Pfizer Inc.

275 North Field Drive

Lake Forest, IL 60045

July 21, 2023

Update to Pfizer Hospital U.S. Customers on the Impact of the Rocky Mount Tornado 

Dear Customer,

Our Pfizer Rocky Mount, North Carolina, manufacturing facility was damaged by a tornado on July 19, 

2023. Fortunately, all our colleagues are safe and accounted for. The Rocky Mount, North Carolina site 

is one of the largest sterile injectable facilities in the world, with more than 1.4 million square feet of 

manufacturing space on 250 acres of land in Eastern North Carolina. The facility produces a wide range 

of products that are available in small volume presentations, such as ampules, vials, and syringes.

We understand our customers have questions and may be concerned about the potential impact to 

supply and continuity of patient care. Consistent with our ongoing efforts to provide timely and transparent 

supply updates to our U.S. customers—and understanding the importance of our Rocky Mount products

to patients and health care professionals—we are sharing the following preliminary updates now, with 

the commitment to communicate additional specifics to customers as soon as possible. 

Please note the following information regarding production impact: 

• After an initial assessment, there does not appear to be any major damage to the production 

areas.

• Most of the damage was caused to the warehouse facility, which stores raw materials, packaging 

supplies, and finished medicines awaiting release by quality assurance.

• The site is closed while the damage is assessed. Crews are working around-the-clock to restore 

power, assess the structural integrity of the buildings and move finished medicines to nearby sites 

for storage and to identify sources to replace damaged raw materials and supplies. 

• We are working urgently to restart production, but do not currently have an estimated date at 

which this will occur. We will continue to keep customers apprised as we learn more.

• We are also exploring alternative manufacturing locations for production across our significant 

manufacturing presence in the U.S. and internationally and across the company’s partner 

network. 

Please note the following information related to potential supply disruptions: 

• In order to provide customers with the ability to plan for patient care today, we have identified a 

subset of Rocky Mount products by NDC that may experience continued or new supply 

disruptions in the near-term due to this weather event. This subset is based on Pfizer market 

share and inventory levels of less than 3 months across our Pfizer distribution centers and the 

wholesale chain. Note that the 3-month inventory threshold represents an abundance of caution 

based on the information available today and is not reflective of any estimates of production

restart.
© 2021 Pfizer Inc. All rights reserved. July 2023

• As we learn more from the site assessment and estimated production restart dates, we will refine 

this information and provide additional updates.

Please note the following information regarding available inventory in the distribution chain:

• Pfizer Hospital will continue to fill orders of products for which we have inventory in the distribution 

chain at 100 percent of historical levels. 

• As we learn more from the site assessment and estimated production restart dates, we will make 

necessary adjustments and provide timely updates. 

• Out of an abundance of caution due to the weather event, we recently placed allocations on the 

entire Pfizer Hospital portfolio. The allocations on non-Rocky Mount products will be lifted. 

• Please note that any products that were in limited supply status prior to the weather incident may 

still have allocations in place that are independent of the Rocky Mount situation. 

• At this time, our Availability Report on www.PfizerHospitalUS.com has not yet been updated to 

reflect the impact of the Rocky Mount tornado. Please refer to the guidance in this letter until 

further notice. 

• Please note that Pfizer does not produce COMIRNATY® (COVID-19 Vaccine, mRNA), or 

PAXLOVIDTM (nirmatrelvir tablets and ritonavir tablets) at the site. We also do not produce sterile 

injectable oncology products, SOLU-CORTEF®(hydrocortisone sodium succinate for injection, 

USP), SOLU-MEDROL®(methylprednisolone sodium succinate for injection, USP), or BICILLIN® 

L-A (penicillin G benzathine injectable suspension) at the site.

Pfizer is working closely with the FDA and other regulatory bodies and will continue to share information 

as it becomes available. In the meantime, for product availability questions, please reach out to your 

Pfizer Hospital sales representative or account executive. Alternatively, the Supply Continuity Team can 

be contacted between 7 a.m. and 5 p.m. (CT) at 1-844-646-4398 (select option 1 [Customer], then option 

3 [Supply Continuity Team]). For medical inquiries, please contact Pfizer Medical Information at 1-800-

438-1985. 

