Exhibit 10.12



AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT

PHARSIGHT CORPORATION



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TABLE OF CONTENTS



|  |  |                                |  |                                                                        |  |   
|- |  | ------------------------------ |  | ---------------------------------------------------------------------- |  | --
|  |  |                                |  | Page                                                                  
|1 |  | ACCOUNTING AND OTHER TERMS     |  | 4                                                                     
|  |  |                               
|2 |  | LOAN AND TERMS OF PAYMENT      |  | 4                                                                     
|  |  | 2.1                            |  | Promise to Pay.                                                        |  | 4 
|  |  | 2.2                            |  | Termination of Commitment to Lend.                                     |  | 5 
|  |  | 2.3                            |  | Overadvances.                                                          |  | 5 
|  |  | 2.4                            |  | Interest Rate, Payments.                                               |  | 5 
|  |  | 2.5                            |  | Fees.                                                                  |  | 5 
|  |  |                               
|3 |  | CONDITIONS OF LOANS            |  | 6                                                                     
|  |  | 3.1                            |  | Conditions Precedent to Initial Credit Extension.                      |  | 6 
|  |  | 3.2                            |  | Conditions Precedent to all Credit Extensions.                         |  | 6 
|  |  |                               
|4 |  | CREATION OF SECURITY INTEREST  |  | 6                                                                     
|  |  | 4.1                            |  | Grant of Security Interest.                                            |  | 6 
|  |  | 4.2                            |  | Required Cash Collateral.                                              |  | 6 
|  |  | 4.3                            |  | Authorization of File.                                                 |  | 7 
|  |  |                               
|5 |  | REPRESENTATIONS AND WARRANTIES |  | 7                                                                     
|  |  | 5.1                            |  | Due Organization and Authorization.                                    |  | 7 
|  |  | 5.2                            |  | Collateral.                                                            |  | 7 
|  |  | 5.3                            |  | Litigation.                                                            |  | 7 
|  |  | 5.4                            |  | No Material Adverse Change in Financial Statements.                    |  | 7 
|  |  | 5.5                            |  | Solvency.                                                              |  | 8 
|  |  | 5.6                            |  | Regulatory Compliance.                                                 |  | 8 
|  |  | 5.7                            |  | Subsidiaries.                                                          |  | 8 
|  |  | 5.8                            |  | Full Disclosure.                                                       |  | 8 
|  |  |                               
|6 |  | AFFIRMATIVE COVENANTS          |  | 8                                                                     
|  |  | 6.1                            |  | Government Compliance.                                                 |  | 8 
|  |  | 6.2                            |  | Financial Statements, Reports, Certificates.                           |  | 8 
|  |  | 6.3                            |  | Inventory; Returns.                                                    |  | 9 
|  |  | 6.4                            |  | Taxes.                                                                 |  | 9 
|  |  | 6.5                            |  | Insurance.                                                             |  | 9 
|  |  | 6.6                            |  | Primary Accounts.                                                      |  | 9 
|  |  | 6.7                            |  | Financial Covenants.                                                   |  | 10
|  |  | 6.8                            |  | Further Assurances.                                                    |  | 10
|  |  |                               
|7 |  | NEGATIVE COVENANTS             |  | 10                                                                    
|  |  | 7.1                            |  | Dispositions.                                                          |  | 10
|  |  | 7.2                            |  | Changes in Business, Ownership, Management or Locations of Collateral. |  | 10
|  |  | 7.3                            |  | Mergers or Acquisitions.                                               |  | 10
|  |  | 7.4                            |  | Indebtedness.                                                          |  | 11
|  |  | 7.5                            |  | Encumbrance.                                                           |  | 11
|  |  | 7.6                            |  | Distributions; Investments.                                            |  | 11
|  |  | 7.7                            |  | Transactions with Affiliates.                                          |  | 11
|  |  | 7.8                            |  | Subordinated Debt.                                                     |  | 11
|  |  | 7.9                            |  | Compliance.                                                            |  | 11
|  |  |                               
|8 |  | EVENTS OF DEFAULT              |  | 11                                                                    
|  |  | 8.1                            |  | Payment Default.                                                       |  | 11



2



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|                      |  |                                            |  |                                      |  |   
|--------------------- |  | ------------------------------------------ |  | ------------------------------------ |  | --
|                      |  | 8.2                                        |  | Covenant Default.                    |  | 12
|                      |  | 8.3                                        |  | Material Adverse Change.             |  | 12
|                      |  | 8.4                                        |  | Attachment.                          |  | 12
|                      |  | 8.5                                        |  | Insolvency.                          |  | 12
|                      |  | 8.6                                        |  | Other Agreements.                    |  | 12
|                      |  | 8.7                                        |  | Judgments.                           |  | 12
|                      |  | 8.8                                        |  | Misrepresentations.                  |  | 13
|                      |  |                                           
|9                     |  | BANKS RIGHTS AND REMEDIES                 |  | 13                                  
|                      |  | 9.1                                        |  | Rights and Remedies.                 |  | 13
|                      |  | 9.2                                        |  | Power of Attorney.                   |  | 13
|                      |  | 9.3                                        |  | Bank Expenses.                       |  | 14
|                      |  | 9.4                                        |  | Bank's Liability for Collateral.     |  | 14
|                      |  | 9.5                                        |  | Remedies Cumulative.                 |  | 14
|                      |  | 9.6                                        |  | Demand Waiver.                       |  | 14
|                      |  |                                           
|10                    |  | NOTICES                                    |  | 14                                  
|                      |  |                                           
|11                    |  | CHOICE OF LAW, VENUE AND JURY TRIAL WAIVER |  | 14                                  
|                      |  |                                           
|12                    |  | GENERAL PROVISIONS                         |  | 15                                  
|                      |  | 12.1                                       |  | Successors and Assigns.              |  | 15
|                      |  | 12.2                                       |  | Indemnification.                     |  | 15
|                      |  | 12.3                                       |  | Time of Essence.                     |  | 15
|                      |  | 12.4                                       |  | Severability of Provision.           |  | 15
|                      |  | 12.5                                       |  | Amendments in Writing, Integration.  |  | 15
|                      |  | 12.6                                       |  | Counterparts.                        |  | 15
|                      |  | 12.7                                       |  | Survival.                            |  | 15
|                      |  | 12.8                                       |  | Confidentiality.                     |  | 15
|                      |  | 12.9                                       |  | Effect of Amendment and Restatement. |  | 16
|                      |  | 12.10                                      |  | Attorneys Fees, Costs and Expenses. |  | 16
|                      |  |                                           
|13                    |  | DEFINITIONS                                |  | 16                                  
|                      |  | 13.1                                       |  | Definitions.                         |  | 16
|                      | 
|Pharsight Corporation |  | 4                                         



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This AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT (Agreement) dated as of the
Effective Date, between SILICON VALLEY BANK (Bank), whose address is 3003 Tasman Drive, Santa Clara, California 95054 and PHARSIGHT CORPORATION (Borrower), whose address is 800 West El Camino Real, Suite 200, Mountain View,
California 94040.



RECITALS



A. Bank and Borrower are parties to that certain Loan and Security Agreement,
dated June 13, 2001, as amended and that certain Export and Import Loan and Security Agreement (collectively, the Original Agreement).



B. Bank and Borrower are parties to that certain UCC Financing Statement filed with the Secretary of State of Delaware on June 25, 2002 as file number
21559701.



C. Borrower and Bank desire in this Agreement to set
forth their agreement with respect to a working capital and term loan and to amend and restate in its entirety without novation the Original Agreement in accordance with the provisions herein.



AGREEMENT



The parties agree as follows:



|1 | ACCOUNTING AND OTHER TERMS
|- | --------------------------



Accounting terms not defined in this Agreement will be construed following GAAP. Calculations and determinations must be made following GAAP. The
term financial statements includes the notes and schedules. The terms including and includes always mean including (or includes) without limitation, in this or any Loan Document.



|2 | LOAN AND TERMS OF PAYMENT
|- | -------------------------



|2.1 | Promise to Pay.
|--- | ---------------



Borrower promises to pay Bank the unpaid principal amount of all Credit Extensions and interest on the unpaid principal amount of the Credit Extensions.



|2.1.1 | Revolving Advances.
|----- | -------------------



(a) Bank will make Advances not exceeding the lesser of the Committed Revolving Line orthe Borrowing Base. Amounts borrowed under this Section may
be repaid and reborrowed during the term of this Agreement.



(b) To obtain an Advance, Borrower must notify Bank by facsimile or telephone by 12:00 p.m. Pacific time on the Business Day the Advance is to be made. Borrower must promptly confirm the notification by delivering to Bank the
Payment/Advance Form attached as Exhibit B. Bank will credit Advances to Borrowers deposit account. Bank may make Advances under this Agreement based on instructions from a Responsible Officer or his or her designee or without instructions if
the Advances are necessary to meet Obligations which have become due. Bank may rely on any telephone notice given by a person whom Bank believes is a Responsible Officer or designee. Borrower will indemnify Bank for any loss Bank suffers due to such
reliance.



(c) The Committed Revolving Line terminates on the
Revolving Maturity Date, when all Advances are immediately payable.



