FORM 10-Q

                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C.  20549

                   QUARTERLY REPORT UNDER SECTION 13 OR 15(D)
                     OF THE SECURITIES EXCHANGE ACT OF 1934



For the quarter ended March 31, 2000              Commission File Number 0-11172

              FIRST CITIZENS BANCORPORATION OF SOUTH CAROLINA, INC.
              -----------------------------------------------------
             (Exact name of registrant as specified in its charter)

       South Carolina                                       57-0738665
-----------------------------------         ------------------------------------
 (State or other jurisdiction of            (IRS  Employer  Identification  No.)
  incorporation or organization)

        1230  Main  Street
     Columbia,  South  Carolina                                  29201
--------------------------------------------------------------------------------
(Address  of  principal  executive  offices)                   (Zip  Code)

Registrant's  telephone  number,  including  area  code   (803)  733-3456
                                                          ---------------

                                   No  Change
--------------------------------------------------------------------------------
                    (Former name, former address and former
                   fiscal year, if changed since last report.)

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding  12  months  (or  for such shorter period that the Registrant was
required  to  file  such  reports),  and  (2)  has  been  subject to such filing
requirements  for  the  past  90  days.  YES  [ X ]  NO  [   ]

Indicate  the  number  of  shares outstanding of each of the issuer's classes of
common  stock,  as  of  the  latest  practicable  date.

               Class                       Outstanding  at  April  30,  2000
               -----                       ---------------------------------
Voting Common Stock, $5.00 Par Value                900,676  Shares
Non-Voting Common Stock, $5.00 Par Value             36,409  Shares


<PAGE>
<TABLE>
<CAPTION>
PART  I  -  FINANCIAL  INFORMATION
ITEM  1.  FINANCIAL  STATEMENTS

FIRST  CITIZENS  BANCORPORATION  OF  SOUTH  CAROLINA,  INC.  AND  SUBSIDIARIES
-------------------------------------------------------------------------------------------------------

CONSOLIDATED  STATEMENTS  OF CONDITION - UNAUDITED (DOLLARS IN THOUSANDS, EXCEPT PAR  VALUE)

                                                                 MARCH 31,    December 31,    March 31,
                                                                   2000           1999          1999
                                                                -----------  --------------  -----------
<S>                                                             <C>          <C>             <C>
ASSETS
Cash and due from banks                                         $  118,473   $     151,897   $  107,001
Federal funds sold                                                  36,500          37,400       87,100

Investment securities:
  Held-to-maturity, at amortized cost                               33,752          40,666       24,413
  Available-for-sale, at fair value                                674,491         522,326      600,821
                                                                -----------  --------------  -----------
Total investment securities                                        708,243         562,992      625,234
                                                                -----------  --------------  -----------

Gross loans                                                      1,925,368       1,854,520    1,598,043
  Less: Allowance for loan losses                                  (34,265)        (32,972)     (28,760)
                                                                -----------  --------------  -----------
Net loans                                                        1,891,103       1,821,548    1,569,283
                                                                -----------  --------------  -----------
Premises and equipment                                              86,087          84,395       80,384
Interest receivable                                                 17,422          15,135       14,593
Intangible assets                                                   25,823          19,256       16,202
Other assets                                                        34,431          33,962       22,632
                                                                -----------  --------------  -----------
     TOTAL ASSETS                                               $2,918,082   $   2,726,585   $2,522,429
                                                                ===========  ==============  ===========

LIABILITIES AND STOCKHOLDERS' EQUITY
LIABILITIES
Deposits:
  Demand                                                        $  427,074   $     396,781   $  361,176
  Time and savings                                               1,887,519       1,825,252    1,678,972
                                                                -----------  --------------  -----------
Total deposits                                                   2,314,593       2,222,033    2,040,148
Securities sold under agreements to repurchase and federal
   funds purchased                                                 324,969         230,904      236,725
Long-term debt                                                      50,963          50,963       50,000
Other liabilities                                                   25,649          22,612       18,118
                                                                -----------  --------------  -----------
     TOTAL LIABILITIES                                           2,716,174       2,526,512    2,344,991
                                                                -----------  --------------  -----------

