U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Virus and Prion Research: Ames, IA
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    CareersSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Midwest Area Ames, Iowa National Animal Disease Center Virus and Prion Research People & Locations







Amy  Baker
                        Virus and Prion Research

                        




                        
                        Research Veterinary Medical Officer
                        Phone: (515) 337-7557
                        
                        
                        Fax: (515) 337-7149(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsOnline Algorithms to Identify Reassortment and Genetic Novelty in Genomic Influenza A Virus Surveillance Data
                                                    Cooperative Agreement
                                                                    (A)Accession Number: 444740Intervention Strategies to Control Endemic and New and Emerging Influenza A Virus Infections in Swine
                                                    In-House Appropriated
                                                                    (D)Accession Number: 441145The Study of Influenza A Viruses in the Swine Host
                                                    Interagency Reimbursable Agreement
                                                                    (I)Accession Number: 437036The Study of Influenza A Viruses in the Swine Host
                                                    Interagency Reimbursable Agreement
                                                                    (I)Accession Number: 441001NIAID Centers of Excellence for Influenza Research and Response
                                                    Reimbursable Cooperative Agreement
                                                                    (R)Accession Number: 440710Transmission Bottlenecks and Within-host Evolutionary Dynamics of Influenza A Virus
                                                    Reimbursable Cooperative Agreement
                                                                    (R)Accession Number: 438621Safe and Broadly Cross-Protective Live Attenuated Influenza Virus Vaccine for Use in Swine
                                                    Reimbursable Cooperative Agreement
                                                                    (R)Accession Number: 443568mRNA-LNP Vaccines for Pandemic Preparedness
                                                    Reimbursable Cooperative Agreement
                                                                    (R)Accession Number: 444776Characterization of Influenza at the Human and Swine Interface
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 444004Algorithms to Identify Novel Influenza A Viruses in Genomic Surveillance Data
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 442620Evolution of Influenza A Virus in Swine in Brazil
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 438844**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Biomarkers associated with vaccine-associated enhanced respiratory disease following influenza A infection in swine
                                                        

- (Peer Reviewed Journal)Wymore Brand, M.J., Souza, C.K., Gauger, P., Arruda, B.L., Baker, A.L. 2024. Biomarkers associated with vaccine-associated enhanced respiratory disease following influenza A infection in swine. Veterinary Immunology and Immunopathology. https://doi.org/10.1016/j.vetimm.2024.110787.Assessment of swine H1 strains reveals a potential pandemic risk of circulating a-H1N2 viruses

- (Peer Reviewed Journal)Detection and characterization of influenza A virus endemic circulation in suckling and nursery pigs originating from vaccinated farms in the same production system
                                                        

- (Peer Reviewed Journal)Campos, A.D., Baker, A.L., Baker, R.B., Zhang, J., Zeller, M.A., Kitikoon, P., Gauger, P.C. 2024. Detection and characterization of influenza A virus endemic circulation in suckling and nursery pigs originating from vaccinated farms in the same production system. Viruses. https://doi.org/10.3390/v16040626.Divergent pathogenesis and transmission among avian and mammalian isolates of highly pathogenic avian influenza A (H5N1) in swine

- (Proceedings)Divergent Pathogenesis and Transmission of Highly Pathogenic Avian Influenza A(H5N1) in Swine
                                                        

- (Peer Reviewed Journal)Arruda, B.L., Baker, A.L., Devries, A.C., Anderson, T.K., Torachetti, M., Hines Bergeson, N., Killian, M.L., Lantz, K. 2024. Divergent pathogenesis and transmission among avian and mammalian isolates of highly pathogenic avian influenza A (H5N1) in swine. Emerging Infectious Diseases. https://doi.org/10.3201/eid3004.231141.Amino acid 138 in the HA of a H3N2 subtype influenza A virus increases affinity for the lower respiratory tract and alveolar macrophages in pigs
                                                        

- (Peer Reviewed Journal)Cardenas, M., Seibert, B., Cowan, B., Fraiha, A.S., Carnaccini, S., Gay, C.L., Faccin, F., Caceres, J.C., Anderson, T.K., Baker, A.L., Perez, D.R., Rajao, D.S. 2024. Amino acid 138 in the HA of a H3N2 subtype influenza A virus increases affinity for the lower respiratory tract and alveolar macrophages in pigs. PLoS Pathogens. https://doi.org/10.1371/journal.ppat.1012026.Nucleoprotein reassortment enhanced transmissibility of H3 1990.4.a clade influenza A virus in swine
                                                        

- (Peer Reviewed Journal)Thomas, M.N., Ciacci Zanella, G., Cowan, B., Caceres, J.C., Rajao, D.S., Perez, D.R., Gauger, P.C., Baker, A.L., Anderson, T.K. 2024. Nucleoprotein reassortment enhanced transmissibility of H3 1990.4.a clade influenza A virus in swine. Journal of Virology. https://doi.org/10.1128/jvi.01703-23.Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus
                                                        

- (Peer Reviewed Journal)Ciacci Zanella, G., Snyder, C.A., Arruda, B.L., Whitworth, K., Green, E., Poonooru, R.R., Telugu, B.P., Baker, A.L. 2024. Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus. Frontiers in Genome Editing. https://doi.org/10.3389/fgeed.2023.1320180.Human-to-swine introductions and onward transmission of 2009 H1N1 pandemic influenza viruses in Brazil
                                                        

- (Peer Reviewed Journal)Junqueira, D.M., Tochetto, C., Anderson, T.K., Gava, D., Haach, V., Cantao, M.E., Baker, A.L., Schaefer, R. 2023. Human-to-swine introductions and onward transmission of 2009 H1N1 pandemic influenza viruses in Brazil. Frontiers in Microbiology. 14. https://doi.org/10.3389/fmicb.2023.1243567.Reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine results in viruses with zoonotic potential
                                                        

- (Peer Reviewed Journal)Markin, A., Ciacci Zanella, G., Arendsee, Z.W., Zhang, J., Krueger, K.M., Gauger, P.C., Baker, A.L., Anderson, T.K. 2023. Reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine results in viruses with zoonotic potential. PLoS Pathogens. 19(7). Article e1011476. https://doi.org/10.1371/journal.ppat.1011476.Mucin 4 is a cellular biomarker of necrotizing bronchiolitis in influenza A virus infection
                                                        

- (Peer Reviewed Journal)Arruda, B.L., Kanefsky, R.A., Hau, S.J., Janzen, G.M., Anderson, T.K., Baker, A.L. 2023. Mucin 4 is a cellular biomarker of necrotizing bronchiolitis in influenza A virus infection. Microbes and Infection. e105169. https://doi.org/10.1016/j.micinf.2023.105169.PARNAS: Objectively selecting the most representative taxa on a phylogeny
                                                        

- (Peer Reviewed Journal)Markin, A., Wagle, S., Grover, S., Baker, A.L., Eulenstein, O., Anderson, T.K. 2023. PARNAS: Objectively selecting the most representative taxa on a phylogeny. Systematic Biology. esyad028. https://doi.org/10.1093/sysbio/syad028.Experimental challenge of a SARS-CoV-2 Omicron variant in American mink

- (Abstract Only)Characterizing a century of genetic diversity and contemporary antigenic diversity of N1 neuraminidase in influenza A virus from North American swine
                                                        

- (Peer Reviewed Journal)Hufnagel, D.E., Young, K.M., Arendsee, Z., Gay, L.C., Caceres, C.J., Rajao, D., Perez, D.R., Baker, A.L., Anderson, T.K. 2023. Characterizing a century of genetic diversity and contemporary antigenic diversity of N1 neuraminidase in influenza A virus from North American swine. Virus Evolution. 9(1). Article 10.1093. https://doi.org/10.1093/ve/vead015.Introductions of human-origin seasonal H3N2, H1N2, and pre-2009 H1N1 influenza viruses to swine in Brazil
                                                        

- (Peer Reviewed Journal)Tochetto, C., Junqueira, D.M., Anderson, T.K., Gava, D., Haach, V., Cantao, M.E., Baker, A.L., Schaefer, R. 2023. Introductions of human-origin seasonal H3N2, H1N2, and pre-2009 H1N1 influenza viruses to swine in Brazil. Viruses. 15(2). Article 576. https://doi.org/10.3390/v15020576.Swine-to-ferret transmission of antigenically drifted contemporary swine H3N2 influenza A virus is an indicator of zoonotic risk to humans
                                                        

- (Peer Reviewed Journal)Souza, C.K., Kimble, J.B., Anderson, T.K., Arendsee, Z.W., Hufnagel, D.E., Young, K.M., Gauger, P.C., Lewis, N.S., Davis, C.T., Sharmi, T., Baker, A.L. 2023. Swine-to-ferret transmission of antigenically drifted contemporary swine H3N2 influenza A virus is an indicator of zoonotic risk to humans. Viruses. 15(2). Article 331. https://doi.org/10.3390/v15020331.Live attenuated influenza A virus vaccine expressing an IgA-inducing protein protects pigs against replication and transmission.
                                                        

- (Peer Reviewed Journal)Rajoa, D.S., Zanella, G.C., Brand, M.W., Khan, S., Miller, M.E., Ferreri, L.M., Caceres, C., Cadernas-Garcia, S., Souza, C.K., Anderson, T.K., Gauger, P.C., Baker, A.L., Perez, D.R. 2023. Live attenuated influenza A virus vaccine expressing an IgA-inducing protein protects pigs against replication and transmission.. Frontiers in Virology. 3. Article 1042724. https://doi.org/10.3389/fviro.2023.1042724.Fine-Scale Analysis of Influenza A Virus in Swine Reveals Persistent Clade Circulation and  Limited Clade Diversity within Owners

- (Proceedings)Arruda, B.L., Neveau, M., Baker, A.L., Anderson, T.K., De-Sousa-E-Silva, G., Gauger, P.C. 2023. Fine-Scale Analysis of Influenza A Virus in Swine Reveals Persistent Clade Circulation and  Limited Clade Diversity within Owners. American Association of Swine Veterinarians Annual Meeting. American Association of Swine Veterinarians Annual Meeting, March 4-7, 2023, Aurora, Colorado.Veterinarian perceptions and practices in prevention and control of influenza virus in the midwest United States swine farms
                                                        

- (Peer Reviewed Journal)Moraes, D.C., Baker, A.L., Wang, X., Zhu, Z., Berg, E., Trevisan, G., Zhang, J., Jayaraman, S., Linhares, D., Gauger, P.C., Silva, G.S. 2023. Veterinarian perceptions and practices in prevention and control of influenza virus in the midwest United States swine farms. Frontiers in Veterinary Infectious Diseases. 10. https://doi.org/10.3389/fvets.2023.1089132.Divergent pathology between highly pathogenic avian influenza A (H5N1) strains in swine

- (Proceedings)Arruda, B.L., Devries, A.C., Killian, M., Hines Bergeson, N., Torachetti, M., Baker, A.L. 2023. Divergent pathology between highly pathogenic avian influenza A (H5N1) strains in swine. American Association of Swine Veterinarians Annual Meeting. American Association of Swine Veterinarians Annual Meeting, March 4-7, 2023, Aurora, Colorado.smot: a python package and CLI tool for contextual phylogenetic subsampling
                                                        

- (Peer Reviewed Journal)Arendsee, Z.W., Baker, A.L., Anderson, T.K. 2022. smot: a python package and CLI tool for contextual phylogenetic subsampling. Journal of Open Source Software. 7(80). Article 4193. https://doi.org/10.21105/joss.04193.Swine influenza A viruses and pandemic preparedness

- (Peer Reviewed Journal)Anderson, T.K., Baker, A.L. 2022. Swine influenza A viruses and pandemic preparedness. Council for Agricultural Science and Technology Issue Paper. SP33:26-28.Interspecies transmission from pigs to ferrets of antigenically distinct swine H1 Influenza A viruses with reduced reactivity to candidate vaccine virus antisera as measures of relative zoonotic risk
                                                        

- (Peer Reviewed Journal)Kimble, J., Souza, C.K., Anderson, T.K., Arendsee, Z.W., Hufnagel, D.E., Young, K.M., Lewis, N.S., Davis, C., Thor, S., Baker, A.L. 2022. Interspecies transmission from pigs to ferrets of antigenically distinct swine H1 Influenza A viruses with reduced reactivity to candidate vaccine virus antisera as measures of relative zoonotic risk. Viruses. 14(11). Article 2398. https://doi.org/10.3390/v14112398.Antigenic characterization and pandemic risk assessment of North American H1 influenza A viruses circulating in swine
                                                        

- (Peer Reviewed Journal)Venkatesh, D., Anderson, T.K., Chang, J., Lopes, S., Kimble, B., Souza, C.K., Pekosz, A., Rothman, R.E., Chen, K., Baker, A.L., Lewis, N.S. 2022. Antigenic characterization and pandemic risk assessment of North American H1 influenza A viruses circulating in swine. Microbiology Spectrum. 10(6). Article e01781-22. https://doi.org/10.1128/spectrum.01781-22.Transmission of human influenza A virus in pigs selects for adaptive mutations on the HA gene
                                                        

- (Peer Reviewed Journal)Mo, J., Abente, E.J., Sutton, T.C., Ferreri, L.M., Geiger, G., Gauger, P.C., Perez, D.R., Baker, A.L., Rajao, D.S. 2022. Transmission of human influenza A virus in pigs selects for adaptive mutations on the HA gene. Journal of Virology. 96(22). Article e01480-22. https://doi.org/10.1128/jvi.01480-22.Changes in the hemagglutinin and internal gene segments were needed for human seasonal H3 influenza A virus to efficiently infect and replicate in swine
                                                        

- (Peer Reviewed Journal)Rajao, D., Abente, E.J., Powell, J.D., Bolton, M.J., Gauger, P.C., Arruda, B.L., Anderson, T.K., Sutton, T., Perez, D.R., Baker, A.L. 2022. Changes in the hemagglutinin and internal gene segments were needed for human seasonal H3 influenza A virus to efficiently infect and replicate in swine. Pathogens. 11(9). Article 967. https://doi.org/10.3390/pathogens11090967.Bivalent hemagglutinin and neuraminidase influenza replicon particle vaccines protect pigs against influenza a virus without causing vaccine associated enhanced respiratory disease
                                                        

- (Peer Reviewed Journal)Wymore Brand, M., Anderson, T.K., Kitikoon, P., Kimble, B.J., Otis, N.J., Gauger, P.C., Souza, C.K., Kaplan, B.S., Mogler, M., Strait, E., Baker, A.L. 2022. Bivalent hemagglutinin and neuraminidase influenza replicon particle vaccines protect pigs against influenza a virus without causing vaccine associated enhanced respiratory disease. Vaccine. 40(38): 5569-5578. https://doi.org/10.1016/j.vaccine.2022.07.042.Characterizing a century of genetic and antigenic diversity of N1 neuraminidase in influenza A virus from North American swine

- (Abstract Only)David, H.E., Young, K.M., Arendsee, Z.W., Gay, C.L., Caceres, J.C., Rajao, D.S., Perez, D.R., Baker, A.L., Anderson, T.K. 2022. Characterizing a century of genetic and antigenic diversity of N1 neuraminidase in influenza A virus from North American swine (abstract). Centers of Excellence for Influenza Research and Response (CEIRR) annual meeting. p. 144.Machine learning for sequence classification and predicting antigenic phenotype

- (Abstract Only)Anderson, T.K., Baker, A.L. 2022. Machine learning for sequence classification and predicting antigenic phenotype (abstract). The 65th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. p.6.Use of the ISU FLUture multisequence identity tool for rapid interpretation of swine influenza A virus sequences in the United States
                                                        

- (Peer Reviewed Journal)Zeller, M.A., Saxena, A., Anderson, T.K., Baker, A.L., Gauger, P.C. 2022. Use of the ISU FLUture multisequence identity tool for rapid interpretation of swine influenza A virus sequences in the United States. Journal of Veterinary Diagnostic Investigation. 34(5):874-878. https://doi.org/10.1177/10406387221111128.OFFLU Swine Influenza Report: July 2021 to December 2021

- (Government Publication)Markin, A., Hufnagel, D.E., Arendsee, Z., Snyder, C., Janas-Martindale, A., Inderski, B., Brown, I., Anderson, T.K., Lewis, N.S., Baker, A.L., Coggon, A., Sara, L., James, J., Mollet, B., Lewis, T. 2022. OFFLU Swine Influenza Report: July 2021 to December 2021. Technical report generated for the World Health Organization (WHO) Vaccine Consultation Meeting. p.62.Genetic and antigenic characterization of an expanding H3 influenza A virus clade in US swine visualized by Nextstrain
                                                        

- (Peer Reviewed Journal)Neveau, M.M., Zeller, M.A., Kaplan, B.S., Souza, C.K., Gauger, P.C., Baker, A.L., Anderson, T.K. 2022. Genetic and antigenic characterization of an expanding H3 influenza A virus clade in US swine visualized by Nextstrain. mSphere. 7(3). Article 00994-21. https://doi.org/10.1128/msphere.00994-21.Overview of recent USDA surveillance data

- (Proceedings)Vaccine-associated enhanced respiratory disease following influenza virus infection in ferrets recapitulates the model in pigs
                                                        