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|2.1.2 | Term Loan.
|----- | ----------



(a) The outstanding balance under the Term Loan will continue to amortize and be payable as follows:



(b) Borrower will pay 25 equal installments of principal of $72,916.67 plus
accrued interest (the Term Loan Payment). Each Term Loan Payment is payable on the 1st of each month during the term of the loan. Borrowers final Term Loan Payment, due on June 1, 2006, includes all outstanding Term Loan principal
and accrued interest.



|2.2 | Termination of Commitment to Lend.
|--- | ----------------------------------



Banks obligation to lend the undisbursed portion of the Obligations will terminate if, in Banks sole discretion, there has been a
material adverse change in the general affairs, management, results of operation, condition (financial or otherwise) or the prospect of repayment of the Obligations, or there has been any material adverse deviation by Borrower from the most recent
business plan of Borrower presented to and accepted by Bank prior to the execution of this Agreement.



|2.3 | Overadvances.
|--- | -------------



If Borrowers Obligations under Section 2.1.1 exceed the lesser of either (i) the Committed Revolving Line or (ii) the Borrowing Base,
Borrower must immediately pay Bank the excess.



|2.4 | Interest Rate, Payments.
|--- | ------------------------



(a) Interest Rate. (i) Advances accrue interest on the outstanding principal balance at a per annum rate of 0.5 of one percentage point above the Prime
Rate; and (ii) the Term Loan accrues interest at a per annum rate of 1.25 percentage points above the Prime Rate. After an Event of Default, Obligations accrue interest at 5 percent above the rate effective immediately before the Event of Default.
The interest rate increases or decreases when the Prime Rate changes. Interest is computed on a 360 day year for the actual number of days elapsed.



(b) Payments. Interest due on the Committed Revolving Line is payable on the 26th of each month. Bank may debit any of Borrowers deposit accounts
including Account Number 3300027682 for principal and interest payments owing or any amounts Borrower owes Bank. Bank will promptly notify Borrower when it debits Borrowers accounts. These debits are not a set-off. Payments received after
12:00 noon Pacific time are considered received at the opening of business on the next Business Day. When a payment is due on a day that is not a Business Day, the payment is due the next Business Day and additional interest shall accrue.



|2.5 | Fees.
|--- | -----



Borrower will pay:



(a) Facility Fee. A fully earned, non-refundable Facility Fee of $10,500 for the Committed Revolving Line due on the Effective Date; and



(b) Bank Expenses. All Bank Expenses (including reasonable attorneys
fees and reasonable expenses) incurred through and after the date of this Agreement, are payable when due.



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|3 | CONDITIONS OF LOANS
|- | -------------------



|3.1 | Conditions Precedent to Initial Credit Extension.
|--- | -------------------------------------------------



Banks obligation to make the initial Credit Extension is subject to the condition precedent that it receive the agreements, documents and fees it
requires.



|3.2 | Conditions Precedent to all Credit Extensions.
|--- | ----------------------------------------------



Banks obligations to make each Credit Extension, including the initial Credit Extension, is subject to the following:



(a) timely receipt of any Payment/Advance Form; and



(b) the representations and warranties in Section 5 must be materially
true on the date of the Payment/Advance Form and on the effective date of each Credit Extension and no Event of Default may have occurred and be continuing, or result from the Credit Extension. Each Credit Extension is Borrowers representation
and warranty on that date that the representations and warranties of Section 5 remain true.



|4 | CREATION OF SECURITY INTEREST
|- | -----------------------------



|4.1 | Grant of Security Interest.
|--- | ---------------------------



Borrower grants Bank a continuing security interest in all presently existing and later acquired Collateral to secure all Obligations and performance of
each of Borrowers duties under the Loan Documents. Except for Permitted Liens, any security interest will be a first priority security interest in the Collateral. Bank may place a hold on any deposit account pledged as Collateral.
Notwithstanding the foregoing, the security interest granted herein does not extend to and the term Collateral does not include any Intellectual Property; provided that the Collateral shall include Intellectual Property to the extent,
and only to the extent, a security interest in any portion of the Intellectual Property is required in order to permit Bank to hold a perfected security interest in the other Collateral, including, without limitation, Accounts arising from the
license, publication or other exploitation of Copyrights or other Intellectual Property; provided, further, that Borrower shall execute and deliver a Negative Pledge Agreement, attached hereto as Exhibit F, satisfactory to Bank with respect to the
Intellectual Property, and upon any breach thereof, the Collateral shall be deemed to include, retroactively from the date of Original Agreement, the Intellectual Property. If the Agreement is terminated, Banks lien and security interest in
the Collateral will continue until Borrower fully satisfies its Obligations.



|4.2 | Required Cash Collateral.
|--- | -------------------------



In the event any financial covenant set forth in Section 6.7 is breached, and in addition to all of Banks other rights and remedies hereunder upon
the occurrence of an Event of Default, Borrower shall immediately deliver to Bank, for deposit with Bank, cash in the amount of at least 105% of the then aggregate outstanding balance of the Term Loan, to be held by Bank in an interest bearing time
deposit account subject to a perfected, first priority security interest securing all Obligations. Banks hold on such cash shall be released if: (a) Bank shall have waived its other rights and remedies as to such existing financial covenant
breach or breaches and no other Event of Default has occurred and is continuing; and (b) Bank shall have determined that Borrower is no longer in violation of any of the financial covenants in Section 6.7 previously breached.



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|4.3 | Authorization of File.
|--- | ----------------------



Borrower authorizes Bank to file financing statements without notice to Borrower, with all appropriate jurisdictions, as Bank deems appropriate, in order
to perfect or protect Banks interest in the Collateral.



|5 | REPRESENTATIONS AND WARRANTIES
|- | ------------------------------



Borrower represents and warrants as follows:



|5.1 | Due Organization and Authorization.
|--- | -----------------------------------



Borrower and each Subsidiary is duly existing and in good standing in its state of formation and qualified and licensed to do business in, and in good
standing in, any state in which the conduct of its business or its ownership of property requires that it be qualified, except where the failure to do so could not reasonably be expected to cause a Material Adverse Change. Borrower has not changed
its state of formation or its organizational structure or type or any organizational number (if any) assigned by its jurisdiction of formation.



The execution, delivery and performance of the Loan Documents have been duly authorized, and do not conflict with Borrowers formation documents, nor
constitute an event of default under any material agreement by which Borrower is bound. Borrower is not in default under any agreement to which or by which it is bound in which the default could reasonably be expected to cause a Material Adverse
Change.



|5.2 | Collateral.
|--- | -----------



Borrower has good title to the Collateral, free of Liens except Permitted Liens or Borrower has Rights to each asset that is Collateral. The Eligible
Accounts are bona fide, existing obligations, and the service or property has been performed or delivered to the account debtor or its agent for immediate shipment to and unconditional acceptance by the account debtor. Borrower has no notice of any
actual or imminent Insolvency Proceeding of any account debtor whose accounts are an Eligible Account in any Borrowing Base Certificate. All Inventory is in all material respects of good and marketable quality, free from material defects. Borrower
is the sole owner of the Intellectual Property, except for exclusive or non-exclusive license limits the use and application of the licensed Intellectual property to specific indications and geographic regions and does not impair Borrowers
ability to commercialize its Intellectual Property in its United States of America business markets. Each Patent is valid and enforceable and no part of the Intellectual Property has been judged invalid or unenforceable, in whole or in part, and no
claim has been made that any part of the Intellectual Property violates the rights of any third party.



|5.3 | Litigation.
|--- | -----------



Except as shown in the Schedule, there are no actions or proceedings pending or, to the knowledge of Borrowers Responsible Officers, threatened by
or against Borrower or any Subsidiary in which a likely adverse decision could reasonably be expected to cause a Material Adverse Change.



|5.4 | No Material Adverse Change in Financial Statements.
|--- | ---------------------------------------------------



All consolidated financial statements for Borrower, and any Subsidiary, delivered to Bank fairly present in all material respects Borrowers
consolidated financial condition and Borrowers consolidated results of operations. There has not been any material deterioration in Borrowers consolidated financial condition since the date of the most recent financial statements
submitted to Bank.



7



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|5.5 | Solvency.
|--- | ---------



The fair salable value of Borrowers assets (including goodwill minus disposition costs) exceeds the fair value of its liabilities; the Borrower is
not left with unreasonably small capital after the transactions in this Agreement; and Borrower is able to pay its debts (including trade debts) as they mature.



|5.6 | Regulatory Compliance.
|--- | ----------------------



Borrower is not an investment company or a company controlled by an investment company under the Investment Company
Act. Borrower is not engaged as one of its important activities in extending credit for margin stock (under Regulations T and U of the Federal Reserve Board of Governors). Borrower has complied in all material respects with the Federal Fair Labor
Standards Act. Borrower has not violated any laws, ordinances or rules, the violation of which could reasonably be expected to cause a Material Adverse Change. None of Borrowers or any Subsidiarys properties or assets has been used by
Borrower or any Subsidiary or, to the best of Borrowers knowledge, by previous Persons, in disposing, producing, storing, treating, or transporting any hazardous substance other than legally. Borrower and each Subsidiary has timely filed all
required tax returns and paid, or made adequate provision to pay, all material taxes, except those being contested in good faith with adequate reserves under GAAP. Borrower and each Subsidiary has obtained all consents, approvals and authorizations
of, made all declarations or filings with, and given all notices to, all government authorities that are necessary to continue its business as currently conducted, except where the failure to do so could not reasonably be expected to cause a
Material Adverse Change.



|5.7 | Subsidiaries.
|--- | -------------



Borrower does not own any stock, partnership interest or other equity securities except for Permitted Investments.



