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                    U.S. DEPARTMENT OF AGRICULTURE
 Foodborne Toxin Detection and Prevention Research: Albany, CA
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ARS Home Pacific West Area Albany, California Western Regional Research Center Foodborne Toxin Detection and Prevention Research People & Locations







Paula  Do
                        Foodborne Toxin Detection and Prevention Research

                        




                        
                        Biological Science Lab Technician
                        Phone: (510) 559-6478
                        
                        
                        Fax: (510) 559-6429(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            **Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)A sensitive cell-based assay for measuring low-level biological activity of a-amanitin
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2023. A sensitive cell-based assay for measuring low-level biological activity of a-amanitin. International Journal of Molecular Sciences. 24(22). Article e16402. https://doi.org/10.3390/ijms242216402.T-cell-receptor Vß8 for detection of biologically active streptococcal pyrogenic exotoxin type C
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2023. T-cell-receptor Vß8 for detection of biologically active streptococcal pyrogenic exotoxin type C. Journal of Dairy Science. 106(10):672-6730. https://doi.org/10.3168/jds.2023-23286.Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins
                                                        

- (Book / Chapter)Rasooly, R., Do, P.M., Hernlem, B.J. 2022. Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins. In: Ossandon, M.R., Baker, H., Rasooly, A., editors. Biomedical Engineering Technologies. Volume 1. New York, NY: Humana Press. p. 237-255. https://doi.org/10.1007/978-1-0716-1803-5_13.Human leukemia T-cell lines as alternative to animal use for detecting biologically active Staphylococcal enterotoxin type B
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2021. Human leukemia T-cell lines as alternative to animal use for detecting biologically active Staphylococcal enterotoxin type B. Toxins. 13(5). Article 300. https://doi.org/10.3390/toxins13050300.Quantitative bioluminescence assay for measuring Bacillus cereus nonhemolytic enterotoxin complex
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2020. Quantitative bioluminescence assay for measuring Bacillus cereus nonhemolytic enterotoxin complex. PLoS ONE. 15(9): Article e0238153. https://doi.org/10.1371/journal.pone.0238153.whISOBAXTM inhibits bacterial pathogenesis and enhances the effect of antibiotics
                                                        

- (Peer Reviewed Journal)Rasooly, R., Choi, H., Do, P.M., Morroni, G., Brescini, L., Cironi, O., Giacometti, A., Apostolidis, E. 2020. whISOBAXTM inhibits bacterial pathogenesis and enhances the effect of antibiotics. Antibiotics. 9(5):264. https://doi.org/10.3390/antibiotics9050264.CCD based detector for detection of Abrin toxin activity
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2020. CCD based detector for detection of Abrin toxin activity. Toxins. 12(2). https://doi.org/10.3390/toxins12020120.Witch hazel significantly improves the efficacy of commercially available teat dips
                                                        

- (Peer Reviewed Journal)Rasooly, R., Molnar, A., Do, P.M., Marroni, G., Brescini, L., Cirioni, O., Giavometti, A., Apostolidis, E. 2020. Witch hazel significantly improves the efficacy of commercially available teat dips. Pathogens. 9(2). Article 92. https://doi.org/10.3390/pathogens9020092.In-vitro inhibition of staphylococcal pathogenesis by witch-hazel and green tea extracts
                                                        

- (Peer Reviewed Journal)Rasooly, R., Molnar, A., Choi, H., Do, P.M., Racicot, K., Apostolidis, E. 2019. In-vitro inhibition of staphylococcal pathogenesis by witch-hazel and green tea extracts. Antibiotics. 8(4):244. https://doi.org/10.3390/antibiotics8040244.T cell receptor Vß9 in method to rapidly detect active staphylococcal enterotoxin type A without live animals
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2019. T cell receptor Vß9 in method to rapidly detect active staphylococcal enterotoxin type A without live animals. Toxins. 11:399. https://doi.org/10.3390/toxins11070399.Alternative to animal use for detecting biologically active Staphylococcal enterotoxin type A
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2018. Alternative to animal use for detecting biologically active Staphylococcal enterotoxin type A. Toxins. 10(12):540. https://doi.org/10.3390/toxins10120540.Sensitive low-cost CCD-based detector for determination of UV-LED water microbial disinfection
                                                        

