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                    U.S. DEPARTMENT OF AGRICULTURE
 Food Components and Health Laboratory: Beltsville, MD
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ARS Home Northeast Area Beltsville, Maryland (BHNRC) Beltsville Human Nutrition Research Center Food Components and Health Laboratory People & Locations







Janet  Novotny
                        Food Components and Health Laboratory

                        




                        
                        Research Physiologist
                        Phone: (301) 504-8263
                        
                        
                        Fax: (301) 504-9098(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
                            ProjectsFoodData Central
                                                    In-House Appropriated
                                                                    (D)Accession Number: 443340Strategies to Alter Dietary Food Components and Their Effects on Food Choice and Health-Related Outcomes  (BRIDGE)
                                                    In-House Appropriated
                                                                    (D)Accession Number: 445750Absorption, Distribution, Metabolism and Excretion of Food Components and their Impact on Chronic Disease Risk (BRIDGE)
                                                    In-House Appropriated
                                                                    (D)Accession Number: 446059Understanding Dietary Factors Affecting Colon and Liver Cancer Risk
                                                    Interagency Reimbursable Agreement
                                                                    (I)Accession Number: 444473The Impact of Sugar Reduction on Perception of Sweetness and Food Intake
                                                    Reimbursable Cooperative Agreement
                                                                    (R)Accession Number: 444238A Nutrimetabolomic Approach to Identify Biomarkers of Whole Grain Intake
                                                    Reimbursable Cooperative Agreement
                                                                    (R)Accession Number: 434906Effect of Minimally Processed Meat and Further Processed Meat on Biomarkers and Risk Factors for Cancer and Cardiovascular Disease - Phase 1
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 437882A Nutrimetabolomic Approach to Identify Biomarkers of Whole Grain Intake
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 437887Impact of Food and Particulates on Metabolic Risk
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 438888Absorption, Distribution, Metabolism and Excretion of Food Components and their Impact on Chronic Disease Risk
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 442299Vocabulary, Thesaurus and Ontology Development for USDA FoodData Central
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 443113Human Dietary Interventions to Reduce Risk of Chronic Diseases
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 444406Biological Effects of Particles Generated by Biodiesel Fuels and Wildfires
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 445096Glutathione, Mono- and Di-saccharides, Oligosaccharides in Foods
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 445142The Impact of Sugar Reduction on Perception of Sweetness and Food Intake
                                                    Non-Assistance Cooperative Agreement
                                                                    (S)Accession Number: 445287Effect of Minimally Processed Meat and Further Processed Meat on Biomarkers and Risk Factors for Cancer and Cardiovascular Disease - Phase 2
                                                    Trust Fund Cooperative Agreement
                                                                    (T)Accession Number: 444543Effect of Minimally Processed Meat and Further Processed Meat on Biomarkers and Risk Factors for Cancer and Cardiovascular Disease - Phase 1
                                                    Trust Fund Cooperative Agreement
                                                                    (T)Accession Number: 436100Data Pooling Project for Investigation Red Meat and Omnivorous Dietary Patterns, and Human Health via Metabolomics and Machine Learning Methods
                                                    Trust Fund Cooperative Agreement
                                                                    (T)Accession Number: 443730**Publications**
                                                (Clicking on the reprint icon
                                                    Reprint Icon
                                                    will take you to the publication reprint.)Separation of lipoproteins for quantitative analysis of 14C-labeled lipid soluble compounds by accelerator mass spectrometry
                                                        

- (Peer Reviewed Journal)Chuang, J.C., Clifford, A.J., Kim, S., Fadel, J.G., Novotny, J., Kelly, P.B., Holstege, D.M., Walzem, R.L. 2024. Separation of lipoproteins for quantitative analysis of 14C-labeled lipid soluble compounds by accelerator mass spectrometry. International Journal of Molecular Sciences. 25(3):1856. https://doi.org/10.3390/ijms25031856.Fecal metagenomics to identify biomarkers of food intake in healthy adults: findings from randomized, controlled, nutrition trials
                                                        

- (Peer Reviewed Journal)Shinn, L.M., Mansharamani, A., Baer, D.J., Novotny, J., Charron, C.S., Kahn, N.A., Zhu, R., Holscher, H.D. 2024. Fecal metagenomics to identify biomarkers of food intake in healthy adults: findings from randomized, controlled, nutrition trials. Journal of Nutrition. 154:271-283.Stability of carotenoids in sweet corn: Part 2. Effects of blanching, freezing, and canning
                                                        

- (Peer Reviewed Journal)Whent, M.M., Huang, J., Childs, H., Slavin, M., Harrison, D.J., Novotny Dura, J., Yu, L., Pehrsson, P.R., Wu, X. 2023. Stability of carotenoids in sweet corn: Part 2. Effects of blanching, freezing, and canning. ACS Food Science and Technology. 3(9):1590-1599. https://doi.org/10.1021/acsfoodscitech.3c00273.Mixed berry juice and cellulose fiber have differential effects on peripheral blood mononuclear cell respiration in overweight adults
                                                        

- (Peer Reviewed Journal)Solverson, P., Albaugh, G.P., Debelo, H., Ferruzzi, M.G., Baer, D.J., Novotny, J. 2023. Mixed berry juice and cellulose fiber have differential effects on peripheral blood mononuclear cell respiration in overweight adults. Nutrients. 15(7):1709-1724. https://doi.org/10.3390/nu15071709.Evaluation of postharvest handling and domestic cooking on carotenoids in sweet corn
                                                        

- (Peer Reviewed Journal)Whent, M.M., Huang, J., Childs, H., Slavin, M., Harrison, D.J., Novotny Dura, J., Yu, L., Pehrsson, P.R., Wu, X. 2023. Evaluation of postharvest handling and domestic cooking on carotenoids in sweet corn. Journal of Agricultural and Food Chemistry. 71:6133-6143. https://doi.org/10.1021/acs.jafc.3c00584.Impact of roasting on javamide-I/-II in Arabica and Robusta coffee beans
                                                        

