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 Diet, Genomics and Immunology Laboratory: Beltsville, MD
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ARS Home Northeast Area Beltsville, Maryland (BHNRC) Beltsville Human Nutrition Research Center Diet, Genomics and Immunology Laboratory People & Locations







Allen D Smith
                        Diet, Genomics and Immunology Laboratory

                        




                        
                        Research Virologist
                        Phone: (301) 504-8577
                         ext. 280
                        
                        Fax: (301) 504-9062(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsDefining the Impact of Different Foods or Their Components, in the Context of A Western-Style Diet, on Gut Health
                                                    In-House Appropriated
                                                                    (D)Accession Number: 443596Impact of Genetics, Growing Condition or Processing on Bioactive Components in Coffee and Microgreens: Influences on Health
                                                    In-House Appropriated
                                                                    (D)Accession Number: 445803Glycoprofiling of Oligosaccharides in Foods
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 443166**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)A type 4 resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data
                                                        

- (Peer Reviewed Journal)Smith, A.D., Chen, C.T., Cheung, L., Ward, R., Jones, B., Pletsch, E.A., Dawson, H.D. 2024. A type 4 resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data. Nutrients. 15,3141-3157.  https://doi.org/10.1039/d3fo04512a.Multi-omics analysis detected multiple pathways by which pomegranate punicalagin exerts its biological effects in modulating host–microbiota interactions in murine colitis models
                                                        

- (Peer Reviewed Journal)Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Yang, H., Li, R.W. 2023. Multi-omics analysis detected multiple pathways by which pomegranate punicalagin exerts its biological effects in modulating host–microbiota interactions in murine colitis models. Food & Function. 14:3824. https://doi.org/10.1039/D3FO00286A.Ellagitannin punicalagin disrupts the pathways related to bacterial growth and affects multiple pattern recognition receptor signaling by acting as a selective histone deacetylase inhibitor
                                                        

- (Peer Reviewed Journal)Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Yang, H., Li, R.W. 2023. Ellagitannin punicalagin disrupts the pathways related to bacterial growth and affects multiple pattern recognition receptor signaling by acting as a selective histone deacetylase inhibitor. Journal of Agricultural and Food Chemistry. 71(12):5016-5026. https://doi.org/10.1021/acs.jafc.2c08738.Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium
                                                        

- (Peer Reviewed Journal)Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Cheung, L., Yang, H., Li, R.W. 2022. Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium. Food & Function. 14(2):1048-1061. https://doi.org/10.1039/D2FO02873E.Raw potato starch alters the microbiome, colon and cecal gene expression, and resistance to citrobacter rodentium infection in mice fed a western diet
                                                        

- (Peer Reviewed Journal)Smith, A.D., Chen, C.T., Cheung, L., Dawson, H.D. 2023. Raw potato starch alters the microbiome, colon and cecal gene expression, and resistance to citrobacter rodentium infection in mice fed a western diet. Frontiers in Nutrition. 9:2022. https://doi.org//10.3389/fnut.2022.1057318.Resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data
                                                        

- (Peer Reviewed Journal)Smith, A.D., Chen, C.T., Cheung, L., Ward, R., Hintze, K., Dawson, H.D. 2022. Resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data. Frontiers in Nutrition. 9. Article 782667. https://doi.org/10.3389/fnut.2022.782667.IL-25 treatment improves metabolic syndrome in high fat diet and genetic models of obesity
                                                        

- (Peer Reviewed Journal)Smith, A.D., Fan, A.X., Qin, B., Desai, N., Zhao, A., Shea-Donohue, T. 2021. IL-25 treatment improves metabolic syndrome in high-fat diet and genetic models of obesity. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 14:4875-4887. https://doi.org/10.2147/DMSO.S335761.Dietary Indole-3-carbinol alleviated spleen enlargement, enhanced IgG response in C3H/HeN mice infected with Citrobacter rodentium
                                                        

