memory T cells from cattle in response to Mycobacterium bovis infection and BCG vaccination. Meeting Abstract. page 33.Anatomical distribution of Mycobacterium bovis genotypes in experimentally infected white-tailed deer

- (Peer Reviewed Journal)Thacker, T.C., Palmer, M.V., Robbe-Austerman, S., Stuber, T.P., Waters, W.R. 2015. Anatomical distribution of Mycobacterium bovis genotypes in experimentally infected white-tailed deer. Veterinary Microbiology. 180(1-2):75-81.doi: 10.1016/j.vetmic.2015.07.006.Analysis of cytokine mRNA expression using a novel chromogenic in situ hybridization method in pulmonary granulomas of cattle experimentally infected by aerosolized Mycobacterium bovis

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R. 2015. Analysis of cytokine mRNA expression using a novel chromogenic in situ hybridization method in pulmonary granulomas of cattle experimentally infected by aerosolized Mycobacterium bovis. Journal of Comparative Pathology. 153(2-3):150-159.The effects of serial skin testing with purified protein derivative on the level and quality of antibodies to complex and defined antigens in Mycobacterium bovis-infected cattle
                                                        

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Stafne, M.R., Bass, K.E., Maggioli, M., Thacker, T.C., Linscott, R., Lawrence, J.C., Nelson, J.T., Esfandiari, J., Greenwald, R., Lyashchenko, K.P. 2015. The effects of serial skin testing with purified protein derivative on the level and quality of antibodies to complex and defined antigens in Mycobacterium bovis-infected cattle. Clinical and Vaccine Immunology. 22(6):641-649.Characterization of effector and memory T cell subsets in the immune response to bovine tuberculosis in cattle
                                                        

- (Peer Reviewed Journal)Maggioli, M.F., Palmer, M.V., Thacker, T.C., Vordermeier, H.M., Waters, W.R. 2015. Characterization of effector and memory T cell subsets in the immune response to bovine tuberculosis in cattle. PLoS One. 10(4):e0122571.In situ cytokine expression in pulmonary granulomas of cattle experimentally infected by aerosolized Mycobacterium bovis

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C. 2015. In situ cytokine expression in pulmonary granulomas of cattle experimentally infected by aerosolized Mycobacterium bovis [abstract]. In Proceedings of the Keystone Symposium; Granulomas in Infectious and Non-infectious Diseases, January 22-27, 2015, Santa Fe, New Mexico. p. 141.Effect of skin test on serum antibody responses to Mycobacterium bovis infection in cattle

- (Abstract Only)Waters, W.R., Nelson, J., Thacker, T.C., Maggioli, M., Stafne, M., Bass, K., Linscott, R., Lawrence, J., Palmer, M.V. 2014. Effect of skin test on serum antibody responses to Mycobacterium bovis infection in cattle [abstract]. United States Animal Health Association. Abstract No. 22.Mannosylated Lipoarabinomannan in serum as a biomarker candidate for subclinical bovine tuberculosis

- (Peer Reviewed Journal)Lamont, E.A., Ribeiro-Lima, J., Waters, W.R., Thacker, T.C., Sreevatsan, S. 2014. Mannosylated Lipoarabinomannan in serum as a biomarker candidate for subclinical bovine tuberculosis. BMC Research Notes. 7:559.Virulence of two strains of Mycobacterium bovis in cattle following aerosol infection

- (Peer Reviewed Journal)Waters, W.R., Thacker, T.C., Nelson, J.T., DiCarlo, D.M., Maggioli, M.F., Greenwald, R., Esfandiari, J., Lyashchenko, K.P., Palmer, M.V. 2014. Virulence of two strains of Mycobacterium bovis in cattle following aerosol infection. Journal of Comparative Pathology. 151(4):410-419.Oral vaccination of white-tailed deer (Odocoileus virginianus) with Mycobacterium bovis Bacillus Calmette-Guerin (BCG)
                                                        

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R., Robbe-Austerman, S. 2014. Oral vaccination of white-tailed deer (Odocoileus virginianus) with Mycobacterium bovis Bacillus Calmette-Guerin (BCG). PLoS One. 9(5):e97031.Circulating Mycobacterium bovis peptides and host response proteins as biomarkers for unambiguous detection of subclinical infection
                                                        

- (Peer Reviewed Journal)Lamont, E.A., Janagama, H.K., Ribeiro-Lima, J., Hart, L., Seth, M., Yang, M., Kumi, K., Waters, W.R., Thacker, T.C., Harris, N.B., Sreevatsan, S. 2014. Circulating Mycobacterium bovis peptides and host response proteins as biomarkers for unambiguous detection of subclinical infection. Journal of Clinical Microbiology. 52(2):536-543.Clinical and diagnostic developments of a gamma interferon release assay for use in bovine tuberculosis control programs
                                                        

- (Peer Reviewed Journal)Bass, K.E., Nonnecke, B.J., Palmer, M.V., Thacker, T.C., Hardegger, R., Schroeder, B., Raeber, A.J., Waters, W.R. 2013. Clinical and diagnostic developments of a gamma interferon release assay for use in bovine tuberculosis control programs. Clinical and Vaccine Immunology. 20(12):1827-1835.Testing a molasses-based bait for oral vaccination of white-tailed deer (Odocoileus virginianus) against Mycobacterium bovis
                                                        

- (Peer Reviewed Journal)Palmer, M.V., Stafne, M.R., Waters, W.R., Thacker, T.C., Phillips, G.E. 2013. Testing a molasses-based bait for oral vaccination of white-tailed deer (Odocoileus virginianus) against Mycobacterium bovis. European Journal of Wildlife Research. 60:265-270.Isolation of Mycobacteria from clinical samples collected in the United States from 2004 to 2011

- (Peer Reviewed Journal)Thacker, T.C., Robbe-Austerman, S., Harris, B., Palmer, M.V., Waters, W.R. 2013. Isolation of Mycobacteria from clinical samples collected in the United States from 2004 to 2011. BioMed Central (BMC) Veterinary Research. 9(1):100.Active and latent ovine Herpesvirus-2 (OvHV-2) infection in a herd of captive white-tailed deer (Odocoileus virginianus)

