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                    U.S. DEPARTMENT OF AGRICULTURE
 Methods and Application of Food Composition Laboratory: Beltsville, MD
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ARS Home Northeast Area Beltsville, Maryland (BHNRC) Beltsville Human Nutrition Research Center Methods and Application of Food Composition Laboratory People & Locations







Pei  Chen
                        Methods and Application of Food Composition Laboratory

                        




                        
                        Research Chemist
                        Phone: (301) 504-8144
                         ext. 238
                        
                        Fax: (301) 504-8314(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsDevelopment of Analytical and Chemometric Methods for Identification and Authentication of Foods and Botanical Supplements
                                                    Cooperative Agreement
                                                                    (A)Accession Number: 436639Foodomics: New Tools for Food Composition
                                                    In-House Appropriated
                                                                    (D)Accession Number: 445346Farm to Table Factors: Impact of Production, Processing, and Preparation on Food Composition
                                                    In-House Appropriated
                                                                    (D)Accession Number: 445356**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Steroidal glycoalkaloids contribute to anthracnose resistance in solanum lycopersicum
                                                        

- (Peer Reviewed Journal)Fabian, M.L., Zhang, C., Sun, J., Price, N.P., Chen, P., Clarke, C.R., Jones, R.W., Stommel, J.R. 2023. Steroidal glycoalkaloids contribute to anthracnose resistance in solanum lycopersicum. Journal of Experimental Botany. 74(12):3700-3713. https://doi.org/10.1093/jxb/erad108.Chemical compositions of clove (Syzygium aromaticum (L.) Merr. & L.) extracts and their potentials in suppressing SARS-CoV-2 spike protein-ACE2 binding, inhibiting ACE2, and scavenging free radicals
                                                        

- (Peer Reviewed Journal)Li, Y., Liu, Z., Zeng, M., El Kadiri, A., Huang, J., Kim, A., He, X., Sun, J., Chen, P., Wang, T.T., Zhang, Y., Gao, B., Xie, Z., Yu, L. 2022. Chemical compositions of clove (Syzygium aromaticum (L.) Merr. & L.) extracts and their potentials in suppressing SARS-CoV-2 spike protein-ACE2 binding, inhibiting ACE2, and scavenging free radicals. Journal of Agricultural and Food Chemistry. 70(45):14403-14413. https://doi.org/10.1021/acs.jafc.2c06300.Effects of different light-emitting diode illumination on bioactive compounds in mustard “Ruby Streak” microgreens by Ultra-high Performance Liquid Chromatography High-Resolution Mass Spectrometry
                                                        

- (Peer Reviewed Journal)Liu, Z., Teng, Z., Pearlstein, D.J., Chen, P., Yu, L., Zhou, B., Luo, Y., Sun, J. 2022. Effects of different light-emitting diode illumination on bioactive compounds in mustard “Ruby Streak” microgreens by ultra-high performance liquid chromatography high-resolution mass spectrometry. ACS Food Science and Technology. 2(9):1483–1494. https://doi.org/10.1021/acsfoodscitech.2c00193.Identification of soluble free, soluble conjugated and insoluble bound phenolics in tomato seeds and their radical scavenging and antiproliferative activities
                                                        

- (Peer Reviewed Journal)Li, Y., Liu, Z., Tamia, G., He, X., Sun, J., Chen, P., Lee, S., Wang, T.T., Gao, B., Xie, Z., Yu, L. 2022. Identification of soluble free, soluble conjugated and insoluble bound phenolics in tomato seeds and their radical scavenging and antiproliferative activities. Journal of Agricultural and Food Chemistry. 70(29):9039-9047. https://pubs.acs.org/doi/10.1021/acs.jafc.2c03418.Mass Spectrometry Based Non-Targeted and Targeted Analytical Approaches in Fingerprinting and Metabolomics of Food and Agricultral Research
                                                        

- (Review Article)Zhihao, L., Mengliang, Z., Chen, P., Harnly, J.M., Sun, J. 2022. Mass spectrometry based non-targeted and targeted analytical approaches in fingerprinting and metabolomics of food and agricultral research. Journal of Agriculture and Food Chemistry. 70(36):11138–11153. https://doi.org/10.1021/acs.jafc.2c01878.Contrast study on secondary metabolite profile between pastas
made from three single varietal common bean (Phaseolus vulgaris
L.) and durum wheat (Triticum durum)
                                                        

- (Peer Reviewed Journal)Geng, P., Hooper, S., Sun, J., Chen, P., Cichy, K.A., Harnly, J.M. 2022. Contrast study on secondary metabolite profile between pastas made from three single varietal common bean (Phaseolus vulgaris L.) and durum wheat (Triticum durum). ACS Food Science and Technology. 2(5):895–904. https://doi.org/10.1021/acsfoodscitech.2c00050.Profiling of polyphenols and glucosinolates in kale and broccoli microgreens grown under chamber and windowsill conditions by ultrahigh-performance liquid chromatography high-resolution mass spectrometry
                                                        

- (Peer Reviewed Journal)Liu, Z., Shi, J., Wan, J., Pham, Q., Zhang, Z., Sun, J., Yu, L., Luo, Y., Wang, T.T.Y., Chen, P. 2021. Profiling of polyphenols and glucosinolates in kale and broccoli microgreens grown under chamber and windowsill conditions by ultrahigh-performance liquid chromatography high-resolution mass spectrometry. ACS Food Science and Technology. 2(1):101-113. https://doi.org/10.1021/acsfoodscitech.1c00355.Identification of marker compounds for predicting browning of fresh-cut lettuce using untargeted UHPLC-HRMS metabolomics
                                                        

- (Peer Reviewed Journal)Liu, Z., Sun, J., Teng, Z., Luo, Y., Yu, L., Simko, I., Chen, P. 2021. Identification of marker compounds for predicting browning of fresh-cut lettuce using untargeted UHPLC-HRMS metabolomics. Postharvest Biology and Technology. 180.Article 111626. https://doi.org/10.1016/j.postharvbio.2021.111626.Pre-harvest UV-B applications increases glucosinolate contents and enhances the postharvest quality of broccoli microgreen
                                                        