STOCKHOLDERS' EQUITY:
  Preferred stock                                                    3,248           3,282        3,282
  Non-voting common stock - $5.00 par value, authorized
    1,000,000; issued and outstanding March 31, 2000,
    December 31, 1999 and March 31, 1999 - 36,409                      182             182          182
  Voting common stock - $5.00 par value, authorized 2,000,000;
    issued and outstanding March 31, 2000 - 900,870
   December 31, 1999 - 906,205; and March 31, 1999 - 882,766         4,504           4,531        4,414
  Surplus                                                           65,081          65,081       55,000
  Undivided profits                                                128,317         123,328      107,381
  Accumulated other comprehensive income, net of taxes                 576           3,669        7,179
                                                                -----------  --------------  -----------
     TOTAL STOCKHOLDERS' EQUITY                                    201,908         200,073      177,438
                                                                -----------  --------------  -----------
     COMMITMENTS AND CONTINGENCIES                                      --              --           --
     TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY                 $2,918,082   $   2,726,585   $2,522,429
                                                                ===========  ==============  ===========
</TABLE>


                                     PAGE 2
<PAGE>
<TABLE>
<CAPTION>
FIRST  CITIZENS  BANCORPORATION  OF  SOUTH  CAROLINA,  INC.  AND  SUBSIDIARIES
==============================================================================
CONSOLIDATED  STATEMENTS  OF  INCOME  -  UNAUDITED
(DOLLARS  IN  THOUSANDS-EXCEPT  PER  SHARE  DATA)

                                                        FOR THE
                                                  THREE MONTHS ENDED
                                                       MARCH 31,
                                                  ------------------
                                                    2000      1999
                                                  --------  --------
<S>                                               <C>       <C>
INTEREST INCOME:
  Loans, including fees                           $ 38,881  $ 32,626
  Interest on investment securites:
    Taxable                                          8,184  $  7,757
                                                       390       342
  Federal funds sold                                   910     1,159
                                                  --------  --------
Total interest income                               48,365    41,884
                                                  --------  --------
INTEREST EXPENSE:
  Deposits                                          17,014    14,520
  Securities sold under agreements to repurchase
    and federal funds purchased                      4,127     2,877
  Long-term debt                                     1,050     1,031
                                                  --------  --------
Total interest expense                              22,191    18,428
                                                  --------  --------

Net interest income                                 26,174    23,456
Provision for loan losses                            1,559       663
                                                  --------  --------
Net interest income after
  provision for loan losses                         24,615    22,793
                                                  --------  --------

NONINTEREST INCOME:
  Service charges on deposit accounts                5,080     4,100
  Commission and fees from fiduciary activities        610       395
  Fees for other customer services                     611       617
  Mortgage servicing fees                              549       549
  Bankcard discount and fees                         1,004       814
  Insurance premiums earned                            358       402
  Gain on sale of investment securities                 31         -
  Other                                                183       632
                                                  --------  --------
Total noninterest income                             8,426     7,509
                                                  --------  --------
NONINTEREST EXPENSE:
  Salaries and employee benefits                    11,291    10,386
  Net occupancy expense                              1,671     1,574
  Furniture and equipment expense                    1,616     1,465
  Amortization of intangibles                        1,378     1,411
  Bankcard processing expense                        1,061       933
  Data processing expense                            1,873     1,722
  Professional services                                494       487
  Other                                              3,947     3,935
                                                  --------  --------
Total noninterest expense                           23,331    21,913
                                                  --------  --------

Income before income tax expense                     9,710     8,389
Income tax expense                                   3,350     2,924
                                                  --------  --------
NET INCOME                                        $  6,360  $  5,465
                                                  ========  ========

----------------------------------------------------------------------
======================================================================
----------------------------------------------------------------------

NET INCOME PER COMMON SHARE -
BASIC AND DILUTED                                 $   6.73  $   5.89
WEIGHTED AVERAGE COMMON
SHARES OUTSTANDING-BASIC AND DILUTED               938,902   919,835
</TABLE>


                                     PAGE 3
<PAGE>
<TABLE>
<CAPTION>
FIRST  CITIZENS  BANCORPORATION  OF  SOUTH  CAROLINA,  INC.  AND  SUBSIDIARIES

------------------------------------------------------------------------------------------------------------------

CONSOLIDATED  STATEMENTS  OF  CHANGES  IN STOCKHOLDERS' EQUITY AND COMPREHENSIVE INCOME-  UNAUDITED
(DOLLARS  IN  THOUSANDS)

