**Exhibit        10.40**

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|   | (i) | The                  risks involved in this offering, including the speculative nature                  of the                  investment; |
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|   | (ii) | The                  lack of liquidity and restrictions on transfer of the Common Stocks                  and; |
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|   | (iii) | The financial hazards involved in this offering,                including the risk of                losing Subscriber’s entire                investment. |
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|   | (b) | Subscriber                  acknowledges that it has prior investment experience, including                  investment                  in non-registered securities; that is recognizes the highly speculative                  nature of this investment and is able to bear the economic risk                  and is                  able to fend for itself; and that is has been advised by or have                  had an                  opportunity to employ the services of an investment adviser, attorney                  or                  accountant who is qualified by training and experience in business                  and                  financial matters to evaluate the merits and risks of such an investment                  and who has had the opportunity to review the Terms of the Offering                  and                  the Company’s publicly filed documents, links to which are provided in the                  Terms of the Offering. |
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|   | (c) | Subscriber                  represents that it and its investment advisor, attorney or accountant,                  if                  any, have been furnished by the Company, during the course of this                  transaction, with all information regarding the Company which such                  parties                  have requested or desire to know; that all documents which could                  be                  reasonably provided have been made available for the inspection                  and review                  of such parties; and that such parties have been afforded the opportunity                  to ask questions and receive answers from Daniel C. Montano, Co-President                  and Chief Executive Officer of the Company, Thomas Stegmann, M.D.,                  Co-President and Chief Medical Officer of the Company and other                  officers                  and directors of the Company, concerning the terms and conditions                  of the                  offering; and any additional information such parties                  requested. |
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|   | (d) | Subscriber                  acknowledges that there is a present public market for shares of                  the                  Company’s common stock, although transfer of the Common Stock purchased                  in                  this offering will be restricted. As a result, (i) Subscriber may                  not be                  able to liquidate its investment in the event of emergency, (ii)                  transferability is extremely limited and (iii) in the event of                  a                  disposition Subscriber could sustain a                  loss. |
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|   | (e) | The                  Common Stock is being purchased by Subscriber and not by any other                  person                  (whether or not a “U.S. Person” as that term is defined under Regulation                  S), with the Subscriber’s own funds and not with the funds of any other                  person and for the account of Subscriber, not as a nominee or agent                  and                  not for the account of any other person. On acceptance of this                  Subscription Agreement by the Company, no other person will have                  any                  interest, beneficial or otherwise, in the Common Stock. Subscriber                  is not                  obligated to transfer the Common Stock to any other person nor                  does                  Subscriber have any agreement or understanding to do so. Subscriber                  does                  not intend to subdivide Subscriber’s purchase of the Common Stock with any                  person. |
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|   | (f) | Subscriber                  is not purchasing the Common Stock for distribution or resale to                  others.                  Subscriber agrees that it will not sell or otherwise transfer the                  Common                  Stock unless any transfer complies with the resale provisions for                  “Category 3” companies set forth in Regulation S, is registered under the                  Act, or unless an exemption from such registration is available.                  Subscriber acknowledges that the Company by this Agreement has                  agreed not                  to transfer the Common Stock and may require an opinion of legal                  counsel                  satisfactory to the Company to the effect that a proposed transfer                  complies with the resale provisions set forth in Regulation S,                  is                  registered under the Act or is                  exempt. |
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|   | (g) | Subscriber                  understands that the Common Stock has not been registered under                  the Act,                  by reason of a claimed exemption under the provisions of the Act                  which                  depends, in part, upon the fact that Subscriber is not either a“U.S.                  Person” (as that term is defined in Regulation S) or purchasing the Common                  Stock for the benefit of a U.S. Person and on Subscriber’s agreement to                  restrict transfers of the Common Stock in the manner described                  for                  “Category 3” companies in Regulation                  S. |
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|   | (h) | Subscriber                  certifies that it is not a “U.S. Person” (as that term is defined in                  Regulation S) and is not acquiring the Common Stock for the account                  or                  benefit of any U.S. Person. It is agreed that the Company reserves                  the                  right to request documentation from the Subscriber to verify the                  foregoing                  representation. It is also agreed that the Company in its sole                  discretion                  may reject or limit any subscription and close the offer of Common                  Stock                  at any time. Subscriber acknowledges that it is aware that the                  Company is                  relying upon the foregoing representation relating to its non-U.S.                  status. |
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|   | (i) | If                  Subscriber is a corporation, partnership, trust or other entity,                  Subscriber was not formed, organized or incorporated under the                  laws of the                  United States. |
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|   | (j) | Subscriber,                  if not an individual, is empowered and duly authorized to enter                  into this                  Subscription Agreement under any and all governing documents, partnership                  agreements, trust instruments, pension plans, charter, certificate                  of                  incorporation, bylaw provisions or the like (the “Governing Documents”)                  and the person signing on behalf of Subscriber is empowered and                  duly                  authorized to do so by such Governing                  Documents. |
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|   | (k) | This                  Subscription Agreement constitutes a valid and binding agreement                  of                  Subscriber enforceable against Subscriber in accordance with its                  terms. |
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|   | (a) | Any                    breach of or inaccuracy in Subscriber’s representations, warranties or                    agreements herein; |
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|   | (b) | Any                    disposition of the Common Stock contrary to any of Subscriber’s                    representations, warranties or agreements herein;                    or |
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|   | (c) | Any                  action, suit or proceeding based on (i) a claim that any of said                  representations, warranties, agreements or information were inaccurate                  or                  misleading or otherwise cause for obtaining damages or redress                  from the                  Company or any director or officer of the Company under the Act                  or (ii)                  any disposition of the Common                  Stock. |
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| PURCHASER                      |   | Name                  and Address: |
|--------------------------------|--------|------------------------------------|
|                           |   |                               |
| ______________________________ |   | ______________________________     |
| Signature                      |   | ______________________________     |
|                           |   | ______________________________     |

| CARDIOVASCULAR                  BIOTHERAPEUTICS, INC.       |   | AMOUNT OF                SUBSCRIPTION                |
|-------------------------------------------------------------|--------|------------------------------------------------------|
|                                                        |        | ACCEPTED:                                            |
|                                                        |   |                                                 |
| By____________________________________                      |   | _________shares                of Common             |
| Daniel                  C. Montano, Chief Executive Officer |   | Stock for                a                Subscribed |
|                                                        |        | Amount                  of US $____________          |
|                                                        |   |                                                 |

| Type                  of Ownership (Check One) |
|------------------------------------------------|

|   |                                                     |   |                                                     |
|--------|----------------------------------------------------------|--------|----------------------------------------------------------|
| ___    | INDIVIDUAL                  OWNERSHIP                    | ___    | CORPORATION/LIMITED                                      |
|   | (One                  Signature Required)                |        | LIABILITY                  COMPANIES                     |
|   |                                                     |        | (Please                  include charter documents,      |
|   |                                                     |        | Certified                  Corporate Resolution          |
|   |                                                     |        | Authorizing                  signature and Incumbency    |
|   |                                                     |        | Certificate                  of signing Officer)         |
|   |                                                     |   |                                                     |
| ___    | PARTNERSHIP                                              | ___    | TRUST                                                    |
|   | (Please                  include a copy of the statement |        | (Please                  indicate name of trust, name of |
|   | of                  Partnership or Partnership           |        | include                  copy of the Trust Agreement     |
|   | Agreement                  authorizing signature.)       |        | or                  other authorization.)                |
|   |                                                     |        |                                                          |

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