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                    U.S. DEPARTMENT OF AGRICULTURE
 Microbiome and Metabolism Research Unit: Little Rock, AR
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ARS Home Southeast Area Little Rock, Arkansas Microbiome and Metabolism Research Unit People & Locations







Laxmi  Yeruva

                                                                (PhD)
                        Microbiome and Metabolism Research Unit

                        




                        
                        Research Leader
                        Phone: (501) 364-2419
                        
                        
                        Fax: (501) 364-2403(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsEarly Life Factors and Microbiota Impact on Healthy Development
                                                    In-House Appropriated
                                                                    (D)Accession Number: 445369Network Service Agreement for ARS - Nutrition Center Location
                                                    Non-Funded Cooperative Agreement
                                                                    (N)Accession Number: 444104Research to Understand How Maternal-Child Nutrition and Physical Activity Optimize Health and Development
                                                    Non-Funded Cooperative Agreement
                                                                    (N)Accession Number: 440470Utilizing the University of Arkansas Medical Sciences Animal Care and Use Committee and the Institutional Biosafety Committee
                                                    Non-Funded Cooperative Agreement
                                                                    (N)Accession Number: 441566Impact of Prenatal and Postnatal Factors on Mother and Child Health
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 441948Impact of Prenatal and Postnatal Factors on Mother and Child Health
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 443495Impact of Prenatal and Postnatal Factors on Mother and Child Health
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 444102Dietary and Physical Activity Influences on Infant/Child/Adolescent/Maternal Health and Development
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 439549**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Apiaceous Vegetables Improved Gut Dysbiosis Induced by Dextran Sodium Sulfate in mice consuming Total Western Diet

- (Abstract Only)Single-cell RNA sequencing reveals that breastfeeding shapes IL-4 and IL-13 signaling in neonatal peripheral blood mononuclear cells.

- (Abstract Only)Maternal immune cell gene expression during gestation associates with infant gut microbiota composition

- (Abstract Only)Human milk oligosaccharides and Bifidobacteria infantis interactively shape mouse splenic immune responses.

- (Abstract Only)Effects of early life stress on skeletal health

- (Abstract Only)Microbiota of infants consuming secretors or non-secretors mothers milk impacts gut and immune system in mice
                                                        

- (Peer Reviewed Journal)Gurung, M., Schlegel, B., Rajasundaram, D., Fox, R., Bode, L., Lindemann, S.R., Leroith, T., Read, Q.D., Simecka, C., Carol, L., Andres, A., Yeruva, V. 2024. Microbiota of infants consuming secretors or non-secretors mothers milk impacts gut and immune system in mice. mSystems. https://doi.org/10.1128/msystems.00294-24.Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis Type-2 Diabetes Mellitus Rats

- (Peer Reviewed Journal)The Role of Early-Life Gut Mycobiome on Child Health
                                                        

- (Peer Reviewed Journal)Rodriguez, K.A., Gurung, M., Talatala, R., Rearick, J.R., Ruebel, M., Stephens, K.E., Yeruva, V. 2024. The Role of Early-Life Gut Mycobiome on Child Health. Advances in Nutrition. 15(3):100185. https://doi.org/10.1016/j.advnut.2024.100185.Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and body mass index
                                                        

- (Peer Reviewed Journal)Yeruva, V., Mulakala, B.K., Rajasundaram, D., Gonzalez, S., Cabrera-Rubio, R., Martinez-Costa, C., Collado, M. 2023. Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and body mass index. Clinical Nutrition. 42(12):2528-2539. https://doi.org/10.1016/j.clnu.2023.10.011.The nutritional immunology across the life span
                                                        

- (Review Article)Saame Raza, S., Crott, J., Comstock, S., Yeruva, V., Davis, T.A. 2023. The nutritional immunology across the life span. Journal of Nutrition. https://doi.org/10.1016/j.tjnut.2023.06.008.Evaluation of a plant-based infant formula containing almonds and buckwheat on gut microbiota composition, intestine mor-phology, metabolic and immune markers in a neonatal piglet model
                                                        

