Partikian 1

Juliana, et al. v. United States, et al.

Case No. 15-cv-1517 (D. Or.)

EXPERT REPORT OF DR. ARTHUR PARTIKIAN

I am a medical doctor and have been so licensed in the State of California since 2003, specializing in 

Pediatric Neurology and Epilepsy. I am board certified in Neurology from the American Board of 

Psychiatry and Neurology with special qualifications in Child Neurology since 2008 and in Epilepsy 

since 2017. I received my Doctorate of Medicine from Washington University School of Medicine, St. 

Louis Missouri in 2002, followed by combined residency training from 2002-2007 in General 

Pediatrics and Child Neurology at Children’s Hospital Los Angeles, which is affiliated with University 

of Southern California. At present, I am a Clinical Associate Professor of Pediatrics & Neurology at the 

Keck School of Medicine of University of Southern California, Los Angeles, California. I am also the 

Director of the Division of Child Neurology at Los Angeles County + U.S.C. Medical Center in Los 

Angeles, California, and a Senior Physician in the L.A. County Department of Health Services. I have 

been dually employed by Los Angeles County and by the University of Southern California since 2007. 

A true and correct copy of my curriculum vitae, which contains an accurate summary of my education, 

training and experience, is attached as Exhibit 1. In addition, I have attached a listing of my recent 

deposition and trial testimony as an expert as Exhibit 2. 

In that capacity, I have been retained by the Defendants in the above-referenced case. Specifically, I 

will be discussing whether the Plaintiffs’ experts have appropriately characterized and/or applied 

standard of care medical practice in their expert opinions in this case relative to neurological impacts 

referenced in those experts’ reports. 

I understand that discovery in this case, including but not limited to depositions, remains ongoing. 

To the extent that additional information is revealed in discovery that warrants revisiting or 

supplementing my opinions and conclusions, I reserve the right to do so. 

I have reviewed and am relying on the following documents and reports in this case: 

1. First Amended Complaint for Declaratory and Injunctive Relief

2. Declarations of the twenty-one individual Plaintiffs in Support of Plaintiffs’ Opposition to 

Defendants’ Motion for Summary Judgment 

3. Expert Report of Dr. Susan Pacheco and Dr. Jerome Paulson

4. Expert Report of Dr. Howard Frumkin

5. Expert Report of Dr. Lise Van Susteren, including Exhibit C Assessments of Plaintiffs 

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 1 of 16
Partikian 2

The opinions expressed in this report are based upon my review of the above-listed records and 

documents, as well as my education, training and experience. My opinions in this case are held to a 

reasonable degree of medical probability and based on my clinical and educational experience in 

Pediatric Neurology. I am being compensated for my work in this case at the rate of $540 per hour. 

My compensation is not contingent on the outcome of this lawsuit. The views I express in this report 

reflect my professional opinions only and are independent of my employers. 

Drs. Pacheco and Paulson state in their expert report (p.28) that “Children exposed to certain climate 

change and air pollutants, can experience changes to neurological development, with life-long 

consequences.” They also site the Targeting Environmental Neurodevelopmental Risks (TENDR) 

Consensus Statement that air pollutants, including nitrogen dioxide and particulate matter, are 

“prime examples of toxic chemicals that can contribute to learning, behavioral or intellectual 

impairment, as well as specific neurodevelopmental disorders such as attention deficit hyperactivity 

disorder or autism.” They cite a study by Perrera et al. from 2014 that children exposed to higher 

levels of polycyclic aromatic hydrocarbons in earlier childhood “continued to manifest adverse 

neurocognitive impacts – including anxiety, depression and hyperactivity – as compared to children 

with lower PAH exposure.” All three Plaintiffs’ expert reports assert that the Plaintiffs have already 

suffered health effects due to climate change, and that these health effects will be worsened in the 

future unless the deleterious impacts of climate change are remedied. 

In order to assess the validity of the above-referenced opinions, I would expect, at the least, that 

standard of care medical techniques be applied to objectively characterize and to evaluate these 

various health effects and their potential causes so that accurate diagnostic conclusions may be 

reached. In my review of the twenty-one Plaintiffs’ Declarations, I focused on whether there was

evidence of any direct neurological harm. In some of these Declarations, I found mention of 

secondary headaches from perceived exacerbation of underlying allergies, asthma, infections and/or 

excessive heat (Zealand B., Jaime B., Jayden F. and Avery M.) and perhaps some exacerbation of 

primary migraine headaches (Jayden F.). However, I could not adequately assess the quality, 

duration, impact, and related causal factors which could have contributed to these headache 

manifestations due to a paucity of information and lack of any medical records. In particular, I found 

missing the usual documentation and details that physicians should rely upon in order to 

characterize an individual’s headache complaints and to formulate an appropriate differential 

diagnosis, assessment, and plan of therapeutic action. At the least, an adequate medical history 

regarding the headache pain quality, duration, frequency, mitigating and exacerbating factors, other 

possible triggers, family history, and examination findings should be solicited and documented by a 

clinician or expert. Such information is fundamental and necessary in adequately characterizing and 

assessing an individual’s complaints of headaches (Lewis et al. 2002 and Pina-Garza 2013). While I 

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 2 of 16
Partikian 3

do not contest the general concept that factors mentioned by the Plaintiffs’ experts as potentially 

associated with climate change—such as excessive heat, dehydration, psychological stress, and acute 

or chronic infections causing inflammation—can trigger secondary headaches or exacerbate a 

primary headache condition, I do not find adequate documentation in the available records and 

reports in this lawsuit to reach the conclusion as a practicing physician that climate change is the 

main trigger for the Plaintiffs’ headaches. 

