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Exhibit 4.07

SUBSCRIPTION AGREEMENT

THIS AGREEMENTdated for reference the 25 day of October,
2006.

BETWEEN:

ADVANCED PROTEOME THERAPEUTICS,
INC.

(APT)

AND:

ADVANCED PROTEOME THERAPEUTICS
CORP.

(APT Canada)

WHEREAS:

(A)    By way of a letter of intent dated May 25,
2006 Thrilltime Entertainment International Inc. (Thrilltime) was granted the
right to subscribe for 48,007,297 shares of the Class A Common Stock, par value
$.00001, of APT (the APT Shares) for total consideration of CAD$2,000,000;

(B)    As a condition of the completion of that
transaction it was contemplated that the shareholders of Thrilltime, by way of a
plan of arrangement (the Plan of Arrangement), would exchange their shares for
shares of a newly incorporated company to be listed on the TSX Venture
Exchange;

(C)    Pursuant to an arrangement agreement dated
August 15, 2006 between Thrilltime and APT Canada, it was agreed to effect the
Plan of Arrangement by having shareholders of Thrilltime exchange their shares
for shares of APT Canada;

(D)    In anticipation of the completion of the
Plan of Arrangement the parties hereto have agreed to enter into this
Subscription Agreement to provide for the purchase of the APT Shares by APT
Canada;

NOW THEREFORE THIS AGREEMENT WITNESSES THAT for good and
valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, the parties hereto agree as follows:

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|1. | Subscription
|-- | ------------

1.1    Based and relying on the representations set
forth in Section 2 hereof, APT Canada hereby agrees to subscribe for the APT
Shares for the consideration set forth below and, on receipt of such
consideration, APT agrees to issue the APT Shares.

1.2    The total consideration to be paid for the
APT Shares shall be CAD$2,000,000, which payment shall be satisfied on the
Closing Date by the payment of such monies to APT by way of certified cheque or
wire transfer.

|2. | Representations and Warranties
|-- | ------------------------------

2.1    APT hereby represents and warrants to APT
Canada as follows and acknowledges that APT Canada is relying on these
representations and warranties in connection with the transactions completed
herein:

(a)    APT is valid
existing and in good standing under the laws of Delaware and has the corporate
power and authority to own its assets and to carry on its business as currently
conducted and has the corporate power and authority to enter into this Agreement
and perform its obligations hereunder;

(b)    as of the date
hereof, the outstanding share capital of APT consists of 41,000,000 shares of
Class B Common Stock, par value $00001, all of which are owned by Allen Krantz
(Krantz), and there are no other rights, options or entitlements, other than
as contemplated herein, for the purchase or issue of any shares of APT;

(c)    the APT Shares, when
issued to APT Canada in accordance with the terms hereof; will be issued as
fully paid and non-assessable, free of any liens, charges, encumbrances or
pre-emptive rights;

(d)    this Agreement has
been duly executed and delivered by APT and constitutes a legal, valid and
binding obligation;

(e)    the execution and
delivery of this Agreement and the completion of the transactions contemplated
hereby do not and will not violate any provision of law or administrative
regulation to which APT is subject or constitute a breach of or a default under
any agreement to which APT is a party;

(f)    as at the Closing
Date APT will have secured all consents, approvals, orders and authorizations
required to be obtained in connection with the execution and delivery of this
Agreement and the consummation of the transactions contemplated hereby.

2.2    APT Canada hereby represents and warrants to
APT as follows and acknowledges that APT is relying on these representations and
warranties in connection with the transactions contemplated herein:

(a)    APT Canada is duly
organized and in good standing under the laws of the Province of British
Columbia and has the corporate power to own its assets and to carry

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on its business as currently conducted and
has the corporate power and authority to enter into this Agreement and perform
its obligations hereunder;

(b)    this Agreement has
been duly executed and delivered by APT Canada and constitutes a legal, valid
and binding obligation;

(c)    the execution and
delivery of this Agreement and the completion of the transactions contemplated
hereby do not and will not violate any provision of law or administrative
regulation to which APT Canada is subject or constitute a breach of or a default
under any agreement to which APT Canada is a party;

(d)    as at the Closing
Date APT Canada will have secured all consents, approvals, orders and
authorizations required to be obtained in connection with the execution and
delivery of this Agreement and the consummation of the transactions contemplated
hereby.

|3. | Issuance and Contribution of APT Canada Shares to APT
|-- | -----------------------------------------------------

3.1    In order to give effect to the redemption
rights possessed by holders of the Class B Common Stock of APT (the Class B
Shares) entitling the holder thereof to redeem the Class B Shares and acquire
from APT shares of APT Canada on a 1 for 1 basis, APT Canada hereby agrees to
grant to APT the right, but not the obligation, to acquire that number of shares
of APT Canada as needed to enable APT to satisfy its redemption obligations from
time to time with respect to the Class B Shares, and as consideration therefore
APT shall issue to APT Canada such number of shares of its Class A Common Stock
as is equal to the number of APT Canada shares acquired.

|4. | Subsequent Subscriptions
|-- | ------------------------

4.1    It is acknowledged that it is the intention
of the parties hereto that, subsequent to the issuance of the APT Shares
contemplated hereunder, the number of issued and outstanding shares of Class A
Common Stock of APT held by APT Canada shall at all times equal the number of
issued and outstanding common shares of APT Canada and in this regard it is
acknowledged and agreed that in each instance where APT Canada increases its
share capital by the issuance of further shares (the Further APT Canada
Shares), it shall apply any monies received in consideration for such share
issuances, less such amount as the board of directors of APT Canada, acting
reasonably, shall determine is appropriately retained to be applied to the
ongoing general and administrative expenses of APT Canada, on account of a
subscription for such number of shares of Class A Common Stock of APT (the
Further APT Shares) as shall equal the number of Further APT Canada Shares
issued; and the parties hereto shall take such steps as shall be necessary to
cause the Further APT Shares to be duly and validly issued to APT Canada.