|5.8 | Full Disclosure.
|--- | ----------------



No written representation, warranty or other statement of Borrower in any certificate or written statement given to Bank (taken together with all such
written certificates and written statements to Bank) contains any untrue statement of a material fact or omits to state a material fact necessary to make the statements contained in the certificates or statements not misleading.



|6 | AFFIRMATIVE COVENANTS
|- | ---------------------



Borrower will do all of the following for so long as Bank has an obligation to lend, or there are outstanding Obligations:



|6.1 | Government Compliance.
|--- | ----------------------



Borrower will maintain its and all Subsidiaries legal existence and good standing in its jurisdiction of formation and maintain qualification in
each jurisdiction in which the failure to so qualify would reasonably be expected to cause a material adverse effect on Borrowers business or operations. Borrower will comply, and have each Subsidiary comply, with all laws, ordinances and
regulations to which it is subject, noncompliance with which could have a material adverse effect on Borrowers business or operations or would reasonably be expected to cause a Material Adverse Change.



|6.2 | Financial Statements, Reports, Certificates.
|--- | --------------------------------------------



(a) Borrower will deliver to Bank: (i) as soon as available, but no later than 30 days after the last day of each month, a company prepared consolidated
balance sheet and income



8



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statement covering Borrowers consolidated operations during the period certified by a Responsible Officer and in a
form acceptable to Bank; (ii) as soon as available, but no later than 5 days of filing with the Securities and Exchange Commission, audited consolidated financial statements prepared under GAAP, consistently applied, together with an unqualified
opinion on the financial statements from an independent certified public accounting firm reasonably acceptable to Bank; (iii) a prompt report of any legal actions pending or threatened against Borrower or any Subsidiary that could result in damages
or costs to Borrower or any Subsidiary of $100,000 or more; and (iv) budgets, sales projections, operating plans or other financial information Bank reasonably requests.



(b) Within 20 days after the last day of each month, Borrower will deliver to Bank a Borrowing Base Certificate signed by a
Responsible Officer in the form of Exhibit C, with aged listings of accounts receivable and accounts payable and deferred revenue schedules.



(c) Within 30 days after the last day of each month, Borrower will deliver to Bank with the monthly financial statements a Compliance Certificate signed
by a Responsible Officer in the form of Exhibit D.



(d) On or
prior to April 30thof each year, Borrower will deliver to Bank its board of directors approved operating
plan.



(e) Allow Bank to audit Borrowers Collateral at
Borrowers expense. Such audits will be conducted no more often than every 6 months unless an Event of Default has occurred and is continuing.



|6.3 | Inventory; Returns.
|--- | -------------------



Borrower will keep all Inventory in good and marketable condition, free from material defects. Returns and allowances between Borrower and its account
debtors will follow Borrowers customary practices as they exist at execution of this Agreement. Borrower must promptly notify Bank of all returns, recoveries, disputes and claims, that involve more than $50,000.



|6.4 | Taxes.
|--- | ------



Borrower will make, and cause each Subsidiary to make, timely payment of all material federal, state, and local taxes or assessments and will deliver to
Bank, on demand, appropriate certificates attesting to the payment.



|6.5 | Insurance.
|--- | ----------



Borrower will keep its business and the Collateral insured for risks and in amounts, as Bank may reasonably request. Insurance policies will be in a form,
with companies, and in amounts that are satisfactory to Bank in Banks reasonable discretion. All property policies will have a lenders loss payable endorsement showing Bank as an additional loss payee and all liability policies will show
the Bank as an additional insured and provide that the insurer must give Bank at least 20 days notice before canceling its policy. At Banks request, Borrower will deliver certified copies of policies and evidence of all premium payments.
Proceeds payable under any policy will, at Banks option, be payable to Bank on account of the Obligations.



|6.6 | Primary Accounts.
|--- | -----------------



Borrower will maintain its primary operating accounts with Bank, which relationship shall include Borrower maintaining 85% of its cash and cash
equivalents in deposit accounts or investment accounts at Bank or one of its affiliates



9



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|6.7 | Financial Covenants.
|--- | --------------------



Borrower will maintain as of the last day of each month (unless otherwise stated):



(i) Quick Ratio (Adjusted). A ratio of cash and cash equivalents plus accounts receivables divided by Current
Liabilities minus Deferred Revenue of at least (i) 1.50 to 1.00 for the months ending April 30, 2004; May 31, 2004, June 30, 2004 and July 31, 2004; (ii) 1.75 to 1.00 for the months ending August 31, 2004, September 30, 2004, October 31, 2004 and
November 30, 2004 and (iii) 2.00 to 1.00 for the months ending December 31, 2004 and thereafter.



(ii) Profitability/Loss (tested quarterly). Borrower will have a net profit of $1.00, provided, however, Borrower may suffer a loss not to exceed
$500,000 for quarter ending June 30, 2004.



|6.8 | Further Assurances.
|--- | -------------------



Borrower will execute any further instruments and take further action as Bank reasonably requests to perfect or continue Banks security interest in
the Collateral or to effect the purposes of this Agreement.



|7 | NEGATIVE COVENANTS
|- | ------------------



For so long as Bank has an obligation to lend or there are any outstanding Obligations, Borrower shall not, without Banks prior written consent
(which shall be a matter of its good faith business judgment), do any of the following:



|7.1 | Dispositions.
|--- | -------------



Convey, sell, lease, transfer or otherwise dispose of (collectively Transfer), or permit any of its Subsidiaries to Transfer, all or any part
of its business or property, except for Transfers (i) of Inventory in the ordinary course of business; (ii) of non-exclusive licenses and similar arrangements for the use of the property of Borrower or its Subsidiaries in the ordinary
course of business; or (iii) of worn-out or obsolete Equipment.



|7.2 | Changes in Business, Ownership, Management or Locations of Collateral.
|--- | ----------------------------------------------------------------------



Engage in or permit any of its Subsidiaries to engage in any business other than the businesses currently engaged in by Borrower or reasonably related
thereto or have a material change in its ownership or management of greater than 25% (other than by the sale of Borrowers equity securities in a public offering or to venture capital investors so long as Borrower identifies the venture capital
investors prior to the closing of the investment). Borrower will not, without at least 30 days prior written notice, relocate its chief executive office, change its state of formation (including reincorporation), change its organizational number or
name or add any new offices or business locations (such as warehouses) in which Borrower maintains or stores over $5,000 in Collateral.



|7.3 | Mergers or Acquisitions.
|--- | ------------------------



Merge or consolidate, or permit any of its Subsidiaries to merge or consolidate, with any other Person, or acquire, or permit any of its Subsidiaries to
acquire, all or substantially all of the capital stock or property of another Person, except where (i) no Event of Default has occurred and is continuing or would result from such action during the term of this Agreement and (ii) such
transaction would not result in a decrease of more than 25% of Tangible Net Worth. A Subsidiary may merge or consolidate into another Subsidiary or into Borrower.



10



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|7.4 | Indebtedness.
|--- | -------------



Create, incur, assume, or be liable for any Indebtedness, or permit any Subsidiary to do so, other than Permitted Indebtedness.



|7.5 | Encumbrance.
|--- | ------------



Create, incur, or allow any Lien on any of its property, or assign or convey any right to receive income, including the sale of any Accounts, or permit
any of its Subsidiaries to do so, except for Permitted Liens, or permit any Collateral not to be subject to the first priority security interest granted here, subject to Permitted Liens.



|7.6 | Distributions; Investments.
|--- | ---------------------------



Directly or indirectly acquire or own any Person, or make any Investment in any Person, other than Permitted Investments, or permit any of its
Subsidiaries to do so. Pay any dividends or make any distribution or payment or redeem, retire or purchase any capital stock. Notwithstanding the foregoing, Borrower will be allowed to pay any dividends (provided that cash dividends shall not exceed
$600,000 per year) and payments in connection with redemptions as permitted or required pursuant to the terms of the Series A Preferred Stock and/or the Series B Preferred Stock.



|7.7 | Transactions with Affiliates.
|--- | -----------------------------



Directly or indirectly enter into or permit to exist any material transaction with any Affiliate of Borrower except for transactions that are in the
ordinary course of Borrowers business, upon fair and reasonable terms that are no less favorable to Borrower than would be obtained in an arms length transaction with a nonaffiliated Person.



|7.8 | Subordinated Debt.
|--- | ------------------



Make or permit any payment on any Subordinated Debt, except under the terms of the Subordinated Debt, or amend any provision in any document relating to
the Subordinated Debt without Banks prior written consent.



|7.9 | Compliance.
|--- | -----------



Become an investment company or a company controlled by an investment company, under the Investment Company Act of 1940 or
undertake as one of its important activities extending credit to purchase or carry margin stock, or use the proceeds of any Credit Extension for that purpose; fail to meet the minimum funding requirements of ERISA, permit a Reportable Event or
Prohibited Transaction, as defined in ERISA, to occur; fail to comply with the Federal Fair Labor Standards Act or violate any other law or regulation, if the violation could reasonably be expected to have a material adverse effect on
Borrowers business or operations or would reasonably be expected to cause a Material Adverse Change, or permit any of its Subsidiaries to do so.



|8 | EVENTS OF DEFAULT
|- | -----------------



Any one of the following is an Event of Default:



|8.1 | Payment Default.
|--- | ----------------



If Borrower fails to pay any of the Obligations within 3 days after their due date, however, during such period no Credit Extensions will be made;



