| Delaware                                                     |   | 20-5894890                         |
|--------------------------------------------------------------|--------|------------------------------------|
| (State or OtherJurisdiction ofIncorporation or Organization) |   | (I.R.S.EmployerIdentification No.) |

| 400 Connell Drive,Suite 5000, Berkeley Heights, NJ |   | 07922     |
|----------------------------------------------------|--------|-----------|
| (Address ofPrincipal Executive Offices)            |   | (ZipCode) |

| Title of eachclass            |   | Name of eachexchange on which registered |
|-------------------------------|--------|------------------------------------------|
| Common Stock,$0.001 Par Value |   | NYSE AmericanLLC                         |

| Large acceleratedfiler ☐ | Accelerated filer☐         |
|---------------------------------|-----------------------------------|
|                            |                              |
| Non-acceleratedfiler ☐   | Smaller reportingcompany ☒ |

| Item15. | Exhibits andFinancial Schedules |  2 |
|---------|---------------------------------|---------|

| ExhibitNumber |   |  Description ofDocument                                                                                                                                                                     |   | Registrant’sForm |   |  Dated |   | ExhibitNumber |   | FiledHerewith |
|---------------|--------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|-------------------------|--------|-------------|--------|---------------|--------|---------------|
| 1.1           |   | At-the-MarketIssuance Sales Agreement, dated April 8, 2015, between CorMedixInc. and MLV.                                                                                                        |   | S-3                     |   | 4/09/2015   |   | 1.2           |   |          |
| 1.2           |   | AmendmentNo. 1, dated December 8, 2017, to At-the-Market Issuance SalesAgreement, dated April 8, 2015, between CorMedix Inc. and B. RileyFBR, Inc.                                               |   | 8-K                     |   | 12/08/2017  |   | 1.1           |   |          |
| 1.3           |   | UnderwritingAgreement, dated April 28, 2017 by and among CorMedix Inc. and H.C.Wainwright & Co., LLC.                                                                                        |   | 8-K                     |   | 5/03/2017   |   | 1.1           |   |          |
| 1.4           |   | AtMarket Issuance Sales Agreement, dated March 9, 2018, betweenCorMedix Inc. and B. Riley FBR, Inc.                                                                                              |   | S-3                     |   | 3/09/2018   |   | 1.1           |   |          |
| 3.1           |   | Form of Amended andRestated Certificate of Incorporation.                                                                                                                                        |   | S-1/A                   |   | 3/01/2010   |   | 3.3           |   |          |
| 3.2           |   | Certificate ofAmendment to Amended and Restated Certificate of Incorporation,dated February 24, 2010.                                                                                            |   | S-1/A                   |   | 3/19/2010   |   | 3.5           |   |          |
| 3.3           |   | Form of Amended andRestated Bylaws as amended April 19, 2016.                                                                                                                                    |   | 10-Q                    |   | 5/10/2016   |   | 3.1           |   |          |
| 3.4           |   | Certificate ofAmendment to Amended and Restated Certificate of Incorporation,dated December 3, 2012.                                                                                             |   | 10-K                    |   | 3/27/2013   |   | 3.3           |   |          |
| 3.5           |   | Certificate ofAmendment to Amended and Restated Certificate of Incorporation,dated August 9, 2017.                                                                                               |   | 8-K                     |   | 8/10/2017   |   | 3.1           |   |          |
| 3.6           |   | Certificate ofDesignation of Series A Non-Voting Convertible Preferred Stock ofCorMedix Inc., filed with the Delaware Secretary of State onFebruary 18, 2013, as corrected on February 19, 2013. |   | 8-K                     |   | 2/19/2013   |   | 3.3           |   |          |
| 3.7           |   | Certificate ofDesignation of Series B Non-Voting Convertible Preferred Stock ofCorMedix Inc., filed with the Delaware Secretary of State on July26, 2013.                                        |   | 8-K                     |   | 7/26/2013   |   | 3.4           |   |          |
| 3.8           |   | Certificate ofDesignation of Series C-1 Non-Voting Convertible Preferred Stock ofCorMedix Inc., filed with the Delaware Secretary of State onOctober 21, 2013.                                   |   | 8-K                     |   | 10/23/2013  |   | 3.5           |   |          |
| 3.9           |   | Amended andRestated Certificate of Designation of Series C-2 Non-VotingConvertible Preferred Stock of CorMedix Inc., filed with theDelaware Secretary of State on September 15, 2014.            |   | 8-K                     |   | 9/16/2014   |   | 3.15          |   |          |
| 3.10          |   | Amended andRestated Certificate of Designation of Series C-3 Non-VotingConvertible Preferred Stock of CorMedix Inc., filed with theDelaware Secretary of State on September 15, 2014.            |   | 8-K                     |   | 9/16/2014   |   | 3.16          |   |          |
| 3.11          |   | Amended andRestated Certificate of Designation of Series D Non-VotingConvertible Preferred Stock of CorMedix Inc., filed with theDelaware Secretary of State on September 15, 2014.              |   | 8-K                     |   | 9/16/2014   |   | 3.17          |   |          |