- (Peer Reviewed Journal)Park, J.B., Peters, R.C., Novotny Dura, J. 2023. Impact of roasting on javamide-I/-II in Arabica and Robusta coffee beans. Food Chemistry. 412:135586. https://doi.org//10.1016/j.foodchem.2023.135586.Fecal metabolites as biomarkers for predicting food intake in healthy adults
                                                        

- (Peer Reviewed Journal)Shinn, L.A., Mansharamani, A., Baer, D.J., Novotny, J., Charron, C.S., Khan, N.A., Zhu, R., Holscher, H.D. 2022. Fecal metabolites as biomarkers for predicting food intake in healthy adults. Journal of Nutrition. 152:2956-2965. https://doi.org/10.1093/jn/nxac195.High-dose administration of purified cyanidin-3-glucose or a blackberry extract causes improved mitochondrial function but reduced content in 3T3-L1 adipocytes
                                                        

- (Peer Reviewed Journal)Solverson, P., Albaugh, G.P., Harrison, D.J., Luthria, D.L., Baer, D.J., Novotny, J. 2022. High-dose administration of purified cyanidin-3-glucose or a blackberry extract causes improved mitochondrial function but reduced content in 3T3-L1 adipocytes. Frontiers in Nutrition. 1-9. https://doi.org/10.1002/fft2.139.Vitamin D3 kinetics in nonpregnant and pregnant women after a single oral dose of trideuterated vitamin D3
                                                        

- (Peer Reviewed Journal)Best, C.M., Sherwood, R., Novotny, J.A., Zhang, S., Pressman, E.K., O’Brien, K.O. 2021. Vitamin D3 kinetics in nonpregnant and pregnant women after a single oral dose of trideuterated vitamin D3. The Journal of Steroid Biochemistry and Molecular Biology. 216:1-8. 106034. https://doi.org/10.1016/j.jsbmb.2021.106034.Study on human urinary metabolic profiles after consumption of kale and daikon radish using high-resolution mass spectrometry-based non-targeted and targeted metabolomic approach
                                                        

- (Peer Reviewed Journal)Sun, J., Charron, C.S., Zhihao, L., Novotny Dura, J., Harrington, P.B., Ross, S.A., Seifried, H.E., Chen, P. 2020. Study on human urinary metabolic profiles after consumption of kale and daikon radish using high-resolution mass spectrometry-based non-targeted and targeted metabolomic approach. Journal of Agricultural and Food Chemistry. 68:14307-14318. https://doi.org/10.1021/acs.jafc.0c05184.Fecal bacteria as biomarkers for predicting food intake in healthy adults
                                                        

- (Peer Reviewed Journal)Shinn, L.M., Li, Y., Mansharamani, A., Zhu, R., Auvil, L., Welge, M., Bushell, C., Khan, N.A., Charron, C.S., Novotny Dura, J., Baer, D.J., Holscher, H.D. 2020. Fecal bacteria as biomarkers for predicting food intake in healthy adults. Journal of Nutrition. https://doi.org/10.1093/jn/nxaa285.BMI is associated with increased plasma and urine appearance of glucosinolate metabolites after consumption of cooked broccoli
                                                        

- (Peer Reviewed Journal)Charron, C.S., Vinyard, B.T., Jeffery, E., Ross, S., Seifried, H., Novotny, J.A. 2020. BMI is associated with increased plasma and urine appearance of glucosinolate metabolites after consumption of cooked broccoli. Frontiers in Nutrition. https://doi.org/10.3389/fnut.2020.575092.An anthocyanin-rich mixed-berry intervention may improve insulin sensitivity in a randomized trial of overweight and obese adults
                                                        

- (Peer Reviewed Journal)Solverson, P.M., Henderson, T.R., Debelo, H., Ferruzzi, M.G., Baer, D.J., Novotny, J.A. 2019. An anthocyanin-rich mixed-berry intervention may improve insulin sensitivity in a randomized trial of overweight and obese adults. Nutrients. 11:2876. https://doi.org/10.3390/nu11122876.Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial
                                                        

- (Peer Reviewed Journal)Charron, C.S., Novotny, J.A., Jeffery, E., Kramer, M.H., Ross, S., Seifried, H. 2019. Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial. Journal of Functional Foods. 64:103624. https://doi.org/10.1016/j.jff.2019.103624.Profiling glucosinolate metabolites in human urine and plasma after broccoli consumption using non-targeted and targeted metabolomic analyses
                                                        

- (Peer Reviewed Journal)Sun, J., Charron, C.S., Novotny, J.A., Peng, B., Yu, L., Chen, P. 2019. Profiling glucosinolate metabolites in human urine and plasma after broccoli consumption using non-targeted and targeted metabolomic analyses. Food Chemistry. 309:125660. https://doi.org/10.1016/j.foodchem.2019.125660.Dietary intakes of flavan-3-ols and cardiometabolic health: systematic review and meta-analysis of randomized trials and prospective cohort studies
                                                        

- (Peer Reviewed Journal)Raman, G., Avendano, E., Chen, S., Wang, J., Matson, J., Gayer, B., Novotny, J.A., Cassidy, A. 2019. Dietary intakes of flavan-3-ols and cardiometabolic health: systematic review and meta-analysis of randomized trials and prospective cohort studies. American Journal of Clinical Nutrition. 110:1067-1078. https://doi.org/10.1093/ajcn/nqz178.Metabolizable energy from cashew nuts is less than that predicted by Atwater factors
                                                        

- (Peer Reviewed Journal)Baer, D.J., Novotny, J. 2018. Metabolizable energy from cashew nuts is less than that predicted by Atwater factors. Nutrients. 11:33. https://doi.org/10.3390/nu11010033.Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults
                                                        

