Exhibit 10.1

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LOAN AND SECURITY AGREEMENT



by and between



SILICON VALLEY BANK

3003 Tasman Drive

Santa Clara, CA 95054

Attn: Loan Services

(408) 496-2429



and



XENOGEN CORPORATION

860 Atlantic Avenue

Alameda, California 94501



TOTAL CREDIT AMOUNT: $3,000,000



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TABLE OF CONTENTS



|   |  |                                |  |                                                     |  |     
|-- |  | ------------------------------ |  | --------------------------------------------------- |  | ----
|   |  |                                |  |                                                     |  | Page
|1. |  | ACCOUNTING AND OTHER TERMS.    |  | 1                                                  
|   |  |                               
|2. |  | LOAN AND TERMS OF PAYMENT      |  | 1                                                  
|   |  |                                | 
|   |  | 2.1                            |  | Credit Extensions.                                  |  | 1   
|   |  | 2.2                            |  | Overadvances.                                       |  | 1   
|   |  | 2.3                            |  | Interest Rate, Payments.                            |  | 2   
|   |  | 2.4                            |  | Fees.                                               |  | 2   
|   |  |                               
|3. |  | CONDITIONS OF LOANS            |  | 2                                                  
|   |  |                                | 
|   |  | 3.2                            |  | Conditions Precedent to all Credit Extensions.      |  | 3   
|   |  |                               
|4. |  | CREATION OF SECURITY INTEREST  |  | 3                                                  
|   |  |                                | 
|   |  | 4.1                            |  | Grant of Security Interest.                         |  | 3   
|   |  |                               
|5. |  | REPRESENTATIONS AND WARRANTIES |  | 4                                                  
|   |  |                                | 
|   |  | 5.1                            |  | Due Organization and Authorization.                 |  | 4   
|   |  | 5.2                            |  | Collateral.                                         |  | 4   
|   |  | 5.3                            |  | Litigation.                                         |  | 4   
|   |  | 5.4                            |  | No Material Adverse Change in Financial Statements. |  | 4   
|   |  | 5.5                            |  | Solvency.                                           |  | 5   
|   |  | 5.6                            |  | Regulatory Compliance.                              |  | 5   
|   |  | 5.7                            |  | Subsidiaries.                                       |  | 5   
|   |  | 5.8                            |  | Full Disclosure.                                    |  | 5   
|   |  |                               
|6. |  | AFFIRMATIVE COVENANTS          |  | 5                                                  
|   |  |                                | 
|   |  | 6.1                            |  | Government Compliance.                              |  | 6   
|   |  | 6.2                            |  | Financial Statements, Reports, Certificates.        |  | 6   
|   |  | 6.3                            |  | Inventory; Returns.                                 |  | 6   
|   |  | 6.4                            |  | Taxes.                                              |  | 7   
|   |  | 6.5                            |  | Insurance.                                          |  | 7   
|   |  | 6.6                            |  | Accounts.                                           |  | 7   
|   |  | 6.7                            |  | Financial Covenants.                                |  | 7   
|   |  | 6.8                            |  | Intentionally Omitted.                              |  | 7   
|   |  | 6.9                            |  | Control Agreements.                                 |  | 7   
|   |  | 6.10                           |  | Further Assurances.                                 |  | 8   



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|    |  |                                             |  |                                                                   |  |   
|--- |  | ------------------------------------------- |  | ----------------------------------------------------------------- |  | --
|7.  |  | NEGATIVE COVENANTS                          |  | 8                                                                
|    |  |                                             | 
|    |  | 7.1                                         |  | Dispositions.                                                     |  | 8 
|    |  | 7.2                                         |  | Changes in Business, Ownership, Management or Business Locations. |  | 8 
|    |  | 7.3                                         |  | Mergers or Acquisitions.                                          |  | 8 
|    |  | 7.4                                         |  | Indebtedness.                                                     |  | 9 
|    |  | 7.5                                         |  | Encumbrance.                                                      |  | 9 
|    |  | 7.6                                         |  | Distributions; Investments.                                       |  | 9 
|    |  | 7.7                                         |  | Transactions with Affiliates.                                     |  | 9 
|    |  | 7.8                                         |  | Subordinated Debt.                                                |  | 9 
|    |  | 7.9                                         |  | Compliance.                                                       |  | 10
|    |  |                                            
|8.  |  | EVENTS OF DEFAULT                           |  | 10                                                               
|    |  |                                             | 
|    |  | 8.1                                         |  | Payment Default.                                                  |  | 10
|    |  | 8.2                                         |  | Covenant Default.                                                 |  | 10
|    |  | 8.3                                         |  | Material Adverse Change.                                          |  | 10
|    |  | 8.4                                         |  | Attachment.                                                       |  | 10
|    |  | 8.5                                         |  | Insolvency.                                                       |  | 11
|    |  | 8.6                                         |  | Other Agreements.                                                 |  | 11
|    |  | 8.7                                         |  | Judgments.                                                        |  | 11
|    |  | 8.8                                         |  | Misrepresentations.                                               |  | 11
|    |  | 8.9                                         |  | Guaranty.                                                         |  | 11
|    |  |                                            
|9.  |  | BANKS RIGHTS AND REMEDIES                  |  | 12                                                               
|    |  |                                             | 
|    |  | 9.1                                         |  | Rights and Remedies.                                              |  | 12
|    |  | 9.2                                         |  | Power of Attorney.                                                |  | 12
|    |  | 9.3                                         |  | Accounts Collection.                                              |  | 13
|    |  | 9.4                                         |  | Bank Expenses.                                                    |  | 13
|    |  | 9.5                                         |  | Banks Liability for Collateral.                                  |  | 13
|    |  | 9.6                                         |  | Remedies Cumulative.                                              |  | 13
|    |  | 9.7                                         |  | Demand Waiver.                                                    |  | 14
|    |  |                                            
|10. |  | NOTICES                                     |  | 14                                                               
|    |  |                                            
|11. |  | CHOICE OF LAW , VENUE AND JURY TRIAL WAIVER |  | 14                                                               
|    |  |                                            
|12. |  | GENERAL PROVISIONS                          |  | 14                                                               
|    |  |                                             | 
|    |  | 12.1                                        |  | Successors and Assigns.                                           |  | 14
|    |  | 12.2                                        |  | Indemnification.                                                  |  | 14
|    |  | 12.3                                        |  | Time of Essence.                                                  |  | 15
|    |  | 12.4                                        |  | Severability of Provision.                                        |  | 15
|    |  | 12.5                                        |  | Amendments in Writing, Integration.                               |  | 15



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|    |  |             |  |                                      |  |   
|--- |  | ----------- |  | ------------------------------------ |  | --
|    |  | 12.6        |  | Counterparts.                        |  | 15
|    |  | 12.7        |  | Survival.                            |  | 15
|    |  | 12.8        |  | Confidentiality.                     |  | 15
|    |  | 12.9        |  | Attorneys Fees, Costs and Expenses. |  | 16
|    |  |            
|13. |  | DEFINITIONS |  | 16                                  
|    |  |             | 
|    |  | 13.1        |  | Definitions.                         |  | 16



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This LOAN AND SECURITY AGREEMENT dated September 10, 2003, between SILICON VALLEY BANK (Bank), whose
address is 3003 Tasman Drive, Santa Clara, California 95054 and XENOGEN CORPORATION, a Delaware corporation (Borrower), whose address is 860 Atlantic Avenue, Alameda, California 94501 provides the terms on which Bank will lend to
Borrower and Borrower will repay Bank. The parties agree as follows:



1. ACCOUNTING AND OTHER TERMS.



Accounting terms not defined in this Agreement will be construed following GAAP. Calculations and determinations must be made following GAAP. The term financial statements includes the notes and schedules. The terms
including and includes always mean including (or includes) without limitation, in this or any Loan Document.



2. LOAN AND TERMS OF PAYMENT



2.1 Credit Extensions.



Borrower will pay Bank the unpaid principal amount of all Credit Extensions and interest on the unpaid principal amount of the Credit Extensions.



2.1.1Revolving Advances.



(a) Bank will make Advances not exceeding the Committed
Revolving Line. Amounts borrowed under this Section may be repaid and reborrowed during the term of this Agreement.



(b) To obtain an Advance, Borrower must notify Bank by facsimile or telephone by 12:00 noon Pacific time on the Business Day the Advance is to be made.
Borrower must promptly confirm the notification by delivering to Bank the Payment/Advance Form attached as Exhibit B. Bank will credit Advances to Borrowers deposit account. Each Advance must be in a minimum amount of $100,000. Bank may make
Advances under this Agreement based on instructions from a Responsible Officer or his or her designee or without instructions if the Advances are necessary to meet Obligations which have become due. Bank may rely on any telephone notice given by a
person whom Bank believes is a Responsible Officer or designee. Borrower will indemnify Bank for any loss Bank suffers due to such reliance.



(c) The Committed Revolving Line terminates on the Revolving Maturity Date, when all Advances are immediately payable.



2.2 Overadvances.



If Borrowers Obligations under Section 2.1.1 exceed the Committed
Revolving Line, Borrower must immediately pay Bank the excess.



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2.3 Interest Rate, Payments.



(a) Interest Rate. Advances accrue interest on the outstanding principal
balance at a per annum rate equal to the greater of: (i)150 basis points (1.50%) above the Prime Rate or (ii) five and one half percent (5.5%). Upon the occurrence and during the continuance of an Event of Default, Obligations accrue interest at 5
percent above the rate effective immediately before the Event of Default. The interest rate increases or decreases when the Prime Rate changes. Interest is computed on a 360 day year for the actual number of days elapsed.



(b) Payments. Interest due on the Committed Revolving Line is payable on the
first day of each month. Bank may debit any of Borrowers deposit accounts including Account Number
 for principal and interest payments owing or any amounts Borrower owes
Bank. Bank will promptly notify Borrower when it debits Borrowers accounts. These debits are not a set-off. Payments received after 12:00 noon Pacific time are considered received at the opening of business on the next Business Day. When a
payment is due on a day that is not a Business Day, the payment is due the next Business Day and additional fees or interest accrue.



2.4 Fees.



Borrower will pay:



(a) Loan Fee. Borrower shall pay Bank a loan fee in the amount of $60,000, fully earned on the Closing Date and payable as follows: (y) $30,000 payable on
the Closing Date and (z) $30,000 payable on the earlier of: (1) the first anniversary of the Closing Date or (2) the termination of this Agreement.