- (Peer Reviewed Journal)Wu, Y., Wang, J., He, Q., Yu, L., Pham, Q., Cheung, L., Zhang, Z., Kim, Y.S., Smith, A.D., Wang, T.T. 2020. Dietary Indole-3-carbinol alleviated spleen enlargement, enhanced IgG response in C3H/HeN mice infected with Citrobacter rodentium. Nutrients. 12(10)3148. https://doi.org/10.3390/nu12103148.Mechanistic insights into the attenuation of intestinal inflammation and modulation of the gut microbiome by krill oil using in vitro and in vivo models
                                                        

- (Peer Reviewed Journal)Liu, F., Smith, A.D., Solano Aguilar, G., Wang, T.T., Pham, Q., Tang, Q., Urban Jr, J.F., Xue, C., Li, R.W. 2020. Mechanistic insights into the attenuation of intestinal inflammation and modulation of the gut microbiome by krill oil using in vitro and in vivo models. Microbiome. 8:83. https://doi.org/10.1186/s40168-020-00843-8.Indole-3-carbinol inhibits Citrobacter rodentium infection through multiple pathways including reduction of bacterial adhesion and enhancement of cytotoxic T cell activity
                                                        

- (Peer Reviewed Journal)Wu, Y., He, Q., Yu, L., Pham, Q., Cheung, L., Kim, Y.S., Wang, T.T., Smith, A.D. 2020. Indole-3-carbinol inhibits Citrobacter rodentium infection through multiple pathways including reduction of bacterial adhesion and enhancement of cytotoxic T cell activity. Nutrients. 12(4):917. https://doi.org/doi: 10.3390/nu12040917.Potentiation of IL-4 signaling by retinoic acid in intestinal epithelial cells and macrophages - mechanisms and targets
                                                        

- (Peer Reviewed Journal)Chen, C.T., Smith, A.D., Cheung, L., Pham, Q., Urban Jr, J.F., Dawson, H.D. 2020. Potentiation of IL-4 signaling by retinoic acid in intestinal epithelial cells and macrophages - mechanisms and targets. Frontiers in Immunology. 10.3389. https://doi.org/10.3389/fimmu.2020.00605.Pomegranate peel extract reduced the pathogenicity of Citrobacter rodentium-infections in mice
                                                        

- (Peer Reviewed Journal)Smith, A.D., George, N.S., Cheung, L., Bhagavathy, G.V., Luthria, D.L., John, K.M., Bhagwat, A.A. 2020. Pomegranate peel extract reduced the pathogenicity of Citrobacter rodentium-infections in mice. Nutrition Research. 73:27-37. https://doi.org/doi:10.1016/j.nutres.2019.11.001.Pomegranate peel extract alters the microbiome in mice and dysbiosis caused by Citrobacter rodentium infection
                                                        

- (Peer Reviewed Journal)George, N.S., Cheung, L., Luthria, D.L., Santin, M., Dawson, H.D., Bhagwat, A.A., Smith, A.D. 2019. Pomegranate peel extract alters the microbiome in mice and dysbiosis caused by Citrobacter rodentium infection. Journal of Food Science and Nutrition. https://doi.org/10.1002/fsn3.1106.The regulatory actions of retinoic acid on M2 polarization of porcine macrophages
                                                        

- (Peer Reviewed Journal)Chen, C.T., Perry, T.L., Chitko-Mckown, C.G., Smith, A.D., Cheung, L., Beshah, E., Urban Jr, J.F., Dawson, H.D. 2019. The regulatory actions of retinoic acid on M2 polarization of porcine macrophages. Developmental and Comparative Immunology. 98(9):20-23. https://doi.org/10.1016/j.dci.2019.03.020.Impact of micronutrients on the immune response of animals
                                                        

- (Review Article)Smith, A.D., Panickar, K.S., Urban Jr, J.F., Dawson, H.D. 2018. Impact of micronutrients on the immune response of animals. Annual Review of Animal Biosciences. 6:227-254. https://doi.org/10.1146/annurev-animal-022516-022914.ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production
                                                        

