# Patent

## Title
Analysis of the mirror neuron system for evaluation of stimulus

## Abstract

The human mirror neuron system includes neurons that fire both when an individual performs an action and when the individual observes the action being performed by another. Neuro-response data involving the mirror neuron system is collected as a subject is exposed to stimulus material. The stimulus material may include individuals performing actions such as making a purchase, accepting an offer, participating in an activity, etc. Neuro-response data involving the mirror neuron system of the subject is analyzed to determine the propensity of the subject to act.

## Background
CROSS REFERENCE TO RELATED APPLICATIONS
This patent is related to U.S. patent application Ser. No. 12/056,190; U.S. patent application Ser. No. 12/056,211; U.S. patent application Ser. No. 12/056,221; U.S. patent application Ser. No. 12/056,225; U.S. patent application Ser. No. 12/113,863; U.S. patent application Ser. No. 12/113,870; U.S. patent application Ser. No. 12/122,240; U.S. patent application Ser. No. 12/122,253; U.S. patent application Ser. No. 12/122,262; U.S. patent application Ser. No. 12/135,066; U.S. patent application Ser. No. 12/135,074; U.S. patent application Ser. No. 12/182,851; U.S. patent application Ser. No. 12/182,874; U.S. patent application Ser. No. 12/199,557; U.S. patent application Ser. No. 12/199,583; U.S. patent application Ser. No. 12/199,596; U.S. patent application Ser. No. 12/200,813; U.S. patent application Ser. No. 12/234,372; U.S. patent application Ser. No. 12/135,069; U.S. patent application Ser. No. 12/234,388; U.S. patent application Ser. No. 12/544,921; U.S. patent application Ser. No. 12/544,934; U.S. patent application Ser. No. 12/546,586; U.S. patent application Ser. No. 12/544,958; U.S. patent application Ser. No. 12/846,242; U.S. patent application Ser. No. 12/410,380; U.S. patent application Ser. No. 12/410,372; U.S. patent application Ser. No. 12/413,297; U.S. patent application Ser. No. 12/608,660; U.S. patent application Ser. No. 12/608,685; U.S. patent application Ser. No. 13/444,149; U.S. patent application Ser. No. 12/608,696; U.S. patent application Ser. No. 12/731,868; U.S. patent application Ser. No. 13/045,457; U.S. patent application Ser. No. 12/778,810; U.S. patent application Ser. No. 12/778,828; U.S. patent application Ser. No. 13/104,821; U.S. patent application Ser. No. 13/104,840; U.S. patent application Ser. No. 12/853,197; U.S. patent application Ser. No. 12/884,034; U.S. patent application Ser. No. 12/868,531; U.S. patent application Ser. No. 12/913,102; U.S. patent application Ser. No. 12/853,213; and U.S. patent application Ser. No. 13/105,774.
TECHNICAL FIELD
The present disclosure relates to analyzing the mirror neuron system for evaluation of stimulus materials.
DESCRIPTION OF RELATED ART
Conventional systems for evaluating stimulus materials such as programs, advertising, text, images, video, audio, scents, tastes, materials, offers, and games are usually limited to survey and focus group based review. However, conventional systems are subject to semantic, syntactic, metaphorical, cultural, and interpretive errors that prevent accurate and repeatable evaluation.
Consequently, it is desirable to provide improved methods and apparatus for evaluating stimulus materials.



BRIEF DESCRIPTION OF THE DRAWINGS
The disclosure may best be understood by reference to the following description taken in conjunction with the accompanying drawings, which illustrate particular example embodiments.
FIG. 1 illustrates one example of a system for performing mirror neuron system analysis using neuro-response data.
FIG. 2 illustrates examples of stimulus attributes that can be included in a repository.
FIG. 3 illustrates examples of data models that can be used with a mirror neuron system analyzer.
FIG. 4 illustrates one example of a query that can be used with the mirror neuron system analyzer
FIG. 5 illustrates one example of a report generated using a mirror neuron system analyzer.
FIG. 6 illustrates one example of a technique for performing mirror neuron system analysis.
FIG. 7 illustrates one example of technique for performing mirror neuron system analysis.
FIG. 8 provides one example of a system that can be used to implement one or more mechanisms.



