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          High Blood PressureWomen's Health Topics High Blood Pressure
  
  					From the FDA Office of Women's Health
	
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REVISED! High Blood Pressure Medicine Booklet Download, Print and Share

There are various FDA-approved products that are currently available to treat high blood pressure. Learn more about your options and use this information to help you talk to your healthcare provider about your blood pressure medicine. You will also find some general information to help you use your medicine wisely.

**High blood pressure is a serious illness.**
High blood pressure is often called a “silent killer” because you can have it and not know it. You may not feel sick at first. **Over time, if you do not get treated for high blood pressure, you can get very sick or even die.**

High blood pressure can cause:

Kidney failure
	Stroke
	Blindness
	Heart attacks
	Heart disease***There is good news.*** There are life-saving medicines you can take every day to help control your high blood pressure. If you eat healthy foods, exercise, and take your medicine every day, you can help control your blood pressure.

Take your blood pressure medicine.
	It is important to take your blood pressure medicine every day. Take your medicine even when your blood pressure comes down... even when you do not feel bad. Do not stop taking your medicine until your healthcare provider says that it is OK.
	Many people who take high blood pressure medicine do not get any side effects. Like all medicines, high blood pressure medicines can sometimes cause side effects. You may have common problems like headaches, dizziness, or an upset stomach. These can be bothersome to how you feel every day but often lessen after the first few weeks of taking the medicine. If you find they continue to be bothersome to you, talk to your healthcare provider.**Understanding Your Blood Pressure: What Do the Numbers Mean?**
Blood pressure is the force of your blood pushing against the walls of your arteries as your heart pumps blood. High blood pressure, or hypertension, is when this force against your artery walls is too high. The higher your blood pressure levels, the more risk you have for other health problems such as heart disease, heart attack, and stroke.

When you have your blood pressure taken, you are told two numbers; for example, 120/80. Both numbers are important. The first (or top) number is your pressure when your heart beats **(systolic pressure)**. The second number is your pressure when your heart relaxes **(diastolic pressure)**. If the measurement reads 120 systolic and 80 diastolic, you would say, “120 over 80.” A normal blood pressure level is usually considered to be less than 120/80.

Talk with your healthcare provider about your numbers and how you can manage your blood pressure.

**High Blood Pressure and Pregnancy**
Some women have high blood pressure during pregnancy. This can put the mother and her baby at risk for problems during the pregnancy and after delivery. High blood pressure sometimes can be severe, which may lead to low birth weight or preterm birth. High blood pressure during pregnancy can raise your risk of high blood pressure in the future.

**There are different types of high blood pressure during pregnancy.**

**Gestational hypertension** is high blood pressure that you develop while you are pregnant. It starts after you are 20 weeks pregnant. In many cases, gestational hypertension does not harm you or your baby, and it goes away within 12 weeks after childbirth. Some women with gestational hypertension develop preeclampsia.

**Chronic hypertension** is high blood pressure that started before the 20th week of pregnancy or before you became pregnant. Some women may have had high blood pressure long before becoming pregnant but were unaware until they got their blood pressure checked at their prenatal visit. Sometimes chronic hypertension can also lead to preeclampsia.

**Preeclampsia** is a sudden increase in blood pressure after the 20th week of pregnancy and may include protein in the urine and very high blood pressure. It usually happens in the last trimester. In rare cases, symptoms may not start until after delivery. This is called **postpartum preeclampsia**. Preeclampsia may cause damage to some of your organs, such as your liver or kidneys. Preeclampsia can be serious or even life-threatening for both you and your baby.

The most important thing to do is talk with your healthcare provider about any blood pressure problems so you can get the right treatment and control your blood pressure—**before you get pregnant**. Getting treatment for high blood pressure is important before, during, and after pregnancy to decrease risks to you and your baby.

For more information about high blood pressure and pregnancy, go to https://www.cdc.gov/bloodpressure/pregnancy.htm.

**Types of High Blood Pressure Medicines**

You can use this information to help you talk to your healthcare provider about your blood pressure medicine.