11



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|8.2 | Covenant Default.
|--- | -----------------



(a) If Borrower fails to perform any obligation under Sections 6.2 or 6.7 or violates any of the covenants contained in Section 7 of this Agreement, or



(b) If Borrower fails or neglects to perform, keep, or observe
any other material term, provision, condition, covenant, or agreement contained in this Agreement, in any of the Loan Documents, or in any other present or future agreement between Borrower and Bank and as to any default under such other term,
provision, condition, covenant or agreement that can be cured, has failed to cure such default within ten (10) days after the occurrence thereof; provided, however, that if the default cannot by its nature be cured within the ten (10) day period or
cannot after diligent attempts by Borrower be cured within such ten (10) day period, and such default is likely to be cured within a reasonable time, then Borrower shall have an additional reasonable period (which shall not in any case exceed thirty
(30) days) to attempt to cure such default, and within such reasonable time period the failure to have cured such default shall not be deemed an Event of Default (provided that no Credit Extensions will be made during such cure period);



|8.3 | Material Adverse Change.
|--- | ------------------------



If there (i) occurs a material adverse change in the business, operations, or financial condition of the Borrower, or (ii) is a material impairment of the
prospect of repayment of any portion of the Obligations; or (iii) is a material impairment of the value or priority of Banks security interests in the Collateral (the foregoing being defined as a Material Adverse Change).



|8.4 | Attachment.
|--- | -----------



If any material portion of Borrowers assets is attached, seized, levied on, or comes into possession of a trustee or receiver and the attachment,
seizure or levy is not removed in 10 days, or if Borrower is enjoined, restrained, or prevented by court order from conducting a material part of its business or if a judgment or other claim becomes a Lien on a material portion of Borrowers
assets, or if a notice of lien, levy, or assessment is filed against any of Borrowers assets by any government agency and not paid within 10 days after Borrower receives notice. These are not Events of Default if stayed or if a bond is posted
pending contest by Borrower (but no Credit Extensions will be made during the cure period);



|8.5 | Insolvency.
|--- | -----------



If Borrower becomes insolvent or if Borrower begins an Insolvency Proceeding or an Insolvency Proceeding is begun against Borrower and not dismissed or
stayed within 30 days (but no Credit Extensions will be made before any Insolvency Proceeding is dismissed);



|8.6 | Other Agreements.
|--- | -----------------



If there is a default in any agreement between Borrower and a third party that gives the third party the right to accelerate any Indebtedness exceeding
$100,000 or that could cause a Material Adverse Change;



|8.7 | Judgments.
|--- | ----------



If a money judgment(s) in the aggregate of at least $100,000 is rendered against Borrower and is unsatisfied and unstayed for 10 days (but no Credit
Extensions will be made before the judgment is stayed or satisfied); or



12



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|8.8 | Misrepresentations.
|--- | -------------------



If Borrower or any Person acting for Borrower makes any material misrepresentation or material misstatement now or later in any warranty or representation
in this Agreement or in any writing delivered to Bank or to induce Bank to enter this Agreement or any Loan Document.



|9 | BANKS RIGHTS AND REMEDIES
|- | --------------------------



|9.1 | Rights and Remedies.
|--- | --------------------



When an Event of Default occurs and continues Bank may, without notice or demand, do any or all of the following:



(a) Declare all Obligations immediately due and payable (but if an Event of
Default described in Section 8.5 occurs all Obligations are immediately due and payable without any action by Bank);



(b) Stop advancing money or extending credit for Borrowers benefit under this Agreement or under any other agreement between Borrower and Bank;



(c) Settle or adjust disputes and claims directly with account
debtors for amounts, on terms and in any order that Bank considers advisable; notify any Person owing Borrower money of Banks security interest in the funds and verify the amount of the Account. Borrower must collect all payments in trust for
Bank and, if requested by Bank, immediately deliver the payments to Bank in the form received from the account debtor, with proper endorsements for deposit;



(d) Make any payments and do any acts it considers necessary or reasonable to protect its security interest in the Collateral. Borrower will assemble the
Collateral if Bank requires and make it available as Bank designates. Bank may enter premises where the Collateral is located, take and maintain possession of any part of the Collateral, and pay, purchase, contest, or compromise any Lien which
appears to be prior or superior to its security interest and pay all expenses incurred. Borrower grants Bank a license to enter and occupy any of its premises, without charge, to exercise any of Banks rights or remedies;



(e) Apply to the Obligations any (i) balances and deposits of Borrower it
holds, or (ii) any amount held by Bank owing to or for the credit or the account of Borrower;



(f) Ship, reclaim, recover, store, finish, maintain, repair, prepare for sale, advertise for sale, and sell the Collateral; and



(g) Dispose of the Collateral according to the Code.



|9.2 | Power of Attorney.
|--- | ------------------



Effective only when an Event of Default occurs and continues, Borrower irrevocably appoints Bank as its lawful attorney to: (i) endorse Borrowers
name on any checks or other forms of payment or security; (ii) sign Borrowers name on any invoice or bill of lading for any Account or drafts against account debtors, (iii) make, settle, and adjust all claims under Borrowers insurance
policies; (iv) settle and adjust disputes and claims about the Accounts directly with account debtors, for amounts and on terms Bank determines reasonable; and (v) transfer the Collateral into the name of Bank or a third party as the Code permits.
Bank may exercise the power of attorney to sign Borrowers name on any documents necessary to perfect or continue the perfection of any security interest regardless of whether an Event of Default has occurred. Banks appointment as
Borrowers attorney in fact, and all of Banks rights and powers, coupled with an interest, are irrevocable until all Obligations have been fully repaid and performed and Banks obligation to provide Credit Extensions terminates.



13



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|9.3 | Bank Expenses.
|--- | --------------



If Borrower fails to pay any amount or furnish any required proof of payment to third persons, Bank may make all or part of the payment or obtain
insurance policies required in Section 6.5, and take any action under the policies Bank deems prudent. Any amounts paid by Bank are Bank Expenses and immediately due and payable, bearing interest at the then applicable rate and secured by the
Collateral. No payments by Bank are deemed an agreement to make similar payments in the future or Banks waiver of any Event of Default.



|9.4 | Banks Liability for Collateral.
|--- | --------------------------------



If Bank complies with reasonable banking practices and Section 9-207 of the Code, it is not liable for: (a) the safekeeping of the Collateral; (b) any
loss or damage to the Collateral; (c) any diminution in the value of the Collateral; or (d) any act or default of any carrier, warehouseman, bailee, or other person. Except as provided above, Borrower bears all risk of loss, damage or destruction of
the Collateral.



|9.5 | Remedies Cumulative.
|--- | --------------------



Banks rights and remedies under this Agreement, the Loan Documents, and all other agreements are cumulative. Bank has all rights and remedies
provided under the Code, by law, or in equity. Banks exercise of one right or remedy is not an election, and Banks waiver of any Event of Default is not a continuing waiver. Banks delay is not a waiver, election, or acquiescence.
No waiver is effective unless signed by Bank and then is only effective for the specific instance and purpose for which it was given.



|9.6 | Demand Waiver.
|--- | --------------



Borrower waives demand, notice of default or dishonor, notice of payment and nonpayment, notice of any default, nonpayment at maturity, release,
compromise, settlement, extension, or renewal of accounts, documents, instruments, chattel paper, and guarantees held by Bank on which Borrower is liable.



|10 | NOTICES
|-- | -------



All notices or demands by any party about this Agreement or any other related agreement must be in writing and be personally delivered or sent by an
overnight delivery service, by certified mail, postage prepaid, return receipt requested, or by telefacsimile to the addresses set forth at the beginning of this Agreement. A party may change its notice address by giving the other party written
notice.



|11 | CHOICE OF LAW, VENUE AND JURY TRIAL WAIVER
|-- | ------------------------------------------



California law governs the Loan Documents without regard to principles of conflicts of law. Borrower and Bank each submit to the exclusive jurisdiction of
the State and Federal courts in Santa Clara County, California.



BORROWER
AND BANK EACH WAIVE THEIR RIGHT TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION ARISING OUT OF ANY OF THE LOAN DOCUMENTS OR ANY CONTEMPLATED TRANSACTION, INCLUDING CONTRACT, TORT, BREACH OF DUTY AND ALL OTHER CLAIMS. THIS WAIVER IS A MATERIAL
INDUCEMENT FOR BOTH PARTIES TO ENTER INTO THIS AGREEMENT. EACH PARTY HAS REVIEWED THIS WAIVER WITH ITS COUNSEL.