- (Peer Reviewed Journal)Angiletta, C.J., Griffin, L.E., Steele, C.N., Baer, D.J., Novotny, J., Davy, K.P., Neilson, A.P. 2018. Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults. Food & Function. 9:5350-5361. https://doi.org/10.1039/C8FO00962G.Broccoli consumption affects the human gastrointestinal microbiota
                                                        

- (Peer Reviewed Journal)Kaczmarek, J.L., Liu, X., Charron, C.S., Novotny, J., Jeffery, E.H., Seifried, H.E., Ross, S.A., Miller, M.J., Swanson, K.S., Holscher, H.D. 2019. Broccoli consumption affects the human gastrointestinal microbiota. Journal of Nutritional Biochemistry. 63:27-34. https://doi.org/10.1016/j.jnutbio.2018.09.015.Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of body mass index and daily consumption
                                                        

- (Peer Reviewed Journal)Charron, C.S., Vinyard, B.T., Ross, S., Seifried, H., Jeffrey, E., Novotny, J. 2018. Absorption and metabolism of isothiocyanates formed from broccoli glucosinolates: effects of body mass index and daily consumption. British Journal of Nutrition. 120:1370-1379. https://doi.org/10.1017/S0007114518002921.Consumption of cashew nuts does not influence blood lipids or other markers of cardiovascular disease in humans: a randomized controlled trial
                                                        

- (Peer Reviewed Journal)Baer, D.J., Novotny, J. 2019. Consumption of cashew nuts does not influence blood lipids or other markers of cardiovascular disease in humans: a randomized controlled trial. American Journal of Clinical Nutrition. 109:269-275.  https://doi.org/10.1093/ajcn/nqy242.Blackberry feeding increases fat oxidation and improves insulin sensitivity in overweight and obese males
                                                        

- (Peer Reviewed Journal)Solverson, P.M., Rumpler, W.V., Leger, J.L., Redan, B.W., Ferruzzi, M.G., Baer, D.J., Castonguay, T.W., Novotny, J. 2018. Blackberry feeding increases fat oxidation and improves insulin sensitivity in overweight and obese males. Nutrients. 10. https://doi.org/10.3390/nu10081048.Limited appearance of apocarotenoids is observed in plasma after consumption of tomato juices: a randomized human clinical trial
                                                        

- (Peer Reviewed Journal)Cooperstone, J.L., Novotny, J., Riedl, K.M., Cichon, M.J., Francis, D.M., Curley, R.W., Schwartz, S.J., Harrison, E.H. 2018. Limited appearance of apocarotenoids is observed in plasma after consumption of tomato juices: a randomized human clinical trial. American Journal of Clinical Nutrition. 108:784-792. https://doi.org/10.1093/ajcn/nqy177.Dietary intakes of flavan-3-ols and cardiovascular health: a field synopsis using evidence mapping of randomized trials and prospective cohort studies
                                                        

- (Peer Reviewed Journal)Raman, G., Shams-White, M., Avendano, E., Chen, F., Novotny, J., Cassidy, A. 2018. Dietary intakes of flavan-3-ols and cardiovascular health: a field synopsis using evidence mapping of randomized trials and prospective cohort studies. Systematic Reviews. 7. https://doi.org/10.1186/s13643-018-0764-z.Almond consumption and processing affects the composition of the gastrointestinal microbiota of healthy adult men and women: a randomized controlled trial
                                                        

- (Peer Reviewed Journal)Holscher, H.D., Taylor, A.M., Swanson, K.S., Novotny, J., Baer, D.J. 2018. Almond consumption and processing affects the composition of the gastrointestinal microbiota of healthy adult men and women: a randomized controlled trial. Nutrients. 10. https://doi.org/10.3390/nu10020126.Walnut consumption alters the gastrointestinal microbiota, microbially derived secondary bile acids, and health markers in healthy adults: a randomized controlled trial
                                                        

- (Peer Reviewed Journal)Holscher, H.D., Guetterman, H.M., Swanson, K.S., An, R., Matthan, N., Lichtenstein, A., Novotny Dura, J., Baer, D.J. 2018. Walnut consumption alters the gastrointestinal microbiota, microbially derived secondary bile acids, and health markers in healthy adults: a randomized controlled trial. Journal of Nutrition. 148:861-867. https://doi.org/10.1093/jn/nxy004.Molybdenum
                                                        

- (Review Article)Novotny, J.A., Peterson, C.A. 2018. Molybdenum. Advances in Nutrition. 9:272-273. https://doi.org/10.1093/advances/nmx001.Vitamin A
                                                        

- (Review Article)Debelo, H., Novotny, J.A., Ferruzzi, M.G. 2017. Vitamin A. Advances in Nutrition. 8:992-994. https://doi.org/10.3945/an.116.014720.The effects of 100% wild blueberry (Vaccinium angustifolium) juice consumption on cardiometablic biomarkers: a randomized, placebo-controlled, crossover trial in adults with increased risk for type 2 diabetes
                                                        

- (Peer Reviewed Journal)Stote, K.S., Sweeney, M.I., Kean, T., Baer, D.J., Novotny, J., Shakerley, N.L., Chandrasekaran, A., Carrico, P., Melendez, J.A., Gottschall-Pass, K.T. 2017. The effects of 100% wild blueberry (Vaccinium angustifolium) juice consumption on cardiometablic biomarkers: a randomized, placebo-controlled, crossover trial in adults with increased risk for type 2 diabetes. Biomed Central (BMC) Nutrition. 3. https://doi.org/10.1186/s40795-017-0164-0.The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans
                                                        

