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                                                                   EXHIBIT 10.14

                    MASTER RESEARCH AND DEVELOPMENT AGREEMENT

This Agreement is made effective this first day of May, 2001 by and between
Temple University - Of The Commonwealth System of Higher Education, having a
principal place of business at Broad Street and Montgomery Avenue, Philadelphia,
Pennsylvania (hereinafter referred to as "Temple") and Nutraceutix, Inc., having
a principal place of business at 8340 154th Avenue NE Redmond, Washington
98052-3864(hereinafter referred to as "Company").

WHEREAS, the parties have entered into a License Agreement effective September
6, 2000 (hereinafter referred to as the "License") pertaining to Temple's U.S.
Patent Number 6,090,411 issued July, 18, 2000;

WHEREAS, Company wishes that Temple perform certain testing and/or research of
interest to Company in connection with the development of dietary supplement,
over-the-counter or prescription products, and wishes to obtain the results of
the aforementioned testing and/or research; and

WHEREAS, Temple wishes to undertake the aforementioned testing and/or research
and to publish the results thereof without jeopardizing the confidentiality of
Company's confidential information;

NOW, THEREFORE, in consideration of the premises and of the covenants and
obligations hereinafter set forth, the parties, intending to be legally bound,
agree as follows:

                             ARTICLE I - DEFINITIONS

1.1  "Project" shall mean an individual testing and/or research project under
     this Agreement, the scope, duration and additional costs of which are
     described in an exhibit that is attached to this Agreement by mutual
     written consent of the parties.

1.2  "Project Period" shall mean the period of performance of a Project, which
     shall terminate on the earlier of (i) the date specified in the
     corresponding exhibit to this Agreement or (ii) the date on which Company
     notifies Temple in writing that it accepts the Project Results therefor.

1.3  "Project Cost" shall mean the amount of money, if any, to be paid by
     Company to Temple to carry out each Project, as specified in the
     corresponding exhibit to this Agreement.

1.4  "Project Results" shall mean discoveries, inventions, know-how, testing
     data, methods, techniques and other information, patentable or
     unpatentable, resulting from Company's funding of any Project during the
     term of this Agreement.

1.5  "Patentable Results" shall mean Project Results that Temple deems, in its
     sole discretion, to be patentable and for which Temple files a United
     States patent application within six (6) months of the end of the
     corresponding Project Period.

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1.6  "Improvement Patents" shall mean United States patent applications filed by
     Temple for Patentable Results covered by at least one claim of a patent
     application or patent previously under the License, and any foreign
     counterparts thereof, or any continuations, continuations-in-part,
     divisions, re-issues, additions, renewals or extensions thereof, and any
     patents issuing therefrom.

1.7  "New Patents" shall mean United States patent applications filed by Temple
     for Patentable Results not covered by any claim of a patent application or
     patent previously under the License, and any foreign counterparts thereof,
     or any continuations, continuations-in-part, divisions, re-issues,
     additions, renewals or extensions thereof, and any patents issuing
     therefrom.

1.8  "Principal Investigator" shall mean Dr. Reza Fassihi, designated by Temple
     to direct the Projects and to serve as the contact person for Company on
     all technical matters relating to the Projects.

1.9  "Confidential Information" shall mean all information disclosed and any
     tangible property pertaining thereto supplied by one party to the other.
     Any information disclosed in writing shall be deemed Confidential
     Information only if marked "Confidential." Any information disclosed orally
     shall be deemed Confidential Information only if reduced to writing and a
     copy marked "Confidential" is provided to the receiving party within thirty
     (30) days of the date of oral disclosure. However, Confidential Information
     shall not include information that: (i) was known to the receiving party
     prior to the date of the disclosure by the other party; or (ii) is lawfully
     received in good faith at any time by the receiving party from a third
     party lawfully in possession of the same and having the right to disclose
     the same; or (iii) is, as of the date of receipt, in the public domain or
     subsequently enters the public domain other than by reason of acts or
     omissions of receiving party; or (iv) the receiving party is required to
     disclose by law, rule of court or regulation; or (v) is independently
     developed by the receiving party, as evidenced by written records.

                               ARTICLE II - SCOPE

2.1  This Agreement pertains to the development of dietary supplement,
     over-the-counter and prescription products. The scope of the work to be
     performed under each Project shall be described in an exhibit in the form
     attached hereto as Exhibit A that, by mutually written consent, shall be
     attached hereto and incorporated herein by reference, such exhibit to
     specify, for each Project, the scope of the work to be performed, the
     Project Costs, if any, and the Project Period.

2.2  Temple shall make reasonable efforts to complete each Project. However,
     Temple makes no warranties as to the completion of any Project or the
     achievement of any particular goal.