- (Peer Reviewed Journal)Kimble, B.J., Brand, M.W., Kaplan, B.S., Coyle, E.M., Chilcote, K., Gauger, P., Khurana, S., Baker, A.L. 2022. Vaccine-associated enhanced respiratory disease following influenza virus infection in ferrets recapitulates the model in pigs. Journal of Virology. 96(5). https://doi.org/10.1128/jvi.01725-21.Characterization of a 2016-2017 human-seasonal H3 influenza A virus spillover now endemic to U.S. swine
                                                        

- (Peer Reviewed Journal)Sharma, A., Zeller, M.A., Souza, C.K., Anderson, T.K., Baker, A.L., Harmon, K., Li, G., Zhang, J., Gauger, P.C. 2022. Characterization of a 2016-2017 human-seasonal H3 influenza A virus spillover now endemic to U.S. swine. mSphere. 7(1). Article e00809-21. https://doi.org/10.1128/msphere.00809-21.octoFLUshow: an interactive tool describing spatial and temporal trends in the genetic diversity of influenza A virus in U.S. swine
                                                        

- (Rapid Release Publication)Arendsee, Z.W., Chang, J., Hufnagel, D.E., Markin, A., Baker, A.L., Anderson, T.K. 2021. octoFLUshow: an interactive tool describing spatial and temporal trends in the genetic diversity of influenza A virus in U.S. swine. Microbiology Resource Announcements. 10(50). Article e01081-21. https://doi.org/10.1128/MRA.01081-21.Genetic and antigenic characterization of an expanding H3 influenza A virus clade in US swine visualized by Nextstrain
                                                        

- (Pre-print Publication)Neveau, M.N., Zeller, M.A., Kaplan, B.S., Souza, C.K., Gauger, P.C., Baker, A.L., Anderson, T.K. 2021. Genetic and antigenic characterization of an expanding H3 influenza A virus clade in US swine visualized by Nextstrain. bioRxiv. https://doi.org/10.1101/2021.11.17.469008.Antigenic distance between North American swine and human seasonal H3N2 influenza A viruses as an indication of zoonotic risk to humans
                                                        

- (Peer Reviewed Journal)Souza, C.K., Anderson, T.K., Chang, J., Venkatesh, D., Lewis, N.S., Pekosz, A., Shaw-Saliba, K., Rothman, R.E., Chen, K., Baker, A.L. 2022. Antigenic distance between North American swine and human seasonal H3N2 influenza A viruses as an indication of zoonotic risk to humans. Journal of Virology. 96(2). Article e01374-21. https://doi.org/10.1128/JVI.01374-21.Spatial and temporal coevolution of N2 neuraminidase and H1 and H3 hemagglutinin genes of influenza A virus in US swine
                                                        

- (Peer Reviewed Journal)Zeller, M.A., Chang, J., Baker, A.L., Gauger, P.C., Anderson, T.K. 2021. Spatial and temporal coevolution of N2 neuraminidase and H1 and H3 hemagglutinin genes of influenza A virus in US swine. Virus Evolution. 7(2). Article veab090. https://doi.org/10.1093/ve/veab090.Human-to-swine transmission and subsequent evolution of H1N1 pandemic 2009 lineage influenza A viruses in US swine

- (Abstract Only)Transmission bottlenecks during adaptation of human influenza A virus to pigs

- (Abstract Only)Evolution and antigenic advancement of N2 neuraminidase of swine influenza A viruses circulating in the United States following two separate introductions from human seasonal viruses
                                                        

- (Peer Reviewed Journal)Kaplan, B.S., Anderson, T.K., Chang, J., Santos, J., Perez, D., Lewis, N., Vincent, A.L. 2021. Evolution and antigenic advancement of N2 neuraminidase of swine influenza A viruses circulating in the United States following two separate introductions from human seasonal viruses. Journal of Virology. 95(20). https://journals.asm.org/doi/10.1128/JVI.00632-21.Development of a novel Live Attenuated Influenza A Virus vaccine encoding the IgA-inducing protein
                                                        

- (Peer Reviewed Journal)Caceres, J.C., Cardenas-Garcia, S., Jain, A., Gay, C.J., Carnaccini, S., Seibert, B., Ferreri, L.M., Geiger, G., Nakajiima, R., Perez, D., Rajao, D.S., Isakova-Sivak, I., Rudenko, L., Vincent, A.L., Davies, H. 2021. Development of a novel Live Attenuated Influenza A Virus vaccine encoding the IgA-inducing protein. Vaccines. 9(7). Article 703. https://doi.org/10.3390/vaccines9070703.Antigenic distance from human vaccine strains as a measure of risk to human populations from currently circulating North American swine H1 viruses

- (Abstract Only)Venkatesh, D., Kimble, B., Kunzler-Souza, C., Anderson, T.K., Chang, J., Detmer, S., Mena, I., Garcia-Sastre, A., Lewis, N., Vincent, A.L. 2021. Antigenic distance from human vaccine strains as a measure of risk to human populations from currently circulating North American swine H1 viruses [abstract]. Applied Bioinformatics and Public Health Microbiology Conference. P. none assigned.Genetic and antigenic characterization of the expanding H3 Cluster IV-A influenza A virus clade in US swine

- (Abstract Only)Neveau, M.N., Zeller, M.A., Souza, C.K., Gauger, P.C., Vincent, A.L., Anderson, T.K. 2021. Genetic and antigenic characterization of the expanding H3 Cluster IV-A influenza A virus clade in US swine [abstract].  Iowa State University Graduate and Professional Student Conference. P. none assigned.Human-to-swine spillovers of H3N2 influenza A virus detected in United States pigs in 2018-2019

- (Abstract Only)Powell, J.D., Zeller, M.A., Gauger, P.C., Anderson, T.K., Vincent, A.L. 2021. Human-to-swine spillovers of H3N2 influenza A virus detected in United States pigs in 2018-2019 [abstract].  American Society for Virology Meeting. Talk no. W21-6.Genetic and antigenic characterization of the expanding H3 Cluster IV-A influenza A virus clade in US swine

- (Abstract Only)Neveau, M.N., Zeller, M.A., Zouza, C.K., Gauder, P.C., Vincent, A.L., Anderson, T.K. 2021. Genetic and antigenic characterization of the expanding H3 Cluster IV-A influenza A virus clade in US swine [abstract]. Annual Bioinformatics and Computational Biology Symposium. P. none assigned.OFFLU Animal Influenza Report: July 2020 to December 2020

- (Government Publication)Arendsee, Z., Young, K., Hufnagel, D.E., Markin, A., Kimble, B., Kunzler-Souza, C., Brown, I., Lewis, N., Anderson, T.K., Vincent, A.L. 2021. OFFLU Animal Influenza Report: July 2020 to December 2020 [Abstract]. Technical report generated for the World Health Organization (WHO) Vaccine Consultation Meeting (VCM).Machine learning prediction and experimental validation of antigenic drift in H3 influenza A viruses in swine
                                                        

- (Peer Reviewed Journal)Zeller, M.A., Gauger, P.C., Arendsee, Z.W., Souza, C.K., Vincent, A.L., Anderson, T.K. 2021. Machine learning prediction and experimental validation of antigenic drift in H3 influenza A viruses in swine. mSphere. 6(2). https://doi.org/10.1128/mSphere.00920-20.Virus strain influenced the interspecies transmission of influenza D virus between calves and pigs
                                                        

- (Peer Reviewed Journal)Kaplan, B.S., Falkenberg, S.M., Dassanayake, R.P., Neill, J.D., Velayudhan, B., Li, F., Vincent, A.L. 2020. Virus strain influenced the interspecies transmission of influenza D virus between calves and pigs. Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.13943.Characterization of contemporary 2010.1 H3N2 swine influenza A viruses circulating in United States pigs
                                                        

- (Peer Reviewed Journal)Powell, J.D., Abente, E.J., Chang, J., Souza, C.K., Rajao, D.S., Anderson, T.K., Zeller, M.A., Gauger, P.C., Lewis, N.S., Vincent, A.L. 2021. Characterization of contemporary 2010.1 H3N2 swine influenza A viruses circulating in United States pigs. Virology. 553:94-101. https://doi.org/10.1016/j.virol.2020.11.006.N1 neuraminidase evolution and reassortment of influenza A virus in US swine

- (Abstract Only)Hufnagel, D.E., Arendsee, Z.W., Vincent, A.L., Anderson, T.K. 2020. N1 neuraminidase evolution and reassortment of influenza A virus in US swine [abstract]. Centers of Excellence for Influenza Research and Surveillance Annual Network Meeting. Poster No. 109.Increased H3 Cluster IV-A influenza A virus detection in US swine is associated with reassortment and antigenic drift

- (Abstract Only)Neveau, M.N., Zeller, M.A., Gauger, P.C., Vincent, A.L., Anderson, T.K. 2021. Increased H3 Cluster IV-A influenza A virus detection in US swine is associated with reassortment and antigenic drift [abstract]. Centers of Excellence for Influenza Research and Surveillance Annual Network Meeting. Poster No. 114.Visualizing spatial and temporal trends in influenza A virus in US swine with octoFLUshow

- (Abstract Only)Arendsee, Z.W., Chang, J., Hufnagel, D.E., Anderson, T.K., Vincent, A.L. 2021. Visualizing spatial and temporal trends in influenza A virus in US swine with octoFLUshow[abstract]. 2021 Centers of Excellence for Influenza Research and Surveillance Annual Network Meeting. Poster No. 101.Cross-reactivity of contemporary US swine H1NX viruses to current seasonal and candidate vaccine viruses as a measure of risk to humans

- (Abstract Only)Kimble, B.J., Souza, C.K., Anderson, T.K., Hufnagel, D.E., Arendsee, Z.W., Young, K.M., Lewis, N.S., Davis, T.C., Vincent, A.L. 2021. Cross-reactivity of contemporary US swine H1NX viruses to current seasonal and candidate vaccine viruses as a measure of risk to humans. Centers of Excellence for Influenza Research and Surveillance Annual Network Meeting [abstract]. Poster No. 74.Antigenic characterization of contemporary US swine H3N2 strains and transmission from swine to ferrets as an indication of risk to humans

- (Abstract Only)Souza, K, C., Kimble, B.J., Anderson, T.K., Arendsee, Z.W., Hufnagel, D.E., Young, K.M., Lewis, N.S., Davis, T.C., Vincent, A.L. 2021. Antigenic characterization of contemporary US swine H3N2 strains and transmission from swine to ferrets as an indication of risk to humans [Abstract]. 2021 Centers of Excellence for Influenza Research and Surveillance Annual Network Meeting. Poster no. 76.Detection and characterization of swine-origin Influenza A(H1N1) pandemic 2009 viruses in humans following zoonotic transmission
                                                        

- (Peer Reviewed Journal)Cook, P.W., Stark, T., Jones, J., Kondor, R., Zanders, N., Benfer, J., Scott, S., Jang, Y., Janas-Martindale, A., Lindstrom, S., Blanton, L., Schiltz, J., Tell, R., Griesser, R., Shult, P., Reisdorf, E., Danz, T., Fry, A., Barnes, J., Vincent, A.L., Wentworth, D.E., Davis, T. 2020. Detection and characterization of swine-origin Influenza A(H1N1) pandemic 2009 viruses in humans following zoonotic transmission. Journal of Virology. 95(2). https://doi.org/10.1128/JVI.01066-20.OFFLU animal influenza report: February 2020 to September 2020

- (Government Publication)Anderson, T.K., Arendsee, Z.W., Hufnagel, D., Young, K., Souza, C.K., Kimble, B., Brown, I., Essen, S., Lewis, N., Vincent, A.L., Collins, S., Byrne, A., Patapiou, P. 2020. OFFLU animal influenza report: February 2020 to September 2020. World Health Organization. p. 58.Detection of H1 Swine Influenza A Virus in Human Serum Samples by  Age Group
                                                        

- (Peer Reviewed Journal)Vandoorn, E., Leroux-Roels, I., Leroux-Roels, G., Parys, A., Vincent, A.L., Van Reeth, K. 2020. Detection of H1 Swine Influenza A Virus in Human Serum Samples by  Age Group. Emerging Infectious Diseases. 26(9):2118-2128. https://doi.org/10.3201/eid2609.191796.Aerosol transmission from infected swine to ferrets of a swine H3N2 virus collected from an agricultural fair and associated with human variant infections
                                                        

- (Peer Reviewed Journal)Kaplan, B.S., Kimble, J.B., Chang, J., Anderson, T.K., Gauger, P., Janas-Martindale, A., Killian, M., Bowman, A.S., Vincent, A.L. 2020. Aerosol transmission from infected swine to ferrets of a swine H3N2 virus collected from an agricultural fair and associated with human variant infections. Journal of Virology. https://doi.org//10.1128/JVI.01009-20.Influenza A virus field surveillance at a swine-human interface
                                                        

- (Peer Reviewed Journal)Rambo-Martin, B.L., Keller, M.W., Wilson, M.M., Nolting, J.M., Anderson, T.K., Vincent, A.L., Bagal, U., Jang, Y., Neuhaus, E.B., Davis, C.T., Bowman, A.A., Wentworth, D.E., Barnes, J.R. 2020. Influenza A virus field surveillance at a swine-human interface. mSphere. 5(1):e00822-19. https://doi.org/10.1128/mSphere.00822-19.OFFLU Animal Influenza Report: September 2019 to February 2020

- (Government Publication)Anderson, T.K., Arendsee, Z., Chang, J., Kimble, B., Kunzler-Souza, C., Brown, I., Essen, S., Collins, S., Lewis, N., Vincent, A.L., Venkatesh, D. 2020. OFFLU Animal Influenza Report: September 2019 to February 2020. World Health Organization. p. 1-60.Detection and titration of Influenza A virus neuraminidase inhibiting (NAI) antibodies using an enzyme-linked lectin assay (ELLA)

- (Book / Chapter)Serum virus neutralization assay for detection and quantitation of serum neutralizing antibodies to influenza A virus in swine

- (Book / Chapter)Diagnostic detection of live attenuated influenza virus vaccine virus and evidence of reassortment in United States swine
                                                        

- (Peer Reviewed Journal)Sharma, A., Zeller, M.A., Li, G., Harmon, K., Zhang, J., Hoang, H., Anderson, T.K., Vincent, A.L., Gauger, P.C. 2020. Detection of live attenuated influenza vaccine virus and evidence of reassortment in U.S. swine population. Journal of Veterinary Diagnostic Investigation. 32(2):301-311. https://doi.org/10.1177/1040638720907918.Swine influenza A viruses and the tangled relationship with humans
                                                        

- (Book / Chapter)Anderson, T.K., Chang, J., Arendsee, Z., Vekatesh, D., Souza, C.K., Kimble, B., Lewis, N., Davis, C., Vincent, A.L. 2020. Swine influenza A viruses and the tangled relationship with humans. In:Neumann, G. , Kawaoka, Y., editors. Influenza: The Cutting Edge. Cold Spring Harbor Perspectives in Medicine. Cold Spring Harbor Laboratory Press.10(7):p.a038737. https://doi.org/10.1101/cshperspect.a038737.Ten years after the 2009 H1N1 pandemic – what have we learned about the swine-human interface of influenza?