- (Peer Reviewed Journal)Lu, Y., Dongg, W., Yang, T., Luo, Y., Chen, P., Wang, Q. 2021. Pre-harvest UV-B applications increases glucosinolate contents and enhances the postharvest quality of broccoli microgreen. Molecules. 26:3247. https://doi.org/10.3390/molecules26113247.Classification of structural characteristics facilitate identifying steroidal saponins inAlliums using ultra-high performance liquid chromatography high-resolution massspectrometry
                                                        

- (Peer Reviewed Journal)Geng, P., Chen, P., Lin, L., Sun, J., Harrington, P., Harnly, J.M. 2021. Classifi cation of structural characteristics facilitate identifying steroidal saponins inAlliums using ultra-high performance liquid chromatography high-resolution massspectrometry . Journal of Food Composition and Analysis. 102:103994. https://doi.org/10.1016/j.jfca.2021.103994.Chemical composition of tomato seed flours, and their radical scavenging, anti-inflammatory and gut microbiota modulating properties
                                                        

- (Peer Reviewed Journal)Choe, U., Sun, J., Bailoni, E., Chen, P., Li, Y., Goa, B., Wang, T.T., Rao, J., Yu, L. 2021. Chemical composition of tomato seed flours, and their radical scavenging, anti-inflammatory and gut microbiota modulating properties. Molecules. 26(5):1478. https://doi.org/10.3390/molecules26051478.Study on human urinary metabolic profiles after consumption of kale and daikon radish using high-resolution mass spectrometry-based non-targeted and targeted metabolomic approach
                                                        

- (Peer Reviewed Journal)Sun, J., Charron, C.S., Zhihao, L., Novotny Dura, J., Harrington, P.B., Ross, S.A., Seifried, H.E., Chen, P. 2020. Study on human urinary metabolic profiles after consumption of kale and daikon radish using high-resolution mass spectrometry-based non-targeted and targeted metabolomic approach. Journal of Agricultural and Food Chemistry. 68:14307-14318. https://doi.org/10.1021/acs.jafc.0c05184.A systematic approach to determine the impact of elevated CO2 levels on the chemical composition of wheat (Triticum aestivum)
                                                        

- (Peer Reviewed Journal)Geng, P., Sun, J., Chen, P., Li, Y., Peng, B., Harnly, J.M. 2020. A systematic approach to determine the impact of elevated CO2 levels on the chemical composition of wheat (Triticum aestivum). Journal of Cereal Science. 95:753. https://doi.org/10.1016/j.jcs.2020.103020.Quantification of cranberry proanthocyanidins by normal phase high performance liquid chromatography using relative response factors
                                                        

- (Peer Reviewed Journal)Sinatara, M., Wang, Y., Li, L., Liu, H., Cunningham, D.G., Prior, R.L., Chen, P., Chang, T., Wu, X. 2020. Quantification of cranberry proanthocyanidins by normal phase high performance liquid chromatography using relative response factors. Phytochemical Analysis. 31:874-883. https://doi.org/10.1002/pca.2952.Characterization of Maca (Lepidium meyenii/Lepidium peruvianum)
Using a Mass Spectral Fingerprinting, Metabolomic Analysis,
and Genetic Sequencing Approach
                                                        

- (Peer Reviewed Journal)Geng, P., Sun, J., Brand, E., Frame, J., Meissner, H., Stewart, J., Clark, S., Miller, J., Harnly, J.M., Chen, P., Gafner, S. 2020. Characterization of Maca (Lepidium meyenii/Lepidium peruvianum) using a mass spectral fingerprinting, metabolomic analysis, and genetic sequencing approach. Planta Medica. 169:453–468. https://doi.org/10.1055/a-1161-0372.Analysis of Cranberry Proanthocyanidins  Using UPLC - Ion Mobility - High Resolution Mass Spectrometry
                                                        

- (Peer Reviewed Journal)Wang, Y., Harrington, P.B., Chang, T., Wu, X., Chen, P. 2020. Analysis of cranberry proanthocyanidins using UPLC - ion mobility - high resolution mass spectrometry. Analytical and Bioanalytical Chemistry. 412:3653-3662. https://doi.org/10.1007/s00216-020-02601-z.Effect of nighttime UV-C irradiation of strawberry plants on phenolic content of fruit: targeted and non-targeted metabolomic analysis
                                                        

- (Peer Reviewed Journal)Sun, J., Janisiewicz, W.J., Takeda, F., Evans, B.E., Jurick Ii, W.M., Zhang, M., Yu, L., Chen, P. 2020. Effect of nighttime UV-C irradiation of strawberry plants on phenolic content of fruit: targeted and non-targeted metabolomic analysis. Journal of Berry Research. 10(3):365-380. https://doi.org/10.3233/JBR-190482.Chemical composition of cold-pressed blackberry seed flour extract and its potential health-beneficial properties
                                                        

- (Peer Reviewed Journal)Choe, U., Li, Y., Gao, B., Yu, L., Wang, T.T., Sun, J., Chen, P., Yu, L. 2020. Chemical composition of cold-pressed blackberry seed flour extract and its potential health-beneficial properties. Food Science and Nutrition. 8(2):1215-1225. https://doi.org/10.1002/fsn3.1410.Chemical profile and in vitro gut microbiota modulatory, anti-inflammatory and free radical scavenging Properties of chrysanthemum morifolium cv. Fubaiju
                                                        

- (Peer Reviewed Journal)Li, Y., Hao, Y., Gao, B., Geng, P., Huang, H., Yu, L., Choe, U., Liu, J., Sun, J., Chen, P., Wang, T.T.Y., Yu, L. 2019. Chemical profile and in vitro gut microbiota modulatory, anti-inflammatory and free radical scavenging properties of chrysanthemum morifolium cv. Fubaiju. Journal of Functional Foods. 58:114-122. https://doi.org/10.1016/j.jff.2019.04.053.Determination of variance of secondary metabolites in lettuces grown under different light sources by flow injection mass spectrometric (FIMS) fingerprinting and ANOVA-PCA
                                                        

