**Exhibit 24**

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints**Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and allcapacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, and any and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connectiontherewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to allintents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtuehereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ ***Michael Celano*SignatureMichael CelanoPrint Name

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ *****Jack Goldstein, Ph.D.*SignatureJack Goldstein, Ph.D.Print Name

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ *******Ronny B. Lancaster*SignatureRonny B. LancasterPrint Name

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ *********Charles W. Patrick*SignatureCharles W. PatrickPrint Name

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ ***********Roger L. Pringle*SignatureRoger L. PringlePrint Name

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ *************Ronald H. Spair*SignatureRonald H. SpairPrint Name

**POWER OF ATTORNEY**

KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints **Mark L. Kuna, and Jack E. Jerrett,**and each of them, his true and lawful attorneys-in-fact and agents, with full power ofsubstitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc., for the year ended December 31, 2008, andany and all amendments to such report and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, fullpower and authority to do and perform each and every act and thing requisite and necessary to be done, as fully to all intents and purposes as the undersigned might or could do in person, hereby ratifying and confirming all that saidattorneys-in-fact and agents, or each of them or their or his substitute or substitutes, may lawfully do or cause to be done by virtue hereof. 

IN WITNESS WHEREOF, this Power of Attorney has been signed by the undersigned effective as of February 16, 2009. 

 
/s/ *************Douglas G. Watson*SignatureDouglas G. WatsonPrint Name