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        Guidance & Regulation (Food and Dietary Supplements)

Guidance Documents & Regulatory Information by Topic (Food and Dietary Supplements)

                        
                Foods Program Guidance Under Development
          Foods Program Regulations Under Development


                Acidified & Low-Acid Canned Foods Guidance Documents & Regulatory Information
          Biotechnology Guidance Documents & Regulatory Information
          Bottled Water/Carbonated Soft Drinks Guidance Documents & Regulatory Information
          Chemical, Metals, Natural Toxins & Pesticides Guidance Documents & Regulations
          Dietary Supplements Guidance Documents & Regulatory Information
          Egg Guidance, Regulation, and Other Information
          Food Allergens/Gluten-Free Guidance Documents & Regulatory Information
          Food Defense Guidance Documents & Regulatory Information
          Imports & Exports Guidance Documents & Regulatory Information
          Infant Formula Guidance Documents & Regulatory Information
          Ingredients, Additives, GRAS & Packaging Guidance Documents & Regulatory Information
          Juice Guidance Documents & Regulatory Information
          Labeling & Nutrition Guidance Documents & Regulatory Information
          Meat Guidance Documents & Regulatory Information
          Medical Foods Guidance Documents & Regulatory Information
          Milk Guidance Documents & Regulatory Information
          Produce & Plant Products Guidance Documents & Regulatory Information
          Reportable Food Registry Guidance Documents & Regulatory Information
          Retail Food Protection Guidance Documents & Regulatory Information
          Salmonella Guidance Documents & Regulatory Information
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          Seafood Guidance Documents & Regulatory Information Home
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          Guidance & Regulation (Food and Dietary Supplements)
          Guidance Documents & Regulatory Information by Topic (Food and Dietary Supplements)Guidance & Regulation (Food and Dietary Supplements) Guidance Documents & Regulatory Information by Topic (Food and Dietary Supplements)
  	
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    PrintGuidance for Industry

The documents listed below are guidance for the food industry. Guidance documents represent FDA's current thinking on a topic. They do not create or confer any rights for or on any person and do not operate to bind FDA or the public. Manufacturers can use an alternative approach if the approach satisfies the requirements of the applicable statutes and regulations.

