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                    U.S. DEPARTMENT OF AGRICULTURE
 Animal Genomics and Improvement Laboratory: Beltsville, MD
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ARS Home Northeast Area Beltsville, Maryland (BARC) Beltsville Agricultural Research Center Animal Genomics and Improvement Laboratory People & Locations







Daniel  Null
                        Animal Genomics and Improvement Laboratory

                        




                        
                        Animal Scientist
                        Phone: (301) 504-5068
                        
                        
                        Fax: (301) 504-8092(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            **Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Improved tracking of recent mutations within common haplotypes causing cholesterol deficiency, muscle weakness, and BLIRD

- (Abstract Only)New mutation within a common haplotype is associated with calf muscle weakness in Holsteins
                                                        

- (Peer Reviewed Journal)Al-Khudhair, A.S., Van Raden, P.M., Null, D.J., Neupane, M., Mcclure, M.C., Dechow, C.D. 2024. New mutation within a common haplotype is associated with calf muscle weakness in Holsteins. Journal of Dairy Science. 107(6):3768-3779. https://doi.org/10.3168/jds.2023-24121.Inheritance of a new mutation affecting muscle weakness within a common haplotype in Holsteins

- (Proceedings)Al-Khudhair, A.S., Nicolazzi, E.L., Van Raden, P.M., Null, D.J., Neupane, M., Dechow, C.D. 2023. Inheritance of a new mutation affecting muscle weakness within a common haplotype in Holsteins. Interbull Bulletin. 59:202-206.Identification of candidate lethal haplotypes and genomic association with post-natal mortality and reproductive traits in Nellore cattle
                                                        

- (Peer Reviewed Journal)Schmidt, P., Mota, L., Fonseca, L., Dos Santos Silva, D., Frezzarim, G., Arikawa, L., De Abreu Santos, D., Magalhaes, A., Cole, J., Carvalheiro, R., De Oliveira, H., Null, D.J., Van Raden, P.M., Ma, L., De Albuquerque, L. 2023. Identification of candidate lethal haplotypes and genomic association with post-natal mortality and reproductive traits in Nellore cattle. Scientific Reports. 13:10399. https://doi.org/10.1038/s41598-023-37586-z.Haplotype inheritance and livability of recumbent Holstein calves

- (Abstract Only)Al-Khudhair, A.S., Van Raden, P.M., Null, D.J., Neupane, M., Dechow, C.D. 2023. Haplotype inheritance and livability of recumbent Holstein calves [abstract]. Journal of Dairy Science. 106(Suppl. 1):321(abstr. 1348T).Candidate mutation for calf recumbency in Holsteins

- (Abstract Only)Dechow, C., VanRaden, P.M., Null, D.J., Al-Khudhair, A.S., McClure, M. 2023. Candidate mutation for calf recumbency in Holsteins [abstract]. Journal of Dairy Science. 106(Suppl. 1):52-53(abstr. 2245).Adding and reporting genomically discovered ancestors in US evaluations

- (Proceedings)Carrillo, J., Van Raden, P.M., Ogwo, E.O., Mota, R.R., Wiggans, G.R., Bacheller, L.R., Fok, G.C., Null, D.J. 2022. Adding and reporting genomically discovered ancestors in US evaluations. Interbull Bulletin. 57:23-27.Truncation of IFT80 causes early embryonic loss in Holstein cattle associated with Holstein haplotype 2
                                                        

- (Peer Reviewed Journal)Ortega, M.S., Bickhart, D.M., Lockhart, K.N., Null, D.J., Hutchison, J.L., McClure, J.C., Cole, J.B. 2022. Truncation of IFT80 causes early embryonic loss in Holstein cattle associated with Holstein haplotype 2. Journal of Dairy Science. 105(11):9001-9011. https://doi.org/10.3168/jds.2022-21853.Improved, expanded, and automated ancestor discovery

- (Abstract Only)Null, D.J., Wiggans, G.R., Ogwo, E.O., Van Raden, P.M. 2022. Improved, expanded, and automated ancestor discovery [abstract]. Journal of Dairy Science. 105(Suppl. 1):389(abstr. 2422V).Evidence of selection against recessive defects

- (Abstract Only)Norman, H.D., Null, D.J., Van Raden, P.M. 2022. Evidence of selection against recessive defects [abstract]. Journal of Dairy Science. 105(Suppl. 1):47(abstr. 1124).Recent advances and future needs in genotype imputation
                                                        

- (Proceedings)Van Raden, P.M., Null, D.J., Al-Khudhair, A.S. 2022. Recent advances and future needs in genotype imputation. World Congress of Genetics Applied in Livestock Production. Front Matter, Commun. 349, pp. 1463-1466. https://doi.org/10.3920/978-90-8686-940-4_349.Inheritance of a mutation causing neuropathy with splayed forelimbs in Jersey cattle
                                                        

