Exhibit 99.1

REGISTRATION RIGHTS AGREEMENT

THIS
REGISTRATION RIGHTS AGREEMENT (the Registration Rights Agreement) is
dated as of February 25, 2010, and is entered into by and between MAKO Surgical
Corp., a Delaware corporation having its principal office at 2555 Davie Road,
Fort Lauderdale, Florida 33317 (the Company), and Z-Kat, Inc., a
Florida corporation having its principal office at 5011 South State Road 7,
Suite 106, Davie, Florida 33314 (the Holder).

W
I T N E S S E T H:

WHEREAS,
pursuant to the Asset Purchase Agreement, dated as of January 8, 2010 (the Purchase
Agreement), by and between the Company and the Holder, the Company is
issuing shares of the Companys common stock, $0.001 par value per share (the MAKO
Common Stock), to the Holder in consideration for certain of the Holders
intellectual property assets.

WHEREAS,
the execution of this Registration Rights Agreement is a condition to the
closing of the transactions contemplated by the Purchase Agreement.

WHEREAS,
pursuant to the terms and conditions set forth in this Registration Rights
Agreement, the Company and the Holder desire to allow the Holder to sell
publicly the shares of MAKO Common Stock acquired or to be acquired by the
Holder pursuant to the Purchase Agreement (the shares of MAKO Common Stock
issued to the Holder pursuant to the terms of the Purchase Agreement are
hereinafter referred to as the Registrable Shares) pursuant to a
registration statement filed by the Company under the Securities Act of 1933,
as amended (Act).

NOW,
THEREFORE, in consideration of the mutual covenants and promises herein made
and mutual benefits to be derived from this Registration Rights Agreement, it
is hereby agreed as follows:

1.       Piggyback
Registration.

(a) During
the period commencing on the date of this Registration Rights Agreement and
ending on February 24, 2011, if the Company at any time proposes to file a
Registration Statement with the Securities and Exchange Commission (the Commission)
under the Act with respect to any offering of the MAKO Common Stock for its own
account or for the account of any holders (other than (i) a registration of
MAKO Common Stock solely relating to an offering and sale to employees or directors
of the Company pursuant to any employee stock plan or other employee benefit
plan arrangement, including any Registration on Form S-8 (or any successor form
thereto) or (ii) a registration of MAKO Common Stock issued solely in an

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exchange offer, acquisition or business combination including any
registration on Form S-4 (or any successor form thereto)), then, as soon as
practicable (but in no event less than fifteen (15) days prior to the proposed
date of the initial filing of such Registration Statement), the Company shall
give written notice of such proposed filing to the Holder and such notice shall
(i) specify the kind and number of securities proposed to be registered and the
proposed offering price or prices and distribution arrangements, but only to
the extent that such information is reasonably available to the Company at the
time that such notice is delivered; (ii) include such other information, if
any, that at the time and under the circumstances would be appropriate to
include in such notice; and (iii) offer the Holder the opportunity to register
such number of Registrable Securities as the Holder may request in writing (a Piggyback
Registration). Subject to Section 1(b), the Company shall
include in such Registration Statement all Registrable Securities requested
within two (2) business days after the receipt by the Holder of any such notice
(which request shall specify the aggregate amount of Registrable Securities
intended to be disposed of by the Holder) to be included in the Registration
Statement for such offering pursuant to a Piggyback Registration; provided,
however, that if at any time after giving written notice of its
intention to register any MAKO Common Stock and prior to the effective date of
the Registration Statement filed in connection with such Piggyback
Registration, the Company shall determine for any or no reason not to register
or to delay registration of any such MAKO Common Stock, then the Company may,
at its election, give written notice of such determination to the Holder and,
thereupon (x) in the case of a determination not to register, shall be relieved
of its obligation to register any Registrable Securities in connection with
such registration and (y) in the case of a determination to delay registering,
shall be permitted to delay registering any Registrable Securities for the same
period as the delay in registering such other securities that were to be
registered in such Piggyback Registration. If the offering pursuant to such
Registration Statement is to be underwritten, the Holder must participate in
such underwritten offering and be subject to the terms and conditions thereof.
If the offering pursuant to such Registration Statement is to be on any other
basis, then the Holder must participate in such offering on such basis and be
subject to the terms and conditions thereof. The Holder shall be permitted to
withdraw all or part of the Registrable Securities from a Piggyback
Registration at any time prior to the effective date thereof.