                             ARTICLE III - PAYMENTS

3.1  Company shall pay to Temple the Project Cost for each Project as specified
     in the applicable version of Exhibit A to this Agreement. Unless otherwise
     specified on such document, said

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     Project Cost shall be paid in two equal non-refundable payments, the first
     due within thirty (30) days of the start of the Project and the second due
     within thirty (30) days of receipt by Company of Temple's report on Project
     Results for such Project pursuant to Paragraph 4.5 of this Agreement.
     Checks shall be made to "Temple University" (with the name of the Principal
     Investigator shown for reference purposes) and sent to the attention of
     "Business Manager" at the address shown in Paragraph 8.5 of this Agreement.

                      ARTICLE IV - TRANSFER OF INFORMATION

4.1  During the "Confidentiality Period" described at the end of this Paragraph
     4.1, the receiving party shall hold Confidential Information disclosed by
     the other party in strict confidence; shall not use such Confidential
     Information except as permitted herein; and shall not disclose, directly or
     indirectly, such Confidential Information to any third party without the
     prior written consent of the disclosing party. The receiving party shall
     use at least the same degree of care to maintain the other party's
     Confidential Information secret as it uses in maintaining as secret its own
     confidential information, but always at least a reasonable degree of care.
     The receiving party shall restrict disclosure of the other party's
     Confidential Information solely to those of the employees of the receiving
     party having a need to know such Confidential Information in order to
     accomplish the purpose set forth herein. The receiving party shall also
     advise its employees before they have access to the other party's
     Confidential Information, of the obligations of the receiving party
     hereunder, and require such employees to maintain those obligations. For
     purposes of this Paragraph 4.1, the Confidentiality Period shall be a
     period of five (5) years from the date of disclosure of the Confidential
     Information, provided that if the disclosing party notifies the receiving
     party in writing prior to the end of that five (5) year period that it
     wishes to extend the Confidentiality Period with respect to a particular
     item or items of Confidential Information, the Confidentiality Period with
     respect to the item(s) of Confidential Information so identified shall be
     extended until the date specified by the disclosing party in its written
     notification.

4.2  Upon request by the disclosing party, the other party shall promptly return
     all written materials or samples of tangible property received hereunder,
     with the exception that one copy of written materials may be retained by
     the other party solely for archival purposes. In the alternative, upon the
     disclosing party's request, the other party shall return or destroy all
     materials and confirm such destruction in writing.

4.3  Temple shall provide to Company a copy of any proposed publication or other
     disclosure, written or oral, containing Project Results, at least sixty
     (60) days before the date of submission of such proposed publication or
     other disclosure, for comment by Company. During the aforementioned sixty
     (60) day period, Company may request in writing that its Confidential
     Information be removed from the proposed publication or other disclosure,
     and Temple agrees to comply. Further, (i) if the proposed publication or
     other disclosure concerns Project Results owned by Company pursuant to
     Paragraph 5.1, Temple shall remove from the proposed publication or other
     disclosure such information concerning the Project Results as Company may
     specify during such sixty (60) day period, and (ii) if the proposed
     publication or other disclosure concerns Project Results owned by Temple
     pursuant to Paragraph 5.2 and Company requests, during said sixty (60) day
     period, that Temple file a

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     patent application with respect to the subject Project Results, Temple
     shall file a patent application with respect to the subject Project Results
     prior to making the proposed publication or other disclosure.

4.4  The Principal Investigator shall submit to Company a report on Project
     Results within thirty (30) days of the end of the corresponding Project
     Period.

                          ARTICLE V - OWNERSHIP RIGHTS

5.1  Subject to the provisions of Paragraph 4.3 of this Agreement, title to
     Project Results other than Patentable Results shall belong exclusively to
     Company. Temple shall not disclose Project Results owned by Company to any
     third party without Company's prior written consent. The foregoing
     prohibition on disclosure applies to oral disclosures as well as disclosure
     in written or computer-readable form or through utilization of technology.

5.2  Title to Patentable Results shall belong exclusively to Temple and Temple
     shall have the exclusive right to procure patents therefor provided that if
     Temple fails to file a patent application for any such Patentable Result
     within six (6) months after the end of the applicable Project Period, title
     to such Patentable Result shall thereafter belong exclusively to Company.
     In the event Temple files such a patent application, Temple shall so notify
     Company in writing within thirty (30) days of the filing date.

                     ARTICLE VI - LICENSE AND OPTION RIGHTS

6.1  Company shall have the option to add to the License any Improvement Patent
     that is not already under the License provided that such option is
     exercised in writing within thirty (30) days of receipt by Company of
     Temple's notice pursuant to Paragraph 5.2. Company shall make the royalty
     payments specified in Paragraphs 4.1 and 4.3 of the License with respect to
     any Improvement Patent added to the License pursuant to this Paragraph 6.1,
     but shall not be required to pay the license fee specified in Paragraph 4.2
     of the License with respect to any Improvement Patent.

6.2  Company shall have the option to add to the License any New Patent that is
     not already under the License provided that such option is exercised in
     writing within three (3) months of the end of the Project. Company shall
     make the royalty payments specified in Paragraphs 4.1 and 4.3 of the
     License with respect to any New Patent added to the License pursuant to
     this Paragraph 6.2. In addition, Company shall pay, as specified in
     Paragraph 4.2 of the License, a non-refundable license fee of [*] for each
     New Patent added to the License, and the payment shall not be creditable
     against any other payments due to Temple under the License.