Similarly, in order to determine that a person is suffering from other neurological insults—such as

substantial cognitive or learning deficits, cortical visual or auditory dysfunction, upper or lower 

motor neuron disorders including muscle or nerve disease, developmental delays or disabilities, and 

inflammatory or autoimmune diseases of the central or peripheral nervous system—I would expect 

that an appropriate history be obtained, an adequate physical examination performed, and, if 

indicated, additional diagnostic testing be conducted. These basic but fundamental steps of clinical 

investigation, which are necessary in order to reach medical diagnoses, have not been completed by 

the Plaintiffs’ experts as far I can tell. Consequently, I find no objective evidence or appropriate 

diagnostic testing demonstrating that Plaintiffs are suffering from any neurological disorders 

identified earlier in this paragraph. While a substantial body of literature referred to by the 

Plaintiffs’ experts (in addition to others that I reviewed1) have demonstrated an increased 

association or risk of various health effects, including neurological and psychological impacts, with 

climate change, these studies do not independently establish that the Plaintiffs’ specific health effects 

are primarily caused by climate change and its possible repercussions. For routine medical 

purposes, such diagnostic conclusions in general should be verified by standard-of-care procedures 

and processes applied by an appropriately trained and experienced clinician. 

Finally, the majority of the Plaintiffs and all three Plaintiffs’ Expert reports emphasize mental health 

and allergy concerns. As a Pediatric Neurologist, I would defer to a mental health expert to 

adequately assess an individual’s psychological complaints. From my vantage point as a Pediatric 

Neurologist, the assessment of such complaints should include investigation for past or ongoing 

experiences of adverse events—which might or might not be related to climate change, 

familial/genetic predisposition to mental health disorders, any toxin or concurrent medication 

exposures which could have psychological impacts, and any co-morbid cognitive, social and/or 

physical conditions which could affect behavioral and psychological problems. Similarly, I would 

defer the comprehensive medical evaluation of complaints of purported allergy or asthma symptoms 

and signs to an Allergist-Immunologist. 

 

1 These studies, in addition to those formally referenced in my Report, are attached as Exhibit 3. 

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 3 of 16
Partikian 4

Arthur Partikian, M.D.

Board Certified in Epilepsy & Neurology with special qualification in Child Neurology

Report Completed on 8/13/2018

References: 

Lewis, D.W. et al. “Practice parameter: evaluation of children and adolescents with recurrent 

headaches. Report of the Quality Standards Subcommittee of the American Academy of Neurology 

and the Practice Committee of the Child Neurology Society.” NEUROLOGY 2002;59, pages 490–498 

Pina-Garza, J. Eric. “Chapter 3: Headache” in Fenichel’s Clinical Pediatric Neurology, 7th Edition: A 

signs and symptoms approach. 2013, pages 76-88. Retrieved from: https://www-sciencedirectcom.libproxy2.usc.edu/book/9781455723768/fenichels-clinical-pediatric-neurology#book-info

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 4 of 16
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CURRICULUM VITAE

ARTHUR PARTIKIAN

PERSONAL INFORMATION:

EDUCATION/APPOINTMENTS:

EDUCATION:

Year Degree, Field, Institution, City

1994 G.E.D., Glendale High School, Glendale, CA

1998 B.A., Pomona College, Claremont, CA

2002 M.D., Washington University School of Medicine, St. Louis, MO

POST-GRADUATE TRAINING:

Year-Year Training Type, Field, Mentor, Department, Institution, City

2002-2003 Internship, General Pediatrics, Children’s Hospital Los Angeles, Los Angeles, CA

2003-2004 Residency, General Pediatrics, Children’s Hospital Los Angeles, Los Angeles, CA

2004-2007 Residency, Child Neurology, Children’s Hospital Los Angeles, Los Angeles, CA

ACADEMIC APPOINTMENTS:

Year-Year Appointment Department, Institution, City, Country

2008-2018 Assistant Professor of Clinical 

Pediatrics & Neurology

Departments of Pediatrics & Neurology, Keck School of 

Medicine, U.S.C., Los Angeles

2018-present Clinical Associate Professor of 

Pediatrics & Neurology (Clinician 

Educator Track)

Departments of Pediatrics & Neurology, Keck School of 

Medicine, U.S.C., Los Angeles

ADMINISTRATIVE & CLINICAL APPOINTMENTS:

Year Description Institution, City, State, Country

2007-present Director of Division of Child 

Neurology

LAC+USC Medical Center, Los Angeles, CA

2012-present Medical Director of Epilepsy 

Dietary Program

LAC+USC Medical Center, Los Angeles, CA

2013-present Senior Physician Department of Health Services of LA County, LAC+USC Medical 

Center, Los Angeles, CA

LICENSURE, CERTIFICATIONS

LICENSURE

2003 A85112, California, expires 11/30/2019

BOARD CERTIFICATION OR ELIGIBILITY 

2008 American Academy of Psychiatry & Neurology, Neurology with special qualification in Child Neurology, 

valid through 12/31/2018

SPECIALTY CERTIFICATION 

2017 American Academy of Psychiatry & Neurology, California, Epilepsy, passed

Work

2010 Zonal Ave

Building B, 3P61

LAC+USC Medical Center

Los Angeles, CA 90031

Phone: 323-409-3442

Work Email: apartiki@usc.edu;apartikian@dhs.lacounty.gov 

Personal Email: partikian@gmail.com

Citizenship: USA

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HONORS, AWARDS:

Year Description Awarding agency, address, city

1998-2002 Distinguished Alumni 

Scholarship 

(full-tuition, merit based) 

Washington University School of Medicine, St. Louis MO

2002 Medical Student Prize for 

Excellence in Neurology

American Academy of Neurology

2004 General Pediatrics Resident 

Award for outstanding

Outpatient care

Children’s Hospital Los Angeles, Los Angeles, CA

2004 Affiliates Award for excellence 

In clinical care as a General 

Pediatrics Resident

Children’s Hospital Los Angeles, Los Angeles, CA

2005 Annual Fellow Teaching Award Children’s Hospital Los Angeles, Los Angeles, CA

2008 & 2011 Annual Faculty Teaching Award Pediatrics Department, Keck School of Medicine at U.S.C.

