UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
 Washington, D.C. 20549
 FORM 10-K/A
(Amendment No. 1)
  þ
    
    ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 For the fiscal year ended December 31, 2010
 OR
 o
    
    TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 For
the transition period from
 to
 Commission file number 000-23661
 ROCKWELL MEDICAL TECHNOLOGIES, INC.
  Michigan
    
    38-3317208(State or other jurisdiction of 
incorporation or organization)
    
    (I.R.S. Employer
Identification No.)30142 Wixom Road 
Wixom, Michigan
    
    48393(Address of principal executive offices)
    
    (Zip Code)
 (Registrants telephone number, including area code)
  Title of Each Class:
    
    Name of each exchange on which registered:Common Stock, no par value
    
    Nasdaq Global Market
    o þ
 o þ
 þ o
 o o
 o
  Large accelerated filer o
    
    Accelerated filer þ
    
    Non-accelerated filer o
    
    Smaller reporting company o(Do not check if a smaller reporting company)
 o þ
   Documents Incorporated by Reference




---



##### 



Explanatory Note
   Item 15. Exhibits, Financial Statement Schedules.
 (a)
 (b) Exhibits
  3.1
    
    Amended and Restated Articles of Incorporation, dated as of June
4, 2008 (Companys Form 10-Q filed August 12, 2008).3.2
    
    Amended and Restated Bylaws (Companys Form 8-K filed November
25, 2008).4.1
    
    Form of Warrant (Companys Form 8-K filed December 4, 2007).4.2
    
    RJ Aubrey Warrant Agreement, dated November 28, 2007 (Companys
Form 8-K filed December 4, 2007).4.3
    
    Form of Investor Warrant to Purchase Common Stock issuable by
the Company to the investor signatories to the Subscription Agreement, filed as
exhibit F to the Placement Agency Agreement (Companys Form 8-K filed September
30, 2009).4.4
    
    Form of Placement Agent Warrant issuable by the Company to JMP
Securities LLC and Wedbush Securities Inc. (Companys Form 8-K filed September
30, 2009).4.5
    
    Warrant issued to RJ Aubrey IR Services LLC as of September 30,
2008 (Companys Form S-3 (file no. 333-160710)).4.6
    
    Warrant issued to Lions Gate Capital as of October 3, 2007
(Companys Form S-3 (file no. 333-160710)).4.7
    
    Warrant issued to Capitol Securities Management, Inc. as of May
28, 2008 (Companys Form S-3 (file no. 333-160710)).4.8
    
    Warrant issued to Emerald Asset Advisors, LLC as of November 5,
2008 (Companys Form S-3 (file no. 333-160710)).4.9
    
    Form of Warrant issued to Messrs. Rick, Pizzirusso, Ries, Meyers
and Pace as of July 17, 2009 (Companys Form S-3 (file no. 333-160710)).4.10
    
    Warrant issued to RJ Aubrey IR Services LLC as of March 8,
2010. (Companys Form 10-Q filed May 7, 2010).4.11
    
    Warrant issued to Capitol Securities Management, Inc. as of
September 1, 2010 (Companys Form 8-K filed September 2, 2010).4.12
    
    Form of Amended and Restated Warrant issued to Messrs.
Rick, Pizzirusso, Ries, Meyers, Pace and Bailey as of September 1, 2010
(Companys Form 8-K filed September 2, 2010).4.13
    
    Warrant issued to DaVita Inc. as of February 16, 2011
(Companys Form 8-K filed February 23, 2011).
 2




---



##### 



*10.1
    
    Rockwell Medical Technologies, Inc. 1997 Stock Option Plan
(Companys Proxy Statement filed April 17, 2006).10.2
    
    Lease Agreement dated March 12, 2000 between the Company and DFW
Trade Center III Limited Partnership (Companys Form 10-KSB filed March 30,
2000.)10.3
    
    Lease Agreement dated October 23, 2000 between the Company and
International-Wixom, LLC (Companys Form 10-KSB filed April 2, 2001.)10.4
    
    Licensing Agreement between the Company and Charak LLC and Dr.
Ajay Gupta dated January 7, 2002 (with certain portions of the exhibit deleted
under a request for confidential treatment under Rule 24b-2 of the Securities
Exchange Act of 1934) (Companys Form 10-KSB filed April 1, 2002).10.10
    
    Second Amendment of Industrial Lease Agreement between Rockwell
Medical Technologies, Inc. and DCT DFW, LP dated August 17, 2005 (Companys
Form 8-K filed August 19, 2005).10.11
    
    Amending Agreement made the 16th day of January, 2006, by and
between Dr. Ajay Gupta, Charak LLC and Rockwell Medical Technologies, Inc.
(Companys Form 10-KSB filed March 31, 2006).*10.16
    
    Rockwell Medical Technologies, Inc. 2007 Long Term Incentive Plan (Companys
Proxy Statement filed April 18, 2007).10.17
    
    Consulting Agreement, dated as of October 3, 2007 (Companys
Form 8-K filed October 9, 2007).10.18
    
    Common Stock Purchase Agreement, dated November 28, 2007,
between the Company and certain Purchasers (Companys Form 8-K filed December
4, 2007).10.19
    
    Registration Rights Agreement, dated November 28, 2007, between
the Company and certain Purchasers (Companys Form 8-K filed December 4, 2007).*10.20
    