14



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|12 | GENERAL PROVISIONS
|-- | ------------------



|12.1 | Successors and Assigns.
|---- | -----------------------



This Agreement binds and is for the benefit of the successors and permitted assigns of each party. Borrower may not assign this Agreement or any rights
under it without Banks prior written consent which may be granted or withheld in Banks discretion. Bank has the right, without the consent of or notice to Borrower, to sell, transfer, negotiate, or grant participation in all or any part
of, or any interest in, Banks obligations, rights and benefits under this Agreement.



|12.2 | Indemnification.
|---- | ----------------



Borrower will indemnify, defend and hold harmless Bank and its officers, employees, and agents against: (a) all obligations, demands, claims, and
liabilities asserted by any other party in connection with the transactions contemplated by the Loan Documents; and (b) all losses or Bank Expenses incurred, or paid by Bank from, following, or consequential to transactions between Bank and Borrower
(including reasonable attorneys fees and expenses), except for losses caused by Banks gross negligence or willful misconduct.



|12.3 | Time of Essence.
|---- | ----------------



Time is of the essence for the performance of all obligations in this Agreement.



|12.4 | Severability of Provision.
|---- | --------------------------



Each provision of this Agreement is severable from every other provision in determining the enforceability of any provision.



|12.5 | Amendments in Writing, Integration.
|---- | -----------------------------------



All amendments to this Agreement must be in writing and signed by Borrower and Bank. This Agreement represents the entire agreement about this subject
matter, and supersedes prior negotiations or agreements. All prior agreements, understandings, representations, warranties, and negotiations between the parties about the subject matter of this Agreement merge into this Agreement and the Loan
Documents.



|12.6 | Counterparts.
|---- | -------------



This Agreement may be executed in any number of counterparts and by different parties on separate counterparts, each of which, when executed and
delivered, are an original, and all taken together, constitute one Agreement.



|12.7 | Survival.
|---- | ---------



All covenants, representations and warranties made in this Agreement continue in full force while any Obligations remain outstanding. The obligations of
Borrower in Section 12.2 to indemnify Bank will survive until all statutes of limitations for actions that may be brought against Bank have run.



|12.8 | Confidentiality.
|---- | ----------------



In handling any confidential information, Bank will exercise the same degree of care that it exercises for its own proprietary information, but disclosure
of information may be made (i) to Banks subsidiaries or affiliates in connection with their business with Borrower, (ii) to prospective transferees or purchasers of any interest in the loans (provided, however, Bank shall use commercially
reasonable efforts in obtaining such prospective transferee or purchasers agreement of the terms of this provision), (iii) as required by law, regulation, subpoena, or other



15



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order, (iv) as required in connection with Banks examination or audit and (v) as Bank considers appropriate
exercising remedies under this Agreement. Confidential information does not include information that either: (a) is in the public domain or in Banks possession when disclosed to Bank, or becomes part of the public domain after disclosure to
Bank; or (b) is disclosed to Bank by a third party, if Bank does not know that the third party is prohibited from disclosing the information.



|12.9 | Effect of Amendment and Restatement.
|---- | ------------------------------------



This Agreement is intended to and does completely amend and restate, without novation, the Original Agreement. All credit extensions or loans outstanding
under the Original Agreement are and shall continue to be outstanding under this Agreement. All security interests granted under the Original Agreement are hereby confirmed and ratified and shall continue to secure all Obligations under this
Agreement.



|12.10 | Attorneys Fees, Costs and Expenses.
|----- | ------------------------------------



In any action or proceeding between Borrower and Bank arising out of the Loan Documents, the prevailing party will be entitled to recover its reasonable
attorneys fees and other reasonable costs and expenses incurred, in addition to any other relief to which it may be entitled.



|13 | DEFINITIONS
|-- | -----------



|13.1 | Definitions.
|---- | ------------



In this Agreement:



Accounts are all existing and later arising accounts, contract rights, and other obligations owed Borrower in connection with its sale
or lease of goods (including licensing software and other technology) or provision of services, all credit insurance, guaranties, other security and all merchandise returned or reclaimed by Borrower and Borrowers Books relating to any of the
foregoing, as such definition may be amended from time to time according to the Code.



Advance or Advances is a loan advance (or advances) under the Committed Revolving Line.



Affiliate of a Person is a Person that owns or controls directly or indirectly the Person, any Person that controls or is controlled by
or is under common control with the Person, and each of that Persons senior executive officers, directors, partners and, for any Person that is a limited liability company, that Persons managers and members.



Bank Expenses are all audit fees and expenses and
reasonable costs and expenses (including reasonable attorneys fees and expenses) for preparing, negotiating, administering, defending and enforcing the Loan Documents (including appeals or Insolvency Proceedings).



Borrowers Books are all Borrowers books and
records including ledgers, records regarding Borrowers assets or liabilities, the Collateral, business operations or financial condition and all computer programs or discs or any equipment containing the information.



Borrowing Base is 80% of Eligible Accounts as determined
by Bank from Borrowers most recent Borrowing Base Certificate; provided, however, that Bank may lower the percentage of the Borrowing Base after performing an audit of Borrowers Collateral.



Business Day is any day that is not a Saturday, Sunday or
a day on which the Bank is closed.



16



---

Code is the California Uniform Commercial Code, as applicable.



Collateral is the property described on Exhibit A.



Committed Revolving Line is an Advance of
up to $3,000,000.



Contingent Obligation is,
for any Person, any direct or indirect liability, contingent or not, of that Person for (i) any indebtedness, lease, dividend, letter of credit or other obligation of another such as an obligation directly or indirectly guaranteed, endorsed,
co-made, discounted or sold with recourse by that Person, or for which that Person is directly or indirectly liable; (ii) any obligations for undrawn letters of credit for the account of that Person; and (iii) all obligations from any interest rate,
currency or commodity swap agreement, interest rate cap or collar agreement, or other agreement or arrangement designated to protect a Person against fluctuation in interest rates, currency exchange rates or commodity prices; but Contingent
Obligation does not include endorsements in the ordinary course of business. The amount of a Contingent Obligation is the stated or determined amount of the primary obligation for which the Contingent Obligation is made or, if not
determinable, the maximum reasonably anticipated liability for it determined by the Person in good faith; but the amount may not exceed the maximum of the obligations under the guarantee or other support arrangement.



Credit Extension is each Advance, Term Loan, or any other
extension of credit by Bank for Borrowers benefit.



Current Liabilities are the aggregate amount of Borrowers Total Liabilities which mature within one (1) year plus Banks outstanding Obligations.



Deferred Revenue is all amounts received in advance of performance and not yet recognized as revenue.



Effective Date is the date Bank executes
this Agreement.



Eligible Accounts are
Accounts in the ordinary course of Borrowers business that meet all Borrowers representations and warranties in Section 5; but Bank may change eligibility standards by giving Borrower notice. Unless Bank agrees otherwise in
writing, Eligible Accounts will not include:



(a) Accounts
that the account debtor has not paid within 90 days of invoice date;



(b) Accounts for an account debtor, 50% or more of whose Accounts have not been paid within 90 days of invoice date;



(c) Credit balances over 90 days from invoice date;



(d) Accounts for an account debtor, including Affiliates, whose total obligations to Borrower exceed 25% of all Accounts, for the amounts that exceed that
percentage, unless the Bank approves in writing;



(e) Accounts
for which the account debtor does not have its principal place of business in the United States;



(f) Accounts for which the account debtor is a federal, state or local government entity or any department, agency, or instrumentality;



(g) Accounts for which Borrower owes the account debtor, but only up to the
amount owed (sometimes called contra accounts, accounts payable, customer deposits or credit accounts);



17



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(h) Accounts for demonstration or promotional equipment, or in which goods are consigned, sales
guaranteed, sale or return, sale on approval, bill and hold, or other terms if account debtors payment may be conditional;



(i) Accounts for which the account debtor is Borrowers Affiliate, officer, employee, or agent;



(j) Accounts in which the account debtor disputes liability or makes any
claim and Bank believes there may be a basis for dispute (but only up to the disputed or claimed amount), or if the Account Debtor is subject to an Insolvency Proceeding, or becomes insolvent, or goes out of business;



(k) Accounts for which Bank reasonably determines collection to be
doubtful.



Equipment is all present and
future machinery, equipment, tenant improvements, furniture, fixtures, vehicles, tools, parts and attachments in which Borrower has any interest.



ERISA is the Employment Retirement Income Security Act of 1974, and its regulations.



GAAP is generally accepted accounting principles.



Indebtedness is (a) indebtedness for
borrowed money or the deferred price of property or services, such as reimbursement and other obligations for surety bonds and letters of credit, (b) obligations evidenced by notes, bonds, debentures or similar instruments, (c) capital lease
obligations and (d) Contingent Obligations.



Insolvency Proceeding are proceedings by or against any Person under the United States Bankruptcy Code, or any other bankruptcy or insolvency law, including assignments for the benefit of creditors, compositions,
extensions generally with its creditors, or proceedings seeking reorganization, arrangement, or other relief.



Inventory is present and future inventory in which Borrower has any interest, including merchandise, raw materials, parts, supplies,
packing and shipping materials, work in process and finished products intended for sale or lease or to be furnished under a contract of service, of every kind and description now or later owned by or in the custody or possession, actual or
constructive, of Borrower, including inventory temporarily out of its custody or possession or in transit and including returns on any accounts or other proceeds (including insurance proceeds) from the sale or disposition of any of the foregoing and
any documents of title.



Investment is any
beneficial ownership of (including stock, partnership interest or other securities) any Person, or any loan, advance or capital contribution to any Person.



Lien is a mortgage, lien, deed of trust, charge, pledge, security interest or other encumbrance.



Loan Documents are, collectively, this Agreement, any
note, or notes or guaranties executed by Borrower or Guarantor, and any other present or future agreement between Borrower and/or for the benefit of Bank in connection with this Agreement, all as amended, extended or restated.



Material Adverse Change is defined in Section 8.3.



Obligations are debts, principal, interest,
Bank Expenses and other amounts Borrower owes Bank now or later, including cash management services, letters of credit and foreign



18



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exchange contracts, if any and including interest accruing after Insolvency Proceedings begin and debts, liabilities, or
obligations of Borrower assigned to Bank.



Original
Agreement has the meaning set forth in recital paragraph A.