                                               Non-                                       Accumulated      Total
                                              Voting    Voting                               Other         Stock-
                                  Preferred   Common    Common              Undivided    Comprehensive    holders'
                                    Stock      Stock    Stock    Surplus     Profits     Income/(Loss)     Equity
                                 -----------  -------  --------  --------  -----------  ---------------  ----------
<S>                              <C>          <C>      <C>       <C>       <C>          <C>              <C>
Balance at December 31, 1998     $    3,282   $   182  $ 4,426   $ 55,000  $  102,888   $        8,397   $ 174,175
Comprehensive income:
  Net income                                                                    5,465                        5,465
  Change in unrealized losses
     on investment securities
     available-for-sale, net of
     benefit of $2,422                                                                          (1,218)     (1,218)
                                                                                                         ----------
Total comprehensive income                                                                                   4,247
                                                                                                         ----------
Reacquired voting common stock                             (12)                  (930)                        (942)
Preferred stock dividends                                                         (42)                         (42)
                                 -----------  -------  --------  --------  -----------  ---------------  ----------
Balance at March 31, 1999             3,282       182    4,414     55,000     107,381            7,179     177,438
Comprehensive income:
  Net income                                                                   19,181                       19,181
  Change in unrealized losses
     on investment securities
     available-for-sale, net of
     benefit of $120                                                                            (3,510)     (3,510)
                                                                                                         ----------
Total comprehensive income                                                                                  15,671
                                                                                                         ----------
Reacquired voting common stock                             (54)                (3,105)                      (3,159)
Stock issued in acquisition                                171     10,081                                   10,252
Preferred stock dividends                                                        (129)                        (129)
                                 -----------  -------  --------  --------  -----------  ---------------  ----------
Balance at December 31, 1999          3,282       182    4,531     65,081     123,328            3,669     200,073
Comprehensive income:
  Net income                                                                    6,360                        6,360
  Change in unrealized losses
     on investment securities
     available-for-sale, net of
     benefit of $1,218                                                                          (3,093)     (3,093)
                                                                                                         ----------
Total comprehensive income                                                                                   3,267
                                                                                                         ----------
Reacquired preferred stock              (34)                                        6                          (28)
Reacquired voting common stock                             (27)                (1,335)                      (1,362)
Preferred stock dividends                                                         (42)                         (42)
                                 -----------  -------  --------  --------  -----------  ---------------  ----------
Balance at March 31, 2000        $    3,248   $   182  $ 4,504   $ 65,081  $  128,317   $          576   $ 201,908
                                 ===========  =======  ========  ========  ===========  ===============  ==========
</TABLE>


                                     PAGE 4
<PAGE>
FIRST  CITIZENS  BANCORPORATION  OF  SOUTH  CAROLINA,  INC.  AND  SUBSIDIARY

CONSOLIDATED  STATEMENTS  OF  CASH  FLOWS  -  UNAUDITED  (DOLLARS  IN THOUSANDS)

<TABLE>
<CAPTION>
                                                                                 For the three months ended
                                                                                          March  31,
                                                                                   ---------------------
                                                                                      2000       1999
                                                                                   ----------  ---------
CASH FLOWS FROM OPERATING ACTIVITIES:
<S>                                                                                <C>         <C>
  Net income                                                                       $   6,360   $  5,465
  Adjustments to reconcile net income to net cash provided
    by operating activities:
    Provision for loan losses                                                          1,559        663
    Depreciation and amortization                                                      3,370      3,090
    (Accretion) amortization of investment securities                                   (731)       137
    Deferred income tax benefit                                                         (134)    (6,874)
    Gains on sales of premises and equipment                                               0       (150)
    (Increase) decrease in interest receivable                                        (2,287)       261
    Increase in interest payable                                                       1,913        598
    Origination of mortgage loans held-for-sale                                      (20,233)   (40,738)
    Proceeds from sales of mortgage loans held-for-sale                               21,134     46,532
    Gains on sales of mortage loans held-for-sale                                        (64)      (223)
    Gains on call or sale of investment securities                                       (31)         0
    Decrease in other assets                                                           1,376      8,949
    Increase in other liabilities                                                      1,114        116
                                                                                   ----------  ---------
  NET CASH PROVIDED BY OPERATING ACTIVITIES                                           13,346     17,826

CASH FLOWS FROM INVESTING ACTIVITIES:
    Net increase in loans                                                            (38,504)   (30,754)
    Calls, maturities and prepayments of investment securities held-to-maturity        7,881        934
    Purchases of investment securities held-to-maturity                                 (205)      (290)
    Calls, maturities and prepayments of investment securities available-for-sale     63,308     79,802
    Purchases of investment securities available-for-sale                           (220,231)   (83,862)
    Decrease (increase) in federal funds sold                                            900    (23,100)
    Proceeds from sales of premises and equipment                                          0      2,512
    Purchases of premises and equipment                                               (2,158)    (5,313)
    (Increase) decrease in other real estate owned                                       (39)       195
    Increase in intangible assets                                                        (87)      (444)
    Purchase of institutions, net of cash acquired                                    24,478          0
                                                                                   ----------  ---------
      NET CASH USED IN INVESTING ACTIVITIES                                         (164,657)   (60,320)