- (Peer Reviewed Journal)Novotny, J., Chen, T., Terekhov, A., Gebauer, S.K., Baer, D.J., Ho, L., Pasinetti, G., Ferruzzi, M.G. 2017. The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans. Molecular Nutrition and Food Research. 61. https://doi.org/10.1002/mnfr.201700043.Adaptation in Caco-2 human intestinal cell differentiation and phenolic transport with chronic exposure to phenolic-rich blackberry (Rubus sp.) extract

- (Peer Reviewed Journal)Redan, B.W., Albaugh, G.P., Charron, C.S., Novotny, J.A., Ferruzzi, M.G. 2017. Adaptation in Caco-2 human intestinal cell differentiation and phenolic transport with chronic exposure to phenolic-rich blackberry (Rubus sp.) extract. Journal of Agricultural and Food Chemistry. 65:2694-2701.Food processing and structure impact the metabolizable energy of almonds

- (Peer Reviewed Journal)Gebauer, S.K., Novotny, J., Bornhorst, G.M., Baer, D.J. 2016. Food processing and structure impact the metabolizable energy of almonds. Food & Function. 7:4231-4238.Altered transport and metabolism of phenolic compounds in obesity and diabetes: implications for functional food development and assessment

- (Peer Reviewed Journal)Redan, B.W., Buhman, K.K., Novotny, J.A., Ferruzzi, M.G. 2016. Altered transport and metabolism of phenolic compounds in obesity and diabetes: Implications for functional food development and assessment. Advances in Nutrition. 7:1090-1104.A single meal containing raw, crushed garlic influences expression of immunity- and cancer-related genes in whole blood of humans

- (Peer Reviewed Journal)Charron, C.S., Dawson, H.D., Albaugh, G.P., Solverson, P.M., Vinyard, B.T., Solano Aguilar, G., Molokin, A., Novotny Dura, J. 2015. A single meal containing raw, crushed garlic influences expression of immunity- and cancer-related genes in whole blood of humans. Journal of Nutrition. 145:2448-2455.The impact of cranberries on gut microbiota and cardiometabolic health: proceedings of the cranberry health research conference

- (Peer Reviewed Journal)Blumberg, J.B., Basu, A., Krueger, C.G., Lila, M.A., Neto, C.C., Novotny, J., Reed, J.D., Rodriguez-Mateos, A., Toner, C.D. 2016. The impact of cranberries on gut microbiota and cardiometabolic health: Proceedings of the cranberry health research conference. Advances in Nutrition. 7:759-770.Current capabilities and limitations of the stable isotope technologies and applied mathematical equations in determining whole body vitamin A status

- (Peer Reviewed Journal)Lietz, G., Furr, H., Gannon, B., Green, M., Haskell, M., Lopez-Teros, V., Novotny, J.A., Palmer, A., Russell, R., Tanumihardjo, S. 2016. Current capabilities and limitations of the stable isotope technologies and applied mathematical equations in determining whole body vitamin A status. Food and Nutrition Bulletin. 37:S87-S103.Absorption and distribution kinetics of the 13C-labeled tomato carotenoid phytoene in healthy adults

- (Peer Reviewed Journal)Moran, N.E., Novotny Dura, J., Cichon, M., Riedl, K., Rogers, R., Grainger, E., Schwartz, S., Erdman, J., Clinton, S. 2016. Absorption and distribution kinetics of the 13C-labeled tomato carotenoid phytoene in healthy adults. Journal of Nutrition. 146:368-376.Walnuts consumed by healthy adults provide less available energy than predicted by the Atwater factors

- (Peer Reviewed Journal)Baer, D.J., Gebauer, S.K., Novotny Dura, J. 2016. Walnuts consumed by healthy adults provide less available energy than predicted by the Atwater factors. Journal of Nutrition. 146:9-13.Compartmental and noncompartmental modeling of 13C-lycopene absorption, isomerization, and distribution kinetics in healthy adults

- (Peer Reviewed Journal)Moran, N.E., Cichon, M., Riedl, K., Grainger, E., Schwartz, S., Novotny Dura, J., Erdman, J., Clinton, S. 2015. Compartmental and noncompartmental modeling of 13C-lycopene absorption, isomerization, and distribution kinetics in healthy adults. American Journal of Clinical Nutrition. 102:1436-1449.Separation of lipoproteins for quantitative analysis of 14C-labeled lipid soluble compounds

- (Peer Reviewed Journal)Cranberry juice consumption lowers markers of cardiometabolic risk, including blood pressure and circulating c-reactive protein, triglyceride, and glucose concentrations in adults

- (Peer Reviewed Journal)Novotny Dura, J., Baer, D.J., Khoo, C., Gebauer, S., Charron, C.S. 2015. Cranberry juice consumption lowers markers of cardiometabolic risk, including blood pressure and circulating c-reactive protein, triglyceride, and glucose concentrations in adults. Journal of Nutrition. 145:1185-1193.Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCOM1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults

- (Peer Reviewed Journal)Andrew, C.J., Gonzalo, R., Janel, O., Juan, M., Moshfegh, A.J., Baer, D.J., Novotny Dura, J. 2013. Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCOM1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults. Lipids in Health and Disease. 12:66-75.Dietary intake of advanced glycation end products did not affect endothelial function and inflammation in healthy adults in a randomized controlled trial

- (Peer Reviewed Journal)Semba, R.D., Gebauer, S., Baer, D.J., Sun, K., Turner, R., Silber, H.A., Talegawkar, S., Ferrucci, L., Novotny Dura, J. 2014. Dietary intake of advanced glycation end products did not affect endothelial function and inflammation in healthy adults in a randomized controlled trial. American Journal of Clinical Nutrition. 144(7):1037-1042.Effects of almond and pistachio consumption on gut microbiota composition in a randomised cross-over human feeding study