Permitted Indebtedness is:



(a)
Borrowers indebtedness to Bank under this Agreement or any other Loan Document;



(b) Indebtedness existing on the Effective Date and shown on the Schedule;



(c) Subordinated Debt;



(d) Indebtedness to trade creditors incurred in the ordinary course of business; and



(e) Indebtedness secured by Permitted Liens.



Permitted Investments are:



(a) Investments shown on the Schedule and existing on the Effective Date; and



(b) (i) marketable direct obligations issued or unconditionally guaranteed
by the United States or its agency or any State maturing within 1 year from its acquisition, (ii) commercial paper maturing no more than 1 year after its creation and having the highest rating from either Standard & Poors Corporation or
Moodys Investors Service, Inc., and (iii) Banks certificates of deposit issued maturing no more than 1 year after issue.



Permitted Liens are:



(a) Liens existing on the Effective Date and shown on the Schedule or arising under this Agreement or other Loan Documents;



(b) Liens for taxes, fees, assessments or other government charges or
levies, either not delinquent or being contested in good faith and for which Borrower maintains adequate reserves on its Books, if they have no priority over any of Banks security interests;



(c) Purchase money Liens (i) on Equipment acquired or held by Borrower or
its Subsidiaries incurred for financing the acquisition of the Equipment, or (ii) existing on equipment when acquired, if the Lien is confined to the property and improvements and the proceeds of the equipment;



(d) Licenses or sublicenses granted in the ordinary course of
Borrowers business and any interest or title of a licensor or under any license or sublicense, if the licenses and sublicenses permit granting Bank a security interest;



(e) Leases or subleases granted in the ordinary course of Borrowers business, including in connection with
Borrowers leased premises or leased property;



(f) Liens
incurred in the extension, renewal or refinancing of the indebtedness secured by Liens described in (a) through (c), but any extension, renewal or replacement Lien must be limited to the property encumbered by the existing Lien and the
principal amount of the indebtedness may not increase.



Person is any individual, sole proprietorship, partnership, limited liability company, joint venture, company association, trust, unincorporated organization, association, corporation,



19



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institution, public benefit corporation, firm, joint stock company, estate, entity or government agency.



Prime Rate is Banks most recently announced
prime rate, even if it is not Banks lowest rate.



ResponsibleOfficer is each of the Chief Executive Officer, the President, the Chief Financial Officer and the Controller of Borrower.



Revolving Maturity Date is May 26, 2005.



Rights, as applied to the Collateral, means the Borrowers rights and interests in, and powers with
respect to, that Collateral, whatever the nature of those rights, interests and powers and, in any event, including Borrowers power to transfer rights in such Collateral to Bank.



Schedule is any attached schedule of exceptions.



Subordinated Debt is debt incurred by Borrower
subordinated to Borrowers indebtedness owed to Bank and which is reflected in a written agreement in a manner and form acceptable to Bank and approved by Bank in writing.



Subsidiary is for any Person, or any other business entity of which more than 50% of the voting stock or
other equity interests is owned or controlled, directly or indirectly, by the Person or one or more Affiliates of the Person.



Tangible Net Worth is, on any date, the consolidated total assets of Borrower and its Subsidiaries minus, (i) any amounts
attributable to (a) goodwill, (b) intangible items such as unamortized debt discount and expense, patents, trade and service marks and names, copyrights and research and development expenses except prepaid expenses, and (c) reserves not already
deducted from assets, and (ii) Total Liabilities.



Term Loan a loan of $1,822,900.



Term Loan Maturity Date is June 1, 2006.



TotalLiabilities is on any day, obligations that should, under GAAP, be classified as liabilities on Borrowers consolidated balance sheet, including all Indebtedness, and current portion Subordinated Debt
allowed to be paid, but excluding all other Subordinated Debt.



BORROWER:



Pharsight Corporation



|       |  |                             
|------ |  | ----------------------------
|By:    |  | /s/ Cynthia Stephens 5-24-04
|Title: |  | SVP & CFO                   



20



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BANK:



SILICON VALLEY BANK



|                |  |                
|--------------- |  | ---------------
|By:             |  | /s/ Ron Kundich
|Title:          |  | VP             
|Effective Date: |  | 5-27-04        



21



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EXHIBIT A



The Collateral consists of all of Borrowers right, title and interest in and to the following whether owned now or hereafter arising and whether
the Borrower has rights now or hereafter has rights therein and wherever located:



All goods and equipment now owned or hereafter acquired, including, without limitation, all machinery, fixtures, vehicles (including motor vehicles and trailers), and any interest in any of the foregoing, and all
attachments, accessories, accessions, replacements, substitutions, additions, and improvements to any of the foregoing, wherever located;



All inventory, now owned or hereafter acquired, including, without limitation, all merchandise, raw materials, parts, supplies, packing and shipping
materials, work in process and finished products including such inventory as is temporarily out of Borrowers custody or possession or in transit and including any returns upon any accounts or other proceeds, including insurance proceeds,
resulting from the sale or disposition of any of the foregoing and any documents of title representing any of the above;



All contract rights and general intangibles (as such definitions may be amended from time to time according to the Code), now owned or hereafter acquired,
including, without limitation, goodwill, trademarks, servicemarks, trade styles, trade names, patents, patent applications, leases, license agreements, franchise agreements, blueprints, drawings, purchase orders, customer lists, route lists,
infringements, claims, computer programs, computer discs, computer tapes, literature, reports, catalogs, design rights, income tax refunds, payments of insurance and rights to payment of any kind,;



All now existing and hereafter arising accounts, contract rights, royalties,
license rights and all other forms of obligations owing to Borrower arising out of the sale or lease of goods, the licensing of technology or the rendering of services by Borrower (as such definitions may be amended from time to time according to
the Code) whether or not earned by performance, and any and all credit insurance, insurance (including refund) claims and proceeds, guaranties, and other security therefor, as well as all merchandise returned to or reclaimed by Borrower;



All documents, cash, deposit accounts, securities, securities
entitlements, securities accounts, investment property, financial assets, letters of credit, letter of credit rights, certificates of deposit, instruments and chattel paper and electronic chattel paper now owned or hereafter acquired and
Borrowers Books relating to the foregoing;



All copyright
rights, copyright applications, copyright registrations and like protections in each work of authorship and derivative work thereof, whether published or unpublished, now owned or hereafter acquired; all trade secret rights, including all rights to
unpatented inventions, know-how, operating manuals, license rights and agreements and confidential information, now owned or hereafter acquired; all mask work or similar rights available for the protection of semiconductor chips, now owned or
hereafter acquired; all claims for damages by way of any past, present and future infringement of any of the foregoing; and



All Borrowers Books relating to the foregoing and any and all claims, rights and interests in any of the above and all substitutions for, additions
and accessions to and proceeds thereof.



Borrower and Bank are
parties to that certain Negative Pledge Agreement, whereby Borrower, in connection with Banks loan or loans to Borrower, has agreed, among other things, not to sell, transfer, assign, mortgage, pledge, lease grant a security interest in, or
encumber any of its intellectual property, without Banks prior written consent.



Notwithstanding the foregoing, the Collateral shall not be deemed to include any copyrights, copyright applications, copyright registration and like protection in each work of authorship and derivative work thereof,
whether published or unpublished, now owned or hereafter acquired; any patents, patent applications and like protections including without limitation improvements, divisions, continuations, renewals, reissues, extensions and continuations-in-part of
the same, trademarks, servicemarks and applications therefor, whether registered or not, and the goodwill of the business of Borrower connected with and symbolized by such trademarks, any trade



---

secret rights, including any rights to unpatented inventions, know-how, operating manuals, license rights and agreements
and confidential information, now owned or hereafter acquired; or any claims for damage by way of any past, present and future infringement of any of the foregoing (collectively, the Intellectual Property), except that the Collateral
shall include the proceeds of all the Intellectual Property including proceeds from the sale, licensing or other disposition of the Intellectual Property and proceeds that are accounts, (e.g., accounts receivable of Borrower, or general intangibles
consisting of proceeds and rights to payment). Notwithstanding the prior sentence, if a judicial authority (including a U.S. Bankruptcy Court) holds that a security interest in the underlying Intellectual Property is necessary to have a security
interest in such accounts and general intangibles of Borrower that are proceeds of the Intellectual Property, then the Collateral shall automatically, and effective as of the Effective Date, include the Intellectual Property to the extent necessary
to permit perfection of Banks security interest in such accounts and general intangibles of Borrower that are proceeds of the Intellectual Property.



2



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EXHIBIT B



LOAN PAYMENT/ADVANCE REQUEST FORM

DEADLINE FOR SAME DAY PROCESSING IS 12:00 P.S.T.

|        |  |      
|------- |  | -----
|Fax To: |  | Date:



| ̈ | LOAN PAYMENT:
|- | -------------



Pharsight Corporation (Borrower)



|                              |  |                 
|----------------------------- |  | ----------------
|From Account
#                |  | To Account
#    
|(Deposit Account
#)           |  | (Loan Account #)
|                             
|Principal
$ and/or Interest
$



All Borrowers
representation and warranties in the Loan and Security Agreement are true, correct and complete in all material respects up to and including the date of the transfer request for a loan payment, but those representations and warranties expressly
referring to another date shall be true, correct and complete in all material respects as of that date:



|                      |  |               |  |                           
|--------------------- |  | ------------- |  | --------------------------
|Authorized Signature: |  | Phone Number: |  | __________________________



| ̈ | LOAN ADVANCE:
|- | -------------



CompleteOutgoing Wire Requestsection below if all or a portion of the funds from this loan advance are for an outgoing wire.



|                 |  |                    
|---------------- |  | -------------------
|From Account
#   |  | To Account
#       
|(Loan Account
#) |  | (Deposit Account
#)



Amount of Advance
$



All Borrowers representation and warranties in the
Amended and Restated Loan and Security Agreement are true, correct and complete in all material respects up to and including the date of the transfer request for an advance, but those representations and warranties expressly referring to another
date shall be true, correct and complete in all material respects as of that date:



|                      |  |               |  |                           
|--------------------- |  | ------------- |  | --------------------------
|Authorized Signature: |  | Phone Number: |  | __________________________



OUTGOING WIRE REQUEST



Complete only if all or a portion of funds from theloan advanceabove are to be wired.