4.2    Notwithstanding the above, in circumstances
where APT Canada shall issue Further APT Canada Shares for non-monetary
consideration, APT Canada shall then subscribe for nominal consideration for
such Further APT Shares as shall equal (he number of Further APT Canada Shares
then issued and the parties hereto shall take such steps as shall be necessary
to cause the Further APT Shares to be duly and validly issued to APT Canada.

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4.3    Notwithstanding the foregoing, this section
4 shall not apply to any issuance of shares of APT Canada to APT, pursuant to
Section 3, above, as a result of the exercise of a redemption right by a holder
of Class B Common Stock.

|5. | Conditions of Closing
|-- | ---------------------

5.1    Closing of the transaction contemplated
hereby is subject to:

(a)    completion of the
Plan of Arrangement;

(b)    confirmation, in
form satisfactory to APT, acting reasonably, that on closing of the transactions
contemplated hereby the shares of APT Canada will be listed and posted for
trading on the TSX Venture Exchange;

(c)    exercise by APT
Canada of the conversion rights granted under that loan agreement between APT
and Thrilltime dated May 25, 2006 (the Loan Agreement), as assigned to APT
Canada effective September 15, 2006, including advance of the balance of the
CDN$300,000 contemplated by the Loan Agreement, and issuance of 4,000,000 shares
of APT Class A Common Stock in exchange (the APT Loan Conversion Shares);

(d)    as of the Closing
Date APT Canada will have a minimum of CAD$2,100,000 of working capital
(calculated prior to the assumption of the costs of APT as contemplated by
Section 7(c) herein);

(e)    as at the Closing
Date APT Canada will have no more than 52,007,297 shares issued and
outstanding;

(f)    each of APT and APT
Canada shall have entered into employment agreements with Krantz on terms
acceptable to Krantz, acting reasonably, which employment agreements shall
provide for change of control provisions whereby Krantz would be entitled to
three years salary in circumstances where a change of control of APT Canada
were to occur, it being acknowledged that these provisions will expire in
circumstances where Krantz was to dispose of the shares of APT held by him;

(g)    all representations,
warranties, certifications, confirmations and other statements made in or
pursuant to this Subscription Agreement being accurate and complete in all
material respects on and as of the Closing Date;

(h)    there having been no
material adverse change in the affairs, prospects or financial status of APT
Canada or APT between the date of execution of this Subscription Agreement and
the Closing Date;

(i)    Krantz and APT
Canada shall have entered into an agreement which will provide that management
of APT Canada will take such steps as are required to ensure that the board of
APT Canada will consist of five members, three of which members shall be
nominees of Krantz; and

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(j)    Krantz and APT
Canada shall have entered into a shareholders agreement with respect to their
shareholdings in APT, which agreement shall include a right of first refusal in
favour of APT Canada in respect of Krantzs holdings in APT and provisions to
ensure that the shareholdings of APT Canada in APT will at all times equal the
then issued and outstanding share capital of APT Canada.

|6. | Closing
|-- | -------

6.1    Closing of the transactions contemplated
hereby shall take place on the effective date of the Plan of Arrangement (the
Closing Date) or such later date as the parties hereto may mutually agree to
in writing.

6.2    At Closing:

(a)    APT shall deliver
certificates representing the APT Shares and the APT Loan Conversion Shares, in
the aggregate amount of 52,007,297, registered in the name of APT Canada;
and

(b)    APT Canada shall pay
CAD$2,000,000 to APT for the APT Shares, by way of certified cheque or wire
transfer, and shall lend the balance of the CAN$300,000 contemplated by the Loan
Agreement and immediately thereafter assign and transfer of the related
promissory note to APT, in exchange for the APT Loan Conversion Shares.

|7. | Transaction Costs and Brokerage; Indemnity
|-- | ------------------------------------------

(a)    if the transactions
contemplated hereby are not completed because APT Canada decides for any reason
not to proceed with such transactions, APT Canada will be responsible for paying
all of APTs and Krantzs reasonable fees and any expenses incurred to such time
in connection with the transactions;

(b)    if the transactions
are not completed for any other reason, each of the parties will be responsible
for all costs (including, but not limited to, legal fees and expenses) incurred
by it in connection with the transactions; and

(c)    upon Closing, APT
Canada will be responsible for all costs incurred in connection with the
transactions contemplated hereby, including APTs and Krantzs reasonable legal,
audit and transaction costs (not to exceed CAD$20,000).

|8. | Enurement
|-- | ---------

8.1    This Agreement will enure to the benefit of
and be binding upon the parties hereto and their respective heirs, successors,
administrators and permitted assigns.

|9. | General Provisions
|-- | ------------------

9.1    Time is of the essence of this
Agreement.

9.2    The parties covenant and agree to execute
and deliver all such further documents and

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instruments and to do all acts and things as may be necessary or
desirable to carry out the full intent and meaning of is Agreement.

9.3    The proper law of this Agreement is the law
of the Province of British Columbia.

9.4    This Agreement may be executed in several
counterparts and by facsimile transmission, each of which will be deemed to be
an original and all of which will together constitute one and the same
instrument.

IN WITNESS WHEREOF the parties have executed this Agreement
as of the day and year first above written.



ADVANCED PROTEOME THERAPEUTICS, INC.

By:  __________________

Authorized Signatory



ADVANCED PROTEOME THERAPEUTICS CORP.

By:  __________________

Authorized Signatory

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