We appreciate the outpouring of cooperation and assistance from local, state, and federal governments, 

as well as our customers’ concerns for the wellbeing of our colleagues at the Rocky Mount site. As we 

do our best to minimize disruption to patient care, please keep our colleagues and the community in mind 

as we rebuild from this weather incident.

These critical medicines are of great importance for patients, and we are committed to recovering our 

supply as soon as possible. We appreciate your patience and partnership during this time. 

Thank you,

Meera Bhavsar 

Sterile Injectables Portfolio Lead 

Pfizer Hospital U.S.
© 2021 Pfizer Inc. All rights reserved. July 2023

APPENDIX: 

Pfizer Hospital Rocky Mount Products with Less Than 3 Months’ Inventory in the Distribution 

Chain 

NDC Product Description

00409-3308-03 Acetylcysteine Solution, USP 6 g/30 mL (200 mg/mL) Multiple Dose Glass Teartop Vial

00409-4346-73 Aminocaproic Acid Injection, USP 5 g/20 mL (250 mg/mL) Single Dose Plastic Fliptop 

Vial

00409-5921-01 Aminophylline Injection, USP 250 mg/10 mL (25 mg/mL) Single Dose Glass Fliptop Vial

00409-1630-10 Atropine Sulfate Injection, USP (Adult) 1 mg/10 mL (0.1 mg/mL) ANSYRTM Plastic 

Syringe

00409-4911-34 Atropine Sulfate Injection, USP (Adult) 1 mg/10 mL (0.1 mg/mL) LifeShieldTM 

ABBOJECTTM Glass Syringe (20 G x 1 1/2")

00409-1966-12 Bacteriostatic 0.9% Sodium Chloride Injection, USP 10 mL Multiple Dose LifeShieldTM 

Plastic Fliptop Vial

00409-3613-01 Bupivacaine 0.75% Spinal (bupivacaine in dextrose injection, USP) 15 mg/2 mL 

(7.5 mg/mL) Glass Ampoule

00409-1623-01 Butorphanol Tartrate Injection, USP, CIV 1 mg/mL Single Dose Glass Fliptop Vial

00409-1626-01 Butorphanol Tartrate Injection, USP, CIV 2 mg/mL Single Dose Glass Fliptop Vial

00409-1626-02 Butorphanol Tartrate Injection, USP, CIV 4 mg/2 mL (2 mg/mL) Single Dose Glass 

Fliptop Vial

00409-1631-10 Calcium Chloride Injection, USP 1 g/10 mL (100 mg/mL) ANSYRTM Plastic Syringe

00409-4928-34 Calcium Chloride Injection, USP 1 g/10 mL (100 mg/mL) LifeShieldTM ABBOJECTTM 

Glass Syringe (20 G x 11⁄2")

00409-1775-10 Dextrose Injection 25%, USP (For Infant Use) 2.5 g/10 mL (250 mg/mL) ANSYRTM 

Plastic Syringe

00409-7517-16 Dextrose Injection 50%, USP 25 g/50 mL (500 mg/mL) ANSYRTM II Plastic Syringe 

(side/side)

00409-4902-34 Dextrose Injection 50%, USP 25 g/50 mL (500 mg/mL) LifeShieldTM ABBOJECTTM 

Glass Syringe (18 G x 1 1/2")

00409-6648-02 Dextrose Injection 50%, USP 25 g/50 mL (500 mg/mL) Single Dose Glass Fliptop Vial

00409-2346-32 Dobutamine in 5% Dextrose Injection, USP 250 mg/250 mL (1 mg/mL) Flexible 

Container

00409-2347-32 Dobutamine in 5% Dextrose Injection, USP 500 mg/250 mL (2 mg/mL) Flexible 

Container

00409-3724-32 Dobutamine in 5% Dextrose Injection, USP 1,000 mg/250 mL (4 mg/mL) Flexible 

