F ICS 203 F Map/Chart Oth

F ICS 204 F Weather Forecast/Tides/Currents F

F ICS 205 F

F ICS 206 F

F ICS 208 F

 

 Incident Name: Salmonella Senftenberg 

/Peanut Butter/May 2022 2. Operational Period: Date From: 6/17/2022 Date To: 7/8/2022

 Time From: 1100 ET Time To: 1100 ET 

er Attachments: 

7. Prepared by: Name: Position/Title: Sharon Seelman Planning Chief Signature: Sharon Seelman 

8. Approved by Incident Commander: Name: Brooke Whitney Signature: Brooke Whitney 

ICS 202 IAP Page _____ Date/Time 06/17/2022 @ 2pm ET 

INCIDENT OBJECTIVES (ICS 202), Adapted for FDA 

Updated by FDA 2/2011 
 

(b)(4) (b)(4) (b)(4) (b)(4) (b)(4)

INCIDENT BRIEFING (ICS 201), Adapted for FDA 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident 

Number: 1067 

3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

4. Map/Sketch 

https://www.ncbi.nlm.nih.gov/pathogens/tree#Salmonella/PDG000000002.2442/PDS000031814.109?key=qUzfUUfgGvXq7cHtsvrfBoXc5Kfc8YK_nSOHe9QtBr2VbgV2FU 

5. Situation Summary and Health and Safety Briefing 

Salmonella Senftenberg (2205MLJMP-1)/Peanut Butter (suspect)/May 2022 

On 4/25/2022, the CFSAN OAO Bioinformatics Team notified CORE Signals about a potential retrospective outbreak 

involving five clinical isolates, surrounded by a large number of peanut butter and environmental isolates. The peanut 

butter and environmental isolates were collected by ( ; under contract to a 

private company) between 2014 and 2018. The samples can be identified by the acronym “ ” in NCBI and are 

noted as coming from KY. The specific identity of the manufacturer was not disclosed by . 

On 4/25/2022, after reviewing the isolates with OAO, CORE Signals reached out to CDC about the possibility of naming 

and coding the cluster. According to PulseNet, the number of clinical isolates identified over the specified time frame did 

not meet the criteria for identifying the isolates as a cluster and initiating an epidemiologic investigation. 

On 5/9/2022, the group of isolates was identified as a PulseNet cluster and was given the cluster code, 2205MLJMP-1; 

at that time there were 8 clinical isolates uploaded to PulseNet within the past 60 days. 

As of 5/19/22, this sample-initiated retrospective cluster consists of 10 cases from 8 states: GA (2), IL, MO, NC, OH, TX 

(2), VA, and WA. Cases are highly related by 0-5 SNPs (avg 1) and by 0-2 alleles by cgMLST. Isolation dates range 

from 2/20/22 to 4/24/22, with 6/10 cases occurring in April 2022. Cases range in age from 0 – 83 years, with a median 

age of 49. 70% (7/10) of cases are female. There has been one hospitalization and no reported deaths. The lag period 

for this cluster is 30 days. 



 

 

 

Updated by FDA 2/2011 

INCIDENT BRIEFING (ICS 201), Adapted for FDA 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

7. Current and Planned Objectives: 

8. Current and Planned Actions, Strategies, and Tactics: 

Time: Actions: 

6. Prepared by: Name: Ashley Grant Position/Title: Signals Team Member Signature: 

ICS 201, Page 2 Date/Time: 7/13/2022 4:32 PM EDT (b)(5) Updated by FDA 2/2011 

 

 

 

 

 

 

 

INCIDENT BRIEFING (ICS 201), Adapted for FDA 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

10. Resource Summary: 

Resource 

Resource 

Identifier 

Date/Time 

Ordered ETA 

 Arrived

Notes (location/assignment/status) 

Kim Langello Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Nicole Vaught Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

William Muszynski Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Nelson Venario Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Marianela Aponte Cruz Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