CASH FLOWS FROM FINANCING ACTIVITIES:
    Net increase in deposits                                                          25,254      2,661
    Increase in federal funds purchased and securities sold
      under agreements to repurchase                                                  94,065     32,023
    Cash dividends paid                                                                  (42)       (42)
    Cash paid to reacquire preferred stock                                               (28)         0
    Cash paid to reacquire common stock                                               (1,362)      (942)
                                                                                   ----------  ---------
      NET CASH PROVIDED BY FINANCING ACTIVITIES                                      117,887     33,700

NET DECREASE IN CASH AND DUE FROM BANKS                                              (33,424)    (8,794)
CASH AND DUE FROM BANKS AT BEGINNING OF PERIOD                                       151,897    115,795
                                                                                   ----------  ---------
CASH AND DUE FROM BANKS AT END OF PERIOD                                           $ 118,473   $107,001
                                                                                   ==========  =========
</TABLE>


                                     PAGE 5
<PAGE>
NOTES  TO  THE  CONSOLIDATED  FINANCIAL  STATEMENTS  (Unaudited)

SUMMARY  OF  SIGNIFICANT  ACCOUNTING  POLICIES

A  summary  of  the  significant  accounting  policies  of  First  Citizens
Bancorporation of South Carolina, Inc. ("Bancorporation") is set forth in Note 1
to  the  Consolidated  Financial Statements in Bancorporation's Annual Report on
Form 10-K for 1999.  The significant accounting policies used during the current
quarter  are  unchanged  from  those  disclosed  in  the  1999  Annual  Report.

Basis  of  presentation

The  preceding  consolidated  financial  statements  and  the  notes thereto are
unaudited;  however,  in  the  opinion of management, all adjustments comprising
normal  recurring accruals necessary for a fair presentation of the consolidated
financial  statements have been recorded.  Certain amounts in prior periods have
been  reclassified  to  conform  to  the  2000  presentation.


Acquisitions  (Dollars  in  thousands)

On  March  10,  2000,  three  branch  locations were acquired from another South
Carolina  financial  institution.  First  Citizens  Bank  and  Trust  of  South
Carolina,  Inc.  ("Bank")  acquired  deposits  of $67,983, loans of $32,632, and
goodwill  of  $7,864  in  connection  with  this  acquisition.  No  goodwill
amortization  was  recorded  for the period ended March 31, 2000 related to this
acquisition.

On August 20, 1999, Bancorporation acquired The Exchange Bank of South Carolina,
a  banking  corporation located in Kingstree, South Carolina.  The total cost of
the  acquisition,  recorded  as  a  purchase,  was  $15,750.

The  breakdown  of  the  purchase  price  is  as  follows:

     Cash                                               $  4,535
     5  year  Bancorporation  notes  @  7.50%                 90
     10  year  Bancorporation  notes  @  7.75%               873
     Bancorporation  stock  -  34,174  shares             10,252
                                                        --------
     Total  consideration                               $ 15,750
                                                        ========

Goodwill  amortization  related  to this acquisition for the quarter ended March
31,  2000,  was  $53.

Subsequent  events

On  April 26, 2000, Bancorporation's Board of Directors declared a $.25 dividend
on  common  stock  to  shareholders of record on May 5, 2000, payable on May 15,
2000.


Item  2.  Management's  Discussion  and  Analysis  of  Results of Operations and
Financial  Condition

                              RESULTS OF OPERATIONS

Summary  (Dollars  in  thousands)

Net  income  for  the quarter ended March 31, 2000 totaled  $6,360, or $6.73 per
common  share.  Net  income for the quarter ended March 31, 1999 totaled $5,465,
or  $5.89  per  common  share.

The  primary factors affecting the increase in net income were a $1,822 or 7.99%
increase  in  net interest income after provision for loan losses, and a $917 or
12.21%  increase  in noninterest income.  These favorable changes were partially
offset  by  a  $1,418  or  6.47%  increase in noninterest expense, and a $426 or
14.57%  increase  in  income  tax  expense.

