[Federal Register Volume 60, Number 104 (Wednesday, May 31, 1995)]
[Notices]
[Page 28423]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 95-13284]



-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES
Public Health Service


National Toxicology Program; Board of Scientific Counselors' 
Meeting

    Pursuant to Public Law 92-463, notice is hereby given of a meeting 
of the National Toxicology Program (NTP) Board of Scientific 
Counselors, U. S. Public Health Service, in the Conference Center, 
Building 101, South Campus, National Institute of Environmental Health 
Sciences (NIEHS), 111 Alexander Drive, Research Triangle Park, North 
Carolina, on June 29, 1995.
    The primary agenda topic will be concerned with the report and 
recommendations of the ad hoc working group of the NTP Board from their 
review of the criteria for listing substances in the Biennial Report on 
Carcinogens (BRC) (formerly Annual Report on Carcinogens) on April 24 
and 25, 1995. Specifically, the Board will:
    (1) review the report and recommendations of the ad hoc working 
group;
    (2) receive public comments on the report; and
    (3) develop Board recommendations concerning the selection 
criteria.
    The preliminary agenda topics with approximate times are as 
follows:

8:30 a.m.-8:45 a.m.--Report of the Director, NTP.
8:45 a.m.-9:15 a.m.--Report of the Director, Environmental Toxicology 
Program (ETP).
9:15 a.m.-9:45 a.m.--Report of the NTP Workshop on ``Mechanism-Based 
Toxicology in Cancer Risk Assessment: Implications for Research, 
Regulation, and Legislation,'' held January 11-13, 1995.
10:00 a.m.-10:20 a.m.--Report on the Meeting of the Ad Hoc Working 
Group to Review Criteria for Listing of Substances in the BRC.
10:20 a.m.-11:00 a.m.--Board Discussion of the Working Group Report.
11:00 a.m.-12:00 p.m.--Public Comments on the Report.
1:15 p.m.-2:15 p.m.--Further Discussion and Development of 
Recommendations by the Board Concerning the BRC Selection Criteria.
2:15 p.m.-2:25 p.m.--Report on Technical Reports Review Subcommittee 
Activities.
2:25 p.m.-2:55 p.m.--Chemicals Nominated and Recommended for Study by 
the Interagency Committee for Chemical Evaluation and Coordination 
(ICCEC) on December 14, 1994, will be presented for discussion and time 
will be allowed for public comment. Chemicals evaluated by the ICCEC 
were (with CAS Nos. in parentheses): (1) Arsenic Trioxide (1327-53-3); 
(2) Ethidium Bromide (1239-45-8); (3) 5-(Hydroxymethyl)furfural (67-47-
0); (4) Isoamyl Acetate (123-92-2); and (5) MX [3-chloro-4-
(dichloromethyl) 5-hydroxy-2-(5H)-furanone] (77439-76-0). One chemical 
previously evaluated was re-reviewed: Hexamethyldisilazane (999-97-3).
3:15 p.m.-3:45 p.m.--Concept Review:
    In Vitro and In Vivo Genetic Toxicology Testing.
3:45 p.m.-4:30 p.m.--Alternative Methods--Status and Plans:

--RFA for Research in ``Mechanistically Based Alternative Methods in 
Toxicology.''
--Proposed Workshop on ``Alternative Test Methods in Toxicology: 
Validation and Regulatory Acceptance.''
Adjournment

Public Comments Encouraged

    The meeting is open to the public, and public input concerning the 
criteria for listing a substance in the Biennial Report on Carcinogens 
is encouraged. A brief summary of the ad hoc working group meeting, 
including the current and proposed revised criteria, is available on 
request from the NTP Liaison Office, P.O. Box 12233, MD B3-01, Research 
Triangle Park, NC 27709, phone: (919) 541-0530, FAX: (919) 541-0295. 
This summary also will be published in the Federal Register in late May 
or early June. Written comments can be submitted to Dr. Larry G. Hart, 
Executive Secretary. Formal oral comments during the meeting will be 
limited to five minutes to permit maximum participation. Written 
comments accompanying oral statements are encouraged. To assure 
consideration by the Board at the meeting, written comments must be 
received by June 23, 1995. Registration to attend is not required; 
however, to ensure adequate seating, we ask that those planning to 
attend let us know. To register, submit written comments or announce 
intention to make oral comments, receive information on the agenda, or 
be put on the mailing list for summary minutes subsequent to the 
meeting, please contact: Dr. L. G. Hart, P.O. Box 12233, Research 
Triangle Park, NC 27709; telephone: (919) 541-3971; FAX: (919) 541-
0719.

    Dated: May 18, 1995.
Kenneth Olden,
Director, National Toxicology Program.
[FR Doc. 95-13284 Filed 5-30-95; 8:45 am]
BILLING CODE 4140-01-P