**Related Resources:**

Cosmetics Guidance Documents
	Manual of Compliance Policy Guides - Chapter 5 Food, Colors, and Cosmetics
	Federal Register and the Code of Federal Regulations for Food and Dietary Supplements
	Foods Program Guidance Under Development
	Foods Program Regulations Under Development
	Search all FDA Guidance DocumentsIssue Date
			(YYYY/MM)
			Title
			Final/
			Draft
			Category2024/01
			Hazard Analysis and Risk-Based Preventive Controls for Human Food
			Draft
			Food Safety (FSMA)2023/12
			Menu Labeling Supplemental Guidance (Edition 2)
			Draft
			Labeling & Nutrition2023/11
			Milk and Cream Products and Yogurt Products; Final Rule to Revoke the Standards for Lowfat Yogurt and Nonfat Yogurt and To Amend the Standard for Yogurt - Small Entity Compliance Guide
			Draft
			Labeling & Nutrition2023/09
			Returning Refrigerated Transport Vehicles and Refrigerated Storage Units to Food Uses After Using Them to Preserve Human Remain
			Final
			Sanitation & Transportation2023/09
			Standards for the Growing, Harvesting, Packing, and Holding of Sprouts for Human Consumption
			Final
			Food Safety (FSMA)2023/09
			Standards for the Growing, Harvesting, Packing, and Holding of Sprouts for Human Consumption
			Draft
			Food Safety (FSMA)2023/08
			The Seafood List - FDA’s Guide to Determine Acceptable Seafood Names
			Final
			Seafood2023/07
			Temporary Policy Regarding Preventive Controls and FSVP Food Supplier Verification Onsite Audit Requirements During the COVID-19 Public Health Emergency
			Final
			Food Safety (FSMA)2023/07
			Temporary Policy Regarding Accredited Third-Party Certification Program Onsite Observation and Certificate Duration Requirements During the COVID-19 Public Health Emergency
			Final
			Food Safety (FSMA)2023/06
			Action Level for Inorganic Arsenic in Apple Juice
			Final
			Metals2023/05
			Requirements for Additional Traceability Records for Certain Foods: What You Need to Know About the FDA Regulation - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2023/04
			Transition from Temporary Policy During the COVID-19 Public Health Emergency Regarding the Qualified Exemption from the Standards for the Growing, Harvesting, Packing, and Holding of Produce for Human Consumption
			Final
			Food Safety (FSMA)2023/04
			Labeling of Certain Beers Subject to the Labeling Jurisdiction of the Food and Drug Administration
			Final
			Labeling & Nutrition2023/03
			Labeling of Infant Formula
			Final
			Infant Formula2023/03
			Questions and Answers About Dietary Guidance Statements in Food Labeling
			Draft
			Labeling & Nutrition2023/03
			Frequently Asked Questions About Medical Foods; Second Edition
			Final
			Medical Foods2023/02
			Labeling of Plant-Based Milk Alternatives and Voluntary Nutrient Statements
			Draft
			Labeling & Nutrition2023/02
			Protein Efficiency Ratio (PER) Rat Bioassay Studies to Demonstrate that a New Infant Formula Supports the Quality Factor of Sufficient Biological Quality of Protein
			Draft
			Labeling & Nutrition2023/01
			Foreign Supplier Verification Programs for Importers of Food for Humans and Animals
			Final
			Food Safety (FSMA)2023/01
			Action Levels for Lead in Food Intended for Babies and Young Children
			Draft
			Metals2022/12
			Best Practices for Convening a GRAS Panel
			Final
			Ingredients & Packaging2022/11
			Questions and Answers Regarding Food Allergen Labeling (Edition 5)
			Final
			Allergens2022/11
			Questions and Answers Regarding Food Allergen Labeling (Edition 5)
			Draft
			Allergens2022/10
			Refusal of Inspection by a Foreign Food Establishment or Foreign Government
			Final
			Food Safety (FSMA)2022/10
			Laboratory Accreditation for Analyses of Foods - What You Need to Know - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2022/09
			Prior Notice of Imported Food Questions and Answers (Edition 4)
			Final
			Food Defense2022/09
			Infant Formula Transition Plan for Exercise of Enforcement Discretion
			Final
			Infant Formula2022/08
			Policy Regarding N-acetyl-L-cysteine
			Final
			Dietary Supplements2022/08
			Questions and Answers Regarding the Final Rule, Prevention of Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation (Layers with Access to Areas Outside the Poultry House)
			Final
			Eggs2022/07
			Hazard Analysis and Risk-Based Preventive Controls for Food for Animals (#245)
			Final
			Food Safety (FSMA)2022/06
			Fish and Fishery Products Hazards and Controls Guidance; Fourth Edition
			Final
			Seafood2022/06
			Guidance for Food and Drug Administration Staff on FDA Oversight of Food Covered by Systems Recognition Arrangements
			Final
			System Recognition2022/05
			Reducing Microbial Food Safety Hazards in the Production of Seed for Sprouting
			Final
			Food Safety (FSMA)2022/05
			Infant Formula Enforcement Discretion Policy
			Final
			Infant Formula2022/04
			Evaluating the Public Health Importance of Food Allergens Other Than the Major Food Allergens Listed in the Federal Food, Drug, and Cosmetic Act
			Draft
			Allergens2022/04
			Compliance with Providing an Acceptable Unique Facility Identifier for the Foreign Supplier Verification Programs for Food Importers Regulation
			Final
			Food Safety (FSMA)2022/04
			The Accredited Third-Party Certification Program: Questions and Answers
			Draft
			Food Safety (FSMA)2022/04
			Action Levels for Lead in Juice
			Draft
			Metals2022/04
			Reconditioning of Fish and Fishery Products by Segregation
			Final
			Seafood2022/03
			Current Good Manufacturing Practice and Preventive Controls, Foreign Supplier Verification Programs, Intentional Adulteration, and Produce Safety Regulations: Enforcement Policy Regarding Certain Provisions
			Final
			Food Safety (FSMA)2022/03
			FDA's Voluntary Qualified Importer Program
			Final
			Food Safety (FSMA)2022/02
			Third-Party Certification Body Accreditation for Food Safety Audits: Model Accreditation Standards
			Final
			Food Safety (FSMA)2022/02
			Questions and Answers Regarding Channels of Trade Policy for Human Food Commodities with Chlorpyrifos Residues
			Final
			Pesticides2021/12
			Juice HACCP and the FDA Food Safety Modernization Act
			Final
			Food Safety (FSMA)2021/12
			Low-Acid Foods Packaged in Hermetically Sealed Containers (LACF) Regulation and the FDA Food Safety Modernization Act
			Final
			Food Safety (FSMA)2021/12
			Seafood HACCP and the FDA Food Safety Modernization Act
			Final
			Food Safety (FSMA)2021/11
			Temporary Permits for Interstate Shipment of Experimental Packs of Food Varying from the Requirements of Definitions and Standards of Identity
			Final
			Labeling & Nutrition2021/10
			Voluntary Sodium Reduction Goals
			Final
			Ingredients & Packaging2021/10
			Preparation of Food Contact Substance Notifications: (Toxicology Recommendations)
			Final
			Ingredients & Packaging2021/10
			Preparation of Food Contact Substance Notifications (Administrative)
			Final
			Ingredients & Packaging2021/09
			Microbiological Considerations for Antimicrobial Agents Used in Food Applications
			Final
			Food Additives2021/07
			Use of Recycled Plastics in Food Packaging (Chemistry Considerations)
			Final
			Ingredients & Packaging2021/03
			Enforcement Policy for Providing an Acceptable Unique Facility Identifier (UFI) for the 2020 Food Facility Registration Biennial Renewal Period
			Final
			Food Safety (FSMA)2020/12
			The Use of an Alternate Name for Potassium Chloride in Food Labeling
			Final
			Labeling & Nutrition2020/11
			Prior Notice of Imported Food Contingency Plan for System Outages
			Final
			Food Defense2020/11
			Voluntary Disclosure of Sesame as an Allergen
			Draft
			Labeling & Nutrition2020/10
			U.S. Agent Voluntary Identification System (VIS) for Food Facility Registration
			Final
			Food Safety (FSMA)2020/08
			The Declaration of Allulose and Calories from Allulose on Nutrition and Supplement Facts Labels
			Final
			Labeling & Nutrition2020/05
			Action Level for Inorganic Arsenic in Rice Cereals for Infants
			Final
			Metals2020/05
			Returning Refrigerated Transport Vehicles and Refrigerated Storage Units to Food Uses After Using Them to Preserve Human Remains During the COVID-19 Pandemic - Updated
			Final
			Sanitation & Transportation2020/05
			Reporting a Temporary Closure or Significantly Reduced Production by a Human Food Establishment and Requesting FDA Assistance During the COVID-19 Public Health Emergency - No longer in effect
			