(b) Bank Expenses. All Bank Expenses (including reasonable attorneys fees and reasonable expenses) incurred through and after the date of this
Agreement, are payable when due.



3.
CONDITIONS OF LOANS



Banks obligation to make the
initial Credit Extension is subject to the following conditions precedent:



(a) receipt by Bank of the Borrowers resolution authorizing the transaction in form and substance satisfactory to Bank;



(b) receipt by Bank of the Loan Fee due on the Closing Date;



(c) receipt by Bank of Borrowers insurance certificate with Lenders loss payable endorsement reflecting Bank as loss payee;



(d) Intercreditor Agreement in form and substance satisfactory to Bank by and
between Bank and the lenders providing equipment financing;



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(e) receipt by Bank of Borrowers financial projections approved by Borrowers Board of
Directors; and



(f) receipt by Bank of all other agreement,
documents and fees that Bank may require.



3.2
Conditions Precedent to all Credit Extensions.



Banks obligations to make each Credit Extension, including the initial Credit Extension, is subject to the following:



(a) timely receipt of any Payment/Advance Form; and



(b) the representations and warranties in Section 5 must be materially true on the date of the Payment/Advance Form and on the effective date of each
Credit Extension and no Event of Default may have occurred and be continuing, or result from the Credit Extension (provided, however, that those representations and warranties expressly referring to another date shall be materially true as of such
date). Each Credit Extension is Borrowers representation and warranty on that date that the representations and warranties of Section 5 remain true.



4. CREATION OF SECURITY INTEREST



4.1 Grant of Security Interest.



Borrower grants Bank a continuing security interest in all presently existing and later acquired Collateral to secure all Obligations and performance of
each of Borrowers duties under the Loan Documents. Except for Permitted Liens, any security interest will be a first priority security interest in the Collateral. Notwithstanding the foregoing, the security interest granted herein does not
extend to and the term Collateral does not include any license or contract rights to the extent (i) the granting of a security interest in it would be contrary to applicable law, or (ii) that such rights are nonassignable by their terms
(but only to the extent such prohibition is enforceable under applicable law, including, without limitation, Section 9406 of the Code) without the consent of the licensor or other party (but only to the extent such consent has not been obtained).
Except as disclosed on the Schedule, Borrower is not a party to, nor is bound by, any material license or other similar agreement that prohibits or otherwise restricts Borrower from granting a security interest in Borrowers interest in such
license or agreement or any other property. Without prior notice to Bank, Borrower shall not enter into, or become bound by, any such license or agreement which is reasonably likely to have a material impact on Borrowers business or financial
condition. Borrower shall take such steps as Bank requests to obtain the consent of, or waiver by, any person whose consent or waiver is necessary for such licenses or contract rights to be deemed Collateral and for Bank to have a
security interest in it that might otherwise be restricted or prohibited by law or by the terms of any such license or agreement, whether now existing or entered into in the future. If this Agreement is terminated, Banks lien and security
interest in the Collateral will continue until Borrower fully satisfies its Obligations. Notwithstanding anything contained in this Agreement to the contrary, the term Collateral shall not include any property that is subject to a Lien that is
otherwise permitted pursuant to paragraph (c) of the definition of Permitted Liens and Bank agrees to execute any instruments



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or documents necessary to release its interest in such property and to effect the foregoing. Bank agrees to terminate its
security interest and any relating UCC-1 financing statements upon payment in full, in immediately available funds, of the Obligations.



5. REPRESENTATIONS AND WARRANTIES



Borrower represents and warrants as follows:



5.1 Due Organization and Authorization.



Borrower and each Subsidiary is duly existing and in good standing in its jurisdiction of formation and qualified and licensed to do business in, and
in good standing in, any state in which the conduct of its business or its ownership of property requires that it be qualified, except where the failure to do so could not reasonably be expected to cause a Material Adverse Change.



The execution, delivery and performance of the Loan Documents have been duly
authorized, and do not conflict with Borrowers formation documents, nor constitute an event of default under any material agreement by which Borrower is bound. Borrower is not in default under any agreement to which or by which it is bound in
which the default could reasonably be expected to cause a Material Adverse Change.



5.2 Collateral.



Borrower has good title to the Collateral, free of Liens except Permitted Liens. The Accounts are bona fide, existing obligations, and the service or
property has been performed or delivered to the account debtor or its agent for immediate shipment to and unconditional acceptance by the account debtor. All Inventory is in all material respects of good and marketable quality, free from material
defects.



5.3 Litigation.



Except as shown in the Schedule, there are no actions or proceedings
pending or, to the knowledge of Borrowers Responsible Officers and legal counsel, threatened by or against Borrower or any Subsidiary in which a likely adverse decision could reasonably be expected to cause a Material Adverse Change.



5.4 No Material Adverse Change in
Financial Statements.



All consolidated financial
statements for Borrower, and any Subsidiary, delivered to Bank fairly present in all material respects Borrowers consolidated financial condition and Borrowers consolidated results of operations. There has not been any material
deterioration in Borrowers consolidated financial condition since the date of the most recent financial statements submitted to Bank.



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5.5 Solvency.



The fair salable value of Borrowers assets (including goodwill minus disposition costs) exceeds the fair value of its
liabilities; the Borrower is not left with unreasonably small capital after the transactions in this Agreement; and Borrower is able to pay its debts (including trade debts) as they mature.



5.6 Regulatory Compliance.



Borrower is not an investment company or a company
controlled by an investment company under the Investment Company Act. Borrower is not engaged as one of its important activities in extending credit for margin stock (under Regulations T and U of the Federal Reserve Board of
Governors). Borrower has complied in all material respects with the Federal Fair Labor Standards Act. Borrower has not violated any laws, ordinances or rules, the violation of which could reasonably be expected to cause a Material Adverse Change.
None of Borrowers or any Subsidiarys properties or assets has been used by Borrower or any Subsidiary or, to the best of Borrowers knowledge, by previous Persons, in disposing, producing, storing, treating, or transporting any
hazardous substance other than legally. Borrower and each Subsidiary has timely filed all required tax returns and paid, or made adequate provision to pay, all material taxes, except those being contested in good faith with adequate reserves under
GAAP. Borrower and each Subsidiary has obtained all consents, approvals and authorizations of, made all declarations or filings with, and given all notices to, all government authorities that are necessary to continue its business as currently
conducted, except where the failure to do so could not reasonably be expected to cause a Material Adverse Change.



5.7 Subsidiaries.



Borrower does not own any stock, partnership interest or other equity securities except for Permitted Investments.



5.8 Full Disclosure.



No written representation, warranty or other statement of Borrower in any
certificate or written statement given to Bank (taken together with all such written certificates and written statements to Bank) contains any untrue statement of a material fact or omits to state a material fact necessary to make the statements
contained in the certificates or statements not misleading. It being recognized by Bank that the projections and forecasts provided by Borrower in good faith and based upon reasonable assumptions are not viewed as facts and that actual results
during the period or periods covered by such projections and forecasts may differ from the projected and forecasted results.



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6. AFFIRMATIVE COVENANTS



Borrower will do all of the following:



6.1 Government Compliance.



Borrower will maintain its and all Subsidiaries legal existence and
good standing in its jurisdiction of formation and maintain qualification in each jurisdiction in which the failure to so qualify would reasonably be expected to cause a material adverse effect on Borrowers business or operations. Borrower
will comply, and have each Subsidiary comply, with all laws, ordinances and regulations to which it is subject, noncompliance with which could have a material adverse effect on Borrowers business or operations or would reasonably be expected
to cause a Material Adverse Change.



6.2
Financial Statements, Reports, Certificates.



(a)
Borrower will deliver to Bank: (i) as soon as available, but no later than 30 days after the last day of each month, a company prepared consolidated balance sheet and income statement covering Borrowers consolidated operations during the
period, in a form and certified by a Responsible Officer acceptable to Bank; (ii) as soon as available, but no later than 120 days after the last day of Borrowers fiscal year, audited consolidated financial statements prepared under GAAP,
consistently applied, together with an opinion that is unqualified (other than on going concern qualification) or otherwise consented to by Bank on the financial statements from an independent certified public accounting firm reasonably acceptable
to Bank; (iii) within 5 days of filing, copies of all statements, reports and notices generally made available to Borrowers security holders or to any holders of Subordinated Debt; (iv) a prompt report of any legal actions pending or
threatened against Borrower or any Subsidiary that could result in damages or costs to Borrower or any Subsidiary of $250,000 or more; (v) as soon as available, but no later than 45 days after the last day of each fiscal year of Borrower,
Borrowers financial projections for the year approved by Borrowers Board of Directors; and (vi) budgets, sales projections, operating plans or other financial information Bank reasonably requests.



(b) Within 30 days after the last day of each month, Borrower will deliver to
Bank aged listings of accounts receivable and accounts payable, a detailed Deferred Revenue Schedule, and an Eligible Accounts Certificate on the form of Exhibit C.



(c) Within 30 days after the last day of each month, Borrower will deliver to Bank with the monthly financial statements a
Compliance Certificate signed by a Responsible Officer in the form of Exhibit D.



(d) Bank has the right to audit Borrowers Collateral at Borrowers expense, but the audits will be conducted no more often than once every year unless an Event of Default has occurred and is continuing.



6.3 Inventory; Returns.



Borrower will keep all Inventory in good and marketable condition, free from
material defects. Returns and allowances between Borrower and its account debtors will follow Borrowers customary practices as they exist at execution of this Agreement. Borrower must promptly notify Bank of all returns, recoveries, disputes
and claims, that involve more than $300,000 in the aggregate in any one fiscal year.



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6.4 Taxes.



Borrower will make, and cause each Subsidiary to make, timely payment of all material federal, state, and local taxes or
assessments, and will deliver to Bank, on demand, appropriate certificates attesting to the payment; provided that Borrower or a Subsidiary need not make any payment if the amount or validity of such payment is contested in good faith by appropriate
proceedings and is reserved against to the extent required by GAAP.



