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Read the magazine story to find out more.ARS microbiologists Brad Bearson, left, and Shawn Bearson developed a new vaccine that protects against different types of *Salmonella* in turkeys and pigs. Click the image for more information about it. *Salmonella* Vaccine Reduces Animal Disease and Foodborne Illness August 30, 2017 Some types of *Salmonella* cause disease in food animals, like pigs. Others cause foodborne illness in humans. A new vaccine developed by Agricultural Research Service (ARS) scientists in Ames, Iowa, protects against these types of *Salmonella* in food animals. Most *Salmonella* vaccines only protect against one type of the pathogen. This leaves pigs susceptible to disease from other *Salmonella* pathogens. While some *Salmonella* vaccines reduce disease in pigs, they may not protect against *Salmonella* that causes foodborne illness in humans. Microbiologists Shawn Bearson and Brad Bearson, at ARS's Food Safety and Enteric Pathogens Research Unit and ARS's Agroecosystems Management Research Unit, respectively, developed a new vaccine that protects food animals against both human and animal disease-causing *Salmonella*. In experiments, the vaccine protected pigs against two types of *Salmonella*—*Typhimurium* and *Choleraesuis*. It also protected turkeys against *Typhimurium* and a multidrug-resistant *Salmonella* type, Heidelberg—the bacterium responsible for a 2011 outbreak in ground turkey. *Choleraesuis*, the source of major U.S. and global outbreaks in swine in the 1980s and 1990s, causes a severe disease that can kill animals. According to ARS scientists, if an outbreak occurs in the United States, the new vaccine could provide protection against *Choleraesuis*, along with other foodborne *Salmonella* such as *Typhimurium*. The vaccine is also a DIVA—Differentiation of Infected from Vaccinated Animals—meaning it shouldn't interfere with specific tests used to detect natural *Salmonella* infections in pigs. Thus, a producer can differentiate vaccinated animals from those naturally exposed to *Salmonella*. The scientists believe that the vaccine will protect against other types of *Salmonella* in addition to the three strains tested. ARS has filed a patent application for this vaccine technology. Read more about this research in the August 2017 issue of *AgResearch* magazine. For more information contact Sandra Avant, ARS Office of Communications. *The Agricultural Research Service is the U.S. Department of Agriculture's chief scientific in-house research agency. Daily, ARS focuses on solutions to agricultural problems affecting America. Each dollar invested in agricultural research results in $20 of economic impact.*


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