- (Peer Reviewed Journal)Damie, S.R., Martin, R.K., Cockburn, C.L., Lownik, J.C., Carlyon, J.A., Smith, A.D., Conrad, D.H. 2017. ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production. Allergy. 148(4):542-551. https://doi.org//101111/a11.13261.Bidirectional brain-gut interactions and chronic pathological changes after traumatic brain injury in mice

- (Peer Reviewed Journal)Ma, E.L., Smith, A.D., Desai, N., Cheung, L., Hanscom, M., Stoica, B.A., Loane, D.J., Shea-Donohue, T., Faden, A.I. 2017. Bidirectional brain-gut interactions and chronic pathological changes after traumatic brain injury in mice. Brain Behavior and Immunity. pii: S0889-1591(17)30207-6. doi: 10.1016/j.bbi.2017.06.018.Transcriptomic analysis of swarm motility phenotype of Salmonella enterica serovar Typhimurium mutant defective in periplasmic glucan synthesis

- (Peer Reviewed Journal)Bhagwat, A.A., Young, L., Smith, A.D., Bhagwat, M. 2017. Transcriptomic analysis of swarm motility phenotype of Salmonella enterica serovar Typhimurium mutant defective in periplasmic glucan synthesis. Current Microbiology. doi:10.1007/s00284-017-1267-1.Parasites, nutrition, immune responses, and biology of metabolic tissues

- (Review Article)Shea-Donohue, T., Qin, B., Smith, A.D. 2017. Parasites, nutrition, immune responses, and biology of metabolic tissues. Parasite Immunology. 39(5). doi: 10.1111/pim.12422An in-depth comparison of the porcine, murine and human inflammasomes; lessons from the porcine genome and transcriptome

- (Peer Reviewed Journal)Dawson, H.D., Smith, A.D., Chen, C.T., Urban Jr, J.F. 2016. An in-depth comparison of the porcine, murine and human inflammasomes; lessons from the porcine genome and transcriptome. Veterinary Microbiology. pii:S0378-1135(16)30137-7. doi: 10.1016/j.vetmic.2016.05.013.Acidic Chitinase Limits Allergic Inflammation and Promotes Intestinal Nematode Expulsion

- (Peer Reviewed Journal)Vannella, K.M., Ramalingam, T.R., De Queiroz, P.R., Sciurba, J., Barron, L., Borthwick, L., Smith, A.D., Mentink-Kane, M., White, S., Thompson, R.W., Cheever, A.W., Bock, K., Moore, I., Fitz, L.J., Urban Jr, J.F., Wynn, T.A. 2016. Acidic Chitinase Limits Allergic Inflammation and Promotes Intestinal Nematode Expulsion. Nature Immunology. 17(5):538-44 doi: 101038/ni.3417.Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of nippostrongylus brasiliensis through induction of Th2 cytokines

- (Peer Reviewed Journal)Mclean, L.P., Smith, A.D., Cheung, L., Urban Jr, J.F., Sun, R., Grinchuk, V., Dasai, Zhao, A., Raufman, J.P., Shea-Donohue, T. 2016. Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of nippostrongylus brasiliensis through induction of Th2 cytokines. American Journal of Physiology - Gastrointestinal and Liver Physiology. 311(1):G130-141. doi: 10.1152/ajpgi.00461.2014.Understanding the host-adapted state of Citrobacter rodentium by transcriptomic analysis

- (Peer Reviewed Journal)Smith, A.D., Yan, X., Chen, C.T., Dawson, H.D., Bhagwat, A.A. 2016. Understanding the host-adapted state of Citrobacter rodentium by transcriptomic analysis. Archives Of Microbiology. 198:353-362.IL-25 or IL-17E protects against high-fat diet-induced hepatic steatosis in mice dependent upon IL-13 activation of STAT6

- (Peer Reviewed Journal)Wang, A., Yang, Z., Grinchuk, V., Smith, A.D., Qin, B., Lu, N., Wang, D., Wang, H., Ramalingam, T.R., Wynn, T.A., Urban Jr, J.F., Shea-Donohue, T., Zhao, A. 2015. IL-25 or IL-17E protects against high-fat diet-induced hepatic steatosis in mice dependent upon IL-13 activation of STAT6. Journal of Immunology. 195(10): 4771-4780. doi:10.4049/jimmunol.1500337.Immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis

- (Peer Reviewed Journal)Fricke, F.W., Song, Y., Wang, A., Smith, A.D., Grinchuk, V., Mongodin, E., Pei, C., Ma, B., Lu, N., Urban Jr, J.F., Shea-Donohue, T. 2015. Immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis. BMC Microbiome. doi: 10.1186/S40168-015-0103-8.Swarm and swim motilities of Salmonella enterica serovar Typhimurium and role of osmoregulated periplasmic glucans

- (Peer Reviewed Journal)Dharne, M., Kannan, P., Murphy, C.F., Smith, A.D., Bhagwat, A.A. 2015. Swarm and swim motilities of Salmonella enterica serovar Typhimurium and role of osmoregulated periplasmic glucans. Microbiology Discovery. 3:3.Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium

- (Peer Reviewed Journal)Mclean, L.P., Smith, A.D., Cheung, L., Sun, R., Grinchuk, V., Vanuytsel, T., Desai, N., Urban Jr, J.F., Zhao, A., Raufman, J.P., Shea-Donohue, T. 2015. Type 3 Muscarinic Receptors Contribute to Clearance of Citrobacter rodentium. Inflammatory Bowel Diseases. DOI: 10.1097/MIB.0000000000000408.Swarm motility of Salmonella enterica serovar Typhimurium is inhibited by compounds from fruit peel extracts

- (Peer Reviewed Journal)Mahadwar, G., Chauhan, K.R., Bhagavathy, G., Murphy, C.F., Smith, A.D., Bhagwat, A.A. 2015. Swarm motility of Salmonella enterica serovar Typhimurium is inhibited by compounds from fruit peel extracts. Letters in Applied Microbiology. 60:334-340.Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice

- (Peer Reviewed Journal)Wang, A., Smith, A.D., Li, Y., Urban Jr, J.F., Thirumalai, R.R., Wynn, T., Lu, N., Shea-Donohue, T., Yang, Z., Zhao, A. 2014. Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice. Cell & Bioscience. DOI: 10.1186/2045-3701-4-72.Evaluation of ribosomal RNA removal protocols for Salmonella RNA-Seq projects

- (Peer Reviewed Journal)Bhagwat, A., Z Ying, I., Smith, A. 2013. Evaluation of ribosomal RNA removal protocols for Salmonella RNA-Seq projects. Advances in Microbiology. 4:25-32.Determining RNA quality for NextGen sequencing: some exceptions to the gold standard rule of 23S to 16S rRNA ratio

- (Peer Reviewed Journal)Bhagwat, A.A., Ying, I., Karns, J.S., Smith, A.D. 2013. Determining RNA quality for NextGen sequencing: some exceptions to the gold standard rule of 23S to 16S rRNA ratio. Advances in Microbiology. 1:10.Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity

- (Peer Reviewed Journal)Yang, Z., Grinchuk, V., Smith, A.D., Qin, B., Bohl, J.A., Sun, R., Notari, L., Zhang, Z., Sesaki, H., Urban Jr, J.F., Shea-Donahue, T., Zhao, A. 2013. Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity. Infection and Immunity. 81(6):1905-1914.Selenium status alters the immune response and expulsion of adult Heligmosomodies bakeri in mice

- (Peer Reviewed Journal)Smith, A.D., Cheung, L., Shea-Donohue, T., Urban Jr, J.F. 2013. Selenium status alters the immune response and expulsion of adult Heligmosomodies bakeri in mice. Infection and Immunity. 81(7):2546-2553.Hypervirulent- host-associated Citrobacter rodentium cells have poor acid tolerance

- (Peer Reviewed Journal)Smith, A.D., Bhagwat, A.A. 2013. Hypervirulent- host-associated Citrobacter rodentium cells have poor acid tolerance. Current Microbiology. 66(5):522-526.Role of anionic charges of osmoregulated periplasmic glucans of Salmonella enterica Serovar Typhimurium SL1344 in mice virulence