LT Sana Elassar Office of 

Human 

and 

Animal 

Foods 

Operation 
 

 

 

 

 

 

 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

10. Resource Summary: 

s - West 

(OHAFOW) 

Erin Dugan Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

Holly Miller Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

Hermie Franscisco Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

Nicole Yuen Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

Linda Stewart Office of 

Human 

and 

Animal 

Foods 

Operation 

s 

(OHAFO) 

Nicole Clausen Office of 

Human 

and 

Animal 

Foods 

Operation 

s 

(OHAFO) 
 

 

 

 

 

 

 

 

 

 

 

 

 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

10. Resource Summary: 

Monali Yajnik Office of 

Human 

and 

Animal 

Foods 

Operation 

s 

(OHAFO) 

Darcy Brillhart Office of 

Regulator 

y Science 

Jennifer Kinney Office of 

Regulator 

y Science 

ORA OSPOP 

ENFORCEMENT Recall 

Operations Branch 

Office of 

Partnershi 

ps and 

Operation 

s Policy 

(OPOP) 

Catherine Beer Office of 

Partnershi 

ps and 

Operation 

s Policy 

(OPOP) 

Kate Nagy Office of 

Human 

and 

Animal 

Foods 

Operation 

s 

(OHAFO) 

DoD Liaison 

Ginny Keys Office of 

Criminal 

Investigati 

ons (OCI) 

Heath Mott Office of 

Criminal 

Investigati 

ons (OCI) 

Claudia Ahiabor Office of 

the Chief 

Counsel 

Jason Cornell Office of 

Global 

Policy and 

Strategy 

Dana Kappel Office of 

Global 

Policy and 

Strategy 

Capt Nicole Conklin Office of 

Global 

Policy and 

Strategy 
 

 

 

 

 

 

 

 

 

 

 

 

 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

10. Resource Summary: 

Sheila VanTwyer Office of 

Operation 

s 

Office of Emergency Operations - NCCC 

Jeff Read Internatio 

nal Affairs 

Staff 

Oliver Ou Office of 

Analytics 

and 

Outreach 

CAERS staff 

Nichole Nolan Office of 

Analytics 

and 

Outreach 

CAERS staff 

Stephanie Kenez Office of 

Analytics 

and 

Outreach 

CAERS staff 

Ben Warren Office of 

Food 

Safety 

Patricia Homola Office of 

Food 

Safety 

David Rotstein CVM 

Ashley Grant Coordinat 

ed 

Outbreak 

Response 

and 

Evaluation 

Network 

(CORE) 

Alvin Crosby Coordinat 

ed 

Outbreak 

Response 

and 

Evaluation 

Network 

(CORE) 

Team Lead 

Brooke Whitney Coordinat 

ed 

Outbreak 

Response 

and 

Evaluation 

Network 

(CORE) 

Incident Lead 

Sharon Seelman Coordinat 

ed 

Outbreak 

Response 

and 

Evaluation 

Planning Chief 
 

 

 

 

 

 

 

 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

10. Resource Summary: 

Network 

(CORE) 

Johnson Nsubuga Coordinat 

ed 

Outbreak 

Response 

and 

Evaluation 

Network 

(CORE) 

Operations Chief 

Jamie Swann Coordinat 

ed 

Outbreak 

Response 

and 

Evaluation 

Network 

(CORE) 

Operations Chief 

Brenda Zimmer Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Wilbur Huggins Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Lindsay Bertling Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Joseph Cooper Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Valeria Moore Office of 

Human 
 

 

 

 

 

 

 

 

1. Incident Name: 

Salmonella Senftenberg/Peanut 

Butter/May 2022 

2. CORE Incident Number: 1067 3. Date/Time Initiated:

Date: 7/13/2022 Time: 4:32 PM 

10. Resource Summary: 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Meredith Sheridan Office of 

Human 

and 

Animal 

Foods 

Operation 

s - East 

(OHAFOE) 