DESCRIPTION OF PARTICULAR EMBODIMENTS
Reference will now be made in detail to some specific examples of the invention including the best modes contemplated by the inventors for carrying out the invention. Examples of these specific embodiments are illustrated in the accompanying drawings. While the invention is described in conjunction with these specific embodiments, it will be understood that it is not intended to limit the invention to the described embodiments. On the contrary, it is intended to cover alternatives, modifications, and equivalents as may be included within the spirit and scope of the invention as defined by the appended claims.
For example, the techniques and mechanisms of the present invention will be described in the context of particular types of stimulus. However, it should be noted that the techniques and mechanisms of the present invention apply to a variety of different types of stimulus. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. Particular example embodiments of the present invention may be implemented without some or all of these specific details. In other instances, well known process operations have not been described in detail in order not to unnecessarily obscure the present invention.
Various techniques and mechanisms of the present invention will sometimes be described in singular form for clarity. However, it should be noted that some embodiments include multiple iterations of a technique or multiple instantiations of a mechanism unless noted otherwise. For example, a system uses a processor in a variety of contexts. However, it will be appreciated that a system can use multiple processors while remaining within the scope of the present invention unless otherwise noted. Furthermore, the techniques and mechanisms of the present invention will sometimes describe a connection between two entities. It should be noted that a connection between two entities does not necessarily mean a direct, unimpeded connection, as a variety of other entities may reside between the two entities. For example, a processor may be connected to memory, but it will be appreciated that a variety of bridges and controllers may reside between the processor and memory. Consequently, a connection does not necessarily mean a direct, unimpeded connection unless otherwise noted.
Overview
The human mirror neuron system includes neurons that fire both when an individual performs an action and when the individual observes the action being performed by another. Neuro-response data involving the mirror neuron system is collected as a subject is exposed to stimulus material. The stimulus material may include individuals performing actions such as making a purchase, accepting an offer, participating in an activity, etc. Neuro-response data involving the mirror neuron system of the subject is analyzed to determine the propensity of the subject to act.
Example Embodiments
Neurons in the mirror neuron system are cells associated with the premotor cortex, a portion of the brain involved with planning, selection, and execution of actions. Neurons in the mirror neuron system have been observed in humans in the inferior frontal lobe and the posterior parietal lobe. These neurons are active both when an individual is performing an action and when the individual observes another performing the action. Some mirror neurons are believed to be active when activity is performed by another in peripersonal space and not when activity is performed by another in extrapersonal space. Others have noted that mirror neuron activity increases as the likelihood of interaction with the other individual performing the action increases. It is recognized that mirror neuron activity is particularly pronounced in the left hemisphere and in women.
Some scientists speculate that the mirror neuron system provides individuals with the ability experience an action performed by another as though the experience was their own. The mirror neuron system may be important in allowing individuals to imitate, learn, acquire language, show empathy, and understand others.
The techniques and mechanisms of the present invention recognize that the mirror neuron system can also be used to determine the propensity of an individual to perform an observed activity. According to various embodiments, an instruction series on how to use a fire extinguisher can be improved by analyzing mirror neuron system activity for subjects exposed to the instruction series. An advertisement showing an individual obtaining and using a product may be evaluated by analyzing mirror neuron system activity for subjects exposed to the advertisement. In some embodiments, a propensity to reach or obtain can be determined. A tourism video depicting an individual travelling to another country can be evaluated by analyzing mirror neuron system activity for potential tourists watching the video.
It is recognized that mu rhythms, having a frequency between 8-13 hertz, decrease when an individual performs an action or observes an action being performed by another. That is, mu rhythms decrease as mirror neuron activity increases. The techniques and mechanisms of the present invention further recognize that gamma rhythms increase as mirror neuron activity increases. According to various embodiments, mirror neuron system activity is measured using a ratio including gamma and/or mu. In particular embodiments, mirror neuron system activity is measured using a ratio including gamma and beta, which includes mu. In some examples, large gamma over mu or gamma over beta values indicate a high propensity to reach, obtain, or imitate. A propensity to reach, obtain, or imitate is referred to herein as a propensity to act. In particular embodiments, a propensity to act index is determined by measuring mirror neuron system activity when a subject is exposed to stimulus material having a human-like entity such as a human hand performing an action. How human-like the entity has to be may depend on the individual. Some individuals may have a mirror neuron system that is active when particular animals perform activities. Otherwise may have a mirror neuron system that is active when a computer animation of an individual is observed. A large gamma over mu or gamma over beta value also indicates that stimulus material may be effective.
It is recognized that various individuals, groups, and subgroups may have more pronounced mirror neuron system responses to stimulus material. In particular embodiments, women typically have significantly higher mirror neuron system responses than men. Consequently, a propensity to act index may be calibrated based on demographic group such as gender. According to various embodiments, neuro-response data is combined with survey responses and resulting behavior information to generate a propensity to reach index, a learning index, and an empathy index as well. In some examples, mirror neuron system patterns associated with particularly effective learning, high levels of empathy, or strong purchase desires are maintained in a mirror neuron system analysis repository. Stimulus materials that elicit similar mirror neuron system patterns for the same individuals, groups, or subgroups may be given higher propensity to reach indices, learning indices, or empathy indices.
Mirror neuron system activity can be measured by monitoring activity in regions associated with mirror neurons, such as the posterior parietal lobe and the inferior frontal lobe. In some examples, mirror neuron system activity can be measured using central nervous system measures such as Functional Magnetic Resonance Imaging (fMRI), Electroencephalography (EEG), Magnetoencephlography (MEG), and Optical Imaging. According to various embodiments, these central nervous system measures can be supplemented with other data including autonomic nervous system and effector measurements. In particular embodiments, a typical mirror neuron system exhibits a drop in mu rhythms and/or beta rhythms when an individual either acts or observes another person acting. According to various embodiments, the techniques and mechanisms of the present invention also measure the increase in gamma rhythms. The techniques and mechanisms of the present invention recognize that gamma rhythms increase when an individual acts or observes another acting.