6.5 Insurance.



Borrower will keep its business and the Collateral insured for risks and in amounts, as Bank may reasonably request. Insurance policies will be in a form, with companies, and in amounts that are satisfactory to Bank in Banks
reasonable discretion. All property policies will have a lenders loss payable endorsement showing Bank as an additional loss payee and all liability policies will show the Bank as an additional insured and provide that the insurer must give
Bank at least 20 days notice before canceling its policy. At Banks request, Borrower will deliver certified copies of policies and evidence of all premium payments. If no Event of Default has occurred and is continuing, proceeds payable under
any casualty policy will, at Borrowers option, be payable to Borrower to replace the property subject to the claim, provided that any such replacement property shall be deemed Collateral in which Bank has been granted a first priority security
interest. If an Event of Default has occurred and is continuing, then, at Banks option, proceeds payable under any policy will be payable to Bank on account of the Obligations.



6.6 Accounts.



Borrower will maintain its primary operating accounts with Bank.
Additionally, Borrower agrees to transfer and maintain with Bank or Banks Affiliates all of its depository (other than operating accounts) and investment accounts so long as Banks and Banks Affiliates depository and investment
accounts products are competitive with those offered by Borrowers current depository institution and/or investment services provider.



6.7 Financial Covenants.



Borrower will maintain at all times:



(i) Quick Ratio. A ratio of unrestricted cash (and equivalents) maintained at Bank or one of its Affiliates plus Eligible Accounts divided by the
then total outstandings under all Credit Extensions of not less than 1.75 to 1.00.



6.8 Intentionally Omitted.



6.9 Control Agreements.



With respect to deposit accounts or investment accounts maintained at financial institutions other than Bank, within 15 days of the opening of any such
deposit account or investment account (or of the Closing Date for any deposit accounts and investment accounts



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existing as of the Closing Date), Borrower will execute and deliver to Bank, control agreements in form satisfactory to
Bank in order for Bank to perfect its security interest in Borrowers deposit accounts or investment accounts.



6.10 Further Assurances.



Borrower will execute any further instruments and take further action as Bank reasonably requests to perfect or continue Banks security interest in
the Collateral or to effect the purposes of this Agreement.



7. NEGATIVE COVENANTS



Borrower will not do any of the following without Banks prior written consent, which will not be unreasonably withheld:



7.1 Dispositions.



Convey, sell, lease, transfer or otherwise dispose of (collectively Transfer), or permit any of its Subsidiaries to Transfer, all or any part
of its business or property, other than Transfers (i) of Inventory in the ordinary course of business (including Transfers of the IVIS systems); (ii) of non-exclusive licenses and similar arrangements for the use of the property of Borrower or its
Subsidiaries in the ordinary course of business; (iii) of exclusive licenses of Intellectual Property entered into the ordinary course of business and approved in good faith by Borrowers Board of Directors, so long as: (x) such licenses are
limited to specific products or processes or a specific geographic area outside of the United States or Canada; (y) the duration of any such license does not exceed 5 years; and (z) such exclusive license arrangement is not tantamount to a sale of
the subject Intellectual Property; (iv) of worn-out or obsolete Equipment, (v) Transfers permitted by this Section 7, or (vi) other Transfers which in the aggregate do not exceed $250,000 in any fiscal year.



7.2 Changes in Business, Ownership, Management or
Business Locations.



Engage in or permit any of its
Subsidiaries to engage in any business other than the businesses currently engaged in by Borrower or reasonably related thereto or have a material change in its ownership (other than the sale of Borrowers equity securities in a public offering
or to venture capital investors) of greater than 30% or if any of David Carter, Pamela Contag, Ph.D., Anthony F. Purchio, Ph.D., Kevin Birtchnell, ACA cease to be an employee or director, as applicable, of Borrower and a qualified replacement is not
appointed within 90 days. Borrower agrees to promptly notify Bank if any of the above mentioned individuals ceases to be an employee or director of Borrower. Borrower will not, without at least 30 days prior written notice, relocate its chief
executive office or add any new offices or business locations.



7.3 Mergers or Acquisitions.



Merge or consolidate, or permit any of its Subsidiaries to merge or consolidate, with any other Person, or acquire, or permit any of its Subsidiaries to acquire, all or substantially all of the capital stock or property of another Person,
except where (i) the aggregate of such transactions



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do not in the aggregate exceed $2,000,000, (ii) no Event of Default has occurred and is continuing or would result from
such action during the term of this Agreement, (iii) Borrower is the surviving entity after any such acquisition, (v) any such transaction does not result in a material reduction of Borrowers cash and cash equivalents or a material increase on
Borrowers monthly cash burn, and (vi) such transaction would not result in a decrease of more than 25% of Tangible Net Worth. A Subsidiary may merge or consolidate into another Subsidiary or into Borrower.



7.4 Indebtedness.



Create, incur, assume, or be liable for any Indebtedness, or permit any
Subsidiary to do so, other than Permitted Indebtedness.



7.5 Encumbrance.



Create, incur, or allow any Lien on any of its property, or assign or convey any right to receive income, including the sale of any Accounts, or permit any of its Subsidiaries to do so, except for Permitted Liens, or permit any Collateral
not to be subject to the first priority security interest granted here, subject to Permitted Liens.



7.6 Distributions; Investments.

Directly or indirectly acquire or own any Person, or make any Investment in any Person, other than Permitted Investments or as permitted by Section 7.3, or permit any of its Subsidiaries to do so. Pay any dividends
(other than dividends payable solely in Borrowers capital stock) or make any distribution or payment or redeem, retire or purchase any capital stock except for (i) repurchases of stock from former employees or directors of Borrower under the
terms of applicable repurchase agreements in an aggregate amount not to exceed $150,000 in the aggregate in any fiscal year, provided that no Event of Default has occurred, is continuing or would exist after giving effect to the repurchases or (ii)
the conversion by Borrower of any of its convertible securities into other securities pursuant to the terms of such convertible securities or otherwise in exchange therefor, and payments in cash for any fractional shares.



7.7 Transactions with Affiliates.



Directly or indirectly enter into or permit any material transaction with
any Affiliate, on terms less favorable to Borrower than would be obtained in an arms length transaction with a non-affiliated Person, except transactions that are in the ordinary course of Borrowers business.



7.8 Subordinated Debt.



Make or permit any payment on any Subordinated Debt, except under the terms
of the Subordinated Debt, or amend any provision (other than an amendment extending the term of any such Subordinated Debt) in any document relating to the Subordinated Debt without Banks prior written consent.



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7.9 Compliance.



Become an investment company or a company controlled by an investment company, under the Investment
Company Act of 1940 or undertake as one of its important activities extending credit to purchase or carry margin stock, or use the proceeds of any Credit Extension for that purpose; fail to meet the minimum funding requirements of ERISA, permit a
Reportable Event or Prohibited Transaction, as defined in ERISA, to occur; fail to comply with the Federal Fair Labor Standards Act or violate any other law or regulation, if the violation could reasonably be expected to have a material adverse
effect on Borrowers business or operations or would reasonably be expected to cause a Material Adverse Change, or permit any of its Subsidiaries to do so.



8. EVENTS OF DEFAULT



Any one of the following is an Event of Default:



8.1 Payment Default.



If Borrower fails to pay any of the Obligations within 3 days after their due date. During the additional period the failure to cure the default is not an
Event of Default (but no Credit Extension will be made during the cure period);



8.2 Covenant Default.



If Borrower does not perform any obligation in Section 6 or violates any covenant in Section 7 or does not perform or observe any other material term,
condition or covenant in this Agreement, any Loan Documents, or in any agreement between Borrower and Bank and as to any default under a term, condition or covenant that can be cured, has not cured the default within 10 days after it occurs, or if
the default cannot be cured within 10 days or cannot be cured after Borrowers attempts within 10 day period, and the default may be cured within a reasonable time, then Borrower has an additional period (of not more than 30 days) to attempt to
cure the default. During the additional time, the failure to cure the default is not an Event of Default (but no Credit Extensions will be made during the cure period);



8.3 Material Adverse Change.



If there (i) occurs a material adverse change in the business operations, or condition (financial or otherwise) of the
Borrower; or (ii) is a material impairment of the prospect of repayment of any portion of the Obligations; or (iii) is a material impairment of the value or priority of Banks security interests in the Collateral.



8.4 Attachment.



If any material portion of Borrowers assets is attached, seized,
levied on, or comes into possession of a trustee or receiver and the attachment, seizure or levy is not removed in 15 Business Days, or if Borrower is enjoined, restrained, or prevented by court order from conducting a material part of its business
or if a judgment or other claim becomes a Lien on a



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material portion of Borrowers assets, or if a notice of lien, levy, or assessment is filed against any of
Borrowers assets by any government agency and not paid within 15 Business Days after Borrower receives notice. These are not Events of Default if stayed or if a bond is posted pending contest by Borrower (but no Credit Extensions will be made
during the cure period);



8.5
Insolvency.



If Borrower becomes insolvent or if
Borrower begins an Insolvency Proceeding or an Insolvency Proceeding is begun against Borrower and not dismissed or stayed within 45 days (but no Credit Extensions will be made before any Insolvency Proceeding is dismissed);



8.6 Other Agreements.



If there is a default in any agreement between Borrower and a third party
that gives the third party the right to accelerate any Indebtedness exceeding $100,000 or that could cause a Material Adverse Change, except for any events of default under the GATX Facility but only so long as: (i) such events of default are cured
on or before October 15, 2003 or (ii) the GATX Facility is paid in full and the related Loan and Security Agreements terminated on or before October 15, 2003.



8.7 Judgments.



If a money judgment(s) in the aggregate of at least $150,000 is rendered against Borrower and is unsatisfied and unstayed for 10 days (but no Credit
Extensions will be made before the judgment is stayed or satisfied);



8.8 Misrepresentations.



If Borrower or any Person acting for Borrower makes any material misrepresentation or material misstatement now or later in any warranty or representation in this Agreement or in any communication delivered to Bank or to induce Bank to
enter this Agreement or any Loan Document; or



8.9 Guaranty.



Any guaranty of any Obligations
ceases for any reason to be in full force or any Guarantor does not perform any obligation under any guaranty of the Obligations, or any material misrepresentation or material misstatement exists now or later in any warranty or representation in any
guaranty of the Obligations or in any certificate delivered to Bank in connection with the guaranty, or any circumstance described in Sections 8.4, 8.5 or 8.7 occurs to any Guarantor.