- (Peer Reviewed Journal)Al-Khudhair, A.S., Null, D.J., Cole, J.B., Wolfe, C.W., Steffen, D.J., Van Raden, P.M. 2022. Inheritance of a mutation causing neuropathy with splayed forelimbs in Jersey cattle. Journal of Dairy Science. 105(2):1338–1345. https://doi.org/10.3168/jds.2021-20600.Genomic evaluation of crossbred dairy cattle in the United States – an update

- (Proceedings)Wiggans, G.R., Van Raden, P.M., Null, D.J., Nicolazzi, E., Jansen, G.B., Megonigal, Jr., J.H. 2021. Genomic evaluation of crossbred dairy cattle in the United States – an update. Interbull Bulletin. 56:17–21.Inheritance of a mutation causing neuropathy with splayed forelimbs in Jersey cattle

- (Abstract Only)Al-Khudhair, A.S., Null, D.J., Cole, J.B., Wolfe, C.W., Van Raden, P.M. 2021. Inheritance of a mutation causing neuropathy with splayed forelimbs in Jersey cattle [abstract]. Journal of Dairy Science. 104(Suppl. 1):77–78(abstr. 199).Genomic evaluation of crossbred dairy cattle in the United States

- (Abstract Only)Development of polymorphic markers in the immune gene complex loci of cattle
                                                        

- (Peer Reviewed Journal)Bakshy, K., Heimeier, D., Schwartz, J.C., Glass, E.J., Wilkinson, S., Skuce, R.A., Allen, A.R., Young, J., McClure, J.C., Cole, J.B., Null, D.J., Hammond, J.A., Smith, T.P.L., Bickhart, D.M. 2021. Development of polymorphic markers in the immune gene complex loci of cattle. Journal of Dairy Science. 104(6):6897-6908. https://doi.org/10.3168/jds.2020-19809.Haplotype tests for economically important traits of dairy cattle

- (Government Publication)Cole, J.B., Van Raden, P.M., Null, D.J., Hutchison, J.L., Hubbard, S.M. 2020. Haplotype tests for economically important traits of dairy cattle. AIP Research Report. GENOMICS5 (12-20).Marker selection and genomic prediction of economically important traits multiple traits using imputed high-density genotypes for 5 breeds of dairy cattle

- (Peer Reviewed Journal)Major quantitative trait loci influencing milk production and conformation traits in Guernsey dairy cattle detected on Bos taurus autosome 19
                                                        

- (Peer Reviewed Journal)Li, B., Van Raden, P.M., Null, D.J., O'Connell, J.R., Cole, J.B. 2021. Major quantitative trait loci influencing milk production and conformation traits in Guernsey dairy cattle detected on Bos taurus autosome 19. Journal of Dairy Science. 104(1):550–560. https://doi.org/10.3168/jds.2020-18766.Haplotype- and sequence-based identification of a deletion associated with early embryonic loss in Holstein cattle and functional validation using CRISPR-Cas9 knockouts

- (Abstract Only)Genomic prediction of residual feed intake in US Holstein dairy cattle
                                                        

- (Peer Reviewed Journal)Li, B., Van Raden, P.M., Guduk, E., O'Connell, J.R., Null, D.J., Connor, E.E., VandeHaar, M.J., Tempelman, R.J., Weigel, K.A., Cole, J.B. 2020. Genomic prediction of residual feed intake in US Holstein dairy cattle. Journal of Dairy Science. 103(3):2477-2486. https://doi.org/10.3168/jds.2019-17332.Using the ARS-UCD1.2 reference genome in U.S. evaluations

- (Proceedings)Null, D.J., Van Raden, P.M., Rosen, B.D., O'Connell, J.R., Bickhart, D.M. 2019. Using the ARS-UCD1.2 reference genome in U.S. evaluations. Interbull Bulletin. 55:30-34.Enhancements to U.S. genetic and genomic evaluations in 2018 and 2019

- (Proceedings)Nicolazzi, E., Bacheller, L.R., Fok, G.C., Parker Gaddis, K.L., Jensen, L., Megonigal, Jr, J.H., Norman, H.D., Null, D.J., Walton, L.M., Wiggans, G.R., Cole, J.B., Durr, J.W., Van Raden, P.M. 2019. Enhancements to U.S. genetic and genomic evaluations in 2018 and 2019. Interbull Bulletin. 55:26-29.High-density genome-wide association study for residual feed intake in Holstein dairy cattle
                                                        

- (Peer Reviewed Journal)Li, B., Fang, L., Null, D.J., Hutchison, J.L., Connor, E.E., Van Raden, P.M., Cole, J.B. 2019. High-density genome-wide association study for residual feed intake in Holstein dairy cattle. Journal of Dairy Science. 102(12):11067-11080. https://doi.org/10.3168/jds.2019-16645.Integrating signals from sperm methylome analysis and genome-wide association study for a better understanding of male fertility in cattle
                                                        

