EXHIBIT
10.1  


 


AGREEMENT
BETWEEN ORCHESTRA MEDICAL VENTURES, LLC AND CORBUS


PHARMACEUTICALS
HOLDINGS, INC.


 


THIS
AGREEMENT is made as of this 20th day of September 2016, by and between Orchestra Medical Ventures, LLC, a Delaware limited
liability company (“Orchestra”) and Corbus Pharmaceuticals Holdings, Inc., a Delaware corporation (“Corbus”).


 


WHEREAS,
Orchestra is a healthcare investment management firm capable of providing consulting and advisory services to Corbus.


 


NOW
THEREFORE, in consideration of the mutual covenants of the parties set forth in this Agreement and other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows:


 


1.
Term & Obligations The term of this Agreement shall be for six (6) months from the date hereof. This Agreement
may be extended by mutual agreement of the parties. During the term of this Agreement, Orchestra shall provide a variety of consulting
and advisory services to Corbus relating principally to identifying and evaluating strategic relationships, licensing opportunities,
and business strategies.


 


2.
Consideration to Consultant During the term of this Agreement, Corbus shall provide cash compensation to Orchestra
in an aggregate amount of $100,000, payable in equal installments, monthly in advance, with the first payment to be made on October
1, 2016. In addition, as previously approved by Corbus’ Compensation Committee, effective as of September 16, 2016, Corbus
shall provide an equity incentive award to Orchestra consisting of options to purchase 50,000 shares (the “Option Shares”)
of the Company’s common stock, par value $0.0001 per share (the “Option Award”) pursuant to the Company’s
2014 Equity Compensation Plan (the “Plan”). The Option Award shall be made in accordance with the terms of
the Plan and fifty percent (50%) of the Option Shares will vest on the three (3) month anniversary of the date of grant of the
Option Award with the remainder of the Option Shares vesting on the six (6) month anniversary of the date of grant of the Option
Award.


 


3.
Independent Contractor Status The parties intend for the relationship between Corbus and Orchestra to be that of an
independent contractor. Orchestra shall be responsible for all income and other taxes imposed on Orchestra under applicable law
by reason of any of the payments made by Corbus and its affiliates pursuant to this Agreement.


 


4.
Confidential Information


 


	 	i)	Corbus
    Information. At all times during the term of this Agreement and thereafter, Orchestra and its officers, directors
    and affiliates shall hold in strictest confidence, and not use, except for the benefit of Corbus and its affiliates, or disclose
    to any person, firm or corporation without written authorization of the Board of Directors of Corbus, any Confidential Information
    of Corbus or its affiliates. “Confidential Information” means any proprietary information, technical data,
    trade secrets or know-how of Corbus and its affiliates, including, but not limited to, research, product plans, products,
    services, customer lists and customers, markets, software, developments, inventions, processes, formulas, technology, designs,
    drawings, engineering, hardware configuration information, marketing, finances or other business information disclosed to
    Orchestra by Corbus or its affiliates either directly or indirectly, in writing, orally, by drawings, or by observation of
    parts or equipment. Confidential Information does not include any of the foregoing items that have become publicly known and
    made generally available through no wrongful act of Orchestra or of others who were under confidentiality obligations as to
    the item or items involved.


 




    	 	 	 



    	 	 	 



    

 


	 	ii)	Consultant’s
    Information. At all times during the term of this Agreement and thereafter, Corbus and its other consultants, directors,
    investors and affiliates, shall hold in strictest confidence, and not use, or disclose to any person, firm or corporation
    without written authorization of Orchestra any Confidential Information of Orchestra. Thus, “Confidential Information”
    also means any proprietary information, technical data, trade secrets or know-how of Orchestra, including, but not limited
    to, research, product plans, products, services, software, developments, inventions, processes, formulas, technology, designs,
    drawings, engineering, hardware configuration information, marketing, or other business information disclosed to Corbus and
    its other consultants, directors, investors and affiliates, by Orchestra either directly or indirectly, in writing, orally,
    by drawings, or by observation of parts or equipment. Confidential Information does not include any of the foregoing items
    that have become publicly known and made generally available through no wrongful act of Corbus or of others who were under
    confidentiality obligations as to the item or items involved.


 


5.
Separability of Terms Each obligation and consideration in this Agreement is separately enforceable and the parties’
requirements to perform these obligations are separate and independent. In the event any provision, paragraph or clause either
lapses in its terms or becomes unenforceable for any reason all remaining provisions, paragraphs or clauses shall remain in full
force and effect.


 


6.
Notices All notices or other communications hereunder shall be in writing and shall be deemed to have been duly given
if delivered personally, by recognized overnight courier marked for overnight delivery, or by registered or certified mail, postage
prepaid, address as follows:


 


If
to Orchestra, to:


 


David
Hochman


Managing
Partner


Orchestra
Medical Ventures, LLC


150
Union Square Drive


New Hope, PA 18938


E-mail:
dhochman@orchestramv.com


 




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or
at such other address at which Orchestra may from time to time maintain its principal executive offices.


 


If
to Corbus, at:


 


Yuval
Cohen, PhD


Corbus
Pharmaceuticals Holdings, Inc.


100
River Ridge Drive, Suite 103


Norwood,
MA 02062


E-mail: ycohen@corbuspharma.com


Telephone: (617) 963-0102


 


or
at such other address at which Corbus may from time to time maintain its principal executive offices.


 


All
such notices and communications shall be effective, or if sent by nationally recognized overnight courier service, one business
day after delivery to such courier service marked for overnight delivery, or, if mailed, when received, or if e-mailed upon confirmation
of receipt.


 


7.
Applicable Law This Agreement shall be governed by, and construed in accordance with, the internal laws of the State
of New York, without reference to or application of any conflicts of laws principles.


 


8.
Counterparts This Agreement may be executed in one or more counterparts, each of which shall be deemed an original,
but all of which together shall constitute one and the same instrument.


 


So
Accepted and Agreed:


 


	ORCHESTRA
    MEDICAL VENTURES, LLC	 
	 	 	 
	By:	/s/
    David Hochman 	 
	 	David
    Hochman, Managing Partner	 


 


	CORBUS
    PHARMACEUTICALS HOLDINGS, INC	 
	 	 	 
	By:	/s/
    Sean Moran	 
	 	Sean
    Moran, Chief Financial Officer 	 


 




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