			Food Safety2020/05
			Temporary Policy During the COVID-19 Public Health Emergency Regarding the Qualified Exemption from the Standards for the Growing, Harvesting, Packing, and Holding of Produce for Human Consumption - No longer in effect
			
			Food Safety (FSMA)2020/05
			Temporary Policy Regarding Certain Food Labeling Requirements During the COVID-19 Public Health Emergency: Minor Formulation Changes and Vending Machines - No longer in effect
			
			Labeling & Nutrition2020/04
			Temporary Policy Regarding Enforcement of 21 CFR Part 118 (the Egg Safety Rule) During the COVID-19 Public Health Emergency - No longer in effect
			
			Eggs2020/04
			Temporary Policy Regarding Packaging and Labeling of Shell Eggs Sold by Retail Food Establishments During the COVID-19 Public Health Emergency - No longer in effect
			
			Labeling & Nutrition2020/04
			Temporary Policy Regarding Nutrition Labeling of Standard Menu Items in Chain Restaurants and Similar Retail Food Establishments During the COVID-19 Public Health Emergency - No longer in effect
			
			Labeling & Nutrition2020/03
			Temporary Policy Regarding Nutrition Labeling of Certain Packaged Food During the COVID-19 Public Health Emergency - No longer in effect
			
			Labeling & Nutrition2020/02
			Supplemental Mitigation Strategies to Protect Food Against Intentional Adulteration
			Draft
			Food Defense2020/01
			Revision of the Nutrition and Supplement Facts Labels; Small Entity Compliance Guide
			Final
			Labeling & Nutrition2019/12
			Serving Sizes of Foods That Can Reasonably Be Consumed at One Eating Occasion, Reference Amounts Customarily Consumed, Serving Size-Related Issues, Dual-Column Labeling, and Miscellaneous Topics
			Final
			Labeling & Nutrition2019/12
			Nutrition and Supplement Facts Labels: Questions and Answers Related to the Compliance Date, Added Sugars, and Declaration of Quantitative Amounts of Vitamins and Minerals
			Final
			Labeling & Nutrition2019/08
			Policy Related to Cranberry Products with Added Flavorings
			Final
			Labeling & Nutrition2019/08
			Converting Units of Measure for Folate, Niacin, and Vitamins A, D, and E on the Nutrition and Supplement Facts Labels
			Final
			Labeling & Nutrition2019/06
			Determining the Number of Employees for Purposes of the “Small Business” Definition in Parts 117 and 507
			Final
			Food Safety (FSMA)2019/06
			Evaluating Alternate Curricula for the Standards for the Growing, Harvesting, Packing, and Holding of Produce for Human Consumption
			Draft
			Food Safety (FSMA)2019/06
			Declaration of Added Sugars on Honey, Maple Syrup, Other Single-Ingredient Sugars and Syrups, and Certain Cranberry Products
			Final
			Labeling & Nutrition2019/05
			Preparation of Food Contact Notifications for Food Contact Substances in Contact with Infant Formula and/or Human Milk
			Final
			Infant Formula2019/03
			Mitigation Strategies to Protect Food Against Intentional Adulteration
			Draft
			Food Defense2019/03
			Enforcement Policy for Entities Growing, Harvesting, Packing, or Holding Hops, Wine Grapes, Pulse Crops, and Almonds
			Final
			Food Safety (FSMA)2019/03
			Voluntary Labeling Indicating Whether Food Has or Has Not Been Derived from Genetically Engineered Atlantic Salmon
			Draft
			Labeling & Nutrition2019/03
			Voluntary Labeling Indicating Whether Foods Have or Have Not Been Derived from Genetically Engineered Plants
			Final
			Labeling & Nutrition2018/11
			Questions and Answers Regarding Mandatory Food Recalls
			Final
			Food Defense2018/11
			Establishing and Maintaining a List of U.S. Milk and Milk Product, Seafood, Infant Formula, and Formula for Young Children Manufacturers/Processors with Interest in Exporting to China
			Final
			Import & Exports2018/11
			Establishing and Maintaining a List of U.S. Dairy Product Manufacturers/Processors with Interest in Exporting to Chile
			Final
			Import & Exports2018/10
			Standards for the Growing, Harvesting, Packing, and Holding of Produce for Human Consumption
			Draft
			Food Safety (FSMA)2018/10
			Guide to Minimize Food Safety Hazards of Fresh-cut Produce
			Draft
			Food Safety (FSMA)2018/09
			Determination of Status as a Qualified Facility Under Part 117: Current Good Manufacturing Practice, Hazard Analysis, and Risk-Based Preventive Controls for Human Food AND Part 507: Current Good Manufacturing Practice, Hazard Analysis, and Risk-Based Preventive Controls for Food for Animals
			Final
			Food Safety (FSMA)2018/09
			Policy Regarding Quantitative Labeling of Dietary Supplements Containing Live Microbials
			Draft
			Dietary Supplements2018/08
			Questions and Answers Regarding Food Facility Registration (Seventh Edition)
			Final
			Food Safety (FSMA)2018/08
			Supplemental Questions and Answers Regarding Food Facility Registration
			Draft
			Food Safety (FSMA)2018/05
			Registration of Food Facilities: What You Need to Know About the FDA Regulation - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2018/05
			The FDA Food Safety Modernization Act; Extension and Clarification of Compliance Dates for Certain Provisions of Four Implementing Rules: What You Need to Know About the FDA Regulation - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2018/05