Ask your healthcare provider about the benefits and risks of taking your medicine. This webpage only talks about some of the risks.
	Tell your healthcare provider about any problems you are having. Your healthcare provider will help you find the medicine that is best for you.
	Be sure to tell your healthcare provider if you are pregnant, nursing, or planning to get pregnant. Ask your healthcare provider to tell you about the benefits and risks of taking blood pressure medicine when you are pregnant.The different kinds of blood pressure medicines are listed below. The medicines are listed in groups. The brand names and generic names are given for the medicines in each group.

ACE Inhibitors
	Beta-Blockers
	Calcium Channel Blockers
	Peripherally Acting Alpha-Adrenergic Blockers
	Vasodilators
	Centrally-Acting Alpha Adrenergics
	Angiotension II Receptor Blockers
	Renin Inhibitors
	Combination Medicines
	Diuretics (sometimes called "water pills")**Angiotension-Converting Enzyme (ACE) Inhibitors**

Generic Name
			Brand Namebenzapril
			Lotensincaptopril
			*Generic Medicine Only*enalapril
			Epaned and Vasotecfosinopril
			*Generic Medicine Only*lisinopril
			Prinivil, Qbrelis, and Zestrilmoexipril
			*Generic Medicine Only*perindopril
			*Generic Medicine Only*quinapril
			Accuprilramipril
			Altacetrandolapril
			*Generic Medicine Only*

**ACE Inhibitors: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have kidney or liver problems, diabetes, heart problems, or a history of angioedema, talk to your healthcare provider about the risks of using this medicine.
	If you are taking aliskiren, diabetes medicines, diuretics (water pills), gold injections, lithium, neprilysin inhibitors (such as sacubitril), mTOR inhibitors, nonsteroidal anti-inflammatory drugs, or other medicines, talk to your healthcare provider about the risks of using this medicine.**Common Side Effects**

Cough
	Dizziness
	Feeling tired
	Headache
	Problems sleeping**Warning Signs**

**Seek medical attention if you have any of these signs:**

Abdominal pain
	Chest pain
	Fast heartbeat
	Jaundice
	Problems breathing or swallowing
	Signs of infection (e.g., sore throat, fever)
	Swelling in the face, eyes, lips, tongue, or legs**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Beta Blockers**

Generic Name
			Brand Nameacebutolol
			*Generic Medicine Only*atenolol
			Tenorminbetaxolol
			*Generic Medicine Only*bisoprolol
			*Generic Medicine Only*carvedilol
			Coregcarvedilol phosphate
			Coreg CRlabetalol
			Trandatemetoprolol succinate
			Kapspargo Sprinkle and Toprol-XLmetoprolol tartrate
			Lopressornadolol
			Corgardnebivolol
			Bystolicpindolol
			*Generic Medicine Only*propranolol
			Inderal, Inderal LA, and InnoPran XLtimolol
			*Generic Medicine Only*

**Beta-Blockers: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have a heart condition, kidney or liver problems, asthma, diabetes, or overactive thyroid, talk to your healthcare provider about the specific risks of using this medicine.
	If you are taking other medicines, talk to your healthcare provider about the risks of using beta-blockers.
	If you are planning to have cataract surgery, notify your eye doctor that you are using this medicine.
	Do not suddenly stop taking this medicine without the advice of your healthcare provider.**Common Side Effects**

Feeling tired
	Upset stomach
	Headache
	Dizziness
	Constipation or Diarrhea
	Feeling lightheaded**Warning Signs**

**Seek medical attention if you have any of these signs:**

Chest pain
	Problems breathing
	Slow or irregular heartbeat
	Swelling in the hands, feet, ankles, or legs**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Calcium Channel Blockers**

Generic Name
			Brand Nameamlodipine benzoate
			Katerziaamlodipine besylate
			Norvascdiltiazem
			Cardizem CD, Cardizem LA, Cartia XT, Diltzac, Tiazac, and Taztia XTfelodipine
			*Generic Medicine Only*isradipine
			*Generic Medicine Only*levamlodipine
			Conjuprinifedipine
			Adalat CC and Procardia Xnisoldipine
			Sularverapamil
			Calan SR, Verelan, and Verelan PM

**Calcium Channel Blockers: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have a heart condition, liver problems, or kidney problems, talk to your healthcare provider about the specific risks of using calcium channel blockers.
	If you are taking cimetidine, cyclosporine, fentanyl, sildenafil, simvastatin, tacrolimus, or other medicines, talk to your healthcare provider about the risks of using this medicine.**Common Side Effects**