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Madison, R.J., Koster, L., Swenson, S., Li, H. 2013. Active and latent ovine Herpesvirus-2 (OvHV-2) infection in a herd of captive white-tailed deer (Odocoileus virginianus). Journal of Comparative Pathology. 149(2-3):162-166.Persistence of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Danish in White-tailed deer (Odocoileus virginianus) vaccinated with a lipid-formulated oral vaccine

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R., Robbe-Austerman, S., Aldwell, F.E. 2012. Persistence of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Danish in White-tailed deer (Odocoileus virginianus) vaccinated with a lipid-formulated oral vaccine. Transboundary and Emerging Diseases. DOI.org/10.1111/tbed.12032.Single nucleotide polymorphisms in the Mycobacterium bovis genome resolve phylogenetic relationships

- (Peer Reviewed Journal)Joshi, D., Harris, B., Waters, W.R., Thacker, T.C., Mathema, B., Krieswirth, B., Sreevatsan, S. 2012. Single nucleotide polymorphisms in the Mycobacterium bovis genome resolve phylogenetic relationships. Journal of Clinical Microbiology. 50(12):3853-3861.Mycobacterium bovis:  a model pathogen at the interface of domestic livestock, wildlife, and humans

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R., Gortazar, C., Corner, L.A. 2012. Mycobacterium bovis:  a model pathogen at the interface of domestic livestock, wildlife, and humans. Veterinary Medicine International [serial online]. 2012:Article ID 236205. Available: http://www.hindawi.com/journals/vmi/2012/236205/.Evaluation of gamma interferon (IFN-gamma)-induced protein 10 (IP-10) responses for detection of cattle infected with Mycobacterium bovis: comparisons to IFN-gamma responses

- (Peer Reviewed Journal)Waters, W.R., Thacker, T.C., Nonnecke, B.J., Palmer, M.V., Schiller, I., Oesch, B., Vordermeier, H.M., Silva, E., Estes, D.M. 2012. Evaluation of gamma interferon (IFN-gamma)-induced protein 10 responses for detection of cattle infected with Mycobacterium bovis: comparisons to IFN-gamma responses. Clinical and Vaccine Immunology. 19(3):346-351.Transcriptome analysis of stimulated PBMC from Mycobacterium bovis infected cattle

- (Abstract Only)Thacker, T.C., Palmer, M.V., Waters, W.R. 2011. Transcriptome analysis of stimulated PBMC from Mycobacterium bovis infected cattle [abstract]. 4th International Symposium on Animal Functional Genomics. p. 28.Enterohemorrhagic Escherichia coli O157:H7 requires quorum sensing transcriptional regulators QseA and SdiA for colonization and persistence in the bovine intestinal tract

- (Abstract Only)Sharma, V.K., Bearson, S.M., Thacker, T.C. 2011. Enterohemorrhagic Escherichia coli O157:H7 requires quorum sensing transcriptional regulators QseA and SdiA for colonization and persistence in the bovine intestinal tract [abstract]. 71st Annual Meeting of the North Central Branch of the American Society for Microbiology. October 7-8, 2011, Des Moines, Iowa. 59:147.Development and evaluation of an enzyme-linked immunosorbent assay for use in the detection bovine tuberculosis in cattle

- (Peer Reviewed Journal)Waters, W.R., Buddle, B.M., Vordermeier, H.M., Gormley, E., Palmer, M.V., Thacker, T.C., Bannantine, J.P., Stabel, J.R., Linscott, R., Martel, E., Milian, F., Foshaug, W., Lawrence, J.C. 2011. Development and evaluation of an enzyme-linked immunosorbent assay for use in the detection of bovine tuberculosis in cattle. Clinical and Vaccine Immunology. 18(11):1882-1888.Improved Specificity for Detection of Mycobacterium bovis in Fresh Tissues Using IS6110 Real-time PCR

- (Peer Reviewed Journal)Thacker, T.C., Harris, B., Palmer, M.V., Waters, W.R. 2011. Improved specificity for detection of Mycobacterium bovis in fresh tissues using IS6110 real-time PCR. BioMed Central (BMC) Veterinary Research [serial online]. 7(50). Available: http://www.biomedcentral.com/1746-6148/7/50.Tuberculosis in domestic livestock:  pathogenesis, transmission, and vaccination

- (Proceedings)Palmer, M.V., Thacker, T.C., Waters, W.R. 2011. Tuberculosis in domestic livestock:  pathogenesis, transmission, and vaccination. In: Proceedings of the 2011 American College of Veterinary Pathologists, December 3-7, 2011, Nashville, Tennessee. 2011 CDROM.Comparison of peptide cocktails and purified protein derivatives for use in the Bovigam assay

- (Abstract Only)Bass, K.E., Nonnecke, B.J., Palmer, M.V., Thacker, T.C., Hardegger, R., Schroeder, B., Raeber, A.J., Waters, W.R. 2011. Comparison of peptide cocktails and purified protein derivatives for use in the Bovigam assay [abstract]. American Society of Veterinary Laboratory Diagnosticians. p. 186.Examination of the reticular epithelium of the bovine pharyngeal tonsil

- (Peer Reviewed Journal)Palmer, M.V., Stasko, J.A., Waters, W.R., Thacker, T.C. 2011. Examination of the reticular epithelium of the bovine pharyngeal tonsil. The Anatomical Record. 294(11):1939-1950.Resolution of M. bovis phylogeny using genome-wide single nucleotide polymorphisms

- (Abstract Only)Joshi, D., Waters, W.R., Harris, B., Thacker, T.C., Palmer, M.V., Mathema, B., Krieswirth, B., Sreevatsan, S. 2011. Resolution of M. bovis phylogeny using genome-wide single nucleotide polymorphisms [abstract]. American Society for Microbiology. Abstract No. 1496.A Leptospira borgpetersenii Serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization

- (Peer Reviewed Journal)Zuerner, R.L., Alt, D.P., Palmer, M.V., Thacker, T.C., Olsen, S.C. 2011. A Leptospira borgpetersenii Serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization. Clinical and Vaccine Immunology. 18(4):684-691.Bovine tuberculosis:  Immune response and vaccine efficacy studies