- (Abstract Only)Vincent, A.L., Anderson, T.K., Chang, J., Arendsee, Z.W., Venkatesh, D., Souza, C.K., Kimble, B.J., Lewis, N.S., Davis, T. 2019. Ten years after the 2009 H1N1 pandemic – what have we learned about the swine-human interface of influenza? [abstract]. The 100th Annual Conference of Research Workers in Animal Diseases (CRWAD),2019t. Abstract No. 103.OFFLU animal influenza report: February 2019-September 2019

- (Government Publication)Anderson, T.K., Arendsee, Z., Chang, J., Kimble, B., Kunzler-Souza, C., Brown, I., Essen, S., Colins, S., Lewis, N., Vincent, A.L., Venkatesh, D. 2019. OFFLU animal influenza report: February 2019-September 2019. World Health Organization. p. 1-7.Characterization of a novel human seasonal H3 influenza A virus spillover endemic in US swine

- (Abstract Only)Sharma, A., Zeller, M.A., Anderson, T.K., Vincent, A.L., Harmon, K., Li, G., Zhang, J., Gauger, P.C. 2019. Characterization of a novel human seasonal H3 influenza A virus spillover endemic in US swine [abstract]. Conference of Research Workers in Animal Diseases . Abstract No. P178.Evolutionary diversification of clade 1A.3.3.3 H1 swine influenza A viruses and zoonotic risk in the United States

- (Abstract Only)Anderson, T.K., Hewitt, K.F., Chang, J., Zeller, M.A., Venkatesh, D., Lewis, N.S., Vincent, A.L. 2019. Evolutionary diversification of clade 1A.3.3.3 H1 swine influenza A viruses and zoonotic risk in the United States [abstract]. Conference of Research Workers in Animal Diseases. Abstract No. 181.OctoFlu: Automated classification of influenza A virus gene sequences detected in U.S. swine to evolutionary origin
                                                        

- (Peer Reviewed Journal)Chang, J., Anderson, T.K., Zeller, M.A., Gauger, P.C., Vincent, A.L. 2019. OctoFlu: Automated classification of influenza A virus gene sequences detected in U.S. swine to evolutionary origin. Microbiology Resource Announcements. 8(32):e00673-19. https://doi.org/10.1128/MRA.00673-19.An automated annotation tool and unified nomenclature system for H3 hemagglutinin genes from swine influenza A viruses

- (Abstract Only)A serosurvey for bovine Influenza D virus exposure from cattle in the United States, 2014-2015
                                                        

- (Peer Reviewed Journal)Silveira, S., Falkenberg, S.M., Kaplan, B.S., Crossley, B., Ridpath, J.F., Bauermann, F.B., Fossler, C.P., Dargatz, D.A., Dassanayake, R.P., Vincent, A.L., Canal, C.W., Neill, J.D. 2019. Serosurvey for influenza D virus exposure in cattle, United States, 2014-2015. Emerging Infectious Diseases. 25(11). https://doi.org/10.3201/eid2511.1902532.Mitigating pandemic risk with influenza A virus field surveillance: mia (mobile influenza analysis)

- (Abstract Only)Barnes, J.R., Rambo-Martin, B.L., Keller, M.W., Wilson, M.M., Nolting, J.M., Anderson, T.K., Bagal, U., Jang, Y., Davis, C.T., Bowman, A.A., Wentworth, D.E., Vincent, A.L. 2019. Mitigating pandemic risk with influenza A virus field surveillance: mia (mobile influenza analysis) [abstract]. Options for the Control of Influenza Conference. Abstract No. 10960.Characterization of a novel human seasonal H3 influenza A virus spillover that is now endemic in US swine

- (Abstract Only)Sharma, A., Zeller, M., Anderson, T.K., Vincent, A.L., Harmon, K., Li, G., Zhang, J., Gauger, P.C. 2019. Characterization of a novel human seasonal H3 influenza A virus spillover that is now endemic in US swine [abstract]. American Association of Veterinary Laboratory Diagnosticians Annual Meeting. p. 13.Spatial and temporal patterns of swine IAV gene constellations and reassortment in the USA from 2009 to 2019

- (Abstract Only)Chang, J., Anderson, T.K., Vincent, A.L. 2019. Spatial and temporal patterns of swine IAV gene constellations and reassortment in the USA from 2009 to 2019 [abstract] . CEIRS Network Meeting. p. none assigned.Vaccine-associated enhanced respiratory disease in swine and ferrets

- (Abstract Only)Kimble, J.B., Brand, M.W., Kaplan, B.S., Zoul, J., Vincent, A.L. 2019. Vaccine-associated enhanced respiratory disease in swine and ferrets [abstract]. p. none assigned.Vaccine-associated enhanced respiratory disease in swine and ferrets

- (Abstract Only)Kimble, J.B., Brand, M.W., Kaplan, B.S., Zoul, J., Vincent, A.L. 2019. Vaccine-associated enhanced respiratory disease in swine and ferrets [abstract]. CEIRS Annual meeting. p. none assigned.Antigenic differences between the two N2 neuraminidase lineages of North American swine influenza A viruses

- (Abstract Only)Kaplan, B.S., Anderson, T.K., Santos, J., Perez, D., Lewis, N., Vincent, A.L. 2019. Antigenic differences between the two N2 neuraminidase lineages of North American swine influenza A viruses [abstract]. p. none assigned.Antigenic differences between the two N2 neuraminidase lineages of North American swine influenza A viruses

- (Abstract Only)Kaplan, B.S., Anderson, T.K., Santos, J., Perez, D., Lewis, N., Vincent, A.L. 2019. Antigenic differences between the two N2 neuraminidase lineages of North American swine influenza A viruses [abstract]. CEIRS Network Meeting.  p. none assigned.An automated annotation tool and unified nomenclature system for H3 hemagglutinin genes from swine influenza A viruses

- (Abstract Only)Anderson, T.K., Zhang, Y., Macken, C.A., Swine Flu Work Group, Scheuermann, R.H., Vincent, A.L. 1019. An automated annotation tool and unified nomenclature system for H3 hemagglutinin genes from swine influenza A viruses [abstract].  Centers of Excellence for Influenza Research and Surveillance. Abstract No. 42.Molecular determinants facilitating sustained interspecies transmission of human H3N2 influenza A virus in United States pigs

- (Abstract Only)Powell, J.D., Abente, E.J., Souza, C.K., Chang, J., Rajao, D.S., Anderson, T.K., Vincent, A.L. 2019. Molecular determinants facilitating sustained interspecies transmission of human H3N2 influenza A virus in United States pigs [abstract]. Centers of Excellence Influenza Research and Surveillance (CEIRS) meeting. p. none assigned.Antigenic distance of North American swine influenza A virus (H3N2) and human seasonal vaccine strains as an indication of risk to human populations

- (Abstract Only)Souza, C.K., Venkatesh, D., Anderson, T.K., Chang, J., Lewis, N.S., Detmer, S.E., Mena, I., Culhane, M., Nelson, M., Garcia-Sastre, A., Vincent, A.L. 2019. Antigenic distance of North American swine influenza A virus (H3N2) and human seasonal vaccine strains as an indication of risk to human populations. CEIRS Annual Network Meeting [abstract].  p. none assigned.A brief introduction to influenza A virus in swine
                                                        

- (Book / Chapter)Vincent, A.L., Anderson, T.K., Lager, K.M. 2020. A brief introduction to influenza A virus in swine. Animal Influenza Virus. p. 249-271. https://doi.org/10.1007/978-1-0716-0346-8_18.Evolution of influenza A virus in swine and vaccine selection

- (Proceedings)Vincent, A.L., Anderson, T.K., Chang, J. 2019. Evolution of influenza A virus in swine and vaccine selection. In: Proceedings of the Iowa Veterinary Medical Association, February 13-14, 2019, Altoona, Iowa. none.Swine influenza A viruses: quantifying genetic diversity with phylogenetics and the octoFLU pipeline

- (Proceedings)Anderson, T.K., Chang, J., Arendsee, Z.W., Vincent, A.L. 2020. Swine influenza A viruses: quantifying genetic diversity with phylogenetics and the octoFLU pipeline. Proceedings of American Association of Swine Veterinarians Annual Meeting. Seminar No. 9.Adaptation of human influenza viruses to swine
                                                        

- (Review Article)Rajao, D.S., Vincent, A.L., Perez, D.R. 2019. Adaptation of human influenza viruses to swine. Frontiers in Veterinary Science. 5:347. https://doi.org/10.3389/fvets.2018.00347.An avian influenza virus A (H7N9) reassortant that recently emerged in the United States with low and highly pathogenic phenotype does not efficiently infect swine
                                                        

- (Peer Reviewed Journal)Powell, J.D., Abente, E.J., Torchetti, M.K., Killian, M.L., Vincent, A.L. 2019. An avian influenza virus A (H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine. Influenza and Other Respiratory Viruses. 13:288-291. https//doi.org/10.1111/irv.12631.Alphavirus-vectored HA subunit vaccine provides partial protection against heterologous challenge in pigs
                                                        

- (Peer Reviewed Journal)Abente, E.J., Rajao, D.S., Gauger, P.C., Vincent, A.L. 2019. Alphavirus-vectored hemagglutinin subunit vaccine provides partial protection against heterologous challenge in pigs. Vaccine. 37(11):1533-1539. https://doi.org/10.1016/j.vaccine.2018.12.071.Respiratory immunology – a flu focus

- (Proceedings)Vincent, A.L., Wymore-Brand, M. 2019. Respiratory immunology – a flu focus. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 9-12, Orlando, Florida. Not available.Complete genome sequences of two novel human-like H3N2 influenza A viruses A/swine/Oklahoma/65980/2017(H3N2) and A/swine/Oklahoma/65260/2017(H3N2) detected in swine in the United States
                                                        

- (Peer Reviewed Journal)Zeller, M.A., Li, G., Harmon, K.M., Zhang, J., Vincent, A.L., Anderson, T.K., Gauger, P.C. 2018. Complete genome sequences of two novel human-like H3N2 influenza A viruses A/swine/Oklahoma/65980/2017(H3N2) and A/swine/Oklahoma/65260/2017(H3N2) detected in swine in the United States. Microbiology Resource Announcements. 7(20):e01203-18. https://doi.org/10.1128/MRA.01203-18.N2 NA and HA coordinated evolution increases influenza A virus genetic diversity in swine

- (Abstract Only)Zeller, M.A., Anderson, T.K., Vincent, A.L., Gauger, P.C. 2018. N2 NA and HA coordinated evolution increases influenza A virus genetic diversity in swine [abstract]. Research Workers in Animal Diseases Conference Proceedings. p. none assigned.Spatial and temporal patterns of swine IAV gene constellations in the USA from 2010 to 2018

- (Abstract Only)Chang, J., Anderson, T.K., Vincent, A.L. 2018. Spatial and temporal patterns of swine IAV gene constellations in the USA from 2010 to 2018 [abstract]. Research Workers in Animal Diseases Conference Proceedings. p. none assigned.Plasticity of amino acid residue 145 near the receptor binding site (RBS) of H3 influenza A viruses and its impact on receptor binding and antibody recognition
                                                        

- (Peer Reviewed Journal)Santos, J., Abente, E.J., Obadan, A.O., Thompson, A.J., Ferreri, L., Geiger, G., Gonzalez-Reiche, A.S., Lewis, N.S., Burke, D., Rajão, D.S., Paulson, J.C., Vincent, A.L., Perez, D.R. 2018. Plasticity of amino acid residue 145 near the receptor binding site of H3 swine influenza A viruses and its impact on receptor binding and antibody recognition. Journal of Virology. 93(2):e01413-18. https://doi.org/10.1128/JVI.01413-18.Genetic diversity of influenza A viruses in swine in southeast Mexico
                                                        

- (Peer Reviewed Journal)Nelson, M.I., Souza, C., Trovão, N.S., Diaz, A., Mena, I., Rovira, A., Vincent, A.L., Torremorell, M., Marthaler, D., Culhane, M.R. 2019. Human-origin influenza A (H3N2) reassortant viruses in swine, southeast Mexico. Emerging Infectious Diseases. 25(4):691-700. https://doi.org/10.3201/eid2504.180779.ISU FLUture: a veterinary diagnostic laboratory web-based platform to monitor the temporal genetic patterns of influenza A virus in swine
                                                        

- (Peer Reviewed Journal)Zeller, M.A., Anderson, T.K., Walia, R.W., Vincent, A.L., Gauger, P.C. 2018. ISU FLUture: a veterinary diagnostic laboratory web-based platform to monitor the temporal genetic patterns of influenza A virus in swine. BMC Bioinformatics. 19:397. https://doi.org/10.1186/s12859-018-2408-7.Antigenic evolution of H3N2 influenza A viruses in swine in the United States, 2012–16
                                                        

- (Peer Reviewed Journal)Bolton, M.J., Abente, E.J., Venkatesh, D., Stratton, J.A., Zeller, M., Anderson, T.K., Lewis, N.S., Vincent, A.L. 2018. Antigenic evolution of H3N2 influenza A viruses in swine in the United States from 2012–2016. Influenza and Other Respiratory Viruses. 13:83-90. https://doi.org/10.1111/irv.12610.Influenza A (H3N2) variant virus outbreak at three fairs - Maryland, 2017
                                                        

- (Peer Reviewed Journal)Duwell, M., Blythe, D., Radebaugh, M.W., Kough, E.M., Bachaus, B., Crum, D.A., Perkins Jr., K.A., Blanton, L., Davis, T., Jang, Y., Vincent, A.L., Chang, J., Abney, D.E., Gudmundson, L., Brewster, M.G., Polsky, L., Rose, D., Feldman, K.A. 2018. Influenza A (H3N2) variant virus outbreak at three fairs - Maryland, 2017. Morbidity and Mortality Weekly Reports. 67(42):1169-1173. https://doi.org/10.15585/mmwr.mm6742a1.Comparison of adjuvanted-whole inactivated virus and live-attenuated virus vaccines against challenge with contemporary, antigenically distinct H3N2 influenza A viruses
                                                        

- (Peer Reviewed Journal)Abente, E.J., Rajao, D.S., Santos, J., Kaplan, B.S., Nicholson, T.L., Brockmeier, S.L., Gauger, P.C., Perez, D.R., Vincent, A.L. 2018. Comparison of adjuvanted-whole inactivated virus and live-attenuated virus vaccines against challenge with contemporary, antigenically distinct H3N2 influenza A viruses. Journal of Virology. 92(22):e01328-18. https://doi.org/10.1128/JVI.01323-18.The type of adjuvant in whole inactivated influenza A virus vaccines impacts vaccine-associated enhanced respiratory disease
                                                        

- (Peer Reviewed Journal)Souza, C.K., Rajão, D.S., Sandbulte, M.R., Lopes, S., Lewis, N.S., Loving, C.L., Gauger, P.C., Vincent, A.L. 2018. The type of adjuvant in whole inactivated influenza A virus vaccines impacts vaccine-associated enhanced respiratory disease. Vaccine. 36(41):6103-6110. https://doi.org/10.1016/j.vaccine.2018.08.072.Live-attenuated virus vaccine provides complete protection against antigenically distinct H3N2 influenza A viruses

- (Abstract Only)Rajao, D., Vincent, A.L., Santos, J., Kaplan, B.S., Nicholson, T.L., Brockmeier, S., Gauger, P.C., Perez, D.R., Abente, E.J. 2018. Live-attenuated virus vaccine provides complete protection against antigenically distinct H3N2 influenza A viruses [abstract]. p. none assigned.Antigenic distance of swine and human seasonal H3N2 influenza A virus strains as an indication of risk to human populations

- (Abstract Only)Souza, C.K., Anderson, T., Bolton, M., Venkatesh, D., Lewis, N., Detmer, S.E., Mena, I., Culhane, M., Nelson, M., Larsen, L., Abente, E.J., García-Sastre, A., Vincent, A.L. 2018. Antigenic distance of swine and human seasonal H3N2 influenza A virus strains as an indication of risk to human populations [abstract]. Proceedings of Allen D Leman Swine Conference. p. none assigned.Regional Patterns of Genetic Diversity in Swine Influenza A Viruses in The United States From 2010 to 2016
                                                        

- (Peer Reviewed Journal)Walia, R.R., Anderson, T.K., Vincent, A.L. 2018. Regional patterns of genetic diversity in swine influenza A viruses in the United States from 2010 to 2016. Influenza and Other Respiratory Viruses. https://doi.org/10.1111/irv.12559.Automating genetic classification for hemagglutinin and neuraminidase genes from influenza A viruses through machine learning methods

- (Abstract Only)Zeller, M., Anderson, T., Vincent, A.L., Gauger, P. 2018. Automating genetic classification for hemagglutinin and neuraminidase genes from influenza A viruses through machine learning methods [abstract]. Pig Veterinary Society International Congress Proceedings. p. none assigned.The other influenza surface glycoprotein: probing the antigenic differences between N2 neuraminidase lineages of North American swine influenza a viruses

- (Abstract Only)Kaplan, B.S., Anderson, T.K., Santos, J., Perez, D., Lewis, N., Vincent, A.L. 2018. The other influenza surface glycoprotein: probing the antigenic differences between N2 neuraminidase lineages of North American swine influenza a viruses [abstract]. International Symposium on Neglected Influenza Viruses. Abstract No. O16.An automated annotation tool and unified nomenclature system for H3 hemagglutinin genes from swine influenza A viruses

- (Abstract Only)Anderson, T.K., Zhang, Y., Macken, C.A., Offlu Swine, I., Scheuermann, R.H., Vincent, A.L. 2018. An automated annotation tool and unified nomenclature system for H3 hemagglutinin genes from swine influenza A viruses [abstract].International Symposium on Neglected Influenza Viruses. Abstract No. P2.Pathogenesis and transmission in the swine host of influenza A viruses with dominant H1 genome constellations found in U.S. swine herds

- (Abstract Only)Souza, C.K., Anderson, T.K., Kaplan, B.S., Gauger, P.C., Abente, E.J., Vincent, A.L. 2018. Pathogenesis and transmission in the swine host of influenza A viruses with dominant H1 genome constellations found in U.S. swine herds [abstract]. International Symposium on Neglected Influenza Viruses. Abstract No.O10.Antigenic distance of swine H3N2 and human seasonal strains as an indication of risk to human populations

- (Abstract Only)Souza, C.K., Anderson, T.K., Venkatesh, D., Bolton, M., Abente, E.J., Lewis, N., Vincent, A.L. 2018. Antigenic distance of swine H3N2 and human seasonal strains as an indication of risk to human populations [abstract]. International Symposium on Neglected Influenza Viruses.  Abstract No. P23.Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States
                                                        

- (Peer Reviewed Journal)Rajao, D.S., Anderson, T.K., Kitikoon, P., Stratton, J., Lewis, N.S., Vincent, A.L. 2018. Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States. Virology. 518:45-54. https://doi.10.1016/j.virol.2018.02.006.ISU FLUture: using veterinary diagnostic laboratory data to monitor the temporal genetic patterns of influenza A virus in swine

- (Proceedings)Zeller, M., Vincent, A.L., Anderson, T., Main, R., Gauger, P. 2018. ISU FLUture: using veterinary diagnostic laboratory data to monitor the temporal genetic patterns of influenza A virus in swine. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 3-6, 2018, San Diego, California. https://www.aasv.org/annmtg/.Serological evaluation of influenza A virus vaccine antibody responses in replacement gilts on twelve breeding farms in the United States