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9. BANKS RIGHTS AND REMEDIES



9.1 Rights and Remedies.



When an Event of Default occurs and continues Bank may, without notice or
demand, do any or all of the following:



(a) Declare all
Obligations immediately due and payable (but if an Event of Default described in Section 8.5 occurs all Obligations are immediately due and payable without any action by Bank);



(b) Stop advancing money or extending credit for Borrowers benefit under this Agreement or under any other agreement
between Borrower and Bank;



(c) Settle or adjust disputes and
claims directly with account debtors for amounts, on terms and in any order that Bank considers advisable;



(d) Make any payments and do any acts it considers necessary or reasonable to protect its security interest in the Collateral. Borrower will assemble the
Collateral if Bank requires and make it available as Bank designates. Bank may enter premises where the Collateral is located, take and maintain possession of any part of the Collateral, and pay, purchase, contest, or compromise any Lien which
appears to be prior or superior to its security interest and pay all expenses incurred. Borrower grants Bank a license to enter and occupy any of its premises, without charge, to exercise any of Banks rights or remedies;



(e) Bank may place a hold on any account maintained with Bank and
deliver a notice of exclusive control, any entitlement order, or other directions or instructions pursuant to any control agreement or similar agreements providing control of any Collateral.



(f) Apply to the Obligations any (i) balances and deposits of Borrower it
holds, or (ii) any amount held by Bank owing to or for the credit or the account of Borrower;



(g) Ship, reclaim, recover, store, finish, maintain, repair, prepare for sale, advertise for sale, and sell the Collateral. Bank is granted a non-exclusive, royalty-free license or other right to use, without charge,
Borrowers labels, Patents, Copyrights, Mask Works, rights of use of any name, trade secrets, trade names, Trademarks, service marks, and advertising matter, or any similar property as it pertains to the Collateral, in completing production of,
advertising for sale, and selling any Collateral and, in connection with Banks exercise of its rights under this Section, Borrowers rights under all licenses and all franchise agreements inure to Banks benefit; and



(h) Dispose of the Collateral according to the Code.



9.2 Power of Attorney.



Effective only when an Event of Default occurs and continues, Borrower
irrevocably appoints Bank as its lawful attorney to: (i) endorse Borrowers name on any checks or other forms of payment or security; (ii) sign Borrowers name on any invoice or bill of lading for any



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Account or drafts against account debtors, (iii) make, settle, and adjust all claims under Borrowers insurance
policies; (iv) settle and adjust disputes and claims about the Accounts directly with account debtors, for amounts and on terms Bank determines reasonable; and (v) transfer the Collateral into the name of Bank or a third party as the Code permits.
Bank may exercise the power of attorney to sign Borrowers name on any documents necessary to perfect or continue the perfection of any security interest regardless of whether an Event of Default has occurred. Banks appointment as
Borrowers attorney in fact, and all of Banks rights and powers, coupled with an interest, are irrevocable until all Obligations have been fully repaid and performed and Banks obligation to provide Credit Extensions terminates.



9.3 Accounts Collection.



When an Event of Default occurs and continues, Bank may notify any Person
owing Borrower money of Banks security interest in the funds and verify the amount of the Account. Upon the occurrence and during the continuance of an Event of Default, Borrower must collect all payments in trust for Bank and, if requested by
Bank, immediately deliver the payments to Bank in the form received from the account debtor, with proper endorsements for deposit.



9.4 Bank Expenses.



If Borrower fails to pay any amount or furnish any required proof of payment to third persons, Bank may make all or part of the payment or obtain
insurance policies required in Section 6.5, and take any action under the policies Bank deems prudent. Any amounts paid by Bank are Bank Expenses and immediately due and payable, bearing interest at the then applicable rate and secured by the
Collateral. No payments by Bank are deemed an agreement to make similar payments in the future or Banks waiver of any Event of Default.



9.5 Banks Liability for Collateral.



If Bank complies with reasonable banking practices and Section 9-207 of the Code, it is not liable for: (a) the safekeeping
of the Collateral; (b) any loss or damage to the Collateral; (c) any diminution in the value of the Collateral; or (d) any act or default of any carrier, warehouseman, bailee, or other person. Borrower bears all risk of loss, damage or destruction
of the Collateral.



9.6 Remedies
Cumulative.



Banks rights and remedies under this
Agreement, the Loan Documents, and all other agreements are cumulative. Bank has all rights and remedies provided under the Code, by law, or in equity. Banks exercise of one right or remedy is not an election, and Banks waiver of any
Event of Default is not a continuing waiver. Banks delay is not a waiver, election, or acquiescence. No waiver is effective unless signed by Bank and then is only effective for the specific instance and purpose for which it was given.



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9.7 Demand Waiver.



Borrower waives demand, notice of default or dishonor, notice of payment and nonpayment, notice of any default, nonpayment
at maturity, release, compromise, settlement, extension, or renewal of accounts, documents, instruments, chattel paper, and guarantees held by Bank on which Borrower is liable.



10. NOTICES



All notices or demands by any party about this Agreement or any other related agreement must be in writing and be personally
delivered or sent by an overnight delivery service, by certified mail, postage prepaid, return receipt requested, or by telefacsimile to the addresses set forth at the beginning of this Agreement. A party may change its notice address by giving the
other party written notice.



11. CHOICE OF
LAW , VENUE AND JURY TRIAL WAIVER



California law governs
the Loan Documents without regard to principles of conflicts of law. Borrower and Bank each submit to the exclusive jurisdiction of the State and Federal courts in Santa Clara County, California.



BORROWER AND BANK EACH WAIVE THEIR RIGHT TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION
ARISING OUT OF ANY OF THE LOAN DOCUMENTS OR ANY CONTEMPLATED TRANSACTION, INCLUDING CONTRACT, TORT, BREACH OF DUTY AND ALL OTHER CLAIMS. THIS WAIVER IS A MATERIAL INDUCEMENT FOR BOTH PARTIES TO ENTER INTO THIS AGREEMENT. EACH PARTY HAS REVIEWED THIS
WAIVER WITH ITS COUNSEL.



12. GENERAL
PROVISIONS



12.1 Successors and
Assigns.



This Agreement binds and is for the benefit of
the successors and permitted assigns of each party. Borrower may not assign this Agreement or any rights under it without Banks prior written consent which may be granted or withheld in Banks discretion. Bank has the right, without the
consent of or notice to Borrower, to sell, transfer, negotiate, or grant participation in all or any part of, or any interest in, Banks obligations, rights and benefits under this Agreement.



12.2 Indemnification.



Borrower will indemnify, defend and hold harmless Bank and its officers,
employees, and agents against: (a) all obligations, demands, claims, and liabilities asserted by any other party in connection with the transactions contemplated by the Loan Documents, except for obligations, demands, claims, and liabilities caused
by Banks gross negligence or willful misconduct; and (b) all losses or Bank Expenses incurred, or paid by Bank from, following, or consequential to transactions between Bank and Borrower (including reasonable attorneys fees and expenses),
except for losses and Bank Expenses caused by Banks gross negligence or willful misconduct.



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12.3 Time of Essence.



Time is of the essence for the performance of all obligations in this
Agreement.



12.4 Severability of
Provision.



Each provision of this Agreement is severable
from every other provision in determining the enforceability of any provision.



12.5 Amendments in Writing, Integration.



All amendments to this Agreement must be in writing and signed by Borrower and Bank. This Agreement represents the entire agreement about this subject
matter, and supersedes prior negotiations or agreements. All prior agreements, understandings, representations, warranties, and negotiations between the parties about the subject matter of this Agreement merge into this Agreement and the Loan
Documents.



12.6 Counterparts.



This Agreement may be executed in any number of counterparts
and by different parties on separate counterparts, each of which, when executed and delivered, are an original, and all taken together, constitute one Agreement.



12.7 Survival.



All covenants, representations and warranties made in this Agreement continue in full force while any Obligations remain
outstanding. The obligations of Borrower in Section 12.2 to indemnify Bank will survive until all statutes of limitations for actions that may be brought against Bank have run.



12.8 Confidentiality.



In handling any confidential information, Bank will exercise the same degree of care that it exercises for its own
proprietary information, but disclosure of information may be made (i) to Banks subsidiaries or affiliates in connection with their present or prospective business relations with Borrower, (ii) to prospective transferees or purchasers of any
interest in the loans, (iii) as required by law, regulation, subpoena, or other order, (iv) as required in connection with Banks examination or audit and (v) as Bank considers appropriate in exercising remedies under this Agreement.
Confidential information does not include information that either: (a) is in the public domain or in Banks possession when disclosed to Bank, or becomes part of the public domain after disclosure to Bank; or (b) is disclosed to Bank by a third
party, if Bank does not know that the third party is prohibited from disclosing the information.



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12.9 Attorneys Fees, Costs and Expenses.



In any action or proceeding between Borrower and Bank arising out of the
Loan Documents, the prevailing party will be entitled to recover its reasonable attorneys fees and other reasonable costs and expenses incurred, in addition to any other relief to which it may be entitled.



13. DEFINITIONS



13.1 Definitions.



In this Agreement:



Accounts are all existing and later arising accounts,
contract rights, and other obligations owed Borrower in connection with its sale or lease of goods (including licensing software and other technology) or provision of services, all credit insurance, guaranties, other security and all merchandise
returned or reclaimed by Borrower and Borrowers Books relating to any of the foregoing.



Advance or Advances is a loan advance (or advances) under the Committed Revolving Line.



Affiliate of a Person is a Person that owns or controls directly or indirectly the Person, any Person that controls or is controlled by
or is under common control with the Person, and each of that Persons senior executive officers, directors, partners and, for any Person that is a limited liability company, that Persons managers and members.



Bank Expenses are all audit fees and expenses and
reasonable costs and expenses (including reasonable attorneys fees and expenses) for preparing, negotiating, administering, defending and enforcing the Loan Documents (including appeals or Insolvency Proceedings).



Borrowers Books are all Borrowers books and
records including ledgers, records regarding Borrowers assets or liabilities, the Collateral, business operations or financial condition and all computer programs or discs or any equipment containing the information.



Business Day is any day that is not a Saturday, Sunday or
a day on which the Bank is closed.



Closing
Date is the date of this Agreement.



Code is the California Uniform Commercial Code as amended, revised and supplemented from time to time.



Collateral is the property described on Exhibit A.