- (Proceedings)Waters, W.R., Palmer, M.V., Thacker, T.C. 2010. Bovine tuberculosis:  Immune response and vaccine efficacy studies. Proceedings of the Conference of Research Workers in Animal Diseases. p. 18.Update on vaccination of white-tailed deer with Mycobacterium bovis BCG:  Safety and Efficacy

- (Abstract Only)Palmer, M.V., Thacker, T.C., Waters, W.R. 2010. Update on vaccination of white-tailed deer with Mycobacterium bovis BCG:  Safety and Efficacy [abstract]. American Association of Veterinary Laboratory Diagnosticians. p. 122.Boving Tuberculosis:  Immune Response and Vaccine Efficacy Studies

- (Abstract Only)Waters, W.R., Palmer, M.V., Thacker, T.C. 2010. Boving Tuberculosis:  Immune Response and Vaccine Efficacy Studies [abstract]. Conference of Research Workers in Animal Diseases. Abstract No. 22.Bovine Tuberculosis Vaccine Efficacy Studies:  Neonatal Calves and White-tailed Deer

- (Abstract Only)Waters, W.R., Palmer, M.V., Thacker, T.C. 2010. Bovine Tuberculosis Vaccine Efficacy Studies:  Neonatal Calves and White-tailed Deer [abstract]. American College of Veterinary Pathologists/American Society for Veterinary Clinical Pathology. p. 89.Tuberculosis immunity:  Opportunities from studies with cattle

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Thacker, T.C., Davis, W.C., Sreevatsan, S., Coussens, P., Meade, K.G., Hope, J.C., Estes, D.M. 2010. Tuberculosis immunity:  Opportunities from studies with cattle. Clinical and Developmental Immunology. 2011:01-11.Investigations on Deer to Deer and Deer to Cattle Transmission of the Vaccine Mycobacterium bovis bacillus Calmette-Guerin (BCG)

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R., Robbe-Austerman, S., Harris, B.N. 2010. Investigations on deer to deer and deer to cattle transmission of the vaccine Mycobacterium bovis Bacillus Calmette-Guerin (BCG). Journal of Vaccines and Vaccination [serial online]. 1:104. Available: http://www.omicsonline.org/2157-7560/2157-7560-1-104.pdf.Granulysin as a Correlate of Immune Response following Mycobacterial Infection

- (Abstract Only)Calderon, V.E., Silva, E., Santos, L., Waters, W.R., Palmer, M.V., Thacker, T.C., Jacobs, W.R., Larsen, M.H., Vilcheze, C., Estes, D.M. 2010. Granulysin as a Correlate of Immune Response following Mycobacterial Infection [abstract].Comparative Analysis of the Bovigam Interferon-Gamma Elisa for Bovine Tuberculosis Using Alternative Antigens or Tuberculins for Blood Stimulation in Field Trials and Experimental Infections

- (Abstract Only)Schroder, B., Hardegger, R., Purro, M., Moyen, J., Gormley, E., Waters, W.R., Palmer, M.V., Thacker, T.C., Whelan, A., Vordermeier, H.M., Raeber, A.J. 2010. Comparative Analysis of the Bovigam Interferon-Gamma Elisa for Bovine Tuberculosis Using Alternative Antigens or Tuberculins for Blood Stimulation in Field Trials and Experimental Infections [abstract].Bovine Tuberculosis: A Review of Current and Emerging Diagnostic Techniques in View of their Relevance for Disease Control and Eradication

- (Peer Reviewed Journal)Schiller, I., Oesch, B., Vordermeier, H.M., Palmer, M.V., Harris, B.N., Orloski, K.A., Buddle, B.M., Thacker, T.C., Lyashchenko, K.P., Waters, W.R. 2010. Bovine tuberculosis: a review of current and emerging diagnostic techniques in view of their relevance for disease control and eradication. Transboundary and Emerging Diseases. 57(4):205-220.Bovine tuberculosis in Europe from the perspective of an officially tuberculosis free country: Trade, surveillance, and diagnostics

- (Peer Reviewed Journal)Schiller, I., Waters, W.R., Vordermeier, H.M., Thomas, J., Welsh, M., Keck, N., Whelan, A., Gormley, E., Boschiroli, M.L., Moyen, J.L., Vela, C., Cagiola, M., Buddle, B.M., Palmer, M.V., Thacker, T.C., Oesch, B. 2011. Bovine tuberculosis in Europe from the perspective of an officially tuberculosis free country: Trade, surveillance, and diagnostics. Veterinary Microbiology. 151(1-2):153-159.Persistence of Mycobacterium bovis Bacillus Calmette-Guerin (BCG) in White-tailed Deer (Odocoileus virginianus) After Oral or Parenteral Vaccination

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R., Robbe-Austerman, S., Semakaleng, L., Harris, N.B. 2010. Persistence of Mycobacterium bovis Bacillus Calmette-Guerin (BCG) in White-tailed Deer (Odocoileus virginianus) after oral or parenteral vaccination. Zoonoses and Public Health. 57(7-8):e206-e212.Bovine Tuberculosis:  Effect of the Tuberculin Skin Test on In vitro Interferon gamma Responses

- (Peer Reviewed Journal)Schiller, I., Vordermeier, H.M., Waters, W.R., Whelan, A.O., Coad, M., Gormley, E., Buddle, B.M., Palmer, M.V., Thacker, T.C., Mcnair, J., Welsh, M., Hewinson, R.G., Oesch, B. 2010. Bovine Tuberculosis:  Effect of the Tuberculin Skin Test on In vitro Interferon gamma Responses. Veterinary Immunology and Immunopathology. 136(1-2):1-11.Modulation of the Bovine Innate Immune Response by Production of 1alpha,25-Dihydroxyvitamin D3 in Bovine Monocytes

- (Peer Reviewed Journal)Nelson, C.D., Reinhardt, T.A., Thacker, T.C., Beitz, D.C., Lippolis, J.D. 2010. Modulation of the Bovine Innate Immune Response by Production of 1alpha,25-Dihydroxyvitamin D3 in Bovine Monocytes. Journal of Dairy Science. 93(3):1041-1049.Evaluation of a Second Generation BOVIGAM Interferon Gamma (IFN-gamma) Assay with Alternative Antigens for Stimulation of Whole Blood Cultures