- (Peer Reviewed Journal)Ukhanona, M., Wang, X., Baer, D.J., Novotny Dura, J., Fredborg, M., Mai, V. 2014. Effects of almond and pistachio consumption on gut microbiota composition in a randomised cross-over human feeding study. British Journal of Nutrition. 111(12):2146-2152.Kinetics, bioavailability, and metabolism of RRR-alpha-tocopherol in humans supports lower requirement for vitamin E

- (Peer Reviewed Journal)Novotny Dura, J., Fadel, J.G., Holstege, D.M., Furr, H.C., Clifford, A.J. 2012. Kinetics, bioavailability, and metabolism of RRR-alpha-tocopherol in humans supports lower requirement for vitamin E. Journal of Nutrition. 142:2105-2111.Effect of cocoa and green tea on biomarkers of glucose regulation, oxidative stress, inflammation and hemostasis in obese adults at risk for insulin resistance

- (Peer Reviewed Journal)Stote, K.S., Clevidence, B.A., Novotny Dura, J., Henderson, T.R., Radecki, S.V., Baer, D.J. 2012. Effect of cocoa and green tea on biomarkers of glucose regulation, oxidative stress, inflammation and hemostasis in obese adults at risk for insulin resistance. European Journal of Clinical Nutrition. 66:1153-1159.Assessment of DNA damage and repair in adults consuming allyl isothiocyanate or Brassica vegetables

- (Peer Reviewed Journal)Charron, C.S., Clevidence, B.A., Albaugh, G.P., Milner, J., Novotny Dura, J. 2012. Assessment of DNA damage and repair in adults consuming allyl isothiocyanate or Brassica vegetables. Journal of Nutritional Biochemistry. 24:894-902.Discrepancy between Atwater factor predicted and empirically measured energy value of almonds in human diets

- (Peer Reviewed Journal)Novotny Dura, J., Gebauer, S.K., Baer, D.J. 2012. Discrepancy between Atwater factor predicted and empirically measured energy value of almonds in human diets. American Journal of Clinical Nutrition. 96:296-301.Anthocyanins and heart disease

- (Book / Chapter)Novotny Dura, J. 2012. Anthocyanins and heart disease. In: Carkeet, C., Grann, K., Randolph, R.K., Venzon, D.S., Izzy, S. Phytochemicals: Health Promotion and Therapeutic Potential. Boca Raton, FL: Taylor and Francis CRC Press. p. 559-568.Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2R, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.

- (Peer Reviewed Journal)Novotny Dura, J., Baer, D.J., Chen, K., Gonzalo, R., Kim, S., Holstege, D., Owens, J., Liu, B., Muller, H., Medrano, J., Fadel, J., Clifford, A., Mcwade, L., Moshfegh, A.J. 2012. Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults. Journal of Nutrition. 142:1764-1771.Anthocyanin bioavailability: Past progress and current challenges

- (Book / Chapter)Novotny Dura, J. 2012. Anthocyanin bioavailability: Past progress and current challenges. In: Patil B.S., Jayaprakasha G.K., Chidambara Murthy K.N., Seeram, N.P. Emerging Trends in Dietary Components for Preventing and Combating Disease. Washington, DC: American Chemical Society. p.559-568.An HPLC-MS method for d8-ß-carotene and d4-retinyl esters useful in studies of ß-carotene absorption and its conversion to vitamin A in humans

- (Peer Reviewed Journal)Fleshman, M.K., Riedl, K., Novotny Dura, J., Schwartz, S.J., Harrison, E.H. 2012. An HPLC-MS method for d8-ß-carotene and d4-retinyl esters useful in studies of ß-carotene absorption and its conversion to vitamin A in humans. Journal of Lipid Research. 53:820-827.Anthocyanin kinetics are dependent on anthocyanin structure

- (Peer Reviewed Journal)Novotny Dura, J., Clevidence, B.A., Kurilich, A.C. 2011. Anthocyanin kinetics are dependent on anthocyanin structure. British Journal of Nutrition. 107:504-509.The measured energy value of pistachio nuts in the human diet

- (Peer Reviewed Journal)Baer, D.J., Gebauer, S.K., Novotny Dura, J. 2011. The measured energy value of pistachio nuts in the human diet. British Journal of Nutrition. 28:1-6.Molybdenum nutriture in humans

- (Peer Reviewed Journal)Novotny Dura, J. 2011. Molybdenum nutriture in humans. Evidence-based Complementary and Alternative Medicine. 16(3):164-168.Oolong tea does not improve glucose metabolism in non-diabetic adults

- (Peer Reviewed Journal)Baer, D.J., Novotny Dura, J., Harris, K., Stote, K., Clevidence, B.A., Rumpler, W.V. 2010. Oolong tea does not improve glucose metabolism in non-diabetic adults. European Journal of Clinical Nutrition. 65:87-93.Beta-carotene conversion to vitamin A decreases as the dietary dose increases in humans

- (Peer Reviewed Journal)Novotny Dura, J., Harrison, D.J., Pawlosky, R., Flanagan, V.P., Harrison, E.H., Kurilich, A.C. 2010. Beta-Carotene conversion to vitamin A decreases as the dietary dose increases in humans. Journal of Nutrition. 140(5):915-918.Vitamin K absorption and kinetics in human subjects after consumption of 13C-labeled phylloquinone from kale

- (Peer Reviewed Journal)Novotny Dura, J., Kurilich, A.C., Britz, S.J., Baer, D.J., Clevidence, B.A. 2010. Vitamin K absorption and kinetics in human subjects after consumption of 13C-labeled phylloquinone from kale. British Journal of Nutrition. 104(6):858-62.Bioavailability of Anthocyanins from Purple Carrot Juice: Effects of Acylation and Plant Matrix

- (Peer Reviewed Journal)Charron, C.S., Kurilich, A.C., Clevidence, B.A., Simon, P.W., Harrison, D.J., Britz, S.J., Baer, D.J., Novotny Dura, J. 2009. Bioavailability of Anthocyanins from Purple Carrot Juice: Effects of Acylation and Plant Matrix. Journal of Agricultural and Food Chemistry. 57(4):1226-1230.Isotopic Labeling of Red Cabbage Anthocyanins with Atmospheric 13-CO2

- (Peer Reviewed Journal)Charron, C.S., Britz, S.J., Mirecki, R.M., Harrison, D.J., Clevidence, B.A., Novotny, J.  2008. Isotopic labeling of red cabbage anthocyanins with atmospheric 13-CO2. J. Amer. Soc. Hort. Sci.  133(3):351-359.Anthocyanin excretion increases linearly with increasing strawberry dose.