- (Peer Reviewed Journal)Fang, L., Zhou, Y., Liu, S., Jiang, J., Bickhart, D.M., Null, D.J., Li, B., Schroeder, S.G., Rosen, B.D., Cole, J.B., Van Tassell, C.P., Ma, L., Liu, G. 2019. Integrating signals from sperm methylome analysis and genome-wide association study for a better understanding of male fertility in cattle. Epigenomes. 3(2):10. https://doi.org/10.3390/epigenomes3020010.Short communication: Phenotypic and genetic effects of the polled haplotype on yield, longevity, and fertility in US Brown Swiss, Holstein, and Jersey cattle
                                                        

- (Peer Reviewed Journal)Cole, J.B., Null, D.J. 2019. Short communication: Phenotypic and genetic effects of the polled haplotype on yield, longevity, and fertility in US Brown Swiss, Holstein, and Jersey cattle. Journal of Dairy Science. 102(9):8247–8250. https://doi.org/10.3168/jds.2019-16530.Genomic prediction and marker selection using high-density genotypes from 5 dairy breeds

- (Abstract Only)Van Raden, P.M., Null, D.J., O'Connell, J.R., Cole, J.B., Li, B. 2019. Genomic prediction and marker selection using high-density genotypes from 5 dairy breeds . Journal of Dairy Science. 102(Suppl. 1):400(abstr. 471).Genomic predictions using more markers and gene tests

- (Abstract Only)Wiggans, G.R., Van Raden, P.M., Null, D.J., Cole, J.B. 2019. Genomic predictions using more markers and gene tests. Journal of Dairy Science. 102(Suppl. 1):397(abstr. 462).Comparative analyses of sperm DNA methylomes among human, mouse and cattle provide insights into epigenomic evolution and complex traits
                                                        

- (Peer Reviewed Journal)Fang, L., Zhou, Y., Liu, S., Jiang, J., Bickhart, D.M., Null, D.J., Li, B., Schroeder, S.G., Rosen, B.D., Cole, J.B., Van Tassell, C.P., Ma, L., Liu, G. 2019. Comparative analyses of sperm DNA methylomes among human, mouse and cattle provide insights into epigenomic evolution and complex traits. Epigenetics. 14(3):260-276. https://doi.org/10.1080/15592294.2019.1582217.Haplotype tests for economically important traits of dairy cattle

- (Government Publication)Van Raden, P.M., Cole, J.B., Null, D.J., Hutchison, J.L., Hubbard, S.M. 2018. Haplotype tests for economically important traits of dairy cattle. AIPL Research Reports. GENOMIC4 (12-18).Genetic and nongenetic profiling of milk pregnancy-associated glycoproteins in Holstein cattle
                                                        

- (Peer Reviewed Journal)Santos, D.A., Cole, J.B., Null, D.J., Byrem, T.M., Ma, L. 2018. Genetic and nongenetic profiling of milk pregnancy-associated glycoproteins in Holstein cattle. Journal of Dairy Science. 101(11):9987-10000. https://doi.org/10.3168/jds.2018-14682.Identification of genomic regions associated with resistance to clinical mastitis in US Holstein cattle

- (Abstract Only)Identification of genomic regions associated with resistance to clinical mastitis in US Holstein cattle

- (Abstract Only)Cole, J.B., Parker Gaddis, K.L., Willard, C., Null, D.J., Maltecca, C., Clay, J.S. 2018. Identification of genomic regions associated with resistance to clinical mastitis in US Holstein cattle. Journal of Dairy Science. 101(Suppl. 2):138(abstr. 58).Potential benefits from using a new reference map in genomic prediction

- (Abstract Only)Null, D.J., Van Raden, P.M., Bickhart, D.M., Cole, J.B., O'Connell, J.R., Rosen, B.D. 2018. Potential benefits from using a new reference map in genomic prediction. Journal of Dairy Science. 101 (Suppl. 2):181-182(abstr. 168).Convergent evolution of slick coat in cattle through truncation mutations in the prolactin receptor
                                                        

- (Peer Reviewed Journal)Porto-Neto, L.R., Bickhart, D.M., Landaeta-Hernandez, A.J., Utsunomiya, Y.T., Morales, M.P., Caban-Jimenez, E., Hansen, P.J., Dikmen, S., Schroeder, S.G., Sun, J., Crespo, E., Amati, N., Cole, J.B., Null, D.J., Garcia, J.F., Reverter, A., Barendse, W., Sonstegard, T.S. 2018. Convergent evolution of slick coat in cattle through truncation mutations in the prolactin receptor. Frontiers in Genetics. 9:57. https://doi.org/10.3389/fgene.2018.00057Genome-wide association study and gene network analysis of fertility, retained placenta, and metritis in US Holstein cattle