- (Abstract Only)Hardegger, R., Purro, M., Schroder, B., Moyen, J.L., Gormley, E., Waters, W.R., Palmer, M.V., Thacker, T.C., Vordermeier, H.M., Raeber, A.J. 2009. Evaluation of a Second Generation BOVIGAM Interferon Gamma (IFN-gamma) Assay with Alternative Antigens for Stimulation of Whole Blood Cultures [abstract].Update on Comparative Studies for Diagnosis of Bovine Tuberculosis Using The Interferon Gamma (IFN-gamma) Assay with Tuberculins or Alternative Antigens for Whole Blood Stimulation

- (Abstract Only)Schroder, B., Hardegger, R., Moyen, J.L., Gormley, E., Waters, W.R., Palmer, M.V., Thacker, T.C., Nonnecke, B.J., Keck, N., Egnuni, T., Whelan, A., Vordermeier, H.M., Raeber, A.J. 2009. Update on Comparative Studies for Diagnosis of Bovine Tuberculosis Using The Interferon Gamma (IFN-gamma) Assay with Tuberculins or Alternative Antigens for Whole Blood Stimulation [abstract].Improvements to the BOVIGAM Interferon Gamma (IFN-gamma) Assay for use with Alternative Antigens as Stimulants of Whole Blood Cultures

- (Abstract Only)Hardegger, R., Purro, M., Schroder, B., Moyen, J.L., Gormley, E., Waters, W.R., Palmer, M.V., Thacker, T.C., Whelan, A., Vordermeier, H.M., Raeber, A.J. 2009. Improvements to the BOVIGAM Interferon Gamma (IFN-gamma) Assay for use with Alternative Antigens as Stimulants of Whole Blood Cultures [abstract].Comparison of Tuberculin Activity in the Interferon-gamma Assay for the Diagnosis of Bovine Tuberculosis

- (Abstract Only)Schiller, I., Schroder, B., Vordermeier, H.M., Waters, W.R., Palmer, M.V., Thacker, T.C., Whelan, A., Hardegger, R., Marg-Haufe, B., Raeber, A., Oesch, B. 2009. Comparison of Tuberculin Activity in the Interferon-gamma Assay for the Diagnosis of Bovine Tuberculosis [abstract].Assessment of OmpATb as a Novel Antigen for the Diagnosis of Bovine Tuberculosis

- (Abstract Only)Schiller, I., Schroder, B., Vordermeier, H.M., Waters, W.R., Palmer, M.V., Thacker, T.C., Whelan, A., Hardegger, R., Marg-Haufe, B., Raeber, A., Oesch, B. 2009. Assessment of OmpATb as a Novel Antigen for the Diagnosis of Bovine Tuberculosis [abstract].Improved Performance of the Interferon Gamma (IFN-gamma) Assay with Alternative Antigens for Stimulation of Whole Blood

- (Abstract Only)Schroder, B., Hardegger, R., Marg-Haufe, B., Schiller, I., Moyen, J.L., Waters, W.R., Palmer, M.V., Thacker, T.C., Stamm, C., Nonnecke, B.J., Keck, N., Egnuni, T., Whelan, A., Sigafoose, T., Welsh, M., Cagiola, M., Gordon, S., Meijlis, J., Carter, C., Vordermeier, H.M., Raeber, A.J. 2009. Improved Performance of the Interferon Gamma (IFN-gamma) Assay with Alternative Antigens for Stimulation of Whole Blood [abstract].Innate and Adaptive Cytotoxic Lymphocytes and Prognostic Markers of Host Responses to Bovine TB

- (Abstract Only)Estes, D.M., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Jacobs Jr., W.R., Larsen, M.H., Endsley, J.J., Hogg, A., Shell, E., Mcalauy, M., Capinos-Scherer, C.F., Coffey, T., Howard, C.J., Villareal-Ramos, B., Waters, W.R. 2009. Innate and Adaptive Cytotoxic Lymphocytes and Prognostic Markers of Host Responses to Bovine TB [abstract].Bovine Tuberculosis in Europe From the Perspective of an OTF Country:  Trade, Surveillance and Diagnostics

- (Abstract Only)Schiller, I., Waters, W.R., Vordermeier, H.M., Jemmi, T., Welsh, M., Keck, N., Whelan, A., Gormley, E., Boschiroli, M.L., Moyen, J.L., Vela, C., Cagiola, M., Buddle, B., Palmer, M.V., Thacker, T.C., Oesch, B. 2009. Bovine Tuberculosis in Europe From the Perspective of an OTF Country:  Trade, Surveillance and Diagnostics [abstract].Cytokine Responses of Cattle to Experimental M. bovis Infection

- (Abstract Only)Development of a Second Generation Bovigam Interferon Gamma (IFN-gamma) Assay

- (Abstract Only)Hardegger, R., Purro, M., Schroder, B., Moyen, J.L., Gormley, E., Waters, W.R., Palmer, M.V., Thacker, T.C., Whelan, A., Vordermeier, H.M., Raeber, A.J. 2009. Development of a Second Generation Bovigam Interferon Gamma (IFN-gamma) Assay [abstract].Shared Feed as a Means of Deer to Deer and Deer to Cattle Transmission of Mycobacterium bovis

- (Abstract Only)Palmer, M.V., Thacker, T.C., Waters, W.R. 2009. Shared Feed as a Means of Deer to Deer and Deer to Cattle Transmission of Mycobacterium bovis [abstract]. Minnesota Bovine Tuberculosis Stakeholders Conference. p. 100.Single-Antigen Serological Testing for Bovine Tuberculosis

- (Peer Reviewed Journal)Green, L.R., Jones, C.C., Sherwood, A., Garkavi, I., Cangelosi, G.A., Thacker, T.C., Palmer, M.V., Waters, W.R., Rathe, C. 2009. Single-Antigen Serological Testing for Bovine Tuberculosis. Clinical and Vaccine Immunology. 16(9):1309-1313.Assessment of Mycobacterium tuberculosis OmpATb as a Novel Antigen for the Diagnosis of Bovine Tuberculosis