Committed Revolving Line is an Advance of up to $3,000,000.



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Contingent Obligation is, for any Person, any direct or indirect liability, contingent
or not, of that Person for (i) any indebtedness, lease, dividend, letter of credit or other obligation of another such as an obligation directly or indirectly guaranteed, endorsed, co-made, discounted or sold with recourse by that Person, or for
which that Person is directly or indirectly liable; (ii) any obligations for undrawn letters of credit for the account of that Person; and (iii) all obligations from any interest rate, currency or commodity swap agreement, interest rate cap or
collar agreement, or other agreement or arrangement designated to protect a Person against fluctuation in interest rates, currency exchange rates or commodity prices; but Contingent Obligation does not include endorsements in the
ordinary course of business. The amount of a Contingent Obligation is the stated or determined amount of the primary obligation for which the Contingent Obligation is made or, if not determinable, the maximum reasonably anticipated liability for it
determined by the Person in good faith; but the amount may not exceed the maximum of the obligations under the guarantee or other support arrangement.



Copyrights are all copyright rights, applications or registrations and like protections in each work or authorship or derivative work,
whether published or not (whether or not it is a trade secret) now or later existing, created, acquired or held.



Credit Extension is each Advance or any other extension of credit by Bank for Borrowers benefit.



Deferred Revenue is all amounts received in advance of
performance under a contract and not yet recognized as revenue.



Eligible Accounts are Accounts in the ordinary course of Borrowers business that meet all Borrowers representations and warranties in Section 5; but Bank may change eligibility standards by giving
Borrower notice. Unless Bank agrees otherwise in writing, Eligible Accounts will not include:



(a) Accounts that the account debtor has not paid within 90 days of invoice date;



(b) Accounts for an account debtor, 50% or more of whose Accounts have not been paid within 90 days of invoice date;



(c) Credit balances over 90 days from invoice date;



(d) Accounts for an account debtor, including Affiliates, whose total
obligations to Borrower exceed 25% of all Accounts, for the amounts that exceed that percentage, unless the Bank approves in writing;



(e) Accounts for which the account debtor does not have its principal place of business in the United States;



(f) Accounts for which the account debtor is a federal, state or local
government entity or any department, agency, or instrumentality;



17



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(g) Accounts for which Borrower owes the account debtor, but only up to the amount owed (sometimes called
contra accounts, accounts payable, customer deposits or credit accounts);



(h) Accounts for demonstration or promotional equipment, or in which goods are consigned, sales guaranteed, sale or return, sale on approval, bill and hold, or other terms if account debtors payment may be
conditional;



(i) Accounts for which the account debtor is
Borrowers Affiliate, officer, employee, or agent;



(j)
Accounts in which the account debtor disputes liability or makes any claim and Bank believes there may be a basis for dispute (but only up to the disputed or claimed amount), or if the Account Debtor is subject to an Insolvency Proceeding, or
becomes insolvent, or goes out of business;



(k) Accounts which
respect to which the goods giving rise to such Accounts have not been shipped and billed to the account debtor, the services giving rise to such Account have not been performed and accepted by the account debtor, or the Account does not otherwise
represent a final sale;



(l) Accounts that represent progress
payments or other advance billings that are due prior to the completion of performance by Borrower of the subject contract for goods or services; and



(m) Accounts for which Bank reasonably determines collection to be doubtful.



Equipment is all present and future machinery, equipment, tenant improvements, furniture, fixtures,
vehicles, tools, parts and attachments in which Borrower has any interest.



ERISA is the Employment Retirement Income Security Act of 1974, and its regulations.



GAAP is generally accepted accounting principles.



GATX Facilitymeans the credit accommodations made by GATX Ventures, Inc. under that certain Loan and
Security Agreement, dated as of .



Guarantor is any present or future guarantor of the Obligations.



Indebtedness is (a) indebtedness for borrowed money or the deferred price of property or services, such
as reimbursement and other obligations for surety bonds and letters of credit, (b) obligations evidenced by notes, bonds, debentures or similar instruments, (c) capital lease obligations and (d) Contingent Obligations.



Insolvency Proceeding are proceedings by or against any
Person under the United States Bankruptcy Code, or any other bankruptcy or insolvency law, including assignments for the benefit of creditors, compositions, extensions generally with its creditors, or proceedings seeking reorganization, arrangement,
or other relief.



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Intellectual Property is:



(a) Copyrights, Trademarks, and Patents including amendments, renewals,
extensions, and all licenses or other rights to use and all license fees and royalties from the use;



(b) Any trade secrets and any intellectual property rights in computer software and computer software products now or later existing, created, acquired or
held;



(c) All design rights which may be available to Borrower
now or later created, acquired or held;



(d) Any claims for
damages (past, present or future) for infringement of any of the rights above, with the right, but not the obligation, to sue and collect damages for use or infringement of the intellectual property rights above;



All proceeds and products of the foregoing, including all insurance,
indemnity or warranty payments.



Inventory
is present and future inventory in which Borrower has any interest, including merchandise, raw materials, parts, supplies, packing and shipping materials, work in process and finished products intended for sale or lease or to be furnished under a
contract of service, of every kind and description now or later owned by or in the custody or possession, actual or constructive, of Borrower, including inventory temporarily out of its custody or possession or in transit and including returns on
any accounts or other proceeds (including insurance proceeds) from the sale or disposition of any of the foregoing and any documents of title.



Investment is any beneficial ownership of (including stock, partnership interest or other securities) any Person, or any loan, advance
or capital contribution to any Person.



Lien
is a mortgage, lien, deed of trust, charge, pledge, security interest or other encumbrance.



Loan Documents are, collectively, this Agreement, any note, or notes or guaranties executed by Borrower or Guarantor, and any other present or future agreement between Borrower and/or for the
benefit of Bank in connection with this Agreement, all as amended, extended or restated.



Material Adverse Change is defined in Section 8.3.



Obligations are debts, principal, interest, Bank Expenses and other amounts Borrower owes Bank now or later, including cash management
services, letters of credit and foreign exchange contracts, if any and including interest accruing after Insolvency Proceedings begin and debts, liabilities, or obligations of Borrower assigned to Bank.



19



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Patents are patents, patent applications and like protections, including improvements,
divisions, continuations, renewals, reissues, extensions and continuations-in-part of the same.



Permitted Indebtedness is:



(a) Borrowers indebtedness to Bank under this Agreement or any other Loan Document;



(b) Indebtedness existing on the Closing Date and shown on the Schedule;



(c) Subordinated Debt;



(d) Indebtedness to trade creditors incurred in the ordinary course of
business;



(e) Indebtedness secured by Permitted Liens;



(f) Indebtedness of Borrower to any Subsidiary and Contingent
Obligations of any Subsidiary with respect to obligations of Borrower (provided that the primary obligations are not prohibited hereby), and Indebtedness of any Subsidiary to any other Subsidiary and Contingent Obligations of any Subsidiary with
respect to obligations of any other Subsidiary (provided that the primary obligations are not prohibited hereby);



(g) Other Indebtedness not otherwise permitted by Section 7.4 not exceeding One Hundred Fifty Thousand Dollars ($150,000) in the aggregate outstanding at
any time; and



(h) Extensions, refinancings, modifications,
amendments and restatements of any items of Permitted Indebtedness (a) through (f) above, provided that the principal amount thereof is not increased or the terms thereof are not modified to impose more burdensome terms upon Borrower or its
Subsidiary, as the case may be.



Permitted
Investments are:



(a) Investments shown on the
Schedule and existing on the Closing Date;



(b) Marketable
direct obligations issued or unconditionally guaranteed by the United States or its agency or any State maturing within 1 year from its acquisition, (ii) commercial paper maturing no more than 1 year after its creation and having the highest rating
from either Standard & Poors Corporation or Moodys Investors Service, Inc., and (iii) Banks certificates of deposit issued maturing no more than 1 year after issue,and (iv) any Investments permitted by Borrowers
investment policy, as amended from time to time, provided that such investment policy (and any such amendment thereto) has been approved by Bank;



(c) Investments consisting of the endorsement of negotiable instruments for deposit or collection or similar transactions in the ordinary course of
Borrower;



(d) Investments accepted in connection with
Transfers permitted by Section 7.1;



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(e) Investments of Subsidiaries in or to other Subsidiaries or Borrower and Investments by Borrower in
Subsidiaries not to exceed $250,000 in the aggregate in any fiscal year;



(f) Investments consisting of (i) travel advances and employee relocation loans and other employee loans and advances in the ordinary course of business not to exceed $250,000 in any one fiscal year or $300,000 at any
one time outstanding, and (ii) loans to employees, officers or directors relating to the purchase of equity securities of Borrower or its Subsidiaries pursuant to employee stock purchase plans or agreements approved by Borrowers Board of
Directors;



(g) Investments (including debt obligations)
received in connection with the bankruptcy or reorganization of customers or suppliers and in settlement of delinquent obligations of, and other disputes with, customers or suppliers arising in the ordinary course of business;



(h) Investments consisting of notes receivable of, or prepaid royalties and
other credit extensions, to customers and suppliers who are not Affiliates, in the ordinary course of business; provided that this paragraph (h) shall not apply to Investments of Borrower in any Subsidiary;



(i) Investments pursuant to investment policy guidelines approved by
Borrowers Board of Directors and Bank set forth Exhibit E hereto; and



(j) Joint ventures or strategic alliances in the ordinary course of Borrowers business consisting of the non-exclusive licensing of technology, the development of technology or the providing of technical
support, provided that any cash investments by Borrower do not exceed $50,000 in the aggregate in any fiscal year.