- (Proceedings)Cole, J.B., Parker Gaddis, K.L., Null, D.J., Maltecca, C., Clay, J.S. 2018. Genome-wide association study and gene network analysis of fertility, retained placenta, and metritis in US Holstein cattle. World Congress of Genetics Applied in Livestock Production. Auckland, New Zealand, Feb. 11–16, Vol. Biol.–Dis. Resist. 1, p. 171.Genomic evaluation of age at first calving
                                                        

- (Peer Reviewed Journal)Hutchison, J.L., Van Raden, P.M., Null, D.J., Cole, J.B., Bickhart, D.M. 2017. Genomic evaluation of age at first calving. Journal of Dairy Science. 100(8):6853-6861. https://doi.org/10.3168/jds.2016-12060.Discovery of a haplotype affecting fertility in Ayrshire dairy dattle and identification of a putative causal variant

- (Abstract Only)Null, D.J., Hutchison, J.L., Bickhart, D.M., Van Raden, P.M., Cole, J.B. 2017. Discovery of a haplotype affecting fertility in Ayrshire dairy dattle and identification of a putative causal variant. Journal of Dairy Science. 100(Suppl. 2):199(abstr. 205).A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows

- (Peer Reviewed Journal)Ortega, M., Wohlgemuth, S., Tribulo, P., Siqueira, L.G., Null, D.J., Cole, J.B., Da Silva, M.V., Hansen, P.J. 2017. A single nucleotide polymorphism in COQ9 affects mitochondrial and ovarian function and fertility in Holstein cows. Biology of Reproduction. 96(3):652-663.The Larson Blue coat color phenotype in Holsteins: Characteristics and effects on body temperature regulation and production in lactating cows in a hot climate

- (Peer Reviewed Journal)Dikmen, S., Dahl, G.E., Cole, J.B., Null, D.J., Hansen, P.J. 2017. The Larson Blue coat color phenotype in Holsteins: Characteristics and effects on body temperature regulation and production in lactating cows in a hot climate. Journal of Animal Science. 95(3):1164-1169.Association of single nucleotide polymorphisms in candidate genes previously related to genetic variation in fertility with phenotypic measurements of reproductive function in Holstein cows

- (Peer Reviewed Journal)Ortega, M., Denicol, A.C., Cole, J.B., Null, D.J., Taylor, J.F., Schnabel, R.D., Hansen, P.J. 2017. Association of single nucleotide polymorphisms in candidate genes previously related to genetic variation in fertility with phenotypic measurements of reproductive function in Holstein cows. Journal of Dairy Science. 100(5):3725-3734.Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle
                                                        

- (Peer Reviewed Journal)Parker Gaddis, K.L., Dikmen, S., Null, D.J., Cole, J.B., Hansen, P.J. 2017. Evaluation of genetic components in traits related to superovulation, in vitro fertilization, and embryo transfer in Holstein cattle. Journal of Dairy Science. 100(4):2877-2891.Phenotypic and genetic effects of recessive haplotypes on yield, longevity, and fertility

- (Peer Reviewed Journal)Cole, J.B., Null, D.J., Van Raden, P.M. 2016. Phenotypic and genetic effects of recessive haplotypes on yield, longevity, and fertility. Journal of Dairy Science. 99(9):7274-7288.Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle

- (Peer Reviewed Journal)Adams, H.A., Sonstegard, T.S., Van Raden, P.M., Null, D.J., Van Tassell, C.P., Larkin, D.M., Lewin, H.A. 2016. Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle. Journal of Dairy Science. 99(8):6693-6701.Use of a threshold animal model to estimate calving ease and stillbirth (co)variance components for US Holsteins

- (Abstract Only)Cole, J.B., Null, D.J., Tsuruta, S. 2016. Use of a threshold animal model to estimate calving ease and stillbirth (co)variance components for US Holsteins. Journal of Dairy Science. 99(E-Suppl. 1)/Journal of Animal Science. 94(E-Suppl. 5):182-183(abstr. 0385).Genomic analysis of lactation persistency in four breeds of dairy cattle

- (Abstract Only)Cole, J.B., Null, D.J., Parker Gaddis, K.L. 2016. Genomic analysis of lactation persistency in four breeds of dairy cattle. Journal of Dairy Science. 99(E-Suppl. 1)/Journal of Animal Science. 94(E-Suppl. 5):156(abstr. 0333).Exploring the feasibility of using copy number variants as genetic markers through large-scale whole genome sequencing experiments