- (Peer Reviewed Journal)Rasooly, R., Magoz, Z., Luo, J., Do, P.M., Hernlem, B.J. 2018. Sensitive low-cost CCD-based detector for determination of UV-LED water microbial disinfection. Desalination and Water Treatment. 118:120-125. https://doi.org/10.5004/dwt.2018.22667.Low cost bioluminescence imaging as an alternative to in vivo bioassays for quantifying biologically active staphylococcal enterotoxin type E
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2017. Low cost bioluminescence imaging as an alternative to in vivo bioassays for quantifying biologically active staphylococcal enterotoxin type E. Sensors and Actuators B: Chemical. 259:357-393. https://doi.org/10.1016/j.snb.2017.12.079.TCR-Vß8 as alternative to animal testing for quantifying active SEE
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2017. TCR-Vß8 as alternative to animal testing for quantifying active SEE. Journal of Environmental and Analytical Toxicology. 7(6):527. https://doi.org/10.4172/2161-0525.1000527.Interleukin 2 secretion by T cells for detection of biologically active Staphylococcal enterotoxin type E
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2017. Interleukin 2 secretion by T cells for detection of biologically active Staphylococcal enterotoxin type E. Journal of Food Protection. 80(11):1857-1862. https://doi.org/10.4315/0362-028X.JFP-17-196.Butterfly extracts show antibacterial activity
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Balaban, N., Wolferstan, P., Nash, R., Yael, G. 2017. Butterfly extracts show antibacterial activity. Journal of Agricultural and Food Chemistry. 7:467-479. doi:org/10.4236/aim.2017.76036.Rapid cell-based assay for detection and quantification of active staphylococcal enterotoxin type D
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2017. Rapid cell-based assay for detection and quantification of active staphylococcal enterotoxin type D. Journal of Food Science. doi: 10.1111/1750-3841.13634.Sensitive, rapid, quantitative and in vitro method for the detection of biologically active staphylococcal enterotoxin type E
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2016. Sensitive, rapid, quantitative and in vitro method for the detection of biologically active staphylococcal enterotoxin type E. Toxins. 8(5):150. doi: 10.3390/toxins8050150.Low cost quantitative digital imaging as an alternative to qualitative in vivo bioassays for analysis of active aflatoxin B1
                                                        

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2016. Low cost quantitative digital imaging as an alternative to qualitative in vivo bioassays for analysis of active aflatoxin B1. Journal of Agricultural and Food Chemistry. 80:405-410.The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA)

- (Peer Reviewed Journal)Friedman, M., Rasooly, R., Do, P.M., Henika, P.R. 2011. The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA). Journal of Food Science. 76:M558-M558. doi:10.1111/j.1750-3841.2001.02365.x.Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Hernlem, B.J. 2011. Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells. Open Journal of Immunology. 1(1):8-14. doi:10.4236/oji.2011.11002.Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization

- (Peer Reviewed Journal)Rasooly, R., Do, P.M. 2010. Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization. Journal of Agricultural and Food Chemistry. 58:12557-12561.Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Griffey, S.M., Vilches-Moure, J.G., Friedman, M. 2010. Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice. Journal of Agricultural and Food Chemistry. (58):9821-9286Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Friedman, M. 2010. Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols. Journal of Agricultural and Food Chemistry. 58:5421-5426.Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization

- (Peer Reviewed Journal)Rasooly, R., Do, P.M., Levin, C.E., Friedman, M. 2010. Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization. Applied and Environmental Microbiology. Vol. 75(5):M296-M301.Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization

- (Peer Reviewed Journal)Rasooly, R., Do, P.M. 2009. Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization. International Journal of Food Microbiology. 136(2010):290-294In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food

- (Peer Reviewed Journal)Rasooly, R., Do, P.M. 2009. In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food. FEMS Immunology and Medical Microbiology 56(2009): 172-178.In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food

- (Peer Reviewed Journal)Rasooly, R., Do, P.M. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. Applied and Environmental Microbiology. 74(14):4309-4313Detection of botulinum neurotoxin-A activity in food by peptide cleavage assay

- (Peer Reviewed Journal)Rasooly, R., Stanker, L.H., Carter, J.M., Do, P.M., Cheng, L.W., He, X., Brandon, D.L. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. International Journal of Food Microbiiology. 126 (2008):135-139
                    ARS News Articles
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                                                Foodborne Staph Toxin Pinpointed by New Assay


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