exv4w25



 


Exhibit 4.25



Confidential treatment has been requested for certain portions of
this exhibit. The copy filed herewith omits the information subject
to the confidential treatment request. Omissions are designated as
“[*****]” or “*****”. A complete
version of this exhibit has been filed separately with the Commission
pursuant to an application for confidential treatment under
Rule 24b-2 promulgated under the Securities Exchange Act of
1934, as amended.




	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	

	 	 	
AMENDMENT OF SOLICITATION/MODIFICATION
OF CONTRACT
	 	1.
	 	CONTRACT ID CODE

        N/A
	 	 	 	 	 	PAGE

1
	 	OF
	 	PAGES

2
	

	2.	 	
AMENDMENT/MODIFICATION NO.
	 	3.
	 	EFFECTIVE DATE
	 	4.
	 	REQUISITION/PURCHASE REQ. NO.
	 	5.
	 	PROJECT NO. (If applicable)
	 	 	
00007
	 	 	 	See Block 16C	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	

	6.	 	
ISSUED BY
	 	CODE  
	 	7.
	 	ADMINISTERED BY (If other than Item 6)
	 	 	 	CODE   	 	 	 	 	 	 
	 	 	
Centers for Disease Control and
Prevention (CDC)

Acquisition & Assistance Branch B, (PGO)

2920 Brandwine Road, Rm. 3000

Atlanta, GA 30341-5539	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	

	8.	 	
NAME AND ADDRESS OF CONTRACTOR
(No., street, county, State and
ZIP Code)
	 	(   )
	 	9A.
	 	AMENDMENT OF SOLICITATION NO.
 


	 	 	
   Acambis, Inc.

   38 Sidney Street

   Cambridge, MA 02139

    

     
	 	 	 	 	 	 	 	 	 	9B.
	 	DATED (See Item 11)
 


	 	 	 	 	 	 	 	 	 	 	 	10A.
	 	MODIFICATION OF CONTRACT/ORDER NO.
	 	 	 	 	 	 	 	 	 	 	 	 	 	200-2002-00004
 


	 	 	 	 	 	 	 	 	 	X
	 	10B.
	 	DATED (See Item 13)
	 	 	 
	CODE      651	 	 	 	FACILITY CODE
	 	 	 	 	 	 	 	11/28/01	 	 	 	 	 	 	 	 	 	 
	





	 
	11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS
	

	o The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers o is extended, o is not extended.
	Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:
	(a) By completing Items 8 and 15, and returning      copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer
submitted; or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEGMENT
TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT
IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter,
provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.
	

	12. ACCOUNTING AND APPROPRIATION DATA (If required)
	Appropriation: 75X0140  Allowance: 2-B2316  OCC: 25.55  CAN: 2921-ATB1  Amt: ****** (Increase)
	

	13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,
	IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.
	





	 	 	 	 	 
	(ü)	 	
A.
	 	THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.
	

	 	 	
B.
	 	THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation date, etc.) SET
FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).
	

	 	 	
C.
	 	THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:
	 	 	 	 	 
	

	X	 	
D.
	 	OTHER (Specify type of modification and authority)
	 	 	 	 	FAR 52.232-22,  Limitation of Funds (APR 1984)
	





	 
	E. IMPORTANT: Contractor x is not, o is required to sign this document and return     copies to the issuing office.
	

	14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)
	 
	The purpose of this modification is to incrementally fund Section B, paragraph B.1, of the subject contract.  This action represents full funding for CLIN 0001.
	 
	Page 2 is attached hereto and made a part hereof. 
	 
	 
	Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.
	





	 	 	 	 	 	 	 	 	 	 	 	 	 	 	 
	15A.	 	
NAME AND TITLE OF SIGNER (Type or print)
	 	 	16A.
	 	NAME OF CONTRACTING OFFICER	 	 	 	 
	 	 	 	 	 	 	 	 	 	 	Lorenzo J. Falgiano	 	 	 	 
	

	15B.	 	
CONTRACTOR/OFFEROR
	 	 	 	 	 	16B.
	 	UNITED STATES OF AMERICA	 	 	 	 
	 	 	
 
	 	15C.
	 	DATE SIGNED
	 	 	 	 	 	16C.
	 	DATE SIGNED
	 	 	 	 	 	 	 
	 	BY	 	 	 	 	 	MAY 30 2003
	 	 	
	 	 	 	 	 	 	 	
	 	 	 	 
	 	 	
(Signature of person authorized to sign)
	 	 	 	 	 	 	 	(Signature of Contracting Officer)	 	 	 	 
	





	NSN 7540-01-152-8070	 	 	 	STANDARD FORM 30 (REV. 10-83)
	PREVIOUS EDITION UNUSABLE	 	
30-105
	 	Prescribed by GSA
	 	 	 	 	FAR (48 CFR) 53.243





 







 




Section B, paragraph B.1, Consideration is hereby deleted in its entirety and
the following substituted therefor:



B.1  352.232 CONSIDERATION, FIRM-FIXED PRICE, INCREMENTALLY FUNDED LINE ITEM




	 	 	 	 	 	 	 	 	 
	LINE ITEM	 	SUPPLIES/SERVICES	 	ESTIMATED	 	UNIT	 	EXTENDED
	 	 	 	 	QUANTITY/	 	PRICE	 	PRICE
	 	 	 	 	UNIT	 	MONTH	 	 
	
	 	
	 	
	 	
	 	

	 	 	 	 	 	 	 	 	 
	0001	 	
Development,
Production and
FDA Licensure of
Smallpox Vaccine
	 	22 months
	 	******
	 	******



Guaranteed Minimum:   $3,000,000.00





	 	(a)	 	It is determined that the total price to the Government for full
performance of this line item will be ******
	 
	 	(b)	 	Total funds currently available for payment and allotted to this
line item are ******. For further provisions on funding, see
Limitations of Funds Clause.
	 
	 	(c)	 	It is estimated that the amount currently allotted will cover
performance of Item 0001 through September 30, 2003.
	 
	 	(d)	 	The Contracting Officer may allot additional funds to the contract
without the concurrence of the Contractor.
	 
	 	(e)	 	Monthly payments will be made upon submission of a properly
executed invoice and submission of the Monthly Progress Report required
per Section C.8. of the Statement of Work.



The contract funded amount is hereby increased from ****** to ******, and
increase of ******, and the period of performance remains unchanged by reason
of this modification.





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