Return  on  average  stockholders' equity and average assets are key measures of
earnings  performance.  Return  on  average  stockholders' equity for the period
ended  March  31,  2000 and March 31, 1999 were 12.50% and 12.35%, respectively.
The  increase  was  primarily  the  result  of  improvement in return on average
assets.  Return  on average assets for the period ended March 31, 2000 and March
31,  1999  were  .90%  and  .87%,  respectively.  The increase was primarily the
result  of  an  18  basis point improvement in the noninterest margin to average
assets.  This  favorable change was partially offset by a 13 basis point decline
in  the  net  interest  margin  after provision to average assets.  Net interest
income  is  discussed  further  in  the  following  section.


                                     PAGE 6
<PAGE>
Table  1  provides  summary information on selected average balances and ratios.
Table  1:  Selected  Summary  Information  (dollars  in  thousands)

<TABLE>
<CAPTION>
                                                                           As of and for the
                                                                          three months ended
                                                                                March 31,
                                                                        ------------------------
Selected average balances:                                                  2000        1999
                                                                        -----------  -----------
<S>                                                                     <C>          <C>
Total assets                                                            $2,817,140   $2,518,229
Interest-earning assets                                                  2,575,796    2,304,390
Investment securities                                                      641,689      626,107
Loans                                                                    1,868,559    1,579,202
Deposits                                                                 2,236,351    2,016,090
Noninterest-bearing deposits                                               399,327      352,031
Interest-bearing deposits                                                1,837,024    1,664,059
Interest-bearing liabilities                                             2,191,200    1,972,900
Stockholders' equity                                                       203,534      176,979

Selected ratios:
Return on average assets                                                       .90%         .87%
Return on average stockholders   equity                                      12.50%       12.35%
Return on average common stockholders'                                        7.11%        6.90%
   equity
Net yield on average interest-earning assets                                  4.15%        4.19%
   (tax equivalent)
Average loans to average deposits                                            83.55%       78.33%
Nonperforming assets to total loans                                            .17%         .18%
Allowance for loan losses to total loans                                      1.78%        1.80%

Allowance for loan losses to nonperforming                                  10.90x       10.22x
   assets
Average stockholders' equity to average total                                 7.22%        7.03%
   assets
Total risk-based capital ratio                                               13.20%       14.38%
Tier I risk-based capital ratio                                              11.96%       13.12%
Tier I leverage ratio                                                         8.16%        8.26%
</TABLE>


Net  interest  income  (Dollars  in  thousands)

Net  interest  income  represents  the  principal  source  of  earnings  for
Bancorporation.  Table  2  compares average balance sheet items and analyzes net
interest  income on a tax equivalent basis for the quarters ended March 31, 2000
and  1999.


                                     PAGE 7
<PAGE>
<TABLE>
<CAPTION>
Table  2:  Comparative  Average  Balance  Sheets  and  Taxable  Equivalent  Rate/Volume  Variance  (Dollars  in  thousands)

                                          As of and for the three months ended March 31,

                                                                                     Yield/Average  Change Due to(2)
                                                 Average Balance    Interest Inc/Exp(1)   Rate      ----------------     Net
                                             ----------------------  ----------------  ----------   Yield              Increase
                                                2000        1999      2000     1999    2000  1999   /Rate    Volume   (Decrease)
                                             ----------  ----------  -------  -------  ----  ----  -------  --------  -----------
<S>                                          <C>         <C>         <C>      <C>      <C>   <C>   <C>      <C>       <C>
Interest-earning assets:
Loans (3)                                    $1,868,559  $1,579,202  $39,061  $32,773  8.41  8.42  $  204   $ 6,084   $    6,288
Investment securities:
  Taxable                                       612,553     601,830    8,184    7,757  5.37  5.23     283       144          427
  Non-taxable                                    29,136      24,277      600      526  8.24  8.67     (26)      100           74
Federal funds sold                               65,548      99,081      910    1,159  5.58  4.74     219      (468)        (249)
                                             ----------  ----------  -------  -------              -------  --------  -----------

Total interest-earning assets                 2,575,796   2,304,390   48,755   42,215  7.61  7.43     680     5,860        6,540
                                             ----------  ----------  -------  -------              -------  --------  -----------

Noninterest-earning assets:
Cash and due from banks                         116,823     107,423
Premises and equipment                           85,135      80,269

Other, less allowance for loan losses            39,386      26,147
                                             ----------  ----------


Total noninterest-earning assets                241,344     213,839
                                             ----------  ----------

Total assets                                 $2,817,140  $2,518,229
                                             ----------  ----------