Feeling drowsy
	Headache
	Upset stomach
	Ankle swelling
	Feeling flushed (warm)**Warning Signs**

**Seek medical attention if you have any of these signs**:

Chest pain
	Serious rashes
	Swelling of the face, eyes, lips, tongue, arms, or legs
	Fainting
	Irregular heartbeat**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Peripherally Acting Alpha-Adrenergic Blockers**

Generic Name
			Brand Namedoxazosin
			Cardura and Cardura XLphenoxybenzamine
			*Generic Medicine Only*prazosin
			Minipressterazosin
			*Generic Medicine Only*

**Peripherally Acting Alpha-Adrenergic Blockers: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have liver problems, talk to your healthcare provider about the risks of using this medicine.
	If you are taking other medicines, talk to your healthcare provider about the risks of using this medicine.
	If you are planning to have cataract surgery, notify your eye doctor that you are using this medicine.**Common Side Effects**

Dizziness
	Feeling tired
	Feeling light-headed
	Vision problems
	Decreased sexual ability**Warning Signs**

**Seek medical attention if you have any of these signs**:

Chest pain
	Fainting
	Swelling of the hands, feet, ankles, or legs
	Irregular heartbeat
	Prolonged or painful erection in men**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Vasodilators**

Generic Name
			Brand Namehydralazine
			*Generic Medicine Only*minoxidil
			*Generic Medicine Only*

**Vasodilators: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have heart disease or kidney problems, talk to your healthcare provider about the risks of using this medicine.
	If you are taking diuretics (water pills) or other medicines, talk to your healthcare provider about the risks of using this medicine.**Common Side Effects**

Upset stomach
	Dizziness
	Growth in body hair**Warning Signs**

**Seek medical attention if you have any of these signs**:

Fast heartbeat
	Fainting
	Chest pain
	Problems breathing
	Sudden weight gain
	Swelling of the hands, feet, ankles, or legs
	Skin tingling or numbness, skin crawling, or itching**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Angiotension II Antagonists**

Generic Name
			Brand Nameazilsartan
			Edarbicandesartan
			Atacandirbesartan
			Avaprolosartan
			Cozaarolmesartan
			Benicartelmisartan
			Micardisvalsartan
			Diovan

**Angiotension II Antagonists: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before you start using this medicine.
	If you have kidney problems, liver problems, diabetes, low blood volume, or low salt in your blood, talk to your healthcare provider about the risks of taking this medicine.
	If you are taking diuretics (water pills), aliskiren, antibiotics, cyclosporine, lithium, nonsteroidal anti-inflammatory drugs, potassium supplements, ritonavir, or other medicines, talk to your healthcare provider about the risks of taking this medicine.**Common Side Effects**

Cough
	Headache
	Sore throat
	Sinus problems
	Heartburn
	Dizziness
	Diarrhea
	Back pain**Warning Signs**

**Seek medical attention if you have any of these signs**:

Problems breathing
	Fainting
	Severe, chronic diarrhea with significant weight loss
	Swelling of the face, throat, lips, eyes, hands, feet, ankles, or legsr legs**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Centrally-Acting Alpha Adrenergics**

Generic Name
			Brand Nameclonidine
			Catapresclonidine
			Catapres–TTS-1, TTS-2, TTS-3 
			(Skin Patches)guanfacine
			*Generic Medicine Only*

**Centrally-Acting Alpha Adrenergics: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before you start using this medicine.
	If you have heart disease, kidney problems, or liver problems, talk to your healthcare provider before using this medicine.
	If you are taking antidepressants, antipsychotics, or other medicines, talk to your healthcare provider about the risks of using this medicine.
	Drinking alcohol may make side effects such as drowsiness, dizziness, or vision problems worse.
	Be careful when driving or operating machinery.
	Keep both used and unused skin patches out of the reach of children. Used patches still contain enough medicine to be harmful to a child.
	Tell your healthcare provider before you have an MRI scan if you are using the skin patch.
	Do not suddenly stop taking this medicine without the advice of your healthcare provider.**Common Side Effects**