(b) If
the managing underwriter (or underwriters) of any proposed underwritten
offering in a Piggyback Registration informs the Company and the Holder in
writing that the total amount of securities which the Holder and any other
persons intend to include in such offering exceeds the number which can be sold
in such offering without being likely to have a significant adverse effect on
the price, timing or distribution of the securities offered in such offering or
the market for the MAKO Common Stock, then the securities to be included in
such registration shall be (i) first, 100% of the securities that the Company
proposes to sell, and (ii) second, and only if all the securities referenced in
clause (i) of this Section 1(b), have been included, the number
of Registrable Securities that, in the opinion of such underwriter or
underwriters, can be sold without having such adverse effect based on the
securities requested to be included and (iii) third, and only if all of the
Registrable Securities referenced in clauses (i) and (ii) have
been included, any other securities eligible for inclusion in such
registration.

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(c) The
Company shall only be required to include the Holders Registrable Securities
in one Piggyback Registration; provided, however, that a
Piggyback Registration filed by the Company pursuant to this Section 1
shall not count as the one allowed Piggyback Registration unless all of the
Holders Registrable Securities requested to be included in such Piggyback Registration
are so registered and the Piggyback Registration has become effective under the
Act.

2.       Demand
Registration.

(a)
If as of February 25, 2011,the Holder has determined that it is
unable at that time to sell the Registrable Securities free from any of the
volume restrictions imposed by Rule 144 under the Act (or any successor rule
thereto) and such determination is set forth in a written opinion of Holders
legal counsel addressed to the Company, then beginning on such date the Holder
may make a written request of the Company (Demand Registration Request)
to file a registration statement (the Demand Registration Statement)
with the Commission under the Act covering the proposed sale to the public of
the specified number of such Registrable Shares on Form S-3 (or any successor
form thereto) or any other registration statement form that is available for
use by the Company. The Demand Registration Request must be dated, accompanied
by the written opinion of Holders counsel discussed above, contain a request
as to the exact number of Registrable Securities the Holder wishes to register
pursuant to a Demand Registration Statement, and be signed by an authorized
officer of the Holder. In connection with the filing of the Demand Registration
Statement, the Company shall also use commercially reasonable efforts to
register or qualify such Registrable Shares covered by such Registration
Statement under such U.S. state securities or blue sky laws as the Holder shall
reasonably request; provided, however, that, with respect to the
foregoing, the Company shall not for any such purpose be required to qualify
generally to do business as a foreign corporation in any jurisdiction where,
but for the requirements of this Section 2(a) it would not be obligated
to be so qualified, to subject itself to taxation in any such jurisdiction, or
to consent to general service of process in any such jurisdiction. Any offering
and sale of Registrable Shares hereunder shall be effected through normal
brokers transactions on The Nasdaq Global Market or on any securities exchange
or market on which the MAKO Common Stock is then listed or traded or in
privately negotiated transactions.

(b)
Subject to Section 3 hereof, upon receipt of a Demand Registration
Request in compliance with Section 2(a) from the Holder and subject to
the other provisions of Section 2(a), the Company will, as promptly as
practicable and in any event within 45 days after receipt of the Demand Registration
Request prepare and file with the Commission a registration statement on Form
S-3 (or any successor form thereto) or any other registration statement form
that is available for use by the Company covering such proposed sale of all
Registrable Shares requested to be registered pursuant to the Demand
Registration Request.

(c)
Subject to Section 3 hereof, the Company will use commercially
reasonable efforts to have the Registration Statement declared effective under
the Act by the Commission (and under applicable U.S. state securities laws by
all applicable U.S. state

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securities authorities) as soon as practicable after the filing thereof
and to maintain the effectiveness thereof for a period of not longer than 120
days (or until all Registrable Shares covered thereby have been sold, if such
sales are completed before the end of such 120-day period).