- (Peer Reviewed Journal)Gurung, M., Rosa, F., Yelvington, B., Terry, N., Read, Q.D., Piccolo, B., Moody, B., Tripp, P., Pittman, H., Fay, B., Ross, T., Sikes, J., Flowers, J., Fox, R., Yoseph, F., Yeruva, V., Leroith, T., Talatala, R. 2023. Evaluation of a plant-based infant formula containing almonds and buckwheat on gut microbiota composition, intestine mor-phology, metabolic and immune markers in a neonatal piglet model. Nutrients. 15(2):383. https://doi.org/10.3390/nu15020383.Human milk oligosaccharides impact cellular and inflammatory gene expression and immune response
                                                        

- (Peer Reviewed Journal)Rosa, F., Sharma, A.K., Gurung, M., Casero, D., Matazel, K., Bode, L., Simecka, C., Elolimy, A.A., Tripp, P., Randolph, C., Hand, T.W., Williams, K.D., Leroith, T., Fox, R., Yeruva, V. 2022. Human milk oligosaccharides impact cellular and inflammatory gene expression and immune response. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.907529.Evaluation of the safety of a plant-based infant formula containing almonds and buckwheat in a neonatal piglet model
                                                        

- (Peer Reviewed Journal)Rosa, F., Yelvington, B., Terry, N., Tripp, P., Pittman III, H.E., Fay, B.L., Ross, T.J., Sikes, J.D., Flowers, J.B., Yoseph, F.B., Yeruva, V. 2022. Evaluation of the safety of a plant-based infant formula containing almonds and buckwheat in a neonatal piglet model. Nutrients. https://doi.org/10.3390/nu14071499.Bacterial and fungal adaptations in cecum and distal colon of piglets fed dairy-based milk formula in comparison to human milk
                                                        

- (Peer Reviewed Journal)Elolimy, A., Rosa, F., Tripp, P., Bowlin, A.K., Randolph, C., Robeson, M., Yeruva, V. 2022. Bacterial and fungal adaptations in cecum and distal colon of piglets fed dairy-based milk formula in comparison to human milk. Frontiers in Microbiology.  https://doi.org/10.3389/fmicb.2022.801854.Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies
                                                        

- (Peer Reviewed Journal)Pace, R.M., Williams, J.E., Järvinen, K.M., Meehan, C.L., Martin, M.A., Ley, S.H., Barbosa-Leiker, C., Andres, A., Yeruva, V., Belfort, M.B., Caffe, B., Navarrete, A.D., Lackey, K.A., Pace, C., Gogel, A.C., Fehrenkamp, B.D., Klein, M., Young, B., Rosen-Carole, C., Diaz, N., Gaw, S.L., Flaherman, V., Mcguire, M.A., Mcguire, M.K., Seppo, A. 2021. Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2021.801797.Milk formula diet alters bacterial and host protein profile in comparison to human milk diet in neonatal piglet model
                                                        

- (Peer Reviewed Journal)Rosa, F., Zybailov, B., Glazko, G.V., Rahmatallah, Y., Byrum, S., Mackintosh, S.G., Bowlin, A.K., Yeruva, V. 2021. Milk formula diet alters bacterial and host protein profile in comparison to human milk diet in neonatal piglet model. Nutrients. 13(11):3718. https://doi.org/10.3390/nu13113718.Progression of diabetes is associated with changes in the ileal transcriptome and ileal-colon morphology in the UC Davis Type 2 diabetes mellitus rat
                                                        

- (Peer Reviewed Journal)Piccolo, B.D., Graham, J.L., Kang, P., Randolph, C.E., Shankar, K., Yeruva, V., Fox, R., Robeson, M.S., Moody, B., LeRoith, T., Stanhope, K.L., Adams, S.H., Havel, P.J. 2021. Progression of diabetes is associated with changes in the ileal transcriptome and ileal-colon morphology in the UC Davis Type 2 diabetes mellitus rat. Physiological Reports. 9(22):e15102. https://doi.org/10.14814/phy2.15102.


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