| ExhibitNumber  |   | Description ofDocument                                                                                                                                                              |   | Registrant’sForm |   | Dated      |   | ExhibitNumber |   |  FiledHerewith |
|---------------------|--------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|-------------------------|--------|------------|--------|---------------|--------|---------------------|
| 3.12                |   | Amended andRestated Certificate of Designation of Series E Non-VotingConvertible Preferred Stock of CorMedix Inc., filed with theDelaware Secretary of State on September 15, 2014. |   | 8-K                     |   | 9/16/2014  |   | 3.18          |   |                |
| 3.13                |   | Amended andRestated Certificate of Designation of Series F Non-VotingConvertible Preferred Stock of CorMedix Inc., filed with theDelaware Secretary of State on December 11, 2017.  |   | 8-K                     |   | 12/11/2017 |   | 3.1           |   |                |
| 4.1                 |   | Specimen of CommonStock Certificate.                                                                                                                                                |   | S-1/A                   |   | 3/19/2010  |   | 4.1           |   |                |
| 4.2                 |   | Form of Warrantissued on February 19, 2013.                                                                                                                                         |   | 8-K                     |   | 2/19/2013  |   | 4.13          |   |                |
| 4.3                 |   | Form of Warrantissued to ND Partners on April 11, 2013.                                                                                                                             |   | 10-Q                    |   | 5/15/2013  |   | 4.18          |   |                |
| 4.4                 |   | Form of Warrantissued on July 30, 2013.                                                                                                                                             |   | 8-K                     |   | 7/26/2013  |   | 4.21          |   |                |
| 4.5                 |   | Form of Warrantissued on October 22, 2013.                                                                                                                                          |   | 8-K                     |   | 10/18/2013 |   | 4.22          |   |                |
| 4.6                 |   | Form of Warrantissued on January 8, 2014.                                                                                                                                           |   | 8-K                     |   | 1/09/2014  |   | 4.23          |   |                |
| 4.7                 |   | Form of Warrantissued on March 10, 2014                                                                                                                                             |   | 8-K                     |   | 03/05/2014 |   | 4.24          |   |                |
| 4.8                 |   | Warrant issuedMarch 3, 2015.                                                                                                                                                        |   | 8-K                     |   | 03/04/2015 |   | 4.1           |   |                |
| 4.9                 |   | Amended andRestated Warrant originally issued March 24, 2010.                                                                                                                       |   | 8-K                     |   | 03/04/2015 |   | 4.3           |   |                |
| 4.10                |   | Amended andRestated Warrant originally issued May 30, 2013.                                                                                                                         |   | 8-K                     |   | 03/04/2015 |   | 4.2           |   |                |
| 4.11                |   | Registration RightsAgreement, dated March 3, 2015, by and between CorMedix Inc. andManchester Securities Corp.                                                                      |   | 8-K                     |   | 03/04/2015 |   | 4.5           |   |                |
| 4.12                |   | Formof Series A Warrant to Purchase Common Stock of CorMedix Inc.issued on May 3, 2017.                                                                                             |   | 8-K                     |   | 5/03/2017  |   | 4.1           |   |                |
| 4.13                |   | Formof Series B Warrant to Purchase Common Stock of CorMedix Inc.issued on May 3, 2017.                                                                                             |   | 8-K                     |   | 5/03/2017  |   | 4.2           |   |                |
| 4.14                |   | Formof Underwriter’s Warrant to Purchase Common Stock of CorMedixInc., issued May 3, 2017.                                                                                   |   | 8-K                     |   | 5/03/2017  |   | 4.3           |   |                |
| 4.15                |   | Formof Warrant issued on November 16, 2017.                                                                                                                                         |   | 8-K                     |   | 11/13/2017 |   | 4.15          |   |                |
| 10.1*               |   | License andAssignment Agreement, dated as of January 30, 2008, between theCompany and ND Partners LLC.                                                                              |   | S-1/A                   |   | 12/31/2009 |   | 10.5          |   |                |
| 10.2                |   | Escrow Agreement,dated as of January 30, 2008, among the Company, ND Partners LLCand the Secretary of the Company, as Escrow Agent.                                                 |   | S-1                     |   | 11/25/2009 |   | 10.6          |   |                |
| 10.3                |   | ConsultingAgreement, dated as of January 30, 2008, between the Company andFrank Prosl.                                                                                              |   | S-1                     |   | 11/25/2009 |   | 10.12         |   |                |
| 10.4                |   | Amended andRestated 2006 Stock Incentive Plan.                                                                                                                                      |   | S-1/A                   |   | 3/01/2010  |   | 10.8          |   |                |
| 10.5                |   | Form ofIndemnification Agreement between the Company and each of itsdirectors and executive officers.                                                                               |   | S-1/A                   |   | 3/01/2010  |   | 10.17         |   |                |
| 10.6                |   | Agreement for Workon Pharmaceutical Advertising dated January 10, 2013 by and betweenMKM Co-Pharma GmbH and CorMedix Inc.                                                           |   | 8-K                     |   | 1/16/2013  |   | 10.22         |   |                |