Scott Jepson Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

filling in for Erin through July 9, 2022 

Kelsey Volkman Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

Travis Hunt Office of 

Human 

and 

Animal 

Foods 

Operation 

s - West 

(OHAFOW) 

ORA HAF Senior ERCs Office of 

Human 

and 

Animal 

Foods 

Operation 

s 

(OHAFO) 

orahafseniorercs@fda.hhs.gov 

Rhoma Johnson Office of 

Food 

Safety 

Gordon Davidson Office of 

Food 

Safety 

on leave until 5/21/22, Patricia covering 
 

 

 

 

 

1. Incident Name: 2. CORE Incident Number: 1067 3. Date/Time Initiated: 

Salmonella Senftenberg/Peanut Date: 7/13/2022 Time: 4:32 PM 

Butter/May 2022 

10. Resource Summary: 

Alexandra Palacios National 

Center for 

Emerging 

and 

Zoonotic 

Infectious 

Diseases 

(NCEZID) 

Laura Gieraltowski National 

Center for 

Emerging 

and 

Zoonotic 

Infectious 

Diseases 

(NCEZID)

 National CDC Comms 

Center for 

Emerging 

and 

Zoonotic 

Infectious 

Diseases 

(NCEZID) 

6. Prepared by: Name: Ashley Grant Position/Title: Signals Team Member Signature: 

ICS 201, Page 4 Date/Time: 7/13/2022 4:32 PM EDT 

Updated by FDA 2/2011 
 

Salmonella Senftenberg/Peanut Butter/May 2022 

CARA #1067 

Incident Summary Report 

July 15, 2022 

Authors: 

CORE Signals & Surveillance Team: Ashley Grant, MPH 

CORE Response Team 1: Brooke M. Whitney, PhD 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

1 
 

 

 

 

ABSTRACT 

On 4/25/2022, the CFSAN Office of Analytics and Outreach (OAO) Bioinformatics Team notified CORE 

Signals of a retrospective cluster involving five clinical isolates of Salmonella Senftenberg and a number 

of peanut butter and environmental isolates. On 5/9/2022, PulseNet coded eight isolates as a new 

cluster (2205MLJMP-1). Subsequent epidemiologic evidence collected from cases supported peanut 

butter as the vehicle. Additionally, whole genome sequencing analysis was conducted on an isolate from 

2010 collected at J.M. Smucker in Lexington, KY and found to be related to the outbreak strain. Lot 

codes of Jif peanut butter collected from confirmed cases supported exposure to peanut butter 

manufactured in Lexington, KY. FDA/ORA Human and Animal Foods Division 5 East (HAF 5E), in 

collaboration with state partners from KY, conducted an inspection with environmental sampling at J.M. 

Smucker in Lexington, KY. Environmental swabs were collected at J.M. Smucker and five states collected 

various product samples of Jif peanut butter. No Salmonella was recovered in any samples collected 

during this outbreak investigation. On 5/20/2022, J.M. Smucker Company issued a voluntary recall for 

products manufactured at the Lexington, KY facility manufactured 

(b)(4)

. Both FDA 

and CDC published webposts regarding the outbreak. Based on the epidemiologic information, 

identification of a single manufacturing facility that could be responsible, and historic laboratory 

evidence, the vehicle for this outbreak is confirmed as Jif peanut butter. This outbreak included a total 

of 21 cases from 17 states: AR (1), AZ (1), FL (1), GA (2), IL (1), IN (1), MA (1), MO (2), MI (1), NC (2), NY 

(1), OH (1), SC (1), TX (2), VA (1), WA (1), and WV (1). 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

2 
 

 

 

 

 

 

 

 

 

 

SIGNALS AND SURVEILLANCE ACTIVITIES 

On 4/25/2022, the CFSAN Office of Analytics and Outreach (OAO) Bioinformatics Team notified CORE 

Signals of a retrospective cluster involving five clinical isolates and a number of peanut butter and 

environmental isolates. The peanut butter and environmental isolates surrounding the clinical isolates 

were submitted by

(b)(4)

 and obtained under contract to a private 

company between 2014 and 2017. The minimum metadata provided with the

(b)(4)

 isolates identified KY 

(b)(4)

as the site of origin. At the time, the specific identity of the manufacturer was not disclosed by . 