6.3  In further consideration of Temple's work on Projects, any product making
     use of Project Results owned by Company pursuant to Article 5 of this
     Agreement, notwithstanding any provisions to the contrary in Paragraph 1.10
     and in Article 4 of the License, shall be considered LICENSED PRODUCT under
     the License and shall be subject to royalties payable to Temple at [*] of
     the rate provided in Paragraphs 4.1 and 4.3 of the

*Certain information on this page has been omitted and filed separately with the
Commission. Confidential treatment has been requested with respect to the
omitted portions.

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     License, with a royalty payment period of ten (10) years from the date of
     FIRST SALE of such LICENSED PRODUCT.

6.4  Temple shall have an irrevocable, non-exclusive license to practice,
     royalty-free, all Project Results owned by Company for Temple's own
     internal, non-commercial educational and research purposes.

6.5  Company shall be responsible, pursuant to Paragraph 7.1 of the License, for
     all costs and expenses incurred by Temple on account of any patent
     application or patent that is added to the License, which costs and
     expenses are incurred both before and after the date such patent
     application or patent is added to the License. However, if Company wishes
     to add a Patentable Result to LICENSED PRODUCTS under the License but
     believes that obtaining a patent for such Patentable Result is not
     economically justified in light of all relevant business considerations,
     Company may so notify Temple in writing within thirty (30) days of receipt
     by Company of Temple's notice, pursuant to Paragraph 5.2. In the event of
     such notice by Company to Temple, notwithstanding any provisions to the
     contrary in Paragraphs 1.10 and in Article 4 of the License, any product
     derived from such Patentable Result shall be considered LICENSED PRODUCT
     under the License as of the effective date of Company's notice, except that
     for such LICENSED PRODUCT: (i) Company's licensing rights shall be
     non-exclusive, (ii) royalties shall be at one-half (1/2) of the rate
     provided in Paragraph 4.1 of the License, (iii) the royalty payment period
     shall be ten (10) years from the date of FIRST SALE of such LICENSED
     PRODUCT, and (iv) Company shall not be required to pay any patent costs or
     license fees for such patent application, its foreign counterparts, or any
     patents issuing therefrom.

                       ARTICLE VII - TERM AND TERMINATION

7.1  The initial term of this Agreement shall begin on the effective date of
     this Agreement and, unless extended or renewed in writing by both parties,
     shall end on the later of (i) twenty four (24) months from the effective
     date of this Agreement or (ii) the end of any Project Period then in
     effect.

7.2  The terms and conditions of Articles IV, V and VI herein shall survive
     termination of this Agreement.

                          ARTICLE VIII - MISCELLANEOUS

8.1  This Agreement constitutes the entire understanding of the parties with
     respect to the matters herein contained and each acknowledges and agrees
     that, except for the License, there are no warranties, representations or
     understandings between them other than those expressly set forth herein.
     Each party warrants and represents that the terms of this Agreement are not
     inconsistent with any other contractual or legal obligations it may have.
     This Agreement may be modified only by written consent signed by both
     parties.

8.2  The rights and duties of the parties shall be governed by the laws of the
     Commonwealth of Pennsylvania. The parties agree that any dispute arising
     out of this Agreement may be

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     resolved by recourse to the courts of the Commonwealth of Pennsylvania or
     the United States District Court for the Eastern District of Pennsylvania.

8.3  If any arbitration, litigation or other legal proceedings relating to this
     Agreement occurs, the prevailing party shall be entitled to recover from
     the other party (in addition to any other relief awarded or granted) its
     reasonable costs and expenses, including attorney's fees, incurred in the
     proceedings.

8.4  This Agreement is binding upon the parties, and upon the directors,
     officers, employees and agents of each.

8.5  Any notice, report, or other communication required hereunder shall be sent
     to the parties at the addresses below:

         To Temple:           Office of Technology Transfer
                              Temple University (083-45)
                              1601 N. Broad Street, Room 406
                              Philadelphia, PA 19122-6099

           To Company:        Nutraceutix, Inc.
                              Attention: David T. Howard
                              8340 154th Avenue NE
                              Redmond, Washington 98052-3864

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IN WITNESS WHEREOF, the parties have caused this Agreement to be executed by
their duly authorized representatives the day and year written below.

Temple University - Of The Commonwealth System Of Higher Education:

By: /s/                                                Date:____________
    ----------------------------------------
        Martin S. Dorph
        Vice President, Chief Financial Officer and Treasurer

Nutraceutix, Inc.:

By: /s/
    ----------------------------------------           Date:____________
        David T. Howard
        President & CEO

IN ACKNOWLEDGMENT OF HAVING READ UNDERSTOOD THE FOREGOING:

By: /s/
    ----------------------------------------           Date:____________
        Principal Investigator

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