- (Peer Reviewed Journal)Sun, J., Zhang, M., Luo, Y., Kubdelia, N., Harnly, J.M., Chen, P. 2018. Determination of variance of secondary metabolites in lettuces grown under different light sources by flow injection mass spectrometric (FIMS) fingerprinting and ANOVA-PCA. Journal of Analysis and Testing. 2(4):312-321. https://doi.org/10.1007/s41664-018-0072-6.Non-targeted metabolomic study of different American cranberry cultivars using UPLC-IM-HRMS

- (Peer Reviewed Journal)Wang, Y., Vorsa, N., Harrington, P.B., Chen, P. 2018. Non-targeted metabolomic study of different American cranberry cultivars using UPLC-IM-HRMS. Journal of Agricultural and Food Chemistry. 66:12206-12216.Microgreens of Brassicaceae: Genetic diversity of phytochemical concentrations and antioxidant capacities

- (Peer Reviewed Journal)Xiao, Z., Rausch, S.R., Luo, Y., Sun, J., Yu, L., Wang, Q., Chen, P., Yu, L., Stommel, J.R. 2018. Microgreens of Brassicaceae: Genetic diversity of phytochemical concentrations and antioxidant capacities. LWT - Food Science and Technology. 101:731-737.Chemical compositions of cold-pressed broccoli, carrot and cucumber seed flours, and their in vitro gut microbiota modulatory, anti-inflammatory and free radical scavenging properties
                                                        

- (Peer Reviewed Journal)Choe, U., Li, Y., Gao, B., Yu, L., Wang, T.T., Sun, J., Chen, P., Liu, J., Yu, L. 2018. Chemical compositions of cold-pressed broccoli, carrot and cucumber seed flours, and their in vitro gut microbiota modulatory, anti-inflammatory and free radical scavenging properties. Journal of Agricultural and Food Chemistry. 66(35):9309-0317. https://doi.org/10.1021/acs.jafc.8b03343.Comparison of ion mobility fuzzy chromatography mass spectrometric (iFCMS) fingerprinting and FCMS fingerprinting for differentiation of American cranberry cultivars

- (Peer Reviewed Journal)Wang, Y., Chen, P. 2018. Comparison of ion mobility fuzzy chromatography mass spectrometric (iFCMS) fingerprinting and FCMS fingerprinting for differentiation of American cranberry cultivars. Journal of Analysis and Testing. 2(4):7388-7397.Effect of preharvest CaCl2 spray and postharvest UV-B radiation on storage quality of broccoli microgreens, a richer source of glucosinolates
                                                        

- (Peer Reviewed Journal)Lu, Y., Dong, W., Yang, T., Luo, Y., Wang, Q., Chen, P. 2017. Effect of preharvest CaCl2 spray and postharvest UV-B radiation on storage quality of broccoli microgreens, a richer source of glucosinolates. Journal of Food Composition and Analysis. 67(1):55-62. https://doi.org/10.1016/j.jfca.2017.12.035.Challenges of developing a valid Dietary Glucosinolate database
                                                        

- (Peer Reviewed Journal)Wu, X., Sun, J., Haytowitz, D.B., Harnly, J.M., Chen, P., Pehrsson, P.R. 2017. Challenges of developing a valid Dietary Glucosinolate database. Journal of Food Composition and Analysis. https://doi.org/10.1016/j.jfca.2017.07.014.Develop a Comprehensive Flavonoid Analysis Computational Tool for UHPLC-DAD- HRAM-MSn Data

- (Peer Reviewed Journal)Zhang, M., Sun, J., Chen, P. 2017. Develop a Comprehensive Flavonoid Analysis Computational Tool for UHPLC-DAD- HRAM-MSn Data. Analytical Chemist. 89 (4):7388-7397.Botanical supplements: detecting the transition from ingredients to supplements
                                                        

- (Peer Reviewed Journal)Harnly, J.M., Lu, Y., Sun, J., Chen, P. 2017. Botanical supplements: detecting the transition from ingredients to supplements. Journal of Food Composition and Analysis. 64:85-92. https://doi.org/10.1016/j.jfca.2017.06.010.Dual effectiveness of ascorbic acid and ethanol combined treatment to inhibit browning and inactivate pathogens on fresh-cut apples

- (Peer Reviewed Journal)Yan, S., Liu, H., Yang, T., Luo, Y., Chen, P. 2017. Dual effectiveness of ascorbic acid and ethanol combined treatment to inhibit browning and inactivate pathogens on fresh-cut apples. LWT - Food Science and Technology. 80:311-320.Composition of phenolic compounds in wild apple with multiple resistance mechanisms against postharvest blue mold decay

- (Peer Reviewed Journal)Sun, J., Janisiewicz, W.J., Evans, B.E., Jurick II, W.M., Chen, P. 2017. Composition of phenolic compounds in wild apple with multiple resistance mechanisms against postharvest blue mold decay. Postharvest Biology and Technology. 127:68-75.Feruloyl dopamine-O-hexosides are efficient marker compounds for differentiation between Black Cohosh (Actaea racemosa) and related Actaea species – an UHPLC-HRAM-MS Chemometrics Study
                                                        

- (Peer Reviewed Journal)Geng, P., Harnly, J.M., Sun, J., Zhang, M., Chen, P. 2017. Feruloyl dopamine-O-hexosides are efficient marker compounds for differentiation between Black Cohosh (Actaea racemosa) and related Actaea species – an UHPLC-HRAM-MS Chemometrics Study. Analytical and Bioanalytical Chemistry. 127:68-75. https://doi.org/10.1016/j.postharvbio.2017.01.006.Comprehensive characterization of C-glycosyl flavones in wheat (Triticum aestivum L.) germ using UPLC-PDA-ESI/HRMSn and mass defect filtering

- (Peer Reviewed Journal)Geng, P., Sun, J., Zhang, M., Li, X., Harnly, J.M., Chen, P. 2016. Comprehensive characterization of C-glycosyl flavones in wheat (Triticum aestivum L.) germ using UPLC-PDA-ESI/HRMSn and mass defect filtering. Journal of Mass Spectrometry. 64:4407-4415.GLS-Finder: An Automated Data-Mining System for Fast Profiling Glucosinolates and its Application in Brassica Vegetables