Permitted Liens are:



(a) Liens existing on the Closing Date and shown on the Schedule or arising under this Agreement or other Loan Documents;



(b) Liens for taxes, fees, assessments or other government charges or levies,
either not delinquent or being contested in good faith and for which Borrower maintains adequate reserves on its Books, if they have no priority over any of Banks security interests;



(c) Purchase money Liens (i) on Equipment acquired or held by Borrower or its
Subsidiaries incurred for financing the acquisition of the Equipment, or (ii) existing on equipment when acquired, if the Lien is confined to the property and improvements and the proceeds of the equipment;



(d) Licenses or sublicenses granted in the ordinary course of Borrowers
business and any interest or title of a licensor or under any license or sublicense;



(e) Leases or subleases granted in the ordinary course of Borrowers business, including in connection with Borrowers leased premises or leased property;



21



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(f) Liens incurred in the extension, renewal or refinancing of the indebtedness secured by Liens
described in (a) through (c), but any extension, renewal or replacement Lien must be limited to the property encumbered by the existing Lien and the principal amount of the indebtedness may not increase;



(g) Liens arising from judgments, decrees or attachments in circumstances not
constituting an Event of Default under Section 8.4 or 8.7;



(h)
Liens in favor of other financial institutions arising in connection with Borrowers deposit accounts held at such institutions, provided that Bank has a perfected security interest in the amounts held in such deposit accounts;



(i) carriers, warehousemens, mechanics,
materialmens, repairmens or other like Liens arising in the ordinary course of business which are not overdue for a period of more than 30 days or which are being contested in good faith and by appropriate proceedings if adequate
reserves with respect thereto are maintained on the books of the applicable Person;



(j) Liens to secure payment of workers compensation, employment insurance, old age pensions, social security or other like obligations incurred in the ordinary course of business;



(k) easements, rights-of-way, restrictions and other similar encumbrances
affecting real property which, in the aggregate, are not substantial in amount, and which do not in any case materially detract from the value of the property subject thereto or materially interfere with the ordinary conduct of the business of the
applicable Person; and



(l) Liens in favor of customs and
revenue authorities arising as a matter of law to secure payment of customs duties in connection with the importation of goods.



Person is any individual, sole proprietorship, partnership, limited liability company, joint venture, company association, trust,
unincorporated organization, association, corporation, institution, public benefit corporation, firm, joint stock company, estate, entity or government agency.



Prime Rate is Banks most recently announced prime rate, even if it is not Banks lowest rate.



ResponsibleOfficer is each of the Chief Executive
Officer, the President, the Chief Financial Officer and the Controller of Borrower.



Revolving Maturity Date is September 9, 2005.



Schedule is any attached schedule of exceptions.



Subordinated Debt is debt incurred by Borrower subordinated to Borrowers indebtedness owed to Bank
and which is reflected in a written agreement in a manner and form acceptable to Bank and approved by Bank in writing.



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Subsidiary is for any Person, or any other business entity of which more than 50% of
the voting stock or other equity interests is owned or controlled, directly or indirectly, by the Person or one or more Affiliates of the Person.



Tangible Net Worth is, on any date, the consolidated total assets of Borrower and its Subsidiaries minus, (i) any amounts
attributable to (a) goodwill, (b) intangible items such as unamortized debt discount and expense, Patents, trade and service marks and names, Copyrights and research and development expenses except prepaid expenses, and (c) reserves not already
deducted from assets, and (ii) Total Liabilities.



TotalLiabilities is on any day, obligations that should, under GAAP, be classified as liabilities on Borrowers consolidated balance sheet, including all Indebtedness, and current portion Subordinated Debt
allowed to be paid, but excluding all other Subordinated Debt.



Trademarks are trademark and servicemark rights, registered or not, applications to register and registrations and like protections, and the entire goodwill of the business of Assignor connected with the
trademarks.



|                    |  |                    
|------------------- |  | -------------------
|BORROWER:          
|                   
|XENOGEN CORPORATION
|                    | 
|By:                 |  | /s/ David W. Carter
|Title:              |  | CEO                
|                   
|BANK:              
|                   
|SILICON VALLEY BANK
|                    | 
|By:                 |  | /s/ Tim Walsh      
|Title:              |  | Senior VP          



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EXHIBIT A



The Collateral consists of all of Borrowers right, title and interest in and to the following:



All goods and equipment now owned or hereafter acquired, including, without
limitation, all machinery, fixtures, vehicles (including motor vehicles and trailers), and any interest in any of the foregoing, and all attachments, accessories, accessions, replacements, substitutions, additions, and improvements to any of the
foregoing, wherever located;



All inventory, now owned or
hereafter acquired, including, without limitation, all merchandise, raw materials, parts, supplies, packing and shipping materials, work in process and finished products including such inventory as is held for sale or lease, or to be furnished under
a contract of service or is temporarily out of Borrowers custody or possession or in transit and including any returns or repossession upon any accounts or other proceeds, including insurance proceeds, resulting from the sale or disposition of
any of the foregoing and any documents of title representing any of the above;



All contract rights and general intangibles now owned or hereafter acquired, including, without limitation, goodwill, trademarks, servicemarks, trade styles, trade names, patents, patent applications, leases, license
agreements, franchise agreements, blueprints, drawings, purchase orders, customer lists, route lists, infringements, claims, computer programs, computer discs, computer tapes, literature, reports, catalogs, design rights, income tax refunds,
payments of insurance, payment intangibles, and rights to payment of any kind;



All now existing and hereafter arising accounts (including health-care insurance receivables), contract rights, royalties, license rights and all other forms of obligations owing to Borrower arising out of the sale or
lease of goods, the licensing of technology or the rendering of services by Borrower, whether or not earned by performance, and any and all credit insurance, guaranties, and other security therefor, as well as all merchandise returned to or
reclaimed by Borrower;



All documents (including negotiable
documents), cash, deposit accounts, securities, securities entitlements, securities accounts, investment property, financial assets, letters of credit, letter of credit rights, money, certificates of deposit, instruments (including promissory notes)
and chattel paper (including tangible and electronic chattel paper) now owned or hereafter acquired and Borrowers Books relating to the foregoing;



All copyright rights, copyright applications, copyright registrations and like protections in each work of authorship and derivative work thereof, whether
published or unpublished, now owned or hereafter acquired; all trade secret rights, including all rights to unpatented inventions, know-how, operating manuals, license rights and agreements and confidential information, now owned or hereafter
acquired; all claims for damages by way of any past, present and future infringement of any of the foregoing; and



All Borrowers Books relating to the foregoing, and the computers and equipment containing said books and records, and any and all claims, rights and
interests in any of the above and all substitutions for, additions and accessions to and proceeds thereof.



Notwithstanding the foregoing, the Collateral shall not be deemed to include any copyrights, copyright applications, copyright registration and like
protection in each work of authorship and derivative work thereof, whether published or unpublished, now owned or hereafter acquired; any patents, patent applications and like



Exhibit A - 1



---

protections including without limitation improvements, divisions, continuations, renewals, reissues, extensions and
continuations-in-part of the same, trademarks, servicemarks and applications therefor, whether registered or not, and the goodwill of the business of Borrower connected with and symbolized by such trademarks, any trade secret rights, including any
rights to unpatented inventions, know-how, operating manuals, license rights and agreements and confidential information, now owned or hereafter acquired; or any claims for damage by way of any past, present and future infringement of any of the
foregoing (collectively, the Intellectual Property), except that the Collateral shall include the proceeds of all the Intellectual Property that are accounts, (i.e. accounts receivable) of Borrower, or general intangibles consisting of
rights to payment, if a judicial authority (including a U.S. Bankruptcy Court) holds that a security interest in the underlying Intellectual Property is necessary to have a security interest in such accounts and general intangibles of Borrower that
are proceeds of the Intellectual Property, then the Collateral shall automatically, and effective as of the Closing Date, include the Intellectual Property to the extent necessary to permit perfection of Banks security interest in such
accounts and general intangibles of Borrower that are proceeds of the Intellectual Property.



Notwithstanding anything contained in this paragraph, the term Collateral shall not include any property that is subject to a Lien that is otherwise permitted pursuant to paragraph (c) of the definition of
Permitted Liens.



2



---

EXHIBIT B



LOAN PAYMENT/ADVANCE TELEPHONE REQUEST FORM



DEADLINE FOR SAME DAY PROCESSING IS 12:00 NOON, P.S.T.



|                                    |  |       |  | 
|----------------------------------- |  | ----- |  | 
|TO: CENTRAL CLIENT SERVICE DIVISION |  | DATE: |  | 
|                                    |  |      
|FAX#: (408) 496-2426                |  | TIME: |  | 



|                          |  |                       
|------------------------- |  | ----------------------
|FROM: XENOGEN CORPORATION
|                          |  | CLIENT NAME (BORROWER)



|                      |  |                         
|--------------------- |  | ------------------------
|REQUESTED BY:        
|                      |  | AUTHORIZED SIGNERS NAME
|                     
|AUTHORIZED SIGNATURE:



|               |  |             
|-------------- |  | ------------
|PHONE NUMBER: 
|               | 
|FROM ACCOUNT # |  | TO ACCOUNT #



|                                 |  |                        
|-------------------------------- |  | -----------------------
|REQUESTED TRANSACTION TYPE       |  | REQUESTED DOLLAR AMOUNT
|PRINCIPAL INCREASE (ADVANCE)     |  | $                      
|PRINCIPAL PAYMENT (ONLY)         |  | $                      
|INTEREST PAYMENT (ONLY)          |  | $                      
|PRINCIPAL AND INTEREST (PAYMENT) |  | $                      
|                                 | 
|OTHER INSTRUCTIONS:              |  |                        



All Borrowers representations
and warranties in the Loan and Security Agreement are true, correct and complete in all material respects on the date of the telephone request for and Advance confirmed by this Borrowing Certificate; but those representations and warranties
expressly referring to another date shall be true, correct and complete in all material respects as of that date.



