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ARS Home Northeast Area Ithaca, New York Robert W. Holley Center for Agriculture & Health Plant, Soil and Nutrition Research Docs





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Dave Schneiderheadline bar Selected PublicationsPersonal BioCurriculum Vitae  Dave SchneiderComputational Biologistphone: (607) 254-4510fax: (607) 255-0323email: Dave.Schneider@ars.usda.gov My primary research interests are: the development of computational methods for the inference and modeling of gene regulation networks in prokaryotes;rational design of functional genomics experiments to maximize laboratory efficiency and thorough exploitation of the resulting data;laboratory and computational approaches to understanding the complex relationships between protein structure, dynamics, and function.  These efforts are all focused on understanding the biology of *Pseudomonas syringae*, a plant pathogen that affects many crops around the world. Most of our work is on *P. syringae*pv. *tomato*DC3000 because it can infect both tomato and *Arabidopsis thaliana*; a unique opportunity given the availability of the complete genomic sequences for both host and pathogen [Buell, et al 2003]. It is not surprising that the *A. thaliana-P. syringae*DC3000 system has emerged as the premier model for the study of gene regulation and molecular aspects of pathogenesis from the point of view of both host and pathogen.


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