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Exhibit 31.1

                                 CERTIFICATIONS

I, Candace Kendle, certify that:

      1.    I have reviewed this annual report on Form 10-K of Kendle
            International Inc.;

      2.    Based on my knowledge, this annual report, does not contain any
            untrue statement of a material fact or omit to state a material fact
            necessary to make the statements made, in light of the circumstances
            under which such statements were made, not misleading with respect
            to the period covered by this annual report;

      3.    Based on my knowledge, the financial statements, and other financial
            information included in this annual report, fairly present in all
            material respects the financial condition, results of operations and
            cash flows of the registrant as of, and for, the periods presented
            in this annual report;

      4.    The registrant's other certifying officer and I are responsible for
            establishing and maintaining disclosure controls and procedures (as
            defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal
            control over financial reporting (as defined in Exchange Act Rules
            13a-15(f) and 15d-15(f)) for the registrant and have:

                  a.    designed such disclosure controls and procedures, or
                        caused such disclosure controls and procedures to be
                        designed under our supervision, to ensure that material
                        information relating to the registrant, including its
                        consolidated subsidiaries, is made known to us by others
                        within those entities, particularly during the period in
                        which this annual report is being prepared;

                  b.    designed such internal control over financial reporting,
                        or caused such internal control over financial reporting
                        to be designed under our supervision, to provide
                        reasonable assurance regarding the reliability of
                        financial reporting and the preparation of financial
                        statements for external purposes in accordance with
                        generally accepted accounting principles;

                  c.    evaluated the effectiveness of the registrant's
                        disclosure controls and procedures and presented in this
                        annual report our conclusions about the effectiveness of
                        the disclosure controls and procedures, as of the end of
                        the period covered by this report based on such
                        evaluation; and

                  d.    disclosed in this annual report any change in the
                        registrant's internal control over financial reporting
                        that occurred during the registrant's fourth fiscal
                        quarter that has materially affected, or is reasonably
                        likely to materially affect, the registrant's internal
                        control over financial reporting; and

      5.    The registrant's other certifying officer and I have disclosed,
            based on our most recent evaluation of internal control over
            financial reporting, to the registrant's auditors and the audit
            committee of the registrant's board of directors:

                  a.    all significant deficiencies and material weaknesses in
                        the design or operation of internal controls over
                        financial reporting which are reasonably likely to
                        adversely affect the registrant's ability to record,
                        process, summarize and report financial information; and

                  b.    any fraud, whether or not material, that involves
                        management or other employees who have a significant
                        role in the registrant's internal control over financial
                        reporting.

DATE SIGNED: March 16, 2006                             /s/ Candace Kendle
                                                        ------------------------
                                                        Candace Kendle
                                                        Chairman and CEO