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ARS Home Northeast Area Boston, Massachusetts People & Locations







Derek R Fisher
                        Boston, Massachusetts

                        




                        
                        Biologist
                        Phone: (617) 556-3188
                        
                        
                        Fax: (617) 556-3222(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            **Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Effects of HZE particle exposure location and energy on brain inflammation and oxidative stress in rats
                                                        

- (Peer Reviewed Journal)Cahoon, D., Rabin, B., Fisher, D.R., Shukitt Hale, B. 2023. Effects of HZE particle exposure location and energy on brain inflammation and oxidative stress in rats. Radiation Research. 200(5):431-443. https://doi.org/10.1667/RADE-22-00041.1.Extracts from green leafy vegetables and berries, and their major polyphenolics, reduce inflammatory stress signals in HAPI rat microglial cells, in vitro

- (Abstract Only)Fisher, D.R., Marschall, S.N., Zheng, T., Shukitt Hale, B. 2023. Extracts from green leafy vegetables and berries, and their major polyphenolics, reduce inflammatory stress signals in HAPI rat microglial cells, in vitro. [Abstract] Society for Neuroscience Meeting 2023. Program #PSTR203.17.Red raspberry supplemented serum reduces inflammatory stress signals in HAPI rat microglial cells, in vitro
                                                        

- (Abstract Only)Fisher, D.R., Piccolo, F.X., Xiao, D., Burton-Freeman, B.M., Shukitt Hale, B. 2023. Red raspberry supplemented serum reduces inflammatory stress signals in HAPI rat microglial cells, in vitro. [Abstract]. 7(Suppl 1):101220. https://doi.org/10.1016/j.cdnut.2023.101220.In Vitro Effects of Myo-Inositol Supplementation on Adult Human Neural Progenitor Cells
                                                        

- (Abstract Only)Mykyten, K., Fisher, D.R., Biederer, T., Zheng, T. 2023. In Vitro Effects of Myo-Inositol Supplementation on Adult Human Neural Progenitor Cells. [Abstract].  7(Suppl 1):101233. https://doi.org/10.1016/j.cdnut.2023.101233.Dietary blueberry before and/or after stressor exposure attenuates neuroinflammation, oxidative stress, and cognitive deficits in rats

- (Abstract Only)Phytochemical combination is more effective than individual components in reducing stress signaling in rat hippocampal neurons and microglia
                                                        

- (Peer Reviewed Journal)Fisher, D.R., Zheng, T., Bielinski, D.F., Kelly, M.E., Cahoon, D.S., Shukitt Hale, B. 2022. Phytochemical combination is more effective than individual components in reducing stress signaling in rat hippocampal neurons and microglia. International Journal of Molecular Sciences. 23(20):12651. https://doi.org/10.3390/ijms232012651.Protective effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells
                                                        

- (Peer Reviewed Journal)Zheng, T., Bielinski, D.F., Fisher, D.R., Zhang, J., Shukitt Hale, B. 2022. Protective effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells. Molecules. 27(19):6152. https://doi.org/10.3390/molecules27196152.Raspberry phenolics in serum from supplemented adults reduce inflammatory stress signals in HAPI rat microglial cells, in vitro

- (Abstract Only)Fisher, D.R., Piccolo, F.X., Xiao, M., Burton-Freeman, B., Shukitt Hale, B. 2022. Raspberry phenolics in serum from supplemented adults reduce inflammatory stress signals in HAPI rat microglial cells, in vitro [abstract]. Society for Neuroscience Abstracts 2022. Program No. 621.10.Dietary blueberry before and/or after exposure to HZE particles attenuates neuroinflammation, oxidative stress, and cognitive deficits in rats

- (Abstract Only)Cahoon, D.S., Fisher, D.R., Zheng, T., Rabin, B.M., Shukitt Hale, B. 2022. Dietary blueberry before and/or after exposure to HZE particles attenuates neuroinflammation, oxidative stress, and cognitive deficits in rats [abstract]. Virtual Online NASA Human Research Program Investigators Workshop. Abstract #1133-000326.Blueberry treatment administered before and/or after lipopolysaccharide stimulation and oxidative stress in rat microglial cells
                                                        