- (Peer Reviewed Journal)Schiller, I., Vordermeier, M., Waters, W.R., Palmer, M.V., Thacker, T.C., Whelan, A., Hardegger, R., Raeber, A., Oesch, B. 2009. Assessment of Mycobacterium tuberculosis OmpATb as a Novel Antigen for the Diagnosis of Bovine Tuberculosis. Clinical and Vaccine Immunology. 16(9):1314-1321.Signal Regulatory Protein alpha (SIRPalpha)+ Cells in the Adaptive Response to ESAT-6/CFP-10 Protein of Tuberculous Mycobacteria

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Estes, D.M., Larsen, M.H., Jacobs, W.R., Andersen, P., Mcnair, J., Minion, F.C., Lyashchenko, K.P., Hewinson, R.G., Vordermeier, H.M., Sacco, R.E. 2009. Signal Regulatory Protein alpha (SIRPalpha)+ Cells in the Adaptive Response to ESAT-6/CFP-10 Protein of Tuberculous Mycobacteria. PLoS One [serial online]. 4(7):e6414. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0006414.Optimization of a Whole-Blood Gamma Interferon Assay for Detection of Mycobacterium bovis-Infected Cattle

- (Peer Reviewed Journal)Schiller, I., Waters, W.R., Vordermeier, H.M., Nonnecke, B.J., Welsh, M., Keck, N., Whelan, A., Sigafoose, T., Stamm, C., Palmer, M.V., Thacker, T.C., Hardegger, R., Marg-Haufe, B., Raeber, A., Oesch, B. 2009. Optimization of a Whole-Blood Gamma Interferon Assay for Detection of Mycobacterium bovis-Infected Cattle. Clinical and Vaccine Immunology. 16(8):1196-1202.Comparison of Tuberculin Activity in the Interferon-gamma Assay for the Diagnosis of Bovine Tuberculosis

- (Peer Reviewed Journal)Schiller, I., Vordermeier, H.M., Waters, W.R., Kyburz, A., Cagiola, M., Whelan, A., Palmer, M.V., Thacker, T.C., Meijlis, J., Carter, C., Egnuni, T., Hardegger, R., Marg-Hauffe, B., Raeber, A., Oesch, B. 2010. Comparison of Tuberculin Activity in the Interferon-gamma Assay for the Diagnosis of Bovine Tuberculosis. Veterinary Record. 167(9):322-326.T-cell mRNA Expression in Response to Mycobacterium bovis BCG Vaccination and Mycobacterium bovis Infection of White-tailed deer

- (Peer Reviewed Journal)Thacker, T.C., Palmer, M.V., Waters, W.R. 2009. T-cell mRNA Expression in Response to Mycobacterium bovis BCG Vaccination and Mycobacterium bovis Infection of White-tailed deer. Clinical and Vaccine Immunology. 16(8):1139-1145.Viral Booster Vaccines Improve Mycobacterium bovis BCG-Induced Protection Against Bovine Tuberculosis

- (Peer Reviewed Journal)Vordermeier, H.M., Villarreal-Ramos, B., Cockle, P.J., Macaulay, M., Rhodes, S.G., Thacker, T.C., Gilbert, S.C., Mcshane, H., Hill, A.V., Xing, R.Z., Hewinson, R.G. 2009. Viral Booster Vaccines Improve Mycobacterium bovis BCG-Induced Protection Against Bovine Tuberculosis. Infection and Immunity. 77(8):3364-3373.Humoral Immune Responses of White-tailed Deer (Odocoileus virginianus) to Mycobacterium bovis BCG Vaccination and Experimental Challenge with M. bovis

- (Peer Reviewed Journal)Nol, P., Lyashchenko, K.P., Greenwald, R., Esfandiari, J., Waters, W.R., Palmer, M.V., Nonnecke, B.J., Keefe, T.J., Thacker, T.C., Rhyan, J.C., Aldwell, F.E., Salman, M.D. 2009. Humoral Immune Responses of White-tailed Deer (Odocoileus virginianus) to Mycobacterium bovis BCG Vaccination and Experimental Challenge with M. bovis. Clinical and Vaccine Immunology. 16(3):323-329.Efficacy and Immunogenicity of Mycobacterium bovis Delta RD1 against Aerosol M. bovis Infection in Neonatal Calves

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Capinos Scherer, C.F., Estes, D.M., Hewinson, R.G., Vordermeier, H.M., Barnes, S.W., Federe, G.C., Walker, J.R., Glynne, R.J., Hsu, T., Weinrick, B., Biermann, K., Larsen, M.H., Jacobs, W.R. 2009. Efficacy and Immunogenicity of Mycobacterium bovis Delta RD1 against Aerosol M. bovis Infection in Neonatal Calves. Vaccine. 27(8):1201-1209.The Calf Model of Immunity for Development of a Vaccine Against Tuberculosis

- (Review Article)Endsley, J., Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Jacobs, W.R., Larsen, M., Hogg, A., Shell, L., Mcalauy, M., Capinos-Scherer, C., Coffey, T., Howard, C., Villareal-Ramos, B., Estes, M. 2009. The Calf Model of Immunity for Development of a Vaccine Against Tuberculosis. Veterinary Immunology and Immunopathology. 128(1-3):199-204.Histology, Immunohistochemistry and Ultrastructure of the Bovine Palatine Tonsil with Special Emphasis on Reticular Epithelium

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R. 2009. Histology, Immunohistochemistry and Ultrastructure of the Bovine Palatine Tonsil with Special Emphasis on Reticular Epithelium. Veterinary Immunology and Immunopathology. 127(3-4):277-285.Interferon Gamma Assay for the Diagnosis of Bovine Tuberculosis

- (Abstract Only)Schiller, I., Marg-Haufe, B., Vordermeier, M., Waters, W.R., Whelan, A., Welsh, M., Keck, N., Moyen, J.L., Palmer, M.V., Thacker, T.C., Raeber, A., Oesch, B. 2008. Interferon Gamma Assay for the Diagnosis of Bovine Tuberculosis [abstract]. Paper No. 25.Vaccination with Mycobacterium bovis BCG Strains Danish and Pasteur in White-tailed Deer (Odocoileus virginianus) Experimentally Challenged with Mycobacterium bovis

