EXHIBIT 21

SUBSIDIARIES OF ORIENT-EXPRESS HOTELS LTD.

|                                                                                       |                                                          | Jurisdiction
of
Organization                  
|-------------------------------------------------------------------------------------- | -------------------------------------------------------- | ----------------------------------------------
|80 Westcliff (Pty) Ltd.                                                                |                                                          | South Africa                                  
|Alberghiera Fiesolana S.p.A.                                                           |                                                          | Italy                                         
|Byblos S.r.l. Italy
(subsidiary of Alberghiera Fiesolana S.p.A.)                       |                                                          | Italy                                         
|Baie Longue Investissements S.A.                                                       |                                                          | France                                        
|Societé Hoteliere de Baie Longue S.A.
(subsidiary of Baie Longue Investissements S.A.) |                                                          | French W.I.                                   
|Compania Hoteis Palace                                                                 |                                                          | Brazil                                        
|Grampiam Investimentos Hoteleiros S.A.                                                 |                                                          | Portugal                                      
|Hotel Cipriani S.p.A.                                                                  |                                                          | Italy                                         
|Subsidiaries of Hotel Cipriani S.p.A.                                                  |                                                          |                                               
|                                                                                       | Venice Simplon-Orient-Express Ltd.                       |                                               
|                                                                                       | Subsidiaries of Venice Simplon-Orient-Express Ltd.       |                                               
|                                                                                       |                                                          | Northern Belle Ltd.                           
|                                                                                       |                                                          | Venice Simplon-Orient-Express Deutschland GmbH
|                                                                                       |                                                          | Venice Simplon-Orient-Express Voyages S.A.    
|                                                                                       | Venice Simplon-Orient-Express Servizi S.r.l.             |                                               
|Hotelapa Investimento Hoteleiro S.A.                                                   |                                                          | Portugal                                      
|Leisure Holdings Asia Ltd.                                                             |                                                          | Bermuda                                       
|Subsidiaries of Leisure Holdings Asia Ltd.                                             |                                                          |                                               
|                                                                                       | Myanmar Hotels and Cruises Ltd.                          |                                               
|                                                                                       | Vessel Holdings 2 Ltd.                                   |                                               
|Lilianfels Hotel Ltd.                                                                  |                                                          | Bermuda                                       
|Lilianfels Blue Mountains Pty. Ltd.
(subsidiary of Lilianfels Hotel Ltd.)              |                                                          | Australia                                     
|MPP S.A.                                                                               |                                                          | Peru                                          
|Inversiones Malecon de la Reserva S.A.
(subsidiary of MPP S.A.)                        |                                                          | Peru                                          
|Nara Tahiti S.A.                                                                       |                                                          | French Polynesia                              
|Observatory Hotel Ltd.                                                                 |                                                          | Bermuda                                       
|Observatory Hotel Pty. Ltd.
(subsidiary of Observatory Hotel Ltd.)                     |                                                          | Australia                                     
|OEH Peru Ltd.                                                                          |                                                          | Bermuda                                       
|Orient-Express Holdings 1 Ltd.                                                         |                                                          | Bermuda                                       
|Orient-Express Holdings 2 Ltd.                                                         |                                                          | Bermuda                                       
|Orient-Express Holdings 3 Ltd.                                                         |                                                          | Hong Kong                                     
|Orient-Express Holdings 4 Ltd.                                                         |                                                          | Bermuda                                       
|Orient-Express Hotels Inc.                                                             |                                                          | Delaware                                      
|Subsidiaries of Orient-Express Hotels Inc.                                             |                                                          |                                               
|                                                                                       | '21' Club Properties Inc.                                |                                               
|                                                                                       | '21' Club Inc.
(subsidiary of '21' Club Properties Inc.) |                                               
|                                                                                       | Charleston Place Holdings Inc.                           |                                               

|                                                | Mountbay Holdings Inc.                                                     |                                | Delaware
|----------------------------------------------- | -------------------------------------------------------------------------- | ------------------------------ | --------
|                                                | Subsidiaries of Mountbay Holdings Inc.                                     |                                |         
|                                                |                                                                            | Inn at Perry Cabin Corporation |         
|                                                |                                                                            | Keswick Hall Inc.              |         
|                                                | Orient-Express Services Inc.                                               |                                | Delaware
|                                                | Orient-Express Hotels Louisiana Inc.                                       |                                | Delaware
|                                                | Venice Simplon-Orient-Express Inc.                                         |                                | Delaware
|Orient-Express Hotels U.K. Ltd.                 |                                                                            | U.K.                          
|Subsidiaries of Orient-Express Hotels U.K. Ltd. |                                                                            |                               
|                                                | Collection Venice Simplon-Orient-Express Ltd.                              |                                | U.K.    
|                                                | Game Viewers (Pty) Ltd.                                                    |                                | Botswana
|                                                | Gametrackers (Botswana) (Pty) Ltd.
(subsidiary of Game Viewers (Pty) Ltd.) |                                | Botswana
|                                                | Horatio Properties Ltd.                                                    |                                | U.K.    
|                                                | Mount Nelson Hotel Ltd. U.K.
(subsidiary of Horatio Properties Ltd.)       |                                | U.K.    
|                                                | Orient-Express Services Ltd.                                               |                                | U.K.    
|                                                | Reid's Hoteis Lda.                                                         |                                | Portugal
|                                                | Island Hotel (Madeira) Ltd.
(subsidiary of Reid's Hoteis Lda.)             |                                | U.K.    
|                                                | Societa Gestione Esercizi S.p.A.                                           |                                | Italy   
|                                                | Societé de la Cité S.A.                                                    |                                | France  
|Sea Containers Peru Rail Ltd.                   |                                                                            | Bermuda                       
|Windsor Court Hotel Limited Partnership         |                                                                            | Delaware