Changes in vision
	Dizziness
	Dry eyes
	Dry mouth
	Headache
	Mild skin rash, itching, or redness (close to the patch)
	Decreased sexual ability
	Feeling drowsy or tired**Warning Signs**

**Seek medical attention if you have any of these signs**:

Allergic reaction (including hives, rash, or swelling in other parts of your body)
	Fainting
	Moderate-to-severe skin rash, itching, or redness
	Slow or irregular heartbeat
	Fever
	Swollen ankles or feet**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Renin Inhibitors**

Generic Name
			Brand NameAliskiren
			Tekturna

**Renin Inhibitors: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have diabetes, heart disease, or kidney problems, talk to your healthcare provider before using this medicine.
	If you are taking water pills (diuretics), cyclosporine, high blood pressure medicines, heart medicines, nonsteroidal anti-inflammatory drugs, potassium supplements, medicines to treat a fungus, or other medicines, talk to your healthcare provider about the risks of using this medicine.**Common Side Effects**

Cough
	Diarrhea
	Feeling light-headed
	Acid reflux
	Rash
	Upset stomach
	Abdominal pain**Warning Signs**

**Seek medical attention if you have any of these signs**:

Allergic reaction (difficulty breathing, hives, rash, or swelling in your whole body)
	Fainting
	Decreased urination
	Gout
	Kidney stones
	Seizures
	Swelling of the face, throat, lips, eyes, or tongue**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Combination Medicines**

Generic Name
			Brand Namealiskiren and hydrochlorothiazide
			Tekturna HCTamlodipine besylate and valsartan
			Exforgeamlodipine besylate and benazepril
			Lotrelamlodipine besylate and olmesartan
			Azoramlodipine besylate and perindopril
			Prestaliaamlodipine besylate and telmisartan
			Twynstaamlodipine besylate, hydrochlorothiazide, and valsartan
			Exforge HCTatenolol and chlorthalidone
			Tenoretic 50, Tenoretic 100benazepril and hydrochlorothiazide
			Lotensin HCTcandesartan and hydrochlorothiazide
			Atacand HCTcaptopril and hydrochlorothiazide
			*Generic Medicine Only*enalapril and hydrochlorothiazide
			Vasereticfosinopril and hydrochlorothiazide
			*Generic Medicine Only*hydrochlorothiazide and irbesartan
			Avalidehydrochlorothiazide and lisinopril
			Zestoretichydrochlorothiazide and metoprolol succinate
			Dutoprolhydrochlorothiazide and metoprolol tartrate
			Lopressor HCThydrochlorothiazide and olmesartan
			Benicar HCThydrochlorothiazide and quinapril
			Accuretic and Quinaretichydrochlorothiazide and telmisartan
			Micardis HCTbisoprolol and hydrochlorothiazide
			Ziachydrochlorothiazide and losartan
			Hyzaarhydrochlorothiazide and metoprolol tartrate
			*Generic Medicine Only*hydrochlorothiazide and moexipril
			*Generic Medicine Only*amlodipine besylate, hydrochlorothiazide, and olmesartan
			Tribenzortrandolapril and verapamil
			Tarkahydrochlorothiazide and valsartan
			Diovan HCTchlorthalidone and zilsartan
			Edarbyclor

**Combination Drugs: What You Should Know**

These medicines are made up of two or more different kinds of blood pressure medicines. Look for the generic or brand names of these medicines on one of the other lists in this guide.

**Warnings and Side Effects**

The warnings and side effects for these medicines will be the same as those listed for each of the generic medicines.

**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Other Combination Medicines**

**Generic Name**
			**Brand Name**amlodipine besylate and atorvastatin
			Caduetamlodipine besylate and celecoxib
			Consensi