Mechanisms for measuring mirror neuron system activity include central nervous system measurement mechanisms. Some examples of central nervous system measurement mechanisms include Functional Magnetic Resonance Imaging (fMRI), Electroencephalography (EEG), Magnetoencephlography (MEG), and Optical Imaging. Optical imaging can be used to measure the absorption or scattering of light related to concentration of chemicals in the brain or neurons associated with neuronal firing. MEG measures magnetic fields produced by electrical activity in the brain. fMRI measures blood oxygenation in the brain that correlates with increased neural activity. However, current implementations of fMRI have poor temporal resolution of few seconds. EEG measures electrical activity associated with post synaptic currents occurring in the milliseconds range. Subcranial EEG can measure electrical activity with the most accuracy, as the bone and dermal layers weaken transmission of a wide range of frequencies. Nonetheless, surface EEG provides a wealth of electrophysiological information if analyzed properly. Even portable EEG with dry electrodes provides a large amount of neuro-response information. Although the effect of stimulus materials on mirror neurons can be measured using central nervous system measurement mechanisms, the techniques and mechanisms of the present invention contemplate using other mechanisms to further validate the effectiveness of stimulus materials. For example, autonomic nervous system and effector measures can also be used.
Autonomic nervous system measurement mechanisms include Electrocardiograms (EKG), pupillary dilation, etc. Effector measurement mechanisms include Electrooculography (EOG), eye tracking, facial emotion encoding, reaction time etc.
According to various embodiments, the techniques and mechanisms of the present invention intelligently blend multiple modes and manifestations of precognitive neural signatures with cognitive neural signatures and post cognitive neurophysiological manifestations to more accurately perform mirror neuron system analysis. In some examples, autonomic nervous system measures are themselves used to validate central nervous system measures. Effector and behavior responses are blended and combined with other measures. According to various embodiments, central nervous system, autonomic nervous system, and effector system measurements are aggregated into a measurement that allows mirror neuron system analysis.
In particular embodiments, subjects are exposed to stimulus material and data such as central nervous system, autonomic nervous system, and effector data is collected during exposure. According to various embodiments, data is collected in order to determine a resonance measure that aggregates multiple component measures that assess resonance data. In particular embodiments, specific event related potential (ERP) analyses and/or event related power spectral perturbations (ERPSPs) are evaluated for different regions of the brain both before a subject is exposed to stimulus and each time after the subject is exposed to stimulus.
According to various embodiments, pre-stimulus and post-stimulus differential as well as target and distracter differential measurements of ERP time domain components at multiple regions of the brain are determined (DERP). Event related time-frequency analysis of the differential response to assess the attention, emotion and memory retention (DERPSPs) across multiple frequency bands including but not limited to theta, alpha, beta, gamma and high gamma is performed. In particular embodiments, single trial and/or averaged DERP and/or DERPSPs can be used to enhance the resonance measure and determine priming levels for various products and services.
A variety of stimulus materials such as entertainment and marketing materials, games, media, performances, sensory experiences, etc. can be analyzed. Stimulus materials may involve audio, visual, tactile, olfactory, taste, etc. According to various embodiments, enhanced neuro-response data is generated using a data analyzer that performs both intra-modality measurement enhancements and cross-modality measurement enhancements. According to various embodiments, brain activity is measured not just to determine the regions of activity, but to determine interactions and types of interactions between various regions. The techniques and mechanisms of the present invention recognize that interactions between neural regions support orchestrated and organized behavior. Attention, emotion, memory, and other abilities are not merely based on one part of the brain but instead rely on network interactions between brain regions.
The techniques and mechanisms of the present invention further recognize that different frequency bands used for multi-regional communication can be indicative of the effectiveness of stimuli. In particular embodiments, evaluations are calibrated to each subject and synchronized across subjects. In particular embodiments, templates are created for subjects to create a baseline for measuring pre and post stimulus differentials. According to various embodiments, stimulus generators are intelligent and adaptively modify specific parameters such as exposure length and duration for each subject being analyzed.
FIG. 1 illustrates one example of a system for evaluating stimulus materials including performing mirror neuron system analysis by using central nervous system, autonomic nervous system, and/or effector measures. According to various embodiments, the mirror neuron system analysis system includes a stimulus presentation device 101. In particular embodiments, the stimulus presentation device 101 is merely a display, monitor, screen, etc., that displays stimulus material to a user. The stimulus material may be a media clip, a game, an offer, a performance, a movie, an audio presentation, and may even involve particular tastes, smells, textures and/or sounds. According to various embodiments, the stimulus materials includes a human-like entity such as a person, face, arm, etc., performing an action such as frowning, lifting, running, purchasing, grabbing, etc. The stimuli can involve a variety of senses and occur with or without human supervision. Continuous and discrete modes are supported. According to various embodiments, the stimulus presentation device 101 also has protocol generation capability to allow intelligent customization of stimuli.
According to various embodiments, stimulus presentation device 101 could include devices such as televisions, cable consoles, computers and monitors, projection systems, display devices, speakers, tactile surfaces, etc., for presenting the stimuli including but not limited to advertising and entertainment from different networks, local networks, cable channels, syndicated sources, websites, internet content aggregators, portals, service providers, etc.
According to various embodiments, the subjects 103 are connected to data collection devices 105. The data collection devices 105 may include a variety of neuro-response measurement mechanisms including neurological and neurophysiological measurements systems such as EEG, EOG, MEG, EKG, pupillary dilation, eye tracking, facial emotion encoding, and reaction time devices, etc. According to various embodiments, neuro-response data includes central nervous system, autonomic nervous system, and effector data. In particular embodiments, the data collection devices 105 include EEG 111, EOG 113, and fMRI 115. In some instances, only a single data collection device such as EEG is used. Data collection may proceed with or without human supervision. According to various embodiments, EEG data is collected from electrodes placed near the inferior frontal lobe and the posterior parietal lobe before and after a subject is present with material showing human activity.
The data collection device 105 collects neuro-response data from multiple sources. This includes a combination of devices such as central nervous system sources (EEG), autonomic nervous system sources (GSR, EKG, pupillary dilation), and effector sources (EOG, eye tracking, facial emotion encoding, reaction time). In particular embodiments, data collected is digitally sampled and stored for later analysis. In particular embodiments, the data collected could be analyzed in real-time. According to particular embodiments, the digital sampling rates are adaptively chosen based on the neurophysiological and neurological data being measured.
In one particular embodiment, the mirror neuron system analysis system includes EEG 111 measurements made using scalp level electrodes, EOG 113 measurements made using shielded electrodes to track eye data, fMRI 115 measurements performed using a differential measurement system, a facial muscular measurement through shielded electrodes placed at specific locations on the face, and a facial affect graphic and video analyzer adaptively derived for each individual.
In particular embodiments, the data collection devices are clock synchronized with a stimulus presentation device 101. In particular embodiments, the data collection devices 105 also include a condition evaluation subsystem that provides auto triggers, alerts and status monitoring and visualization components that continuously monitor the status of the subject, data being collected, and the data collection instruments. The condition evaluation subsystem may also present visual alerts and automatically trigger remedial actions. According to various embodiments, the data collection devices include mechanisms for not only monitoring subject neuro-response to stimulus materials, but also include mechanisms for identifying and monitoring the stimulus materials. For example, data collection devices 105 may be synchronized with a set-top box to monitor channel changes. In other examples, data collection devices 105 may be directionally synchronized to monitor when a subject is no longer paying attention to stimulus material. In still other examples, the data collection devices 105 may receive and store stimulus material generally being viewed by the subject, whether the stimulus is a program, a commercial, a game, or a scene outside a window. The data collected allows analysis of neuro-response information and correlation of the information to actual stimulus material and not mere subject distractions.
According to various embodiments, the mirror neuron system analysis system also includes a data cleanser device 121. In particular embodiments, the data cleanser device 121 filters the collected data to remove noise, artifacts, and other irrelevant data using fixed and adaptive filtering, weighted averaging, advanced component extraction (like PCA, ICA), vector and component separation methods, etc. This device cleanses the data by removing both exogenous noise (where the source is outside the physiology of the subject, e.g. a phone ringing while a subject is viewing a video) and endogenous artifacts (where the source could be neurophysiological, e.g. muscle movements, eye blinks, etc.).
The artifact removal subsystem includes mechanisms to selectively isolate and review the response data and identify epochs with time domain and/or frequency domain attributes that correspond to artifacts such as line frequency, eye blinks, and muscle movements. The artifact removal subsystem then cleanses the artifacts by either omitting these epochs, or by replacing these epoch data with an estimate based on the other clean data (for example, an EEG nearest neighbor weighted averaging approach).
According to various embodiments, the data cleanser device 121 is implemented using hardware, firmware, and/or software. It should be noted that although a data cleanser device 121 is shown located after a data collection device 105, the data cleanser device 121 like other components may have a location and functionality that varies based on system implementation. For example, some systems may not use any automated data cleanser device whatsoever while in other systems, data cleanser devices may be integrated into individual data collection devices.
In particular embodiments, a survey and interview system collects and integrates user survey and interview responses to combine with neuro-response data to more effectively select content for delivery. According to various embodiments, the survey and interview system obtains information about user characteristics such as age, gender, income level, location, interests, buying preferences, hobbies, etc. The survey and interview system can also be used to obtain user responses about particular pieces of stimulus material.
According to various embodiments, the mirror neuron system analysis system includes a mirror neuron system data analyzer 123 associated with the data cleanser 121. The data analyzer 123 uses a variety of mechanisms to analyze underlying data in the system to determine mirror neuron system activity. According to various embodiments, the mirror neuron data analyzer 123 measures mu, beta, and gamma rhythms from scalp level electrodes placed near the inferior frontal lobe and the posterior parietal lobe. Increases in gamma rhythms have been determined to correspond to significant mirror neuron system activity. Suppression of mu and beta rhythms have been determined to correspond to lack of mirror neuron system activity. The mirror neuron system data analyzer may also analyze other data to obtain an aggregate measure of stimulus effectiveness.
According to various embodiments, neurological and neuro-physiological signatures are measured using time domain analyses and frequency domain analyses. Such analyses use parameters that are common across individuals as well as parameters that are unique to each individual. The analyses could also include statistical parameter extraction and fuzzy logic based attribute estimation from both the time and frequency components of the synthesized response.
In some examples, statistical parameters used in a blended effectiveness estimate include evaluations of skew, peaks, first and second moments, distribution, as well as fuzzy estimates of attention, emotional engagement and memory retention responses.
According to various embodiments, the mirror neuron system data analyzer 123 may include an intra-modality response synthesizer and a cross-modality response synthesizer. In particular embodiments, the intra-modality response synthesizer is configured to customize and extract the independent neurological and neurophysiological parameters for each individual in each modality and blend the estimates within a modality analytically to elicit an enhanced response to the presented stimuli. In particular embodiments, the intra-modality response synthesizer also aggregates data from different subjects in a dataset.
According to various embodiments, the cross-modality response synthesizer or fusion device blends different intra-modality responses, including raw signals and signals output. The combination of signals enhances the measures of effectiveness within a modality. The cross-modality response fusion device can also aggregate data from different subjects in a dataset.
According to various embodiments, the mirror neuron data analyzer 123 also includes a composite enhanced effectiveness estimator (CEEE) that combines the enhanced responses and estimates from each modality to provide a blended estimate of the effectiveness. In particular embodiments, blended estimates are provided for each exposure of a subject to stimulus materials. The blended estimates are evaluated over time to assess resonance characteristics. According to various embodiments, numerical values are assigned to each blended estimate. The numerical values may correspond to the intensity of neuro-response measurements, the significance of peaks, the change between peaks, etc. Higher numerical values may correspond to higher significance in neuro-response intensity. Lower numerical values may correspond to lower significance or even insignificant neuro-response activity. In other examples, multiple values are assigned to each blended estimate. In still other examples, blended estimates of neuro-response significance are graphically represented to show changes after repeated exposure.
According to various embodiments, a mirror neuron data analyzer 123 passes data to a resonance estimator that assesses and extracts resonance patterns. In particular embodiments, the resonance estimator determines entity positions in various stimulus segments and matches position information with eye tracking paths while correlating saccades with neural assessments of attention, memory retention, and emotional engagement. In particular embodiments, the resonance estimator stores data in the priming repository system. As with a variety of the components in the system, various repositories can be co-located with the rest of the system and the user, or could be implemented in remote locations.
Data from the mirror neuron data analyzer 123 is used to generate a propensity to act index 125. According to various embodiments, the propensity to act index 125 is associated with an individuals propensity to imitate, learn, or perform observed actions done by another. In some examples, the propensity to act index 125 is a calibrated measure of gamma rhythms divided by either mu or beta rhythms. In particular embodiments, the index is normalized based on demographic characteristics such as gender.
FIG. 2 illustrates examples of data models that may be user in a mirror neuron system analysis system. According to various embodiments, a stimulus attributes data model 201 includes a channel 203, media type 205, time span 207, audience 209, and demographic information 211. A stimulus purpose data model 213 may include intents 215 and objectives 217. According to various embodiments, stimulus purpose data model 213 also includes spatial and temporal information 219 about entities and emerging relationships between entities.
According to various embodiments, another stimulus attributes data model 221 includes creation attributes 223, ownership attributes 225, broadcast attributes 227, and statistical, demographic and/or survey based identifiers 229 for automatically integrating the neuro-physiological and neuro-behavioral response with other attributes and meta-information associated with the stimulus.
According to various embodiments, a stimulus priming data model 231 includes fields for identifying advertisement breaks 233 and scenes 235 that can be associated with various priming levels 237 and audience resonance measurements 239. In particular embodiments, the data model 231 provides temporal and spatial information for ads, scenes, events, locations, etc. that may be associated with priming levels and audience resonance measurements. In some examples, priming levels for a variety of products, services, offerings, etc. are correlated with temporal and spatial information in source material such as a movie, billboard, advertisement, commercial, store shelf, etc. In some examples, the data model associates with each second of a show a set of meta-tags for pre-break content indicating categories of products and services that are primed. The level of priming associated with each category of product or service at various insertions points may also be provided. Audience resonance measurements and maximal audience resonance measurements for various scenes and advertisement breaks may be maintained and correlated with sets of products, services, offerings, etc.
The priming and resonance information may be used to select stimulus content suited for particular levels of priming and resonance.
FIG. 3 illustrates examples of data models that can be used for storage of information associated with tracking and measurement of resonance. According to various embodiments, a dataset data model 301 includes an experiment name 303 and/or identifier, client attributes 305, a subject pool 307, logistics information 309 such as the location, date, and time of testing, and stimulus material 311 including stimulus material attributes.
In particular embodiments, a subject attribute data model 315 includes a subject name 317 and/or identifier, contact information 321, and demographic attributes 319 that may be useful for review of neurological and neuro-physiological data. Some examples of pertinent demographic attributes include marriage status, employment status, occupation, household income, household size and composition, ethnicity, geographic location, sex, race. Other fields that may be included in data model 315 include subject preferences 323 such as shopping preferences, entertainment preferences, and financial preferences. Shopping preferences include favorite stores, shopping frequency, categories shopped, favorite brands. Entertainment preferences include network/cable/satellite access capabilities, favorite shows, favorite genres, and favorite actors. Financial preferences include favorite insurance companies, preferred investment practices, banking preferences, and favorite online financial instruments. A variety of product and service attributes and preferences may also be included. A variety of subject attributes may be included in a subject attributes data model 315 and data models may be preset or custom generated to suit particular purposes.
According to various embodiments, data models for neuro-feedback association 325 identify experimental protocols 327, modalities included 329 such as EEG, EOG, GSR, surveys conducted, and experiment design parameters 333 such as segments and segment attributes. Other fields may include experiment presentation scripts, segment length, segment details like stimulus material used, inter-subject variations, intra-subject variations, instructions, presentation order, survey questions used, etc. Other data models may include a data collection data model 337. According to various embodiments, the data collection data model 337 includes recording attributes 339 such as station and location identifiers, the data and time of recording, and operator details. In particular embodiments, equipment attributes 341 include an amplifier identifier and a sensor identifier.
Modalities recorded 343 may include modality specific attributes like EEG cap layout, active channels, sampling frequency, and filters used. EOG specific attributes include the number and type of sensors used, location of sensors applied, etc. Eye tracking specific attributes include the type of tracker used, data recording frequency, data being recorded, recording format, etc. According to various embodiments, data storage attributes 345 include file storage conventions (format, naming convention, dating convention), storage location, archival attributes, expiry attributes, etc.
A preset query data model 349 includes a query name 351 and/or identifier, an accessed data collection 353 such as data segments involved (models, databases/cubes, tables, etc.), access security attributes 355 included who has what type of access, and refresh attributes 357 such as the expiry of the query, refresh frequency, etc. Other fields such as push-pull preferences can also be included to identify an auto push reporting driver or a user driven report retrieval system.
FIG. 4 illustrates examples of queries that can be performed to obtain data associated with mirror neuron system analysis. According to various embodiments, queries are defined from general or customized scripting languages and constructs, visual mechanisms, a library of preset queries, diagnostic querying including drill-down diagnostics, and eliciting what if scenarios. According to various embodiments, subject attributes queries 415 may be configured to obtain data from a neuro-informatics repository using a location 417 or geographic information, session information 421 such as testing times and dates, and demographic attributes 419. Demographics attributes include household income, household size and status, education level, age of kids, etc.
Other queries may retrieve stimulus material based on shopping preferences of subject participants, countenance, physiological assessment, completion status. For example, a user may query for data associated with product categories, products shopped, shops frequented, subject eye correction status, color blindness, subject state, signal strength of measured responses, alpha frequency band ringers, muscle movement assessments, segments completed, etc. Experimental design based queries 425 may obtain data from a neuro-informatics repository based on experiment protocols 427, product category 429, surveys included 431, and stimulus provided 433. Other fields that may be used include the number of protocol repetitions used, combination of protocols used, and usage configuration of surveys.
Client and industry based queries may obtain data based on the types of industries included in testing, specific categories tested, client companies involved, and brands being tested. Response assessment based queries 437 may include attention scores 439, emotion scores, 441, retention scores 443, and effectiveness scores 445. Such queries may obtain materials that elicited particular scores. In particular embodiments, propensity queries 447 may include aggregate propensity to act 449 queries, propensity to reach 451, learning index 453, and empathy index 455 queries.
Response measure profile based queries may use mean measure thresholds, variance measures, number of peaks detected, etc. Group response queries may include group statistics like mean, variance, kurtosis, p-value, etc., group size, and outlier assessment measures. Still other queries may involve testing attributes like test location, time period, test repetition count, test station, and test operator fields. A variety of types and combinations of types of queries can be used to efficiently extract data.
FIG. 5 illustrates examples of reports that can be generated. According to various embodiments, client assessment summary reports 501 include effectiveness measures 503, component assessment measures 505, and resonance measures 507. Effectiveness assessment measures include composite assessment measure(s), industry/category/client specific placement (percentile, ranking, etc.), actionable grouping assessment such as removing material, modifying segments, or fine tuning specific elements, etc, and the evolution of the effectiveness profile over time. In particular embodiments, component assessment reports include component assessment measures like attention, emotional engagement scores, percentile placement, ranking, etc. Component profile measures include time based evolution of the component measures and profile statistical assessments. According to various embodiments, reports include the number of times material is assessed, attributes of the multiple presentations used, evolution of the response assessment measures over the multiple presentations, and usage recommendations.
According to various embodiments, client cumulative reports 511 include media grouped reporting 513 of all stimulus assessed, campaign grouped reporting 515 of stimulus assessed, and time/location grouped reporting 517 of stimulus assessed. According to various embodiments, industry cumulative and syndicated reports 521 include aggregate assessment responses measures 523, top performer lists 525, bottom performer lists 527, outliers 529, and trend reporting 531. In particular embodiments, tracking and reporting includes specific products, categories, companies, brands. According to various embodiments, propensity reports 533 are also generated. Propensity reports may include propensity to act 535, propensity to reach 537, learning index 539, and empathy index 541 reports.
FIG. 6 illustrates one example of mirror neuron system analysis. At 601, stimulus material is provided to multiple subjects. According to various embodiments, stimulus includes streaming video depicting a non-human like entity such as a stick figure, machine, or object performing an action. In particular embodiments, subjects view stimulus in their own homes in group or individual settings. In some examples, verbal and written responses are collected for use without neuro-response measurements. In other examples, verbal and written responses are correlated with neuro-response measurements. At 603, subject neuro-response measurements are collected using a variety of modalities, such as EEG, MEG, etc. At 605, data is passed through a data cleanser to remove noise and artifacts that may make data more difficult to interpret. According to various embodiments, the data cleanser removes EEG electrical activity associated with blinking and other endogenous/exogenous artifacts.
According to various embodiments, data analysis is performed to detect mu and/or beta rhythm suppression at 607, particularly in areas associated with the mirror neuron system. Data is also analyzed to detect increases in gamma rhythms at 609, again particularly in areas associated with the mirror neuron system. At 611, a mirror neuron system baseline is generated. Mirror neuron system baselines may be generated on an individual, subgroup, and group basis. At 613, integrated data is sent to a mirror neuron system analyzer repository 619. The integrated data may include subject responses and resulting behavior information from the subject. The data sent to the mirror neuron system analyzer repository 619 may be used to provide a baseline for further individual, subgroup, and group measurements of mirror neuron system activity detected in subjects exposed to stimulus material.
According to various embodiments, neuro-response data is analyzed to not only measure mirror neuron system activity in response to stimulus but to also determine other measures of stimulus effectiveness. A variety of mechanisms can be used to perform data analysis and to analyze stimulus material effectiveness. EEG response data can be synthesized to provide an enhanced assessment of effectiveness. According to various embodiments, EEG measures electrical activity resulting from thousands of simultaneous neural processes associated with different portions of the brain. EEG data can be classified in various bands. According to various embodiments, brainwave frequencies include delta, theta, alpha, beta, and gamma frequency ranges. Delta waves are classified as those less than 4 Hz and are prominent during deep sleep. Theta waves have frequencies between 3.5 to 7.5 Hz and are associated with memories, attention, emotions, and sensations. Theta waves are typically prominent during states of internal focus.
Alpha frequencies reside between 7.5 and 13 Hz and typically peak around 10 Hz. Alpha waves are prominent during states of relaxation. Beta waves have a frequency range between 14 and 30 Hz. Beta waves are prominent during states of motor control, long range synchronization between brain areas, analytical problem solving, judgment, and decision making. Gamma waves occur between 30 and 60 Hz and are involved in binding of different populations of neurons together into a network for the purpose of carrying out a certain cognitive or motor function, as well as in attention and memory. Because the skull and dermal layers attenuate waves in this frequency range, brain waves above 75-80 Hz are difficult to detect and are often not used for stimuli response assessment.
However, the techniques and mechanisms of the present invention recognize that analyzing high gamma band (kappa-band: Above 60 Hz) measurements, in addition to theta, alpha, beta, and low gamma band measurements, enhances neurological attention, emotional engagement and retention component estimates. In particular embodiments, EEG measurements including difficult to detect high gamma or kappa band measurements are obtained, enhanced, and evaluated. Subject and task specific signature sub-bands in the theta, alpha, beta, gamma and kappa bands are identified to provide enhanced response estimates. According to various embodiments, high gamma waves (kappa-band) above 80 Hz (typically detectable with sub-cranial EEG and/or magnetoencephalograophy) can be used in inverse model-based enhancement of the frequency responses to the stimuli.
Various embodiments of the present invention recognize that particular sub-bands within each frequency range have particular prominence during certain activities. A subset of the frequencies in a particular band is referred to herein as a sub-band. For example, a sub-band may include the 40-45 Hz range within the gamma band. In particular embodiments, multiple sub-bands within the different bands are selected while remaining frequencies are band pass filtered. In particular embodiments, multiple sub-band responses may be enhanced, while the remaining frequency responses may be attenuated.
An information theory based band-weighting model is used for adaptive extraction of selective dataset specific, subject specific, task specific bands to enhance the effectiveness measure. Adaptive extraction may be performed using fuzzy scaling. Stimuli can be presented and enhanced measurements determined multiple times to determine the variation profiles across multiple presentations. Determining various profiles provides an enhanced assessment of the primary responses as well as the longevity (wear-out) of the marketing and entertainment stimuli. The synchronous response of multiple individuals to stimuli presented in concert is measured to determine an enhanced across subject synchrony measure of effectiveness. According to various embodiments, the synchronous response may be determined for multiple subjects residing in separate locations or for multiple subjects residing in the same location.
Although a variety of synthesis mechanisms are described, it should be recognized that any number of mechanisms can be applied—in sequence or in parallel with or without interaction between the mechanisms.
Although intra-modality synthesis mechanisms provide enhanced significance data, additional cross-modality synthesis mechanisms can also be applied. A variety of mechanisms such as EEG, Eye Tracking, GSR, EOG, and facial emotion encoding are connected to a cross-modality synthesis mechanism. Other mechanisms as well as variations and enhancements on existing mechanisms may also be included. According to various embodiments, data from a specific modality can be enhanced using data from one or more other modalities. In particular embodiments, EEG typically makes frequency measurements in different bands like alpha, beta and gamma to provide estimates of significance. However, the techniques of the present invention recognize that significance measures can be enhanced further using information from other modalities.
For example, facial emotion encoding measures can be used to enhance the valence of the EEG emotional engagement measure. EOG and eye tracking saccadic measures of object entities can be used to enhance the EEG estimates of significance including but not limited to attention, emotional engagement, and memory retention. According to various embodiments, a cross-modality synthesis mechanism performs time and phase shifting of data to allow data from different modalities to align. In some examples, it is recognized that an EEG response will often occur hundreds of milliseconds before a facial emotion measurement changes. Correlations can be drawn and time and phase shifts made on an individual as well as a group basis. In other examples, saccadic eye movements may be determined as occurring before and after particular EEG responses. According to various embodiments, time corrected GSR measures are used to scale and enhance the EEG estimates of significance including attention, emotional engagement and memory retention measures.
Evidence of the occurrence or non-occurrence of specific time domain difference event-related potential components (like the DERP) in specific regions correlates with subject responsiveness to specific stimulus. According to various embodiments, ERP measures are enhanced using EEG time-frequency measures (ERPSP) in response to the presentation of the marketing and entertainment stimuli. Specific portions are extracted and isolated to identify ERP, DERP and ERPSP analyses to perform. In particular embodiments, an EEG frequency estimation of attention, emotion and memory retention (ERPSP) is used as a co-factor in enhancing the ERP, DERP and time-domain response analysis.
EOG measures saccades to determine the presence of attention to specific objects of stimulus. Eye tracking measures the subject's gaze path, location and dwell on specific objects of stimulus. According to various embodiments, EOG and eye tracking is enhanced by measuring the presence of lambda waves (a neurophysiological index of saccade effectiveness) in the ongoing EEG in the occipital and extra striate regions, triggered by the slope of saccade-onset to estimate the significance of the EOG and eye tracking measures. In particular embodiments, specific EEG signatures of activity such as slow potential shifts and measures of coherence in time-frequency responses at the Frontal Eye Field (FEF) regions that preceded saccade-onset are measured to enhance the effectiveness of the saccadic activity data.
According to various embodiments, facial emotion encoding uses templates generated by measuring facial muscle positions and movements of individuals expressing various emotions prior to the testing session. These individual specific facial emotion encoding templates are matched with the individual responses to identify subject emotional response. In particular embodiments, these facial emotion encoding measurements are enhanced by evaluating inter-hemispherical asymmetries in EEG responses in specific frequency bands and measuring frequency band interactions. The techniques of the present invention recognize that not only are particular frequency bands significant in EEG responses, but particular frequency bands used for communication between particular areas of the brain are significant. Consequently, these EEG responses enhance the EMG, graphic and video based facial emotion identification.
In some examples, post-stimulus versus pre-stimulus differential measurements of ERP time domain components in multiple regions of the brain (DERP) are measured at multiple regions of the brain. The differential measures give a mechanism for eliciting responses attributable to the stimulus. For example the messaging response attributable to an advertisement or the brand response attributable to multiple brands is determined using pre-resonance and post-resonance estimates
Target versus distracter stimulus differential responses are determined for different regions of the brain (DERP). Event related time-frequency analysis of the differential response (DERPSPs) are used to assess the attention, emotion and memory retention measures across multiple frequency bands. According to various embodiments, the multiple frequency bands include theta, alpha, beta, gamma and high gamma or kappa.
FIG. 7 illustrates an example of a technique for mirror neuron system analysis. At 701, stimulus material is provided to multiple subjects. According to various embodiments, stimulus includes streaming video depicting a human like entity such as a human hand, face, semi-realistic animation, etc., performing an action. In particular embodiments, subjects view stimulus in their own homes in group or individual settings. In some examples, verbal and written responses are collected for use without neuro-response measurements. In other examples, verbal and written responses are correlated with neuro-response measurements. At 703, subject neuro-response measurements are collected using a variety of modalities, such as EEG, MEG, etc. At 705, data is passed through a data cleanser to remove noise and artifacts that may make data more difficult to interpret. According to various embodiments, the data cleanser removes EEG electrical activity associated with blinking and other endogenous/exogenous artifacts.
According to various embodiments, data analysis is performed to detect mu and/or beta rhythm suppression at 707, particularly in areas associated with the mirror neuron system. Data is also analyzed to detect increases in gamma rhythms at 709, again particularly in areas associated with the mirror neuron system. At 711, a mirror neuron system baseline along with gamma and beta/mu rhythms can be used to generate a propensity to act index. According to various embodiments, a propensity to act index corresponds to gamma rhythms divided by either beta or mu rhythms. In some examples, survey responses and resulting behavior information is integrated at 713. It should be noted that propensity to reach, learning index, and empathy index measures can also be generated using gamma, beta, mu, and baseline measurements along with resulting behavior and survey information. At 717, multiple trials are performed to enhance measurements. At 719, data is sent to a mirror neuron system analyzer repository.
According to various embodiments, various mechanisms such as the data collection mechanisms, the intra-modality synthesis mechanisms, cross-modality synthesis mechanisms, etc. are implemented on multiple devices. However, it is also possible that the various mechanisms be implemented in hardware, firmware, and/or software in a single system. FIG. 8 provides one example of a system that can be used to implement one or more mechanisms. For example, the system shown in FIG. 8 may be used to implement a resonance measurement system.
According to particular example embodiments, a system 800 suitable for implementing particular embodiments of the present invention includes a processor 801, a memory 803, an interface 811, and a bus 815 (e.g., a PCI bus). When acting under the control of appropriate software or firmware, the processor 801 is responsible for such tasks such as pattern generation. Various specially configured devices can also be used in place of a processor 801 or in addition to processor 801. The complete implementation can also be done in custom hardware. The interface 811 is typically configured to send and receive data packets or data segments over a network. Particular examples of interfaces the device supports include host bus adapter (HBA) interfaces, Ethernet interfaces, frame relay interfaces, cable interfaces, DSL interfaces, token ring interfaces, and the like.
According to particular example embodiments, the system 800 uses memory 803 to store data, algorithms and program instructions. The program instructions may control the operation of an operating system and/or one or more applications, for example. The memory or memories may also be configured to store received data and process received data.
Because such information and program instructions may be employed to implement the systems/methods described herein, the present invention relates to tangible, machine readable media that include program instructions, state information, etc. for performing various operations described herein. Examples of machine-readable media include, but are not limited to, magnetic media such as hard disks, floppy disks, and magnetic tape; optical media such as CD-ROM disks and DVDs; magneto-optical media such as optical disks; and hardware devices that are specially configured to store and perform program instructions, such as read-only memory devices (ROM) and random access memory (RAM). Examples of program instructions include both machine code, such as produced by a compiler, and files containing higher level code that may be executed by the computer using an interpreter.
Although the foregoing invention has been described in some detail for purposes of clarity of understanding, it will be apparent that certain changes and modifications may be practiced within the scope of the appended claims. Therefore, the present embodiments are to be considered as illustrative and not restrictive and the invention is not to be limited to the details given herein, but may be modified within the scope and equivalents of the appended claims.

## Claims

1. A method, comprising:
analyzing, using a processor, neuro-response data from a subject exposed to first stimulus material, wherein the neuro-response data includes data obtained from areas of a brain of the subject associated with a mirror neuron system, and the neuro-response data includes gamma band data and mu band data;
identifying at least one of (1) an increase in mirror neuron activity based on an increase in gamma band data and a decrease in mu band data or (2) a decrease in mirror neuron activity based on a decrease in gamma band data and an increase in mu band data; and
generating, using the processor, a propensity to act index indicating at least one of (a) that the subject is likely to take an action based on the increase in the mirror neuron activity or (b) that the subject is not likely to take the action based on the decrease in the mirror neuron activity.

2. The method of claim 1, wherein the gamma band data comprises gamma rhythms.

3. The method of claim 1, wherein the neuro-response data includes beta band data and the propensity to act index is further based on a ratio of the gamma band data to the beta band data, and the beta band data comprises beta rhythms.

4. The method of claim 1, wherein the mu band data comprises mu rhythms.

5. The method of claim 1, wherein the propensity to act is further based on a ratio of the gamma band data to the mu band data.

6. The method of claim 1, wherein the neuron-response data is obtained using electroencephalography.

7. The method of claim 1, wherein the neuro-response data is obtained using magnetoencephalography.

8. The method of claim 1 further comprising generating a baseline by analyzing second neuro-response data gathered from the subject while exposed to second stimulus material before the subject is exposed to the first stimulus material.

9. The method of claim 1, wherein the propensity to act index is calibrated based on a demographic group.

10. The method of claim 9, wherein the propensity to act index is calibrated based on a gender.

11. The method of claim 1 further comprising generating a propensity to reach index based on the neuro-response data.

12. The method of claim 1 further comprising generating a learning index based on the neuro-response data.

13. The method of claim 1 further comprising generating an empathy index based on the neuro-response data.

14. A system, comprising:
a data collector to obtain neuro-response data from a subject exposed to first stimulus material, wherein the neuro-response data includes data obtained from areas of a brain of the subject associated with a mirror neuron system, the neuro-response data including gamma band data and mu band data; and
a data analyzer to:
identify at least one of (1) an increase in mirror neuron activity based on (a) an increase in gamma band data and (b) a decrease in mu band data or (2) a decrease in mirror neuron activity based on (a) a decrease in gamma band data and (b) an increase in mu band data; and
generate a propensity to act index indicating at least one of (1) that the subject is likely to take an action based on the increase in the mirror neuron activity or (2) that the subject is not likely to take the action based on the decrease in the mirror neuron activity.

15. The system of claim 14, wherein the gamma band data comprises gamma rhythms.

16. The system of claim 14, wherein the neuro-response data includes beta band data and the data analyzer is to generate the propensity to act index based on a ratio of the gamma band data to the beta band data, the beta band data comprising beta rhythms.

17. The system of claim 14, wherein the mu band data comprises mu rhythms.

18. The system of claim 14, wherein the data analyzer is to generate the propensity to act index based on a ratio of the gamma band data to the mu band data.

19. The system of claim 14, wherein the data collector is to obtain the neuron-response data using electroencephalography.

20. The system of claim 14, wherein the data analyzer is to generate a baseline by analyzing second neuro-response data gathered from the subject while exposed to second stimulus material before the subject is exposed to the first stimulus material.

21. The system of claim 14, wherein the data analyzer is to calibrate the propensity to act index based on a demographic group.

22. The system of claim 21, wherein the data analyzer is to calibrate the propensity to act index based on a gender.

23. The system of claim 14, wherein the data analyzer is to generate a propensity to reach index based on the neuro-response data.

24. The system of claim 14, wherein the data analyzer is to generate a learning index based on the neuro-response data.

25. The system of claim 14, wherein the data analyzer is to generate an empathy index based on the neuro-response data.

26. A tangible machine readable storage device or storage disc comprising instructions which, when executed, cause a machine to at least:
access neuro-response data from a subject exposed to stimulus material, wherein the neuro-response data includes data obtained from areas of a brain of the subject associated with a mirror neuron system, the neuro-response data including gamma band data and mu band data;
identify at least one of (1) an increase in mirror neuron activity based on (a) an increase in gamma band data and (b) a decrease in mu band data or (2) a decrease in mirror neuron activity based on (a) a decrease in gamma band data and (b) an increase in mu band data; and
generate a propensity to act index indicating at least one of (1) that the subject is likely to take an action based on the increase in the mirror neuron activity or (2) that the subject is not likely to take the action based on the decrease in the mirror neuron activity.