Interest-bearing liabilities:
Deposits                                      1,837,024  $1,664,059  $17,014  $14,521  3.73  3.54  $  880   $ 1,613   $    2,493
Federal funds purchased and
 securities sold under
 agreements to repurchase                       303,213     258,841    4,127    2,877  5.47  4.51     643       607        1,250
Long-term debt                                   50,963      50,000    1,050    1,031  8.24  8.25      (1)       20           19
                                             ----------  ----------  -------  -------              -------  --------  -----------


Total interest-bearing liabilities            2,191,200   1,972,900   22,191   18,429  4.07  3.79   1,522     2,240        3,762
                                             ----------  ----------  -------  -------              -------  --------  -----------

Noninterest-bearing liabilities:
Demand deposits                                 399,327     352,031
Other liabilities                                23,079      16,319


Total noninterest-bearing liabilities           422,406     368,350

Stockholders' equity                            203,534     176,979


Total liabilities and stockholders' equity   $2,817,140  $2,518,229
                                             ==========  ==========

Interest rate spread                                                                   3.54  3.64
                                                                                       ====  ====
Net interest margin                                                  $26,564  $23,786  4.15  4.19   ($842)  $ 3,620   $    2,778
                                                                     =======  =======  ====  ====  =======  ========  ===========
<FN>
(1)  Non-taxable  interest  income  has  been  adjusted  to  a taxable equivalent rate, using the federal income tax rate of 35%.
(2)  Yield/rate-volume  changes  have  been  allocated  to  each  category  based  on the percentage of each to the total change.
(3)  Nonaccrual  loans  are included in the average loan balances.  Income on such loans generally is recognized on a cash basis.
</TABLE>


                                     PAGE 8
<PAGE>
MANAGEMENT'S  DISCUSSION  AND  ANALYSIS  OF  RESULTS OF OPERATIONS AND FINANCIAL
CONDITION  (continued)
--------------------------------------------------------------------------------

Net interest income on a tax equivalent basis increased $2,778 or 11.68% for the
three  months  ended  March  31,  2000, over the comparable period in 1999.  Net
interest  margin  to  average assets declined 4 basis points from 3.83% at March
31,  1999  to 3.79% at March 31, 2000.  The decline was due to a decrease in the
ratio  of  earnings  assets  to  average assets from 91.51% at March 31, 1999 to
91.43%  at  March  31,  2000,  and  a decrease in net interest margin to average
earning  assets  from  4.19%  at  March  31,  1999  to  4.15% at March 31, 2000.

Net  interest margin to average earning assets declined by 4 basis points due to
a  10  basis  point  decline  in  the  net  interest spread.  The decline in net
interest  spread  was  offset  by  a favorable change in the contribution to net
interest  margin from the net interest position.  The net interest position as a
percent  of  earning assets increased from 14.39% at March 31, 1999 to 14.93% at
March  31,  2000.

The  decline  in  the  net  interest rate spread from 3.64% at March 31, 1999 to
3.54%  at March 31, 1999 was due to the increase in the cost of interest-bearing
liabilities  exceeding  the  increase in interest earned on earning assets.  The
cost  of  interest-bearing liabilities increased from 3.79% at March 31, 1999 to
4.07%  at  March 31, 2000, or an increase of 28 basis points, while the yield on
earning assets increased from 7.43% to 7.61%, or an increase of 18 basis points.
The  increase in the cost of interest-bearing liabilities was due to an increase
in  the  rate  paid  on deposits (primarily CDs) and repurchase agreements.  The
increase  in  the  yield  on  interest-earning  assets  was  primarily due to an
increase  in  the  yields  on  investment  securities  and  federal  funds sold.


Noninterest  income  and  expense  (Dollars  in  thousands)

Noninterest  income increased by $917 or 12.21% for the three months ended March
31, 2000, over the comparable period in 1999 due to increases in service charges
on  deposits  commissions  and fees from fiduciary activities and bankcard fees.
Service  charges  on  deposits  increased  by $980 or 23.90% over the comparable
period  primarily  due  to overall deposit growth. Additionally, commissions and
fees  from fiduciary and bankcard activities increased by $405 or 33.50%.  These
favorable  changes  were  partially  offset by a $500 or 51.65% decline in other
income.  Other income declined due to a decline in non-recurring gain on sale of
fixed  assets  and  premiums  earned  on  the  sale  of  mortgage  loans.