- (Abstract Only)Bickhart, D.M., Xu, L., Hutchison, J.L., Cole, J.B., Null, D.J., Schroeder, S.G., Song, J., Garcia, J.F., Sonstegardq, T.S., Van Tassell, C.P., Schnabel, R.D., Taylor, J.F., Lewin, H.A., Liu, G. 2016. Exploring the feasibility of using copy number variants as genetic markers through large-scale whole genome sequencing experiments. Journal of Dairy Science. 99(E-Suppl. 1)/Journal of Animal Science. 94(E-Suppl. 5):142(abstr. 0306).Explorations in genome-wide association studies and network analyses with dairy cattle fertility traits

- (Peer Reviewed Journal)Parker Gaddis, K.L., Null, D.J., Cole, J.B. 2016. Explorations in genome-wide association studies and network analyses with dairy cattle fertility traits. Journal of Dairy Science. 99(8):6420-6435.Diversity and population-genetic properties of copy number variations and multicopy genes in cattle

- (Abstract Only)Bickhart, D.M., Xu, L., Hutchison, J.L., Cole, J.B., Null, D.J., Schroeder, S.G., Song, J., Garcia, J., Van Tassell, C.P., Sonstegard, T.S., Schnabel, R.D., Taylor, J.F., Lewin, H.A., Liu, G. 2016. Diversity and population-genetic properties of copy number variations and multicopy genes in cattle [abstract]. USDA NIFA Animal Genome Program PD Meeting, January 8, 2016, San Diego, California.Use of single nucleotide polymorphisms in candidate genes associated with daughter pregnancy rate for prediction of genetic merit for reproduction in Holstein cows

- (Peer Reviewed Journal)Ortega, M., Denicol, A.C., Cole, J.B., Null, D.J., Hansen, P.J. 2016. Use of single nucleotide polymorphisms in candidate genes associated with daughter pregnancy rate for prediction of genetic merit for reproduction in Holstein cows. Animal Genetics. 47(3):288–297.Reducing animal sequencing redundancy by preferentially selecting animals with low-frequency haplotypes

- (Peer Reviewed Journal)Bickhart, D.M., Hutchison, J.L., Null, D.J., Van Raden, P.M., Cole, J.B. 2016. Reducing animal sequencing redundancy by preferentially selecting animals with low-frequency haplotypes. Journal of Dairy Science. 99(7):5526-5534.Cattle sex-specific recombination and genetic control from a very large pedigree

- (Peer Reviewed Journal)Ma, L., O'Connell, J.R., Van Raden, P.M., Shen, B., Padhi, A., Sun, C., Bickhart, D.M., Cole, J.B., Null, D.J., Liu, G., Da, Y., Wiggans, G.R. 2015. Cattle sex-specific recombination and genetic control from a very large pedigree. PLoS Genetics. 11(11):e1005387.Single nucleotide polymorphisms associated with thermoregulation in lactating dairy cows exposed to heat stress

- (Peer Reviewed Journal)Dikmen, S., Wang, X., Ortega, M., Null, D.J., Cole, J.B., Hansen, P.J. 2015. Single nucleotide polymorphisms associated with thermoregulation in lactating dairy cows exposed to heat stress. Journal of Animal Breeding and Genetics. 132(6):409-419.Assignment of polled status using single nucleotide polymorphism genotypes and predicted gene content

- (Abstract Only)Null, D.J., Cole, J.B., Sun, C., Van Raden, P.M. 2015. Assignment of polled status using single nucleotide polymorphism genotypes and predicted gene content. Journal of Dairy Science. 98(Suppl. 2)/Journal of Animal Science 93(Suppl. 3):800(abstr. 647).Single nucleotide polymorphisms in specific candidate genes are associated with phenotypic differences in days open for first lactation in Holstein cows

- (Abstract Only)Ortega, M., Denicol, A., Null, D.J., Cole, J.B., Hansen, P.J. 2015. Single nucleotide polymorphisms in specific candidate genes are associated with phenotypic differences in days open for first lactation in Holstein cows. Journal of Dairy Science. 98(Suppl. 2)/Journal of Animal Science 93(Suppl. 3):648–649(abstr. W85).Genetic base changes for December 2014

- (Government Publication)Van Raden, P.M., Tooker, M.E., Wright, J.R., Cole, J.B., Null, D.J., Lawlor, T.J. 2014. Genetic base changes for December 2014. AIP Research Report BASE3(10-14).Dissection of genomic correlation matrices of US Holsteins using multivariate factor analysis

- (Peer Reviewed Journal)Macciotta, N., Dimauro, C., Null, D.J., Gaspa, G., Castellini, M., Cole, J.B. 2015. Dissection of genomic correlation matrices of US Holsteins using multivariate factor analysis. Journal of Animal Breeding and Genetics. 132(1):9-20.The identification of a putative mutation for SLICK hair coat in Senepol cattle

- (Abstract Only)Increasing the number of single nucleotide polymorphisms used in genomic evaluations of dairy cattle