2012 Recognition Award for 

Establishing Dietary Epilepsy

Program at LAC+USC Center

The Charlie Foundation to Help Cure Pediatric Epilepsy

2014 Passionate Performance Award 

For establishing a “regionally 

Recognized Pediatric Epilepsy 

Program” at LAC+USC Center

Los Angeles County Department of Health Services

2014 Honorary Faculty Member USC Gamma Chapter of Alpha Omega Alpha (AOA) Honor

Medical Society, Keck School of Medicine of U.S.C.

2016 Annual Faculty Teacher of the

Year Award 

Neurology Department, Keck School of Medicine at U.S.C.

TEACHING

DIDACTIC TEACHING:

LAC+USC Medical Center

Year-Year Course Name Units/Hrs Role

2007-present Pediatric Neurology Elective N/A Clinical Preceptor, Elective Organizer & Lecturer:

update & oversee clinical curriculum and

supervision of KSOM medical students, General 

Pediatrics, combined Med-Peds, and Neurology 

rotating Housestaff

2013-present Epileptology Faculty N/A Clinical Preceptor & Lecturer for adult neurology 

 epileptology fellow rotating through LAC+USC

Children’s Hospital Los Angeles

Year-Year Course Name Units/Hrs Role

2009-present Rett Syndrome Clinic Rotation N/A Clincal Preceptor & Lecturer

CME COURSES DEVELOPED

Institution

Year-Year Course Name Units/Hrs Role

USC, 2010

CHLA, 2016

Van Der Meulen Epilepsy 

Conference 

Epilepsy Update Conference

8

8

Faculty participant, Speaker

Faculty participant, Speaker

USC, 2018 Van Der Meulen Epilepsy 

Conference 

8 Faculty participant, Speaker

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SERVICE 

DEPARTMENT SERVICE: 

HOSPITAL OR MEDICAL GROUP SERVICE:

Year-Year Position, Committee Organization/Institution

2007-present Member of Fetus, Infant & Child Ethics 

Committee

LAC+USC Medical Center

2007-present Faculty Member, Comprehensive Epilepsy 

Program

U.S.C., LAC+USC, & Rancho Los Amigo 

Medical Center

2015-present Panelist, Qualification & Appraisal Panel LAC+USC Medical Center

CONSULTANTSHIPS AND ADVISORY BOARDS:

Year Position, Board Organization/Hospital/School, Institution

2008-present Member, Professional Advisory Board Epilepsy Foundation of Greater Los Angeles

2010-present Neurology Consultant Rett syndrome clinic, CHLA

2014-present Neurology Consultant San Gabriel-Pomona Regional Center

2011 Invited Participant, Questcor Virtual Advisory BoardQuestcor Pharmaceuticals

2013 Invited Participant, Trokendi Regional 

Advisory Board

Supernus Pharmaceuticals

2014 Invited Participant, Onfi Advisory Board Lundbeck Pharmaceuticals

PROFESSIONAL SOCIETY MEMBERSHIPS:

Year- Year Society

2004-present American Academy of Neurology

2004-present Child Neurology Society of North America

2009-present American Epilepsy Society

2014-present Alpha Omega Alpha Medical Honor Society

ADMINISTRATIVE SERVICE/MAJOR LEADERSHIP POSITION:

Year Position Narrative listing Accomplishments- or add appendix

2007-present Director Director of Division of Child Neurology at LAC+USC. Established and continue to 

oversee clinical, academic, and educational goals and services of of this Division. 

Established pediatric EEG monitoring, dietary therapy, and neurostimulation access 

programs at LAC. Collaboration with USC Comprehensive Epilepsy Center & CHLA 

Leading efforts to recruit more pediatric neurology faculty at LAC. 

Year-Year Position, Committee Organization/Institution

2015 Member, Search Committee for Chair of Child 

Neurology at CHLA

Department of Pediatrics, Children’s Hospital 

Los Angeles

2015-present Faculty Member, Epilepsy Fellowship Program 

Evaluation Committee

KSOM at USC

2015-present

2017

Faculty Member, Clinical Competency 

Committee for Epilepsy Fellowship

Member, Ad Hoc Committee of Department of 

Neurology

KSOM at USC

LAC+USC Medical Center

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COMMUNITY SERVICE:

Year-Year Position Organization/Institution, City, Role or Activity

2008-present Member Epilepsy Foundation of Greater Los 

Angeles

Member of Professional Advisory Board, 

Invited Speaker at multiple annual “Care 

& Cure” fundraising events for pediatric 

epilepsy

2007 Participant Armenian Medical World Congress Travelled to Armenia and Karabagh with 

Dr. Berge Minassian and provided clinical 

care and educational support

2010 Medical Expert Epilepsy California Testified at California State Senate 

Health Committee regarding use of 

Diastat Acudial (rectal diazepam) as 

abortive therapy for students with 

epilepsy. Bill SB 1051

2011 Medical Expert Epilepsy California Testified at California State Senate 

Education Committee regarding use of 

Diastat Acudial as abortive therapy for 

students with epilepsy. 

2011 Medical Expert Epilepsy California Spoke at California Board of Education 

meeting regarding implementation of Bill 

SB 1051.