- (Peer Reviewed Journal)Cahoon, D.S., Fisher, D.R., Lamon-Fava, S., Wu, D., Zheng, T., Shukitt Hale, B. 2022. Blueberry treatment administered before and/or after lipopolysaccharide stimulation and oxidative stress in rat microglial cells. Nutritional Neuroscience. 26:127-137. https://doi.org/10.1080/1028415X.2021.2020404.Blueberry extract attenuates neuroinflammation and oxidative stress when administered before and/or after lipopolysaccharide in rat microglial cells

- (Abstract Only)Cahoon, D., Fisher, D.R., Shukitt Hale, B. 2021. Blueberry extract attenuates neuroinflammation and oxidative stress when administered before and/or after lipopolysaccharide in rat microglial cells. [abstract]. 2021 Society for Neuroscience Annual Meeting. Program #181.07.Walnut oil and blueberry treatments have beneficial individual but not synergistic effects on neuroinflammation in vitro
                                                        

- (Abstract Only)Fisher, D.R., Cahoon, D., Shukitt Hale, B. 2021. Walnut oil and blueberry treatments have beneficial individual but not synergistic effects on neuroinflammation in vitro. Current Developments in Nutrition. 5(Suppl 2):904. https://doi.org/10.1093/cdn/nzab049_017.Blueberry treatment administered before and/or after lipopolysaccharide attenuates neuroinflammation and oxidative stress in rat microglial cells
                                                        

- (Abstract Only)Cahoon, D., Fisher, D.R., Shukitt Hale, B. 2021. Blueberry treatment administered before and/or after lipopolysaccharide attenuates neuroinflammation and oxidative stress in rat microglial cells. Current Developments in Nutrition. 5(Suppl 2):899. https://doi.org/10.1093/cdn/nzab049_012.Blueberries and insulin protect microglial cells against high glucose-induced inflammation and restore GLUT-1
                                                        

- (Peer Reviewed Journal)Hininger-Favier, I., Thangthaeng, N., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B., Poulose, S.M. 2021. Blueberries and insulin protect microglial cells against high glucose-induced inflammation and restore GLUT-1. Journal of Berry Research. 11(2):201-216. https://doi.org/10.3233/JBR-200628.Beneficial effects of blueberry extracts on adult human neural progenitor cells

- (Abstract Only)Bielinski, D.F., Fisher, D.R., Shukitt Hale, B., Zheng, T. 2020. Beneficial effects of blueberry extracts on adult human neural progenitor cells. Current Developments in Nutrition. 4(Suppl_2):1191. https://meeting.nutrition.org.The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling

- (Abstract Only)Rutledge, G.A., Fisher, D.R., Miller, M.G., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2020. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling [abstract]. Program book for Translational Research Day, Poster #20, p. 14.The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro
                                                        

- (Peer Reviewed Journal)Rutledge, G.A., Fisher, D.R., Miller, M.G., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2019. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. Food and Function. 10(12):7707-7713. https://doi.org/10.1039/C9FO01913H.Walnut-associated fatty acids inhibit LPS-induced activation of BV-2 microglia

- (Peer Reviewed Journal)Carey, A.N., Fisher, D.R., Bielinski, D.F., Cahoon, D.S., Shukitt Hale, B. 2020. Walnut-associated fatty acids inhibit LPS-induced activation of BV-2 microglia. Inflammation. 43(1):241-250.Individual and synergistic effects of walnut oil and blueberry treatments on reducing neuroinflammation in rat microglial cells in vitro

- (Abstract Only)Fisher, D.R., Cahoon, D.S., Shukitt Hale, B. 2020. Individual and synergistic effects of walnut oil and blueberry treatments on reducing neuroinflammation in rat microglial cells in vitro [abstract]. Society for Neuroscience Abstracts and Proceedings. 2019 Society for Neuroscience Annual Meeting Program # 208.13.Factors involved in the beneficial effects of polyphenols on neurochemical and behavioral changes in aging

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Fisher, D.R., Rutledge, G.A., Bielinski, D.F., Scott, T.M. 2019. Factors involved in the beneficial effects of polyphenols on neurochemical and behavioral changes in aging [abstract]. ICoFF2019 program book, Abstract #SY21-4, p. 49.Serum from aged humans supplemented with blueberry or strawberry reduces inflammatory stress signals in HAPI rat microglial cells, in vitro

- (Abstract Only)Rutledge, G.A., Fisher, D.R., Miller, M.G., Thangthaeng, N., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2019. Serum from aged humans supplemented with blueberry or strawberry reduces inflammatory stress signals in HAPI rat microglial cells, in vitro [abstract]. 2019 Berry Health Benefits Symposium Pre-Proceedings, p.87.Blueberries improve neuroinflammation and cognition differentially depending on individual cognitive baseline status
                                                        