Container

00409-7809-22 Dopamine Hydrochloride in 5% Dextrose Injection, USP 400 mg/250 mL 

(1,600 mcg/mL) Flexible Container

00409-7810-22 Dopamine Hydrochloride in 5% Dextrose Injection, USP 800 mg/250 mL 

(3,200 mcg/mL) Flexible Container

00409-4933-01 Epinephrine Injection, USP 1 mg/10 mL (0.1 mg/mL) ABBOJECTTM Glass Syringe with 

Male Luer Lock Adapter and 20-Gauge protected needle

00409-9094-22 Fentanyl Citrate Injection, USP, CII 100 mcg/2 mL (50 mcg/mL) Single Dose Glass 

Fliptop Vial

00409-9093-35 Fentanyl Citrate Injection, USP, CII 250 mcg/5 mL (50 mcg/mL) Glass Ampoule

00409-7651-62 Heparin Sodium in 0.45% Sodium Chloride Injection, 12,500 USP Units/250 mL 

(50 USP Units/mL) Flexible Container

00409-7650-62 Heparin Sodium in 0.45% Sodium Chloride Injection, 25,000 USP Units/250 mL 

(100 USP Units/mL) Flexible Container
© 2021 Pfizer Inc. All rights reserved. July 2023

00409-3177-01 Lidocaine Hydrochloride and Epinephrine Injection 0.5%, USP (Lidocaine and 

Epinephrine 1:200,000) 250 mg/50 mL (5 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3178-01 Lidocaine Hydrochloride and Epinephrine Injection 1%, USP (Lidocaine and 

Epinephrine 1:100,000) 200 mg/20 mL (10 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3178-02 Lidocaine Hydrochloride and Epinephrine Injection 1%, USP (Lidocaine and 

Epinephrine 1:100,000) 300 mg/30 mL (10 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3178-03 Lidocaine Hydrochloride and Epinephrine Injection 1%, USP (Lidocaine and 

Epinephrine 1:100,000) 500 mg/50 mL (10 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3181-01 Lidocaine Hydrochloride and Epinephrine Injection 1.5%, USP (Lidocaine and 

Epinephrine 1:200,000) 450 mg/30 mL (15 mg/mL) Single Dose Glass Fliptop Vial

00409-1209-01 Lidocaine Hydrochloride 1.5% and Epinephrine Injection, USP (Lidocaine and 

Epinephrine 1:200,000) 75 mg/5 mL (15 mg/mL) Glass Ampoule

00409-3182-03 Lidocaine Hydrochloride and Epinephrine Injection 2%, USP (Lidocaine and 

Epinephrine 1:100,000) 1,000 mg/50 mL (20 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3182-01 Lidocaine Hydrochloride and Epinephrine Injection 2%, USP (Lidocaine and 

Epinephrine 1:100,000) 400 mg/20 mL (20 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3182-02 Lidocaine Hydrochloride and Epinephrine Injection 2%, USP (Lidocaine and 

Epinephrine 1:100,000) 600 mg/30 mL (20 mg/mL) Multiple Dose Glass Fliptop Vial

00409-3183-01 Lidocaine Hydrochloride and Epinephrine Injection 2%, USP (Lidocaine and 

Epinephrine 1:200,000) 400 mg/20 mL (20 mg/mL) Single Dose Glass Fliptop Vial

00409-9137-05 Lidocaine Hydrochloride Injection 1%, USP (For Cardiac Use Only) 50 mg/5 mL 

(10 mg/mL) ANSYRTM Plastic Syringe

00409-1323-05 Lidocaine Hydrochloride Injection 2%, USP (For Cardiac Use Only) 100 mg/5 mL 

(20 mg/mL) ANSYRTM Plastic Syringe

00409-4903-34 Lidocaine Hydrochloride Injection 2%, USP (For Cardiac Use Only) 100 mg/5 mL 

(20 mg/mL) LifeShieldTM ABBOJECTTM Glass Syringe (20 G x 1 1/2")

00409-4277-02 Lidocaine Hydrochloride Injection 2%, USP 1,000 mg/50 mL (20 mg/mL) Multiple Dose 