2012-present Medical Expert Rett Syndrome Clinic, CHLA Spoke as expert at various fundraising 

events sponsored by International Rett 

Syndrome Foundation & Rett Syndrome 

Research Trust

2015-present Co-creator & 

participant

“Carley’s Carbless Kitchen” monthly 

classes

Interactive cooking class open to the 

public and co-sponsored by Carley 

Eissman Foundation, Wellness Center

RESEARCH AND SCHOLARSHIP

MANUSCRIPT REVIEW:

Year-Year Journal

2010 The International Journal of Neuroscience

2010 Current Eye Research

2010 Neuropsychiatric Disease and Treatment

2011 Journal of Paediatrics and Child Health

2011-2014, 2017 Pediatrics

2013 Epilepsia

2015, 2017

2017

Journal of Child Neurology

Epileptic Disorders

MAJOR AREAS OF RESEARCH INTEREST

Research Areas

1. Pediatric Epilepsy, including treatment, comorbid conditions

2. Rett Syndrome

3. Ketogenic Diet applications

4. Modified Atkins Diet/MCT oil Diet for adults with intractable epilepsy

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GRANT SUPPORT - CURRENT:

Grant No. 003426-00003 (PI) (Toni Frederick, Ph.D.) Dates of Award: 8/2015 – present

Agency: Eunice Kennedy Shriver National Institute of Child Health 

and Human Development

Percent Effort: 2%

 Title: Surveillance Monitoring for ART Toxicities Study in HIV-uninfected Children Born to HIV-infected Women 

 (SMARTT study)

 Description: conduct & document neurological consultations for affected subjects

 Role: Neurology Consultant at LAC+USC Medical Center & Keck Medical Center of U.S.C.

Total Direct Costs: $499,553

Grant No. (PI) (Saman Hazany, M.D.) Dates of Award: 8/2015 – present

Agency: USC Department of Neuroimaging Percent Effort: 10%

Title: Ketogenic Diet Neuroimaging Study

Description: We are conducting a pilot study to investigate the potential neuroplasticity through detecting subtle change in 

structural, biochemical, and/or functional imaging indices associated with ketosis as a means of better understanding the 

impact of the ketogenic diet on seizure control. We plan to use a 3T GE scanner on the HSC campus, with 3D SPGR, DTI, 

resting state functional MRI and ASL MRI perfusion imaging. 

Role: Co-investigator at LAC+USC Medical Center and KSOM

Total Direct Costs: only cost of 10 scans is currently covered at HCC imaging center

Grant No. None (PI) (Arthur Partikian, M.D.) Dates of Award: 9/2018-8/2019

Agency: Vitaflo (International) Ltd. Percent Effort: 25%

Title: A pilot study on the feasibility and tolerability of Betaquik®, a special medical food containing medium chain triglycerides 

(MCT) as an adjunct to the dietary management of epilepsy and quality of life in adults on the modified Atkins diet (MAD)

 Description: This is an investigator-initiated exploratory pilot study to evaluate the gastrointestinal tolerance, 

 palatability and participant adherence, over a 26 week period, of the MAD including Betaquik, for the dietary 

 management of participants with intractable epilepsy at LAC+USC Medical Center

 Role: Primary Investigator

Total Direct Costs: $91,000

Grant No. None (PI) (Said Beydoun, M.D.) Dates of Award: projected 4/2018-10/2019

Agency: Pfizer Percent Effort: 2%

Title: A protocol to monitor from birth to age 15 months the neurological development of infants with exposure in-utero in 

tanezumab clinical studies at all investigational sites

Description: This is a multicenter, prospective, cohort study with enhanced physical and neurodevelopmental surveillance to 

characterize the neurological outcomes related to the development of infants up to the age of 15 months, who were exposed 

to tanezumab (a humanized IgG2 monoclonal antibody to Nerve Growth Factor), placebo or comparator via maternal 

exposure at conception or in-utero in any tanezumab clinical study. The post-natal monitoring will include assessments at 

birth (0-2 months), approximately 8 months and approximately 15 months of age and up to a maximum of 36 months of age 

as needed.

 GRANT SUPPORT - PENDING:

Role: Primary Investigator

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Total Direct Costs: under discussion

Grant No. N/A (PI) (Arthur Partikian, M.D.) Dates of Award: projected 2019

Agency: undetermined Percent Effort: 25%

 Title: A pilot study on the feasibility, safety and tolerability of ketogenic diet therapy for severe

 traumatic brain injury in children. 

 Description: This is a pilot study to evaluate the feasibility of implementation, safety and tolerability of ketogenic

 diet therapy for severe traumatic brain injury in children admitted to the pediatric intensive care unit at LAC+USC 

 Medical Center.

 Role: Primary Investigator

Total Direct Costs: $200,000 (estimate)

GRANT SUPPORT - PAST:

Grant No. None (PI) Arthur Partikian Dates of Award: 6/2014-6/2015, renewed in 2016

Agency: The Carley Eissman Foundation Percent Effort: 10%

 Title: The Dietary Therapy Program for Children & Adults with Epilepsy

 Description: Programmatic gift which provides support for Ketogenic Dietician and extends reach of our dietary 

 program to families with both public and private forms of insurance at Keck Medical Center of USC and 

 LAC+USC Medical Center

 Role: P.I. and Medical Director of Dietary Program at LAC+USC Medical Center

Total Direct Costs: $29,100 annually, renewed once in January 2016

Grant No. EFGLA 005 (Arthur Partikian, M.D.) Dates of Award: 9/2012-2/2014

Agency: Epilepsy Foundation of Greater Los Angeles Percent Effort: 25%

Title: The Dietary Therapy Program for Children with Epilepsy

 Description: This grant enabled the establishment of an active Dietary Therapy Program offering the classic

 ketogenic ratio system, modified Atkins diet, MCT oil therapy, or Low Glycemic Index Diet for children seen at the

Pediatric Neurology clinic of LAC+USC Medical Center.