- (Proceedings)Carlson, J., Vincent, A.L., Zhang, J., Gauger, P.C. 2018. Serological evaluation of influenza A virus vaccine antibody responses in replacement gilts on twelve breeding farms in the United States. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 3-6, 2018, San Diego, California. https://www.aasv.org/annmtg/.Vaccination of pigs with a codon-pair bias de-optimized live attenuated influenza vaccine protects from homologous challenge
                                                        

- (Peer Reviewed Journal)Kaplan, B.S., Souza, C.K., Gauger, P.C., Stauft, C.B., Coleman, J.R., Mueller, S., Vincent, A.L. 2018. Vaccination of pigs with a codon-pair bias de-optimized live attenuated influenza vaccine protects from homologous challenge. Vaccine. 36(8):1101-1107. https://doi.10.1016/j.vaccine.2018.01.027.Detection and characterization of an H4N6 avian-lineage influenza A virus in pigs in the Midwestern United States
                                                        

- (Peer Reviewed Journal)Abente, E.J., Gauger, P.C., Walia, R.R., Rajao, D.S., Zhang, J., Harmon, K.M., Killian, M., Vincent, A.L. 2017. Detection and characterization of an H4N6 avian-lineage influenza A virus in pigs in the midwestern United States. Virology. 511:56-65. https://doi.org/10.1016/j.virol.2017.08.021.Influenza A (H3N2) virus in swine at agricultural fairs and transmission to humans, Michigan and Ohio, USA, 2016
                                                        

- (Peer Reviewed Journal)Bowman, A.S., Walia, R.R., Nolting, J.M., Vincent, A.L., Killian, M.L., Zentkovich, M.M., Lorbach, J.N., Lauterbach, S.E., Anderson, T.K., Davis, C.T., Zanders, N., Jones, J., Yang, Y., Lynch, B., Rodriguez, M.R., Blanton, L., Lindstrom, S.E., Wentworth, D.E., Schiltz, J., Averill, J.J., Forshey, T. 2017. Influenza A (H3N2) virus in swine at agricultural fairs and transmission to humans, Michigan and Ohio, USA, 2016. Emerging Infectious Diseases. 23(9):1551-1555. https://doi.org/10.3201/eid2309.170847.The genomic evolution of H1 influenza A viruses from swine detected in the United States between 2009 and 2016

- (Peer Reviewed Journal)Gao, S., Anderson, T.K., Walia, R.R., Dorman, K.S., Janas-Martindale, A., Vincent, A.L. 2017. The genomic evolution of H1 influenza A viruses from swine detected in the United States between 2009 and 2016. Journal of General Virology. 98(8):2001-2010.Absence of clinical disease and contact transmission of North American clade 2.3.4.4 H5NX HPAI in experimentally infected pigs

- (Peer Reviewed Journal)Kaplan, B.S., Torchetti, M.K., Lager, K.M., Webby, R.J., Vincent, A.L. 2017. Absence of clinical disease and contact transmission of HPAI H5NX clade 2.3.4.4 from North America in experimentally infected pigs. Influenza and Other Respiratory Viruses. 11(5):464-470.Factors affecting induction of peripheral IFN-gamma recall response to influenza A virus vaccination in pigs

- (Peer Reviewed Journal)Olson, Z.F., Sandbulte, M.R., Kunzler Souza, C., Perez, D.R., Vincent, A.L., Loving, C.L. 2017. Factors affecting induction of peripheral IFN-gamma recall response to influenza A virus vaccination in pigs. Veterinary Immunology and Immunopathology. 185:57-65. doi: 10.1016/j.vetimm.2017.01.009.A highly pathogenic avian influenza virus H5N1 with 2009 pandemic H1N1 internal genes demonstrated increased replication and transmission in pigs

- (Peer Reviewed Journal)Abente, E.J., Kitikoon, P., Lager, K.M., Gauger, P.C., Anderson, T.K., Vincent, A.L. 2017. A highly pathogenic avian-derived influenza virus H5N1 with 2009 pandemic H1N1 internal genes demonstrates increased replication and transmission in pigs. Journal of General Virology. 98(1):18-30.Reassortment between swine H3N2 and 2009 pandemic H1N1 in the United States resulted in influenza A viruses with diverse genetic constellations with variable virulence in pigs

- (Peer Reviewed Journal)Rajao, D.S., Walia, R.R., Campbell, B., Gauger, P.C., Janas-Martindale, A., Killian, M.L., Vincent, A.L. 2017. Reassortment between swine H3N2 and 2009 pandemic H1N1 in the United States resulted in influenza A viruses with diverse genetic constellations with variable virulence in pigs. Journal of Virology. 91:e01763-16. doi.org/10.1128/JVI.01763-16.The future of influenza A virus vaccines for swine

- (Review Article)Vincent, A.L., Perez, D.R., Rajao, D., Anderson, T.K., Abente, E.J., Walia, R.R., Lewis, N.S. 2016. Influenza A virus vaccines for swine. Veterinary Microbiology. 206:35-44.A phylogeny-based global nomenclature system and automated annotation tool for H1 hemagglutinin genes from swine influenza A viruses

- (Peer Reviewed Journal)Anderson, T.K., Macken, C.A., Lewis, N.S., Scheuermann, R.H., Van Reeth, K., Brown, I.H., Swenson, S.L., Simon, G., Saito, T., Berhane, Y., Ciacci-Zanella, J., Pereda, A., Davis, C.T., Donis, R.O., Webby, R.J., Vincent, A.L. 2016. A phylogeny-based global nomenclature system and automated annotation tool for H1 hemagglutinin genes from swine influenza A viruses. mSphere. 1(6):e00275-16. doi:10.1128/mSphere.00275-16.The B. bronchiseptica type III secretion system does not negatively affect the protective immunity induced by influenza A virus vaccines

- (Abstract Only)Nicholson, T.L., Vincent, A.L., Brockmeier, S., Rajão, D.S., Abente, E.J., Gauger, P.C. 2016. The B. bronchiseptica type III secretion system does not negatively affect the protective immunity induced by influenza A virus vaccines. Conference of Research Workers in Animals Diseases Meeting. Paper No. P139.Surveillance for highly pathogenic H5 avian influenza virus in synanthropic wildlife associated with poultry farms during an acute outbreak

- (Peer Reviewed Journal)Shriner, S.A., Root, J.J., Lutman, M.W., Kloft, J.M., VanDalen, K.K., Sullivan, H.J., White, T.S., Milleson, M.P., Hairston, J.L., Chandler, S.C., Wolf, P.C., Turnage, C.T., McCluskey, B.J., Vincent, A.L., Torchetti, M.K., Gidlewski, T., DeLiberto, T.J. 2016. Surveillance for highly pathogenic H5 avian influenza virus in synanthropic wildlife associated with poultry farms during an acute outbreak. Scientific Reports. 6:36237. doi: 10.1038/srep36237.Pigs with severe combined immunodeficiency (SCID) are impaired in controlling influenza A virus infection

- (Peer Reviewed Journal)Rajao, D.S., Loving, C.L., Waide, E.H., Gauger, P.C., Dekkers, J.C., Tuggle, C.K., Vincent, A.L. 2017. Pigs with severe combined immunodeficiency are impaired in controlling influenza virus infection. Journal of Innate Immunity. 9(2):193-202.Influenza research database: an integrated bioinformatics resource for influenza virus research

- (Peer Reviewed Journal)Zhang, Y., Aevermann, B., Anderson, T.K., Burke, D.F., Dauphin, G., Gu, Z., He, S., Kumar, S., Larsen, C.N., Lee, A.J., Li, X., Macken, C., Mahaffey, C., Pickett, B.E., Reardon, B., Smith, T., Stewart, L., Suloway, C., Sun, G., Tong, L., Vincent, A.L., Walters, B., Zaremba, S., Zhao, H., Zhou, L., Zmasek, C., Klem, E.B., Scheuermann, R.H. 2017. Influenza research database: an integrated bioinformatics resource for influenza virus research. Nucleic Acids Research. 45(D1):D466-D474. doi:10.1093/nar/gkw857.Global evolution of influenza A viruses in swine

- (Book / Chapter)The genetic diversity of contemporary swine influenza A viruses in the United States

- (Popular Publication)Walia, R.R., Anderson, T.K., Vincent, A.L. 2016. The genetic diversity of contemporary swine influenza A viruses in the United States. Available: https://www.pig333.com/swine-influenza/.The molecular determinants of antibody recognition and antigenic drift in the H3 hemagglutinin of swine influenza A virus

- (Peer Reviewed Journal)Abente, E.J., Santos, J., Lewis, N.S., Gauger, P.C., Stratton, J., Skepner, E., Anderson, T.K., Rajao, D.S., Perez, D.R., Vincent, A.L. 2016. The molecular determinants of antibody recognition and antigenic drift in the H3 hemagglutinin of swine influenza A virus. Journal of Virology. 90(18):8266-8280.Neuraminidase inhibiting antibody responses in pigs differ between influenza A virus N2 lineages and by vaccine type
                                                        

- (Peer Reviewed Journal)Sandbulte, M.R., Gauger, P.C., Kitikoon, P., Chen, H., Perez, D.P., Roth, J.A., Vincent, A.L. 2016. Neuraminidase inhibiting antibody responses in pigs differ between influenza A virus N2 lineages and by vaccine type. Vaccine. 34(33):3773-3779.The avian-origin H3N2 canine influenza virus has limited replication in swine

- (Peer Reviewed Journal)Abente, E.J., Anderson, T.K., Rajao, D.S., Swenson, S., Gauger, P.C., Vincent, A.L. 2016. The avian-origin H3N2 canine influenza virus that recently emerged in the United States has limited replication in swine. Influenza and Other Respiratory Viruses. 10(5):429-432.Vaccine-associated enhanced respiratory disease is influenced by hemagglutinin and neuraminidase in whole inactivated influenza virus vaccines

- (Peer Reviewed Journal)Rajão, D.S., Chen, H., Perez, D.R., Sandbulte, M.R., Gauger, P.C., Loving, C.L., Shanks, G., Vincent, A.L. 2016. Vaccine-associated enhanced respiratory disease is influenced by hemagglutinin and neuraminidase in whole inactivated influenza virus vaccines. Journal of General Virology. 97(7):1489-1499.Age at vaccination and timing of infection do not alter vaccine-associated enhanced respiratory disease in influenza A virus infected pigs

- (Peer Reviewed Journal)Souza, C.K., Rajão, D.S., Loving, C.L., Gauger, P.C., Pérez, D.R., Vincent, A.L. 2016. Age at vaccination and timing of infection do not alter vaccine-associated enhanced respiratory disease in influenza A virus infected pigs. Clinical and Vaccine Immunology. 23:470–482.Quantifying the global antigenic diversity of swine influenza A viruses

- (Peer Reviewed Journal)Lewis, N.S., Russell, C.A., Langat, P., Anderson, T.K., Berger, K., Bielejec, F., Burke, D.F., Dudas, G., Fonville, J.M., Fouchier, R.A., Kellam, P., Koel, B.F., Lemey, P., Nguyen, T., Nuansrichy, B., Peiris, J.M., Saito, T., Simon, G., Skepner, E., Takemae, N., ESNIP3 consortium, Webby, R.J., van Reeth, K., Brookes, S.M., Larsen, L., Watson, S.J., Brown, I.H., Vincent, A.L. 2016. The global antigenic diversity of swine influenza A viruses. eLife. 5:e12217.The B. bronchiseptica type III secretion system does not negatively affect the protective immunity induced by influenza A virus vaccines

- (Abstract Only)Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses
                                                        

- (Peer Reviewed Journal)Balzli, C., Lager, K., Vincent, A., Gauger, P., Brockmeier, S., Miller, L., Richt, J.A., Ma, W., Suarez, D., Swayne, D.E. 2016. Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses. Influenza and Other Respiratory Viruses. 10(4):346-352.Current trends from the USDA influenza a virus in swine surveillance system

- (Abstract Only)Reassortment between swine H3N2 and 2009 pandemic H1N1 generated diverse genetic constellations in influenza A viruses currently circulating in pigs in the United States

- (Abstract Only)Pathogenesis and transmission of highly pathogenic avian influenza H5Nx in swine

- (Abstract Only)Vaccine efficacy of live-attenuated virus, whole inactivated virus and alphavirus vectored subunit vaccines against antigenically distinct H3N2 swine influenza A viruses

- (Abstract Only)Genetic evolution of recently emerged novel human-like swine H3 influenza A viruses (IAV) in United States swine

- (Abstract Only)Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets

- (Peer Reviewed Journal)Rajao, D.S., Sandbulte, M.R., Gauger, P.C., Kitikoon, P., Platt, R., Roth, J.A., Perez, D.R., Loving, C.L., Vincent, A.L. 2016. Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets. Virology. 491:79-88.Pathogenesis and transmission studies: non-swine influenza A viruses in the swine host

- (Proceedings)Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States

- (Peer Reviewed Journal)Rajao, D.S., Gauger, P.C., Anderson, T.K., Lewis, N.S., Abente, E.J., Killian, M.L., Perez, D.R., Sutton, T.C., Zhang, J., Vincent, A.L. 2015. Novel reassortant human-like H3N2 and H3N1 influenza A viruses detected in pigs are virulent and antigenically distinct from swine viruses endemic to the United States. Journal of Virology. 89(22):11213-11222.Oral fluids as a live-animal sample for evaluating cross-reactivity and cross-protection following intranasal influenza A virus vaccination in pigs

- (Peer Reviewed Journal)Hughes, H.R., Vincent, A.L., Brockmeier, S.L., Gauger, P.C., Pena, L., Santos, J., Braucher, D.R., Perez, D.R., Loving, C.L. 2015. Oral fluids as a live-animal sample source for evaluating cross-reactivity and cross-protection following intranasal influenza A virus vaccination in pigs. Clinical and Vaccine Immunology. 22(10):1109-1120.Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time, reverse transcription polymerase chain reaction (rRT-PCR) and virus isolation

- (Peer Reviewed Journal)Goodell, C.K., Zhang, J., Strait, E., Harmon, K., Patnayak, D., Otterson, T., Culhane, M., Christopher-Hennings, J., Clement, T., Leslie-Steen, P., Hesse, R., Anderson, J., Skarbek, K., Vincent, A., Kitikoon, P., Swenson, S., Jenkins-Moore, M., McGill, J., Rauh, R., Nelson, W., O'Connell, C., Shah, R., Wang, C., Main, R., Zimmerman, J.J. 2016. Ring test evaluation of the detection of influenza A virus in swine oral fluids by real-time reverse-transcription polymerase chain reaction and virus isolation. Canadian Journal of Veterinary Research. 80(1):12-20.Replication and transmission of mammalian-adapted H9 subtype influenza virus in pigs and quail

- (Peer Reviewed Journal)Obadan, A.O., Kimble, B.J., Rajao, D., Lager, K.M., Santos, J.J., Vincent, A.L., Perez, D.R. 2015. Replication and transmission of mammalian-adapted H9 subtype influenza virus in pigs and quail. Journal of General Virology. 96:2511-2521.Continual re-introduction of human pandemic H1N1 influenza A viruses into US swine, 2009-2014

- (Peer Reviewed Journal)Nelson, M.I., Stratton, J., Killian, M.L, Janas-Martindale, A., Vincent, A.L. 2015. Continual reintroduction of human pandemic H1N1 influenza A viruses into swine in the United States, 2009-2014. Journal of Virology. 89(12):6218-6226.Immune mechanisms associated with enhanced influenza A virus disease versus cross-protection in vaccinated pigs.

- (Abstract Only)A TaqMan-based real-time PCR assay for porcine parvovirus 4 detection and quantification in reproductive tissues of sows

- (Peer Reviewed Journal)Gava, D., Souza, C.K., Schaefer, R., Vincent, A.L., Cantão, M.E., Coldebella, A., Ciacci-Zanella, J.R. 2015. A TaqMan-based real-time PCR for detection and quantification of porcine parvovirus 4. Journal of Virological Methods. 219:14–17.Global migration of influenza A viruses in swine

- (Peer Reviewed Journal)Nelson, M.I., Viboud, C., Vincent, A.L., Culhane, M.R., Detmer, S.E., Wentworth, D.E., Rambaut, A., Suchard, M.A., Holmes, E.C., Lemey, P. 2015. Global migration of influenza A viruses in swine. Nature Communications. 6:6696.Characterization of co-circulating swine influenza A viruses in North America and the identification of a novel H1 genetic clade with antigenic significance

- (Peer Reviewed Journal)Anderson, T.K., Campbell, B.A., Nelson, M.I., Lewis, N.S., Janas-Martindale, A., Killian, M., Vincent, A.L. 2015. Characterization of co-circulating swine influenza A viruses in North America and the identification of a novel H1 genetic clade with antigenic significance. Virus Research. 201:24–31.Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface

- (Review Article)Nelson, M.I., Vincent, A.L. 2015. Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface. Trends in Microbiology. 23(3):142-153.Comparative virulence of wild-type H1N1pdm09 influenza A isolates in swine

- (Peer Reviewed Journal)Henningson, J.N., Rajao, D.S., Kitikoon, P., Lorusso, A., Culhane, M.R., Lewis, N.S., Anderson, T.K., Vincent, A.L. 2015. Comparative virulence of wild-type H1N1pdm09 influenza A isolates in swine. Veterinary Microbiology. 176(1-2):40-49.Swine as a model for influenza A virus infection

- (Book / Chapter)Rajao, D.S., Vincent, A.L. 2015. Swine as a model for influenza A virus infection and immunity. ILAR Journal. 56(1):44-52.Lymphocyte responses in the lungs of vaccinated pigs following homologous and heterologous influenza A virus challenge.