- (Peer Reviewed Journal)Sun, J., Zhang, M., Chen, P. 2016. GLS-Finder: An Automated Data-Mining System for Fast Profiling Glucosinolates and its Application in Brassica Vegetables. Analytical Chemistry. 4407:4415.Differentiation of Bread Made with Whole Grain and Refined Wheat (T. aestivum) Flour Using LC/MS-based chromatographic Fingerprinting and Chemometric Approaches

- (Peer Reviewed Journal)Geng, P., Harnly, J.M., Chen, P. 2016. Differentiation of Bread Made with Whole Grain and Refined Wheat (T. aestivum) Flour Using LC/MS-based chromatographic Fingerprinting and Chemometric Approaches. Journal of Food Composition and Analysis. 47:92-100.Differentiation of the two major species of Echinacea (E. augustifolia and E. purpurea) using a flow injection mass spectrometric (FIMS) fingerprinting method and chemometric analysis

- (Peer Reviewed Journal)Lu, Y., Chen, P. 2015. Differentiation of the two major species of Echinacea (E. augustifolia and E. purpurea) using a flow injection mass spectrometric (FIMS) fingerprinting method and chemometric analysis. Analytical Methods. 4:246-251.Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis

- (Peer Reviewed Journal)Angelino, D., Dosz,.B., Sun, J., Hoeflinger, J.L., Van Tassell, M.L., Chen, P., Harnly, J.M., Miller, M.J., Jeffery, E.H. 2015. Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis. Frontiers in Plant Science. doi: 10.3389/fpls.2015.00831.FlavonQ: An Automated Data Processing Tool for Profiling Flavone/flavonol Glycosides Using Ultra High-performance Liquid Chromatography Diode Array Detection and High-Resolution Accurate-Mass Mass Spectrometry (UHPLC HRAM-MS)

- (Peer Reviewed Journal)Zhang, M., Sun, J., Chen, P. 2015. FlavonQ: An Automated Data Processing Tool for Profiling Flavone/flavonol Glycosides Using Ultra High-performance Liquid Chromatography Diode Array Detection and High-Resolution Accurate-Mass Mass Spectrometry (UHPLC HRAM-MS). Analytical Chemist. 87:9974-9981.Comparison of Flow Injection MS, NMR, and DNA Sequencing: Methods for Identification and Authentication of Black Cohosh (Actaea racemosa)

- (Peer Reviewed Journal)Harnly, J.M., Chen, P., Sun, J., Huang, H., Colson, K., Yu, J., Mccoy, J.H., Harbaugh Reynaud, D.T., Harrington, P.B., Fletcher, E. 2015. Comparison of Flow Injection MS, NMR, and DNA Sequencing: Methods for Identification and Authentication of Black Cohosh (Actaea racemosa). Planta Medica. 82:250-262.Differentiation of whole grain and refined wheat (T. aestivum) flour using a fuzzy mass spectrometric fingerprinting and chemometric approaches

- (Peer Reviewed Journal)Geng, P., Harnly, J.M., Chen, P., Luthria, D.L., Zhang, M. 2015. Differentiation of whole grain and refined wheat (T. aestivum) flour using a fuzzy mass spectrometric fingerprinting and chemometric approaches. Journal of Agricultural and Food Chemistry. 407:7875-7888.AOAC SMPR 2014.007: Authentication of selected Vaccinium species (Anthocyanins) in dietary ingredients and dietary supplements
                                                        

- (Peer Reviewed Journal)Krueger, D., Arora, S., Bzhelyansky, A., Chen, P., Chlenov, A., Collison, M., Durst, R., Es-Safi, N., Giancaspro, G., Hall, G., Hammerstone, J., Ingle, P., Jennens-Clough, M., Ji, D., Ji, J., Kennedy, D., Lawson, T., Lee, J., Lock, S., Mudge, E., Neal-Kababick, J., Phillips, M., Phillips, T., Rejaei, A., Rettinger, M., Rimmer, C., R.-Haralambides, A., Royce, S., Schaneberg, B., Solyom, A., Stern, N., Sullivan, D., Szpylka, J., Wise, M.L., Yan, X., Yoo, S., Yu, K., Zhang, Y., Coates, S. 2015. AOAC SMPR 2014.007: Authentication of selected Vaccinium species (Anthocyanins) in dietary ingredients and dietary supplements. Journal of AOAC International. 98(4):1052-1054. https://doi.org/10.5740/jaoac.int.SMPR2014.007.Differentiation of whole grain from refined wheat (T. aestivum) flour using lipid profile of wheat bran, germ, and endosperm with UHPLC-HRAM mass spectrometry”

- (Peer Reviewed Journal)Geng, P., Harnly, J.M., Chen, P. 2015. Differentiation of whole grain from refined wheat (T. aestivum) flour using lipid profile of wheat bran, germ, and endosperm with UHPLC-HRAM mass spectrometry”. Journal of Agricultural and Food Chemistry. 63:6189-6211.Fingerprinting profile of polysaccharides from Lycium barbarum using multiplex approaches and chemometrics

- (Peer Reviewed Journal)Lu, W., Xu, J., Zhu, R., Zhu, Y., Zhao, Y., Chen, P., Pan, C., Yao, W., Gao, X. 2015. Fingerprinting profile of polysaccharides from Lycium barbarum using multiplex approaches and chemometrics. International Journal of Biological Macromolecules. 3:78:230-237.Discrimination of Aurantii Fructus Immaturus and Fructus Poniciri Trifoliatae Immaturus by Flow Injection UV Spectroscopy (FIUV) and  1H NMR using Partial Least-squares Discriminant Analysis (PLS-DA)

- (Peer Reviewed Journal)Zahang, M., Zhang, Y., Harrington, P.B., Chen, P. 2015. Discrimination of Aurantii Fructus Immaturus and Fructus Poniciri Trifoliatae Immaturus by Flow Injection UV Spectroscopy (FIUV) and  1H NMR using Partial Least-squares Discriminant Analysis (PLS-DA). Analytical Letters. 49:711-722.Metabolomic assessment reveals a stimulatory effect of calcium treatment on glucosinolates contents in broccoli microgreen
                                                        