 Role: As Medical Director & P.I., I was responsible for discussing dietary therapies in appropriate candidates,

 conducting diagnostic and laboratory testing to identify and prioritize patients as candidates, hiring and working

 with dedicated part-time Ketogenic Dietician, and for ongoing medical management of dietary patients. 

Total Direct Costs: $122,000

Grant No. None (PI) (Regina Berkovic, M.D.) Dates of Award: 2011-2013

Agency: Questcor Pharmaceutical Percent Effort: 2%

 Title: Comparison of Monthly Pulse Acthar gel Therapy with Methylprednisolone for Long-term Treatment of 

 Multiple Sclerosis as Add-On Therapy to Beta-Interferon

 Description: assess safety and efficacy of add-on ACTHar gel injections vs. Solumedrol in patients with multiple

 sclerosis receiving Avonex, Betaseron, or Rebif disease-modifying agents. 

 Role: Member of Safety Advisory Committee

Total Direct Costs: $125,024

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INVITED LECTURES, SYMPOSIA, KEYNOTE ADDRESSES

Year Type Title, Location

2008 Invited Lecture to 

Neurology Department

“X-linked Adrenoleukodystrophy,” Kaiser Permanente, Panorama City

2008 Invitied Lecture to 

Student Interest Group 

in Neurology

“Pediaric Neurology as a field,” Keck School of Medicine of U.S.C. 

2008 Symposia at Epilepsy 

State Forum: Improving 

Access to Care for 

Children and Youth with 

Epilepsy in California

“Shortage of Pediatric Neurologists: Issues and Barriers.” Invited by USC University 

Center For Excellence in Developmental Disabilities to Sacramento, CA

2007 to

2011

Invited Speaker & 

Panelist

“Childhood epilepsy: behavioral & neuropsychiatric connections.” Annual Epilepsy 

Brain Storm Summit, Epilepsy Foundation of Greater Los Angeles. Los Angeles, CA.

2009 Invited Lecture “Childhood Epilepsy: Developmental & Neuropsychiatric Connections.” U.S.C. 

University Center for Excellence in Developmental Disabilities Grand Rounds, Los 

Angeles, CA.

2013 Invited Lecture “Seizures and Movement Disorders in Rett Syndrome,” Rett Syndrome Conference at 

Children’s Hospital Los Angeles,

2015 Invited Lecture for 2 

hour session

“Communication and learning in individuals with severe disabilities: From the 

perspective of an interprofessional Rett Syndrome (RS) consultation team.” Panel 

Speaker for California Speech-Language-Hearing Association 2015 Annual conference, 

Long Beach, CA

2015 Invited Lectures “Dietary Therapy for Epilepsy,” “The U.S.C. Dietary Program,” & “Neuropsychological & 

Developmental Impact of Childhood Epilepsy,” Epilepsy Summit Los Angeles, 

Ketogenic Dietary Conference sponsored by Charlie Foundation & Epilepsy Foundation 

of Greater Los Angeles, Manhattan Beach, CA. Served as co-author for White Paper 

regarding this conference’s proceedings

2015

& 2016

Keynote Address “Dietary Therapy Options for Epilepsy,” at Epilepsy Awareness Day Education Expo at 

Disneyland, Anaheim, CA

2016 Panelist “Epilepsy Workshop,” at Los Angeles Zoo, sponsored by Epilepsy Foundation of 

Greater Los Angeles, Burbank, CA

2017 End Epilepsy Summit “Advances for Pediatric Epilepsies” and “Epilepsy in Rett Syndrome,” sponsored by 

Epilepsy Foundation of Greater Los Angeles, Universal City, CA

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INVITED GRAND ROUNDS, CME LECTURES

Year Type Title, Location

2008 Child & Adolescent 

Psychiatry Department 

Grand Rounds

“Leukodystrophies presenting with psychiatric manifestations,” LAC+USC Medical 

Center

2008 Neurology Grand Rounds “X-linked Adrenoleukodystrophy,” Keck Medical Center of U.S.C.

2009 Pediatrics Grand Rounds “Update on Infantile Spasms,” LAC+USC Medical Center

2009 Neurology Grand Rounds “Update on Infantile Spasms,” Children’s Hospital Los Angeles

2009 CME Lecture “Treatment of Neonatal Seizures: out with the old and in with the new?” Academic Day 

Conference for Neonatologist of Southern California at Children’s Hospital of Orange 

County, CA

2010 CME Lecture “Epilepsy in Children and Adolescents.” Van Der Meulen Conference sponsored by 

USC Department of Neurology, Los Angeles, CA

2010 Pediatrics Grand Rounds “Childhood Epilepsy Syndromes and their Neurodevelopmental Impact,” Children’s 

Hostpial Los Angeles

2011 Pediatrics Grand Rounds “Childhood Epilepsy Syndromes and their Neurodevelopmental Impact,” LAC+USC 

Medical Center

2013 CNE Lecture & Symposia “Childhood Epilepsy and its Neuropsychiatric Impact”. Plenary presentation of Epilepsy 

Update: Students with Seizures at 63rd Annual State Conference of the California 

School Nurses Organization, San Diego, CA.

2014 Pediatric Grand Rounds “Impact on Behavioral Problems on Quality of Life in Children with Epilepsy,” LAC+USC 

Medical Center.

2015 CME Lecture “Dietary Therapy for Epilepsy,” Epilepsy Summit Los Angeles, Ketogenic Dietary 

Conference sponsored by Charlie Foundation & Epilepsy Foundation of Greater Los 

Angeles, Manhattan Beach, CA.