BANK USE ONLY



TELEPHONE REQUEST:



The following person is authorized to
request the loan payment transfer/loan advance on the advance designated account and is known to me.



|                                                |  |                                                
|----------------------------------------------- |  | -----------------------------------------------
|_______________________________________________ |  | _______________________________________________
|Authorized Requester                            |  | Phone #                                        
|                                                | 
|_______________________________________________ |  | _______________________________________________
|Received By (Bank)                              |  | Phone #                                        
|                                               
|_______________________________________________
|Authorized Signature (Bank)                    



Exhibit B - 1



---

EXHIBIT C



ELIGIBLE ACCOUNTS CERTIFICATE



|         |  |                                                                   |  |       |  |                                                            
|-------- |  | ----------------------------------------------------------------- |  | ----- |  | -----------------------------------------------------------
|Borrower |  | Xenogen Corporation 860 Atlantic Avenue Alameda, California 94501 |  | Bank: |  | Silicon Valley Bank 3003 Tasman Drive Santa Clara, CA 95054



|                                                     |  |                                        |  |   |  |  |   | 
|---------------------------------------------------- |  | -------------------------------------- |  | - |  |  | - | 
|ACCOUNTS RECEIVABLE                                  |  |                                        |  |   |  | 
|1.                                                   |  | Accounts Receivable Book Value as of   |  |   |  |  | $ | 
|2.                                                   |  | Additions (please explain on reverse)  |  |   |  |  | $ | 
|3.                                                   |  | TOTAL ACCOUNTS RECEIVABLE              |  |   |  |  | $ | 
|                                                     |  |                                       
|ACCOUNTS RECEIVABLE DEDUCTIONS (without duplication) |  |                                        |  |   |  | 
|4.                                                   |  | Amounts over 90 days due               |  | $ |  |  |   | 
|5.                                                   |  | Balance of 50% over 90 day accounts    |  | $ |  |  |   | 
|6.                                                   |  | Credit balances over 90 days           |  | $ |  |  |   | 
|7.                                                   |  | Concentration Limits                   |  | $ |  |  |   | 
|8.                                                   |  | Foreign Accounts                       |  | $ |  |  |   | 
|9.                                                   |  | Governmental Accounts                  |  | $ |  |  |   | 
|10.                                                  |  | Contra Accounts                        |  | $ |  |  |   | 
|11.                                                  |  | Promotion or Demo Accounts             |  | $ |  |  |   | 
|12.                                                  |  | Intercompany/Employee Accounts         |  | $ |  |  |   | 
|13.                                                  |  | Undelivered Goods or Services          |  | $ |  |  |   | 
|14.                                                  |  | Progress Payments and Advance Billings |  | $ |  |  |   | 
|15.                                                  |  | Other (please explain on reverse)      |  | $ |  |  |   | 
|16.                                                  |  | TOTAL ACCOUNTS RECEIVABLE DEDUCTIONS   |  |   |  |  | $ | 
|17.                                                  |  | Eligible Accounts (#3 minus #16)       |  | $ |  |  |   | 



The undersigned represents and
warrants that this is true, complete and correct, and that the information in this Eligible Accounts Certificate complies with the representations and warranties in the Loan and Security Agreement between the undersigned and Silicon Valley Bank.



|                    |  |                                                        |  |                                                         |  | 
|------------------- |  | ------------------------------------------------------ |  | ------------------------------------------------------- |  | 
|COMMENTS:           |  | BANK USE ONLY                                         
|                    |  |                                                        |  |                                                        
|                    |  |                                                        |  |                                                         |  | 
|XENOGEN CORPORATION |  | Recd By    __________________________________________
|                    |  |                                                        |  | Authorized
Signer                                      
|By:                 |  |                                                        |  | Date:    __________________________________________    
|                    |  |                                                       
|                    |  |                                                        |  | Verified:    __________________________________________
|                    |  |                                                        |  | Authorized
Signer                                      
|                    |  |                                                        |  | Date:    __________________________________________    



Exhibit C - 1



---

EXHIBIT D

COMPLIANCE CERTIFICATE



|      |  |                          
|----- |  | -------------------------
|TO:   |  | SILICON VALLEY BANK      
|      |  | 3003 Tasman Drive        
|      |  | Santa Clara, CA 95054    
|      | 
|FROM: |  | XENOGEN CORPORATION      
|      |  | 860 Atlantic Avenue      
|      |  | Alameda, California 94501



The undersigned
authorized officer of Xenogen Corporation (Borrower) certifies that under the terms and conditions of the Loan and Security Agreement between Borrower and Bank (the Agreement), (i) Borrower is in complete compliance for the
period ending  with all required covenants except as noted below and (ii) all representations and
warranties in the Agreement are true and correct in all material respects on this date. Attached are the required documents supporting the certification. The Officer certifies that these are prepared in accordance with Generally Accepted Accounting
Principles (GAAP) consistently applied from one period to the next except as explained in an accompanying letter or footnotes. The Officer acknowledges that no borrowings may be requested at any time or date of determination that Borrower is not in
compliance with any of the terms of the Agreement, and that compliance is determined not just at the date this certificate is delivered.



Please indicate compliance status by circling Yes/No under Complies column.



|                                                                              |  |                                |  |          |  |   
|----------------------------------------------------------------------------- |  | ------------------------------ |  | -------- |  | --
|Reporting Covenant                                                            |  | Required                       |  | Complies
|Monthly financial statements + CC                                             |  | Monthly within 30 days         |  | Yes      |  | No
|Annual (Audited)                                                              |  | FYE within 120 days            |  | Yes      |  | No
|A/R, A/P Agings, Deferred Revenue Schedule, and Eligible Accounts Certificate |  | Monthly within 30 days         |  | Yes      |  | No
|Financial Projections                                                         |  | Initial and FYE within 45 days |  | Yes      |  | No
|A/R Audit                                                                     |  | Annual                         |  | Yes      |  | No



|                             |  |          |  |        |  |          |  |   
|---------------------------- |  | -------- |  | ------ |  | -------- |  | --
|Financial Covenant           |  | Required |  | Actual |  | Complies
|Maintain on a Monthly Basis: |  |          |  |        |  |          |  |   
|Minimum Quick Ratio          |  | 1.75     |  | :1.00  |  | Yes      |  | No



|                                             |  |                                                                 |  |                  
|-------------------------------------------- |  | --------------------------------------------------------------- |  | -----------------
|Comments Regarding Exceptions: See Attached. |  | BANK USE ONLY                                                  
|                                             | 
|Sincerely,                                   |  | Received by: __________________________________________________
|                                             |  |                                                                 |  | AUTHORIZED
SIGNER
|XENOGEN CORPORATION                          |  |                                                                 |  |                  
|                                             | 
|                                             |  | Date: _______________________________________________________  
|                                             | 
|SIGNATURE                                    |  | Verified: _____________________________________________________
|                                             |  |                                                                 |  | AUTHORIZED
SIGNER
|                                             | 
|TITLE                                        |  | Date: _______________________________________________________  
|                                             |  |                                                                 |  |                  
|                                             |  | Compliance Status:                                              |  | Yes        No    
|DATE                                         |  |                                                                 |  |                  



Exhibit D- 1



---

CORPORATE BORROWING RESOLUTION



|          |  |                           |  |       |  |                           
|--------- |  | ------------------------- |  | ----- |  | --------------------------
|Borrower: |  | XENOGEN CORPORATION       |  | Bank: |  | Silicon Valley Bank       
|          |  | 860 Atlantic Avenue       |  |       |  | 3003 Tasman Drive         
|          |  | Alameda, California 94501 |  |       |  | Santa Clara, CA 95054-1191



I, the Secretary or Assistant
Secretary of Xenogen Corporation (Borrower), CERTIFY that Borrower is a corporation existing under the laws of the State of Delaware.



Icertify that at a meeting of Borrowers Directors (or by other authorized corporate action) duly held the following resolutions were adopted.



It is resolved that any oneof the following officers of Borrower, whose name, title
and signature is below:



|      |  |           |  |                  
|----- |  | --------- |  | -----------------
|NAMES |  | POSITIONS |  | ACTUAL SIGNATURES
|      |  |          
|      |  |           |  |                  
|      |  |          
|      |  |           |  |                  
|      |  |          
|      |  |           |  |                  
|      |  |          
|      |  |           |  |                  



may act for Borrower and:



Borrow Money. Borrow money from Silicon Valley Bank (Bank).



Execute Loan Documents. Execute any loan documents Bank requires.



Grant Security. Grant Bank a security interest in any of
Borrowers assets.



Negotiate Items. Negotiate or discount all
drafts, trade acceptances, promissory notes, or other indebtedness in which Borrower has an interest and receive cash or otherwise use the proceeds.



Letters of Credit. Apply for letters of credit from Bank.



Foreign Exchange Contracts. Execute spot or forward foreign exchange contracts.



Issue Warrants. Issue warrants for Borrowers stock.



Further Acts. Designate other individuals to request advances, pay fees and costs and execute other documents or agreements
(including documents or agreement that waive Borrowers right to a jury trial) they think necessary to effectuate these Resolutions.



1



---

Further resolved that all acts authorized by these Resolutions and performed before they were adopted are
ratified. These Resolutions remain in effect and Bank may rely on them until Bank receives written notice of their revocation.



Icertify that the persons listed above are Borrowers officers with the titles and signatures shown following their names and that these resolutions have not
been modified are currently effective.



CERTIFIED TO AND ATTESTED BY:



|  |  |                                  
|- |  | ---------------------------------
|X |  |                                  
|  |  | *Secretary or Assistant Secretary
|  | 
|X |  |                                  

---

|* | NOTE: In case the Secretary or other certifying officer is designated by the foregoing resolutions as one of the signing officers, this resolution should also be signed by a second
Officer or Director of Borrower.
|- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



2



---

LOAN MODIFICATION AGREEMENT



This Loan Modification Agreement (this LMA) is entered into as of September 30, 2004, by and between XENOGEN
CORPORATION, a Delaware corporation (the Borrower) and SILICON VALLEY BANK (Bank).



1. DESCRIPTION OF EXISTING INDEBTEDNESS. Among other indebtedness which may be owing by Borrower to Bank, Borrower is indebted to Bank pursuant to, among other documents, a Loan and Security Agreement, dated
September 10, 2003, as may be amended from time to time, (the Loan Agreement). The Loan Agreement provides for, among other things a Committed Revolving Line in the principal amount of Seven Million Dollars ($7,000,000). Defined terms
used but not otherwise defined herein shall have the same meanings as in the Loan Agreement.



Hereinafter, all indebtedness owing by Borrower to Bank shall be referred to as the Indebtedness.



2. DESCRIPTION OF COLLATERAL AND GUARANTIES. Repayment of the Indebtedness is secured by the Collateral as described in the Loan Agreement.



Hereinafter, the above-described security documents and guaranties, together
with all other documents securing repayment of the Indebtedness shall be referred to as the Security Documents. Hereinafter, the Security Documents, together with all other documents evidencing or securing the Indebtedness shall be
referred to as the Existing Loan Documents.



3. MODIFICATIONS TO LOAN AGREEMENT.



A. Section 2.1.1(a)(i) and (ii) of the Loan Agreement are each hereby amended to read as follows:



(a) Bank will make Advances to Borrower as follows:



(i) On or prior to March 31, 2005, Bank will make Advances to Borrower not exceeding the Committed Revolving
Line.