Plastic Fliptop Vial

00409-4883-01 Linezolid Injection in 0.9% Sodium Chloride 600 mg/300 mL (2 mg/mL) VisIVTM Flexible 

Container

00409-6729-03 Magnesium Sulfate in Water for Injection 20 g/500 mL (40 mg/mL) Flexible Container

00409-4031-01 Mannitol Injection, USP 12.5 g/50 mL Single Dose Glass Fliptop Vial 

(25% concentration)

00409-2305-17 Midazolam Injection, USP CIV 2 mg/2mL (1 mg/mL) Single Dose Glass Fliptop Vial

00409-2308-02 Midazolam Injection, USP CIV 10 mg/2 mL (5 mg/mL) Single Dose Glass Fliptop Vial

00409-1134-03 Morphine Sulfate Injection, USP, Cll (Preservative-Free and contains an antioxidant) 

1,000 mg/20 mL (50 mg/mL) Single Dose Glass Fliptop Vial

00409-1134-05 Morphine Sulfate Injection, USP, Cll (Preservative-Free and contains an antioxidant) 

2,500 mg/50 mL (50 mg/mL) Single Dose Glass Fliptop Vial

00409-1465-01 Nalbuphine Hydrochloride Injection 20 mg/mL Glass Ampoule

00409-1215-01 Naloxone Hydrochloride Injection, USP 0.4 mg/mL Single Dose Glass Fliptop Vial

00409-8183-01 Potassium Acetate Injection, USP 40 mEq/20 mL (2 mEq/mL) Single Dose Plastic 

Fliptop Vial

00409-6651-06 Potassium Chloride for Injection Concentrate, USP 20 mEq/10 mL (2 mEq/mL) Single 

Dose Plastic Fliptop Vial

00409-7295-01 Potassium Phosphates Injection, USP, 45 mM P/15 mL (3 mM P/mL) Single Dose 

Glass Fliptop Vial

00409-6629-02 QuelicinTM (succinylcholine chloride injection, USP) 200 mg/10 mL (20 mg/mL) Multiple 

Dose Glass Fliptop Vial

00409-9558-05 Rocuronium Bromide Injection 50 mg/5 mL (10 mg/mL) Multiple Dose Glass Fliptop Vial

00409-7299-73 Sodium Acetate Injection, USP 40 mEq/20 mL (2 mEq/mL) Single Dose Plastic Fliptop 

Vial
© 2021 Pfizer Inc. All rights reserved. July 2023

00409-3299-06 Sodium Acetate Injection, USP 200 mEq/100 mL (2 mEq/mL) Pharmacy Bulk Package 

Glass Fliptop Vial

00409-5534-14 4.2% Sodium Bicarbonate Injection, USP 5 mEq/10 mL (0.5 mEq/mL) ABBOJECT® 

Glass Syringe with Male Luer Lock Adapter and 20-Gauge protected needle

00409-5555-02 4.2% Sodium Bicarbonate Injection, USP 5 mL Fliptop Vial

00409-4916-14

7.5% Sodium Bicarbonate Injection, USP 44.6 mEq/50 mL (0.9 mEq/mL) LifeShieldTM 

ABBOJECTTM Glass Syringe with Male Luer Lock Adapter and 18-Gauge protected 

needle

00409-6637-14 8.4% Sodium Bicarbonate Injection, USP 50 mEq/50 mL (1 mEq/mL) LifeShield® 

ABBOJECT® Glass Syringe Male Luer Lock Adapter and 18-Gauge protected needle

00409-1141-02 23.4% Sodium Chloride Injection, USP 400 mEq/100 mL (4 mEq/mL) Pharmacy Bulk 

Package Glass Fliptop Vial

00409-7391-72 Sodium Phosphates Injection, USP 45 mMol/15 mL (3 mMol P/mL) Single Dose Plastic 

Fliptop Vial

00409-5816-11 Sterile Empty Vial 10 mL Glass Bottle

00409-5816-31 Sterile Empty Vial 30 mL Glass Bottle

00409-9158-01 Vitamin K1 (phytonadione injectable emulsion, USP) 10 mg/mL Glass Ampoule