    Form of Nonqualified Stock Option Agreement (Director Version) (Companys
Form 8-K filed December 20, 2007).*10.21
    
    Form of Nonqualified Stock Option Agreement (Employee Version) (Companys
Form 8-K filed December 20, 2007).10.22
    
    Lease Agreement dated March 19, 2008 between the Company and
EZE Management Properties Limited Partners (Companys Form 10-K filed March 24,
2008).*10.23
    
    Amendment No. 1 to Rockwell Medical Technologies, Inc. 2007 Long Term
Incentive Plan (Companys Form 8-K filed May 30, 2008).10.24
    
    Advisory Agreement dated May 28, 2008 between the Company and
Capitol Securities Management, Inc. (Companys Form 10-Q filed August 12,
2008).10.25
    
    Mutual Release and Settlement Agreement dated September 24,
2008 by and among the Company, FWLL, LLC and ST Holdings, Inc (Companys Form
10-Q filed November 13, 2008).10.26
    
    Advisory Agreement dated September 30, 2008 between the Company
and RJ Aubrey IR Services LLC (Companys Form 10-Q filed November 13, 2008).10.27
    
    Advisory Agreement dated November 5, 2008 between the Company
and Emerald Asset Advisors, LLC (Companys Form 10-Q filed November 13, 2008).*10.28
    
    Form of Restricted Stock Award Agreement (Executive Version) (Companys Form
8-K filed November 25, 2008).10.29
    
    Amendment to Advisory Agreement dated November 21, 2008 between
the Company and Emerald Asset Advisors, LLC (Companys Form 10-K filed March 16,
2009).10.30
    
    Lease Renewal dated August 21, 2008 between the Company and
International-Wixom, LLC with respect to the Lease Agreement dated October 23,
2000 (Companys Form 10-K filed March 16, 2009).*10.32
    
    Amendment No. 2 to Rockwell Medical Technologies, Inc. 2007 Long Term
Incentive Plan (Companys Form 10-Q filed August 10, 2009).10.33
    
    Placement Agency Agreement with JMP Securities LLC and Wedbush
Securities Inc. dated September 29, 2009 (including the form of Subscription
Agreement included as Exhibit A thereto) (Companys Form 8-K filed September 30,
2009).10.34
    
    Advisory Agreement dated March 8, 2010 between the Company and
RJ Aubrey IR Services LLC (Companys Form 10-Q filed May 7, 2010).10.35
    
    Third Amendment to Industrial Lease Agreement between Rockwell
Medical Technologies, Inc. and DCT DFW, LP dated July 7, 2010 (Companys Form 8-K
filed on July 13, 2010).*10.36
    
    Amendment No. 3 to Rockwell Medical Technologies, Inc. 2007 Long Term Incentive
Plan (Companys Proxy Statement filed April 15, 2010).
 3




---



##### 



10.37
    
    Lease Renewal Agreement dated August 27, 2010, by and between
Rockwell Medical Technologies, Inc. and International-Wixom, LLC (Companys Form
8-K filed September 2, 2010).10.38
    
    Advisory Agreement dated September 1, 2010 between the Company
and Capitol Securities Management, Inc. (Companys Form 8-K filed September 2,
2010).10.39
    
    Products Purchase Agreement dated February 16, 2011, by and
between Rockwell Medical Technologies, Inc. and DaVita Inc (with certain
portions deleted pursuant to a request for confidential treatment under Rule
24b-2 of the Securities Exchange Act of 1934).10.40
    
    Agreement to Extend the Lease Agreement, Options to Purchase and
Option to Lease dated February 17, 2011, by and between Rockwell Medical
Technologies, Inc. and EZE Management Properties Limited Partnership (Companys
Form 8-K filed February 24, 2011).14.1
    
    Rockwell Medical Technologies, Inc. Code of Ethics (Companys
Proxy Statement filed April 23, 2004).21.1
    
    List of Subsidiaries (Companys Form SB-2 (file No. 333-31991)). **23.1
    
    Consent of Plante & Moran, PLLC (Companys Form 10-K filed March 7, 2011). **31.1
    
    Certification of Chief Executive Officer Pursuant to Rule 13a-14(a). **31.2
    
    Certification of Chief Financial Officer Pursuant to Rule 13a-14(a). **32.1
    
    Certification of the Chief Executive Officer and Chief Financial
Officer, Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906
of the Sarbanes-Oxley Act of 2002 (Companys Form 10-K filed March 7, 2011). **
 
 *
    
    Current management contracts or compensatory plans or arrangements.**
    
    Filed with Original Filing. 4




---



##### 



SIGNATURES
  ROCKWELL MEDICAL TECHNOLOGIES, INC. (Registrant)By:
    /s/ ROBERT L. CHIOINIRobert L. ChioiniPresident and Chief Executive Officer
Date: May 27, 2011 EXHIBIT INDEX TO FORM 10-K/A
  10.39
    
    Products Purchase Agreement dated February 16, 2011, by and between Rockwell Medical
Technologies, Inc. and DaVita Inc (with certain portions deleted pursuant to a request for
confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934).31.1
    
    Certification of Chief Executive Officer Pursuant to Rule 13a-14(a).31.2
    
    Certification of Chief Financial Officer Pursuant to Rule 13a-14(a).
 5