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R. 2009. Vaccination with Mycobacterium bovis BCG Strains Danish and Pasteur in White-tailed Deer (Odocoileus virginianus) Experimentally Challenged with Mycobacterium bovis. Zoonoses and Public Health. 56(5):243-251.Tuberculosis Diagnosis:  Relevancy of Veterinary Applications to Human Disease

- (Abstract Only)Waters, W.R., Palmer, M.V., Thacker, T.C., Nonnecke, B.J., Lyashchenko, K., Schiller, I., Marg, B., Oesch, B., Vordermeier, M., O'Brien, D., Schmitt, S., Estes, M. 2008. Tuberculosis Diagnosis:  Relevancy of Veterinary Applications to Human Disease [abstract]. p. 17.Serum 25-Hydroxvitamin D Concentrations in Captive and Free-Ranging, White-Tailed Deer (Odocoileus virginianus)

- (Peer Reviewed Journal)Waters, W.R., Nonnecke, B.J., Gibbs, S.E., Yabsley, M.J., Schmitt, S.M., Cosgrove, M.K., Palmer, M.V., Thacker, T.C., Olsen, S.C., Horst, R.L., Reinhardt, T.A. 2009. Serum 25-Hydroxvitamin D Concentrations in Captive and Free-Ranging, White-Tailed Deer (Odocoileus virginianus). International Journal for Vitamin and Nutrition Research. 79(3):180-187.Tuberculosis Diagnosis:  Assay Optimization, Validation, and Antigens for Specific Diagnosis

- (Abstract Only)Waters, W.R., Palmer, M.V., Thacker, T.C., Nonnecke, B.J., Lyashchenko, K., Schiller, I., Marg, B., Oesch, B., Vordermeier, M., O'Brien, D., Schmitt, S., Estes, M. 2008. Tuberculosis Diagnosis:  Assay Optimization, Validation, and Antigens for Specific Diagnosis. [abstract].Vaccination of White-tailed Deer with Mycobacterium bovis Bacillus Calmette Guerin (BCG)

- (Proceedings)Thacker, T.C., Palmer, M.V., Waters, W.R. 2007. Vaccination of White-tailed Deer with Mycobacterium bovis Bacillus Calmette Guerin (BCG). In: Proccedings of the 42nd United States-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health, December 5-7, 2007, Tsukuba, Japan.CAMPYLOBACTER ECOLOGY IN THE TURKEY INTESTINE: SETTING THE STAGE FOR DEVELOPMENT OF PROTECTIVE PROBIOTICS

- (Abstract Only)Scupham, A.J., Wesley, I.V., Thacker, T.C. 2007. Campylobacter ecology in the turkey intestine: setting the stage for development of protective probiotics [abstract]. 42nd United States - Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. p.7.Vaccination of White-tailed deer (Odocoileus virginianus) with Mycobacterium bovis BCG

- (Abstract Only)Palmer, M.V., Thacker, T.C., Nol, P., Waters, W.R. 2007. Vaccination of White-tailed deer (Odocoileus virginianus) with Mycobacterium bovis BCG [abstract]. 111th Annual Meeting of the United States Animal Health Association. p. 35.Improved Specificity for Detection of Mycobacterium bovis in Fresh Tissue Using IS6110 Real-Time PCR

- (Abstract Only)Thacker, T.C., Harris, B., Palmer, M.V., Waters, W.R. 2007. Improved Specificity for Detection of Mycobacterium bovis in Fresh Tissue Using IS6110 Real-Time PCR [abstract].Failure of a Mycobacterium tuberculosis DeltaRD1 DeltapanCD Double Deletion Mutant in a Neonatal Calf Aerosol M. bovis Challenge model: Comparisons to Responses Elicited by M. bovis bacille Calmette Guerin

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Scherer, C.F., Estes, D.M., Jacobs, W.R., Glatman-Freedman, A., Larsen, M.H. 2007. Failure of a Mycobacterium tuberculosis DeltaRD1 DeltapanCD Double Deletion Mutant in a Neonatal Calf Aerosol M. bovis Challenge model: Comparisons to Responses Elicited by M. bovis bacille Calmette Guerin. Vaccine. 25(45):7832-7840.Efficacy of Oral and Parenteral Routes of Mycobacterium bovis bacille Calmette-Guerin Vaccination Against Experimental Bovine Tuberculosis in White-tailed deer (Odocoileus virginianus):   A Feasibility Study

- (Peer Reviewed Journal)Nol, P., Palmer, M.V., Waters, W.R., Aldwell, F.E., Buddle, B.M., Triantis, J., Linke, L., Phillips, G., Thacker, T.C., Rhyan, J., Dunbar, M., Salman, M.D. 2008. Efficacy of Oral and Parenteral Routes of Mycobacterium bovis bacille Calmette-Guerin Vaccination Against Experimental Bovine Tuberculosis in White-tailed deer (Odocoileus virginianus):  A Feasibility Study. Journal of Wildlife Diseases. 44(2):247-259.Bovine Tuberculosis:  Analyzing the Parameters of the Interferon Gamma Assay and Improved Diagnosis with New Antigens

- (Abstract Only)Schiller, I., Vordermeier, M., Waters, W.R., Marg-Haufe, B., Palmer, M.V., Thacker, T.C., Hardegger, R., Kyburz, A., Raeber, A., Oesch, B. 2007. Bovine Tuberculosis:  Analyzing the Parameters of the Interferon Gamma Assay and Improved Diagnosis with New Antigens [abstract].Lesion Development and Immunohistochemical Changes in Granulomas from Cattle Experimentally Infected with Mycobacterium bovis

- (Peer Reviewed Journal)Palmer, M.V., Waters, W.R., Thacker, T.C. 2007. Lesion Development and Immunohistochemical Changes in Granulomas from Cattle Experimentally Infected with Mycobacterium bovis. Veterinary Pathology. 44(6):863-874.Vaccination of White-tailed Deer (Odocoileus virginianus) with Mycobacterium bovis bacillus Calmette Guerin

- (Peer Reviewed Journal)Palmer, M.V., Thacker, T.C., Waters, W.R. 2007. Vaccination of White-tailed Deer (Odocoileus virginianus) with Mycobacterium bovis bacillus Calmette Guerin. Vaccine. 25(36):5489-97.Associations between Cytokine Gene Expression and Pathology in Cattle infected with Mycobacterium bovis