Deadline for same day processing is 12:00pm, P.S.T.



|                  |  |                  
|----------------- |  | -----------------
|Beneficiary Name: |  | Amount of Wire:
$
|Beneficiary Bank: |  | Account Number:  
|City and State:   |  |                  



Beneficiary Bank
Transit (ABA) #: 
Beneficiary Bank Code (Swift, Sort, Chip, etc.):

(For International Wire Only)



|                   |  |                 
|------------------ |  | ----------------
|Intermediary Bank: |  | Transit (ABA) #:



For Further Credit
to:



Special Instruction:



By signing below, I (we) acknowledge and agree that my (our) funds transfer
request shall be processed in accordance with and subject to the terms and conditions set forth in the agreements(s) covering funds transfer service(s), which agreements(s) were previously received and executed by me (us).



|                      |  |                            
|--------------------- |  | ---------------------------
|Authorized Signature: |  | 2ndSignature (If Required):
|Print Name/Title:     |  | Print Name/Title:          
|Telephone #           |  | Telephone #                



---

Schedule to Loan and Security Agreement



|                                                                                                                                                                                      |  | 
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | 
|The exact correct corporate name of Borrower is (attach a copy of the formation documents, e.g., articles, partnership agreement):                                                    |  | 
|                                                                                                                                                                                      | 
|Borrowers State of formation:                                                                                                                                                        |  | 
|                                                                                                                                                                                      | 
|Borrower has operated under only the following other names (if none, so state):                                                                                                       |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                     
|All other address at which the Borrower does business are as follows (attach additional sheets if necessary and include all warehouse addresses):                                    
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      | 
|Borrower has deposit accounts and/or investment accounts located only at the following institutions:                                                                                  |  | 
|                                                                                                                                                                                      |  | 
|List Acct.
Numbers:                                                                                                                                                                   |  | 
|                                                                                                                                                                                      | 
|Liens existing on the Effective Date and disclosed to and accepted by Bank in writing:                                                                                                |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      | 
|Investments existing on the Effective Date and disclosed to and accepted by Bank in writing:                                                                                          |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      | 
|Subordinated Debt:                                                                                                                                                                    |  | 
|                                                                                                                                                                                      | 
|Indebtedness on the Effective Date and disclosed to and consented to by Bank in writing:                                                                                              |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      |  | 
|                                                                                                                                                                                      |  | 
|Borrower is not subject to litigation which would have a material adverse effect on the Borrowers financial condition, except the following (attach additional comments, if
needed): |  | 
|                                                                                                                                                                                     
|                                                                                                                                                                                     
|                                                                                                                                                                                      | 
|Tax ID Number                                                                                                                                                                         |  | 
|                                                                                                                                                                                      | 
|Organizational Number, if
any:                                                                                                                                                        |  | 















2



---

EXHIBIT C

BORROWING BASE CERTIFICATE



|                                |  |       |  |                      
|------------------------------- |  | ----- |  | ---------------------
|Borrower: Pharsight Corporation |  | Bank: |  | Silicon Valley Bank  
|                                |  |       |  | 3003 Tasman Drive    
|                                |  |       |  | Santa Clara, CA 95054
|Commitment Amount: $3,000,000   |  |       |  |                      



|                                                     |  |                                              |  |   |  |  |   | 
|---------------------------------------------------- |  | -------------------------------------------- |  | - |  |  | - | 
|ACCOUNTS RECEIVABLE                                  |  |                                              |  |   |  | 
|1.                                                   |  | Accounts Receivable Book Value as of         |  |   |  |  | $ | 
|2.                                                   |  | Additions (please explain on reverse)        |  |   |  |  | $ | 
|3.                                                   |  | TOTAL ACCOUNTS RECEIVABLE                    |  |   |  |  | $ | 
|                                                     |  |                                             
|ACCOUNTS RECEIVABLE DEDUCTIONS (without duplication) |  |                                              |  |   |  | 
|4.                                                   |  | Amounts over 90 days due                     |  | $ |  |  |   | 
|5.                                                   |  | Balance of 50% over 90 day accounts          |  | $ |  |  |   | 
|6.                                                   |  | Credit balances over 90 days                 |  | $ |  |  |   | 
|7.                                                   |  | Concentration Limits                         |  | $ |  |  |   | 
|8.                                                   |  | Foreign Accounts                             |  | $ |  |  |   | 
|9.                                                   |  | Governmental Accounts                        |  | $ |  |  |   | 
|10.                                                  |  | Contra Accounts                              |  | $ |  |  |   | 
|11.                                                  |  | Promotion or Demo Accounts                   |  | $ |  |  |   | 
|12.                                                  |  | Intercompany/Employee Accounts               |  | $ |  |  |   | 
|13.                                                  |  | Other (please explain on reverse)            |  | $ |  |  |   | 
|14.                                                  |  | TOTAL ACCOUNTS RECEIVABLE DEDUCTIONS         |  |   |  |  | $ | 
|15.                                                  |  | Eligible Accounts (#3 minus #14 )            |  |   |  |  | $ | 
|16.                                                  |  | LOAN VALUE OF ACCOUNTS (80% of #15)          |  |   |  |  | $ | 
|                                                     |  |                                             
|BALANCES                                             |  |                                              |  |   |  | 
|17.                                                  |  | Maximum Loan Amount                          |  | $ |  |  |   | 
|18.                                                  |  | Total Funds Available [Lesser of #17 or #16] |  |   |  |  | $ | 
|19.                                                  |  | Present balance owing on Line of Credit      |  | $ |  |  |   | 
|20.                                                  |  | Outstanding under Sublimits (none)           |  | $ |  |  |   | 
|21.                                                  |  | RESERVE POSITION (#18 minus #19 and #20)     |  |   |  |  | $ | 



The undersigned represents and
warrants that this is true, complete and correct, and that the information in this Borrowing Base Certificate complies with the representations and warranties in the Amended and Restated Loan and Security Agreement between the undersigned and
Silicon Valley Bank.



COMMENTS:



|                      |  |                  
|--------------------- |  | -----------------
|Pharsight Corporation
|                      | 
|By:                   |  |                  
|                      |  | Authorized Signer



|             
|-------------
|BANK USE ONLY
|             
|Recd By:    
|Auth. Signer 
|             
|Date:        
|             
|Verified:    
|Auth. Signer 
|             
|Date:        
|             
|             



---

EXHIBIT D

COMPLIANCE CERTIFICATE



|      |  |                      
|----- |  | ---------------------
|TO:   |  | SILICON VALLEY BANK  
|      |  | 3003 Tasman Drive    
|      |  | Santa Clara, CA 95054
|      | 
|FROM: |  | PHARSIGHT CORPORATION



The undersigned
Responsible Officer of Pharsight Corporation (Borrower) certifies that under the terms and conditions of the Amended and Restated Loan and Security Agreement between Borrower and Bank (the Agreement), (i) Borrower is in
complete compliance for the period ending  with all required covenants
except as noted below and (ii) all representations and warranties in the Agreement are true and correct in all material respects on this date. In addition, the undersigned certifies that Borrower, and each Subsidiary, has timely filed all required
tax returns and paid, or made adequate provision to pay, all material taxes, except those being contested in good faith with adequate reserves under GAAP. Attached are the required documents supporting the certification. The Officer certifies that
these are prepared in accordance with Generally Accepted Accounting Principles (GAAP) consistently applied from one period to the next except as explained in an accompanying letter or footnotes. The Responsible Officer acknowledges that no
borrowings may be requested at any time or date of determination that Borrower is not in compliance with any of the terms of the Agreement, and that compliance is determined not just at the date this certificate is delivered.