| ExhibitNumber |   | Description ofDocument                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            |   | Registrant’sForm |   | Dated      |   |   ExhibitNumber |   |  FiledHerewith |
|---------------|--------|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|-------------------------|--------|------------|--------|----------------------|--------|---------------------|
| 10.7          |   | 2013 StockIncentive Plan                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          |   | 10-K                    |   | 3/27/2013  |   | 10.27                |   |                |
| 10.8          |   | Form of SecuritiesPurchase Agreement, dated January 7, 2014, between CorMedix Inc.and the investors named therein.                                                                                                                                                                                                                                                                                                                                                                                                |   | 8-K                     |   | 1/09/2014  |   | 10.36                |   |                |
| 10.9          |   | PreliminaryServices Agreement dated April 8, 2015, between CorMedix Inc. and[RC]2 Pharma Connect LLC.                                                                                                                                                                                                                                                                                                                                                                                                             |   | 10-Q                    |   | 8/06/2015  |   | 10.1                 |   |                |
| 10.10         |   | Release of Claimsand Severance Modification, dated July 17, 2015, between RandyMilby and CorMedix Inc.                                                                                                                                                                                                                                                                                                                                                                                                            |   | 10-K                    |   | 3/15/2016  |   | 10.16                |   |                |
| 10.11*        |   | EmploymentAgreement, dated as of September 27, 2016 and effective as ofOctober 3, 2016, between CorMedix, Inc. and KhosoBaluch                                                                                                                                                                                                                                                                                                                                                                                    |   | 8-K                     |   | 10/03/2016 |   | 10.1                 |   |                |
| 10.12*        |   | EmploymentAgreement, effective February 1, 2017, between CorMedix Inc. andRobert Cook.                                                                                                                                                                                                                                                                                                                                                                                                                            |   | 10-K                    |   | 3/16/2017  |   | 10.12                |   |                |
| 10.13*        |   | EmploymentAgreement, effective February 1, 2017, between CorMedix Inc. andJudith Abrams.                                                                                                                                                                                                                                                                                                                                                                                                                          |   | 10-K                    |   | 3/16/2017  |   | 10.13                |   |                |
| 10.14         |   | EmploymentAgreement, effective March 1, 2017, between CorMedix Inc. and JohnArmstrong.                                                                                                                                                                                                                                                                                                                                                                                                                            |   | 10-K                    |   | 3/16/2017  |   | 10.14                |   |                |
| 10.15         |   | Formof Securities Purchase Agreement, dated November 17, 2017, betweenCorMedix Inc. and the investors signatory thereto.                                                                                                                                                                                                                                                                                                                                                                                          |   | 8-K                     |   | 11/13/2017 |   | 10.1                 |   |                |
| 10.16         |   | Backstop Agreement,dated November 9, 2017, between CorMedix Inc. and the investornamed therein.                                                                                                                                                                                                                                                                                                                                                                                                                   |   | 8-K                     |   | 11/13/2017 |   | 10.2                 |   |                |
| 10.17         |   | Form ofRegistration Rights Agreement, dated November 9, 2017, by andbetween CorMedix Inc. and the investor named therein.                                                                                                                                                                                                                                                                                                                                                                                         |   | 8-K                     |   | 11/13/2017 |   | 10.3                 |   |                |
