**Exhibit 10.35**

**RELEASE AGREEMENT**

               This Agreement (this "**Release Agreement**") dated as of February 28, 2002 is entered into by and among **Procept,Inc.** (formerly Pacific Pharmaceuticals, Inc.) ("**Procept**"), **AOI Pharmaceuticals, Inc.** (a subsidiary ofAccess Oncology, Inc.) ("**AOIP**") and the United States Public Health Services ("**PHS**")(**Procept**, **AOIP** and **PHS**, collectively, the "**Parties**").

**                WHEREAS,** The Penn State Research Foundation ("**Foundation**"), the University of Chicago ("**UC**") and**PHS** are owners of certain patent rights associated with 06-Benzylguanine and/or its derivatives;

**                WHEREAS,****Foundation** executed the following interinstitutional agreements with **PHS**:  L-094-91/0, executed May 20, 1997(attached as Exhibit A); and with **UC** (Arch Foundation) executed (May 16, 1997) (attached as Exhibit B) whereby **UC** andthe **Foundation** received full power and authority to enter into a license agreement with **Procept** on or about February6, 1998 (such license agreement, the "**License Agreement**" attached as Exhibit C), pursuant to which**Procept** received an exclusive worldwide license to certain **Patent Rights** (as defined therein);

**                WHEREAS,****UC** under an agreement with its affiliated corporation, ARCH Development Corporation has the right to license theLicensed Patents and other intellectual property owned by ARCH;

**                WHEREAS,****Procept** has sub-licensed certain of its interests, rights and obligations under the License **Agreement** to**AOIP** pursuant to a sublicense agreement entered into by and between **Procept** and **AOIP** on or about October 13,2000 (such sublicense agreement, the "**Sublicense****Agreement**" attached as Appendix D);

**                WHEREAS,****UC**, **Foundation** and the **PHS** have agreed to enter into the following interinstitutional agreements("**Interinstitutional Agreements**"):  L-086-02/0, executed January 30, 2002; and L-067-02/0, executed January29, 2002, copies of which are attached hereto as Exhibits E and F and pursuant to which **PHS** has exclusive licensing rightsassociated with the **Patent Rights**;

**                WHEREAS,****Procept** and **PHS** have executed a revised license agreement dated February 28, 2002, L-068-02/0 ("**RevisedLicense Agreement**"), to which this **Release Agreement** is attached regarding the **Patent Rights** licensed to**PHS** which **Revised License Agreement** shall supercede and terminate the terms and conditions of the License**Agreement**;

**                WHEREAS,** all of the **Parties** acknowledge that they will each derive substantial benefit from the **Revised License Agreement**,the **Sublicense Agreement** and **AOIP**’s development efforts thereunder;

**                NOW, THEREFORE,** in consideration of the foregoing premises and the mutual covenants herein contained, and for other good and valuableconsideration, the receipt and sufficiency of which is hereby acknowledged, the **Parties** agree as follows:

- **PHS**hereby irrevocably and absolutely releases and forever discharges bath **Procept** and **AOIP**, as well as their affiliates,and their respective successors, predecessors, assigns, beneficiaries, executors, trustees, administrators, subrogees, agents,representatives, employees, officers, directors, shareholders, partners, parent corporations, subsidiaries and affiliates(collectively, "**Released Parties**"), of and from any and all claims, demands, obligations, debts, actions, andcauses of action of every nature, character, and description, known or unknown, pursuant to, arising out of, or related to theLicense **Agreement**, which **PHS** now owns or holds, or has at any time heretofore owned or held, or may at any time ownor hold against the **Released Parties**, arising prior to and including the date of this Agreement.

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-  In the eventthe **Revised License Agreement** is terminated owing to a breach by **Procept** (as determined by a court of competentjurisdiction or specific reference in a settlement of litigation) and **AOIP** is in good standing under the **SublicenseAgreement**, **PHS** will grant a license directly to **AOIP** on substantially similar terms and conditions as thosecontained in the **Revised License Agreement** (such newly granted license, the "**New AOIP License**").  Itis understood and agreed that unless and until such **New AOIP License** is executed, **AOIP** shall maintain its exclusiveSublicense to the **Patent Rights** (as defined in the **Sublicense Agreement**) in accordance with the **SublicenseAgreement**.  It is further understood and agreed that the **Sublicense Agreement** shall terminate upon execution of the**New AOIP License**.  It is further understood and agreed to by **PHS** and **AOIP** that the royalty considerationto be paid to **PHS** under the terms and conditions of the **New AOIP License** shall be the same as those terms containedin Appendix C of the **Revised License Agreement**. 
-  Theconstruction, validity, performance, and effect of this **Agreement** shall be governed by Federal law as applied by the Federalcourts in the District of Columbia. 
-   This**Agreement** may be signed in one or more counterparts, each of which is to be considered an original, and taken together asone and the same document. 

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                **IN WITNESS WHEREOF**, the **Parties** acknowledge by the signatures below of their authorizedrepresentatives that they have read this Agreement and understand and agree to be bound by its terms and conditions.

 

| PROCEPT,    INC.    369 Lexington Avenue     10th Floor    New York, New York 10017 
By:                                                                        

Name:                                                                    

Title:                                                                     

 AOI PHARMACEUTICALS, INC.    An Access Oncology Company    750 Lexington AvenueNew York, New York 10022
By:                                                                        

Name:                                                                    

Title:                                                                     

   UNITED STATES PUBLIC HEALTH SERVICE
 

By:                                                                        

Name:                                                                   

Title:                                                                     

  
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