- (Peer Reviewed Journal)Sun, J., Kou, L., Geng, P., Huang, H., Yang, T., Luo, Y., Chen, P. 2015. Metabolomic assessment reveals a stimulatory effect of calcium treatment on glucosinolates contents in broccoli microgreen. Journal of Agricultural and Food Chemistry. 8:63(6):1863-1868.Characterization of phenolic amides from cortex lycii by ultra high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry

- (Peer Reviewed Journal)Zhang, J., Guan, S., Sun, J., Liu, T., Chen, P., Feng, R., Chen, X., Hou, J., Yang, W., Wu, W., Yang, M., Guo, D. 2014. Characterization of phenolic amides from cortex lycii by ultra high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 407:581-95.High fat diet leads to changes in metabolite patterns in pig plasma, fecal, and urine samples detected by a ultra-high performance liquid chromatography tandem with high resolution mass spectrometry metabolomic study

- (Peer Reviewed Journal)Sun, J., Monagas, M., Jang, S.,  Molokin, A., Harnly, J.M., Urban, J.F., Aguilar, G., Chen, P. 2014. High fat diet leads to changes in metabolite patterns in pig plasma, fecal, and urine samples detected by a ultra-high performance liquid chromatography tandem with high resolution mass spectrometry metabolomic study. Food Chemistry. 15:173:171-178.Profiling of Glucosinolates and Flavonoids in Rorippa indica (Linn.) Hiern. (Cruciferae) by UHPLC-PDA-ESI/HRMSn.

- (Peer Reviewed Journal)Lin, L., Sun, J., Chen, P., Zhang, R., Fan, X., Li, L., Harnly, J.M. 2014. UHPLC-DAD-ESI/HRMSn method to identify the glucosinolates and flavonoids of Rorippa montana (Wall) Small.. Journal of Agricultural and Food Chemistry. 62:6118-6129.Natural products with health benefits from marine biological resources

- (Peer Reviewed Journal)Zhao, Y., Chen, P. 2014. Natural products with health benefits from marine biological resources. Current Organic Chemistry. 10.2174/138527281807140515132853.Recent advances in ultra-high performance liquid chromatography for the analysis of traditional chinese medicine

- (Peer Reviewed Journal)Huang, J., Liu, M., Chen, P. 2014. Recent advances in ultra-high performance liquid chromatography for the analysis of traditional chinese medicine. Analytical Letters. DOI: 10.1080/00032719.2014.888727.Differentiation of the four major types (C. Burmannii, C. Verum, C. cassia, And C. Loureiroi)  of cinnamons using a flow-injection mass spectrometric (FIMS) fingerprinting method

- (Peer Reviewed Journal)Chen, P., Sun, J., Ford, P. 2014. Differentiation of the four major types (C. Burmannii, C. Verum, C. cassia, And C. Loureiroi)  of cinnamons using a flow-injection mass spectrometric (FIMS) fingerprinting method. Analytical and Bioanalytical Chemistry. 10.1021/jf405580c.Anthocyanidins and polyphenols in five brassica species microgreens: analysis by UHPLC-PDA-ESI/HRMS/MSn

- (Peer Reviewed Journal)Sun, J., Xiao, Z., Lin, L., Lester, G.E., Wang, Q., Harnly, J.M., Chen, P. 2013. Anthocyanidins and polyphenols in five brassica species microgreens: analysis by UHPLC-PDA-ESI/HRMS/MSn. Journal of Agricultural and Food Chemistry. 61:10960-10970.Single laboratory validation of the determination of yohimbine in yohimbe bark and related dietary supplements using UHPLC/UV/MS

- (Peer Reviewed Journal)Chen, P., Bryden, N.A. 2015. Single laboratory validation of the determination of yohimbine in yohimbe bark and related dietary supplements using UHPLC/UV/MS. Journal of Association of Official Analytical Chemists International. 98:896-901.Differentiation of leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum (Thunb.) Makino using flow-injection mass spectrometric(FIMS) fingerprinting method combined with chemometric approaches

- (Peer Reviewed Journal)Zhao, Y., Niu, Y., Xie, Z., Shi, H., Chen, P., Yu, L. 2013. Differentiation of leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum (Thunb.) Makino using flow-injection mass spectrometric(FIMS) fingerprinting method combined with chemometric approaches. Analytica Chimica Acta. 5:1288-1297.Detection of adulterated Ginkgo biloba supplements using chromatographic and spectral fingerprints

- (Peer Reviewed Journal)Harnly, J.M., Luthria, D.L., Chen, P. 2012. Detection of adulterated Ginkgo biloba supplements using chromatographic and spectral fingerprints. Journal of Association of Official Analytical Chemists International. 95:6.Differentiation of leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum (Thunb.) Makino using flow-injection mass spectrometric(FIMS) fingerprinting method combined with chemometric approaches

- (Peer Reviewed Journal)Differentiating organic and conventional sage by chromatographic and mass spectrometry flow-injection fingerprints

- (Peer Reviewed Journal)Gao, B., Lu, Y., Chen, P., Liangli, Y. 2013. Differentiating Organic and Conventional Sage by Chromatographic and Mass Spectrometry Flow-Injection Fingerprints. Journal of Agricultural and Food Chemistry. 61:2957-2963.Authentication of organically and conventionally grown basils by gas chromatograpy/mass spectrometry chemical profiles

- (Peer Reviewed Journal)Wang, Z., Chen, P., Yu, L., Harrington, P.B. 2013. Authentication of organically and conventionally grown basils by gas chromatograpy/mass spectrometry chemical profiles. Analytical Chemistry. 85:2945-2953.Profiling polyphenols of two diploid strawberry (Fragaria vesca) inbred lines using UHPLC-HRMSn

- (Peer Reviewed Journal)Sun, J., Liu, X., Yang, T., Solvin, J., Chen, P. 2013. Profiling polyphenols of two diploid strawberry (Fragaria vesca) inbred lines using UHPLC-HRMSn. Analytical Biochemistry. 5:2945-53.Encapsulation of indole-3-carbinol and 3'3'-diindolylmethane in zein/carboxymethyl chitosan nanoparticles with controlled release property and improved stability