(d) The
Company shall only be required to file one Demand Registration Statement for
the benefit of the Holder hereunder; provided, however, that a
Demand Registration Statement filed by the Company pursuant to this Section 2
shall not count as the one allowed Demand Registration Statement until it has
become effective under the Act and been maintained effective for the period
specified in Section 2(c) hereof. The Company shall not be required
to file a Demand Registration Statement until such time as any Piggyback
Registration relating to the Registrable Securities is no longer effective.
Notwithstanding the foregoing, the Company shall have no obligation to file a
Demand Registration Statement or to obtain effectiveness of the Demand
Registration Statement, or to maintain the effectiveness of the Demand
Registration Statement, beginning on the first date on which the holding period
for the Registrable Securities set forth in Rule 144 under the Act (or any
successor rule thereto) has been satisfied such that the Holder can sell the
Registrable Securities free from any of the volume restrictions imposed by Rule
144 under the Act. The Companys obligations to file a Demand Registration
Statement for the benefit of the Holder shall end on February 24, 2012.

(e) The
Company shall be entitled to include, as part of the Registration Statement
filed pursuant to the Demand Registration Request, additional shares of MAKO
Common Stock proposed to be sold by other shareholders of the Company or shares
of MAKO Common Stock proposed to be issued by the Company; provided, however,
that the rights of any other shareholders to include MAKO Common Stock under
such Demand Registration Statement shall be subordinate in all respects to the
prior rights of the Holder to include Registrable Shares thereunder if a
conflict of interests thereunder shall occur among such parties.

3.        Denial,
Postponement or Suspension of Registration. If in the good faith judgment
of the Company, following consultation with outside legal counsel, it would be
detrimental to the Company and its shareholders for sales and resales of MAKO
Common Stock to be made pursuant to a Demand Registration Statement or a
Piggyback Registration due to the existence of a material development or
potential material development involving the Company that the Company would be
obligated to disclose in the Demand Registration Statement or the Piggyback
Registration, which disclosure would be premature or otherwise inadvisable at
such time or could have a material adverse effect on the Company, then the
Company may: (a) postpone, for a reasonable period of time not to exceed
90 calendar days (but in any event not to extend beyond the date of public
disclosure of the information, or the date of abandonment or termination of the
potential material developments) (i) the filing of a registration statement
otherwise required to be prepared and filed by it pursuant to Section 2, and
(ii) the effective date with the Commission of the Demand Registration
Statement, and (b) suspend sales by the Company, the Holder or any other person
under any Demand Registration Statement or pursuant to a Piggyback
Registration; provided, however, that in computing the 120-day
period for which the Company is required to maintain effectiveness of the
Demand Registration Statement, the

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period of any such suspension shall not be included. The Company
shall give prompt written notice to the Holder of any such postponement or
suspension and shall likewise give prompt written notice to the Holder of
termination of such postponement or suspension. For a period not to exceed 90
calendar days from such notice, the Holder hereby agrees to postpone the sale
of any Registrable Shares registered pursuant to the Demand Registration
Statement during any postponement or suspension of sales of MAKO Common Stock
thereunder by the Company until it is advised in writing by the Company that
sales of the Registrable Securities may be resumed.

4.          Expenses.
The Holder participating in a Piggyback Registration and/or a Demand
Registration Statement shall pay (a) the expenses of any attorneys, accountants
or other advisors or professionals which it or its officers, directors,
shareholders or control persons engage in connection with the Holders sale of
Registrable Shares pursuant to the Piggyback Registration and/or the Demand
Registration Statement and (b) all brokerage commissions and discounts, if any,
associated with the Registrable Shares being sold by the Holders pursuant to
the Piggyback Registration and/or the Demand Registration Statement. The Company
shall pay all other costs and expenses incurred by it and the Holder associated
with the Piggyback Registration and/or the Demand Registration Statement
(including, without limitation, all legal and accounting fees and expenses,
printing costs and filing fees incurred by the Company).