			Menu Labeling Supplemental Guidance
			Final
			Labeling & Nutrition2018/04
			Highly Concentrated Caffeine in Dietary Supplements
			Final
			Dietary Supplements2018/03
			Application of the Foreign Supplier Verification Program Regulation to the Importation of Live Animals
			Final
			Food Safety (FSMA)2018/03
			Scientific Evaluation of the Evidence on the Beneficial Physiological Effects of Isolated or Synthetic Non-Digestible Carbohydrates Submitted as a Citizen Petition (21 CFR 10.30)
			Final
			Labeling & Nutrition2018/03
			Proper Labeling of Honey and Honey Products
			Final
			Labeling & Nutrition2018/03
			Reference Amounts Customarily Consumed: List of Products for Each Product Category
			Final
			Labeling & Nutrition2018/03
			Serving Sizes of Foods That Can Reasonably Be Consumed At One Eating Occasion; Dual-Column Labeling; Updating, Modifying, and Establishing Certain Reference Amounts Customarily Consumed; Serving Size for Breath Mints; and Technical Amendments - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2018/01
			Foreign Supplier Verification Programs for Importers of Food for Humans and Animals: What You Need to Know About the FDA Regulation - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2018/01
			Application of the Foreign Supplier Verification Program Regulation to Importers of Grain Raw Agricultural Commodities
			Final
			Food Safety (FSMA)2018/01
			Considerations for Determining Whether a Measure Provides the Same Level of Public Health Protection as the Corresponding Requirement in 21 CFR part 112 or the Preventive Controls Requirements in part 117 or 507
			Draft
			Food Safety (FSMA)2018/01
			Policy Regarding Certain Entities Subject to the Current Good Manufacturing Practice and Preventive Controls, Produce Safety, and/or Foreign Supplier Verification Programs
			Final
			Food Safety (FSMA)2017/12
			Refusal of Inspection by a Foreign Food Establishment or Foreign Government
			Final
			Food Safety (FSMA)2017/11
			Sanitary Transportation of Human and Animal Food: What You Need to Know About the FDA Regulation - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2017/11
			Supply-Chain Program Requirements and Co-Manufacturer Supplier Approval and Verification for Human Food and Animal Food
			Final
			Food Safety (FSMA)2017/11
			Regulatory Framework for Substances Intended for Use in Human Food or Animal Food on the Basis of the Generally Recognized as Safe (GRAS) Provision of the Federal Food, Drug, and Cosmetic Act
			Final
			Ingredients & Packaging2017/11
			Use of the Terms “Brown King Crab” and “Golden King Crab” in the Labeling of Human Food Products
			Final
			Seafood2017/10
			Application of the “Solely Engaged” Exemptions in Parts 117 and 507
			Draft
			Food Safety (FSMA)2017/09
			Standards for the Growing, Harvesting, Packing, and Holding of Produce for Human Consumption - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2017/08
			Mitigation Strategies to Protect Food Against Intentional Adulteration - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2017/08
			Clarification on Food Establishment Waiver from Requirements of the Sanitary Transportation of Human and Animal Food Rule
			Final
			Food Safety (FSMA)2017/08
			Ultrafiltered Milk in the Production of Standardized Cheeses and Related Cheese Products
			Final
			Labeling & Nutrition2017/03
			Recognition of Acceptable Unique Facility Identifier (UFI) for the Foreign Supplier Verification Programs Regulation
			Final
			Food Safety (FSMA)2017/01
			Control of *Listeria monocytogenes* in Ready-To-Eat Foods
			Draft
			Food Safety (FSMA)2016/12
			Fruit Juice and Vegetable Juice as Color Additives in Food - WITHDRAWN
			Draft
			Juice2016/11
			Submitting Forms for Food Canning Establishment Registration and Food Process Filing to FDA in Electronic or Paper Format
			Final
			Acidified & Low-Acid Canned Foods2016/11
			What You Need to Know About Current Good Manufacturing Practice, Hazard Analysis, and Risk-Based Preventive Controls for Human Food - Small Entity Compliance Guide
			Final
			Food Safety (FSMA)2016/10
			New Dietary Ingredient Notifications and Related Issues
			Draft
			Dietary Supplements2016/10
			Frequently Asked Questions about GRAS
			Final
			Food Additives2016/10
			Describing a Hazard That Needs Control in Documents Accompanying the Food, as Required by Four Rules Implementing FSMA
			Draft
			Food Safety (FSMA)2016/09
			Necessity of the Use of Food Product Categories in Food Facility Registrations and Updates to Food Product Categories (2016 Edition)
			Final
			Food Safety (FSMA)2016/09
			Substantiation for Structure/Function Claims Made in Infant Formula Labels and Labeling
			Draft
			Infant Formula2016/09
			Use of the Term “Healthy” in the Labeling of Human Food Products
			Final
			Labeling & Nutrition2016/08
			Classification of Activities as Harvesting, Packing, Holding, or Manufacturing/Processing for Farms and Facilities
			Draft
			Food Safety (FSMA)2016/08
			Calorie Labeling of Articles of Food in Vending Machines
			Draft
			Labeling & Nutrition2016/08
			Calorie Labeling of Articles of Food in Vending Machines - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2016/07