- (Peer Reviewed Journal)Lou, Y., Wang, T.T., Teng, Z., Chen, P., Sun, J., Wang, Q. 2013. Encapsulation of indole-3-carbinol and 3'3'-diindolylmethane in zein/carboxymethyl chitosan nanoparticles with controlled release property and improved stability. Food Chemistry. 139(1-4):224-30.Chromatographic and mass spectrometric fingerprinting analyses of 
angelica sinensis (Oliv.) diels dietary supplements

- (Peer Reviewed Journal)Zhao, Y., Sun, J., Yu, L., Chen, P. 2013. Chromatographic and mass spectrometric fingerprinting analyses of  angelica sinensis (Oliv.) diels dietary supplements. Analytical and Bioanalytical Chemistry. doi: 10.1007/s00216-012-6668-1.Differentiating organic from conventional peppermints using chromatographic and flow-injection mass spectrometric (FIMS) fingerprints

- (Peer Reviewed Journal)Gao, B., Qin, F., Chen, P., Shi, H., Liangli, L. 2012. Differentiating organic from conventional peppermints using chromatographic and flow-injection mass spectrometric (FIMS) fingerprints. Journal of Agricultural and Food Chemistry. 60:11987-11994.UHPLC/HRMS analysis of African mango (Irvingia gabonensis) seeds, seed extracts, and African mango based dietary supplements

- (Peer Reviewed Journal)Sun, J., Chen, P. 2012. UHPLC/HRMS analysis of African mango (Irvingia gabonensis) seeds, seed extracts, and African mango based dietary supplements. Journal of Agricultural and Food Chemistry. 60:8703-8709.Classification of cultivation locations of Panax quinquefolius L samples using high performance liquid chromatography-electrospray ionization mass spectrometry and chemometric analysis

- (Peer Reviewed Journal)Sun,, X., Chen, P., Cook, S., Jackson, G., Harnly, J.M., Harrington, P. 2013. Classification of cultivation locations of Panax quinquefolius L samples using high performance liquid chromatography-electrospray ionization mass spectrometry and chemometric analysis. Analytical Chemistry. 84:3628-3634.Classification of cultivation locations of panax quinquefolius L samples using high performance liquid chromatography-electrospray ionization mass spectrometry and chemometric analysis

- (Peer Reviewed Journal)Sun, X., Chen, P., Cook, S., Jackson, G., Harnly, J.M., Harrington, P. 2012. Classification of cultivation locations of panax quinquefolius L samples using high performance liquid chromatography-electrospray ionization mass spectrometry and chemometric analysis. Analytical Chemist. 84:3628-3634.Recent applications for HPLC-MS analysis of anthocyanins in Food materials

- (Peer Reviewed Journal)Sun, J., Long-Ze, L., Chen, P. 2013. Recent applications for HPLC-MS analysis of anthocyanins in Food materials. Current Analytical Chemistry. 9:397-416.Study of the mass spectrometric behaviors of anthocyanins in negative ionization mode and its applications for characterization of anthocyanins and non-anthocyanin polyphenols

- (Peer Reviewed Journal)Sun, J., Lin, L., Chen, P. 2012. Study of the mass spectroscopic behaviors of anthocyanins in negative ionization mode and its applications for fast differentiation of anthocyanins and non-anthocyanin polyphenols in natural products. Rapid Communications in Mass Spectrometry. 26:-1123-1132.UHPLC-PDA-ESI/HRMS/MSn analysis of anthocyanins, flavonol glycosides, and hydroxycinnamic acid derivatives in red mustard green (Brassica juncea (L) Coss variety)

- (Peer Reviewed Journal)Lin, L., Sun, J., Chen, P., Harnly, J.M. 2011. UHPLC-PDA-ESI/HRMS/MSn analysis of anthocyanins, flavonol glycosides, and hydroxycinnamic acid derivatives in red mustard green (Brassica juncea (L) Coss variety). Journal of Agricultural and Food Chemistry. 60:544-553.Chemical composition, and anti-proliferative and anti-inflammatory effects of the leaf and wholeplant samples of diploid and tetraploid gynostemma pentaphyllum

- (Peer Reviewed Journal)Xie, Z., Huang, H., Zhao, Y., Shi,, H., Wang, S., Wang, T.T., Chen, P., Yu, L. 2011. Chemical composition, and anti-proliferative and anti-inflammatory effects of the leaf and wholeplant samples of diploid and tetraploid gynostemma pentaphyllum. Food Chemistry. 132:125-133.High-performance Liquid Chromatography Mass Spectrometry Analysis of Pantothenic acid (Vitamin B5) in Multivitamin Dietary Supplements

- (Abstract Only)A flow-injection mass spectrometry fingerprinting method
for authentication and quality assessment of Scutellaria
lateriflora-based dietary supplements

- (Peer Reviewed Journal)Sun, J., Chen, P. 2011. A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements. Analytical and Bioanalytical Chemistry. 401:1577-1584.A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements

- (Peer Reviewed Journal)Sun, J., Long-Ze, L., Chen, P. 2011. A flow-injection mass spectrometry fingerprinting method for authentication and quality assessment of Scutellaria lateriflora-based dietary supplements. Analytical and Bioanalytical Chemistry. 401:1577-1584.Profiling the indole alkaloids in yohimbe bark with ultra-performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry

- (Peer Reviewed Journal)Sun, J., Chen, P. 2011. Profiling the indole alkaloids in yohimbe bark with ultra-performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry. Journal of Rapid Communications in Mass Spectroscopy. 25:2591-2602.LC-PDA-EIS/MSn identification of new anthocyanins in purple radish (Raphanus sativus L. variety)

- (Peer Reviewed Journal)Lin, L., Jianghao, S., Chen, P., Harnly, J.M. 2011. LC-PDA-EIS/MSn identification of new anthocyanins in purple radish (Raphanus sativus L. variety). Journal of Agricultural  food Chemistry . 59:6616-6627.Differentiation of Panax quinquefolius grown in United States and China using LC/MS-based chromatographic fingerprinting and metabolomic approaches

- (Peer Reviewed Journal)Sun, J., Chen, P. 2011. Differentiation of Panax quinquefolius grown in United States and China using LC/MS-based chromatographic fingerprinting and metabolomic approaches. Analytical Biochemistry. 58(8):4545-4553.Identification, quantitation, and comprehensive assessment of green, white, and pu-erh teas using UPLC/UV/MS