5.          Further
Cooperation; Confidentiality. In connection with each of the Piggyback
Registration and the Demand Registration Statement, the Holder will furnish or
cause to be furnished such further information with respect thereto, and render
such further cooperation, to the Company, as the Company may request. Upon
receiving any notice from the Company hereunder respecting any contemplated or
pending registration statement of the Company, the Holder shall strictly
maintain the confidentiality of such contemplated or pending registration
statement and shall make no public disclosures or comments with respect
thereto, and shall not otherwise trade in any securities of the Company during
such period.

6.          Indemnification

(a) General.
In connection with any Piggyback Registration or a Demand Registration
Statement that may be filed pursuant to this Registration Rights Agreement, the
Holder shall indemnify and hold harmless the Company and its respective
officers, directors and controlling persons from any and all loss, liability,
claims, damages and expenses (including reasonable attorneys fees and
disbursements and reasonable expenses of investigation) incurred by them insofar
as such losses, liabilities, claims, damages and expenses arise out of or are
based upon any untrue statement or alleged untrue statement of a material fact
contained in the registration statement or prospectus covering the Registrable
Shares to be sold or arise out of or are based upon the omission or alleged
omission to state therein a material fact required to be stated therein or
necessary to make the statements therein (in the case of a prospectus, in light
of the circumstances under which they were made) not misleading; provided,
however, that the Holder shall only be liable in any such case to the
extent that any such loss arises out of or is based upon any such untrue
statement or alleged untrue statement or omission or alleged omission made therein
in reliance upon and in conformity with information relating to such

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Holder as furnished in writing to the Company by or on behalf of the
Holder for use in the registration statement or prospectus covering the
Registrable Shares to be sold. Except to the extent set forth in the foregoing
sentence, the Company shall indemnify and hold harmless the Holder (and, if
applicable, its officers, directors, partners and controlling persons)
participating in the Piggyback Registration and/or Demand Registration
Statement from any and all loss, liability, claims, damages and expenses
(including reasonable attorneys fees and disbursements and reasonable expenses
of investigation) incurred by the Holder insofar as such losses, liabilities,
claims, damages and expenses arise out of or are based upon any untrue
statement or alleged untrue statement of a material fact contained in any
registration statement or preliminary prospectus or definitive prospectus or
any amendment thereof or supplement thereto or any omission or alleged omission
of a material fact required to be stated therein or necessary to make the
statements therein not misleading.

(b) Indemnification
Procedure. Any person entitled to
indemnification hereunder will (a) give prompt written notice to the
indemnifying party of any claim with respect to which it seeks indemnification,
provided that the failure of any indemnified party to give notice shall not
relieve the indemnifying party of its obligations hereunder, except to the
extent the indemnifying party is actually prejudiced by such failure; and (b)
unless in such indemnified partys reasonable judgment a conflict of interest
between such indemnified and indemnifying parties may exist with respect to
such claim, permit such indemnifying party to assume the defense of such claim
with counsel reasonably satisfactory to the indemnified party. If such defense
is assumed, the indemnified party will not be subject to any liability for any
settlement made by the indemnified party without its consent (but such consent
will not be unreasonably withheld). An indemnifying party who is not entitled
to, or elects not to assume the defense of a claim, will not be obligated to
pay the fees and expenses of more than one counsel for all parties indemnified
by such indemnifying party with respect to such claim, unless in the reasonable
judgment of any indemnified party a conflict of interest may exist between such
indemnified party and any other of such indemnified parties with respect to
such claim (it being understood that the indemnifying party shall not be liable
for the expenses of more than one separate counsel in the event of the conflict
of interest situation described in this sentence).

(c) Survival.
The indemnification provided for under this Agreement will remain in full force
and effect regardless of any investigation made by or on behalf of the
indemnified party or any officer, director or controlling person of such
indemnified party and will survive the transfer of securities.