- (Peer Reviewed Journal)Shukitt Hale, B., Nopporn, T., Miller, M.G., Poulose, S.M., Fisher, D.R. 2019. Blueberries improve neuroinflammation and cognition differentially depending on individual cognitive baseline status. Journal of Gerontology Biological Science. https://doi.org/10.1093/gerona/glz048.The effects of intermittent wild blueberry feeding on inflammation and motor and cognitive behavior

- (Abstract Only)Fisher, D.R., Cahoon, D., Miller, M.G., Bielinski, D.F., Shukitt Hale, B. 2018. The effects of intermittent wild blueberry feeding on inflammation and motor and cognitive behavior [abstract]. 2018 Society for Neuroscience Annual Meeting Program # 291.17.In vitro effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells

- (Abstract Only)Zheng, T., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B., Steindler, D.A. 2018. In vitro effects of a polyphenol-rich blueberry extract on adult human neural progenitor cells [abstract]. 2018 Society for Neuroscience Annual Meeting Program # 291.16.Berry polyphenols are associated with enhanced cognition and reduced inflammation in healthy, older adults

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Fisher, D.R., Bielinski, D.F., Scott, T.M. 2018. Berry polyphenols are associated with enhanced cognition and reduced inflammation in healthy, older adults [abstract]. 256th American Chemical Society National Meeting & Exposition Program #AGFD 21.Berry fruit differentially improves age-related decrements in behavior based on baseline status

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Bielinski, D.F., Fisher, D.R. 2018. Berry fruit differentially improves age-related decrements in behavior based on baseline status [abstract]. American Chemical Society Abstracts. 256th American Chemical Society National Meeting & Exposition Program. #AGFD 24.Dietary intervention with blueberries and Epidiferphane (EDP) enhances calcium buffering in rat hippocampal neurons and reduces stress signaling in microglial cells

- (Abstract Only)Shukitt Hale, B., Fisher, D.R., Bielinski, D.F., Steindler, D., Zheng, T. 2018. Dietary intervention with blueberries and Epidiferphane (EDP) enhances calcium buffering in rat hippocampal neurons and reduces stress signaling in microglial cells [abstract]. Current Developments in Nutrition. 2(11):nzy043.Walnut extract modulates activation of microglia through alteration in intracellular calcium concentration
                                                        

- (Peer Reviewed Journal)Thangthaeng, N., Poulose, S., Fisher, D.R., Shukitt Hale, B. 2017. Walnut extract modulates activation of microglia through alteration in intracellular calcium concentration. Nutrition Research. 49:88-95. https://doi.org/10.1016/j.nutres.2017.10.016.Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high fat diet
                                                        

- (Peer Reviewed Journal)Carey, A.N., Gildawie, K.R., Rovnak, A., Thangthaeng, N., Fisher, D.R., Shukitt Hale, B. 2017. Blueberry supplementation attenuates microglia activation and increases neuroplasticity in mice consuming a high fat diet. Nutritional Neuroscience. https://doi.org/10.1080/1028415X.2017.1411875.The relationship between berry polyphenols, inflammation, and cognitive function in older adults

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Sandhu, A.K., Fisher, D.R., Scott, T.M., Burton-Freeman, B. 2017. The relationship between berry polyphenols, inflammation, and cognitive function in older adults [abstract]. E:\Papers\174-TopR-118.pdf.Effect of blueberry and insulin on glucose-induced neurotoxicity in rat microglial cells

- (Abstract Only)Hininger, I., Thangthaeng, N., Bielinski, D., Fisher, D.R., Shukitt Hale, B., Poulose, S. 2017. Effect of blueberry and insulin on glucose-induced neurotoxicity in rat microglial cells. 8th International Conference on Polyphenols and Health (ICPH 2017) Abstract# 03-053.Blueberry and EpidiferphaneTM (EDP) enhance calcium buffering in rat hippocampal cells and reduce stress signalling in microglial cells

- (Abstract Only)Fisher, D.R., Zheng, T., Bielinski, D.F., Steindler, D., Shukitt Hale, B. 2017. Blueberry and EpidiferphaneTM (EDP) enhance calcium buffering in rat hippocampal cells and reduce stress signalling in microglial cells. Society for Neuroscience Abstracts and Proceedings. Program #667.15.In vitro effects of EpidiferphaneTM on adult human neural progenitor cells

- (Abstract Only)Zheng, T., Bielinski, D., Fisher, D.R., Shukitt Hale, B., Reynolds, B., Steindler, D. 2017. In vitro effects of EpidiferphaneTM on adult human neural progenitor cells. Society for Neuroscience Abstracts and Proceedings. Program #667.14.The relationship between anthocyanins found in berry fruit, inflammation, and cognitive function in older adults

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Sandhu, A., Burton-Freeman, B. 2017. The relationship between anthocyanins found in berry fruit, inflammation, and cognitive function in older adults [abstract]. 9th International Workshop on Anthocyanins. p. 16.Effects of blueberries on inflammation, motor performance and cognitive function

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Kelly, M.E., Scott, T. 2017. Effects of blueberries on inflammation, motor performance and cognitive function [abstract]. 21st International Association of Gerontology & Geriatrics (IAGG) World Congress, July 23-27, 2017, San Francisco, CA. doi:https://doi.org/10.1093/geroni/igx004.5010.Tart cherry extracts reduce inflammatory and oxidative stress signaling in microglial cells

- (Peer Reviewed Journal)Shukitt Hale, B., Kelly, M.E., Bielinski, D.F., Fisher, D.R. 2016. Tart cherry extracts reduce inflammatory and oxidative stress signaling in microglial cells. Antioxidants. doi: 10.3390/antiox5040033.The beneficial effects of berry fruit on cognitive and neuronal function in aging

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Kelly, M.E., Scott, T. 2016. The beneficial effects of berry fruit on cognitive and neuronal function in aging. In: Proceedings of the 20th International Conference. Functional and Medical Foods for Chronic Diseases:Bioactive Compounds and Biomarkers, September 22-23, 2016, Boston, Massachusetts. p. 289-290.The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro

- (Abstract Only)Fisher, D.R., Miller, M.G., Thangthaeng, N., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2016. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. Society for Neurscience 2016 Abstracts. Program No. 596.19.The effects of blueberries on cognition and neuroplasticity

- (Abstract Only)Carey, A.N., Rovnak, A.M., Gildawie, K.R., Fisher, D.R., Shukitt Hale, B. 2016. The effects of blueberries on cognition and neuroplasticity. [abstract]. 252nd American Chemical Society National Meeting, Program #AGFD 161.Berry fruit can improve age-associated neuronal and cognitive deficits: from the laboratory to the clinic

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Thangthaeng, N., Fisher, D.R., Bielinski, D., Kelly, M.E., Tammy, S. 2016. Berry fruit can improve age-associated neuronal and cognitive deficits: from the laboratory to the clinic. American Aging Association. 72:61.Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells

- (Peer Reviewed Journal)Carey, A., Miller, M.G., Fisher, D.R., Bielinski, D., Gilman, C.K., Poulose, S.M., Shukitt Hale, B. 2017. Dietary supplementation with the polyphenol-rich açaí pulps (Euterpe oleracea Mart. and Euterpe precatoria Mart.) improves cognition in aged rats and attenuates inflammatory signaling in BV-2 microglial cells. Nutritional Neuroscience. 20:238-245.Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status

- (Abstract Only)Thangthaeng, N., Miller, M.G., Poulose, S.M., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B. 2015. Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status. Society for Neuroscience Abstracts and Proceedings. Society for Neuroscience Abstracts 2015, Program #767.03.Walnuts improve neuronal and behavioral function in aging

- (Abstract Only)Shukitt Hale, B., Thangthaeng, N., Fisher, D.R., Bielinski, D.F., Poulose, S.M. 2015. Walnuts improve neuronal and behavioral function in aging. Federation of European Nutrition Societies European Nutrition Conference. Annals of Nutrition and Metabolism.  Vol. 67 (Suppl. 1) p. 463.Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status

- (Abstract Only)Miller, M.G., Fisher, D.R., Kelly, M.E., Bielinski, D.F., Shukitt Hale, B. 2015. Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status. Federation of American Societies for Experimental Biology Conference. 29:900.2.Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition

- (Abstract Only)Thangthaeng, N., Miller, M.G., Poulose, S.M., Bielinski, D.F., Fisher, D.R., Shukitt Hale, B. 2015. Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition. Federation of American Societies for Experimental Biology Conference. 29:756-758.Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in BV-2 microglial cells

- (Peer Reviewed Journal)Fisher, D.R., Poulose, S.M., Bielinski, D.F., Shukitt Hale, B. 2014. Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in BV-2 microglial cells. Nutritional Neuroscience. 20(2):103-109.  doi: 10.1179/1476830514Y.0000000150.Tart cherry extracts reduce inflammatory stress signaling and enhance calcium buffering in microglial and neuronal cell lines

- (Abstract Only)Fisher, D.R., Bielinski, D., Kelly, M.E., Shukitt Hale, B. 2014. Tart cherry extracts reduce inflammatory stress signaling and enhance calcium buffering in microglial and neuronal cell lines. Society for Neuroscience Abstracts and Proceedings 2014. Program #144.18.Serum metabolites from blueberry-supplemented older adults attenuate stress-induced neurotoxicity in HAPI microglial cells dependent on baseline cognitive status

- (Abstract Only)Shukitt Hale, B., Miller, M.G., Fisher, D.R. 2014. Serum metabolites from blueberry-supplemented older adults attenuate stress-induced neurotoxicity in HAPI microglial cells dependent on baseline cognitive status. Society for Neuroscience Abstracts and Proceedings. 2014. Program #144.16.Walnut extracts protect cultured microglia against LPS-induced neurotoxicity via modulation of intracellular calcium concentration

- (Abstract Only)Thangthaeng, N., Poulose, S., Fisher, D.R., Shukitt Hale, B. 2014. Walnut extracts protect cultured microglia against LPS-induced neurotoxicity via modulation of intracellular calcium concentration. Society for Neuroscience Abstracts and Proceedings. 2014. Program #144.17.Differential protective effects of serum metabolites from young and old walnut-fed rats against stress-induced neurotoxicity in BV-2 microglial cells

- (Abstract Only)Shukitt Hale, B., Fisher, D.R., Bielinski, D.F., Poulose, S.M. 2014. Differential protective effects of serum metabolites from young and old walnut-fed rats against stress-induced neurotoxicity in BV-2 microglial cells. [abstract]. American Aging Association. 127:73.Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich acai (Euterpe sps.) fruit pulp extracts in rodent brain cells in vitro

- (Peer Reviewed Journal)Poulose, S.M., Fisher, D.R., Bielinski, D., Gomes, S., Rimando, A., Schauss, A., Shukitt Hale, B. 2014. Restoration of stressor-induced calcium dysregulation and autophagy inhibition by polyphenol-rich acai (Euterpe sps.) fruit pulp extracts in rodent brain cells in vitro. Nutrition. 30: 853-862.Dietery acai fruit improves cognition in aged rats

- (Abstract Only)Miller, M.G., Fisher, D.R., Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2013. Dietery acai fruit improves cognition in aged rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program # 252.04.Dietery walnut alters neurochemical and behavioral functions in young and old rats

- (Abstract Only)Poulose, S.M., Fisher, D.R., Miller, M.M., Bielinski, D.F., Ramirez, F., Shukitt Hale, B. 2013. Dietery walnut alters neurochemical and behavioral functions in young and old rats. Society for Neuroscience Abstracts and Proceedings. 2013. Program #252.02.Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia

- (Peer Reviewed Journal)Carey, A.N., Fisher, D.R., Rimando, A.M., Gomes, S.M., Bielinski, D.F., Shukitt Hale, B. 2013. Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia. Journal of Agricultural and Food Chemistry. 61: 5979-5986.Dietary acai fruit improves cognition and mobility in aged rats

- (Abstract Only)Miller, M.G., Fisher, D.R., Carey, A.N., Poulose, S.M., Shukitt Hale, B. 2013. Dietary acai fruit improves cognition and mobility in aged rats. Federation of American Societies for Experimental Biology Conference. Abstract 27:1083.3.Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in brain cells in vitro

- (Abstract Only)Poulose, S.M., Fisher, D.R., Bielinski, D., Shukitt Hale, B. 2012. Serum metabolites from walnut-fed aged rats attenuate stress-induced neurotoxicity in brain cells in vitro [abstract]. Society for Neuroscience Abstracts and Proceedings. Paper No. 865:02.The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells

- (Peer Reviewed Journal)Carey, A.N., Fisher, D.R., Joseph, J.J., Shukitt Hale, B. 2013. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. Nutritional Neuroscience. 16(1):13-20.Anthocyanin-rich acai (Euterpe oleracea mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells

- (Peer Reviewed Journal)Poulose, S.M., Fisher, D.R., Larson, J., Bielinski, D.F., Rimando, A.M., Carey, A.N., Schauss, A.G., Shukitt Hale, B. 2012. Anthocyanin-rich acai (Euterpe oleracea mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells. Journal of Agricultural and Food Chemistry. 60:1084-1093.Differential protection among fractionated blueberry polyphenolic families against DA-, ABeta 42 and LPS-induced decrements in Ca2+ buffering in primary hippocampal cells

- (Peer Reviewed Journal)Joseph, J.A., Shukitt Hale, B., Brewer, G.J., Weikel, K.A., Kalt, W., Fisher, D.R. 2010. Differential protection among fractionated blueberry polyphenolic families against DA-, ABeta 42 and LPS-induced decrements in Ca2+ buffering in primary hippocampal cells. Journal of Agriculture and Food Chemistry. 58:8196-8204.Walnut extract inhibits LPS-induced activation of BV-2 microglia via internalization of TLR4: possible involvement of phospholipase D2

- (Peer Reviewed Journal)Willis, L., Bielinski, D.F., Fisher, D.R., Matthan, N.R., Joseph, J.A. 2010. Walnut extract inhibits LPS-induced activation of BV-2 microglia via internalization of TLR4: possible involvement of phospholipase D2. Inflammation. 33(5):325.Blueberry antagonism of C-2 ceramide disruption of Ca2+ responses and recovery in MAChR-transfected COS-7 cells involves alterations in stress signaling

- (Peer Reviewed Journal)Joseph, J.A., Bielinski, D., Fisher, D.R. 2010. Blueberry antagonism of C-2 ceramide disruption of Ca2+ responses and recovery in MAChR-transfected COS-7 cells involves alterations in stress signaling. Journal of Agricultural Food & Chemistry. 58:3380-3392.Cellular and Behavioral Effects of Stilbene Resveratrol Analogs: Implications for Reducing the Deleterious Effects of Aging

- (Peer Reviewed Journal)Joseph, J.A., Fisher, D.R., Cheng, V., Rimando, A.M., Shukitt Hale, B. 2008. Cellular and Behavioral Effects of Stilbene Resveratrol Analogs: Implications for Reducing the Deleterious Effects of Aging. Journal of Agriculture and Food Chemistry.56(22)10544-10551.Blueberry Antagonism of C-2 Ceramide Disruption of CA2+ Responses and Recovery in MAChR-Transfected COS-7 Cells

- (Peer Reviewed Journal)Joseph, J.A., Neuman, A., Bielinski, D.F., Fisher, D.R. 2008. Blueberry Antagonism of C-2 Ceramide Disruption of CA2+ Responses and Recovery in MAChR-Transfected COS-7 Cells. Journal of Alzheimer's Disease.15:429-441.Cytoprotective effects of anthocyanins and other phenolic fractions of Boysenberry and blackcurrant on dopamine and amyloid Beta induced oxidative stress in transfected COS-7 cells

- (Peer Reviewed Journal)Ghosh, D., Mcghie, T.K., Fisher, D.R., Joseph, J.A. 2007. Cytoprotective effects of anthocyanins and other phenolic fractions of Boysenberry and blackcurrant on dopamine and amyloid Beta induced oxidative stress in transfected COS-7 cells. Journal of the Science of Food and Agriculture. 87:2061-2067.Dopamine and ABeta-induced Stress Signaling and Decrements in CA2+ Buffering in Primary Neonatal Hippocampal Cells are Antagonized by Blueberry Extract

- (Peer Reviewed Journal)Joseph, J.A., Carey, A.N., Brewer, G.J., Lau, F.C., Fisher, D.R. 2007. Dopamine and ABeta-induced Stress Signaling and Decrements in CA2+ Buffering in Primary Neonatal Hippocampal Cells are Antagonized by Blueberry Extract. Journal of Alzheimer's Disease. 11:433-446.Dopamine-Induced Stress Signaling in COS-7 Cells Transfected With Selectively Vulnerable Muscarinic Receptor Subtypes is Partially Mediated Via the i3 Loop and Antagonized By Blueberry Extract

- (Peer Reviewed Journal)Joseph, J.A., Fisher, D.R., Carey, A.N., Bielinski, D.F. 2006. Dopamine-Induced Stress Signaling in COS-7 Cells Transfected With Selectively Vulnerable Muscarinic Receptor Subtypes is Partially Mediated Via the i3 Loop and Antagonized By Blueberry Extract. Journal of Alzheimer's Disease. 10:423-437.BLUEBERRY EXTRACT ALTERS OXIDATIVE STRESS-MEDIATED SIGNALING IN COS-7 CELLS TRANSFECTED WITH SELECTIVELY VULNERABLE MUSCARINIC RECEPTOR SUBTYPES

- (Peer Reviewed Journal)Joseph, J.A., Fisher, D.R., Bielinski, D. 2006. Blueberry extract alters oxidative stress-mediated signaling in cos-7 cells transfected with selectively vulnerable muscarinic receptor subtypes. Journal of Alzheimer's Disease. 9(1):35-42.BLUEBERRY EXTRACT INHIBITS DA-OR AB-INDUCED DECREMENTS IN CALCIUM FLUX IN PRIMARY HIPPOCAMPAL CELLS

- (Abstract Only)Joseph, J.A., Fisher, D.R. 2005. Blueberry extract inhibits da-or ab-induced decrements in calcium flux in primary hippocampal cells. Society for Neuroscience Abstracts and Proceedings. Abstract No. 93.6.BLUEBERRY EXTRACT PREVENTS C-2 CERAMIDE DISRUPTION OF CA2+ BUFFERING IN MACHR-TRANSFECTED COS-7 CELLS

- (Abstract Only)Fisher, D.R., Bielinski, D.F., Joseph, J.A. 2005. Blueberry extract prevents c-2 ceramide disruption of ca2+ buffering in machr-transfected cos-7 cells. Society for Neuroscience Abstracts and Proceedings. Abstract No. 93.7OXIDATIVE STRESS AND INFLAMMATION IN BRAIN AGING: NUTRITIONAL CONSIDERATIONS

- (Review Article)Joseph, J.A., Shukitt Hale, B., Casadesus, G., Fisher, D.R. 2005. Oxidative stress and inflammation in brain aging: nutritional considerations. Neurochemical Research. Volume(30):927-935BLUEBERRY EXTRACT INHIBITS DA-INDUCED INCREASES IN MAPK SIGNALING IN MUSCARINIC M1 AND M3-TRANSFECTED COS-7 CELLS

- (Proceedings)Joseph, J.A., Bielinski, D., Fisher, D.R. 2004. Blueberry extract inhibits DA-induced increases in MAPK signaling in Muscarinic M1 and M3-transfected COS-7 cells. Soc.Neurosci. Abs. 2004, 30, 1017.17.THE M3 MUSCARINIC RECEPTOR I3 DOMAIN CONFERS OXIDATIVE STRESS PROTECTION ON CALCIUM REGULATION IN TRANSFECTED COS-7 CELLS

- (Peer Reviewed Journal)Joseph, J.A., Fisher, D.R., Carey, A.N., Szprengiel, A. 2004. The m3 muscarinic receptor i3 domain confers oxidative stress protection on calcium regulation in transfected cos-7 cells. Aging Cell (2004)3, pp263-271.FRUIT EXTRACTS ANTAGONIZE AB-OR DA-INDUCED DEFICITS IN CA2+ FLUX IN M1-TRANSFECTED COS-7 CELLS

- (Peer Reviewed Journal)Joseph, J.A., Fisher, D.R., Carey, A.N. 2004. Fruit extracts antagonize ab-or da-induced deficits in ca2+ flux in m1-transfected cos-7 cells. Journal of Alzheimer's Disease 6(2004) 403-411.MUSCARININC RECEPTOR SUBTYPE DETERMINES VULNERABILITY TO AMYLOD BETA TOXICITY IN TRANSFECTED COS-7 CELLS

- (Peer Reviewed Journal)Joseph, J.A., and Fisher, D.R.  Muscarinic receptor subtype determines vulnerability to amyloid beta  toxicity in transfected COS 7 cells. J. Alz. Dis. 2003. 5: 197-208.MUSCARINIC RECEPTOR SUBTYPE DETERMINES VULNERABILITY TO OXIDATIVE STRESS IN COS-7 CELLS

- (Peer Reviewed Journal)Joseph, J.A., Fisher, D.R., and Strain, J. Muscarinic receptor subtype determines vulnerability to oxidative stress in COS-7 cells. Free Rad. Biol. Med.  2002, 32: 153-161.


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