| 10.18         |   | AmendmentNo. 1, dated as of December 11, 2017, to Registration RightsAgreement, dated November 9, 2017, by and between CorMedix Inc. andthe investor named therein.                                                                                                                                                                                                                                                                                                                                               |   | 8-K                     |   | 12/11/2017 |   | 10.1                 |   |                |
| 21.1          |   | List ofSubsidiaries                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               |   | 10-K                    |   | 3/27/2013  |   | 21.1                 |   |                |
| 23.1          |   | Consent ofIndependent Registered Public Accounting Firm.                                                                                                                                                                                                                                                                                                                                                                                                                                                          |   | 10-K                    |   | 3/19/2018  |   | 23.1                 |   |                |
| 31.1          |   | Certification ofPrincipal Executive Officer pursuant to Section 302 of theSarbanes-Oxley Act of 2002.                                                                                                                                                                                                                                                                                                                                                                                                             |   |                    |   |       |   |                 |   | X                   |
| 31.2          |   | Certification ofPrincipal Financial Officer pursuant to Section 302 of theSarbanes-Oxley Act of 2002.                                                                                                                                                                                                                                                                                                                                                                                                             |   |                    |   |       |   |                 |   | X                   |
| 32.1          |   | Certification ofPrincipal Executive Officer pursuant to Section 906 of theSarbanes-Oxley Act of 2002.                                                                                                                                                                                                                                                                                                                                                                                                             |   |                         |   |            |   |                      |   | X                   |
| 32.2          |   | Certification ofPrincipal Financial Officer pursuant to Section 906 of theSarbanes-Oxley Act of 2002.                                                                                                                                                                                                                                                                                                                                                                                                             |   |                         |   |            |   |                      |   | X                   |
| 101           |   | The followingmaterials from CorMedix Inc. Form 10-K for the year ended December31, 2017, formatted in Extensible Business Reporting Language(XBRL): (i) Balance Sheets at December 31, 2017 and 2016, (ii)Statements of Operations for the years ended December 31, 2017 and2016, (iii) Statements of Changes in Stockholders’ Equity forthe years ended December 31, 2017 and 2016, (iv) Statements of CashFlows for the years ended December 31, 2017 and 2016 and (v) Notesto the Financial Statements. |   | 10-K                    |   | 3/19/2018  |   | 101                  |   |                |

| *  | Confidentialtreatment has been granted for portions of this document. Theomitted portions of this document have been filed separately withthe SEC.                                                                                                                                                                                                                                                     |
|----|-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| ** | Pursuant to Rule406T of Regulation S-T, the Interactive Data Files in Exhibit 101hereto are deemed not filed or part of a registration statement orprospectus for purposes of Sections 11 or 12 of the Securities Actof 1933, as amended, are deemed not filed for purposes of Section18 of the Securities Exchange Act of 1934, as amended, andotherwise are not subject to liability under thosesections. |

|         | CORMEDIXINC.    |                                               |
|--------------|-----------------|----------------------------------------------------|
|         |            |                                               |   |
| July10, 2018 | By:   | /s/KhosoBaluch                                     |   |
|         |            | KhosoBaluch                                   |   |
|         |            | Chief ExecutiveOfficer(PrincipalExecutive Officer) |   |

|         |            |                                                              |
|--------------|-----------------|-------------------------------------------------------------------|
|         |            |                                                              |   |
| July10, 2018 | By:   | /s/RobertCook                                                     |   |
|         |            | RobertCook                                                   |   |
|         |            | Chief FinancialOfficer(PrincipalFinancial and Accounting Officer) |