Noninterest  expense  increased  by  $1,418  or 6.47% for the three months ended
March  31,  2000 over the comparable period in 1999 due to increases in salaries
and  employee  benefits,  depreciation  expense,  data  processing  expense  and
bankcard  processing  expense.  Salaries and employee benefits increased $905 or
8.71%  over  the comparable period primarily due to an increase in the number of
employees,  the  addition  of  Exchange  Bank  employees  and  merit  increases.
Depreciation  expense  (included  in  net  occupancy  and furniture and fixtures
expense)  increased  by  $316  or  18.80%  over the comparable period due to the
addition  of  depreciation on Exchange Bank assets, and an increase in the level
of  assets  placed  in  service  since  March 31, 1999.  Data processing expense
increased  $151  or  8.77% over the comparable period due to the on-going growth
realized  by  Bancorporation.  Bankcard  processing expense increased by $128 or
13.72%  over  the  comparable  period  due  to  increased  bankcard  activity.

Overall, the noninterest margin (noninterest income less noninterest expense) to
average  assets  improved from a negative 2.29% for the three months ended March
31,  1999  to  a negative 2.11% for the three months ended March 31, 2000.  This
was  due  to a 17 basis point decrease in non-interest expense to average assets
and  a  1  basis  point  increase in noninterest income to average assets.  This
factor had the most measurable impact on the improvement in return on assets for
the  comparable  periods.


Income  taxes  (Dollars  in  thousands)

Total  income tax expense increased by $426 or 14.57% for the three months ended
March  31,  2000  over  the comparable period in 1999 due to the increase in net
income.  The  effective tax rate was 34.5% and 34.8% at March 31, 2000 and March
31,  1999,  respectively.


                                     PAGE 9
<PAGE>
MANAGEMENT'S  DISCUSSION  AND  ANALYSIS  OF  RESULTS OF OPERATIONS AND FINANCIAL
CONDITION  (continued)
--------------------------------------------------------------------------------
                               FINANCIAL CONDITION

Investment  securities  (Dollars  in  thousands)

As  of  March  31,  2000, the investment portfolio totaled $708,243, compared to
$625,234  at  March  31, 1999.  The investment portfolio increased as funds were
shifted from federal funds sold to the bond portfolio.  Approximately $22,000 of
investment  securities were purchased in the Exchange Bank acquisition.   During
1999,  excess  cash  was invested in federal funds sold to provide for Year 2000
liquidity.  Bancorporation  continues  to  invest  primarily  in short-term U.S.
government  obligations  to  minimize  credit, interest rate and liquidity risk.
During the first quarter, Bancorporation purchased  $40,000 of Federal Home Loan
Bank  ("FHLB") bonds.  The FHLB is a Aaa-rated government sponsored agency.  The
investment  portfolio  consisted  of  90.84%  and  91.27%  U.S.  government  and
government  agency  securities  as  of  March  31,  2000  and  March  31,  1999,
respectively.  The  remainder  of the investment portfolio consists of municipal
bonds  and  equity  securities.

Loans  and  allowance  for  loan  losses  (Dollars  in  thousands)

As  of March 31, 2000, loans totaled $1,925,368, compared to $1,598,043 at March
31,  1999.  Of  this  increase,  $95,557  was  related  to  acquisitions and the
remainder  was  the a result of normal loan growth.  The composition of the loan
portfolio  has  not shifted significantly since March 31, 1999.  Loan growth was
primarily  funded  through  core  deposits  and  short-term  borrowed  funds.

It  is  the  policy  of  Bancorporation to maintain an allowance for loan losses
which  is  adequate  to  absorb  probable losses inherent in the loan portfolio.
Management believes that the provision taken during the three months ended March
31, 2000 was appropriate to provide an allowance for loan losses which considers
the  past experience of charge-offs, the level of past due and nonaccrual loans,
the  size  and  mix  of  the  loan portfolio, credit classifications and general
economic  conditions  in  Bancorporation's  market  areas.

An  analysis  of  activity in the allowance for loan losses as of March 31, 2000
and  1999  is  presented  below.  The  allowance  for loan losses is managed and
maintained  through  charges to the provision for loan losses.  Loan charge-offs
and  recoveries  are  charged  or  credited  directly  to the allowance for loan
losses.  During  the  first  quarter  of 2000, Bancorporation recorded provision
expense  of  approximately  $586  related  to  loans  purchased  in three branch
acquisitions  based  on management's estimate of losses inherent in those loans.