**Other Combination Medicines: What You Should Know**

Caduet is made up of two different kinds of medicines. Amlodipine is a blood pressure medicine. Atorvastatin is a cholesterol-lowering medicine.
	Consensi is made up of two different kinds of medicines. Amlodipine is a blood pressure medicine. Celecoxib is a medicine used to treat osteoarthritis.
	Look for the generic or brand names of amlodipine on the list of calcium channel blockers in this guide. The warnings and side effects for amlodipine will be the same as those listed earlier for calcium channel blockers.
	For the most complete and up-to-date information about the warnings and side effects for each  medicine of atorvastatin and celecoxib, check http:/www.accessdata.fda.gov/scripts/cder/drugsatfda/.**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have asthma, diabetes, stomach ulcers, heart disease, kidney problems, liver problems, or thyroid problems, talk to your healthcare provider before using this medicine.
	If you are taking aspirin, blood thinners, corticosteroids, cyclosporine, tacrolimus, antiviral medicines, antibiotics, antifungal medicines, cimetidine, sildenafil, oral contraceptives, or other medicines, talk to your healthcare provider about the risks of using this medicine.**Common Side Effects**

Swelling of the legs or ankles
	Muscle or joint pain (mild)
	Headache
	Diarrhea or constipation
	Feeling dizzy
	Feeling tired or sleepy
	Gas
	Rash
	Nausea
	Face feels hot or warm**Warning Signs**

**Seek medical attention if you have any of these signs:**

Chest pain
	Allergic reaction (difficulty breathing, hives, rash, or swelling in your whole body)
	Weakness in part of your body
	Slurred speech
	Muscle problems such as weakness, tenderness, or pain that happens without a good reason (e.g., exercise or injury)
	Bloody vomit or bowel movement
	Brown or dark-colored urine
	Skin or eyes look yellow
	Fast or irregular heartbeat
	Feel more tired than usual
	Serious skin rash, itching, or redness
	Stomach or intestinal pain**Diuretics (sometimes called "water pills")**

Generic Name
			Brand Nameamiloride and hydrochlorothiazide
			Midamorchlorothiazide
			Diurilchlorthalidone
			*Generic Medicine Only*eplerenone
			Insprafurosemide
			Lasixhydrochlorothiazide
			Microzidehydrochlorothiazide and spironolactone
			Aldactazidehydrochlorothiazide and triamterene
			Dyazide, Maxzide, and Maxzide-25indapamide
			*Generic Medicine Only*spironolactone
			Aldactone and CaroSpirtorsemide
			Demadexmetolazone
			Zaroxolyn

**Diuretics: What You Should Know**

**Warnings**

If you are pregnant or nursing, talk to your healthcare provider before using this medicine.
	If you have kidney or liver problems, talk to your healthcare provider about the risks of using this medicine.
	If you are taking potassium supplements, lithium, cyclosporine, tacrolimus, nonsteroidal anti-inflammatory drugs, antifungal drugs, antiviral drugs, or other medicines, talk to your healthcare provider about the risks of using this medicine.**Common Side Effects**

Dizziness
	Fainting
	Frequent urination
	Headache
	Upset stomach**Warning Signs**

**Seek medical attention if you have any of these signs**:

Sudden vision changes or eye pain
	Severe rash
	Problems breathing
	Irregular heartbeat
	Feeling thirsty
	Muscle cramps or weakness
	Tingling or numbness in hands, arms, legs, or feet
	Gout**For the most complete and up-to-date information about the risks and side effects for each medicine, check Drugs@FDA.**

**Questions To Ask Your Doctor**

What is the name of the medicine I am taking?
	What are the potential side effects?
	What other prescription medicines should I avoid while taking my high blood pressure medicine?
	What foods (such as grapefruit juice), herbs (like St. John’s wort), or over-the-counter medicine should I avoid?
	When should I take each medicine? How many times per day do I take each medicine?
	Can I take my medicines if I am pregnant or nursing?**Learn More About Pregnancy Registries**
























Resources For You

FDA Office of Women's Health Resources
	Heart Health for Women
		Women and Diabetes
	National Heart, Lunch and Blood Institute Resources
	High Blood Pressure
	NIH National Library of Medicine MedlinePlus
	High Blood Pressure and Pregnancy
	Centers for Disease Control and Prevention
	High Blood Pressure during Pregnancy

**This guide should not be used in place of talking to your healthcare provider or reading the label on your medicine bottle. The medicine and risk information in this guide may change and is not all-inclusive. High blood pressure medicines and information in this guide are current as of February 2021. 
For the most complete and up-to-date information about the risks and side effects of each medicine, check Drugs@FDA.**

                                                                                  Content current as of:
      02/01/2021
              
              
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