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USDA Researchers Use an Edible Blue-Green Algae to Protect Honey Bees Against Viruses Contact: Jessica Ryan Email: Jessica.Ryan@usda.gov **BATON ROUGE, La., March 19, 2024** – Scientists at the United States Department of Agriculture (USDA)’s Agricultural Research Service (ARS) developed an edible antiviral treatment that can be used to protect honey bees against Deformed Wing Virus (DWV) and other viruses, according to a recent study published in *Sustainable Agriculture*. Honey bees are important agricultural pollinators. However, viruses, including DWV, are linked to the deaths of millions of colonies worldwide. DWV, like other viruses, is most often spread by Varroa mites who carry the disease inside them and infect bee colonies. Infection typically causes deformity and death in bees, especially in the pupae and brood. These colony losses devastate beekeeping industries and pose a major risk to agriculture and the global food supply. While there are medicines for other bee diseases and parasites, there is currently no treatment available to help beekeepers reduce viruses in their colonies. Nearly all colonies have DWV and can often be infected with multiple viruses at any given time. Effective antiviral treatments could help to improve colony health and survival as well as crop pollination efficiency. "We found that engineered algae diets suppressed DWV infection and improved survival in honey bees," said Vincent Ricigliano, research scientist at the ARS Honey Bee Laboratory in Baton Rouge, Louisiana. "When mixed into bee food, the engineered algae boost the bee’s immune system to fight off the targeted virus." Bees feeding on a microalgae pattyHoney bees feed on a pollen patty containing microalgae. (Photo by Vincent Ricigliano, ARS) According to Ricigliano, blue-green algae is the "bee’s knees" of bee food additives. Ricigliano and other ARS researchers previously studied blue-green microscopic algae, also known as microalgae, as a potential food source for honey bees. The algae showed promise since it has a nutritional profile that resembles pollen and is scalable to the level of commercial beekeeping. "In addition to the nutritional benefits and immune-boosting effects, engineered algae strains have the potential to protect bees against a wide variety of pathogens," said Ricigliano. Blue-green algae grow via photosynthesis and can remove carbon dioxide from the atmosphere, making it an ecologically friendly approach to improve the health of honey bees. "This technology represents a potential new class of treatments for honey bees that is highly sustainable and scalable," said Ricigliano. "It can be added directly to supplemental feed without additional processing and easily integrated into beekeepers’ existing management practices. However, there are regulatory considerations that must be addressed before these applications can be fully realized." The researchers filed a patent application for the technology and plan to use variations of it to target additional bee viruses and other pathogens in future studies. *The Agricultural Research Service is the U.S. Department of Agriculture's chief scientific in-house research agency. Daily, ARS focuses on solutions to agricultural problems affecting America. Each dollar invested in U.S. agricultural research results in $20 of economic impact.*


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