Skip to main content
          Skip to FDA Search
          Skip to in this section menu
          Skip to footer links


U.S. flagAn official website of the United States government

					Here’s how you know
          			Dot gov**The .gov means it’s official.**Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
							      SSL**The site is secure.** The **https://** ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. 
			U.S. Food and Drug Administration
				
        Search
            Menu
							
						Search FDA
									
									Submit search 
		Featured
							Contact FDA
	                FDA Guidance Documents
	                Recalls, Market Withdrawals and Safety Alerts
	                Press Announcements
	                Warning Letters
	                Advisory Committees
	                En Español

					Products
            Food
							Drugs
							Medical Devices
							Radiation-Emitting Products
							Vaccines, Blood, and Biologics
							Animal and Veterinary
							Cosmetics
							Tobacco ProductsTopics
            About FDA
							Combination Products
							Regulatory Information
							Safety
							Emergency Preparedness
							International Programs
							News and Events
							Training and Continuing Education
							Inspections and Compliance
							Science and ResearchInformation For
            Consumers
	            Patients
	            Industry
	            Health Professionals
	            Federal, State and Local Officials 
 In this section:

        Packaging & Food Contact Substances (FCS)

Inventory of Food Contact Substances Listed in 21 CFR Home
          Food
          Food Ingredients & Packaging
          Packaging & Food Contact Substances (FCS)
          Inventory of Food Contact Substances Listed in 21 CFRPackaging & Food Contact Substances (FCS) Inventory of Food Contact Substances Listed in 21 CFR
  	
        Share
    Post
    Linkedin

    Email
    PrintThis database contains an inventory of substances authorized in Title 21 of the U.S. Code of Federal Regulations (21 CFR) for uses in contact with foods. The database contains information on the substance identity and listed FDA regulations for the specific intended uses and use conditions authorized. The listing  includes Food Contact Substances (FCSs) including indirect food additives listed under 21 CFR Parts 175-178, 179.45, and 180.22 as well as secondary direct additives listed in 21 CFR 173, prior-sanctioned food ingredients listed in 21 CFR 181, and substances affirmed as generally recognized as safe listed in 21 CFR 186. 1

The inventory also contains information on substances listed in 21 CFR 189 that are prohibited from use as food contact substances.

In addition to ingredients authorized and listed in 21 CFR, FDA maintains separate inventories for premarket authorizations for food contact substances issued under the Food Contact Substance Notification (FCN) and Threshold of Regulation Exemptions (TOR) programs.

For further details to help determine the regulatory status of substances used in food contact applications, visit “Determining the Regulatory Status of Components of a Food Contact Material.”

Launch the Database

1 The inventory does not include substances affirmed as generally recognized as safe for direct addition to food listed in 21 CFR 184. These are listed in the Substances Added to Food (formerly EAFUS) database.

                                                                                  Content current as of:
      04/16/2021
                  
                   
Regulated Product(s)
		 Food & BeveragesTopic(s)
			  Food Contact Substances (FCS)Inventory of Food Contact Substances Listed in 21 CFR
 
 Footer Links
    FDA Archive
          About FDA
          Accessibility
      Visitor Information
          Website Policies / Privacy
          No FEAR Act
          Vulnerability Disclosure Policy
      FOIA
          HHS.gov
          USA.gov
    Contact FDA
      Follow FDA on Facebook
      Follow FDA on X
      Follow FDA on Instagram
      Follow FDA on LinkedIn
      View FDA videos on YouTube
      Subscribe to FDA RSS feeds
    FDA Homepage
    Contact Number
      1-888-INFO-FDA (1-888-463-6332) Back toTop