Exhibit 21.1

ENTITIES OF ADVANCED MEDICAL OPTICS, INC.



|                                                     |  |                                      
|---------------------------------------------------- |  | -------------------------------------
|NAME OF SUBSIDIARY                                   |  | PLACE OF INCORPORATIONOR ORGANIZATION
|1. AMO Development, LLC                              |  | United States (Delaware)             
|2. AMO Holdings, Inc.                                |  | United States (Delaware)             
|3. AMO Manufacturing USA, LLC                        |  | United States (Delaware)             
|4. AMO Nominee Holdings, LLC                         |  | United States (Delaware)             
|5. AMO Sales and Service, Inc.                       |  | United States (Delaware)             
|6. AMO Spain Holdings, LLC                           |  | United States (Delaware)             
|7. AMO U.K. Holdings, LLC                            |  | United States (Delaware)             
|8. AMO US Holdings, Inc.                             |  | United States (Delaware)             
|9. AMO USA Sales Holdings, Inc.                      |  | United States (Delaware)             
|10. AMO USA, LLC                                     |  | United States (Delaware)             
|11. Integrated Surgical Solutions, LLC               |  | United States (Delaware)             
|12. Quest Vision Technology, Inc.                    |  | United States (California)           
|13. AMO WaveFront Sciences, LLC                      |  | United States (New Mexico)           
|14. Advanced Medical Optics Australia Pty Ltd.       |  | Australia                            
|15. AMO Belgium BVBA                                 |  | Belgium                              
|16. AMO Canada Company                               |  | Canada                               
|17. AMO Global Holdings                              |  | Cayman Islands                       
|18. AMO Ireland                                      |  | Cayman Islands                       
|19. AMO Puerto Rico Manufacturing, Inc.              |  | Cayman Islands                       
|20. VISX                                             |  | Cayman Islands                       
|21. AMO (Hangzhou) Co., Ltd.                         |  | China                                
|22. AMO (Shanghai) Medical Devices Trading Co., Ltd. |  | China                                
|23. AMO Denmark ApS                                  |  | Denmark                              
|24. AMO France SAS                                   |  | France                               
|25. AMO Germany GmbH                                 |  | Germany                              
|26. AMO Asia Limited                                 |  | Hong Kong                            
|27. Advanced Medical Optics India Private Limited    |  | India                                
|28. Allergan Trading International Limited           |  | Ireland                              
|29. AMO Ireland Export Ltd.                          |  | Ireland                              
|30. AMO International Holdings                       |  | Ireland                              
|31. AMO Ireland Finance                              |  | Ireland                              
|32. AMO Regional Holdings                            |  | Ireland (Non Resident)               
|33. AMO Italy SrL                                    |  | Italy                                
|34. AMO Japan KK                                     |  | Japan                                
|35. AMO Malta Limited                                |  | Malta                                
|36. AMO Netherlands BV                               |  | Netherlands                          
|37. AMO Groningen B.V.                               |  | Netherlands                          
|38. Advanced Medical Optics Norway ASA               |  | Norway                               
|39. AMO Singapore Pte. Ltd.                          |  | Singapore                            
|40. Advanced Medical Optics Spain S.L.               |  | Spain                                



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|                                       |  |               
|-------------------------------------- |  | --------------
|41. AMO Manufacturing Spain, S.L.      |  | Spain         
|42. Advanced Medical Optics Norden AB  |  | Sweden        
|43. Advanced Medical Optics Uppsala AB |  | Sweden        
|44. AMO Switzerland GmbH               |  | Switzerland   
|45. AMO United Kingdom, Ltd.           |  | United Kingdom