- (Peer Reviewed Journal)Carkeet, C., Clevidence, B.A., Novotny, J. 2008. Anthocyanin excretion by humans increases linearly with increasing strawberry dose. Journal of Nutrition.  138(5):897-902.Role of Color and Pigments in Breeding, Genetics, and Nutritional Improvement of Carrots

- (Book / Chapter)Simon, P.W., Tanumihardjo, S.A., Clevidence, B.A., Novotny Dura, J. 2008. Role of Color and Pigments in Breeding, Genetics, and Nutritional Improvement of Carrots. In: Culver, C.A., Wrolstad, R.E., editors. Color Quality of Fresh and Processed Foods. Washington, D.C.: Oxford University Press. p. 151-165.EFFECTS OF ANTHOCYANIN AND CAROTENOID COMBINATIONS ON FOLIAGE AND IMMATURE FRUIT COLOR OF CAPSICUM ANNUM L.

- (Peer Reviewed Journal)Lightbourn, G., Griesbach, R., Novotny Dura, J., Clevidence, B.A., Rao, D.D., Stommel, J.R. 2008. Effects of anthocyanin and carotenoid combinations on foliage and immature fruit color of capsicum annum l. Journal of Heredity. 99:105-111.Anthocyanins Present in Some Tropical Fruits.

- (Peer Reviewed Journal)Brito, E., Araujo, M., Alves, R., Clevidence, B.A., Novotny Dura, J. 2007. Anthocyanins present in some tropical fruits.  Journal of Agricultural and Food Chemistry.  55:9389-9394.Dynamic Modeling of Molybdenum Metabolism in Humans

- (Book / Chapter)Novotny Dura, J., Turnlund, J.R. 2007. Dynamic Modeling of Molybdenum Metabolism in Humans.  Virginia: Virginia Polytechnic University. p. 39-50.The Effect of Dose Size on Bioavailability of Acylated and Nonacylated Anthocyanins from Red Cabbage (Brassica oleracea L. var. capitata)

- (Peer Reviewed Journal)Charron, C.S., Clevidence, B.A., Britz, S.J., Novotny Dura, J. 2007. The effect of dose size on bioavailability of acylated and nonacylated anthocyanins from red cabbage (Brassica oleracea L. var. capitata). Journal of Agricultural and Food Chemistry. 55(13):5354-5362.The Effect of Dose Size on Bioavailability of Acylated and Nonacylated Anthocyanins from Red Cabbage

- (Abstract Only)Charron, C.S., Clevidence, B.A., Britz, S.J., Novotny Dura, J. 2007. The Effect of Dose Size on Bioavailability of Acylated and Nonacylated Anthocyanins from Red Cabbage [abstract]. Experimental Biology. p. 240.7.A FEASIBILITY STUDY TO QUANTIFY IN VIVO HUMAN ALPHA-TOCOPHEROL METABOLISM

- (Peer Reviewed Journal)Clifford, A.J., Demoura, F.F., Ho, C.C., Chuang, J.C., Follett, J., Fadel, J.G., Vogel, J.S., Novotny Dura, J., Cohn, W. 2006. A feasibility study to quantify in vivo human alpha-tocopherol metabolism.  American Journal of Clinical Nutrition. 84(6):1430-1441.A feasibiity study to quantify in vivo human alpha-tocopherol metabolism

- (Peer Reviewed Journal)Clifford, A.J., De Moura, F.F., Ho, C.C., Chuang, J.C., Follett, J.R., Fadel, J.G., Novotny Dura, J. 2006. A feasibiity study to quantify in vivo human alpha-tocopherol metabolism. American Journal of Clinical Nutrition. 84(6):1430-1441.MOLYBDENUM INTAKE INFLUENCES MOLYBDENUM KINETICS IN HUMANS.

- (Peer Reviewed Journal)Novotny Dura, J., Turnlund, J.R. 2007. Molybdenum intake influences molybdenum kinetics in humans. Journal of Nutrition. 137:37-42.STABILITY OF URINARY METABOLITES OF STRAWBERRY ANTHOCYANINS

- (Abstract Only)Carkeet, C., Clevidence, B.A., Novotny Dura, J. 2006. Stability of urinary metabolites of strawberry anthocyanins. Federation of American Societies for Experimental Biology Conference.MOLYBDENUM DISPOSITION IN HUMANS DURING MOLYBDENUM DEPLETION AND REPLETION.

- (Peer Reviewed Journal)Novotny Dura, J., Turnlund, J.R. 2006. Molybdenum disposition in humans during molybdenum depletion and repletion. Journal of Nutrition 136:953-957.EFFECT OF COOKING METHOD ON XANTHOPHYLL CONTENT OF YELLOW-FLESHED POTATO

- (Proceedings)Clevidence, B.A., Haynes, K.G., Rao, D.D., Novotny Dura, J. 2005. Effect of cooking method on xanthophyll content of yellow-fleshed potato. United States Japan Natural Resources Protein Panel. 34:280-284.WHAT CAN PHARMACOKINETIC MODELS TELL US ABOUT THE DISPOSITION OF LYCOPENE AND THE POTENTIAL ROLE OF LYCOPENE IN CANCER PREVENTION?

- (Proceedings)Novotny Dura, J. 2005. What can pharmacokinetic models tell us about the disposition of lycopene and the potential role of lycopene in cancer prevention? Journal of Nutrition 135:2048S-2049S.PLASMA AND URINE RESPONSES ARE LOWER FOR ACYLATED VS NONACYLATED ANTHOCYANINS FROM RAW AND COOKED PURPLE CARROT.

- (Peer Reviewed Journal)Kurilich, A.C., Clevidence, B.A., Britz, S.J., Simon, P.W., Novotny Dura, J. 2005. Plasma and urine responses are lower for acylated vs nonacylated anthocyanins from raw and cooked purple carrot. Journal of Agricultural and Food Chemistry. 53:6537-6542.PLASMA APPERANCE OF LABELED BETA-CAROTENE, LUTEIN, AND RETINOL IN HUMANS AFTER CONSUMPTION OF ISOTOPICALLY LABELED-KALE

- (Peer Reviewed Journal)Novotny Dura, J., Kurilich, A.C., Britz, S.J., Clevidence, B.A. 2005. Plasma appearance of labeled beta-carotene, lutein, and retinol in human consumption of iso topically-labeled kale. Available online: http://pubs.acs.org/cgi-bin/asap.cgi/jafcau/asap/html/jf050570o.html.BIOAVAILABILITY OF ANTHOCYANINS FROM RAW AND COOKED PURPLE CARROTS.

- (Proceedings)Clevidence, B.A., Kurilich, A.C., Britz, S., Simon, P.W., Novotny Dura, J. 2004. Bioavailability of anthocyanins from raw and cooked purple carrots. Proceedings of the 33rd U.S.-Japan Cooperative Program in Natural Resources. UJNR 33:171-174.MATHEMATICAL INVESTIGATIONS OF CAROTENOID KINETICS IN HUMANS.

- (Book / Chapter)Novotny Dura, J. 2005. Mathematical investigations of carotenoid kinetics in humans. Mathematical Modeling in Health and Toxicology. Athens, GA: Mathematical Biology Press. 189-204.COMPARTMENTAL MODELING OF 14C-LYCOPENE IN THE F344 RAT

- (Abstract Only)Novotny Dura, J., Zaripheh, S., Erdman, J. 2004. Compartmental modeling of 14c-lycopene in the f344 rat. Experimental Biology.APPEARANCE OF LABELED BETA-CAROTENE, LUTEIN, RETINOL, AND PHYLLOQUINONE IN PLASMA AFTER CONSUMPTION OF ISOTOPICALLY-LABELED KALE.

- (Abstract Only)Novotny Dura, J., Kurilich, A.C., Britz, S.J., Baer, D.J., Clevidence, B.A. 2004. Appearance of labeled beta-carotene, lutein, retinol, and phylloquinone in plasma after consumption of isotopically-labeled kale. Journal of Lipid Research 46:1896-903LABELED BETA-CAROTENE AND LUTEIN IN PLASMA AFTER CONSUMPTION OF ISOTOPICALLY-LABELED KALE

- (Abstract Only)Novotny Dura, J., Kurilich, A.C., Britz, S.J., Clevidence, B.A. 2004. Labeled beta-carotene and lutein in plasma after consumption of isotopically-labeled kale. Carotenoid Gordon Conference.ESSENTIAL FEATURES OF PHYTONUTRIENT KINETIC STUDIES.

- (Abstract Only)Novotny Dura, J. 2003. Essential features of phytonutrient kinetic studies.. Meeting Abstract.INTERACTIONS BETWEEN GENDER AND FOOD INTAKE ON THE RELATIONSHIP BETWEEN ENERGY EXPENDITURE AND BODY COMPOSITION.

- (Peer Reviewed Journal)Paul, D.R., Novotny Dura, J., Rumpler, W.V. 2004. Interactions between gender and food intake on the relationship between energy expenditure and body composition. American Journal of Clinical Nutrition. 79:385-389.STRUCTURAL CHARACTERIZATION AND IMPROVED DETECTION OF KALE FLAVONOIDS BY ELECTROSPRAY IONIZATION MASS SPECTROMETRY.

- (Peer Reviewed Journal)Zhang, J., Satterfield, M., Brodbelt, J., Britz, S.J., Clevidence, B.A., Novotny Dura, J. 2003. Structural characterization and improved detection of kale flavonoids by electrospray ionization mass spectrometry. Analytical Chemistry. 75(23):6401-07.ISOTOPIC LABELING AND LC-APCI-MS QUANTIFICATION FOR INVESTIGATING ABSORPTION OF CAROTENOIDS AND VITAMIN K1 FROM KALE

- (Peer Reviewed Journal)Kurilich, A.C., Britz, S.J., Clevidence, B.A., Novotny Dura, J. 2003. Isotopic labeling and lc-apci-ms quantification for investigating absorption of carotenoids and vitamin k1 from kale. Journal of Agricultural and Food Chemistry.51(7):4877-4889.A PHYSIOLOGICAL COMPARTMENTAL MODEL DESCRIBING THE DYNAMICS OF LYCOPENE METABOLISM IN HEALTHY MEN.

- (Peer Reviewed Journal)Diwadkar-Navsariwala, V., Novotny Dura, J., Gustin, G.M., Rodvold, K.A., Sosman, J.A., Stacewicz-Sapuntzaki, J., Murray, J.L., Tiller, P.A., Bowen, P.E. 2003. A physiological compartmental model describing the dynamics of lycopene metabolism in healthy men. Journal of Lipid Research.44(10):1927-39.THE TIME COURSE DISTRIBUTION OF A SINGLE DOSE OF 14C-LYCOPENE IN THE F344 RAT.

- (Abstract Only)Zaripheh, S., Cooke, P., Novotny Dura, J., Erdman, J.W. 2003. The time course distribution of a single dose of 14c-lycopene in the f344 rat. Meeting Abstract.THE EFFECT OF DAILY ALCOHOL INTAKE ON BREATH ALCOHOL CONCENTRATIONS OF POST-MENOPAUSAL WOMEN AFTER A BOLUS DOSE.

- (Peer Reviewed Journal)Novotny Dura, J., Rumpler, W.V., Baer, D.J., Judd, J.T. 2003. The effect of daily alcohol intake on breath alcohol concentrations of post-menopausal women after a bolus dose. Alcohol and Alcoholism. 64:380-383.WINSAAM:  SOFTWARE FOR SIMULATION, ANALYIS, AND MODELING

- (Peer Reviewed Journal)Novotny Dura, J., Greif, P., Boston, R.C. 2003. Winsaam: Software for simulation, analyis, and modeling. Advances in Experimental Medicine and Biology. 537:343-356PERSONALITY CHARACTERISTICS AS PREDICTORS OF UNDER-REPORTING OF ENERGY INTAKE ON 24H DIETARY RECALLS

- (Peer Reviewed Journal)Novotny Dura, J., Rumpler, W.V., Riddick, H., Judd, J.T., Baer, D.J., Mcdowell, M., Hebert, J., Briefel, R. 2003. Personality characteristics as predictors of under-reporting of energy intake on 24h dietary recalls. Journal Of The American Dietetic Association. 103:1146-1151NUTRITIONAL ASSESSMENT OF COLORED CARROTS

- (Abstract Only)Kurilich, A.C., Novotny Dura, J., Clevidence, B.A., Britz, S.J. 2002. Nutritional assessment of colored carrots. BARC Poster Day.INTRINSIC LABELING OF PLANTS FOR NUTRIENT BIOAVAILABILITY STUDIES

- (Peer Reviewed Journal)Novotny Dura, J., Britz, S.J., Caulfield, F.A., Beecher, G.R., Clevidence, B.A. 2003. Intrinsic labeling of plants for nutrient bioavailability studies. Advances in Experimental Medicine and Biology.537:131-140.DETERMINATION OF 13C-LABELED AND ENDOGENOUS BETA-CAROTENE, LUTEIN, AND     VITAMIN A IN HUMAN PLASMA USING QUANTITATIVE MASS SPECTROMETRY

- (Peer Reviewed Journal)Kelm, M., Flanagan, V.P., Pawlosky, R.J., Novotny Dura, J., Clevidence, B.A., Britz, S.J. 2001. Determination of 13c-labeled and endogenous beta-carotene, lutein, and vitamin a in human plasma using quantitative mass spectrometry. Lipids.36:1277-1282.ABSORPTION OF BETA-CAROTENE FROM CARBON-13 LABELED KALE

- (Abstract Only)Novotny Dura, J., Britz, S.J., Pawlosky, R.J., Harrison, D.J., Kelm, M.A., Flanagan, V.P., Brown, E., Beecher, G.R., Clevidence, B.A. 2001. Absorption of beta-carotene from carbon-13 labeled kale. Experimental Biology.A PHYSIOLOGIC COMPARTMENTAL ANALYSIS OF ALPHA-LINOLENIC ACID METABOLISM    IN ADULT HUMANS

- (Peer Reviewed Journal)Pawlosky, R.J., Novotny Dura, J., Hibbeln, J., Salem, Jr, N. 2001. A physiologic compartmental analysis of alpha-linolenic acid metabolism    in adult humans. Journal of Lipid Research. 42(8):1257-1265METHODS FOR DETERMINING THE METABOLISM OF ALPHA-LINOLENIC ACID IN HUMANS   FROM INTRINSICALLY-LABLED FOOD

- (Peer Reviewed Journal)Pawlosky, R.J., Novotny Dura, J., Britz, S.J., Clevidence, B.A. 2001. Methods for determining the metabolism of alpha-linolenic acid in humans   from intrinsically-labled food. Present Knowledge in Nutrition.  Book Chapter.56:75-77.AN LC/PB METHOD FOR THE ANALYSIS OF 13 C LABELED LUTEIN AND B-CAROTENE IN  KALE AND HUMAN PLASMA   (BARC POSTER DAY, 2000)

- (Abstract Only)Kelm, M.A., Flanagan, V.P., Pawlosky, R.J., Novotny Dura, J., Britz, S.J. 2000. An lc/pb method for the analysis of 13 c labeled lutein and b-carotene in  kale and human plasma. (BARC Poster Day, 2000). Meeting Abstract.A SENSITIVE PROCEDURE FOR THE STUDY OF BETA-CAROTENE-D8 METABOLISM IN      HUMANS USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY

- (Peer Reviewed Journal)Pawlosky, R.J., Flanagan, V.P., Novotny Dura, J. 2000. A sensitive procedure for the study of beta-carotene-d8 metabolism in humans using liquid chromatography-mass spectrometry. Journal of Lipid Research. 41:1027-1031.A STABLE ISOTOPE LC-MS PROCEDURE TO STUDY THE METABOLISM OF 2H8-BETA-      CAROTENE IN HUAMNS   (EXPERIMENTAL BIOLOGY '99)

- (Abstract Only)Pawlosky, R.J., Novotny Dura, J., Flanagan, V.P. 1999. A stable isotope lc-ms procedure to study the metabolism of 2h8-beta-carotene in humans   (experimental biology '99). Meeting Abstract.COMPARTMENTAL MODELING AND BALANCE STUDIES

- (Book / Chapter)COMPARTMENTAL MODELING OF HUMAN LACTATION

- (Peer Reviewed Journal)PROTON AND HYDROXIDE DECAY KINETICS IN BUFFERED VESCILES

- (Abstract Only)MODELING OF ENERGY EXPENDITURE AND RESTING METABOLIC RATE DURING WEIGHT    LOSS IN HUMANS

- (Peer Reviewed Journal)
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