- (Peer Reviewed Journal)Bhagwat, A.A., Kannan, P., Leow, Y., Dharne, M., Smith, A.D. 2012. Role of anionic charges of osmoregulated periplasmic glucans of Salmonella enterica Serovar Typhimurium SL1344 in mice virulence. Archives Of Microbiology. 194(6):541-548.Long-term selenium deficiency increases the pathogenicity of a Citrobacter rodentium infection in mice

- (Peer Reviewed Journal)Smith, A.D., Cheung, L., Botero, S. 2011. Long-term selenium deficiency increases the pathogenicity of a Citrobacter rodentium infection in mice. Biological Trace Element Research. Available: dx.doi.org/10.1007/S12011-011-9071-4.The pathogenicity of an enteric Citrobacter rodentium infection is enhanced by deficiencies in the antioxidants selenium and vitamin E

- (Peer Reviewed Journal)Smith, A.D., Botero, S., Shea-Donohue, T., Urban Jr, J.F. 2011. The pathogenicity of an enteric Citrobacter rodentium infection is enhanced by deficiencies in the antioxidants selenium and vitamin E. Infection and Immunity. 79:1471-1478.Enteric pathogens and gut function: role of cytokines and STATs

- (Peer Reviewed Journal)Shea-Donohue, T., Fasano, A., Smith, A.D., Zhao, A. 2010. Enteric pathogens and gut function: role of cytokines and STATs. Gut Microbes. 1(5):316-324.Osmoregulated periplasmic glucans synthesis gene family of Shigella flexneri

- (Peer Reviewed Journal)Liu, L., Dharne, M., Kannan, P., Smith, A.D., Meng, J., Fan, M., Boren, T., Ranallo, R., Bhagwat, A.A. 2010. Osmoregulated periplasmic glucans synthesis gene family of Shigella flexneri. Archives Of Microbiology. 192(3):167-174.Motility revertants of opgGH mutants of Salmonella enterica serovar Typhimurium remain defective in mice virulence

- (Peer Reviewed Journal)Kannan, P., Dharne, M., Smith, A.D., Karns, J.S., Bhagwat, A.A. 2009. Motility revertants of opgGH mutants of Salmonella enterica serovar Typhimurium remain defective in mice virulence. Current Microbiology. 59(6):641-645.Osmoregulated periplasmic glucans are needed for competitive growth and biofilm formation by Salmonella enterica serovar Typhimurium in leafy-green vegetable wash-waters and colonization in mice

- (Peer Reviewed Journal)Liu, L., Tan, S., Jun, W., Smith, A.D., Meng, J., Bhagwat, A.A. 2008. Osmoregulated periplasmic glucans are needed for competitive growth and biofilm formation by Salmonella enterica serovar Typhimurium in leafy-green vegetable wash-waters and colonization in mice. FEMS Microbiology Letters. 292:13-20.Characterization of Salmonella isolates from retail foods based on serotyping, pulse field gel electrophoresis, antibiotic resistance and other phenotypic properties

- (Peer Reviewed Journal)Xia, X., Zhao, S., Smith, A.D., Mcevoy, J.L., Jianghong, M., Bhagwat, A.A. 2009. Characterization of Salmonella isolates from retail foods based on serotyping, pulse field gel electrophoresis, antibiotic resistance and other phenotypic properties. International Journal of Food Microbiology. 129:93-98.Osmoregulated periplasmic glucans of Salmonella enterica serovar Typhimurium are required for optimal virulence in mice

- (Peer Reviewed Journal)Bhagwat, A.A., Jun, W., Liu, L., Porteen, K., Dharne, M., Pheh, B., Tall, B.D., Kothary, M.H., Gross, K.C., Angle, S., Jianghong, M., Smith, A.D. 2009. Osmoregulated periplasmic glucans of Salmonella enterica serovar Typhimurium are required for optimal virulence in mice. Microbiology. 155:229-237.Copper deficiency increases the virulence of amyocarditic and myocarditic strains of cocksackievirus B3 in Mice

- (Peer Reviewed Journal)Smith, A.D., Botero, S., Levander, O. 2008. Copper deficiency increases the virulence of amyocarditic and myocarditic strains of cocksackievirus B3 in mice. Journal of Nutrition. 138(5):849-55.Intestinal inflammation caused by magnesium deficiency alters basal and oxidative stress-induced intestinal function

- (Peer Reviewed Journal)Scanlan, B.J., Tuft, B., Elfrey, J.E., Smith, A., Zhao, A., Morimoto, M., Chmielinska, J.J., Tejero-Taldo, M.I., Mak, I.T., Weglicki, W.B., and Shea-Donohue, T. 2007. Intestinal inflammation caused by magnesium deficiency alters basal and oxidative stress-induced intestinal function.  Molecular and Cellular Biochemistry. Jul27;[Epub ahead of print].Selenium (Se) deficiency alters intestinal diaphorase activity in mice infected with the intestinal parasitic worm Heligmosomoides polygyrus

- (Abstract Only)Urban Jr, J.F., Smith, A.D., Botero, S., Dawson, H.D., Anthony, R., Gause, W., Shea-Donohue, T. 2007. Selenium (Se) deficiency alters intestinal diaphorase activity in mice infected with the intestinal parasitic worm Heligmosomoides polygyrus. Experimental Biology.COPPER DEFICIENCY INCREASES THE VIRULENCE OF COXSACKIEVIRUS B3 INFECTIONS IN MICE.

- (Abstract Only)Smith, A.D., Botero, S., Levander, O.A. 2006. Copper deficiency increases the virulence of coxsackievirus B3 infections in mice [abstract]. Federation of American Societies for Experimental Biology Conference. 20(4):A554.GLUTATHIONE IS REQUIRED FOR EFFICIENT PRODUCTION OF INFECTIOUS PICORNAVIRUSES VIRIONS

- (Peer Reviewed Journal)Smith, A.D., Dawson, H.D. 2006. Glutathione is required for efficient production of infectious picornavirus virions. Electronic Virology. Available: http://www.sciencedirect.com/EFFECT OF PHYSICAL RESTRAINT ON OXIDATIVE STRESS IN MICE FED A SELENIUM AND VITAMIN E DEFICIENT DIET

- (Peer Reviewed Journal)South, P.K., Smith, A.D., Guidry, C.A., Levander, O.A. 2006. Effect of physical restraint on oxidative stress in mice fed a selenium and vitamin E deficient diet. Biological Trace Element Research. 109(3):293-300.EFFECT OF PHYSICAL RESTRAINT ON OXIDATIVE STRESS IN MICE FED A SELENIUM AND VITAMIN E DEFICIENT DIET

- (Abstract Only)South, P., Smith, A.D., Guidry, C.A., Levander, O.A. 2006. Effect of physical restraint on oxidative stress in mice fed a selenium and vitamin e deficient diet[abstract].  Biological Trace Element Research. 109(3):293-300.PRETREATMENT OF HELA CELLS WITH THE GLUTATHIONE SYNTHESIS INHIBITOR, L-BUTHIONINE-SULFOXIMINE (BSO), INHIBITS REPLICATION OF PICORNAVIRUSES

- (Abstract Only)Smith, A.D. 2005. Pretreatment of hela cells with the glutathione synthesis inhibitor, l-buthionine-sulfoximine (bso), inhibits replication of picornaviruses. Federation of American Societies for Experimental Biology Conference.EFFECT OF SELENIUM AND/OR VITAMIN E DEFICIENCIES ON HELIGMOSOMOIDES POLYGYRUS INFECTIONS IN MICE

- (Peer Reviewed Journal)Smith, A.D., Madden, K. B., Au Yeung, K., Zhao, A., Elfrey, J., Finkelman, F., Levander, O.A., Shea Donohue, P.T., and Urban Jr, J.F. 2005. Effect of selenium and/or vitamin E deficiencies on Heligmosomoides polygyrus infections in mice. Journal of Nutrition.  135:830-836.IMPACT OF VITAMIN E OR SELENIUM DEFICIENCY ON NEMATODE-INDUCED ALERATIONS IN MURINE INTESTINAL FUNCTION

- (Peer Reviewed Journal)Auyeung, K., Smith, A.D., Zhao, A., Madden, K., Elfrey, J., Sullivan, C., Levander, O.A., Urban Jr, J.F., Shea Donohue, P.T. 2005. Impact of vitamin E or selenium deficiency on nematode-induced alerations in murine intestinal function. Experimental Parasitology.  109:201-208.MEMBRANE-DERIVED OLIGOSACCHARIDES OF SALMONELLA ENTERICA SEROVAR TYPHIMURIUM

- (Abstract Only)Jun, W., Bhagwat, A.A., Gross, K.C., Smith, A.D., Angle, S.J. 2004. Membrane-derived oligosaccharides of Salmonella enterica serovar Typhimurium. American Society for Microbiology Annual Meeting. p. 107.SELENIUM (SE) AND VITAMIN E (VE) DEFICIENCIES IMPAIR INTESTINAL FUNCTION AND RESULT IN PERSISTENT INFECTION WITH HELIGMOSOMOIDES POLYGYRUS

- (Abstract Only)Smith, A.D., Madden, K., Zhao, A., Auyeung, K., Levander, O.A., Finkelman, F., Urban Jr, J.F., Shea Donohue, P.T. 2004. Selenium (se) and vitamin E (ve) deficiencies impair intestinal function and result in persistent infection with heligmosomoides polygyrus [abstract]. Federation of American Society of Experimental Biology Journal. 18(4):A9.STUDY OF THE EFFECT OF COPPER DEFICIENCY ON CVB3/0 AND CVB3/20 INFECTIONS:  THE LIGHT MICROSCOPIC EVALUATION OF THE PANCREATA AND HEARTS OF C3H/HEJ MICE

- (Abstract Only)Nelva, B., Levander, O.A., Hines, F., Smith, A.D. 2004. Study of the effect of copper deficiency on cvb3/0 and cvb3/20 infections:  The light microscopic evaluation of the pancreata and hearts of c3h/hej mice [abstract]. Toxicologic Pathology. 32(1):146.CRYSTAL STRUCTURE OF A HUMAN RHINOVIRUS TYPE 14 (HRV14):  HUMAN IMMUNO-    DEFICIENCY VIRUS TYPE 1 (HIV-1) V3 LOOP CHIMERIC VIRUS THAT INDUCES        NEUTRALIZING ANTIBODIES AGAINST HIV-1.

- (Peer Reviewed Journal)Ding, J., Smith, A.D., Geisler, S., Arnold, G., Arnold, E. 2002. Crystal structure of a human rhinovirus type 14 (hrv14):  human immuno-    deficiency virus type 1 (hiv-1) v3 loop chimeric virus that induces        neutralizing antibodies against hiv-1.. Structure.EFFECTS OF DIETARY IRON OVERLOAD ON GLUTATHIONE PEROXIDASE KNOCK-OUT MICE

- (Peer Reviewed Journal)South, P., Levander, O.A., Smith, A.D. 2002. Effects of dietary iron overload on glutathione peroxidase knock-out mice. Biological Trace Element Research.EFFECT OF GOLD (I) COMPOUNDS ON THE VIRULENCE OF AN AMYOCORDITIC STRAIN OF COXSACKIEVIRUS

- (Peer Reviewed Journal)Smith, A.D., South, P.K., Levander, O.A. 2001. Effect of gold (i) compounds on the virulence of an amyocorditic strain of coxsackievirus. Biological Trace Element Research.HIGH THROUGHPUT 96-WELL MICROPLATE ASSAY FOR DETERMINING THE SPECIFIC      ACTIVITIES OF GLUTATHIONE PEROXIDASE AND THIOREDOXIN REDUCTASE

- (Book / Chapter)Smith, A.D., Levander, O.A. 2002. High throughput 96-well microplate assay for determining the specific      activities of glutathione peroxidase and thioredoxin reductase. Methods in Enzymology.


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