U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Manhattan, Kansas (NBAF)
 close




            Search small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home People & Locations







Ediane  Silva
                        Foreign Animal Disease Research

                        




                        
                        RESEARCH SCIENTIST
                        Phone:    
                        
                        
                        Fax: (Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsIntervention Strategies to Control and Eradicate Foreign Animal Diseases of Swine
                                                    In-House Appropriated
                                                                    (D)Accession Number: 441308Defining the Upper and Lower Respiratory Tract Transcriptome of Cattle Health and Disease
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 443407**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)ASF vaccine candidate ASFV-G-deltaI177l does not exhibit residual virulence in long-term clinical studies
                                                        

- (Peer Reviewed Journal)Borca, M.V., Ramirez Medina, E., Silva, E.B., Ayushi, R., Espinoza, N.N., Velazquez Salinas, L., Gladue, D.P. 2023. ASF vaccine candidate ASFV-G-deltaI177l does not exhibit residual virulence in long-term clinical studies. Pathogens. 12(6). https://doi.org/10.3390/pathogens12060805.Pathogenesis and transmissibility studies of the ASFV strain currently causing outbreaks in the Dominican Republic
                                                        

- (Abstract Only)Ramirez Medina, E., O'Donell, V., Silva, E.B., Espinoza, N.N., Velazquez Salinas, L., Moran, K., Daite, D., Barrette, R., Bonto, F., Holland, R., Gladue, D.P., Borca, M.V. 2023. Pathogenesis and transmissibility studies of the ASFV strain currently causing outbreaks in the Dominican Republic. Meeting Abstract. https://doi.org/10.3390/v14051090.Classical swine fever virus structural glycoprotein E2 interacts with host protein ACADM during the virus infectious cycle
                                                        

- (Peer Reviewed Journal)Vuono, E., Ramirez Medina, E., Silva, E.B., Berggren, K., Rai, A., Espinoza, N.N., Gladue, D.P., Borca, M.V. 2023. Classical swine fever virus structural glycoprotein E2 interacts with host protein ACADM during the virus infectious cycle. Viruses. 15(5). https://doi.org/10.3390/v15051036.Deletion of an African swine fever ATP-dependent RNA hel-icase QP509L from the highly virulent Georgia 2010 strain does not affect replication or virulence
                                                        

- (Peer Reviewed Journal)Ramirez Medina, E., Vuono, E., Pruitt, S., Rai, A., Espinoza, N.N., Spinard III, E.J., Valadares, A., Silva, E.B., Velazquez Salinas, L., Borca, M.V., Gladue, D.P. 2022. Deletion of an African swine fever ATP-dependent RNA hel-icase QP509L from the highly virulent Georgia 2010 strain does not affect replication or virulence. Viruses. 14(11). https://doi.org/10.3390/v14112548.The presence of virus neutralizing antibodies is highly associated with protection against virulent challenge in domestic pigs immunized with ASFV live attenuated vaccine candidates
                                                        

- (Peer Reviewed Journal)Silva, E.B., Krug, P., Ramirez Medina, E., Pruitt, S., Rai, A., Espinoza, N.N., Valadares, A., Gladue, D.P., Borca, M.V. 2022. The presence of virus neutralizing antibodies is highly associated with protection against virulent challenge in domestic pigs immunized with ASFV live attenuated vaccine candidates. Microbiology Resource Announcements. 11(11):1311. https://doi.org/10.3390/pathogens11111311.ASFV Gene A151R is involved in the process of virulence in domestic swine
                                                        

- (Peer Reviewed Journal)Ramirez Medina, E., Vuono, E., Pruitt, S., Rai, A., Espinoza, N.N., Valladres, A., Spinard Iii, E.J., Silva, E.B., Velazquez Salinas, L., Gladue, D.P., Borca, M.V. 2022. ASFV Gene A151R is involved in the process of virulence in domestic swine. Viruses. 14(8):1834. https://doi.org/10.3390/v14081834.Deletion of the ASFV dUTPase gene E165R from the genome of highly virulent African swine fever virus Georgia 2010 does not affect virus replication or virulence in domestic pigs
                                                        