(ii) At all times after March 31, 2005
and until the Revolving Maturity Date, Bank will make Advances not exceeding (i) the lesser of: (A) the Committed Revolving Line, minus (i) amounts deemed outstanding under the Cash Management Services Sublimit or (B)the Borrowing Base,
minus (i) amounts deemed outstanding under the Cash Management Services Sublimit.



---

B. Section 2.1.1(d) of the Loan Agreement is hereby deleted in its entirety and is no longer applicable.



C. Section 2.1.2 of the Loan Agreement is hereby amended to
read as follows:



2.1.2 Cash Management Services
Sublimit.



Borrower may use up to Two Million Dollars
($2,000,000) for Banks Cash Management Services, which may include merchant services, direct deposit of payroll, business credit card, and check cashing services identified in various cash management services agreements related to such
services (the Cash Management Services). All amounts Bank pays for any Cash Management Services will be treated as Advances under the Committed Revolving Line.



D. Section 6.2(b) of the Loan Agreement is hereby amended to read as follows:



(b) monthly, within 30 days after the last day of each month, Borrower
will deliver to Bank (i) aged listings of accounts receivable and accounts payable, a detailed Deferred Revenue Schedule, and (ii) beginning with the monthly period ending on April 30, 2005, a Borrowing Base Certificate.



E. The definition for Borrowing Base set forth in Section 13.1 of
the Loan Agreement is hereby amended to read as follows:



Borrowing Base is 80% of Eligible Accounts as of Borrowers prior fiscal quarter end as determined by Bank from Borrowers most recent Borrowing Base Certificates; provided, however, that
Bank may lower the percentage of the Borrowing Base after performing an audit of Borrowers Collateral, such percentage adjustment by Bank to be based upon Banks reasonable business judgment.



F. The definition for Equity Financing is hereby deleted from
Section 13.1 of the Loan Agreement.



G. The definition of
Threshold Event set forth in Section 13.1 of the Loan Agreement is hereby amended to read as follows:



Threshold Event is a date on which Borrowers Modified Quick Ratio has fallen below 2.00 to 1.00.



H. Exhibit D attached hereto replaces the existing Exhibit D
to the Loan Agreement.



4. CONSISTENT CHANGES. The Existing Loan
Documents are hereby amended wherever necessary to reflect the changes described above.



---

5. PAYMENT OF EXPENSES. Borrower shall pay Lender all out-of-pocket expenses relating to the drafting and
negotiation of this LMA.



6. NO DEFENSES OF BORROWER. Borrower agrees
that, as of the date hereof, it has no defenses against the obligations to pay any amounts under the Indebtedness.



7. CONTINUING VALIDITY. Borrower understands and agrees that in modifying the existing Indebtedness, Bank is relying upon Borrowers representations,
warranties, and agreements, as set forth in the Existing Loan Documents. Except as expressly modified pursuant to this LMA, the terms of the Existing Loan Documents remain unchanged and in full force and effect. Banks agreement to
modifications to the existing Indebtedness pursuant to this LMA in no way shall obligate Bank to make any future modifications to the Indebtedness. Nothing in this LMA shall constitute a satisfaction of the Indebtedness. It is the intention of Bank
and Borrower to retain as liable parties all makers and endorsers of Existing Loan Documents, unless the party is expressly released by Bank in writing. No maker, endorser, or guarantor will be released by virtue of this LMA. The terms of this
paragraph apply not only to this LMA, but also to all subsequent loan modification agreements.



8. CONDITIONS. The effectiveness of this LMA is conditioned upon payment of the expenses by Borrower.



This Loan Modification Agreement is executed as of the date first written above.



|                    |  |                         |  |        |  |                
|------------------- |  | ----------------------- |  | ------ |  | ---------------
|BORROWER:           |  | BANK:                  
|                    | 
|XENOGEN CORPORATION |  | SILICON VALLEY BANK    
|                    |  |                         | 
|By:                 |  | /s/ William A. Albright |  | By:    |  | /s/ Peter Scott
|Name:               |  | William A. Albright     |  | Name:  |  | Peter Scott    
|Title:              |  | CFO                     |  | Title: |  | SVP            



---

EXHIBIT C



BORROWING BASE CERTIFICATE



|          |  |                                                             |  |       |  |                                                              
|--------- |  | ----------------------------------------------------------- |  | ----- |  | -------------------------------------------------------------
|Borrower: |  | Xenogen Corporation 
860 Atlantic Avenue  Alameda, CA 94501 |  | Bank: |  | Silicon Valley Bank 
3003 Tasman Drive  Santa Clara, CA 95054



Commitment Amount: $7,000,000



|                                                     |  |                                                        
|---------------------------------------------------- |  | -------------------------------------------------------
|ACCOUNTS RECEIVABLE                                 
|1.                                                   |  | Accounts Receivable Book Value as of

        $        
|2.                                                   |  | Additions (please explain on reverse)
$                
|3.                                                   |  | TOTAL ACCOUNTS RECEIVABLE
$                            
|                                                    
|ACCOUNTS RECEIVABLE DEDUCTIONS (without duplication)
|4.                                                   |  | Amounts over 90 days due
$                             
|5.                                                   |  | Balance of 50% over 90 day accounts
$                  
|6.                                                   |  | Credit balances over 90 days
$                         
|7.                                                   |  | Concentration Limits
$                                 
|8.                                                   |  | Foreign Accounts
$                                     
|9.                                                   |  | Governmental Accounts         
$                       
|10.                                                  |  | Contra Accounts
$                                      
|11.                                                  |  | Promotion or Demo Accounts         
$                  
|12.                                                  |  | Intercompany/Employee Accounts
$                       
|13.                                                  |  | Undelivered Goods or Services
        $                
|14.                                                  |  | Progress Payments and Advance Billings         
$      
|15.                                                  |  | R&D Offset         
$                                  
|16.                                                  |  | Other (please explain on reverse)         
$           
|17.                                                  |  | TOTAL ACCOUNTS RECEIVABLE DEDUCTIONS         
$        
|18.                                                  |  | Eligible Accounts (#3 minus #17)         
$            
|19.                                                  |  | LOAN VALUE OF ACCOUNTS (80% of #18)         
$         
|                                                    
|BALANCES                                            
|20.                                                  |  | Maximum Loan Amount         
$                         
|21.                                                  |  | Total Funds Available [Lesser of #20 or #19]         
$
|22.                                                  |  | Present balance owing on Line of Credit         
$     
|23.                                                  |  | Outstanding under Sublimits         
$                 
|                                                     |  | RESERVE POSITION (#21 minus #22 and #23)         
$    



The undersigned represents and
warrants that this is true, complete and correct, and that the information in this Borrowing Base Certificate complies with the representations and warranties in the Loan and Security Agreement between the undersigned and Silicon Valley Bank.



---

|                    |  |                   |  |           |  |                  
|------------------- |  | ----------------- |  | --------- |  | -----------------
|COMMENTS:           |  | BANK USE ONLY    
|                    |  |                   | 
|                    |  |                   |  | Recd By  |  |                  
|                    |  |                   |  |           |  | Authorized Signer
|                    |  |                  
|XENOGEN CORPORATION |  | Date:             |  |          
|                    |  |                   | 
|                    |  |                   |  | Verified: |  |                  
|By:                 |  |                   |  |           |  | Authorized Signer
|                    |  |                   | 
|                    |  | Authorized Signer |  | Date:     |  |                  



---

EXHIBIT D



COMPLIANCE CERTIFICATE



|      |  |                          
|----- |  | -------------------------
|TO:   |  | SILICON VALLEY BANK      
|      | 
|FROM: |  | XENOGEN CORPORATION      
|      |  | 860 Atlantic Avenue      
|      |  | Alameda, California 94501



The undersigned
authorized officer of XENOGEN CORPORATION (Borrower) certifies that under the terms and conditions of the Loan and Security Agreement between Borrower and Bank (the Agreement), (i) Borrower is in complete compliance for the
period ending  with all required covenants except as noted below and (ii) all representations and warranties in the
Agreement are true and correct in all material respects on this date. In addition, the undersigned authorized officer of Borrower certifies that Borrower and each Subsidiary (i) has timely filed all required tax returns and paid, or made adequate
provision to pay, all material taxes, except those being contested in good faith with adequate reserves under GAAP and (ii) does not have any legal actions pending or threatened against Borrower or any Subsidiary which Borrower has not previously
notified in writing to Bank. Attached are the required documents supporting the certification. The Officer certifies that these are prepared in accordance with Generally Accepted Accounting Principles (GAAP) consistently applied from one period to
the next except as explained in an accompanying letter or footnotes. The Officer acknowledges that no borrowings may be requested at any time or date of determination that Borrower is not in compliance with any of the terms of the Agreement, and
that compliance is determined not just at the date this certificate is delivered.



Please indicate compliance status by circling Yes/No under Complies column.



|                                                                           |  |                                                |  |          |  |   
|-------------------------------------------------------------------------- |  | ---------------------------------------------- |  | -------- |  | --
|Reporting Covenant                                                         |  | Required                                       |  | Complies
|                                                                           |  |                                                | 
|Monthly financial statements + CC                                          |  | Monthly within 30 days                         |  | Yes      |  | No
|Annual (Audited)                                                           |  | FYE within 120 days                            |  | Yes      |  | No
|A/R, A/P Agings, Deferred Revenue Schedule, and Borrowing Base Certificate |  | Monthly within 30 days after last day of month |  | Yes      |  | No
|Financial Projections                                                      |  | Initial and FYE within 45 days                 |  | Yes      |  | No
|A/R Audit                                                                  |  | Annual                                         |  | Yes      |  | No



|                    |  |           |  |  |  |        |  |            
|------------------- |  | --------- |  |  |  | ------ |  | -----------
|Threshold Event     |  | Minimum   |  |  |  | Actual |  | Trigger    
|Minimum Quick Ratio |  | 2.00:1.00 |  |  |  | :1.00  |  | Yes      No
|                    |  |           |  |  |  |        |  |            



Borrower only has deposit accounts
located at the following institutions: .



Comments Regarding Exceptions: See Attached.



---

|                   
|-------------------
|Sincerely,         
|                   
|XENOGEN CORPORATION
|                   
|SIGNATURE          
|                   
|TITLE              
|                   
|DATE