- (Proceedings)Wiggans, G.R., Cooper, T.A., Null, D.J., Van Raden, P.M. 2014. Increasing the number of single nucleotide polymorphisms used in genomic evaluations of dairy cattle. World Congress of Genetics Applied in Livestock Production. Vancouver, Canada, Aug. 17–22. 3 pp.Single nucleotide polymorphisms in candidate genes related to daughter pregnancy rate in Holstein cows

- (Proceedings)Ortega, M.S., Denicol, A.C., Null, D.J., Cole, J.B., Hansen, P.J. 2014. Single nucleotide polymorphisms in candidate genes related to daughter pregnancy rate in Holstein cows. World Congress of Genetics Applied in Livestock Production. Vancouver, Canada, Aug. 17–22. 2 pp.The hunt for a functional mutation affecting conformation and calving traits on chromosome 18 in Holstein cattle

- (Proceedings)Cole, J.B., Hutchison, J.L., Null, D.J., Van Raden, P.M., Liu, G., Schroeder, S.G., Smith, T.P., Sonstegard, T.S., Van Tassell, C.P., Bickhart, D.M. 2014. The hunt for a functional mutation affecting conformation and calving traits on chromosome 18 in Holstein cattle. World Congress of Genetics Applied in Livestock Production. Vancouver, Canada, Aug. 17–22. 3 pp.Using haplotypes to unravel the inheritance of Holstein coat color for a larger audience

- (Proceedings)Lawlor, T.J., Van Raden, P.M., Null, D.J., Levisee, J., Dorhorst, B. 2014. Using haplotypes to unravel the inheritance of Holstein coat color for a larger audience. World Congress of Genetics Applied in Livestock Production. Vancouver, Canada, Aug. 17–22. 3 pp.Genotypes are useful for more than genomic evaluation

- (Proceedings)Van Raden, P.M., Sun, C., Cooper, T.A., Null, D.J., Cole, J.B. 2014. Genotypes are useful for more than genomic evaluation. International Committee on Animal Recording(ICAR). Proc. 39th Int. Comm. Anim. Recording Sess., Berlin, Germany, May 19–23, 4 pp.Calculation and delivery of US genomic evaluations for dairy cattle

- (Abstract Only)Wiggans, G.R., Cooper, T.A., Van Raden, P.M., Null, D.J., Hutchison, J.L., Meland, O.M., Tooker, M.E., Norman, H.D. 2014. Calculation and delivery of US genomic evaluations for dairy cattle. Journal of Dairy Science. 97(E-Suppl. 1):77–78 (abstr. 0152).Bovine exome sequence analysis and targeted SNP genotyping of recessive fertility defects HH2, HH3, and BH1 reveals causative mutation in SMC2 for HH3
                                                        

- (Peer Reviewed Journal)Mc Clure, M., Bickhart, D.M., Null, D.J., Van Raden, P.M., Xu, L., Wiggans, G.R., Liu, G., Schroeder, S.G., Glasscock, J., Armstrong, J., Cole, J.B., Sonstegard, T.S., Van Tassell, C.P. 2014. Bovine exome sequence analysis and targeted SNP genotyping of recessive fertility defects HH2, HH3, and BH1 reveals causative mutation in SMC2 for HH3. PLoS One. 9(3):e92769.Genomic evaluation, breed identification, and discovery of a haplotype affecting fertility for Ayrshire dairy cattle
                                                        

- (Peer Reviewed Journal)Cooper, T.A., Wiggans, G.R., Null, D.J., Hutchison, J.L., Cole, J.B. 2014. Genomic evaluation, breed identification, and discovery of a haplotype affecting fertility for Ayrshire dairy cattle. Journal of Dairy Science. 97(6):3878-3882.Candidate causative mutation on BTA18 associated with calving and conformation traits in Holstein bulls

- (Abstract Only)Cole, J.B., Hutchison, J.L., Null, D.J., Van Raden, P.M., Liu, G., Schroeder, S.G., Sonstegard, T.S., Van Tassell, C.P., Bickhart, D.M. 2014. Candidate causative mutation on BTA18 associated with calving and conformation traits in Holstein bulls. Plant and Animal Genome Conference Proceedings. Plant Animal Genome XXII, San Diego, CA, Jan. 11–15, P1097.Haplotype tests for recessive disorders that affect fertility and other traits

- (Government Publication)Cole, J.B., Van Raden, P.M., Null, D.J., Hutchison, J.L., Cooper, T.A. 2013. Haplotype tests for recessive disorders that affect fertility and other traits. AIPL Research Reports. Genomics (09-13).Single nucleotide polymorphisms in candidate genes associated with fertilizing ability of sperm and subsequent embryonic development in cattle
                                                        