Please indicate compliance status by circling Yes/No under
Complies column.



|                                             |  |                                         |  |          |  |   
|-------------------------------------------- |  | --------------------------------------- |  | -------- |  | --
|Reporting Covenant                           |  | Required                                |  | Complies
|Monthly financial statements + CC            |  | Monthly within 30 days                  |  | Yes      |  | No
|Annual (Audited)                             |  | FYE within 5 days after filing with SEC |  | Yes      |  | No
|A/R & A/P Agings, deferred revenue schedules |  | Monthly within 20 days                  |  | Yes      |  | No
|A/R Audit                                    |  | Semi-Annual                             |  | Yes      |  | No
|Borrowing Base Certificate                   |  | Monthly within 20 days                  |  | Yes      |  | No
|Board of Directors approved operating plan   |  | Annually by April 30th                  |  | Yes      |  | No



|                                                                                     |  |          |      |    |        |       |          |     |  |   
|------------------------------------------------------------------------------------ |  | -------- | ---- | -- | ------ | ----- | -------- | --- |  | --
|Financial Covenant                                                                   |  | Required |      |    | Actual |       | Complies
|Maintain on a Monthly Basis (unless otherwise noted): Minimum Quick Ratio (Adjusted) |  |          | *    |    |        | :1.00 |          | Yes |  | No
|Profitability (Quarterly)                                                            |  | $        | 1.00 | ** |        |       |          | Yes |  | No

---

|* | A ratio of cash and cash equivalents plus accounts receivables divided by Current Liabilities minus Deferred Revenue of at least (i) 1.50 to 1.00 for the months ending April 30,
2004; May 31, 2004, June 30, 2004 and July 31, 2004; (ii) 1.75 to 1.00 for the months ending August 31, 2004, September 30, 2004, October 31, 2004 and November 30, 2004 and (iii) 2.00 to 1.00 for the months ending December 31, 2004 and thereafter.
|- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|** | Borrower may suffer a loss not to exceed $500,000 for quarter ending June 30, 2004.
|-- | -----------------------------------------------------------------------------------



Borrower only has deposit accounts located at the following
institutions:.



---

|                                            
|--------------------------------------------
|Comments Regarding Exceptions: See Attached.
|                                            
|Sincerely,                                  
|                                            
|Pharsight Corporation                       
|                                            
|SIGNATURE                                   
|                                            
|TITLE                                       
|                                            
|DATE                                        



|                                                                 
|-----------------------------------------------------------------
|BANK USE ONLY                                                    
|                                                                 
|Received by:                                                     
|AUTHORIZED SIGNER                                                
|                                                                 
|Date:                                                            
|                                                                 
|Verified:                                                        
|AUTHORIZED SIGNER                                                
|                                                                 
|Date:                                                            
|                                                                 
|Compliance Status:
                                Yes       
 No



2



---

LOGO



SILICON VALLEY BANK



PRO FORMA INVOICE FOR LOAN CHARGES



|              |  |                          |  |   |            |  
|------------- |  | ------------------------ |  | - | ---------- | -
|BORROWER:     |  | Pharsight Corporation    |  |   |           
|              |  |                         
|LOAN OFFICER: |  | Ron Kundich              |  |   |           
|              |  |                         
|DATE:         |  | May 17, 2004             |  |   |           
|              |  |                         
|              |  | Revolving Loan Fee       |  | $ | 10,500.00  |  
|              |  | Credit Report            |  |   | 35.00      |  
|              |  | UCC Search Fee           |  |   | 300.00     |  
|              |  | UCC Filing Fee           |  |   | 100.00     |  
|              |  | Documentation Fee        |  |   | 1,500.00   |  
|              |  |                         
|              |  | Less Good Faith Deposit: |  |   | (10,000.00 | )
|              |  |                         
|              |  | TOTAL FEE DUE            |  | $ | 2,435.00   |  
|              |  |                          |  |   |            |  



Please indicate the method of
payment:



| | {    } | A check for the total amount is attached.
| | ------ | -----------------------------------------



| | {    } | Debit DDA #  for the total amount.
| | ------ | ----------------------------------



| | {    } | Loan proceeds
| | ------ | -------------



|          |  |                    
|--------- |  | -------------------
|Borrower:
|          | 
|By:       |  |                    
|          |  | (Authorized Signer)



|                            |  |       
|--------------------------- |  | ------
|Silicon Valley Bank         |  | (Date)
|                           
|Account Officers Signature



---

CORPORATE BORROWING RESOLUTION



|          |  |                                    |  |       |  |                           
|--------- |  | ---------------------------------- |  | ----- |  | --------------------------
|Borrower: |  | Pharsight Corporation              |  | Bank: |  | Silicon Valley Bank       
|          |  | 800 West El Camino Real, Suite 200 |  |       |  | 3003 Tasman Drive         
|          |  | Mountain View, CA 94040            |  |       |  | Santa Clara, CA 95054-1191



I, the Secretary or Assistant
Secretary of Pharsight Corporation (Borrower), CERTIFY that Borrower is a corporation existing under the laws of the State of Delaware.



Icertify that at a meeting of Borrowers Directors (or by other authorized corporate action) duly held the following resolutions were adopted.



It is resolved that any oneof the following officers of Borrower, whose name, title
and signature is below:



|                 |  |           |  |                     
|---------------- |  | --------- |  | --------------------
|NAMES            |  | POSITIONS |  | ACTUAL SIGNATURES   
|Cynthia Stephens |  | SVP & CFO |  | /s/ Cynthia Stephens
|                 |  |           |  |                     
|                 |  |           |  |                     
|                 |  |           |  |                     



may act for Borrower and:



Borrow Money. Borrow money from Silicon Valley
Bank (Bank).



Execute Loan
Documents. Execute any loan documents Bank requires.



Grant Security. Grant Bank a security interest in any of Borrowers assets.



Negotiate Items. Negotiate or discount all drafts, trade acceptances, promissory notes, or other indebtedness in which Borrower has an interest and
receive cash or otherwise use the proceeds.



Letters of Credit. Apply for letters of credit from Bank.



Foreign Exchange Contracts. Execute spot or forward foreign exchange contracts.



Issue Warrants. Issue warrants for Borrowers stock.



Further Acts. Designate other individuals to request advances, pay fees and costs and execute other documents or
agreements (including documents or agreement that waive Borrowers right to a jury trial) they think necessary to effectuate these Resolutions.



Further resolved that all acts authorized by these Resolutions and performed before they were adopted are ratified. These Resolutions remain in effect and Bank may
rely on them until Bank receives written notice of their revocation.



Icertify that the persons listed above are Borrowers officers with the titles and signatures shown following their names and that these resolutions have not been modified are currently effective.



---

CERTIFIED TO AND ATTESTED BY:



|                                  |  |                     
|--------------------------------- |  | --------------------
|X                                 |  | /s/ Cynthia Stephens
|*Secretary or Assistant Secretary
|                                  | 
|X                                 |  | /s/ Shawn OConnor  

---

|* | NOTE: In case the Secretary or other certifying officer is designated by the foregoing resolutions as one of the signing officers, this resolution should also be signed by a second
Officer or Director of Borrower.
|- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



2



---

Exhibit F



NEGATIVE PLEDGE AGREEMENT



This Negative Pledge Agreement is made as of the Effective Date by and between Pharsight Corporation (Borrower) and Silicon Valley Bank (Bank).



In connection with, among other documents, the Amended and Restated Loan and
Security Agreement (the Loan Documents) being concurrently executed herewith between Borrower and Bank, Borrower agrees as follows:



| | 1. | Except for non-exclusive licenses granted in the ordinary course of business, Borrower shall not sell, transfer, assign, mortgage, pledge, lease, grant a security interest in, or
encumber any of Borrowers intellectual property, including, without limitation, the following:
| | -- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | a. | Any and all copyright rights, copyright applications, copyright registrations and like protections in each work or authorship and derivative work thereof, whether published or
unpublished and whether or not the same also constitutes a trade secret, now or hereafter existing, created, acquired or held;
| | -- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | b. | All mask works or similar rights available for the protection of semiconductor chips, now owned or hereafter acquired;
| | -- | ----------------------------------------------------------------------------------------------------------------------



| | c. | Any and all trade secrets, and any and all intellectual property rights in computer software and computer software products now or hereafter existing, created, acquired or held;
| | -- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | d. | Any and all design rights which may be available to Borrower now or hereafter existing, created, acquired or held;
| | -- | ------------------------------------------------------------------------------------------------------------------



| | e. | All patents, patent applications and like protections including, without limitation, improvements, divisions, continuations, renewals, reissues, extensions and continuations-in-part
of the same, including without limitation the patents and patent applications;
| | -- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | f. | Any trademark and servicemark rights, whether registered or not, applications to register and registrations of the same and like protections, and the entire goodwill of the business
of Borrower connected with and symbolized by such trademarks;
| | -- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | g. | Any and all claims for damages by way of past, present and future infringements of any of the rights included above, with the right, but not the obligation, to sue for and collect
such damages for said use or infringement of the intellectual property rights identified above;
| | -- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | h. | All licenses or other rights to use any of the Copyrights, Patents, Trademarks or Mask Works, and all license fees and royalties arising from such use to the extent permitted by
such license or rights; and
| | -- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | i. | All amendments, extensions, renewals and extensions of any of the Copyrights, Trademarks, Patents, or Mask Works; and
| | -- | ---------------------------------------------------------------------------------------------------------------------



| | j. | All proceeds and products of the foregoing, including without limitation all payments under insurance or any indemnity or warranty payable in respect of any of the foregoing;
| | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



3



---

| | 2. | It shall be an event of default under the Loan Documents between Borrower and Bank if there is a breach of any term of this Negative Pledge Agreement.
| | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------



| | 3. | Capitalized terms used but not otherwise defined herein shall have the same meaning as in the Loan Documents.
| | -- | -------------------------------------------------------------------------------------------------------------



BORROWER:



Pharsight Corporation



|       |  |                                          |  | 
|------ |  | ---------------------------------------- |  | 
|By:    |  | /s/ Cynthia Stephens             5-24-04
|Title: |  | SVP & CFO                               



BANK:



SILICON VALLEY BANK



|       |  |                
|------ |  | ---------------
|By:    |  | /s/ Ron Kundich
|Name:  |  | Ron Kundich    
|Title: |  | VP