On 4/25/2022, after reviewing the cluster with OAO, CORE Signals reached out to CDC about the 

possibility of coding a cluster for an epidemiologic investigation. At the time, according to PulseNet, the 

number of clinical isolates identified over the specified time frame did not meet their threshold for 

identifying the isolates as a cluster and initiating an epidemiologic investigation. However, over the next 

two weeks, additional clinical isolates were uploaded to NCBI, and on 5/9/2022, PulseNet did code these 

isolates as a new cluster (2205MLJMP-1). At the time the cluster was named, there were 8 clinical 

isolates uploaded to PulseNet within the past 60 days. 

At the time of transfer, on 5/19/2022, this sample-initiated retrospective cluster consisted of 10 cases 

from 8 states: GA (2), IL, MO, NC, OH, TX (2), VA, and WA. Cases were highly related by 0-5 SNPs (avg 1) 

and 0-2 alleles by cgMLST. Isolation dates ranged from 2/20/2022 to 4/24/2022, with 6/10 cases 

occurring in April 2022. Cases ranged in age from 0 to 83 years, with a median age of 49. 70% (7/10) of 

cases were female. At the time of transfer, there had been one hospitalization and no reported deaths. 

The lag period for this cluster was reported as 30 days. 

Because the

(b)(4)

 peanut butter and environmental samples were reported as being from KY, CORE 

Signals reviewed open-source media and FDA firm information, and determined that J.M. Smucker 

manufactures JIF brand peanut butter at a facility in Lexington, KY. Upon review of this firm’s 

inspectional history, CORE Signals noted that during an FDA inspection in 2010, environmental swabbing 

at this facility yielded Salmonella Senftenberg. CORE Signals requested a comparison of this historical 

isolate to the current clinical clusters. The isolate was subsequently analyzed by OAO and reported to be 

a match to the peanut butter and environmental

(b)(4)

 isolates identified in NCBI from 2014 to 2017, and 

to the clinical isolates included in the current cluster. Specifically, the 2010 sample was noted to be 

related to the 

(b)(4)

 isolates by 0-24 SNPs (mean 7.33 SNPs), and to the 2022 cluster of clinical isolates 

(2205MLJMP-1) by 14-17 SNPs (mean 15.2 SNPs). Based on the intervening time period of 12 years 

between the collection of the 2010 sample (#549178) and the clinical isolates, and with an average 

assumption of genetic evolution over time of 1-2 snps, OAO concluded that sample 549178 matched the 

clinical isolates in illness cluster 2205MLJMP-1. 

FDA and the state of KY (under state contract) inspected the ‘J.M. Smucker’ Lexington, KY facility several 

times following the identification of the 2010 positive Salmonella sample. Swabbing and samples had 

not been collected by regulatory authorities since 2011 and all subsequent inspections were classified 

‘NAI’. ‘J.M. Smucker’, Lexington, KY facility (FEI: 1021607) is the primary manufacturer of JIF brand 

peanut butter and this location was identified by the lot code “425”. 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

3 
 

 

 

 

 

 

 

 

 

 

CORE Signals summarized the firm research and related FDA sample for CDC, suggested that the 

epidemiologic investigation include questions about peanut butter, and identified JIF brand peanut 

butter as an item of particular interest. Preliminary exposure information reported by CDC on 5/18/2022 

indicated 4/4 cases reported peanut butter and 3/4 specifically reported JIF brand (variety not 

specified). 

Based on the WGS link between the clinical and peanut butter isolates, combined with preliminary 

epidemiological evidence provided by CDC, peanut butter was considered the suspect vehicle associated 

with this retrospective outbreak. As this determination was made and based on the whole genome 

sequencing evidence linking FDA’s 2010 sample to the current outbreak, ORA initiated an inspection at 

J.M. Smucker on 5/19/2022. 

