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                    U.S. DEPARTMENT OF AGRICULTURE
 Dietary Prevention of Obesity-related Disease Research: Grand Forks, ND
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ARS Home Plains Area Grand Forks, North Dakota Grand Forks Human Nutrition Research Center Dietary Prevention of Obesity-related Disease Research People & Locations







Bryan D Safratowich
                        Dietary Prevention of Obesity-related Disease Research

                        




                        
                        Biological Laboratory Technical
                        Phone: (701) 795-8185
                        
                        
                        Fax: (701) 795-8230(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            **Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Efficacy of butyrate to inhibit colonic cancer cell growth is cell type-specific and apoptosis-dependent
                                                        

- (Peer Reviewed Journal)Oncel, S., Safratowich, B.D., Lindlauf, J., Liu, Z., Palmer, D., Briske Anderson, M.J., Zeng, H. 2024. Efficacy of butyrate to inhibit colonic cancer cell growth is cell type-specific and apoptosis-dependent. Nutrients. 16(4). Article 529. https://doi.org/10.3390/nu16040529.Changes of the fecal metabolome accompany an increase in aberrant crypt foci in the colon of C57BL/6 mice fed a high-fat diet
                                                        

- (Peer Reviewed Journal)Zeng, H., Safratowich, B.D., Cheng, W., Magnuson, A.D., Picklo, M.J. 2022. Changes of the fecal metabolome accompany an increase in aberrant crypt foci in the colon of C57BL/6 mice fed a high-fat diet. Biomedicines. 10(11). Article 2891. https://doi.org/10.3390/biomedicines10112891.Identification of fecal oncogenic signatures in the inflammatory colon of C57BL/6 mice fed a high fat diet
                                                        

- (Peer Reviewed Journal)Zeng, H., Safratowich, B.D., Cheng, W., Bukowski, M.R. 2022. Identification of fecal oncogenic signatures in the inflammatory colon of C57BL/6 mice fed a high fat diet. Journal of Nutritional Biochemistry. 111. https://doi.org/10.1016/j.jnutbio.2022.109188.Deoxycholic acid modulates cell-junction gene expression and increases intestinal barrier dysfunction in Caco-2 cell monolayers
                                                        

- (Peer Reviewed Journal)Zeng, H., Safratowich, B.D., Cheng, W., Larson, K.J., Briske Anderson, M.J. 2022. Deoxycholic acid modulates cell-junction gene expression and increases intestinal barrier dysfunction in Caco-2 cell monolayers. Molecular Nutrition and Food Research. https://doi.org/10.3390/molecules27030723.Adequacy of calcium and vitamin D reduces inflammation, beta-catenin signaling and dysbiotic Parasutterela bacteria in the colon of C57BL/6 mice fed a Western-style diet
                                                        

- (Peer Reviewed Journal)Zeng, H., Safratowich, B.D., Liu, Z., Bukowski, M.R., Ishaq, S. 2021. Adequacy of calcium and vitamin D reduces inflammation, beta-catenin signaling and dysbiotic Parasutterela bacteria in the colon of C57BL/6 mice fed a Western-style diet. Journal of Nutritional Biochemistry. 92. Article 108613. https://doi.org/10.1016/j.jnutbio.2021.108613.Superior inhibitory efficacy of butyrate over propionate and acetate against human colon cancer cell proliferation via cell cycle arrest and apoptosis
                                                        

- (Peer Reviewed Journal)Zeng, H., Hamlin, S.K., Safratowich, B.D., Cheng, W., Johnson, L.K. 2020. Superior inhibitory efficacy of butyrate over propionate and acetate against human colon cancer cell proliferation via cell cycle arrest and apoptosis. Nutrition Research. 83:63-72. https://doi.org/10.1016/j.nutres.2020.08.009.Butyrate inhibits deoxycholic-acid-resistant colonic cell proliferation via cell cycle arrest and apoptosis
                                                        

- (Peer Reviewed Journal)Zeng, H., Safratowich, B.D., Wang, T.T., Hamlin, S., Johnson, L. 2020. Butyrate inhibits deoxycholic-acid-resistant colonic cell proliferation via cell cycle arrest and apoptosis. Molecular Nutrition and Food Research. https://doi.org/10.1002/mnfr.201901014.Advanced liver steatosis accompanies an increase in hepatic inflammation, colonic secondary bile acids and Lactobacillaceae/Lachnospiraceae bacteria in C57BL/6 mice fed a high-fat diet
                                                        

- (Peer Reviewed Journal)Zeng, H., Larson, K.J., Cheng, W., Bukowski, M.R., Safratowich, B.D., Liu, Z., Hakkak, R. 2020. Advanced liver steatosis accompanies an increase in hepatic inflammation, colonic secondary bile acids and lactobacillaceae/lachnospiraceae bacteria in C57BL/6 mice fed a high-fat diet. Journal of Nutritional Biochemistry. https://doi.org/10.1016/j.jnutbio.2019.108336.


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