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          Guidance for Industry: Policy Regarding N-acetyl-L-cysteineSearch for FDA Guidance Documents GUIDANCE DOCUMENT
	Guidance for Industry: Policy Regarding N-acetyl-L-cysteine
					
		
		August 2022


	Download the  Final Guidance Document
	    
      	      		Read the Federal Register Notice 

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    PrintDocket Number:
		    FDA-2022-D-0490
	    	    		    Issued by:
		    Guidance Issuing Office
          Center for Food Safety and Applied Nutrition


The purpose of this guidance is to advise dietary supplement manufacturers, distributors, and other stakeholders of our intent to exercise enforcement discretion with respect to the sale and distribution of certain products that contain N-acetyl-L-cysteine (NAC) and are labeled as dietary supplements. As described below, the enforcement discretion policy applies to products that would be lawfully marketed dietary supplements if NAC were not excluded from the definition of “dietary supplement” and that are not otherwise in violation of the Federal Food, Drug, and Cosmetic Act (FD&C Act).

The contents of this document do not have the force and effect of law and are not meant to bind the public in any way, unless specifically incorporated into a contract. This document is intended only to provide clarity to the public regarding existing requirements under the law. FDA guidance documents, including this guidance, should be viewed only as recommendations, unless specific regulatory or statutory requirements are cited. The use of the word should in FDA guidances means that something is suggested or recommended, but not required.

Download the Guidance

Related Resources

Dietary Supplements Guidance Documents & Regulatory Information
	Information for Industry on Dietary Supplements
	FDA Issues Response to Two Citizen Petitions on NAC in Dietary Supplements (March 2022)


 
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						All written comments should be identified with this document's docket number: FDA-2022-D-0490.

                                                                                  Content current as of:
      08/01/2022
         
                  
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