This incident was transferred to CORE Response Team 1 based on the following rationale: 

x This was a retrospective illness cluster of Salmonella Senftenberg, which at the time, was 

considered ongoing. 

x Based on WGS data, inspectional history, and preliminary epidemiologic information obtained 

by CDC, CORE Signals (in collaboration with CDC) identified JIF brand peanut butter 

manufactured at the Lexington, KY ‘JM Smucker’ facility as the suspect vehicle for this incident. 

x Response coordination was needed for follow-up at the manufacturing facility and to coordinate 

product and regulatory actions. 

x Salmonella and peanut butter are a repeat pathogen/commodity pair and are of significant 

interest to the FDA foods program. 

EPIDEMIOLOGY 

In total, this outbreak included 21 cases from 17 states (AR (1), AZ (1), FL (1), GA (2), IL (1), IN (1), MA (1), 

MI (1), MO (2), NC (2), NY (1), OH (1), SC (1), TX (2), VA (1), WA (1), and WV (1)). Isolation dates range 

from 2/20/2022 to 5/24/2022 while reported onset dates range from 2/19/2022 to 5/23/2022. Ages 

ranged from <1 to 85 years (median: 59 years), and 75 % of cases were female. Of 13 patients with 

outcome information, four were hospitalized; there were no reported deaths. All clinical isolates were 

related at 0–2 alleles by cgMLST with common allele code SALM1.0 - 6738.1.5.21.2. A case was defined 

as infection with Salmonella Senftenberg whose isolate was closely related by whole genome 

sequencing within 0–2 alleles and an isolation date from 2/20/2022 – 5/24/2022. 

Given the proximity in NCBI to several peanut butter isolates, CDC and FDA initially suspected peanut 

butter as a vehicle of interest. CDC held a state call and deployed a peanut butter supplemental 

questionnaire on 5/20/2022. Of 13 patients with information, all reported Jif brand peanut butter 

(100%). 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

4 
 

 

 

 

 

CDC closed this investigation on 6/28/2022 as an outbreak with a confirmed vehicle of peanut butter. 

This investigation will be reported to NORS with ID 2205MLJMP-1. CDC provided a summary of the 

outbreak to state partners on 7/14/2022. 

LABORATORY 

FDA collected an environmental sample consisting of 206 environmental swabs, and state partners 

collected at least 14 product samples for Salmonella testing. Salmonella was not isolated from any of 

the state or FDA samples. 

FDA Samples 

On 5/20/2022, HAF 5E collected 206 environmental swabs at J.M. Smucker Company in Lexington, KY 

(Sample #1139991). These were shipped for Saturday Delivery to NFFL for Salmonella analysis. On 

5/23/2022, ORA/ORS notified CORE that 27 of the 206 subs were negative for Salmonella, with the 

balance pending. On 5/24/2022, ORA/ORS notified CORE that two of the sub samples were Cannot Rule 

Out (CRO) for Salmonella. The two subs that were initially CRO were Sub# 53 = Line 2 Label exit 

conveyor (Zone 2) and Sub# 195 = 7C Dock (Construction) wheel to compost jack (Zone 3). Ultimately, on 

5/31/2022, ORA ORS reported the 206 environmental swabs collected at J.M. Smucker Company in 

Lexington, KY (Sample #1139991) tested negative for Salmonella. 

State Samples 

Five states collected product samples. CORE requested state sampling of product only in specific 

scenarios, as outlined by the following guidance provided in Operational Briefing #1 on 5/24/2022: 

Sampling guidance for FDA state partners – Complaints 

x Determine if the complainant has a recalled product or not. 

x If the complaint has a reported case of Salmonella with health care provider visit, AND a nonrecalled Jif product, please ask them to hold the product. 

x If the state has resources, please analyze the sample for Salmonella. If resources do not allow, 

please contact your ERC to consider transfer of the consumer product to FDA for testing. 