2015 4 CNE lectures “Administration of Diastat & Intranasal Formulations in the Pipeline” and “Childhood 

Epilepsy and its Neuropsychiatric Impact.” Plenary presentation at Annual State 

Conference of the California School Nurses Organization (CSNO) in Anaheim, CA & at 

Southern California Regional CSNO Annual Conference in Monrovia, CA

2015 Short Course “Communication and Learning in Individuals with Severe Disabiliites: from the 

perspective of an Interprofessional Rett Syndrome Consultation Team.” 2015 Annual 

meeting of California Speech Language and Hearing Association, Long Beach, CA

2016 CME lecture “Home & School Seizure Rescue Plans,” 2016 Epilepsy Update sponsored by CHLA 

Epilepsy Department, Anaheim, CA

2017 CME lecture, 2 hour 

session

“Communication & Learning in Individuals with Severe Disabilities: Perspectives from 

an Interprofessional Rett Syndrome Team,” at the 2017 American Speech-LanguageHearing Association national convention, Los Angeles, CA

2017 Grand Rounds “Neurodevelopmental and Psychological Impact of Childhood Epilepsy,” Grand Rounds, 

Neurology Department, Harbor UCLA Medical Center

2017 CE Webinar Lecture “Refractory Epilepsy Patients: Management Options when Drugs Fail,” Webinar 

sponsored by Nutricia Learning Center

2018 Grand Rounds “Neurodevelopmental & Behavioral Impact of Childhood Epilepsy on Quality of 

Life: Beyond Seizure Control,” Grand Rounds, Neurology Department, Keck School of 

Medicine of USC

PUBLICATIONS:

REFEREED JOURNAL ARTICLES:

Format: Authors, Title. Journal. Volume #(Suppl ##):Page-Page, Year. PMID#, PMCID#, 

Narrative describing personal contribution.

Garza-Lopez R.A**., Byun D., Orellana K., Partikian A., Siew D., Yu A., and Kozak J.J. ‘Order-Disorder’ Phenomena in a 

Diffusion-Reaction Model of Interacting Dipoles on a Surface. J Chem Physics. 103: 9413-9417, 1995. Conducted modeling 

of diffusion reactions using linear algebra computer programming under supervision of college mentor. 

Partikian A, Olveczky, B, Swaminathan R. Li Y, Verkman AS.** Rapid diffusion of green fluorescent protein in the 

mitochondrial matrix. Journal of Cell Biology. 140(4):821-9, 1998. PMID: 947203. Conducted all FRAP (fluorescence 

recovery after photobleaching) experiments at UCSF, assisted with manuscript preparation and poster presentation under 

supervision of UCSF P.I. during American Heart Association Undergraduate Research Project. 

Qiu J, Bimston DN, Partikian A, Shen B.** Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA 

substrate interactions and cleavage site determination. J Biol Chem. 5;277(27):24659-66, 2002. PMID: 11986308. 

Conducted computer modeling of mutagenesis experiments impacting three-dimensional protein structure of FLAP 

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 12 of 16
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endonuclease under mentorship of Dr. Shen at City of Hope Beckman Research Institute as summer research assistant. 

Edited manuscript for grammar and clarity. 

Sun X, Wu P, Zheng L, Thrower D, Partikian A, Qiu J, Shen B.** Suppression of Saccharomyces cerevisiae rad27 null 

mutant phenotypes by the 5' nuclease domain of Escherichia coli DNA polymerase I. Present Gen. 41(6):379-88, 2002. 

PMID: 12228807. Provided benchtop support to senior researchers under mentorship of Dr. Shen at City of Hope Beckman 

Research Institute as summer research assistant. Edited manuscript for grammar and clarity.

Partikian, A** and Mitchell, WG.** Iatrogenic Botulism in a Child with Spastic Quadriparesis. J Child Neurol. (10): 1235-

1237, 2007. PMID: 17940253 . Organized clinical data, composed and edited manuscript, served as co-first author

Partikian, A.** and Mitchell, WG.** Major adverse events associated with treatment of infantile spasms. J Child Neurol. 

22(12):1360-1366, 2007. PMID: 18174552. Collected and analyzed data, composed and edited manuscript, served as cofirst author

Partikian, A. and Mitchell, WG. Neurodevelopmental and Epilepsy Outcomes in a North American Cohort of Infantile 

Spasms Patients. J Child Neurol. Vol. 25, No. 4, 423-428 (2010). PMID: 19749181. Collected and analyzed data, 

composed and edited manuscript, served as co-first author

Tai WA, Sanossian N, Partikian A, Mogensen M, Jones J, Liebeskind DS: Multimodal Neuroimaging Extends the Time 

Window for Thrombolytic Treatment in Pediatric Stroke. Journal of Pediatric Neuroradiology, 1(2): 2012. DOI: 10.3233/PNR2012-017. Reviewed and edited manuscript. 

Mittal A, Mittal G. Partikian A, and Sanossian N. Benefits of hemicraniectomy seen many years after malignant stroke in a 

young patient. Frontiers of Neurology. 3:123, 2012. PMID: 23015800. Reviewed and edited manuscript.

Manuscripts in the process of submission: 

Sandoval-Karamian AG, Stewart SB, Hoang LK, Ter-Zakarian A, Aldinger KA, Lane CJ, Partikian A. Significant impact of 

past trauma on behavioral problems and quality of life in a Hispanic pediatric cohort with epilepsy. Designed study, collected 

and helped to analyzed data, overseeing manuscript composition and editing, served as senior and corresponding author. 

Stewart SB, Sandoval-Karamian AG, Hoang LK, Aldinger KA, Ter-Zakarian A, Fishell AK, Lessov-Schlaggar CN, Partikian A. 

