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                    U.S. DEPARTMENT OF AGRICULTURE
 Endemic Poultry Viral Diseases Research: Athens, GA
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                        Richard B Russell Center
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ARS Home Southeast Area Athens, Georgia U.S. National Poultry Research Center Endemic Poultry Viral Diseases Research People & Locations







Steven  Conrad
                        Endemic Poultry Viral Diseases Research

                        




                        
                        Biologist
                        Phone: (706) 546-3134
                        
                        
                        Fax: (Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsSystems Biology Approaches to Develop Medical Countermeasures to Detect, Prevent, and Control Poultry Production Viral Diseases
                                                    In-House Appropriated
                                                                    (D)Accession Number: 441471Elucidate Host-Pathogen Interactions of Polymicrobial Infections in Broiler Chicken Production
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 444438Develop Novel Vaccines Against Avian Reovirus and to Elucidate Mechanisms of Viral Pathogenesis
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 444938**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Construction of recombinant Marek’s disease virus vaccine expressing sigma C proteins of avian reoviruses

- (Abstract Only)Whole genomic constellation of avian reovirus strains isolated from broilers with arthritis in North Carolina, USA
                                                        

- (Peer Reviewed Journal)Nour, I., Alvarez Narvaez, S., Harrell, T.L., Conrad, S.J., Mohanty, S.K. 2023. Whole genomic constellation of avian reovirus strains isolated from broilers with arthritis in North Carolina, USA. Viruses. 15:2191. https://doi.org/10.3390/v15112191.Toll-like receptor ligands enhance vaccine efficacy against a virulent Newcastle disease virus challenge in chickens
                                                        

- (Peer Reviewed Journal)Lee, C.W., Bakre, A.A., Olivier, T.L., Alvarez Narvaez, S., Harrell, T.L., Conrad, S.J. 2023. Toll-like receptor ligands enhance vaccine efficacy against a virulent Newcastle disease virus challenge in chickens. Pathogens. 12(10):1230. https://doi.org/10.3390/pathogens12101230.Optimizing the conditions for whole-genome sequencing of avian reoviruses
                                                        

- (Peer Reviewed Journal)Alvarez Narvaez, S., Harrell, T.L., Oluwayinka, O., Sellers, H.S., Khalid, Z., Hauck, R., Chowdhury, E.U., Conrad, S.J. 2023. Optimizing the conditions for whole-genome sequencing of avian reoviruses. Viruses. 15(9):1938. https://doi.org/10.3390/v15091938.Targeted ablation of exon 2 of the Avian Leukosis Virus-A (ALV-A)receptor gene in a chicken fibroblast cell line by CRISPR abrogates ALV-A infection
                                                        

- (Peer Reviewed Journal)Conrad, S.J., Mays, J.K., Hearn, C.J., Dunn, J.R. 2023. Targeted ablation of exon 2 of the Avian Leukosis Virus-A (ALV-A)receptor gene in a chicken fibroblast cell line by CRISPR abrogates ALV-A infection. Avian Diseases. 67(1):102-107. https://doi.org/10.1637/aviandiseases-D-22-00072.Identification and validation of Ikaros (IKZF1) as a cancer driver gene for Marek’s disease virus-induced lymphomas
                                                        

- (Peer Reviewed Journal)Steep, A., Hildebrandt, E.C., Xu, H., Hearn, C.J., Frishman, D., Niikura, M., Dunn, J.R., Kim, T.N., Conrad, S.J., Muir, W.M., Cheng, H.H. 2022. Identification and validation of Ikaros (IKZF1) as a cancer driver gene for Marek’s disease virus-induced lymphomas. Microorganisms. 10(2):401. https://doi.org/10.3390/microorganisms10020401.Deletion of the viral thymidine kinase in a meq-deleted recombinant Marek's disease virus reduces lymphoid atrophy but is less protective
                                                        

- (Peer Reviewed Journal)Conrad, S.J., Oluwayinka, E.B., Mays, J.K., Heidari, M., Dunn, J.R. 2021. Deletion of the viral thymidine kinase in a meq-deleted recombinant Marek's disease virus reduces lymphoid atrophy but is less protective. Microorganisms. 10(1):7. https://doi.org/10.3390/microorganisms10010007.Deletion of thymidine kinase reduces protection of Marek’s disease vaccine candidate

- (Abstract Only)Dunn, J.R., Conrad, S.J., Oluwayinka, E., Mays, J.K., Heidari, M. 2021. Deletion of thymidine kinase reduces protection of Marek’s disease vaccine candidate. American Association of Avian Pathologists. Deletion of thymidine kinase reduces protection of Marek's disease vaccine candidate [abstract].The Secretion of Type I Interferons as a Primary Determinant of Susceptibility to Marek’s Disease Virus in Chickens

- (Abstract Only)Codon deoptimization of UL54 in meq-deleted Marek's disease vaccine candidate eliminates lymphoid atrophy but reduces vaccinal protection
                                                        

- (Peer Reviewed Journal)Conrad, S.J., Hearn, C.J., Silva, R.F., Dunn, J.R. 2020. Codon deoptimization of UL54 in meq-deleted Marek's disease vaccine candidate eliminates lymphoid atrophy but reduces vaccinal protection. Avian Diseases. 64(3):243-246. https://doi.org/10.1637/aviandiseases-D-19-00166.


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