- (Abstract Only)Thacker, T.C., Palmer, M.V., Waters, W.R. 2007. Associations between Cytokine Gene Expression and Pathology in Cattle infected with Mycobacterium bovis. [Abstract].  American Association for Microbiology. Abstract No. U-037.The Neonatal calf Tuberculosis Vaccine Model:  Immune Responses to Protective and Non-protective Vaccines after Aerosol Challenge with Virulent Mycobacterium bovis

- (Abstract Only)Waters, W.R., Palmer, M.V., Nonnecke, B.J., Thacker, T.C., Estes, M., Jacobs, W.R., Larsen, M.L. 2007. The Neonatal calf Tuberculosis Vaccine Model:  Immune Responses to Protective and Non-protective Vaccines after Aerosol Challenge with Virulent Mycobacterium bovis [abstract]. The American Association of Immunologists. p. 43.51.Associations Between Cytokine Gene Expression and Pathology in Mycobacterium bovis Infected Cattle

- (Peer Reviewed Journal)Thacker, T.C., Palmer, M.V., Waters, W.R. 2007. Associations Between Cytokine Gene Expression and Pathology in Mycobacterium bovis Infected Cattle. Veterinary Immunology and Immunopathology. 119(3-4):204-213.Blood Culture and Stimulation Conditions for the Diagnosis of Tuberculosis in Cervids by the Cervigam Assay

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Thacker, T.C., Orloski, K., Nol, P., Harrington, N.P., Olsen, S.C., Nonnecke, B.J. 2008. Blood Culture and Stimulation Conditions for the Diagnosis of Tuberculosis in Cervids by the Cervigam Assay. Veterinary Record. 162(7):203-208.INTERPRETATION OF TUBERCULOSIS DIAGNOSTIC TEST RESULTS MAY BE CONFOUNDED IN CATTLE INFECTED WITH MYCOBACTERIUM KANSASII

- (Abstract Only)Waters, W.R., Palmer, M.V., Thacker, T.C., Harris, N.B., Payeur, J.B., Minion, F.C., Mcnair, J., Pollock, J.M., Lyashchenko, K.P. 2006. Interpretation of tuberculosis diagnostic test results may be confounded in cattle infected with Mycobacterium kansasii [abstract]. Research Workers in Animal Diseases Conference Proceedings. p. 81.VACCINATION OF WHITE-TAILED DEER WITH MYCOBACTERIUM BOVIS BACILLUS CALMETTE GUERIN (BCG)

- (Abstract Only)Palmer, M.V., Thacker, T.C., Waters, W.R. 2006. Vaccination of white-tailed deer with mycobacterium bovis bacillus calmette guerin (bcg)[abstract]. American Association of Veterinary Laboratory Diagnosticians. p. 122.VACINATION OF WHITE-TAILED DEER WITH MYCOBACTERIUM BOVIS BACILLUS CALMETTE GUERIN (BCG)

- (Abstract Only)Palmer, M.V., Thacker, T.C., Waters, W.R. 2006. Vaccination of white-tailed deer with Mycobacterium bovis bacillus Calmette Guerin (BCG). [abstract]. In:  Michigan Bovine Tuberculosis 11th Annual Meeting, June 7-8, 2006, Lansing, Michigan, 2006 CDROM.ORAL BACILLE CALMETTE-GUERIN (BCG) VACCINATION OF WHITE-TAILED DEER AGAINST BOVINE TUBERCULOSIS

- (Abstract Only)Nol, P., Palmer, M.V., Waters, W.R., Thacker, T.C., Rhyan, J., Aldwell, F., Buddle, B., Dunbar, M., Salman, M. 2006. Oral bacille Calmette-Guerin (BCG) Vaccination of White-tailed Deer against Bovine Tuberculosis [abstract]. In:  Michigan Bovine Tuberculosis 11th Annual Meeting, June 7-8, 2006, Lansing, Michigan, 2006 CDROM.CORRELATION OF CYTOKINE GENE EXPRESSION WITH PATHOLOGY IN WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) INFECTED WITH MYCOBACTERIUM BOVIS

- (Peer Reviewed Journal)Thacker, T.C., Palmer, M.V., Waters, W.R. 2006. Correlation of Cytokine Gene Expression with Pathology in White-Tailed Deer (Odocoileus virginianus) Infected with Mycobacterium bovis. Clinical and Vaccine Immunology.  13(6):640-647.EARLY ANTIBODY RESPONSES TO EXPERIMENTAL MYCOBACTERIUM BOVIS INFECTION OF CATTLE

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Thacker, T.C., Bannantine, J.P., Vordermeier, H.M., Hewinson, R.G., Greenwald, R., Esfandiari, J., Mcnair, J., Pollock, J.M. 2006. Early Antibody Responses to Experimental Mycobacterium bovis Infection of Cattle. Clinical and Vaccine Immunology.  13(6):648-654.IMMUNE RESPONSES TO DEFINED ANTIGENS OF MYCOBACTERIUM BOVIS IN CATTLE EXPERIEMNTALLY INFECTED WITH MYCOBACTERIUM KANSASII

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Thacker, T.C., Payeur, J.B., Harris, N.B., Minion, F.C., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J. 2006. Immune Responses to Defined Antigens of Mycobacterium bovis in Cattle Experimentally Infected with Mycobacterium kansasii. Clinical and Vaccine Immunology. 13(6):611-619.ANTIGEN SPECIFIC PROLIFERATION AND ACTIVATION OF PERIPHERAL BLOOD MONONUCLEAR CELLS FROM MYCOBACTERIUM BOVIS-INFECTED REINDEER

- (Peer Reviewed Journal)Waters, W.R., Palmer, M.V., Thacker, T.C., Minion, F.C., Davis, W.C. 2006. Antigen-specific proliferation and activation of peripheral blood mononuclear cells from Mycobacterium bovis-infected reindeer. Veterinary Immunology and Immunopathology.  111(2006): 263-277.EFFECT OF DIFFERENT TUBERCULIN SKIN-TESTING REGIMENS ON GAMMA INTERFERON AND ANTIBODY RESPONSES IN CATTLE EXPERIMENTALLY INFECTED WITH MYCOBACTERIUM BOVIS