Samples associated with confirmed cases of Salmonella serotype Senftenberg will priority. 

x We believe these steps will ensure a reasonable number of product samples of greatest interest, 

but we also recognize that some confirmed Salmonella cases may not be related to peanut 

butter consumption. 

Sampling guidance for state partners – Confirmed cases in outbreak 

x We know there is interest in sampling product from confirmed cases in the outbreak. CORE is 

not specifically requesting this be conducted on recalled products. 

x However, if a state does move forward with testing products, please keep your ERC aware of the 

results. 

x If a positive is found, FDA is interested in enumerating the sample in a research capacity. 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

5 
 

 

 

 

 

 

Ohio 

The Ohio Department of Health (ODH) collected a product later included the recall that was consumed 

by a case. Based on photos provided, the lot code was 20174250202:30 with best if used by date Jan 17 

2023. ODH analyzed this product for Salmonella. On 5/31/2022, reported the leftover Jif peanut butter 

from the OH case tested negative for Salmonella. 

On 6/1/2022, HAF 5E relayed results of sampling conducted by OH Department of Agriculture; eight 

samples of Jif peanut butter unrelated to any cases were negative for Salmonella, E. coli, and Listeria 

monocytogenes. Further details of the collected products were not received or sought. 

Texas 

On 5/24/2022, HAF 3W (DAL) alerted CORE that TX DSHS collected a case-associated sample of Jif with 

lot number 2024 425 01 13:26 for Salmonella analysis. 

New York 

On 5/25/2022, NY DOH collected two jars leftover from a NY case included in the outbreak for 

Salmonella analysis. The jar consumed prior to symptom onset has a lot code of 20174250205:34 and 

the additional jar has a lot code of 2033006111256. On 6/3/2022, HAF 1E (NYK) relayed that both jars 

were negative for Salmonella. 

North Carolina 

On 5/26/2022, NC state partners collected a sample of peanut butter from an outbreak case. Based on 

previous information provided by CDC, the case had lots 13514250209:23 and 11534250103:56. 

Arizona 

AZ tested product that was not recalled and it was negative; associated case not in outbreak (different 

serotype), but we had been following these consumer complaint-related activities 

Whole Genome Sequencing 

On 5/18/2022, CFSAN OAO created a WGS report that included ten clinical isolates in the outbreak with 

the following interpretation: 

One Salmonella enterica sample number 549178 subsample was analyzed (blue). It matches a 

large number of peanut butter and environmental isolates that were submitted to NCBI (mean 

7.33 SNPs). It is also mean 15.2 SNPs from the clinical isolates in illness cluster 2205MLJMP-1 

(red). Since there is a span of approximately 12 years between the collection of 549178 and the 

clinical isolates, the results show that 549178 matches the clinical isolates in illness cluster 

2205MLJMP-1. Predicted serotype: Senftenberg. 

Any updates to this information can be viewed in NCBI by searching cluster PDS000031814.109. Sample 

549178 was an FDA isolate collected on 6/22/2010 from the J.M. Smucker facility in Lexington, KY. The 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

6 
 

additional environmental and peanut butter isolates referenced above were labeled as from KY and 

were collected in 2014 (111 isolates), 2015 (1 isolate), 2016 (3 isolates) and 2017 (2 isolates). A verbal 

confirmation was provided to FDA that these isolates also originated from the J.M. Smucker facility in 

Lexington, KY. 

J.M. Smucker reported third party testing had identified Salmonella in both environmental and product 

sampling; however, the firm did not request isolation, speciation, serotyping, or WGS for the positive 

samples. Combined with the lack of isolation of Salmonella from FDA sampling, there is no 

contemporary non-human WGS information to be incorporated into the overall WGS analysis. 