			FDA’s Policy on Declaring Small Amounts of Nutrients and Dietary Ingredients on Nutrition Labels
			Final
			Labeling & Nutrition2016/05
			Ingredients Declared as Evaporated Cane Juice
			Final
			Labeling & Nutrition2016/05
			Labeling Guide for Restaurants and Retail Establishments Selling Away-From-Home Foods – Part II
			Final
			Labeling & Nutrition2016/04
			Exempt Infant Formula Production: Current Good Manufacturing Practices (CGMPs), Quality Control Procedures, Conduct of Audits, and Records and Reports
			Final
			Infant Formula2016/03
			Acrylamide in Foods
			Final
			Chemical Contaminants2016/02
			Alpha-Linolenic Acid, Eicosapentaenoic Acid, and Docosahexaenoic Acid Omega-3 Fatty Acids Nutrient Content Claims - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2015/11
			Questions and Answers on FDA’s Fortification Policy
			Final
			Labeling & Nutrition2015/09
			Colored Sea Salt
			Final
			Color Additives2015/07
			Questions and Answers Regarding the Final Rule, Prevention of *Salmonella* Enteritidis in Shell Eggs During Production, Storage, and Transportation
			Final
			Eggs2015/06
			Food Allergen Labeling Exemption Petitions and Notifications
			Final
			Allergens2015/03
			Nutrition Labeling of Standard Menu Items in Restaurants and Similar Retail Food Establishments - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2014/06
			Demonstration of the Quality Factor Requirements Under 21 CFR 106.96(i) for "Eligible" Infant Formulas
			Final
			Infant Formula2014/06
			Assessing the Effects of Significant Manufacturing Process Changes, Including Emerging Technologies, on the Safety and Regulatory Status of Food Ingredients and Food Contact Substances, Including Food Ingredients that are Color Additives
			Final
			Ingredients & Packaging2014/06
			Gluten-Free Labeling of Foods - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2014/04
			What You Need to Know About Establishment and Maintenance of Records - Small Entity Compliance Guide
			Final
			Food Defense2014/04
			FDA Records Access Authority Under Sections 414 and 704 of the Federal Food, Drug, & Cosmetic Act
			Final
			Food Defense2014/01
			Submitting Form FDA 2541 (Food Canning Establishment Registration) and Forms FDA 2541d, FDA 2541e, FDA 2541f, and FDA 2541g (Food Process Filing Forms) to FDA in Electronic or Paper Format - WITHDRAWN
			Draft
			Acidified & Low-Acid Canned Foods2014/01
			Dear Manufacturer Letter Regarding Changes to FDA’s Administration of Process Filings (Forms FDA 2541a and FDA 2541c) for Acidified Foods and Low-Acid Canned Foods
			Final
			Acidified & Low-Acid Canned Foods2014/01
			Distinguishing Liquid Dietary Supplements from Beverages
			Final
			Dietary Supplements2014/01
			Considerations Regarding Substances Added to Foods, Including Beverages and Dietary Supplements
			Final
			Ingredients & Packaging2013/11
			Purchasing Reef Fish Species Associated with the Hazard of Ciguatera Fish Poisoning - WITHDRAWN
			Final
			Seafood2013/09
			Questions and Answers Regarding Adverse Event Reporting and Recordkeeping for Dietary Supplements as Required by the Dietary Supplement and Nonprescription Drug Consumer Protection Act
			Final
			Dietary Supplements2013/03
			What You Need to Know About Administrative Detention of Foods - Small Entity Compliance Guide
			Final
			Food Defense2013/01
			Food Labeling Guide
			Final
			Labeling & Nutrition2012/05
			Establishing an Allowable Level for di (2-ethylhexyl)phthalate in Bottled Water - Small Entity Compliance Guide
			Final
			Bottled Water & Carbonated Soft Drinks2012/03
			Testing for *Salmonella* Species in Human Foods and Direct-Human-Contact Animal Foods
			Final
			Salmonella2012/02
			Questions and Answers Regarding Establishment and Maintenance of Records By Persons Who Manufacture, Process, Pack, Transport, Distribute, Receive, Hold, or Import Food (Edition 5)
			Final
			Food Defense2011/12
			Prevention of *Salmonella* Enteritidis in Shell Eggs During Production, Storage, and Transportation
			Final
			Eggs2011/11
			Letter to Firms that Grow, Harvest, Sort, Pack, Process, or Ship Fresh Cantaloupe
			Final
			Produce & Plant Products2011/10
			Evaluating the Safety of Flood-affected Food Crops for Human Consumption
			Final
			Produce & Plant Products2011/10
			Implementation of the Fee Provisions of Section 107 of the FDA Food Safety Modernization Act
			Final
			Food Safety (FSMA)2011/09
			Measures to Address the Risk for Contamination by *Salmonella* Species in Food Containing a Pistachio-Derived Product as an Ingredient
			Final
			Salmonella2011/08
			What You Need to Know About Prior Notice of Imported Food Shipments
			Final
			Food Defense2011/06
			Enforcement Policy Concerning Certain Prior Notice Requirements - WITHDRAWN
			Final
			Food Defense2011/04
			Questions and Answers About the Food Additive or Color Additive Petition Process
			Final
			Food Additives2011/03
			Letter to Firms that Grow, Harvest, Sort, Pack, or Ship Fresh Cilantro
			Final
			Produce & Plant Products2010/12
			Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements - Small Entity Compliance Guide
			Final
			Dietary Supplements2010/11