- (Abstract Only)Mucosal correlates of cross-protection for live-attenuated influenza virus vaccines in pigs.

- (Abstract Only)Live attenuated influenza A virus vaccine protects against heterologous challenge with A(H1N1)pdm09 without inducing vaccine associated enhanced respiratory disease

- (Peer Reviewed Journal)Gauger, P.C., Loving, C.L., Khurana, S., Lorusso, A., Perez, D.R., Kehrli, Jr., M.E., Roth, J.A., Golding, H., Vincent, A.L. 2014. Live attenuated influenza A virus vaccine protects against A(H1N1)pdm09 heterologous challenge without vaccine associated enhanced respiratory disease. Virology. 471-473:93-104.Polymorphisms in the hemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine

- (Peer Reviewed Journal)Lorusso, A., Ciacci-Zanella, J.R., Zanella, E.L., Pena, L., Perez, D.R., Lager, K.M., Rajao, D.S., Loving, C.L., Kitikoon, P., Vincent, A.L. 2014. Polymorphisms in the hemagglutinin gene influenced the viral shedding of pandemic 2009 influenza virus in swine. Journal of General Virology. 95(Pt 12):2618-2626.Influenza A virus hemagglutinin protein subunit vaccine elicits vaccine-associated enhanced respiratory disease

- (Peer Reviewed Journal)Rajão, D.S., Loving, C.L., Gauger, P.C., Kitikoon, P., Vincent, A.L. 2014. Influenza A virus hemagglutinin protein subunit vaccine elicits vaccine-associated enhanced respiratory disease. Vaccine. 32(40):5170-5176.Issues encountered in development of enzyme-linked immunosorbent assay for use in detecting influenza A virus subtype H5N1 exposure in swine

- (Peer Reviewed Journal)Buehler, J., Lager, K., Vincent, A., Miller, C., Thacker, E., Janke, B. 2014. Issues encountered in development of enzyme-linked immunosorbent assay for use in detecting influenza A virus subtype H5N1 exposure in swine. Journal of Veterinary Diagnostic Investigation. 26(2):277-281.Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations

- (Peer Reviewed Journal)Nelson, M.I., Wentworth, D.E., Culhane, M.R., Vincent, A.L., Viboud, C., LaPointe, M.P., Lin, X., Holmes, E.C., Detmer, S.E. 2014. Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations. Journal of Virology. 88(17):10110-10119.Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies

- (Peer Reviewed Journal)Sandbulte, M.R., Platt, R., Roth, J.A., Henningson, J.N., Gibson, K.A., Rajao, D.S., Loving, C.L., Vincent, A.L. 2014. Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies. Virology. 464-465:45–54.Mucosal correlates of cross-protection for live-attenuated influenza virus vaccines in pigs

- (Abstract Only)Cross-fostering to prevent maternal cell transfer did not prevent vaccine-associated enhanced respiratory disease that occurred following heterologous influenza challenge of pigs vaccinated in presence of maternal immunity

- (Peer Reviewed Journal)Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Zanella, E.L., Lager, K.M., Kehrli, Jr., M.E. 2014. Cross-fostering to prevent maternal cell transfer did not prevent vaccine-associated enhanced respiratory disease that occurred following heterologous influenza challenge of pigs vaccinated in presence of maternal immunity. Viral Immunology. 27(7):334-342.Immune response to influenza A virus hemagglutinin protein is sufficient to induce vaccine-associated enhanced respiratory disease

- (Abstract Only)Rajão, D.S., Loving, C.L., Gauger, P.C., Kitikoon, P., Vincent, A.L. 2014. Immune response to influenza A virus hemagglutinin protein is sufficient to induce vaccine-associated enhanced respiratory disease. American Society for Virology  33rd Annual Meeting. p. 199.A brief introduction to influenza A virus in swine

- (Book / Chapter)Vincent, A.L., Lager, K.M., Anderson, T.K. 2014. A brief introduction to influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 243-258.In vivo models for pathotyping and vaccine efficacy for swine influenza

- (Book / Chapter)Lager, K.M., Vincent, A.L. 2014. In vivo models for pathotyping and vaccine efficacy for swine influenza. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 355-361.Serum virus neutralization assay for detection and quantitation of serum neutralizing antibodies to influenza A virus in swine

- (Book / Chapter)Gauger, P.C., Vincent, A.L. 2014. Serum virus neutralization assay for detection and quantitation of serum neutralizing antibodies to influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 313-324.Microneutralization assay for swine influenza virus in swine serum

- (Book / Chapter)Kitikoon, P., Vincent, A.L. 2014. Microneutralization assay for swine influenza virus in swine serum. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 325-335.Enzyme-linked immunosorbent assay for detection of serum or mucosal isotype specific IgG and IgA whole virus antibody to influenza A virus in swine

- (Book / Chapter)Gauger, P.C., Loving, C.L., Vincent, A.L. 2014. Enzyme-linked immunosorbent assay for detection of serum or mucosal isotype specific IgG and IgA whole virus antibody to influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology: Animal Influenza Virus. 2nd edition. Springer New York, Humana Press. 1161:303-312.Hemagglutinin inhibition assay with swine sera

- (Book / Chapter)Kitikoon, P., Gauger, P.C., Vincent, A.L. 2014. Hemagglutinin inhibition assay with swine sera. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 295-301.Antibody secreting cell assay for influenza A virus in swine

- (Book / Chapter)Kitikoon, P., Loving, C.L., Vincent, A.L. 2014. Antibody secreting cell assay for influenza A virus in swine. In: Spackman, E., editor. Methods in Molecular Biology, Animal Influenza Virus. 2nd edition. New York, NY: Springer. p. 347-353.Influenza A virus pathogenesis and vaccination in swine

- (Book / Chapter)Rajao, D.S., Anderson, T.K., Gauger, P.C., Vincent, A.L. 2014. Pathogenesis and vaccination of influenza A virus in swine. In: Compans, R.W., Oldstone, M.B.A., editors. Influenza Pathogenesis and Control, Current Topics in Microbiology and Immunology. Switzerland: Springer International Publishing. p. 307-326.Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine

- (Peer Reviewed Journal)Lewis, N.S., Anderson, T.K., Kitikoon, P., Skepner, E., Burke, D.F., Vincent, A.L. 2014. Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine. Journal of Virology. 88(9):4752-4763.Detection and characterization of influenza A virus endemic circulation in neonatal and nursery pigs in a farm using an inactivated influenza vaccine

- (Abstract Only)Gauger, P.C., Dias, A.S., Vincent, A.L., Baker, R.B., Zhang, J., Kitikoon, P. 2014. Detection and characterization of influenza A virus endemic circulation in neonatal and nursery pigs in a farm using an inactivated influenza vaccine. Proceedings of the 45th American Association of Swine Veterinarians Annual Meeting. p. 51-54.Connecting the dots between swine influenza A virus surveillance and vaccines

- (Proceedings)Vincent, A.L., Anderson, T.K., Kitikoon, P., Lewis, N., Rajao, D., Campbell, B.A. 2014. Connecting the dots between swine influenza A virus surveillance and vaccines. Proceedings of the 45th American Association of Swine Veterinarians Annual Meeting. p. 527-532.Swine influenza virus vaccine research and technology: What does the future hold and what are our next steps?

- (Proceedings)Kehrli Jr, M.E., Vincent, A.L., Loving, C.L., Lager, K.M. 2013. Swine influenza virus vaccine research and technology: What does the future hold and what are our next steps? Swine Disease Conference Proceedings, November 14-15, 2013, Ames, Iowa. p. 16-20.Heterologous challenge of weaned piglets in the presence of maternal derived antibodies results in vaccine-associated enhanced respiratory disease

- (Abstract Only)Rajao, D., Vincent, A.L., Loving, C.L., Sandbulte, M., Kitikoon, P. 2013. Heterologous challenge of weaned piglets in the presence of maternal derived antibodies results in vaccine-associated enhanced respiratory disease [abstract]. 2013 Conference of Research Workers in Animal Diseases, December 8-10, 2013, Chicago, IL. Paper No. 090.Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus

- (Abstract Only)Rajao, D., Vincent, A.L., Loving, C.L., Sandbulte, M., Kitikoon, P. 2014. Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus. Proceedings of the 45th American Association of Swine Veterinarians Annual Meeting, p.41-47.Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus

- (Proceedings)Rajao, D., Vincent, A.L., Loving, C.L., Gauger, P.C., Sandbulte, M., Kitikoon, P. 2014. Maternal derived antibodies induce vaccine-associated enhanced respiratory disease in weaned pigs challenged with heterologous virus. Proceedings of 45th American Association of Swine Veterinarians Annual Meeting. p. 51-54.Lessons learned from influenza in swine and poultry

- (Abstract Only)Swine influenza virus vaccine serologic cross-reactivity to contemporary U.S. swine H3N2 and efficacy in pigs infected with an H3N2 similar to 2011-2012 H3N2v

- (Peer Reviewed Journal)Kitikoon, P., Gauger, P.C., Anderson, T.K., Culhane, M.R., Swenson, S., Loving, C.L., Perez, D.R., Vincent, A.L. 2013. Swine influenza virus vaccine serologic cross-reactivity to contemporary US swine H3N2 and efficacy in pigs infected with an H3N2 similar to 2011-2012 H3N2v. Influenza and Other Respiratory Viruses. 7(Suppl. 4):32-41.Population dynamics of co-circulating swine influenza A viruses in the United States from 2009-2012

- (Peer Reviewed Journal)Anderson, T.K., Nelson, M.I., Kitikoon, P., Swenson, S.L., Korslund, J.A., Vincent, A.L. 2013. Population dynamics of cocirculating swine influenza A viruses in the United States from 2009 to 2012. Influenza and Other Respiratory Viruses. 7(Suppl. 4):42-51.Influenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon

- (Peer Reviewed Journal)Buehler, J., Navi, D., Lorusso, A., Vincent, A., Lager, K., Miller, C.L. 2013. Influenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon. Journal of Virology. 87(19):10687-10699.The growing diversity of H3N2 influenza A virus in swine and the impact on control in swine and at the human animal interface

- (Proceedings)Vincent, A.L., Kitikoon, P., Anderson, T.K., Loving, C.L. 2013. The growing diversity of H3N2 influenza A virus in swine and the impact on control in swine and at the human animal interface. Proceedings of the 2013 Allen D Leman Swine Conference. p. 161-63.Efficacy of inactivated and live-attenuated influenza virus vaccines in pigs against infection and transmission of emerging H3N2 similar to the 2011-2012 H3N2v

- (Peer Reviewed Journal)Loving, C.L., Lager, K.M., Vincent, A.L., Brockmeier, S.L., Gauger, P.C., Anderson, T.K., Kitikoon, P., Perez, D.R., Kehrli, Jr., M.E. 2013. Efficacy in pigs of inactivated and live attenuated influenza virus vaccines against infection and transmission of an emerging H3N2 similar to the 2011-2012 H3N2v. Journal of Virology. 87(17):9895-903.Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease

- (Peer Reviewed Journal)Khurana, S., Loving, C.L., Manischewitz, J., King, L.R., Gauger, P.C., Henningson, J., Vincent, A.L., Golding, H. 2013. Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease. Science Translational Medicine. 5(200):200ra114.Vaccine-associated enhanced respiratory disease does not interfere with the adaptive immune response following challenge with pandemic A/H1N1 2009

- (Peer Reviewed Journal)Gauger, P.C., Loving, C.L., Lager, K.M., Janke, B.H., Kehrli, Jr., M.E., Roth, J.A., Vincent, A.L. 2013. Vaccine-associated enhanced respiratory disease does not interfere with the adaptive immune response following challenge with pandemic A/H1N1 2009. Viral Immunology. 26(5):314-321.Swine influenza - need for global surveillance and improved vaccines

- (Abstract Only)Human infections with influenza A(H3N2) variant virus in the United States, 2011-2012

- (Peer Reviewed Journal)Epperson, S., Jhung, M., Richards, S., Quinlisk, P., Ball, L., Moll, M., Boulton, R., Haddy, L., Biggerstaff, M., Brammer, L., Trock, S., Burns, E., Gomez, T., Wong, K.K., Katz, J., Lindstrom, S., Klimov, A., Bresee, J.S., Jernigan, D.B., Cox, N., Finelli, L., Influenza A(H3N2)v Virus Investigation Team (Vincent, A.L.). 2013. Human infections with influenza A(H3N2) variant virus in the United States, 2011-2012. Clinical Infectious Diseases. 57(S1):S4-S11.Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies

- (Abstract Only)Increased diversity of H3N2 influenza virus in pigs in the United States and implications for pigs and humans

- (Abstract Only)Genotype patterns of contemporary reassorted H3N2 virus in U.S. swine

- (Peer Reviewed Journal)Kitikoon, P., Nelson, M.I., Killian, M.L., Anderson, T.K., Koster, L., Culhane, M.R., Vincent, A.L. 2013. Genotype patterns of contemporary reassorted H3N2 virus in US swine. Journal of General Virology. 94(Pt 6):1236-1241.Cross-reactive, linear B cell epitopes of the influenza virus matrix protein 1

- (Abstract Only)Lin, K., Vincent, A.L., Roth, J.A., Kehrli, Jr., M.E., Lager, K.M., Ramamoorthy, S. 2013. Cross-reactive, linear B cell epitopes of the influenza virus matrix protein 1. In: Proceedings of the 16th Annual Conference on Vaccine Research. April 22-24, Baltimore, Maryland. p. 115.Pathogenicity and transmission of the novel A (H3N2v) influenza virus isolated from humans in experimentally inoculated pigs

- (Abstract Only)Review of influenza A virus in swine worldwide: a call for increased surveillance and research

- (Review Article)Vincent, A., Awada, L., Brown, I., Chen, H., Claes, F., Dauphin, G., Donis, R., Culhane, M., Hamilton, K., Lewis, N., Mumford, E., Nguyen, T., Parchariyanon, S., Pasick, J., Pavade, G., Pereda, A., Peiris, M., Saito, T., Swenson, S., Van Reeth, K., Webby, R., Wong, F., Ciacci-Zanella, J. 2014. Review of influenza A virus in swine worldwide: a call for increased surveillance and research. Zoonoses and Public Health. 61(1):4-17.Outbreak of influenza A (H3N2) in people and pigs at county fairs

- (Abstract Only)Swenson, S.L., Killian, M., Pogranichniy, R.N., Strasser, J., Lindstrom, S., Kitikoon, P., House, J., Lenz, S., Koster, L., Marsh, B., Vincent, A.L. 2013. Outbreak of influenza A (H3N2) in people and pigs at county fairs. Proceedings of the 44th American Association of Swine Veterinarians Annual Meeting. p. 417.Overview of swine influenza virus vaccine research and technology: What's on the horizon and what do we need to move forward?

