Exhibit 10.8(e)


 


FOURTH AMENDMENT TO


THE AGREEMENT FOR SERVICES RELATED TO KALBITOR®


BY AND BETWEEN


DYAX CORP.


AND


WALGREENS INFUSION SERVICES, INC.


 


THIS FOURTH AMENDMENT
TO THE AGREEMENT FOR SERVICES RELATED TO KALBITOR® (the “Fourth Amendment”) is made and entered
into as of the 30th day of December 2014 (the “Fourth Amendment Effective Date”), by and between DYAX CORP.,
a Delaware corporation (“Dyax”), and WALGREENS INFUSION SERVICES, INC., a Delaware corporation (“Walgreens”),
to amend that certain Agreement For Services Related to Kalbitor, effective as of September 1, 2011, entered into by and between
Dyax and Walgreens, as modified by that certain First Amendment dated as of August 31, 2012, that certain Second Amendment dated
as of September 30, 2013, and that certain Third Amendment dated as of July 1,2014 (collectively, the “Agreement”).
Capitalized terms used herein which are not defined shall have the meanings given to them in the Agreement.


 


RECITALS:


 


WHEREAS, pursuant
to the Agreement, Walgreens provides services related to the home administration of the pharmaceutical product known as Kalbitor;
and,


 


WHEREAS, the parties
desire to modify certain services and associated fees provided by Walgreens, in accordance with the terms and conditions set forth
herein;


 


NOW, THEREFORE, for
and in consideration of the mutual covenants and promises set forth herein and in the Agreement, and other good and valuable consideration,
the receipt and sufficiency of which are hereby acknowledged, Walgreens and Dyax hereby agree to amend the Agreement as follows:


 


AGREEMENT:


 


		1.	The Agreement is hereby amended by adding the following term to Section 2 (DEFINITIONS, CONSTRUCTION):



 


““Service Provider Generated
Patient Referral” shall mean a referral, appropriate form or other written notification setting forth a Patient’s
desire to obtain infusion services that has been principally generated through the efforts of the Service Provider, with any Referral
routed through Service Provider or that includes a notation thereon that refers to Service Provider to be considered a Referral
principally generated through the efforts of Service Provider. References made to “Patient Referral” throughout this
Agreement shall also include “Service Provider Generated Referral.””


 




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		2.	Section 3.7 (a) (First Right to Provide Services) is hereby deleted in its entirety and replaced
with the following:



 


“Dyax agrees that Service Provider
shall be provided with the first right to provide Services in respect of any Patient that is the subject of a Service Provider
Generated Patient Referral. Further, Dyax agrees that all other referrals shall be allocated in a manner that treats Service Provider
no less favorably than any other in-network pharmacy or provider of infusion services.”


 


		3.	The following is hereby added to the Agreement as a new Section 5.6:



 


“5.6      Data Utilization.
Notwithstanding anything to the contrary set forth in the Agreement, all data collected by Service Provider in the performance
of the Data Services: (i) is and shall remain the property of Service Provider; (ii) constitutes the Confidential Information of
Service Provider pursuant to Section 2 and Section 12 of this Agreement, subject to the use and disclosure rights expressly granted
to Dyax in the Agreement (it being the intention of the Parties to not alter or diminish such rights by the terms of this Section
5.6); and (iii) may be used and disclosed by Service Provider in any manner and for any purpose permitted under Applicable Law.”


 


		4.	The Agreement is hereby amended by deleting the first two sentences of Section B(1) of Schedule
A (Description of Services).



 


		5.	The Agreement is hereby amended by adding the following new paragraph to Section B “Initial
Intake” of Schedule A (Description of Services):



 


“Service Provider will forward
Service Provider Generated Patient Referral to Kalbitor Access, which is the centralized customer support center operated or engaged
by Dyax provided the Service Provider has a signed HIPAA Patient Authorization Form on file. If no HIPAA Authorization Form is
on file, Service Provider will, in accordance with Service Provider’s standard operating procedures, advise the Patient of
any relevant patient services available through Kalbitor Access. Service Provider shall, promptly following its receipt of a Service
Provider Generated Patient Referral, obtain from the Patient’s physician a treatment order sheet confirming the physician’s
orders for Infusion Services and the dispensing of an anaphylaxis kit.”


 


		6.	The parties hereby ratify the terms and conditions of the Agreement, as amended herein.



 


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IN WITNESS WHEREOF,
Walgreens and Dyax, through their respective duly authorized and acting representatives, have executed and delivered this Fourth
Amendment to be effective as of the Fourth Amendment Effective Date.


 


	DYAX CORP.	 	WALGREEN INFUSION SERVICES, INC.
	 	 	 
	By: /s/Kathleen DiRamio	 	By: /s/Lori Zsitek
	 	 	 
	Name: Kathleen DiRamio	 	Name: Lori Zsitek
	 	 	 
	Title: Associate Director, Nursing Services	 	Title: VP, Operations


 




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