- (Peer Reviewed Journal)Cochran, S.D., Cole, J.B., Null, D.J., Hansen, P.J. 2013. Single nucleotide polymorphisms in candidate genes associated with fertilizing ability of sperm and subsequent embryonic development in cattle. Biology of Reproduction. 89(3):69.Genome-wide association mapping for identification of quantitative trait loci for rectal temperature during heat stress in Holstein cattle
                                                        

- (Peer Reviewed Journal)Dikmen, S., Cole, J.B., Null, D.J., Hansen, P.J. 2013. Genome-wide association mapping for identification of quantitative trait loci for rectal temperature during heat stress in Holstein cattle. PLoS One. 8(7):e69202.Discovery of single nucleotide polymorphisms in candidate genes associated with fertility and production traits in Holstein cattle
                                                        

- (Peer Reviewed Journal)Cochran, S.D., Cole, J.B., Null, D.J., Hansen, P.J. 2013. Discovery of single nucleotide polymorphisms in candidate genes associated with fertility and production traits in Holstein cattle. BioMed Central (BMC) Genetics. 14:49.Genomic evaluation and identification of haplotype affecting fertility for Ayrshire dairy cattle

- (Abstract Only)Cooper, T.A., Wiggans, G.R., Null, D.J., Hutchison, J.L. 2013. Genomic evaluation and identification of haplotype affecting fertility for Ayrshire dairy cattle. Journal of Dairy Science. 96(E-Suppl. 1):74 (abstr. T206).Optimal age at first calving for U.S. dairy cattle

- (Abstract Only)Cole, J.B., Hutchison, J.L., Bickhart, D.M., Null, D.J. 2013. Optimal age at first calving for U.S. dairy cattle. Journal of Dairy Science. 96(E-Suppl. 1):289–290 (abstr. W188).Dissection of genomic correlation matrices using multivariate factor analysis in dairy and dual-purpose cattle breeds

- (Abstract Only)Macciotta, N.P., Dimauro, C., Vicario, D., Cole, J.B., Null, D.J. 2013. Dissection of genomic correlation matrices using multivariate factor analysis in dairy and dual-purpose cattle breeds. Journal of Dairy Science. 96(E-Suppl. 1):618 (abstr. 541).Fine mapping for Weaver Syndrome in the Brown Swiss breed with the identification of possible casual mutations across NRCAM, PNPLA8, and CTTNBP2 and Developement of a diagnostic SNP haplotype

- (Peer Reviewed Journal)Mcclure, M.C., Kim, E., Bickhart, D.M., Null, D.J., Cooper, T.A., Cole, J.B., Wiggans, G.R., Marsan, P.A., Colli, L., Santus, E., Liu, G., Schroeder, S.G., Matukumalli, L., Van Tassell, C.P., Sonstegard, T.S. 2013. Fine mapping for Weaver Syndrome in the Brown Swiss breed with the identification of possible casual mutations across NRCAM, PNPLA8, and CTTNBP2 and Developement of a diagnostic SNP haplotype. PLoS One. 8(3):e59251.Visualization of the transmission of direct genomic values for paternal and maternal chromosomes for 15 traits in U.S. Brown Swiss, Holstein, and Jersey cattle

- (Peer Reviewed Journal)Cole, J.B., Null, D.J. 2013. Visualization of the transmission of direct genomic values for paternal and maternal chromosomes for 15 traits in US Brown Swiss, Holstein, and Jersey cattle. Journal of Dairy Science. 96(4):2713-2726.Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle

- (Peer Reviewed Journal)Sonstegard, T.S., Cole, J.B., Van Raden, P.M., Van Tassell, C.P., Null, D.J., Schroeder, S.G., Bickhart, D.M., Mcclure, M.C. 2013. Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle. PLoS One. 8(1):e54872.Genomic imputation and evaluation using high density Holstein genotypes

- (Peer Reviewed Journal)Van Raden, P.M., Null, D.J., Sargolzaei, M., Wiggans, G.R., Tooker, M.E., Cole, J.B., Sonstegard, T.S., Connor, E.E., Winters, M., Van Kaam, J., Van Doormaal, B.J., Faust, M.A., Doak, G.A. 2013. Genomic imputation and evaluation using high density Holstein genotypes. Journal of Dairy Science. 96(1):668-678.Fine mapping and discovery of recessive mutations that cause abortions in dairy cattle

- (Abstract Only)Van Raden, P.M., Null, D.J., Sonstegard, T.S., Adams, H.A., Van Tassell, C.P., Olson, K.M. 2012. Fine mapping and discovery of recessive mutations that cause abortions in dairy cattle. Journal of Dairy Science. 95(Suppl. 2):ii–iii(abstr. LB6). 2012.Reliability increases from combining 50,000- and 777,000-marker genotypes from four countries