Quality of life and behavioral problems in children with epilepsy and developmental disability. Designed study, collected and 

helped to analyzed data, overseeing manuscript composition and editing, served as senior and corresponding author. 

REFEREED REVIEWS, CHAPTERS, AND EDITORIALS:

Partikian, A and Rosser, T: “Case 42: Cerebral sinus venous thrombosis; Case 46: Idiopathic torsion dystonia; Case 50: 

Hemorrhagic brain metastasis” in Pediatric Neurology: A Case-Based Review. Philadelphia: Lippincott Williams and 

Wilkins, 2006. 

W.G. Mitchell, A. Partikian, and L.S. Neinstein. “Epilepsy” in Adolescent Health Care: a Practical Guide. Fifth Edition (L.S. 

Neinstein et al, editors). Lippincott Williams & Wilkins, 2008. pages 329-345

W.G. Mitchell, A. Partikian, and L.S. Neinstein. “Epilepsy” in Handbook of Adolescent Health Care. (L.S. Neinstein et al, 

editors). Lippincott Williams & Wilkins, 2215-229

P. Shatry and A. Partikian. “11 yeal old female with dysphagia, dysarthria, and muscle weakness.” Pediatric Morning 

Report: Beyond the Pearls. Elsevier Publishing Company. Proposed for 2018. 

C. Vassillian and A. Partikian. “20 month old female with a febrile seizure.” Pediatric Morning Report: Beyond the Pearls. 

Elsevier Publishing Company. Proposed for 2018.

REFEREED ON-LINE PUBLICATIONS:

Partikian, A. First Unprovoked Seizure in Childhood, Evaluation and Treatment of Recurrent or Atypical Febrile Seizures in 

Childhood, Evaluation and Treatment of Pediatric Epilepsy, Evaluation and Treatment of Headaches in Children, Evaluation 

and Treatment of Cerebral Palsy. Recommendation guidelines for Primary Care Physicians in the LA County Department of 

Health Services. The Specialty Care Initiative is sponsored by Kaiser Permanente Southern California Community Benefit. 

Online: https://pcpcapacitybuilding.wordpress.com

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Page 10 of 11

NON-REFEREED JOURNAL ARTICLES, REVIEWS, OR OTHER COMMUNICATIONS:

Gutierrez J.Y.**, Partikian A., Lowe, J., Smith K., & Trejo S. Communication and Learning in Individuals with Severe 

Disabilities: from the perspective of an Interprofessional Rett Syndrome Consultation Team. California Speech Language 

and Hearing Association Magazine. Fall Issue 2015. 16-19. Contributed neurological perspective of factors influencing 

speech and language functioning and therapy services of individuals with Rett Syndrome, co-author. 

Zupec-Kania, Beth**, Partikian A. et al. “White Paper: Proceedings of Ketogenic Diet Therapies Symposium.” Published 

online: https://www.charliefoundation.org/explore-ketogenic-diet/explore-3/white-papers. 2015

ABSTRACTS AND PRESENTATIONS:

Partikian, A and Mitchell, WG. Adverse events associated with treatment of infantile spasms. American Academy of 

Neurology Annual Meeting, Boston, MA, April 2007

Melguizo I., Lin L., Sanossian N., and Partikian A. Neuroimaging diagnosis of X-ALD in a rapidly-deteriorating 8-year-old 

boy. American Society of Neuroimaging, Tuscon AZ, January 2008 

Partikian, A. and Mitchell, WG. Neurodevelopmental and Epilepsy Outcomes in a North American Cohort of Infantile 

Spasms Patients. American Epilepsy Society, Boston, MA, December 2009

Millett, D., Smith, Heck C, Kalayjian, L., Ko, D., Partikian, A., Gonzalez, A., Liu, C., and Jimenez, N. Intractable Epilepsy in 

an urban Hispanic population: a review of the first 100+ cases referred to an epilepsy monitoring unit. American Epilepsy 

Society, Boston, MA, December 2009

Kim P., Millett D., Heck C., Kalayjian L., Ko D., Shaw S., Partikian A., et al. Clinical utility of PET-MRI hybrid fusion in 

presurgical evaluation of intractable epilepsy. ASNR 2010

Weinkle J., Ter-Zakarian A., Stewart S.B., Aldinger K., Lane C.J., Partikian A. High Burden of Epilepsy and Disabilities in 

an Urban Hispanic Pediatric Cohort. 2012 Annual Child Neurology Society Meeting, Poster Session Abstracts. Annals of 

Neurology., Volume 72, Supplement S16, 2012. 

Partikian A., Sandoval A., Hoang L., Stewart S.B., Aldinger K. Significant impact of behavioral problems on quality of life in 

Hispanic urban children with epilepsy. Abstract 3.311 presented at 2012 Annual American Epilepsy Society Meeting, 

www.aesnet.org. December 2012 

Partikian A., Florendo E., Lane C.J., Stewart S., Sandoval A. Significant impact of past trauma on behavioral problems and 

quality of life in a Hispanic pediatric cohort with epilepsy. Abstract 2.218 presented at 2013 Annual American Epilepsy 

Society Meeting, www.aesnet.org. December 2013

Stewart S., Sandoval A., Lessov-Schlaggar C., Partikian A. The Negative Interaction of Behavioral Problems on Qualify of 

Life in a Pediatric Hispanic Epilepsy Cohort with Intellectual Disability. Preventitive Medicine annual conference, February 

2016. 