- (Peer Reviewed Journal)Zhao, Y., Chen, P., Lin, L., Harnly, J.M. 2011. Identification, quantitation, and comprehensive assessment of green, white, and pu-erh teas using UPLC/UV/MS. Food Chemistry. 126:1269-1277.Discrimination among Panax species using spectral fingerprinting

- (Peer Reviewed Journal)Chen, P., Luthria, D.L., Harrington, P.B., Harnly, J.M. 2011. Discrimination among Panax species using spectral fingerprinting. Journal of the Association of Official Analytical Chemists. 94:1411-1421.Chromatographic fingerprint analysis and rutin and quercetin compositions in the leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum

- (Peer Reviewed Journal)Xie, Z., Zhao, Y., Chen, P., Yu, L. 2010. Chromatographic fingerprint analysis and rutin and quercetin compositions in the leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum. Journal of Agricultural and Food Chemistry. 7:3042-3049.A non-targeted approach to chemical discrimination between green tea extract-based dietary supplements and green tea leaves by LC/MS

- (Peer Reviewed Journal)Sun, J., Chen, P., Lin, L., Harnly, J.M. 2011. A non-targeted approach to chemical discrimination between green tea extract-based dietary supplements and green tea leaves by LC/MS. Journal of the Association of Official Analytical Chemists. 94:487-497.Rapid Mass Spectroscopic Fingerprinting Method and Principal Component Analysis for Differentiation between American Ginseng, Chinese Ginseng, and Notoginseng

- (Peer Reviewed Journal)Chen, P., Harnly, J.M. 2011. Rapid Mass Spectroscopic Fingerprinting Method and Principal Component Analysis for Differentiation between American Ginseng, Chinese Ginseng, and Notoginseng. Journal of the Association of Official Analytical Chemists. 94:90-99.A LC/UV/Vis method for determination of cyanocobalamin in multivitamin dietary supplements with on-line sample clean-up

- (Peer Reviewed Journal)Chen, P., Wolf, W.R., Castanheira, I., Sanches-Silva, A. 2010. A LC/UV/Vis method for determination of cyanocobalamin in multivitamin dietary supplements with on-line sample clean-up. Analytical Methods. 2:1171-1175.Flow injection mass spectral fingerprints demonstrate chemical differences in rio red grapefruit with respect to year, harvest time, and conventional versus organic farming

- (Peer Reviewed Journal)Chen, P., Harnly, J.M., Lester, G.E. 2010. Flow injection mass spectral fingerprints demonstrate chemical differences in Rio Red grapefruit with respect to year, harvest time, and conventional versus organic farming. Journal of Agriculture and Food Chemistry. 58(8):4545-4553.Mass spectroscopic fingerprinting method for to differentiation between Scutellaria lateriflora and the Germander (Teucrium canadens and T. chamaedrys species

- (Peer Reviewed Journal)Chen, P., Lin, L., Harnly, J.M. 2010. Mass spectroscopic fingerprinting method for differentiation between Scutellaria lateriflora and the Germander (Teucrium canadense and T. chamaedrys) species. Journal of AOAC International. 93(4):1148-1154.Certificate of Analysis, Standard Reference Material® 1849, Infant/Adult Nutritional Formula

- (Other)Wolf, W.R., Byrdwell, W.C., Chen, P., Goldschmidt, R.J., Atkinson, R.L. 2009. Certificate of Analysis, Standard Reference Material® 1849, Infant/Adult Nutritional Formula. Available NIST Website: https://www-s.nist.gov/srmors/view_detail.cfm?srm=1849.Single Lab Validation of a LC/UV/FLD/MS Method for Simultaneous Determination of Water-soluble Vitamins in Multi-Vitamin Dietary Supplements

- (Peer Reviewed Journal)Chen, P., Atkinson, R.L., Wolf, W.R. 2009. Single lab validation of a LC/UV/FLD/MS method for simultaneous determination of water-soluble vitamins in multi-vitamin dietary supplements. Journal of the Association of Official Analytical Chemists. 92(2):680-688.Chromatographic fingerprint analysis of Pycnogenol® dietary supplements

- (Peer Reviewed Journal)Chen, P., Song, F., Lin, L. 2009. Chromatographic fingerprint analysis of Pycnogenol® dietary supplements. Journal of AOAC International. 92(2):624-632.Chromatographic profiles of Ginkgo biloba leaves and selected products

- (Peer Reviewed Journal)Lin, L., Chen, P., Ozcan, M., Harnly, J.M. 2008. Chromatographic profiles of Ginkgo biloba leaves and selected products. Journal of Agricultural and Food Chemistry. http://dx.doi.org/10.1021/jf800488x.Factors Affecting Resveratrol Content in Strawberries

- (Abstract Only)Wang, S.Y., Chen, C., Wang, C.Y., Chen, P. 2008. Factors Affecting Resveratrol Content in Strawberries. HortScience. 43(4):1230.2008Fingerprint of Herb Product by Matrix-assisted Laser Desorption Ionization Mass Spectrometry

- (Abstract Only)Song, F., Chen, P. 2008. Fingerprint of Herb Product by Matrix-assisted Laser Desorption Ionization Mass Spectrometry. 2008 BARC Poster Day, April 23, 2008, Beltsville, MD.Simultaneous Determination of Water Soluble Vitamins in Dietary Supplements and Fortified Foods by LC-MS

- (Abstract Only)Wolf, W.R., Goldschmidt, R.J., Chen, P. 2008. Simultaneous Determination of Water Soluble Vitamins in Dietary Supplements and Fortified Foods by LC-MS.Midwest Section of AOAC International, 2008 Annual Meeting, June 9-11 2008, Bozeman, MT.Elucidation of the mechanism of enzymatic browning inhibition by sodium chlorite

- (Peer Reviewed Journal)He, Q., Luo, Y., Chen, P. 2008. Elucidation of the mechanism of enzymatic browning inhibition by sodium chlorite. Journal of Food Chemistry. 110(4):847-851.Spectral Fingerprints for Authentication and Identification of Variation in Foods and Botanical Materials

- (Abstract Only)Harnly, J.M., Luthria, D.L., Chen, P., Lin, L. 2008. Spectral Fingerprints for Authentication and Identification of Variation in Foods and Botanical Materials. Experimental Biololgy Meeting, April 5-9, 2008, San Diego, CA.Chromatographic Profiles of Ginkgo biloba Leaves and Selected Products

- (Abstract Only)Lin, L., Chen, P., Ozcan, M., Harnly, J.M. 2008. Chromatographic Profiles of Ginkgo biloba Leaves and Selected Products. Experimental Biololgy Meeting, April 5-9, 2008, San Diego, CA.Resveratrol Content in Strawberry Fruit is Affected by Preharvest Conditions

- (Peer Reviewed Journal)Wang, S.Y., Chen, C., Wang, C.Y., Chen, P. 2007. Resveratrol Content in Strawberry Fruit is Affected by Preharvest Conditions. Journal of Agriculture and Food Chemistry. 55:8269-8274.Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by Liquid Chromatography Isotope Dilution Mass Spectrometry

- (Peer Reviewed Journal)Chen, P., Ozcan, M., Wolf, W.R. 2007. Simultaneous determination of selected B vitamins in the NIST SRM 3280 multivitamin/multielement tablets by liquid chromatography isotope dilution mass spectrometry. Analytical and Bioanalytical Chemistry. Available: doi:10.1007/s00216-007-1430-9.Single Laboratory Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements (AOAC Annual Meeting, Minneapolis, MN, Sept, 2006)

- (Abstract Only)Chen, P., Wolf, W.R. 2007. Single Laboratory Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements. AOAC Annual Meeting, September 15, 2006, Minneapolis, Minnesota.Chromatographic fingerprints analysis for evaluation of Ginkgo Biloba products

- (Peer Reviewed Journal)Chen, P., Ozcan, M., Harnly, J.M. 2007. Chromatographic Fingerprints Analysis for Evaluation of Ginkgo Biloba Products. Analytical and Bioanalytical Chemistry. Available on-line doi: 10.1007/s00216-007-1386-9.Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by HPLC Isotope Dilution Mass Spectrometry

- (Abstract Only)Chen, P., Ozcan, M., Wolf, W.R. 2007. Simultaneous Determination of Selected B Vitamins in the NIST SRM 3280 Multivitamin/Multielement Tablets by HPLC Isotope Dilution Mass Spectrometry. BARC Poster Day, May, 2007, Beltsville, Maryland.Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements  (Experimental Biology, April, 2007, Washington, D.C.)

- (Abstract Only)Wolf, W.R., Chen, P. 2007. Validation of a LC/UV/MS Method for Determination of Multiple Water Soluble Vitamins in Dietary Supplements. Experimental Biology, April 25, 2007, Washington, D.C.Determination of Selected B-complex Vitamins in the NIST Multivitamin Reference Standard Material by Stable Isotope Dilution Mass Spectrometry  (Experimental Biology, April, 2007, Washington, D.C.)

- (Abstract Only)Chen, P., Ozcan, M., Wolf, W.R. 2007. Determination of Selected B-complex Vitamins in the NIST Multivitamin Reference Standard Material by Stable Isotope Dilution Mass Spectrometry. Experimental Biology, April 25, 2007, Washington, D.C.Determination of Ginkgolides and Flavonols in Ginkgo Biloba Products and NIST Ginkgo Reference Standard by LC/UV/MS  (Experimental Biology, April, 2007, Washington, D.C.)

- (Abstract Only)Ozcan, M., Chen, P. 2007. Determination of Ginkgolides and Flavonols in Ginkgo Biloba Products and NIST Ginkgo Reference Standard by LC/UV/MS. Experimental Biology, April 25, 2007, Washington, D.C.Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration

- (Peer Reviewed Journal)Park, J.B., Chen, P. 2007. Synthesis of safflomide and its HPLC measurement in mouse plasma after oral administration. Journal of Chromatography B: Biomedical Applications. 852(1-2):398-402.Comparison of the Terpene Lactones and Flavonols Contents in Ginkgo Biloba Commercial Samples and the NIST Standard Reference Materials Using LC/UV/MS

- (Peer Reviewed Journal)Ozcan, M., McAuley, B., and Chen, P. 2007. Comparison of the Terpene Lactones and Flavonols Contents in Ginkgo Biloba Commercial Samples and the NIST Standard Reference Materials Using LC/UV/MS. Journal of Food and Drug Analysis. 15(1):55-62LC/UV/MS-MRM for the simultaneous determination of water-soluble vitamins in multi-vitamin dietary supplements

- (Peer Reviewed Journal)Chen, P., Wolf, W.R. 2006. LC/UV/MS-MRM for the simultaneous determination of water-soluble vitamins in multi-vitamin dietary supplements. Analytical and Bioanalytical Chemistry, 387(7):2441-2448.Development and Validation of a High-Throughput Based on Liquid Chromatography with UV/MS Detection Method for Quantitation of Cichoric Acid in Echinacea purpurea Aerial-Based Dietary Supplements

- (Peer Reviewed Journal)Chen, P., Wolf, W.R. 2006. Development and Validation of a High-Throughput Based on Liquid Chromatography with UV/MS Detection Method for Quantitation of Cichoric Acid in Echinacea purpurea Aerial-Based Dietary Supplements. Journal of Association of Official Analytical Chemists International. 89:(3)612-618.DEVELOPMENT OF AN EFFICIENT, SCALABLE, ALDOLASE-CATALYZED PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF STATIN INTERMEDIATES

- (Proceedings)Greenberg, W.A., Varvak, A., Hanson, S.R., Wong, K., Huang, H., Chen, P., Burk, M.J. 2004. Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates. #89158. 101(16):5788-5793.CREATION OF A PRODUCTIVE, HIGHLY ENANTIOSELECTIVE NITRILASE THROUGH GENE SITE SATURATION MUTAGENESIS (GSSM)

- (Proceedings)Greenberg, W.A., Varvak, A., Hanson, S.R., Wong, K., Huang, H., Chen, P., Burk, M.J. 2004. Creation of a productive, highly enantioselective nitrilase through gene site saturation mutagenesis (GSSM). Proceedings of the National Academy of Sciences. 101(16):5788-5793.
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