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                    U.S. DEPARTMENT OF AGRICULTURE
 Food Safety and Enteric Pathogens Research: Ames, IA
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ARS Home Midwest Area Ames, Iowa National Animal Disease Center Food Safety and Enteric Pathogens Research People & Locations







Kristen  Byrne
                        Food Safety and Enteric Pathogens Research

                        




                        
                        Research Biologist
                        Phone: (515) 337-6663
                        
                        
                        Fax: (Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsIntestinal Microbial Ecology and Non-Antibiotic Strategies to Limit Shiga Toxin-Producing Escherichia coli (STEC) and Antimicrobial Resistance Transmission in Food Animals
                                                    In-House Appropriated
                                                                    (D)Accession Number: 438679**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Altered cytokine production and gene expression by porcine monocytes following neonatal inoculation with bacillus Calmette-Guerin

- (Abstract Only)BCG induced innate training in neonatal and weaned pigs is dependent on route of administration

- (Abstract Only)Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils
                                                        

- (Peer Reviewed Journal)Herrera Uribe, J., Lim, K., Byrne, K.A., Daharsh, L., Liu, H., Corbett, R.J., Marco, G., Schroyen, M., Koltes, J.E., Loving, C.L., Tuggle, C.K. 2023. Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils. Frontiers in Genetics. 14. Article 1107462. https://doi.org/10.3389/fgene.2023.1107462.Short transportation did not impact circulating cortisol levels or leukocyte abundance in cattle

- (Abstract Only)Alternatives to Antibiotics: neonatal immunomodulation to improve disease resistance in animals

- (Abstract Only)Annotating cell transcriptomes in four immune tissues to establish a porcine single-cell Immune Atlas

- (Abstract Only)Improving blood phenomics: ISU station report

- (Abstract Only)Integrative profiling of gene expression and chromatin accessibility elucidates specific transcriptional networks in porcine neutrophils

- (Abstract Only)Characterization and applications of advanced regulatory element annotation in circulating porcine immune cells

- (Abstract Only)Definition of regulatory elements and transcription factors controlling immune cell gene expression at single cell resolution using single cell ATAC-Seq

- (Abstract Only)3’mRNA-Seq analysis of the effects of weaning and influenza infection on gene expression in whole blood of pigs

- (Abstract Only)Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity
                                                        

- (Peer Reviewed Journal)Kerr, B.J., Trachsel, J.M., Bearson, B.L., Loving, C.L., Bearson, S.M., Byrne, K.A., Pearce, S.C., Ramirez, S.M., Gabler, N.K., Schweer, W.P., Helm, E.T., De Mille, C.M. 2022. Evaluation of digestively resistant or soluble fibers, short- and medium-chain fatty acids, trace minerals, and antibiotics in nonchallenged nursery pigs on performance, digestibility, and intestinal integrity. Journal of Animal Science. 100(11). Article skac282. https://doi.org/10.1093/jas/skac282.Diversity of Alternative Splicing in Porcine Peripheral Blood Immune Cells

- (Abstract Only)Integration of epigenomic and transcriptomic data to identify regulatory elements and networks controlling immune cell-type gene expression in the pig

- (Abstract Only)Short chain fatty acids and bacterial taxa associated with reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in swine fed a diet supplemented with resistant potato starch
                                                        

- (Peer Reviewed Journal)Trachsel, J.M., Bearson, B.L., Kerr, B.J., Shippy, D.C., Byrne, K.A., Loving, C.L., Bearson, S.M. 2022. Short chain fatty acids and bacterial taxa associated with reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in swine fed a diet supplemented with resistant potato starch. Microbiology Spectrum. 10(3). Article e0220221. https://doi.org/10.1128/spectrum.02202-21.Intravenous BCG induction of innate memory in young pigs

- (Abstract Only)Integrative Profiling of Gene Expression and Chromatin Accessibility Elucidates Specific Transcriptional Networks in Porcine Neutrophils

- (Abstract Only)Converse trends with adaptive and innate immune responses following intravenous BCG inoculation in pigs

- (Abstract Only)Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing
                                                        

- (Peer Reviewed Journal)Herrera-Uribe, J., Wiarda, J., Sivasankaran, S.K., Daharsh, L., Liu, H., Byrne, K.A., Smith, T.P., Lunney, J.K., Loving, C.L., Tuggle, C.K. 2021. Reference transcriptomes of porcine peripheral immune cells created through bulk and single-cell RNA sequencing. Frontiers in Genetics. 12. Article 689406. https://doi.org/10.3389/fgene.2021.689406.Butyrate alters lipopolysaccharide-induced inflammatory response by porcine monocytes

- (Abstract Only)Integrative profiling of chromatin accessibility and gene expression elucidate specific transcriptional network in porcine neutrophils

- (Abstract Only)Characterization of circulating porcine immune cells using single-cell RNA-sequencing and comparison to human datasets

- (Abstract Only)Single cell and deep transcriptomic analysis identify common and cell type specific genes in porcine immune cell

- (Abstract Only)Differential induction of innate memory in porcine monocytes by B-glucan or bacillus Calmette-Guerin
                                                        

- (Peer Reviewed Journal)Byrne, K.A., Tuggle, C., Loving, C.L. 2020. Differential induction of innate memory in porcine monocytes by B-glucan or bacillus Calmette-Guerin. Innate Immunity. https://doi.org/10.1177/1753425920951607.Changes in H3K27ac at gene regulatory regions in porcine alveolar  macrophages following LPS or PolyIC exposure
                                                        

- (Peer Reviewed Journal)Uribe, J.H., Liu, H., Byrne, K.A., Bond, Z.F., Loving, C.L., Tuggle, C. 2020. Changes in H3K27ac at gene regulatory regions in porcine alveolar  macrophages following LPS or PolyIC exposure. Frontiers in Genetics. 11. https://doi.org/10.3389/fgene.2020.00817.Intraepithelial T cells diverge by intestinal location as pigs age
                                                        

- (Peer Reviewed Journal)Wiarda, J.E., Trachsel, J.M., Bond, Z.F., Byrne, K.A., Gabler, N.K., Loving, C.L. 2020. Intraepithelial T cells diverge by intestinal location as pigs age. Frontiers in Immunology. 11:1139. https://doi.org/10.3389/fimmu.2020.01139.Innate immunomodulation in food animals: evidence for trained immunity?
                                                        

- (Peer Reviewed Journal)Byrne, K.A., Loving, C.L., McGill, J.L. 2020. Innate immunomodulation in food animals: evidence for trained immunity? Frontiers in Immunology. 11:1099. https://doi.org/10.3389/fimmu.2020.01099.Novel engraftment and T cell differentiation of human hematopoietic cells in Art-/- IL2RG-/SCID pigs
                                                        

- (Peer Reviewed Journal)Boettcher, A.N., Li, Y., Ahrens, A.P., Kiupel, M., Byrne, K.A., Loving, C.L., Cino-Ozuna, A., Wiarda, J.E., Adur, M., Schultz, B., Swanson, J.J., Snella, E.M., Ho, C., Charley, S.E., Kiefer, Z.E., Cunnick, J.E., Putz, E.J., Giuseppe, Dell A., Jens, J., Sathe, S., Goldman, F., Westin, E.R., Dekkers, J.C.M., Ross, J.W., Tuggle, C.K. 2020. Novel engraftment and T cell differentiation of human hematopoietic cells in Art-I- IL2RG-IY SCID pigs. Frontiers in Immunology. 11:100. https://doi.org/10.3389/fimmu.2020.00100.


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