			Safety of Imported Traditional Pottery Intended for Use with Food and the Use of the Term “Lead Free” in the Labeling of Pottery; and Proper Identification of Ornamental and Decorative Ceramicware
			Final
			Imports & Exports2010/10
			Food Additive Petition Expedited Review
			Final
			Food Additives2010/09
			Questions and Answers Regarding Implementation of the Menu Labeling Provisions of Section 4205 of the Patient Protection and Affordable Care Act of 2010 - WITHDRAWN
			Final
			Labeling & Nutrition2010/07
			Enzyme Preparations: Recommendations for Submission of Chemical and Technological Data for Food Additive Petitions and GRAS Notices
			Final
			Food Additives2010/07
			Advisory Levels for Deoxynivalenol (DON) in Finished Wheat Products for Human Consumption and Grains and Grain By-Products used for Animal Feed
			Final
			Natural Toxins2010/06
			FDA Letter to Industry Concerning Liquid Vitamin D Dietary Supplements
			Final
			Dietary Supplements2010/05
			Use of Water by Food Manufacturers in Areas Subject to a Boil-Water Advisory
			Final
			Emergency Response2010/05
			Questions and Answers Regarding the Reportable Food Registry as Established by the Food and Drug Administration Amendments Act of 2007 (Edition 2)
			Draft
			Reportable Food Registry2010/04
			Prevention of *Salmonella* Enteritidis in Shell Eggs During Production, Transportation, and Storage - Small Entity Compliance Guide
			Final
			Salmonella2010/04
			Sanitary Transportation of Food
			Final
			Sanitation & Transportation2010/03
			Bottled Water and Total Coliform and *E. coli* - Small Entity Compliance Guide
			Final
			Bottled Water & Carbonated Soft Drinks2010/03
			Providing Regulatory Submissions in Electronic or Paper Format to the Office of Food Additive Safety
			Draft
			Ingredients & Packaging2010/03
			Submitting a Report for Multiple Facilities to the Reportable Food Electronic Portal as Established by the Food and Drug Administration Amendments Act of 2007
			Final
			Reportable Food Registry2009/10
			Letter Regarding Point of Purchase Food Labeling
			Final
			Labeling & Nutrition2009/09
			Questions and Answers Regarding the Labeling of Dietary Supplements as Required by the Dietary Supplement and Nonprescription Drug Consumer Protection Act
			Final
			Dietary Supplements2009/09
			Questions and Answers Regarding the Reportable Food Registry as Established by the Food and Drug Administration Amendments Act of 2007
			Final
			Reportable Food Registry2009/07
			Color Additive Petitions - FDA Recommendations for Submission of Chemical and Technological Data on Color Additives for Food, Drugs, Cosmetics, or Medical Devices
			Final
			Color Additives2009/07
			Draft Guide to Minimize Microbial Food Safety Hazards of Leafy Greens - WITHDRAWN
			Draft
			Produce & Plant Products2009/07
			Draft Guide to Minimize Microbial Food Safety Hazards of Melons - WITHDRAWN
			Draft
			Produce & Plant Products2009/07
			Draft Guide to Minimize Microbial Food Safety Hazards of Tomatoes - WITHDRAWN
			Draft
			Produce & Plant Products2009/06
			Questions and Answers Regarding Adverse Event Reporting and Recordkeeping for Dietary Supplements as Required by the Dietary Supplement and Nonprescription Drug Consumer Protection Act
			Final
			Dietary Supplements2009/06
			Bottled Water and Residual Disinfectants and Disinfection Byproducts - Small Entity Compliance Guide
			Final
			Metals2009/06
			Measures to Address the Risk for Contamination by *Salmonella* Species in Food Containing a Pistachio-Derived Product As An Ingredient
			Draft
			Produce & Plant Products2009/05
			CPG Sec 110.310 Prior Notice of Imported Food Under the Public Health Security and Bioterrorism Preparedness and Response Act of 2002 - Compliance Policy Guide
			Final
			Food Defense2009/05
			Health Claims on Calcium and Osteoporosis; and Calcium, Vitamin D, and Osteoporosis - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2009/04
			Cochineal Extract and Carmine: Declaration by Name on the Label of All Foods and Cosmetic Products That Contain These Color Additives - Small Entity Compliance Guide
			Final
			Color Additives2009/04
			Bottled Water and Arsenic - Small Entity Compliance Guide
			Final
			Metals2009/04
			Bottled Water and Uranium - Small Entity Compliance Guide
			Final
			Metals2009/03
			Recommendations for Submission of Chemical and Technological Data for Direct Food Additive Petitions
			Final
			Food Additives2009/03
			Measures to Address the Risk for Contamination by *Salmonella* Species in Food Containing a Peanut-Derived Product as an Ingredient
			Final
			Produce & Plant Products2009/02
			Referral Program from the Food and Drug Administration to the National Oceanic and Atmospheric Administration Seafood Inspection Program for the Certification of Fish and Fishery Products for Export to the European Union and the European Free Trade Association
			Final
			Seafood2009/02
			1991 Letter to Seafood Manufacturers Regarding the Fraudulent Practice of Including Glaze (ice) as Part of the Weight of Frozen Seafood
			Final
			Seafood2009/01
			Substantiation for Dietary Supplement Claims Made Under Section 403(r) (6) of the Federal Food, Drug, and Cosmetic Act