Lowe JM, Rosas H, Kalayjian L, Partikian A. Development of a teaching kitchen for the Modified Atkins Diet. 5th Global 

Symposium on Ketogenic Therapies: Treating Epilepsy, Brain Cancer, Autism & Cognitive Disorders. International 

Ketogenic Dietary Therapy Conference, September 2016

Lowe JM, Kalayjian L, Partikian A. Piloting an Interdisciplinary Seminar on the Ketogenic Diet for Physicians and Dieticiansin-training. 5th Global Symposium on Ketogenic Therapies: Treating Epilepsy, Brain Cancer, Autism & Cognitive Disorders. 

International Ketogenic Dietary Therapy Conference, September 2016

Ben-Nissan D, Lowe JM, Partikian A. The ketogenic diet in a patient with Leigh Syndrome: a case study. 5th Global 

Symposium on Ketogenic Therapies: Treating Epilepsy, Brain Cancer, Autism & Cognitive Disorders. International 

Ketogenic Dietary Therapy Conference, September 2016

Brown E, Lowe JM, Partikian A. Development of an Empowerment Questionnaire for families starting a ketogneic diet for 

epilepsy. 5th Global Symposium on Ketogenic Therapies: Treating Epilepsy, Brain Cancer, Autism & Cognitive Disorders. 

International Ketogenic Dietary Therapy Conference, September 2016

Hahn V, Lowe JM, Partikian A. MAD cooking class: a case study for self-efficacy improvement in an adolescent and their 

family. 5th Global Symposium on Ketogenic Therapies: Treating Epilepsy, Brain Cancer, Autism & Cognitive Disorders. 

International Ketogenic Dietary Therapy Conference, September 2016

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Stewart SB, Sandoval-Karamian AG, Milman LA, Lessov-Schlaggar CN, Partikian A. The association between intellectual 

disability and trauma exposure in Hispanic children with epilepsy. Preventive Medicine annual conference 2017

Yano S, Partikian A, Bluml S, Moseley K, Watanabe Y, Saitau H, Matsumoto N. Aspartate supplementation for AspartateGlutamate Carrier Isoform I deficiency. 2017 annual meeting of the American Society of Human Genetics. 

Brown J, Lowe JM, Partikian A. Feasibility of a ketogenic diet in low income communities in Los Angeles for intractable 

epilepsy. Oral Presenstation at 2017 Spring Summit on Ketogenic Diets for Neurological Disorders. 

Lowe JM, Trejo S, Gonzalez J, Smith K, Partikian A. The evaluation of malnutrition in children with Rett Syndrome: a 

single interdisciplinary center’s experience. Accepted for poster presentation at ASPEN 2018 Nutrition Science and Practice 

Conference

Lowe JM, Partikian A, et al. Pilot evaluation of a MAD cooking class for patients with epilepsy and their families. Accepted 

for poster presentation at 6th Global Symposium on Ketogenic Therapies for Neurological Disorders, Jeju, Korea, 10/2018

MEDIA AND TELEVISION APPEARANCES:

March 20, 2008. Dan Hurley. “Neurologists’ reaction varies widely to FDA safety alert on botulinum toxin for cerebral palsy.” 

Neurology Today. 

May 26, 2010. Steve Lopez. “Jumping down the rabbit hole in Sacramento.” Los Angeles Times. I was interviewed 

regarding expert testimony I provided for the California State Senate Health Committee about the safety and efficacy of 

Diastat Acudial. 

May 26, 2010. Jason Austell. “Could union jobs be trumping the health of children?” 

http://www.nbclosangeles.com/blogs/prop-zero. 

October 18, 2016. “Rett Syndrome, a rare and devastating neurological disorder,” ABC7 News segment interview, Los 

Angeles

Projected 2018. “Foster.” My clinical interactions with in-utero amphetamine exposed infant and other foster care youth are 

featured in this documentary by executive producer Deborah Oppenheimer. 

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 15 of 16
Deposition Testimony of Arthur Partikian, M.D. over the last four years: 

Shawn Gates vs. Home Depot (Case No: CV177200), Plaintiff Attorney that retained 

me: Richard Staskus. Deposition in September 2015. Cases involved head trauma 

and epilepsy. 

Jacob & Lisa Castellanos vs. Kaiser Foundation Health Plan (OIA #12809). Plaintiff 

Attorney that retained me: Paul Rosenfield of Gans & Rosenfield. Deposition on 

March 10, 2016. Case involves neonatal encephalopathy. 

Ashley Taylor vs. University of Utah (Case No: 140903769). Plaintiff Attorney that 

retained me: James W. McConkie. Deposition on 2/24/2017. Case involves 

baclofen pump failure. 

Tor vs. Hamzeh MD et al (Case No: 52-4850-01). Co-retained by Defense: 

Mark Franzen of Carroll, Kelly, Trotter, Franzen & McKenna and Curtis Holmes,II of 

BROBECK, WEST, BORGES, ROSA & DOUVILLE LLP. Deposition on 3/30/2017. Case 

involves neonatal brachial plexus injury and neonatal encephalopathy. 

Isabella Juliet Madrid vs. Adventist Medical Center-Reedley et al. (Case No. 13 CECG 

03829). Retained by Plaintiff Attorney Mr. Van Wagenen of Law Offices of Davis & 

Van Wagenen located in Fresno. Deposition on 4/27/2017 

All Trial Testimony: 

Tor vs. Hamzeh MD et al (Case No: 52-4850-01). Retained by Defense: 

Curtis Holmes, II of BROBECK, WEST, BORGES, ROSA & DOUVILLE LLP. Trial 

testimony on 5/8/2017 at the Superior Court of Orange County, Santa Ana, CA. Case 

involves neonatal brachial plexus injury and concern for neonatal encephalopathy. 

Case 6:15-cv-01517-AA Document 338-7 Filed 08/24/18 Page 16 of 16