- (Proceedings)Van Raden, P.M., Olson, K.M., Null, D.J., Sargolzaei, M., Winters, M., Van Kaam, J. 2012. Reliability increases from combining 50,000- and 777,000-marker genotypes from four countries. Interbull Annual Meeting Proceedings. Cork, Ireland, May 28–June 1, 4 pp.Short communication: Projecting milk yield using best prediction and the MilkBot lactation model

- (Peer Reviewed Journal)Cole, J.B., Ehrlich, J.L., Null, D.J. 2012. Short communication: Projecting milk yield using best prediction and the MilkBot lactation model. Journal of Dairy Science. 95(7):4041-4044.Genomic evaluation of rectal temperature in Holstein cattle

- (Abstract Only)Dikmen, S., Cole, J.B., Null, D.J., Hansen, P.J. 2012. Genomic evaluation of rectal temperature in Holstein cattle. Journal of Dairy Science. 95(Suppl. 2):401(abstr. 327). 2012.Heritability of rectal temperature and genetic correlations with production and reproduction traits in dairy cattle

- (Peer Reviewed Journal)Dikmen, S., Cole, J.B., Null, D.J., Hansen, P.J. 2012. Heritability of rectal temperature and genetic correlations with production and reproduction traits in dairy cattle. Journal of Dairy Science. 95(6):3401-3405.Harmful recessive effects on fertility detected by absence of homozygous haplotypes

- (Peer Reviewed Journal)Van Raden, P.M., Olson, K.M., Null, D.J., Hutchison, J.L. 2011. Harmful recessive effects on fertility detected by absence of homozygous haplotypes. Journal of Dairy Science. 94(12):6153-6161.Reporting of haplotypes with recessive effects on fertility

- (Proceedings)Van Raden, P.M., Null, D.J., Olson, K.M., Hutchison, J.L. 2011. Reporting of haplotypes with recessive effects on fertility. Interbull Annual Meeting Proceedings. Stavanger, Norway, Aug. 26–28, 4 pp.Genomic imputation and evaluation using 342 high density Holstein genotypes

- (Abstract Only)Van Raden, P.M., Null, D.J., Wiggans, G.R., Sonstegard, T.S., Connor, E.E. 2011. Genomic imputation and evaluation using 342 high density Holstein genotypes. Journal of Animal Science 89(E-Suppl. 1)/ Journal of Dairy Science 94(E-Suppl. 1):533(abstr. W53).Impacts of inclusion of foreign data in genomic evaluation of dairy cattle

- (Abstract Only)Olson, K.M., Van Raden, P.M., Null, D.J. 2011. Impacts of inclusion of foreign data in genomic evaluation of dairy cattle. Journal of Animal Science 89(E-Suppl. 1)/Journal of Dairy Science 94(E-Suppl. 1):164-65(abstr. 35).Heritability of rectal temperature and genetic correlations with production and reproduction traits in dairy cattle

- (Abstract Only)Dikmen, S., Cole, J.B., Null, D.J., Hansen, P.J. 2011. Heritability of rectal temperature and genetic correlations with production and reproduction traits in dairy cattle. Journal of Animal Science 89(E-Suppl. 1)/Journal of Dairy Science 94(E-Suppl. 1):255(abstr. 275).Short communication: Best prediction of 305-day lactation yields with regional and seasonal effects

- (Peer Reviewed Journal)Cole, J.B., Null, D.J., De Vries, A. 2011. Short communication: Best prediction of 305-day lactation yields with regional and seasonal effects. Journal of Dairy Science. 94(3):1601-1604.Age at First Calving in Holstein Cattle in the United States

- (Abstract Only)Cole, J.B., Null, D.J. 2010. Age at First Calving in Holstein Cattle in the United States. Journal of Dairy Science. 93(E-Suppl. 1):594(abstr. W28).Best prediction of lactation yields accounting for regional and seasonal differences

- (Abstract Only)Cole, J.B., Null, D.J. 2009. Best prediction of lactation yields accounting for regional and seasonal differences. Journal of Dairy Science. 92(E-Suppl. 1):209(abstr. T38).Genetic Evaluation of Lactation Persistency for Five Breeds of Dairy Cattle

- (Peer Reviewed Journal)Cole, J.B., Null, D.J. 2009. Genetic Evaluation of Lactation Persistency for Five Breeds of Dairy Cattle. Journal of Dairy Science. 92(5):2248-2258.Best Prediction of Yields for Long Lactations

- (Peer Reviewed Journal)Cole, J.B., Null, D.J., Van Raden, P.M. 2009. Best Prediction of Yields for Long Lactations. Journal of Dairy Science. 92(4):1796-1810.A data exchange format and national database for producer-recorded health event data from on-farm management software

- (Abstract Only)Cole, J.B., Null, D.J., Bacheller, L.R. 2008. A data exchange format and national database for producer-recorded health event data from on-farm management software. Journal of Dairy Science. 91(E-Suppl. 1):2–3(abstr. T6).


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