(d) Contribution. If the
indemnification provided for in this Section 6 from the indemnifying party is
unavailable to the indemnified party, then the indemnifying party, instead of
indemnifying the indemnified party, shall contribute to and pay the amount paid
or payable by such indemnified party as a result of the loss, claim, damage,
liability or expenses (collectively, the Claim) giving rise to
indemnification hereunder in such proportion as is appropriate to reflect the
relative fault of the indemnifying and indemnified party in connection with the
actions which gave rise to the Claim. The relative fault of the indemnifying
party and the indemnified party shall be determined by reference to, among
other things, whether the action

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in question has been made by, or relates to,
information supplied by such indemnifying party or indemnified party, and the
parties relative intent, knowledge, access to information and opportunity to
correct or prevent such action. The Company and the Holder agree that it would
not be just and equitable if contribution and payment pursuant to this Section
6(d) were determined by pro-rata allocation or by any other allocation method
which does not take into account the equitable considerations referred to in
the preceding sentence. The amount paid or payable as a result of a Claim shall
include any documented, out-of-pocket legal or other fees and expenses
reasonably incurred by such party in connection with such Claim. However, no
person guilty of fraudulent misrepresentation (within the meaning of Section
11(f) of the Act) shall be entitled to contribution and payment from any person
who was not guilty of such fraudulent misrepresentation.

7.       Additional
Matters.

(a) This
Registration Rights Agreement shall be construed and enforced in accordance
with the internal laws of the State of New York.

(b) All
notices and other communications which are required under this Registration
Rights Agreement or may be given hereunder shall be in writing and shall be
deemed to have been duly given (i) when delivered personally, (ii) if sent by
facsimile, when receipt thereof is acknowledged by a confirmation copy of the
same, (iii) the next business day following the day on which the same has been
delivered prepaid to a nationally recognized overnight courier service, or (iv)
three business days following deposit in the mail as registered or certified,
postage prepaid in each case. All such notices shall be addressed to the
parties at their respective addresses first set forth above.

(c) Along
with the Purchase Agreement and the other agreements and instruments provided
therein, as well as the Non-Disclosure Agreement between the parties dated
December 10, 2009, this instrument embodies the entire agreement between the
parties hereto with respect to the transactions contemplated herein, and
supersedes all prior agreements and understandings between the parties.

(d) This
Registration Rights Agreement may be executed in original or in one or more
counterparts, each of which shall be deemed an original and all of which, when
taken together, shall constitute one and the same instrument, and may be
transmitted by fax or electronic mail.

(e) This
Registration Rights Agreement shall not be assigned by Holder without the
written consent of the Company, which consent will not be unreasonably
withheld. This Agreement shall be binding upon and inure to the benefit of the
respective parties hereto, any successor and assign of the Company and, if the
consent required by this Section 7(e) is properly secured, the
successors and permitted assigns of such party. Upon any assignment hereunder,
each assignee of the Holder shall become the Holder for all purposes under
this Registration Rights Agreement. Any assignment in violation of this Section
7(e) shall be null and void for all purposes and the party attempting to
effect such an assignment shall be jointly and severally

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liable for any claims against or incurred by the nonassigning parties
as a result of such attempted assignment.

(f) In
the event that any part of this Registration Rights Agreement shall be held to
be invalid or unenforceable, the remaining parts thereof shall nevertheless
continue to be valid and enforceable as though the invalid portions were not a
part hereof.

(g) The
headings used in this Registration Rights Agreement are for convenience only
and shall not constitute a part of this Agreement.

(h) Failure
by any party at any time to require performance under this Agreement by the
other party, or to claim a breach of any provision of this Agreement, shall not
be construed as a waiver of any right accruing under this Agreement, nor shall
it affect any subsequent breach of this Agreement or the effectiveness of any
provision of this Agreement, or prejudice any party as regards to any
subsequent action. A waiver of any right accruing to any party pursuant to this
Agreement shall not be effective unless given in writing.

IN
WITNESS WHEREOF, the parties hereto have caused this Registration Rights
Agreement to be duly executed all as of the day and year first above written.

| |                                                             |                       | 
| | ----------------------------------------------------------- | --------------------- | 
| | MAKO
 SURGICAL CORP.                                       
| |                                                             |                      
| | By:                                                         | /s/ Fritz L.
 LaPorte | 
| | Name: Fritz
 L. LaPorte                                    
| | Title:
 Senior Vice President of Finance and Administration
| |                                                             |                      
| | Z-KAT, INC.                                                
| |                                                             |                      
| | By:                                                         | /s/ John R.
 Whitman 
| | Name: John
 R. Whitman                                     
| | Title: Chairman                                            

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