- (Proceedings)Kehrli, Jr., M.E., Vincent, A.L., Gauger, P.C., Kitikoon, P., Anderson, T.K., Loving, C.L., Lager, K.M. 2013. Overview of swine influenza virus vaccine research and technology: What's on the horizon and what do we need to move forward? In: Proceedings of 44th Annual Meeting of the American Association of Swine Veterinarians, San Diego, CA. p. 517-519.Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs

- (Abstract Only)Loving, C.L., Braucher, D.R., Brockmeier, S.L., Vincent, A.L. 2012. Cross-reactive immune responses following vaccination with a live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Immunological Mechanisms of Vaccination, Keystone Symposia. Paper No. 2038.Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream C-gamma genes

- (Peer Reviewed Journal)Butler, J.E., Sun, X., Wertz, N., Vincent, A.L., Zanella, E.L., Lager, K.M. 2013. Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream C-gamma genes. Immunology. 138(2):134-144.Frequency of genomic reassortment of influenza A virus in North American swine, 1998-2011

- (Peer Reviewed Journal)Nelson, M.I., Detmer, S.E., Wentworth, D.E., Tan, Y., Schwartzbard, A., Halpin, R.A., Stockwell, T.B., Lin, X., Vincent, A.L., Gramer, M.R., Holmes, E.C. 2012. Genomic reassortment of influenza A virus in North American swine, 1998-2011. Journal of General Virology. 93(Pt 12):2584-2589.Intranasal vaccination with replication defective adenovirus-5 encoding influenza hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs

- (Peer Reviewed Journal)Braucher, D.R., Henningson, J.N., Loving, C.L., Vincent, A.L., Kim, E., Steitz, J., Gambotto, A.A., Kehrli, Jr., M.E. 2012. Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs. Clinical and Vaccine Immunology. 19(11):1722-1729.Strain-dependent effects of PB1-F2 of triple reassortant H3N2 influenza viruses in swine

- (Peer Reviewed Journal)Pena, L., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Perez, D.R. 2012. Strain-dependent effects of PB1-F2 of triple reassortant H3N2 influenza viruses in swine. Journal of General Virology. 93(10):2204-2214.Adenovirus vectored vaccines against influenza a virus do not result in vaccine associated enhanced respiratory disease following heterologous challenge in contrast to whole inactivated virus vaccine

- (Abstract Only)Henningson, J.N., Braucher, D.R., Vincent, A.L., Loving, C.L., Kitikoon, P., Gauger, P.C., Kehrli, M.E. 2012. Adenovirus vectored vaccines against influenza A virus do not result in vaccine associated enhanced respiratory disease following heterologous challenge in contrast to whole inactivated virus vaccine. American College of Veterinary Pathologists Meeting 63rd Annual Meeting. Paper No. E-2.Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine associated enhanced respiratory disease (VAERD)

- (Peer Reviewed Journal)Vincent, A.L., Ma, W., Lager, K.M., Richt, J.A., Janke, B.H., Sandbulte, M.R., Gauger, P.C., Loving, C.L., Webby, R.J., Garcia-Sastre, A. 2012. Live attenuated influenza vaccine provides superior protection from heterologous infection in pigs with maternal antibodies without inducing vaccine associated enhanced respiratory disease. Journal of Virology. 86(19):10597-10605.Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs

- (Peer Reviewed Journal)Loving, C.L., Vincent, A.L., Pena, L., Perez, D.R. 2012. Heightened adaptive immune responses following vaccination with a temperature-sensitive, live-attenuated influenza virus compared to adjuvanted, whole-inactivated virus in pigs. Vaccine. 30(40):5830-5838.Frequent global transmission of H1N1pdm09 influenza viruses from humans to swine, 2009-2011

- (Peer Reviewed Journal)Nelson, M.I., Gramer, M.R., Vincent, A.L., Holmes, E.C. 2012. Global transmission of influenza viruses from humans to swine. Journal of General Virology. 93(10):2195-2203.Flu virus continues to evolve in swine

- (Trade Journal)Gauger, P.C., Zhang, J., Vincent, A.L. 2012. Flu virus continues to evolve in swine. National Hog Farmer. Available: http://nationalhogfarmer.com/health/flu-virus-continues-evolve-swine.Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2

- (Abstract Only)Cheung, A.K., Kehrli, Jr., M.E., Lager, K.M., Gauger, P.C., Rohrer, G.A., Michael, D.D., Miller, L.C., Vincent, A.L., Braucher, D.R. 2012. Development of antinuclear antibodies and a genetic linkage in pigs infected with porcine circovirus type 2 [abstract]. IXth International Congress of Veterinary Virology. p. 189-190.Evolution of H3N2v viruses in North American swine and humans, 2009-2011

- (Peer Reviewed Journal)Nelson, M.I., Vincent, A.L., Kitikoon, P., Holmes, E.C., Gramer, M.R. 2012. The evolution of novel reassortant A/H3N2 influenza viruses in North American swine and humans, 2009-2011. Journal of Virology. 86(16):8872-8878.Simultaneous infection of pigs and people with triple reassortant swine influenza virus H1N1 at a U.S. county fair

- (Peer Reviewed Journal)Killian, M.L., Swenson, S.L., Vincent, A.L., Landgraf, J.G., Shu, B., Lindstrom, S., Xu, X., Klimov, A., Zhang, Y., Bowman, A.S. 2013. Simultaneous infection of pigs and people with triple-reassortant swine influenza virus H1N1 at a U.S. county fair. Zoonoses and Public Health. 60(3):196-201.Comparison of 2010-2011 H3N2 influenza A viruses isolated from swine and the A(H3N2)v isolated from humans in 2011

- (Abstract Only)Kitikoon, P., Vincent, A.L., Gauger, P., Schlink, S.N., Bayles, D.O., Gramer, M., Darnell, D., Webby, R., Lager, K.M., Swenson, S., Klimov, A. 2012. Comparison of 2010-2011 H3N2 influenza A viruses isolated from swine and the A(H3N2)v isolated from humans in 2011 [abstract]. American Society for Virology 31st Annual Meeting. p. 102.Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host

- (Peer Reviewed Journal)Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Lorusso, A., Loving, C.L., Brockmeier, S.L., Gauger, P.C., Janke, B.H., Gramer, M.R. 2012. Comparison of human-like H1 (delta-cluster) influenza A viruses in the swine host. Influenza Research and Treatment. Available: http://www.hindawi.com/journals/irt/2012/329029/.Influenza A virus and secondary bacterial infection in swine

- (Abstract Only)National surveillance for swine influenza virus in the United States, 2009-present

- (Proceedings)Schiltz, J., Korslund, J.A., Pyburn, D., Swenson, S., Tomlinson, S., Kasari, E.M., Vincent, A.L. 2012. National surveillance for swine influenza virus in the United States, 2009-present. Proceedings of the 22nd International Pig Veterinary Society Congress. p. 415.Pathogenicity and transmission in pigs of the novel A(H3N2)v influenza virus isolated from humans and characterization of swine H3N2 viruses isolated in 2010-2011

- (Peer Reviewed Journal)Kitikoon, P., Vincent, A.L., Gauger, P.C., Schlink, S.N., Bayles, D.O., Gramer, M.R., Darnell, D., Webby, R.J., Lager, K.M., Swenson, S.L., Klimov, A. 2012. Pathogenicity and transmission in pigs of the novel A(H3N2)v influenza virus isolated from humans and characterization of swine H3N2 viruses isolated in 2010-2011. Journal of Virology. 86(12):6804-6814.Restored PB1-F2 into the 2009 pandemic H1N1 influenza virus has minimal effects in swine

- (Peer Reviewed Journal)Pena, L., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Lorusso, A., Perez, D.R. 2012. Restored PB1-F2 into the 2009 pandemic H1N1 influenza virus has minimal effects in swine. Journal of Virology. 86(10):5523-5532.Kinetics of lung lesion development and pro-inflammatory cytokine response in pigs with vaccine-associated enhanced respiratory disease induced by challenge with pandemic (2009) A/H1N1 influenza virus

- (Peer Reviewed Journal)Gauger, P.C., Vincent, A.L., Loving, C.L., Henningson, J.N., Lager, K.M., Janke, B.H., Kehrli Jr, M.E., Roth, J.A. 2012. Kinetics of lung lesion development and pro-inflammatory cytokine response in pigs with vaccine-associated enhanced respiratory disease induced by challenge with pandemic (2009) A/H1N1 influenza virus. Veterinary Pathology. 49(6):900-912.Global coordination for swine influenza virus surveillance and research: what are we missing from the big picture?

- (Proceedings)Vincent, A.L., Kitikoon, P., Gauger, P.C., Gramer, M.R., Lorusso, A., Lager, K.M., Ciacci-Zanella, J.R. 2012. Global coordination for swine influenza virus surveillance and research: what are we missing from the big picture? In: Proceedings of the 43rd American Association of Swine Veterinarians Annual Meeting, March 10-13, 2012, Denver, Colorado. p. 507-512.Swine influenza virus: epidemiology and vaccine concerns

- (Proceedings)Gauger, P.C., Vincent, A.L. 2012. Swine influenza virus: epidemiology and vaccine concerns. In: Proceedings of the 19th Annual Swine Disease Conference for Swine Practitioners, November 10-11, 2011, Ames, Iowa. p. 13-21.Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs

- (Peer Reviewed Journal)Kappes, M.A., Sandbulte, M.R., Platt, R., Wang, C., Lager, K.M., Henningson, J.N., Lorusso, A., Vincent, A.L., Loving, C.L., Roth, J.A., Kehrli Jr, M.E. 2012. Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs. Vaccine. 30(2):280-288.The changing face of swine influenza virus

- (Trade Journal)Vincent, A.L., Gauger, P.C. 2011. The changing face of swine influenza virus. Pork Magazine. Available: http://www.porknetwork.com/pork/smart-thinking/The-Changing-Face-of-Swine-Influenza-Virus-133249878.html.Influenza A virus in pigs – protection, provocation and predisposition

- (Abstract Only)Modified live virus vaccine induces a distinct immune response profile compared to inactivated influenza A virus vaccines in swine

- (Abstract Only)Gauger, P., Vincent, A., Loving, C., Lorusso, A., Lager, K., Pena, L., Perez, D. 2011. Modified live virus vaccine induces a distinct immune response profile compared to inactivated influenza A virus vaccines in swine [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 148.Intranasal vaccination with Ad5-encoding influenza HA elicits sterilizing immunity to homologous challenge and partial protection to heterologous challenge in pigs

- (Abstract Only)Braucher, D.R., Henningson, J.N., Loving, C.L., Vincent, A.L., Kim, E., Steitz, J., Gambotto, A.A., Kehrli, Jr., M.E. 2011. Intranasal vaccination with Ad5-encoding influenza HA elicits sterilizing immunity to homologous challenge and partial protection to heterologous challenge in pigs [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 131.Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs – exacerbation associated with vaccination

- (Abstract Only)Loving, C.L., Vincent, A.L., Brockmeier, S.L., Henningson, J.N., Braucher, D.R., De Souza Rajao, D. 2011. Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs - exacerbation associated with vaccination [abstract]. Autumn Immunology Conference. Poster No. 140.DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs

- (Peer Reviewed Journal)Gorres, J.P., Lager, K.M., Kong, W.P., Royals, M., Todd, J.P., Vincent, A.L., Wei, C.J., Loving, C.L., Zanella, E.L., Janke, B., Kehrli, Jr., M.E., Nabel, G.J., Rao, S.S. 2011. DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs. Clinical and Vaccine Immunology. 18(11):1987-1995.Isolation and characterization of pandemic H1N1 influenza viruses in pigs in Brazil

- (Peer Reviewed Journal)Schaefer, R., Zanella, J.R.C., Brentano, L., Vincent, A.L., Ritterbusch, G.A., Silveira, S., Caron, L., Mores, N. 2011. Isolation and characterization of pandemic H1N1 influenza viruses in pigs in Brazil. Pesquisa Veterinaria Brasileira. 31(9):761-767.A novel monoclonal antibody effective against lethal challenge with swine-lineage and 2009 pandemic H1N1 influenza viruses in mice

- (Peer Reviewed Journal)Shao, H., Ye, J., Vincent, A.L., Edworthy, N., Ferrero, A., Qin, A., Perez, D. 2011. A novel monoclonal antibody effective against lethal challenge with swine-lineage and 2009 pandemic H1N1 influenza viruses in mice. Virology. 417(2):379-384.Leukogram abnormalities in gnotobiotic pigs infected with porcine circovirus type 2

- (Peer Reviewed Journal)Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Cheung, A.K., Butler, J.E., Kehrli, Jr., M.E. 2011. Leukogram abnormalities in gnotobiotic pigs infected with porcine circovirus type 2. Veterinary Microbiology. 154(1-2):185-190.Characterization of H1N1 swine influenza viruses circulating in Canadian pigs in 2009

- (Peer Reviewed Journal)Nfon, C.K., Berhane, Y., Hisanaga, T., Zhang, S., Handel, K., Kehler, H., Labrecque, O., Lewis, N.S., Vincent, A.L., Copps, J., Alexandersen, S., Pasick, J. 2011. Characterization of H1N1 swine influenza viruses circulating in Canadian pigs in 2009. Journal of Virology. 85(17):8667-8679.Antigenic map of hemagglutinin (H) 1 proteins of 2010-2011 swine influenza viruses (SIV) in the U.S. swine population

- (Abstract Only)Postweaning multisystemic wasting syndrome produced in gnotobiotic pigs following exposure to various amounts of porcine circovirus type 2a or type 2b

- (Peer Reviewed Journal)Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2011. Postweaning multisystemic wasting syndrome produced in gnotobiotic pigs following exposure to various amounts of porcine circovirus type 2a or type 2b. Veterinary Microbiology. 153(3-4):229-239.Comparison of Humoral and Cellular Immune Responses to Inactivated Swine Influenza Virus Vaccine in Weaned Pigs

- (Peer Reviewed Journal)Platt, R., Vincent, A.L., Gauger, P.C., Loving, C.L., Zanella, E.L., Lager, K.M., Kehrli, Jr., M.E., Kimura, K., Roth, J.A. 2011. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs. Veterinary Immunology and Immunopathology. 142(3-4):252-257.Influenza A virus in swine - moving beyond 2009

- (Proceedings)Vincent, A.L., Lorusso, A., Lager, K.M., Gauger, P.C., Gramer, M.R., Ciacci-Zanella, J.R. 2011. Influenza A virus in swine - moving beyond 2009. In: Proceedings of the 6th International Symposium on Emerging and Re-emerging Pig Diseases, June 12-15, 2011, Barcelona, Spain. p. 35-37.Spatial dynamics of human-origin H1 influenza A v irus in North American swine

- (Peer Reviewed Journal)Nelson, M.I., Lemey, P., Tan, Y., Vincent, A., Lam, T.T-Y., Detmer, S., Viboud, C., Suchard, M.A., Rambaut, A., Holmes, E.C., Gramer, M. 2011. Spatial dynamics of human-origin H1 influenza A virus in North American swine. PLoS Pathogens. 7(6):e1002077.Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus

- (Peer Reviewed Journal)Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M., Janke, B.H., Kehrli, Jr., M.E., Roth, J.A. 2011. Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (delta-cluster) H1N2 vaccine and challenged with pandemic 2009 H1N1 influenza virus. Vaccine. 29(15):2712-2719.Utility of a Panviral Microarray for Detection of Swine Respiratory Viruses in Clinical Samples

- (Peer Reviewed Journal)Nicholson, T.L., Kukielka, D., Vincent, A.L., Brockmeier, S.L., Miller, L.C., Faaberg, K.S. 2011. Utility of a panviral microarray for detection of swine respiratory viruses in clinical samples. Journal of Clinical Microbiology. 49(4):1542-1548.Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States

- (Peer Reviewed Journal)Chen, L.M., Rivailler, P., Hossain, J.M., Carney, P., Balish, A., Perry, I., Davis, C.T., Garten, R., Shu, B., Xu, X., Klimov, A., Paulson, J.C., Cox, N.J., Swenson, S., Stevens, J., Vincent, A., Gramer, M., Donis, R.O. 2011. Receptor specificity of subtype H1 influenza A viruses isolated from swine and humans in the United States. Virology. 412(2):401-410.Immune responses elicited to a live-attenuated influenza virus vaccine compared to a traditional whole-inactivated virus vaccine for pandemic H1N1in pigs

- (Abstract Only)Loving, C.L., Vincent, A.L., Pena, L., Perez, D. 2011. Immune responses elicited to a live-attenuated influenza virus vaccine compared to a traditional whole-inactivated virus vaccine for pandemic H1N1 in pigs [abstract]. Keystone Symposium, Immunity in the Respiratory Tract. Poster No. 228. p. 163.Innate immune responses to pathogens involved in the porcine respiratory disease complex

- (Abstract Only)Brockmeier, S.L., Loving, C.L., Vincent, A.L. 2011. Innate immune responses to pathogens involved in the porcine respiratory disease complex [abstract]. Keystone Symposia, Immunity in the Respiratory Tract. Poster No. 114. p. 149.Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008

- (Peer Reviewed Journal)Lorusso, A., Vincent, A.L., Harland, M.L., Alt, D., Bayles, D.O., Swenson, S.L., Gramer, M.R., Russel, C.A., Smith, D.J., Lager, K.M., Lewis, N.S. 2011. Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008. Journal of General Virology. 92(Pt 4):919-930.Pandemic H1N1 influenza: zoonoses are a two-way street

- (Abstract Only)Innate Immune Responses are Enhanced in Pigs After Sequential Infection with Influenza Virus and Haemophilus parasuis

- (Abstract Only)Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Innate immune responses are enhanced in pigs after sequential infection with influenza virus and Haemophilus parasuis [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 165.Modifications in the Polymerase Genes of a Swine-Like Triple Reassortant Influenza Virus to Generate Live Attenuated Vaccines Against 2009 Pandemic H1N1 Viruses

- (Peer Reviewed Journal)Pena, L., Vincent, A.L., Ye, J., Ciacci-Zanella, J.R., Angel, M., Lorusso, A., Gauger, P.C., Janke, B.H., Loving, C.L., Perez, D.R. 2011. Modifications in the polymerase genes of a swine-like triple reassortant influenza virus to generate live attenuated vaccines against 2009 pandemic H1N1 Viruses. Journal of Virology. 85(1):456-469.Swine Influenza Virus: Emerging Understandings

- (Proceedings)Vincent, A.L., Lorusso, A., Lager, K.M., Gauger, P.C., Gramer, M.R., Ciacci-Zanella, J.R. 2010. Swine influenza virus: emerging understandings. In: Proceedings of 18th Annual Swine Disease Conference for Swine Practitioners, November 4-5, 2010, Ames, IA. p. 57-62.Genetic and Antigenic Characterization of H1 Influenza Viruses from United States Swine Prior to the Emergence of the 2009 Pandemic H1N1

- (Abstract Only)Lorusso, A., Vincent, A., Harland, M., Alt, D., Bayles, D., Swenson, S., Gramer, M., Russell, C., Smith, D., Lager, K., Lewis, N. 2010. Genetic and antigenic characterization of H1 Influenza Viruses from United States swine prior to the emergence of the 2009 pandemic H1N1 [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 194.Comparison of Humoral and Cellular Immune Responses to Inactivated Swine Influenza Virus Vaccine in Weaned Pigs