<TABLE>
<CAPTION>
                                            As of and for the
                                            three months ended
                                                March 31,
                                          -----------------------
Allowance for loan losses:                   2000        1999
                                          ----------  -----------
<S>                                       <C>         <C>
Balance at beginning of period            $  32,972   $   28,306
Provision for loan losses                     1,559          663
                                          ----------  -----------
Charge-offs                                    (700)        (585)
Recoveries                                      434          376
                                          ----------  -----------
Net charge-offs                                (266)        (209)
                                          ----------  -----------
Balance at end of period                  $  34,265   $   28,760
                                          ----------  -----------
Nonperforming assets                      $   3,143   $    2,814
Annualized net charge-offs to:
Average loans                                   .06%         .05%
Loans at end of period                          .06%         .06%
Allowance for loan losses                      3.11%        2.91%
</TABLE>

Funding  sources  (Dollars  in  thousands)

Bancorporation's  primary  source  of funds is its deposit base.  Total deposits
increased  $274,445  or  13.45% from March 31, 1999 to March 31, 2000.  Deposits
totaling $158,118 were obtained through acquisitions during the period.  Average
deposits  were  $2,236,351  and $2,016,090 at March 31, 2000 and March 31, 1999,
respectively.


                                    PAGE 10
<PAGE>
MANAGEMENT'S  DISCUSSION  AND  ANALYSIS  OF  RESULTS OF OPERATIONS AND FINANCIAL
CONDITION  (continued)
--------------------------------------------------------------------------------

Short-term borrowings in the form of repurchase agreements are another source of
funds.  Short-term borrowings increased $88,244 or 37.28% from March 31, 1999 to
March  31,  2000.  Average  short-term  borrowings were $303,213 and $258,841 at
March  31,  2000  and  March  31,  1999,  respectively.

Capital  resources

Regulatory agencies define capital as Tier I, consisting of stockholders' equity
less  ineligible  intangible  assets,  and  Total  Capital, consisting of Tier I
capital  plus the allowable portion of the allowance for loan losses and certain
long-term  debt.

Regulatory  guidelines require a minimum ratio of total capital to risk-adjusted
assets  of  8  percent,  with  at least 50 percent consisting of tangible common
stockholders'  equity  and  a minimum Tier I leverage ratio of 3 percent.  Banks
which  meet  or  exceed a Tier I ratio of 6 percent, a total capital ratio of 10
percent,  and  a  Tier  I  leverage  ratio  of  5  percent  are  considered
well-capitalized  by  regulatory  standards.  The  following  table  details
Bancorporation's  capital  ratios  at  March  31,  2000  and  1999.

Capital ratios                           March 31,
                               -----------------------------
                                  2000               1999
                               ----------         ----------
Tier I leverage ratio               8.16%              8.26%
Total risk-based capital ratio     13.20%             14.37%
    Tier I                         11.96%             13.12%
    Tier II                         1.24%              1.25%

QUANTITATIVE  AND  QUALITATIVE  DISCLOSURES  ABOUT  MARKET  RISK

There  have  been  no  material changes in market risk exposures that affect the
quantitative  and  qualitative disclosures presented as part of Bancorporation's
Annual  Report  on  Form  10-K  for  the  year  ended  December  31,  1999.


                                    PAGE 11
<PAGE>
                           PART II - OTHER INFORMATION

Item  1.  Legal  Proceedings

Bancorporation  and  its  subsidiaries,  are not parties to, nor is any of their
property  the  subject of, any material or other pending legal proceeding, other
than  ordinary  routine  proceedings  incidental  to  their  business.

Item  2.  Changes  in  Securities

Not  Applicable.

Item  3.  Defaults  upon  Senior  Securities

Not  Applicable.

Item  4.  Submission  of  Matters  to  a  Vote  of  Security  Holders

Not  Applicable.

Item  5.  Other  Information

Not  Applicable.

Item  6.  Exhibits  and  Reports  on  Form  8-K

(a)     Exhibits

        11     Statement  Re  Computation  of  Earnings  Per  Share
        27     Financial  Data  Schedule

(b)     No  reports  on  Form  8-K were filed during the quarter ended March 31,
        2000


                                    PAGE 12
<PAGE>
SIGNATURES

Pursuant  to  the  requirements  of  the  Securities  Exchange  Act of 1934, the
Registrant  has  duly  caused  this  report  to  be  signed on its behalf by the
undersigned  thereunto  duly  authorized.


                                 FIRST  CITIZENS  BANCORPORATION
                                 OF  SOUTH  CAROLINA,  INC.
                                 (Registrant)


Dated:   May  11,  2000          By:  /s/  Jay  C.  Case
       -----------------              -----------------------------------------
                                      Jay C. Case, Executive Vice President
                                      (Chief  Financial  Officer)


                                    PAGE 13
<PAGE>