- (Peer Reviewed Journal)Vuono, E., Ramirez Medina, E., Pruitt, S.E., Rai, A., Espinoza, N.N., Silva, E.B., Velazquez Salinas, L., Gladue, D.P., Borca, M.V. 2022. Deletion of the ASFV dUTPase gene E165R from the genome of highly virulent African swine fever virus Georgia 2010 does not affect virus replication or virulence in domestic pigs. Viruses. 14(7):1409. https://doi.org/10.3390/v14071409.Deletion of H108R reduces virulence of the Georgia strain of African swine fever virus with surviving animals being protected against virulent challenge
                                                        

- (Peer Reviewed Journal)Vuono, E., Ramirez Medina, E., Silva, E.B., Rai, A., Pruitt, S.E., Espinoza, N.N., Valladares, A., Velazquez Salinas, L., Gladue, D.P., Borca, M.V. 2022. Deletion of H108R reduces virulence of the Georgia strain of African swine fever virus with surviving animals being protected against virulent challenge. Journal of Virology. https://doi.org/10.1128/jvi.00545-22.Experimental infection of domestic pigs with an African swine fever virus field strain isolated in 2021 from the Dominican Republic
                                                        

- (Peer Reviewed Journal)Ramirez Medina, E., O'Donnell, V., Silva, E.B., Espinoza, N.N., Velazquez Salinas, L., Gladue, D.P., Borca, M.V. 2022. Experimental infection of domestic pigs with an African swine fever virus field strain isolated in 2021 from the Dominican Republic. Viruses.  https://doi.org/10.3390/v14051090.Identification of genetic deletions in ASFV that could be potentially used as targets for the development of DIVA vaccines
                                                        

- (Abstract Only)Vuono, E., Ramirez Medina, E., Silva, E.B., Rai, A., Pruitt, S.E., Espinoza, N.N., Velazquez Salinas, L., Borca, M.V., Gladue, D.P. 2022. Identification of genetic deletions in ASFV that could be potentially used as targets for the development of DIVA vaccines. Meeting Abstract. https://doi.org/10.1128/JVI.01419-21.Development of a novel African swine fever virus (ASFV) live attenuated vaccine candidate: deletion of A137R gene drastically attenuates Georgia strain and induce protection against the virulent challenge
                                                        

- (Peer Reviewed Journal)Gladue, D.P., Ramirez Medina, E., Vuono, E., Silva, E.B., Rai, A., Pruitt, S.E., Espinoza, N.N., Velazquez-Salinas, L., Borca, M.V. 2021. Development of a novel African swine fever virus (ASFV) live attenuated vaccine candidate: deletion of A137R gene drastically attenuates Georgia strain and induce protection against the virulent challenge. Journal of Virology.  https://doi.org/10.1128/JVI.01139-21.A cell culture-adapted vaccine virus against the current pandemic African swine fever virus strain
                                                        

- (Peer Reviewed Journal)Borca, M.V., Rai, A., Ramirez-Medina, E., Silva, E.B., Velazquez-Salinas, L., Vuono, E., Espinoza, N.N., Pruitt, S.E., Gladue, D.P. 2021. A cell culture-adapted vaccine virus against the current pandemic African swine fever virus strain. Nature Communications. https://doi.org/10.1128/JVI.00123-21.Leukocyte gene expression of dairy cattle in response to flooring type and additional substance P

- (Abstract Only)Eicher, S.D., Silva, E.B., Marchant-Forde, J.N., Schutz, M.M. 2018. Leukocyte gene expression of dairy cattle in response to flooring type and additional substance P. IN: Proceedings of the Society for Leukocyte Biology, October 14-16, 2018, Chandler, Arizona. p. 30.The effects of orally administered cortisol and norepinephrine on weanling piglet gut microbial populations and Salmonella passage

- (Peer Reviewed Journal)Acute brief heat stress in late gestation alters neonatal calf innate immune functions

- (Peer Reviewed Journal)Strong, R.A., Silva, E.B., Cheng, H., Eicher, S.D. 2015. Acute brief heat stress in late gestation alters neonatal calf innate immune functions. Journal of Dairy Science. 98:7771-7783. doi.org/10.3168/jds.2015-9591.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov