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                    U.S. DEPARTMENT OF AGRICULTURE
 Infectious Bacterial Diseases Research: Ames, IA
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ARS Home Midwest Area Ames, Iowa National Animal Disease Center Infectious Bacterial Diseases Research People & Locations







Jennifer  Wilson-Welder
                        Infectious Bacterial Diseases Research

                        




                        
                        Research Microbiologist
                        Phone: (515) 337-7765
                        
                        
                        Fax: (515) 337-7716(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsIntervention Strategies for Spirochete Diseases
                                                    In-House Appropriated
                                                                    (D)Accession Number: 441160**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Antimicrobial, preservative, and hazard assessments from eight chemical classes
                                                        

- (Peer Reviewed Journal)Hart-Cooper, W.M., Orts, W.J., Lynn, L.E., Scholes, R.C., Kim, J., Wilson-Welder, J.H. 2024. Antimicrobial, preservative, and hazard assessments from eight chemical classes. ACS Sustainable Chemistry & Engineering. 9:17869-17877. https://doi.org/10.1021/acsomega.3c08672.Correlation of lesion severity with bacterial changes in Treponeme-Associated Hoof Disease from free-roaming wild elk (Cervus canadensis)
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Han, S., Bayles, D., Alt, D.P., Kanipe, C.R., Garrison, K., Mansfield, K., Olsen, S.C. 2024. Correlation of lesion severity with bacterial changes in Treponeme-Associated Hoof Disease from free-roaming wild elk (Cervus canadensis). Animal Microbiome. https://doi.org/10.1186/s42523-024-00304-9.First molecular confirmation of Treponema spp. in lesions consistent with digital dermatitis in Chilean dairy cattle
                                                        

- (Peer Reviewed Journal)Canales, N., Bustamante, H., Wilson-Welder, J.H., Thomas, C., Ramirez, E., Salgado, M. 2022. First molecular confirmation of Treponema spp. in lesions consistent with digital dermatitis in Chilean dairy cattle. Pathogens. https://doi.org/10.3390/pathogens11050510.Lesion material from Treponema-associated Hoof Disease of wild elk induces disease pathology in the sheep Digital Dermatitis model
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Olsen, S.C., Alt, D.P., Bayles, D.O., Han, S., Mansfield, K. 2022. Lesion material from Treponema-associated Hoof Disease of wild elk induces disease pathology in the sheep Digital Dermatitis model. Frontiers in Veterinary Science. 8. Article 782149. https://doi.org/10.3389/fvets.2021.782149.A pseudomolecule assembly of the Rocky Mountain elk genome
                                                        

- (Peer Reviewed Journal)Masonbrink, R.E., Alt, D.P., Bayles, D.O., Boggiatto, P.M., Edwards, H., Tatum, F.M., Williams, J.E., Wilson-Welder, J.H., Wood, M., Zimin, A., Severin, A., Olsen, S.C. 2021. A pseudomolecule assembly of the Rocky Mountain elk genome. PLoS ONE. 16(4). https://doi.org/10.1371/journal.pone.0249899.Bovine immune response to vaccination and infection with Leptospira borgpetersenii serovar Hardjo
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Alt, D.P., Nally, J.E., Olsen, S.C. 2021. Bovine immune response to vaccination and infection with Leptospira borgpetersenii serovar Hardjo. mSphere. 6(2). https://doi.org/10.1128/mSphere.00988-20.Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Boggiatto, P.M., Nally, J.E., Wafa, E.I., Alt, D.P., Hornsby, R.L., Frank, A.T., Jones, D.E., Olsen, S.C., Bowden, N.B., Salem, A.K. 2020. Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms. Vaccine. 38(18):3464-3473. https://doi.org/10.1016/j.vaccine.2020.02.086.Further inquiry into the etiology of hoof disease in elk using bacterial metagenomics analysis

- (Abstract Only)Short communication: Lymphocyte proliferative responses in cattle naturally infected with digital dermatitis consists of CD8+ and gamma delta T cells but lack CD4+ T cells
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Nally, J.E., Alt, D.P., Humphrey, S.B., Olsen, S.C. 2018. Short communication: Lymphocyte proliferative responses in cattle naturally infected with digital dermatitis consists of CD8plus and gamma delta T cells but lack CD4plus T cells. Journal of Dairy Science. 101(9):8301-8307. https://doi.org/10.3168/jds.2017-13913.Isolation and characterization of pathogenic leptospires associated with cattle
                                                        

- (Peer Reviewed Journal)Nally, J.E., Hornsby, R.L., Alt, D.P., Bayles, D.O., Wilson-Welder, J.H., Bauer, N.E. 2018. Isolation and characterization of pathogenic leptospires associated with cattle. Veterinary Microbiology. 218:25-30. https://doi.org/10.1016/j.vetmic.2018.03.023.Inbred rats as a model to study persistent renal colonization and associated cellular immune responsiveness
                                                        

- (Peer Reviewed Journal)Nally, J.E., Wilson-Welder, J.H., Hornsby, R.L., Palmer, M.V., Alt, D.P. 2018. Inbred rats as a model to study persistent renal colonization and associated cellular immune responsiveness. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2018.00066.Experimental transmission of bovine digital dermatitis to sheep: development of an infection model.
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Nally, J.E., Alt, D.P., Palmer, M.V., Cotaney, J., Plummer, P. 2017. Experimental transmission of bovine digital dermatitis to sheep: development of an infection model. Veterinary Pathology. 55(2):245-257. https://doi.org/10.1177/0300985817736572.Treponeme-associated hoof disease of wild elk (Cervus elaphus spp.) in southwestern Washington State, USA
                                                        

- (Peer Reviewed Journal)Han, S., Mansfield, K., Haldorson, G., Bradway, D., Besser, T., Reed, D., Alt, D.P., Wilson-Welder, J.H. 2018. Treponeme-associated hoof disease of wild elk (Cervus elaphus spp.) in southwestern Washington State, USA. Veterinary Pathology. https://doi.org/10.1177/0300985818798108.Immunogenicity and efficacy of a rough Brucella suis vaccine delivered orally or parenterally to feral swine

- (Peer Reviewed Journal)Olsen, S.C., Wilson-Welder, J.H., Nol, P., Rhyan, J., Srirangathan, N. 2017. Immunogenicity and efficacy of a rough Brucella suis vaccine delivered orally or parenterally to feral swine. International Journal of Vaccine Research. 2(1): 6.Defective anti-polysaccharide IgG vaccine responses in IgA deficient mice
                                                        

- (Peer Reviewed Journal)Furuya, Y., Kirimanjeswara, G., Roberts, S., Racine, R., Wilson-Welder, J.H., Sanfilippo, A., Salmon, S., Metzger, D.W. 2017. Defective anti-polysaccharide IgG vaccine responses in IgA deficient mice. Vaccine. 35(37):4997-5005. https://doi.org/10.1016/j.vaccine.2017.07.071.Interaction of bovine peripheral blood polymorphonuclear cells and Leptospira species; innate responses in the natural bovine reservoir host.

- (Peer Reviewed Journal)Wilson-Welder, J.H., Frank, A.T., Hornsby, R.L., Olsen, S.C., Alt, D.P. 2016. Interaction of bovine peripheral blood polymorphonuclear cells and Leptospira species; innate responses in the natural bovine reservoir host. Frontiers in Microbiology. 7:1110.Digital dermatitis in cattle: current bacterial and immunological findings

- (Peer Reviewed Journal)Wilson-Welder, J.H., Alt, D.P., Nally, J.E. 2015. Digital dermatitis in cattle: current bacterial and immunological findings. Animals. 5:114-1135. doi: 10.3390/ani5040400.Complete genome sequence of Leptospira interrogans serovar Bratislava, strain PigK151

- (Peer Reviewed Journal)Alt, D.P., Wilson-Welder, J.H., Bayles, D.O., Cameron, C., Adler, B., Bulach, D.M., Seemann, T., Lehane, M.J., Haines, L.R., Darby, A.C., Hall, N., Radford, A.D., Zuerner, R.L. 2015. Complete genome sequence of Leptospira interrogans serovar Bratislava, strain PigK151. Genome Announcements. 3(3):e00678-15. DOI: 10.1128/genomeA.00678-15.The etiology of digital dermatitis in ruminants: recent perspectives
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Alt, D.P., Nally, J.E. 2015. The etiology of digital dermatitis in ruminants: recent perspectives. Veterinary Medicine: Research and Reports. 2015(6):155-164.Biochemical and molecular characterization of Treponema phagedenis-like spirochetes isolated from a bovine digital dermatitis lesion
                                                        

- (Peer Reviewed Journal)Wilson-Welder, J.H., Elliott, M.K., Zuerner, R.L., Bayles, D.O., Alt, D.P., Stanton, T.B. 2013. Biochemical and molecular characterization of Treponema phagedenis-like spirochetes isolated from a bovine digital dermatitis lesion. BMC Microbiology. 13:280. Available: http://www.biomedcentral.com/content/pdf/1471-2180-13-280.pdf.Expansion of the in vitro assay for Leptospira potency testing to other Serovars:  Case study with Leptospira hardjo
                                                        

- (Other)Alt, D.P., Wilson-Welder, J.H. 2013. Expansion of the in vitro assay for Leptospira potency testing to other serovars:  Case study with Leptospira hardjo. Biologicals. 41(5):323-324.Single immunization with a suboptimal antigen dose encapsulated into polyanhydride microparticles promotes high titer and avid antibody responses

- (Peer Reviewed Journal)Huntimer, L., Wilson-Welder, J.H., Ross, K., Carrillo-Conde, B., Pruisner, L., Wang, C., Narasimhan, B., Wannemuehler, M.J., Ramer-Tait, A.E. 2013. Single immunization with a suboptimal antigen dose encapsulated into polyanhydride microparticles promotes high titer and avid antibody responses. Biomedical Materials Research. 101(1):91-98.Prospects in nasal vaccination against clinically relevant pathogens and select agents

- (Review Article)Hickey, A.J., Wilson-Welder, J.H., Metzger, D.W. 2011. Prospects in nasal vaccination against clinically relevant pathogens and select agents. Drugs of the Future. 36(8):589-599.


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