			Final
			Dietary Supplements2009/01
			Evidence-Based Review System for the Scientific Evaluation of Health Claims
			Final
			Labeling & Nutrition2008/12
			Dear Manufacturer Letter Regarding Front-of-Package Symbols
			Final
			Labeling & Nutrition2008/07
			Final Rule Declaring Dietary Supplements Containing Ephedrine Alkaloids Adulterated Because They Present an Unreasonable Risk - Small Entity Compliance Guide
			Final
			Dietary Supplements2008/07
			Standard of Identity for White Chocolate - Small Entity Compliance Guide
			Final
			Food Standards2008/07
			Nutrient Content Claims Definition for “High Potency” and Definition for “Antioxidant” for Use in Nutrient Content Claims for Dietary Supplements and Conventional Foods - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2008/04
			Labeling Guide for Restaurants and Retail Establishments Selling Away-From-Home Foods - Part I
			Final
			Labeling & Nutrition2008/02
			Guide to Minimize Microbial Food Safety Hazards of Fresh-cut Fruits and Vegetables
			Final
			Produce & Plant Products2008/01
			Draft Guidance and Protocol for Industry and Food and Drug Administration Staff on Certification of Fish and Fishery Products for Export to the European Union and European Free Trade Association - WITHDRAWN
			Draft
			Seafood2007/12
			Preparation of Food Contact Notifications and Food Additive Petitions for Food Contact Substances (Chemistry Recommendations)
			Final
			Food Additives2007/10
			Cosmetics Processors and Transporters: Cosmetics Security Preventive Measures Guidance - WITHDRAWN
			Final
			Food Defense2007/10
			Food Security Preventive Measures Guidance for Dairy Farms, Bulk Milk Transporters, Bulk Milk Transfer Stations and Fluid Milk Processors
			Final
			Food Defense2007/10
			Food Security Preventive Measures Guidance for Retail Food Stores and Food Service Establishments
			Final
			Food Defense2007/09
			Dear Manufacturer Letter Regarding Sugar Free Claims
			Final
			Labeling & Nutrition2007/07
			Redbook 2000: Toxicological Principles for the Safety Assessment of Food Ingredients
			Final
			Food Additives2007/06
			Refrigerated Carrot Juice and Other Refrigerated Low-Acid Juices
			Final
			Juice2007/05
			Small Business Nutrition Labeling Exemption
			Final
			Labeling & Nutrition2007/02
			Letter to Industry, State and Local Food Regulators and Inspectors Regarding Web-based ALERT Training
			Final
			Food Defense2007/01
			Dear Manufacturer Letter Regarding Food Labeling
			Final
			Labeling & Nutrition2006/11
			Lead in Candy Likely To Be Consumed Frequently by Small Children: Recommended Maximum Level and Enforcement Policy
			Final
			Chemical Contaminants2006/08
			Estimating Dietary Intake of Substances in Food
			Final
			Food Additives2006/06
			Recommendations for the Early Food Safety Evaluation of New Non-Pesticidal Proteins Produced by New Plant Varieties Intended for Food Use
			Final
			Biotechnology2006/06
			Summary Table of Recommended Toxicological Testing for Additives Used in Food
			Final
			Food Additives2006/05
			Preparing a Claim of Categorical Exclusion or an Environmental Assessment for Submission to CFSAN
			Final
			Food Additives2006/05
			FDA's Implementation of Qualified Health Claims
			Final
			Labeling & Nutrition2006/04
			Guidance on the Labeling of Certain Uses of Lecithin Derived from Soy Under Section 403(w) of the Federal Food, Drug, and Cosmetic Act - WITHDRAWN
			Final
			Labeling & Nutrition2006/03
			Frequently Asked Questions about FDA's Regulation of Infant Formula
			Final
			Infant Formula2006/02
			Whole Grain Label Statements
			Draft
			Labeling & Nutrition2005/11
			Notice to Growers, Food Manufacturers, Food Warehouse Managers, and Transporters of Food Products on Decontamination of Transport Vehicles
			Final
			Food Defense2005/11
			Guidance for Records Access Authority Provided in Title III, Subtitle A, of the Public Health Security and Bioterrorism Preparedness and Response Act of 2002
			Final
			Food Defense2005/09
			Letter to State Regulatory Agencies and Firms That Produce Treated (but not Pasteurized) and Untreated Juice and Cider
			Final
			Juice2005/05
			Channels of Trade Policy for Commodities With Residues of Pesticide Chemicals, for Which Tolerances Have Been Revoked, Suspended, or Modified by the Environmental Protection Agency Pursuant to Dietary Risk Considerations
			Final
			Pesticides2005/04
			Dietary Supplement Labeling Guide
			Final
			Dietary Supplements2005/04
			Pre-Petition Consultations for Food Additives and Color Additives
			Final
			Food Additives2005/04
			Templates for Reporting Toxicology Data
			Final
			Food Additives2005/04
			Submitting Requests under 21 CFR 170.39 Threshold of Regulation for Substances Used in Food-Contact Articles
			Final
			Food Additives2005/04
			Entry Types and Entry Identifiers - Prior Notice of Imported Food - WITHDRAWN
			Final
			Food Defense2004/10
			Recommendations to Processors of Apple Juice or Cider on the Use of Ozone for Pathogen Reduction Purposes
			Final
			Juice2004/03
			Juice Hazard Analysis Critical Control Point Hazards and Controls Guidance, First Edition
			Final
			Juice2003/10