- (Abstract Only)Platt, R., Gauger, P., Kimura, K., Roth, J., Vincent, A., Loving, C., Zanella, E., Lager, K., Kehrli, M. 2010. Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 085P/85P.Pathogenesis Studies of the 2009 Pandemic Influenza Virus and Pseudorabies Virus From Wild Pigs In Swine

- (Proceedings)Lager, K.M., Vincent, A.L., Ciacci-Zanella, J.R., Zanella, E.L., Miller, L.C., Kehrli, Jr., M.E. 2010. Pathogenesis studies of the 2009 pandemic influenza virus and pseudorabies virus from wild pigs in swine. In: Proceedings of the Brazilian Society for Virology XXI Meeting, October 18-20, 2010, Gramado, Rio Grande do Sul, Brazil. p. 33-34.Safety and efficacy of a novel live attenuated influenza vaccine against pandemic H1N1 in swine

- (Peer Reviewed Journal)Pena, L., Vincent, A.L., Ye, J., Ciacci-Zanella, J.E., Angel, M., Lorusso, A., Gauger, P.C., Janke, B.H., Loving, C.L., Perez, D.R. 2011. Safety and efficacy of a novel live attenuated influenza vaccine against pandemic H1N1 in swine. Influenza and Other Respiratory Viruses. 5(S1):341-344.A monoclonal antibody-based ELISA for differential diagnosis of 2009 pandemic H1N1

- (Peer Reviewed Journal)Shao, H., Ye, J., Vincent, A.L., Song, H., Hickman, D., Qi, A., Lamichhane, C., Perez, D.R. 2011. A monoclonal antibody-based ELISA for differential diagnosis of 2009 pandemic H1N1. Influenza and Other Respiratory Viruses. 5(Suppl.1):138-142.Influenza Vaccination in the Face of Maternal Antibody Results in Enhanced Pneumonia Following Heterologous, Homosubtypic Influenza Challenge

- (Abstract Only)Loving, C.L., Brockmeier, S.L., Vincent, A.L., Gauger, P.C., Kehrli, Jr., M.E. 2010. Influenza vaccination in the face of maternal antibody results in enhanced pneumonia following heterologous, homosubtypic influenza challenge [abstract]. Keystone Symposia, Immunological Mechanisms of Vaccination. Paper No. 243.Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions

- (Peer Reviewed Journal)Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Influenza Virus Coinfection with Bordetella bronchiseptica Enhances Bacterial Colonization and Host Responses Exacerbating Pulmonary Lesions. Microbial Pathogenesis. 49(5):237-245.Enhanced Pneumonia and Proinflammatory Cytokine Response in Pigs Challenged with Pandemic 2009 A/H1N1 Influenza Virus Following Vaccination with an Inactivated delta-Cluster H1N2 Virus

- (Abstract Only)Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M., Janke, B.A., Roth, J.A. 2010. Enhanced pneumonia and proinflammatory cytokine response in pigs challenged with pandemic 2009 A/H1N1 influenza virus following vaccination with an inactivated delta-cluster H1N2 virus [abstract]. International Conference on Emerging Infectious Diseases. Paper No. L1345.Zoonoses: USDA ARS Lessons Learned During Novel Influenza H1N1 Investigations

- (Abstract Only)Vincent, A.L. 2010. Zoonoses: USDA ARS Lessons Learned During Novel Influenza H1N1 Investigations [abstract]. American Veterinary Medical Association 147th Annual Convention. Paper No. 8515.Development and validation of a real-time RT-PCR assay for the 2009 pandemic H1N1 virus in veterinary specimens

- (Abstract Only)Spackman, E., Suarez, D.L., Killian, M.L., Koster, L., Swenson, S., Pedersen, J., Vincent, A.L., Lager, K.M., Jenkins-Moore, M., Schmitt, B. 2010. Development and validation of a real-time RT-PCR assay for the 2009 pandemic H1N1 virus in veterinary specimens [abstract]. Swine Origin H1N1: The First Pandemic of the 21st Century meeting, April 18-20, 2010, Atlanta, Georgia. p. 30.Investigation of the Function of the Influenza A Virus PB1-F2 Protein During Infection of Swine and Human Cells with a Predominant Circulating Swine Virus Isolate

- (Abstract Only)Buehler, J., Mccullough, D., Loving, C.L., Vincent, A.L., Lager, K.M., Miller, C. 2010. Investigation of the Function of the Influenza A Virus PB1-F2 Protein During Infection of Swine and Human Cells with a Predominant Circulating Swine Virus Isolate [abstract]. American Society for Virology Meeting. p. 279.Susceptibility of Swine to Low Pathogenic H5 and H7 Avian Influenza Viruses

- (Proceedings)Lager, K.M., Vincent, A.L., Gauger, P.C., Senne, D.A., Swayne, D.E., Miller, L.C., Richt, J., Ma, W., Suarez, D.L., Kehrli Jr, M.E. 2010. Susceptibility of Swine to Low Pathogenic H5 and H7 Avian Influenza Viruses. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 79.Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection

- (Proceedings)Loving, C.L., Brockmeier, S., Vincent, A.L. 2010. Prior Swine Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus parasuis Infection. In: Proceedings of the Pig Veterinary Society International Congress, July 18-21, 2010, Vancouver, Canada. p. 264.Discovery of Antinuclear Antibodies in Pigs Infected with Porcine Circovirus Type 2

- (Proceedings)Kehrli, Jr., M.E., Gauger, P.C., Cheung, A.K., Vincent, A.L., Lager, K.M. 2010. Discovery of Antinuclear Antibodies in Pigs Infected with Porcine Circovirus Type 2. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 332.Efficacy of Inactivated Swine Influenza Virus Vaccines Against 2009 H1N1 Influenza Virus in Pigs

- (Proceedings)Vincent, A.L., Ciacci-Zanella, J.R., Lorusso, A., Gauger, P.C., Zanella, E.R., Kehrli, Jr., M.E., Janke, B.H., Lager, K.M. 2010. Efficacy of Inactivated Swine Influenza Virus Vaccines Against 2009 H1N1 Influenza Virus in Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 299.Genetic and Antigenic Characterization of 2008 Swine Influenza Viruses from the United States

- (Proceedings)Vincent, A.L., Harland, M.L., Lorusso, A., Alt, D.P., Bayles, D.O., Swenson, S.L., Gramer, M.R., Lager, K.M., Lewis, N. 2010. Genetic and Antigenic Characterization of 2008 Swine Influenza Viruses from the United States. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 259.Experimental Challenge with Two Isolates of 2009 A/H1N1 in Weaned Pigs

- (Proceedings)Vincent, A.L., Ciacci Zanella, J.R., Lorusso, A., Zanella, E.L., Lager, K.M., Gauger, P.C., Janke, B.H., Kehrli, Jr., M.E. 2010. Experimental Challenge with Two Isolates of 2009 A/H1N1 in Weaned Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 74.Human-Like H1 (Delta-Cluster) Swine Influenza Virus (SIV) Can Efficiently Replicate, Transmit, Cause Lung Pathology and Induce Humoral Immune Responses in the Swine Host

- (Proceedings)Ciacci Zanella, J.R., Vincent, A.L., Zanella, E.L., Brockmeier, S. 2010. Human-Like H1 (Delta-Cluster) Swine Influenza Virus (SIV) Can Efficiently Replicate, Transmit, Cause Lung Pathology and Induce Humoral Immune Responses in the Swine Host. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 262.Challenge of Pigs with Natural Immunity to H1 and H3 Swine Influenza Virus with Pandemic 2009 H1N1 Influenza Virus

- (Proceedings)Ciacci Zanella, J.R., Lager, K.M., Vincent, A.L., Zanella, E.L., Gava, D. 2010. Challenge of Pigs with Natural Immunity to H1 and H3 Swine Influenza Virus with Pandemic 2009 H1N1 Influenza Virus. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 253.Enhanced Pneumonia With Pandemic 2009 A/H1N1 Swine Influenza Virus in Pigs

- (Proceedings)Gauger, P.C., Vincent, A.L., Loving, C.L., Lager, K.M. 2010. Enhanced Pneumonia With Pandemic 2009 A/H1N1 Swine Influenza Virus in Pigs. In: Proceedings of the International Pig Veterinary Society Congress, July 18-21, 2010, Vancouver, Canada. p. 255.A Set of Novel Monoclonal Antibodies Against Swine-Origin Pandemic H1N1 Differentiate Swine H1N1 and Human Seasonal H1N1

- (Abstract Only)Shao, H., Ye, J., Song, H., Lamichhane, C., Qin, A., Vincent, A.L., Perez, D.R. 2010. A Set of Novel Monoclonal Antibodies Against Swine-Origin Pandemic H1N1 Differentiate Swine H1N1 and Human Seasonal H1N1 [abstract]. International Symposium on Neglected Influenza Viruses. Poster #P-022. p. 41.One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection in Swine Samples

- (Proceedings)Lorusso, A., Faaberg, K.S., Killian, M., Koster, L., Vincent, A.L. 2010. One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection in Swine Samples [abstract]. American Association of Swine Veterinarians. American Association of Swine Veterinarians. p. 369.Identification and Molecular Cloning of a Novel Porcine Parvovirus

- (Peer Reviewed Journal)Cheung, A.K., Wu, G., Wang, D., Bayles, D.O., Lager, K.M., Vincent, A.L. 2010. Identification and Molecular Cloning of a Novel Porcine Parvovirus. Archives of Virology. 155(5):801-806.Antecedent Influenza Virus Infection Enhances Pulmonary Responses to Secondary Haemophilus Infection in a Porcine Co-Infection Model

- (Abstract Only)Loving, C.L., Brockmeier, S.L., Vincent, A.L. 2010. Antecedent Influenza virus infection enhances pulmonary responses to secondary Haemophilus infection in a porcine co-infection model [abstract]. American Association of Immunologists. Paper No. 803219.Efficacy of Inactivated Swine Influenza Virus Vaccines Against the 2009 A/H1N1 Influenza Virus in Pigs

- (Peer Reviewed Journal)Vincent, A.L., Ciacci-Zanella, J.R., Lorusso, A., Gauger, P.C., Zanella, E.L., Kehrli Jr, M.E., Janke, B.H., Lager, K.M. 2010. Efficacy of Inactivated Swine Influenza Virus Vaccines Against the 2009 A/H1N1 Influenza Virus in Pigs. Vaccine 28(15):2782-2787.Research Updates: Experimental Evaluation of 2009 Pandemic A/H1N1 in Pigs

- (Proceedings)Vincent, A.L., Lager, K.M., Harland, M.L., Lorusso, A., Ciacci-Zanella, J.R., Zanella, E.L., Kehrli, Jr., M.E., Gauger, P.C., Janke, B.H., Klimov, A. 2010. Research Updates: Experimental Evaluation of 2009 Pandemic A/H1N1 in Pigs. In: Proceedings of the 41st Annual Meeting of the American Association of Swine Veterinarians, March 6-9, 2010, Omaha, Nebraska. p. 495-497.Summary of Control Issues for Swine Influenza

- (Abstract Only)Vincent, A.L., Lager, K.M., Richt, J.A., Ma, W., Janke, B.H. 2010. Summary of control issues for swine influenza [abstract]. International Symposium on Neglected Influenza Viruses. p. 22.One-Step Real-Time RT-PCR for Pandemic Influenza A Virus (H1N1) 2009 Matrix Gene Detection in Swine Samples

- (Peer Reviewed Journal)Lorusso, A., Faaberg, K.S., Killian, M., Koster, L., Vincent, A.L. 2010. One-Step Real-Time RT-PCR for Pandemic Influenza A Virus (H1N1) 2009 Matrix Gene Detection in Swine Samples. Journal of Virological Methods. 164(1-2):83-87.Experimental Inoculation of Pigs with Pandemic H1N1 2009 Virus and HI Cross-Reactivity with Contemporary Swine Influenza Virus Antisera

- (Peer Reviewed Journal)Vincent, A.L., Lager, K.M., Faaberg, K.S., Harland, M., Zanella, E.L., Zanella, J.R., Kehrli, Jr., M.E., Janke, B.H., Klimov, A. 2009. Experimental Inoculation of Pigs with Pandemic H1N1 2009 Virus and HI Cross-Reactivity with Contemporary Swine Influenza Virus Antisera. Influenza and Other Respiratory Viruses. 4(2):53-60.Absence of Pandemic H1N1 Influenza A Virus in Fresh Pork

- (Peer Reviewed Journal)Vincent, A.L., Lager, K.M., Harland, M., Lorusso, A., Zanella, E., Ciacci-Zanella, J.R., Kehrli, Jr., M.E., Klimov, A. 2009. Absence of Pandemic H1N1 Influenza A Virus in Fresh Pork. PLoS ONE. 4:(12):e8367.Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions

- (Abstract Only)Loving, C.L., Brockmeier, S.L., Vincent, A.L., Palmer, M.V., Sacco, R.E., Nicholson, T.L. 2010. Swine influenza virus co-infection with Bordetella bronchiseptica enhances bacterial colonization and host immune responses exacerbating pulmonary lesions [abstract]. Conference Research Workers Disease Meeting. Paper No. 130.Swine Influenza Update

- (Proceedings)Lager, K.M., Vincent, A.L., Ciacci-Zanella, J.R., Zanella, E.L., Lorusso, A., Faaberg, K.S., Kehrli, Jr., M.E. 2009. Swine influenza update. In: Proceedings of the 17th Annual Swine Disease Conference, November 5-6, 2009, Iowa State University, Ames, Iowa. pp. 128-131.Identification and Characterization of a Highly Virulent Triple Reassortant H1N1 Swine Influenza Virus in the Midwest of the United States

- (Peer Reviewed Journal)Ma, W., Vincent, A.L., Lager, K.M., Janke, B.H., Henry, S.C., Rowland, R.R., Hesse, R.A., Richt, J.A. 2010. Identification and Characterization of a Highly Virulent Triple Reassortant H1N1 Swine Influenza Virus in the United States. Virus Genes. 40(1):28-36.One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection and Quantitation in Clinical Samples

- (Abstract Only)Lorusso, A., Faaberg, K.S., Killian, M., Koster, L., Vincent, A.L. 2010. One Step Real-Time RT-PCR for 2009 Pandemic H1N1 Matrix Gene Detection and Quantitation in Clinical Samples [abstract]. American Association of Swine Veterinarians. p. 369.Detection of Anti-Influenza A Nucleoprotein Antibodies in Pigs Using a Commercial Influenza Epitope-Blocking Enzyme-Linked Immunosorbent Assay Developed for Avian Species

- (Peer Reviewed Journal)Ciacci-Zanella, J.R., Vincent, A.L., Prickett, J.R., Zimmerman, S.M., Zimmerman, J.J. 2010. Detection of Anti-Influenza A Nucleoprotein Antibodies in Pigs Using a Commercial Influenza Epitope-Blocking Enzyme-Linked Immunosorbent Assay Developed for Avian Species. Journal of Veterinary Diagnostic Investigation. 22(1):3-9.Swine Influenza Matrix 2 (M2) Protein Contributes to Protection Against Infection with Different H1 Swine Influenza Virus (SIV) Isolates

- (Peer Reviewed Journal)Kitikoon, P., Vincent, A.L., Janke, B.H., Erickson, B., Strait, E.L., Yu, S., Gramer, M.R., Thacker, E.L. 2009. Swine Influenza Matrix 2 (M2) Protein Contributes to Protection Against Infection with Different H1 Swine Influenza Virus (SIV) Isolates. Vaccine. 28(2):523-531.Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States

- (Peer Reviewed Journal)Vincent, A.L., Ma, W., Lager, K.M., Gramer, M.R., Richt, J.A., Janke, B.H. 2009. Characterization of a Newly Emerged Genetic Cluster of H1N1 and H1N2 Swine Influenza Virus in the U.S. Virus Genes. 39(2):176-185.Vaccine efficacy and immune response to swine influenza virus challenge in pigs infected with porcine reproductive and respiratory syndrome virus at the time of SIV-vaccination

- (Peer Reviewed Journal)Kitikoon, P., Vincent, A.L., Jones, K.R., Nilubol, D., Yu, S., Janke, B.H., Thacker, B.J., Thacker, E.L. 2009. Vaccine Efficacy and Immune Response to Swine Influenza Virus Challenge in Pigs Infected with Porcine Reproductive and Respiratory Syndrome Virus at the Time of SIV-Vaccination. Veterinary Microbiology. 139(3-4):235-244.Clinical and pathological responses of pigs from two genetically diverse commercial lines to porcine respiratory and reproductive syndrome virus infection

- (Peer Reviewed Journal)Doeschl-Wilson, A.B., Kyriazakis, I., Vincent, A., Rothschild, M.F., Thacker, E., Galina-Pantoja, L. 2009. Clinical and Pathological Responses of Pigs from Two Genetically Diverse Commercial Lines to Porcine Respiratory and Reproductive Syndrome Virus Infection. Journal of Animal Science. 87(5):1638-1647.Characterization of an Influenza A Virus Isolated from Pigs During an Outbreak of Respiratory Disease in Swine and People at a County Fair in the United States

