**CERTIFICATIONS**

**EXHIBIT        31.1**

| 1.   | I                  have reviewed this Quarterly                  Report on Form 10-Q of OccuLogix,                  Inc.; |
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| 2.    | Based                  on my knowledge, this                  quarterly report does not contain any untrue statement of a material                  fact                  or omit to state a material fact necessary to make the statements                  made, in                  light of the circumstances under which such statements were made,                  not                  misleading with respect to the period covered by this quarterly                  report; |
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| 3.   | Based                  on my knowledge, the                  financial statements, and other financial information included                  in this                  quarterly report, fairly present in all material respects the financial                  condition, results of operations and cash flows of the registrant                  as of,                  and for, the periods presented in this quarterly                  report; |
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| 4.   | The                  registrant’s other certifying officer and I are responsible for                  establishing and maintaining disclosure controls and procedures                  (as                  defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal                  control over financial reporting (as defined in Exchange Act Rules                  13a-15(f) and 15d-15(f)) for the registrant and                  have: |
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| (a)   | Designed                  such disclosure controls and procedures, or caused such disclosure                  controls and procedures to be designed under our supervision, to                  ensure                  that material information relating to the registrant, including                  its                  consolidated subsidiaries, is made known to us by others within                  those                  entities, particularly during the period in which this quarterly                  report is                  being prepared; |
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| (b)   | Designed                  such internal control over financial reporting, or caused such                  internal                  control over financial reporting to be designed under our supervision,                  to                  provide reasonable assurance regarding the reliability of financial                  reporting and the preparation of financial statements for external                  purposes in accordance with generally accepted accounting                  principles; |
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| (c)   | Evaluated                  the effectiveness of the registrant’s disclosure controls and procedures                  and presented in this quarterly report our conclusions about the                  effectiveness of the disclosure controls and procedures, as of                  the end of                  the period covered by this quarterly report based on such evaluation;                  and |
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| (d)   | Disclosed                  in this report any change in the registrant’s internal control over                  financial reporting that occurred during the period covered by                  this                  quarterly report that has materially affected, or is reasonably                  likely to                  materially affect, the registrant’s internal control over financial                  reporting. |
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| 5.    | The                  registrant’s other certifying officer and I have disclosed, based on our                  most recent evaluation of internal control over financial reporting,                  to                  the registrant’s auditors and the audit committee of registrant’s board of                  directors (or persons performing the equivalent                  functions): |
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| (a)   | All                  significant deficiencies and material weaknesses in the design                  or                  operation of internal control over financial reporting which are                  reasonably likely to adversely affect the registrant’s ability to record,                  process, summarize and report financial information;                  and |
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| (b)   | Any                  fraud, whether or not material, that involves management or other                  employees who have a significant role in the registrant’s internal control                  over financial reporting. |
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|                                                                      | **OCCULOGIX,                  INC.**           |
|                                                                 |                                      |                                |
| Date:   November                  9,                  2007 | By:                                  | /s/ Elias                  Vamvakas |
|                                                                      |  Chief                  Executive Officer |
|                                                                      |                                           |

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