			Label Warning Statements for Iron-Containing Supplements and Drugs - Small Entity Compliance Guide
			Final
			Dietary Supplements2003/09
			Questions and Answers on Juice HACCP Regulation (2003)
			Final
			Juice2003/08
			Trans Fatty Acids in Nutrition Labeling, Nutrient Content Claims, and Health Claims - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2003/07
			Interim Procedures for Qualified Health Claims in the Labeling of Conventional Human Food and Human Dietary Supplements
			Final
			Labeling & Nutrition2003/06
			Standardized Training Curriculum for Application of HACCP Principles to Juice Processing
			Final
			Juice2003/04
			Bulk Transport of Juice Concentrates and Certain Shelf-Stable Juices
			Final
			Juice2003/04
			Juice HACCP - Small Entity Compliance Guide
			Final
			Juice2002/12
			Implementation of Section 403(t) of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 343(t)) Regarding the Use of the Term "Catfish"
			Final
			Seafood2002/11
			Regulatory Procedures Manual Chapter 9 Subchapter on Recommending Customs' Seizure and Destruction of Imported Human and Animal Food That Has Not Been Reconditioned
			Draft
			Imports & Exports2002/10
			Exemptions from the Warning Label Requirement for Juice
			Final
			Juice2002/10
			Implementation of Section 10809 of the Farm Security and Investment Act of 2002 Regarding the Petition Process to Request Approval of Labeling for Foods that Have Been Treated with Irradiation
			Final
			Labeling & Nutrition2002/10
			Guidance for Small Businesses: Submission of Comments for CFSAN Rulemaking
			Final
			Small Business2002/06
			Channels of Trade Policy for Commodities with Vinclozolin Residues
			Final
			Pesticides2002/01
			Structure/Function Claims - Small Entity Compliance Guide
			Final
			Dietary Supplements2001/11
			Fumonisin Levels in Human Foods and Animal Feeds
			Final
			Natural Toxins2001/09
			Questions and Answers on Juice HACCP Regulation
			Final
			Juice2001/07
			Safe Handling Statements on Labeling of Shell Eggs and the Refrigeration of Shell Eggs Held for Retail Distribution - Small Entity Compliance Guide
			Final
			Eggs2001/07
			Serving Sizes Reference Amount for Baking Powder, Baking Soda, Pectin - Small Entity Compliance Guide
			Final
			Labeling & Nutrition2001/07
			Refusal of Inspection or Access to HACCP Records Pertaining to the Safe and Sanitary Processing of Fish and Fishery Products
			Final
			Seafood2001/01
			The FDA Importer's Guide Low-Acid Canned & Acidified Foods - WITHDRAWN
			Final
			Acidified & Low-Acid Canned Foods2000/12
			Channels of Trade Policy for Commodities with Methyl Parathion Residues
			Final
			Pesticides2000/08
			Action Levels for Poisonous or Deleterious Substances in Human Food and Animal Feed
			Final
			Contaminates1999/12
			Significant Scientific Agreement in the Review of Health Claims for Conventional Foods and Dietary Supplements - WITHDRAWN
			Final
			Labeling & Nutrition1999/12
			Seafood HACCP Transition Guidance
			Final
			Seafood1999/10
			Reducing Microbial Food Safety Hazards For Sprouted Seeds - WITHDRAWN
			Final
			Produce & Plant Products1999/10
			Sampling And Microbial Testing Of Spent Irrigation Water During Sprout Production - WITHDRAWN
			Final
			Produce & Plant Products1999/07
			Antimicrobial Food Additives
			Final
			Food Additives1999/01
			Statement of Identity, Nutrition Labeling, and Ingredient Labeling of Dietary Supplements - Small Entity Compliance Guide
			Final
			Dietary Supplements1999/01
			Questions and Answers on HACCP Regulation for Fish and Fishery Products
			Final
			Seafood1998/10
			Guide to Minimize Microbial Food Safety Hazards for Fresh Fruits and Vegetables
			Final
			Produce & Plant Products1998/09
			Use of Antibiotic Resistance Marker Genes in Transgenic Plants - WITHDRAWN
			Draft
			Biotechnology1998/06
			Notification of a Health Claim or Nutrient Content Claim Based on an Authoritative Statement of a Scientific Body
			Final
			Labeling & Nutrition1998/05
			Food Defect Levels Handbook
			Final
			Sanitation & Transportation1998/03
			Guide for Developing and Using Data Bases for Nutrition Labeling
			Final
			Labeling & Nutrition1997/10
			Consultation Procedures under FDA's 1992 Statement of Policy for Foods Derived from New Plant Varieties
			Final
			Biotechnology1997/09
			Sourcing and Processing of Gelatin to Reduce the Potential Risk Posed by Bovine Spongiform Encephalopathy (BSE) in FDA-Regulated Products for Human Use - WITHDRAWN
			Final
			Food Additives1997/02
			Labeling of Foods that Need Refrigeration by Consumers
			Final
			Labeling & Nutrition1996/06
			Label Declaration of Allergenic Substances in Foods; Notice to Manufacturers
			Final
			Labeling & Nutrition1995/06
			Letter to Manufacturers, Importers, and Distributors of Imported Candy and Candy Wrappers
			Final
			Lead1993/10
			Guidelines for Determining Metric Equivalents of Household Measures
			Final
			Labeling & Nutrition
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                                                                                  Content current as of:
      01/30/2024
                  
                   
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