Laboratory Conclusions 

While there was historic laboratory evidence that linked this firm to the outbreak strain, no Salmonella 

was identified in environmental sampling conducted at the firm or identified by states through product 

sampling conducted. 

TRACEBACK 

A traditional traceback investigation through the distribution chain was not conducted. Rather, 

traceback initiatives were based on lot code information collected from confirmed cases in the 

outbreak. An explanation of the lot coding for Jif peanut butter was provided in multiple Establishment 

Investigation Reports (EIRs) for the J.M. Smucker facility in Lexington, KY. The lot code begins with a 

(b)(4)

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report 

contains protected, privileged, confidential, and commercial information and may only be released outside FDA with appropriate 

redaction. This document was prepared by the Coordinated Outbreak Response and Evaluation Network (CORE). 

7 

Case ID State Size 

(oz) 

EXP. date Lot Peanut Butter 

Description 

Testing / Results? 

NC___MB220228-0036-001 NC 16 12/17/2023 13514250209:23 Jif Creamy no 

16 6/2/2023 11534250103:56 Jif Creamy Yes/negative 

OH___2022005733 OH 40 Not reported 20174250202:30 Low Sodium Jif 

Natural Creamy 

Yes/negative 

AR__AR2209800000124 AR 40 Not reported 2058425091148 Jif Creamy No 

IL2__S220089781 MO 40 Not reported 20374250200:48 Jif natural creamy No 

TX___TXACB2200840 TX 16 1/24/2024 2024 425 0113:26 Jif Creamy Yes/negative 

NY___IDR2200019080-01-00 NY 40 1/17/2023 20174250205:34 Jif Natural Creamy Yes/negative 

40 2/2/2023 2033006111256 Jif Natural Creamy Yes/negative 

WA___WA0786368 WA 28 Not reported 1349425, (only first 

7 digits provided) 

Jif Crunchy Peanut Butter 

No 

Not reported 2008425 (only first 7 

digits provided) 

Jif Crunchy Peanut Butter 

No 

AZ___AZ00161524 AZ Not reported 2026425 (only first 7 

digits provided) 

Jif Creamy No 

WV___E22M015780 WV Not reported 20264250304 Not Reported No VA_R220407058 VA 16 Not Reported Not Reported Jif Reduced Fat 

Creamy 

No 

IL2__S220062394 IL 40 Not Reported Not Reported Jif Creamy Peanut 

Butter 

no 

Only for use by internal FDA, FDA Commissioned Officials, and those with signed 20.88 agreements with FDA. This report contains protected, privileged, co

and may only be released outside FDA with appropriate redaction. This document was prepared by the Coordinated Outbreak Res
 

 

 

 

 

 

 

 

 

CFSAN Biostatistics and Bioinformatics Sta ̇ WGS Analysis 

Report 

Report Title: Report_220518_Se2205MLJMP-1_220518

Firm Name:

Pathogen: Salmonella

Sample or Facts IDs:

549178

Date Generated: 18 May, 2022

Bioinformatician: Arthur Pightling

WGS Interpretation:

One Salmonella enterica sample number 549178 subsample was analyzed (blue). It matches a large number

of peanut butter and environmental isolates that were submitted to NCBI (mean 7.33 SNPs). It is also

mean 15.2 SNPs from the clinical isolates in illness cluster 2205MLJMP-1 (red). Since there is a span of

approximately 12 years between the collection of 549178 and the clinical isolates, the results show that

549178 matches the clinical isolates in illness cluster 2205MLJMP-1. Predicted serotype: Senftenberg.

NCBI SNP Cluster ID(s): PDS000031814.109

Cluster(s) can be monitored by searching for ID here.

CFSAN SNP Pipeline Version: v2.2.1.

See below for phylogenetic clusters (if they were generated).

References

• Information about the CFSAN SNP Pipeline can be found https://peerj.com/articles/cs-20/.

• Information on the interpretation of SNP distances and those clusters can be found

https://www.frontiersin.org/articles/10.3389/fmicb.2018.01482/full.

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