- (Peer Reviewed Journal)Palmer, M.V., Waters, W.R., Thacker, T.C., Lyashchenko, K. 2006. Effect of Different Tuberculin Skin-Testing Regimens on Gamma Interferon and Antibody Responses in Cattle Experimentally Infected with Mycobacterium bovis. Clinical and Vaccine Immunology.  13(3):387-394.EFFECTS OF DIFFERENT SKIN TESTING REGIMENS ON INTERFERON GAMMA AND ANTIBODY RESPONSES IN CATTLE EXPERIMENTALLY INFECTED WITH MYCOBACTERIUM BOVIS

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Minion, F.C., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J., Pollock, J., Lyashchenko, K. 2005. Effects of Different Skin Testing Regimens on Interferon gamma and Antibody Responses in Cattle Experimentally Infected with Mycobacterium Bovis [abstract]. International Conference on Mycobacterium bovis. p. 24.EXPERIMENTAL INFECTION OF REINDEER (RANGIFER TARANDUS) WITH MYCOBACTERIUM BOVIS:  PATHOLOGICAL AND IMMUNOLOGICAL FINDINGS

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Stoffregen, W.C., Slaughter, R.E., Jones, S.L., Pitzer, J.E., Minion, F.C. 2005. Experimental Infection of Reindeer (rangifer tarandus) with Mycobacterium bovis:  Pathological and Immunological Findings[abstract]. International Conference on Mycobacterium bovis. p. 70.LESION DEVELOPMENT AND IMMUNOHISTOCHEMICAL CHANGES IN CATTLE EXPERIMENTALLY INFECTED WITH MYCOBACTERIUM BOVIS

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Whipple, D.L. 2005. Lesion Development and Immunohistochemical Changes in Cattle Experimentally Infected with Mycobacterium bovis [abstract]. International Conference on Mycobacterium bovis. p. 70.WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) CYTOKINE EXPRESSION IN RESPONSE TO INFECTION WITH MYCOBACTERIUM BOVIS

- (Abstract Only)Thacker, T.C., Palmer, M.V., Waters, W.R. 2005. White-tailed deer (odocoileus virginianus) Cytokine Expression in Response to Infection with Mycobacterium Bovis [abstract]. International Conference on Mycobacterium bovis.  Paper No. 3085.MYCOBACTERIUM KANSASII INFECTION OF CATTLE CONFOUNDS INTERPRETATION OF TUBERCULOSIS DIAGNOSTIC TESTS

- (Abstract Only)Waters, W.R., Palmer, M.V., Thacker, T.C., Payeur, J.B., Minion, F.C., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J., Pollock, J.M. 2005. Mycobacterium Kansasii Infection of Cattle Confounds Interpretation of Tuberculosis Diagnostic Tests [abstract]. International Conference on Mycobacterium bovis. p. 26.EXPERIMENTALLY INDUCED INFECTION OF REINDEER (RANGIFER TARANDUS) WITH MYCOBACTERIUM BOVIS

- (Peer Reviewed Journal)Palmer, M.V., Waters, W.R., Thacker, T.C., Stoffregen, W.C., Thomson, B.V. 2006. Experimentally induced infection of reindeer (Rangifer tarandus) with Mycobacterium bovis. Journal of Veterinary Diagnostic Investigation.  18(2006):52-60.EFFECTS OF DIFFERENT SKIN TESTING REGIMENS ON INTERFERON GAMMA AND ANTIBODY RESPONSES IN CATTLE EXPERIMENTALLY INFECTED WITH MYCOBACTERIUM BOVIS

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Minion, C.F., Greenwald, R., Esfandiari, J., Andersen, P., Mcnair, J., Pollock, J., Lyashchenko, K. 2005. Effects of different skin testing regimens on interferon gamma and antibody responses in cattle experimentally infected with Mycobacterium bovis [abstract]. American Association of Veterinary Laboratory Diagnosticians. p. 7.ANTIGEN-SPECIFIC PROLIFERATION AND ACTIVATION OF PERIPHERAL BLOOD MONONUCLEAR CELLS FROM MYCOBACTERIUM BOVIS-INFECTED REINDEER

- (Proceedings)Waters, W.R., Palmer, M.V., Thacker, T.C., Minion, F.C., Davis, W.C. 2004. Antigen-specific proliferation and activation of peripheral blood mononuclear cells from mycobacterium bovis-infected reindeer. Research Workers in Animal Diseases Conference Proceedings.  85:98.EXPERIMENTAL INFECTION OF REINDEER (RANGIFER TARNDUS) WITH MYCOBACTERIUM BOVIS; PATHOLOGICAL AND IMMUNOLOGICAL FINDINGS AT: AMERICAN ASSOCIATION OF VETERINARY LABORATORY DIAGNOSTICIANS ANNUAL MEETING. GREENSBORO, NC.

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Stoffregen, W.C., Slaughter, W.E., Jones, S.L., Pitzer, J.E., Minion, F.C. 2004. Experimental infection of reindeer (rangifer tarndus) with mycobacterium bovis; pathological and immunological findings [abstract]. American Association of Veterinary Laboratory Diagnosticians. p. 97.EXPERIMENTAL INFECTION OF REINDEER (RANGIFER TARANDUS)WITH MYCOBACTERIUM BOVIS; PATHOLOGICAL AND IMMUNOLOGICAL FINDINGS

- (Abstract Only)Palmer, M.V., Waters, W.R., Thacker, T.C., Stoffregen, W.C., Slaughter, R.E., Jones, S.L., Pitzer, J.E., Minion, F.C. 2004. Experimental infection of reindeer (rangifer tarandus)with mycobacterium bovis; pathological and immunological findings [abstract]. Wildlife Disease Association. p.402-403.WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) CYTOKINE EXPRESSION IN RESPONSE TO INFECTION WITH MYCOBACTERIUM BOVIS

- (Proceedings)Thacker, T.C., Palmer, M.V., Waters, W.R. 2004. White-tailed deer (odocoileus virginianus) cytokine expression in response to infection with mycobacterium bovis. Proceedings of Keystone Symposia. p.119.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov