|   | 1.                                                     I have reviewed this report on Form 10-K of CNS Response, Inc.      for the year ended September 30,2010; |
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|   | 2.                                                     Based on my knowledge, this report does not contain any untrue      statement of a material fact or omit to state a material fact necessary to      make the statements made, in light of the circumstances under which such      statements were made, not misleading with respect to the period covered by      this report; |
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|   | 3.                                                     Based on my knowledge, the financial statements, and other      financial information included in this report, fairly present in all      material respects the financial condition, results of operations and cash      flows of the registrant as of, and for, the periods presented in this      report; |
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|   | 4.                                                     The registrant’s other certifying officer(s) and I are      responsible for establishing and maintaining disclosure controls and      procedures (as defined in Exchange Act Rules 13a-15(e) and      15d-15(e)) and internal control over financial reporting (as defined in      Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant      and have: |
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|   | (a)                                                Designed such disclosure controls and procedures, or caused such      disclosure controls and procedures to be designed under our supervision,      to ensure that material information relating to the registrant, including      its consolidated subsidiaries, is made known to us by others within those      entities, particularly during the period in which this report is being      prepared; |
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|   | (b)                                               Designed such internal control over financial reporting, or caused      such internal control over financial reporting to be designed under our      supervision, to provide reasonable assurance regarding the reliability of      financial reporting and the preparation of financial statement for      external purposes in accordance with generally accepted accounting      principles; |
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|   | (c)                                                Evaluated the effectiveness of the registrant’s disclosure controls      and procedures and presented in this report our conclusions about the      effectiveness of the disclosure controls and procedures, as of the end of      the period covered by this report based on such evaluation;      and |
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|   | (d)                                               Disclosed in this report any change in the registrant’s internal      control over financial reporting that occurred during the registrant’s      most recent fiscal quarter (the registrant’s fourth fiscal quarter in the      case of an annual report) that has materially affected, or is reasonably      likely to materially affect, the registrant’s internal control over      financial reporting; and |
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|   | 5.                                                     The registrant’s other certifying officer(s) and I have      disclosed, based on our most recent evaluation of internal control over      financial reporting, to the registrant’s auditors and the audit committee      of the registrant’s board of directors (or persons performing the      equivalent functions): |
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|   | (a)                                                All significant deficiencies and material weaknesses in the design      or operation of internal control over financial reporting which are      reasonably likely to adversely affect the registrant’s ability to record,      process, summarize and report financial information;  and |
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|   | (b)                                               Any fraud, whether or not material, that involves management or      other employees who have a significant role in the registrant’s internal      control over financial reporting. |
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| Dated:  December      20, 2010 | /s/      George Carpenter           |
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|                                     | Name: George      Carpenter         |
|                                     | Title: Chief Executive      Officer |