- (Peer Reviewed Journal)Vincent, A.L., Swenson, S.L., Lager, K.M., Gauger, P.C., Loiacono, C., Zhang, Y. 2009. Characterization of an Influenza A Virus Isolated from Pigs During an Outbreak of Respiratory Disease in Swine and People at a County Fair in the United States. Veterinary Microbiology. 137(1-2):51-59.Development of a replication defective adenovirus 5 vector expressing porcine interleukin-18 and a mutated analog

- (Abstract Only)Kappes, M.A., Ma, W., Richt, J.A., Lager, K.M., Vincent, A.L., Roth, J.A., Murtaugh, M.P., Kehrli, Jr., M.E. 2008. Development of a Replication Defective Adenovirus 5 Vector Expressing Porcine Interleukin-18 and a Mutated Analog [abstract]. Conference of Research Workers in Animal Diseases. Paper No. 99P. p. 121.The role of swine in the generation of novel influenza viruses

- (Peer Reviewed Journal)Ma, W., Lager, K.M., Vincent, A.L., Janke, B.H., Gramer, M.R., Richt, J.A. 2009. The Role of Swine in the Generation of Novel Influenza Viruses. Zoonoses and Public Health. 56(6-7):326-337.Differences in immune response of pigs challenged with a high versus low dose inoculum of porcine reproductive and respiratory syndrome virus

- (Peer Reviewed Journal)Loving, C.L., Brockmeier, S.L., Vincent, A.L., Lager, K.M., Sacco, R.E. 2008. Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virus. Viral Immunology. 21(3):315-325.Investigating the porcine immune reponse to Haemophilus parasuis

- (Abstract Only)Experimental Evaluation of a Swine Influenza Virus Isolated from a County Fair Outbreak in the United States

- (Proceedings)Vincent, A.L., Swenson, S.L., Lager, K.M., Gauger, P.C., Loiacono, C.M., Beach, T., Landgraf, J., Zhang, Y. 2008. Experimental Evaluation of a Swine Influenza Virus Isolated from a County Fair Outbreak in the United States. In: Proceedings of the 20th International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. p. 7.Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica

- (Proceedings)Brockmeier, S., Vincent, A.L., Loving, C.L., Nicholson, T.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica.  In: Proceedings of the 20th International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. 1:10.Pathogenesis of PCV2a and PCV2b virus in germ-free pigs

- (Proceedings)Gauger, P.C., Lager, K.M., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2008. Pathogenesis of PCV2a and PCV2b Virus in Germ-Free pigs. In: Proceedings of the International Pig Veterinary Society Congress, June 22-26, 2008, Durban, South Africa. Paper No. OR.01.28.Swine Influenza Viruses: a North American Perspective

- (Review Article)Vincent, A.L., Ma, W., Lager, K.M., Janke, B.H., Richt, J.A. 2008. Swine Influenza Viruses: a North American Perspective. Advances in Virus Research. 72:127:154.Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica

- (Abstract Only)Brockmeier, S., Loving, C.L., Nicholson, T.L., Vincent, A.L., Sacco, R.E. 2008. Early Induction of Cytokines in Pigs Coinfected with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. American Society for Microbiology Meeting, June 2-4, 2008, Boston, Massachusetts. 2008 CDROM.Coinfection of Pigs with Swine Influenza Virus and Bordetella bronchiseptica

- (Abstract Only)Brockmeier, S., Vincent, A.L., Nicholson, T.L., Sacco, R.E., Palmer, M.V. 2007. Coinfection of Pigs with Swine Influenza Virus and Bordetella bronchiseptica [abstract]. In: United States Japan Natural Resources Animal and Avian Health Panel, December 5, 2007, Tsukuba, Japan. p. 25.Identification of H2N3 influenza A viruses from swine in the United States

- (Peer Reviewed Journal)Ma, W., Vincent, A.L., Gramer, M.R., Brockwell, C.B., Lager, K.M., Janke, B.H., Gauger, P.C., Patnayak, D.P., Webby, R.J., Richt, J.A. 2007. Identification of H2N3 influenza A viruses from swine in the United States. Proceedings of the National Academy of Sciences. 104(52):20949-20954.Viral Reassortment and Transmission after Coinfection of Pigs with two Swine Influenza Viruses

- (Abstract Only)Ma, W., Lager, K.M., Fleckenstein, E.S., Lekcharoensuk, P., Janke, B.H., Vincent, A.L., Webby, R.J., Richt, J.A. 2007. Viral reassortment and transmission after coinfection of pigs with 2 swine influenza viruses [abstract]. Conference of Research Workers in Animal Diseases Annual Meeting. Paper No. 146. p. 147.Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine

- (Peer Reviewed Journal)Vincent, A.L., Ma, W., Lager, K.M., Janke, B.H., Webby, R.J., Garcia-Sastre, A., Richt, J.A. 2007. Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine. Vaccine. 25:7999-8009.VIRUS VACCINE RESEARCH AT THE NATIONAL ANIMAL DISEASE CENTER: LESSONS FROM SWINE INFLUENZA VIRUS AND BOVINE VIRAL DIARRHEA VIRUS

- (Abstract Only)Kehrli, Jr., M.E., Vincent, A.L., Richt, J.A., Wesley, R.D., Lager, K.M., Ridpath, J.F., Kimura, K., Roth, J.A. 2007. Virus vaccine research at the National Animal Disease Center: lessons from swine influenza virus and bovine viral diarrhea virus [abstract]. The Changing Landscape of Vaccine Development: Vaccines for Global Health. The University of Texas Medical Branch, Sealy Center for Vaccine Development. p. 14Reproduction of PMWS of high mortality with a porcine circovirus type 2-group 1 isolate

- (Proceedings)Cheung, A.K., Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E. 2007. Reproduction of PMWS of high mortality with a porcine circovirus type 2-group 1 isolate.  In: Proceedings of the 13th International World Association of Veterinary Laboratory Diagnosticians Symposium, November 11-14, 2007, Melbourne, Australia. p. 213.Characterization of the novel H2N3 influenza virus subtype isolated from U.S. pigs

- (Abstract Only)Ma, W., Vincent, A., Gramer, M., Brockwell, C., Janke, B., Lager, K., Gauger, P., Webby, R., Richt, J. 2007. Characterization of the novel H2N3 influenza virus subtype isolated from U.S. pigs [abstract]. American Association of Veterinary Laboratory Diagnosticians 50th Annual Conference. p. 123.Isolation of reassortant H2N3 avian/swine influenza virus from pigs in the United States

- (Abstract Only)Gramer, M., Goyal, S., Patnayak, D., Lager, K., Ma, W., Vincent, A., Richt, J., Webby, R. 2007. Isolation of reassortant H2N3 avian/swine influenza virus from pigs in the United States [abstract]. American Association of Veterinary Laboratory Diagnosticians 50th Annual Conference. p. 122.Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine

- (Peer Reviewed Journal)Vincent, A.L., Lager, K.M., Janke, B.H., Gramer, M.R., Richt, J.R. 2008. Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine. Veterinary Microbiology. 126(4):310-323.Comparison of the pathogenicity of  porcine circovirus type 2 group 1 and group 2 isolates

- (Proceedings)Cheung, A.K., Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T. 2007. Comparison of the pathogenicity of porcine circovirus type 2 group 1 and group 2 isolates. In: Proceedings of the 5th International Symposium on Emerging and Re-Emerging Pig Diseases, June 24-27, 2007, Krakow, Poland. p. 273.Mortality in pigs given PCV2 virus derived from DNA clones

- (Peer Reviewed Journal)Lager, K.M., Gauger, P.C., Vincent, A.L., Opriessnig, T., Kehrli, Jr., M.E., Cheung, A.K. 2007. Mortality in pigs given porcine circovirus type 2 subgroup 1 and 2 viruses derived from DNA clones. Veterinary Record. 161(12):428-429.Quantification of PCV2 capsid transcript in peripheral blood mononuclear cells (PBMCs) in vitro

- (Peer Reviewed Journal)Yu, S., Vincent, A., Opriessnig, T., Carpenter, S., Kitikoon, P., Halbur, P.G., Thacker, E. 2007. Quantification of PCV2 capsid transcript in peripheral blood mononuclear cells (PBMCs) in vitro. Veterinary Microbiology. 123:34-42.Coinfection with Swine Influenza Virus and Bordetella bronchiseptica in Pigs

- (Abstract Only)Brockmeier, S., Vincent, A.L., Sacco, R.E., Nicholson, T.L., Palmer, M.V. 2007. Coinfection with Swine Influenza Virus and Bordetella bronchiseptica in Pigs [abstract]. American Society for Microbiology Meeting, May 21-25,2007, Toronto, Canada. 2007 CD-ROM.PCVAD diagnosis and emerging diseases: building a systematic approach

- (Proceedings)Lager, K.M., Gauger, P.C., Vincent, A.L., Cheung, A.K. 2007. PCVAD diagnosis and emerging diseases: building a systematic approach. In: Proceedings of the American Association of Swine Veterinarians Annual Meeting, March 3-6, 2007, Orlando, Florida. p. 525-528.Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States

- (Abstract Only)Cheung, A.K., Lager, K.M., Vincent, A.L. 2006. Identification of two genotype subgroups of porcine circovirus type 2 in swine herds of the United States [abstract]. Conference of Research Workers in Animal Diseases 87th Annual Meeting. Paper No. 171. p. 78.The selected B cell population in PRRS has a naive phenotype, undiversified repertoire and unusually hydrophobic HCDR3

- (Abstract Only)Butler, J.E., Weber, P., Lemke, C.D., Kimura, K., Sinkora, M., Vincent, A.L., Vorwald, A.C., Lager, K.M. 2006. The selected B cell population in PRRS has a naive phenotype, undiversified repertoire and unusually hydrophobic HCDR3 [abstract]. 2006 International PRRS Symposium. Paper No. 33.Detection of two porcine circovirus type 2 genotypic groups in United States swine herds

- (Peer Reviewed Journal)Cheung, A.K., Lager, K.M., Kohutyuk, O.I., Vincent, A.L., Henry, S.C., Baker, R.B., Rowland, R.R., Dunham, A.G. 2007. Detection of two porcine circovirus type 2 genotypic groups in United States swine herds. Archives of Virology. 152(5):1035-1044.Diagnostics of Severe PCVAD

- (Proceedings)Lager, K.M., Vincent, A.L., Cheung, A.K., Gauger, P.C. 2006. Diagnostics of severe PCVAD. In: Proceedings of the 14th Annual Swine Disease conference for Practitioners, November 9-10, 2006, Ames, Iowa. p. 131-133.Analysis of activated immune cell populations in the bronchoalveolar lavage fluid of pigs immunized and/or infected with SIV

- (Abstract Only)Kimura, K., Vincent, A.L., Richt, J.A., Lager, K.M., Roth, J.A., Kehrli, Jr., M.E. 2006. Effect of vaccination and/or challenge of swine influenza virus on the proportion of activated cells in bronchoalveolar lavage fluid [abstract]. Great Lakes International Imaging and Flow Cytometry Association. Paper No. 7.Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine

- (Peer Reviewed Journal)Richt, J.A, Lekcharoensuk, P., Lager, K.M., Vincent, A.L., Loiacono, C.M., Janke, B.H., Wu, W.H., Yoon, K.J., Webby, R.J., Solorzano, A., Garcia-Sastre, A. 2006. Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine. Journal of Virology. 80(22):11009-11018.EVALUATION OF HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA VIRUSES FROM THE UNITED STATES

- (Peer Reviewed Journal)Vincent, A.L., Lager, K.M., Ma, W., Lekcharoensuk, P., Gramer, M.R., Loiacono, C., Richt, J.A. 2006. Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States. Veterinary Microbiology. 118(3-4):212-222.INFLUENZA VACCINE RESEARCH AT THE NATIONAL ANIMAL DISEASE CENTER

- (Proceedings)VACCINATION OF PIGS AGAINST SWINE INFLUENZA VIRUSES USING A NS1-DELETED MODIFIED LIVE VACCINE

- (Abstract Only)Richt, J.A., Lekcharoensuk, P., Lager, K.M., Vincent, A.L., Ma, W., Loiacono, C.M., Wu, W.H., Webby, R.J., Solorzano, A., Garcia-Sastre, A. 2006. Vaccination of pigs against swine influenza viruses using a NS1-deleted modified live vaccine [abstract]. 13th International Conference on Negative Strand Viruses. Paper No. 277. p. 198.FAILURE OF CROSS-PROTECTION BY INACTIVATED VACCINES FOR TWO U.S. H1 SWINE INFLUENZA VIRUS (SIV) ISOLATES

- (Proceedings)Vincent, A.L., Lager, K.M., Gramer, M.G., Richt, J.A., Janke, B.H. 2006. Failure of cross-protection by inactivated vaccines for two U.S.  H1 swine influenza virus (SIV) isolates. In: Proceedings of the 19th International Pig Veterinary Society Congress, July 16-19, 2006, Copenhagen, Denmark. p. 266.ASSAY FOR PROLIFERATION OF PORCINE PBMC WITH OREGON GREEN 488 AND ITS APPLICATION FOR EVALUATION OF T CELL RESPONSIVENESS TO SWINE INFLUENZA VIRUS

- (Abstract Only)Kimura, K., Vincent, A.L., Lager, K.M., Roth, J.A., Kehrli, Jr., M.E. 2006. Assay for proliferation of porcine PBMC with Oregon Green 488 and its application for evaluation of T cell responsiveness to swine influenza virus [astract]. Journal of Immunology Supplement. 176:S118. Paper No. 59.12.NOVEL SWINE INFLUENZA VIRUS SUBTYPE H3N1, UNITED STATES

- (Peer Reviewed Journal)Lekcharoensuk, P., Lager, K.M., Vemulapalli, R., Woodruff, M., Vincent, A.L., Richt, J.A. 2006. Novel swine influenza virus subtype H3N1, United States. Emerging Infectious Diseases. 12(5):787-794.ACUTE BVDV INFECTIONS IN NON BOVINE SPECIES

- (Abstract Only)Ridpath, J.F., Lager, K.M., Vincent, A.L., Neill, J.D., Chase, C.L., Mark, C.S. 2006. Acute BVDV infections in non-bovine species. BVDV 2006 Symposium, National Cattlemens Beef Association Annual Meeting. Paper No. 19. p. 37.EVALUATION OF NORTH AMERICAN HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA ISOLATES

- (Proceedings)Vincent, A.L., Lekcharoensuk, P., Ma, W., Gramer, M., Richt, J.A., Lager, K.M. 2005. Evaluation of North American hemagglutinin subtype 1 swine influenza isolates. 40th United States-Japan Cooperative Program in Natural Resources Panel of Animal and Avian Health Meeting. p. 7.SEROLOGIC AND PATHOGENIC EVALUATION OF NORTH AMERICAN HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA ISOLATES

- (Proceedings)Vincent, A.L., Lekcharoensuk, P., Ma, W., Gramer, M., Richt, J.A., Lager, K.M. 2006. Serologic and pathogenic evaluation of North American hemagglutinin subtype 1 swine influenza isolates. In: Proceedings of the American Association of Swine Veterinarians 2006 Annual Meeting, March 5-7, 2006, Kansas City, Missouri. p. 467-470.AN INVESTIGATION OF SUSCEPTIBILITY TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BETWEEN TWO GENETICALLY DIVERSE COMMERCIAL LINES OF PIGS

- (Peer Reviewed Journal)Vincent, A.L., Thacker, B.J., Halbur, P.G., Rothschild, M.F., Thacker, E.L. 2006. An investigation of susceptibility to porcine reproductive and respiratory syndrome virus between two genetically diverse commercial lines of pigs. Journal of Animal Science. 84(1):49-57.ESTABLISHMENT OF A PIG MODEL FOR THE 1930 H1N1 SWINE INFLUENZA VIRUS AND APPLICATION OF REVERSE GENETICS

- (Abstract Only)Lekcharoensuk, P., Vincent, A.L., Lager, K.M., Solorzano, A., Garcia-Sastre, A., Richt, J.A. 2005. Establishment of a pig model for the 1930 H1N1 swine influenza virus and application of reverse genetics [abstract]. International Congress of Virology. p. 42.EVALUATION OF NORTH AMERICAN HEMAGGLUTININ SUBTYPE 1 SWINE INFLUENZA ISOLATES

- (Abstract Only)Vincent, A.L., Lekcharoensuk, P., Ma, W., Gramer, M., Richt, J.A., Lager, K.M. 2005. Evaluation of North American hemagglutinin subtype 1 swine influenza isolates [abstract]. International Congress of Virology. p. 44.THE IN VITRO SUSCEPTIBILITY OF MACROPHAGES TO PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS VARIES BETWEEN GENETICALLY DIVERSE LINES OF PIGS

- (Peer Reviewed Journal)Vincent, A.L., Thacker, B.J., Halbur, P.G., Rothschild, M.F., Thacker, E.L. 2005. The in vitro susceptibility of macrophages to porcine reproductive and respiratory syndrome virus varies between genetically diverse lines of pigs. Viral Immunology. 18:506-512.
                    ARS News Articles
                            item
                                                USDA's Agricultural Research Service Honors Scientists of the Yearitem
                                                USDA's Agricultural Research Service Announces Scientist of the Year and Other Awards


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov