36758 Federal Register / Vol. 86, No. 131 / Tuesday, July 13, 2021 / Notices 

Disclosure Agreement will be required 

to receive copies of unpublished patent 

applications. 

SUPPLEMENTARY INFORMATION: 

Technology description follows. 

Mononegavirales Vectors Expressing 

Chimeric Antigens 

Description of Technology 

Human respiratory syncytial virus 

(RSV) continues to be the leading viral 

cause of severe acute lower respiratory 

tract disease in infants and children 

worldwide, and also is an important 

cause of morbidity and mortality in the 

elderly. A licensed vaccine or antiviral 

drug suitable for routine use remains 

unavailable. This invention relates to 

the use of murine pneumonia virus 

(MPV—previously known as pneumonia 

virus of mice, PVM—of family 

Pneumoviridae) as a vaccine vector 

expressing the RSV fusion protein F, the 

most important protective antigen of 

RSV. MPV is not a human pathogen and 

is not restricted by immunity to 

common human viruses. MPV replicates 

in the superficial epithelial cells of the 

respiratory mucosa and is expected to 

be attenuated in humans based on the 

strong host range restriction observed in 

non-human primates. To generate these 

MPV/RSV vector vaccine candidates, 

the RSV F ORF was codon optimized, 

placed under the control of MPV 

transcription signals, and inserted at the 

first (rMPV–F1), third (rMPV29 F3), or 

fourth (rMPV–F4) gene position of a 

version of the MPV genome that 

contained a codon-pair optimized L 

polymerase gene. The recovered viruses 

replicated in vitro as efficiently as the 

empty vector, with stable expression of 

RSV F protein. Replication and 

immunogenicity of rMPV–F1 and 

rMPV–F3 were evaluated in rhesus 

macaques following administration by 

the combined intranasal and 

intratracheal routes. Both viruses 

replicated at low levels in the upper and 

lower respiratory tract, maintained 

stable RSV F expression, and induced 

similarly high levels of RSVneutralizing serum antibodies that 

reached peak titers by fourteen (14) days 

post-vaccination. Thus, rMPV provides 

a highly attenuated yet immunogenic 

vector for the expression of RSV F 

protein, with potential application in 

RSV-naı ̈ve and RSV-experienced 

populations. RSV F was expressed in 

the wild-type form, but can readily be 

engineered to be stabilized in the highly 

immunogenic prefusion form, as has 

been done with parainfluenza virus 

vectors. 

The invention relates to live, chimeric 

non-human Mononegavirales vectors 

that allow a cell to express at least one 

protein from at least one human 

pathogen as well as compositions 

comprising the vectors, methods and 

kits for eliciting an immune response in 

a host, and methods of making the 

vectors. 

This technology is available for 

licensing for commercial development 

in accordance with 35 U.S.C. 209 and 37 

CFR part 404, as well as for further 

development and evaluation under a 

research collaboration. 

Potential Commercial Applications 

• Viral diagnostics 

• Vaccine research 

Competitive Advantages 

• Ease of manufacture 

• Multivalent live attenuated vaccines 

• B cell and T cell activation 

• Low-cost vaccines 

Development Stage 

• In vivo data assessment (animal) 

Inventors: Shirin Munir (NIAID), 

Linda Brock (NIAID), Ursula Buchholz 

(NIAID), Peter Collins (NIAID). 

Intellectual Property: HHS Reference 

No. E–018–2018/0—U.S. Provisional 

Application No. 62/661,320, filed April 

23, 2018 (expired), PCT Patent 

Application No. PCT/US2019/028771, 

filed April 23, 2019 (expired), 

Taiwanese Patent Application No. 

108114132, filed April 23, 2019 

(pending), Brazilian Patent Application 

No. BR112020021652–6, filed October 

22, 2020 (pending), Australian Patent 

Application No. 2019261570, filed 

October 21, 2020 (pending), Canadian 

Patent Application No. 3097888, filed 

October 20, 2020 (pending), Chinese 

Patent Application No. 201980039372.6, 

filed December 15, 2020 (pending), 

European Patent Application No. 

19729386.3, filed November 13, 2020 

(pending), Indian Patent Application 

No. 20204706248, filed October 23, 

2020, Japanese Patent Application No. 

2020–558967, filed October 22, 2020, 

South Korean Patent Application No. 

2020–7033157, filed November 18, 

2020, and United States Patent 

Application No. 17/049,916, filed 

October 22, 2020. 

Licensing Contact: Peter Soukas, J.D., 

301–496–2644; peter.soukas@nih.gov. 

Collaborative Research Opportunity: 

The National Institute of Allergy and 

Infectious Diseases is seeking statements 

of capability or interest from parties 

interested in collaborative research to 

further develop, evaluate or 

commercialize for development of a 

vaccine for respiratory or other 

infections. For collaboration 

opportunities, please contact Peter 

Soukas, J.D., 301–496–2644; 

peter.soukas@nih.gov. 

Dated: July 8, 2021. 

Anna V. Ganelina, 

Senior Technology Transfer and Patenting 

Specialist, Technology Transfer and 

Intellectual Property Office, National Institute 

of Allergy and Infectious Diseases. 

[FR Doc. 2021–14820 Filed 7–12–21; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HOMELAND 

SECURITY 

Transportation Security Administration 

Revision of Agency Information 

Collection Activity Under OMB Review: 

TSA Customer Comment Tools 

AGENCY: Transportation Security 

Administration, Homeland Security 

(DHS). 

ACTION: 30-Day notice. 

SUMMARY: This notice announces that 

the Transportation Security 

Administration (TSA) has forwarded the 

Information Collection Request (ICR), 

Office of Management and Budget 

(OMB) control number 1652–0030, 

abstracted below to OMB for a revision 

of the currently approved collection 

under the Paperwork Reduction Act 

(PRA). The ICR describes the nature of 

the information collection and its 

expected burden. This collection allows 

customers to provide feedback to TSA 

about their experiences with TSA’s 

processes and procedures, to request 

information or request assistance at the 

TSA checkpoint, and to report security 

threats and vulnerabilities. 

DATES: Send your comments by August 

12, 2021. A comment to OMB is most 

effective if OMB receives it within 30 

days of publication. 

ADDRESSES: Written comments and 

recommendations for the proposed 

information collection should be sent 

within 30 days of publication of this 

notice to www.reginfo.gov/public/do/ 

PRAMain. Find this particular 

information collection by selecting 

‘‘Currently under Review—Open for 

Public Comments’’ or by using the find 

function. 

FOR FURTHER INFORMATION CONTACT: 

Christina A. Walsh, TSA PRA Officer, 

Information Technology (IT), TSA–11, 

Transportation Security Administration, 

6595 Springfield Center Drive, 

Springfield, VA 20598–6011; telephone 

(571) 227–2062; email TSAPRA@

dhs.gov. 

SUPPLEMENTARY INFORMATION: TSA 

published a Federal Register notice, 


jbell on DSKJLSW7X2PROD with NOTICES
Federal Register / Vol. 86, No. 131 / Tuesday, July 13, 2021 / Notices 36759 

with a 60-day comment period soliciting 

comments, of the following collection of 

information on April 13, 2021 (86 FR 

19276). 

Comments Invited 

In accordance with the Paperwork 

Reduction Act of 1995 (44 U.S.C. 3501 

et seq.), an agency may not conduct or 

sponsor, and a person is not required to 

respond to, a collection of information 

unless it displays a valid OMB control 

number. The ICR documentation will be 

made available at http://

www.reginfo.gov upon its submission to 

OMB. Therefore, in preparation for 

OMB review and approval of the 

following information collection, TSA is 

soliciting comments to— 

(1) Evaluate whether the proposed 

information requirement is necessary for 

the proper performance of the functions 

of the agency, including whether the 

information will have practical utility; 

(2) Evaluate the accuracy of the 

agency’s estimate of the burden; 

(3) Enhance the quality, utility, and 

clarity of the information to be 

collected; and 

(4) Minimize the burden of the 

collection of information on those who 

are to respond, including using 

appropriate automated, electronic, 

mechanical, or other technological 

collection techniques or other forms of 

information technology. 

Information Collection Requirement 

Title: TSA Customer Comment Tools. 

Type of Request: Revision of a 

currently approved collection. 

OMB Control Number: 1652–0030. 

Forms(s): NA. 

Affected Public: Travelling public. 

Abstract: The TSA Contact Center 

(TCC) continues to serve as the main 

portal of communication for the 

traveling public. The public may contact 

the TCC via email or phone to request 

information, file a complaint—general 

or Civil Rights and Liberties, 

compliment, or provide general 

feedback. With over one million 

contacts per year, it is crucial for TSA 

to have the ability to capture this 

information. TSA’s online submission 

forms are readily available from the 

Customer Service portion of tsa.gov. The 

online forms are easy to use and offer 

several dropdown menu choices to 

reduce the burden on the public and 

increase the quality of data for TSA. 

Currently, there are four options for the 

online forms: Complaint and 

Compliment, Request for Assistance, 

Request for Information, and Security 

Issues. The online forms are easy to use 

and offer several dropdown menu 

choices to reduce the burden on the 

public and increase the quality of data 

for TSA. TCC provides a receipt to any 

person who submits an online form. 

TSA is revising the information 

collection, moving from four online 

forms to six electronic forms. The online 

form Complaint and Compliment has 

been broken into two separate distinct 

online forms. TSA PreCheckTM has been 

pulled out of the drop down menu of 

Complaint and given its own online 

form. Request for Assistance online 

form has been renamed TSA Cares. The 

6 online forms are as follows: 

• Complaint—passengers may 

provide a complaint regarding their 

experiences with TSA security 

procedures. Passengers may also use 

this form to file Disability or Civil 

Rights and Civil Liberties complaints. 

• TSA PreCheck—passengers may 

share concerns about not receiving TSA 

PreCheck on their boarding pass or 

other concerns. 

• Compliment—passengers may share 

how TSA exceeded their expectations. 

• Request for Information— 

passengers may submit an inquiry about 

TSA policies and procedures, such as 

traveling with medical conditions, 

prohibited & permitted items, security 

screening and more. 

• TSA Cares—passengers may request 

assistance through the TSA screening 

checkpoint. 

• Security Issue—passengers may 

identify and report suspicious activities 

and threats. The TCC provides a receipt 

to any person who submits an electronic 

form or email to TSA as required by 49 

CFR 1503.3(a). 

Also, TSA is changing the name of 

OMB control number 1652–0030 from 

‘‘TSA Customer Comment Card’’ to 

‘‘TSA Customer Comment Tools’’ to 

more accurately represent the 

information collection. In addition, TSA 

is making non-substantive changes to 

the paper comment card, updating the 

appearance—font, TSA insignia and 

spacing. 

Number of Respondents: An 

estimated 88,352 respondents annually. 

Estimated Annual Burden Hours: An 

estimated 7,518 hours annually. 

Christina A. Walsh, 

TSA Paperwork Reduction Act Officer, 

Information Technology. 

[FR Doc. 2021–14886 Filed 7–12–21; 8:45 am] 

BILLING CODE 9110–05–P 

DEPARTMENT OF THE INTERIOR 

Fish and Wildlife Service 

[FWS–HQ–MB–2021–N170; FF09M13200/ 

201/FXMB12330900000; OMB Control 

Number 1018–0172] 

Agency Information Collection 

Activities; Submission to the Office of 

Management and Budget for Review 

and Approval; Federal Migratory Bird 

Hunting and Conservation Stamp 

(Duck Stamp) and Junior Duck Stamp 

Contests 

AGENCY: Fish and Wildlife Service, 

Interior. 

ACTION: Notice of information collection; 

request for comment. 

SUMMARY: In accordance with the 

Paperwork Reduction Act of 1995 

(PRA), we, the U.S. Fish and Wildlife 

Service (Service), are proposing to 

renew an information collection with 

revisions. 

DATES: Interested persons are invited to 

submit comments on or before August 

12, 2021. 

ADDRESSES: Written comments and 

recommendations for the proposed 

information collection should be sent 

within 30 days of publication of this 

notice to www.reginfo.gov/public/do/ 

PRAMain. Find this particular 

information collection by clicking on 

the link ‘‘Currently under Review— 

Open for Public Comments’’ or by using 

the search function. Please provide a 

copy of your comments to the Service 

Information Collection Clearance 

Officer, U.S. Fish and Wildlife Service, 

MS: PRB/PERMA (JAO/3W), 5275 

Leesburg Pike, Falls Church, VA 22041– 

3803 (mail); or by email to Info_Coll@

fws.gov. Please reference OMB Control 

Number 1018–0172 in the subject line of 

your comments. 

FOR FURTHER INFORMATION CONTACT: 

Madonna L. Baucum, Service 

Information Collection Clearance 

Officer, by email at Info_Coll@fws.gov, 

or by telephone at (703) 358–2503. 

Individuals who are hearing or speech 

impaired may call the Federal Relay 

Service at 1–800–877–8339 for TTY 

assistance. You may also view the 

information collection request (ICR) at 

http://www.reginfo.gov/public/do/ 

PRAMain. 

SUPPLEMENTARY INFORMATION: In 

accordance with the Paperwork 

Reduction Act of 1995 (PRA, 44 U.S.C. 

3501 et seq.) and 5 CFR 1320.8(d)(1), we 

provide the general public and other 

Federal agencies with an opportunity to 

comment on new, proposed, revised, 

and continuing collections of 


jbell on DSKJLSW7X2PROD with NOTICES