EXHIBIT 21

SUBSIDIARIES OF ORIENT-EXPRESS HOTELS LTD.

|                                                                                |                                                                            | Jurisdiction
of
Organization                  
|------------------------------------------------------------------------------- | -------------------------------------------------------------------------- | ----------------------------------------------
|                                                                                |                                                                            |                                               
|80 Westcliff (Pty) Ltd.                                                         |                                                                            | South Africa                                  
|Alberghiera Fiesolana S.p.A.                                                    |                                                                            | Italy                                         
|Byblos S.r.l. (subsidiary of Alberghiera Fiesolana S.p.A.)                      |                                                                            | Italy                                         
|Société Hotelière de Baie Longue S.A.                                           |                                                                            | France                                        
|Compania Hoteis Palace                                                          |                                                                            | Brazil                                        
|Grampiam Investimentos Hoteleiros S.A.                                          |                                                                            | Portugal                                      
|Hotel Cipriani S.p.A.                                                           |                                                                            | Italy                                         
|Subsidiaries of Hotel Cipriani S.p.A.                                           |                                                                            |                                               
|                                                                                | Venice Simplon-Orient-Express Ltd.                                         |                                               
|                                                                                | Subsidiaries of Venice Simplon-Orient-Express Ltd.                         |                                               
|                                                                                |                                                                            | Northern Belle Ltd.                           
|                                                                                |                                                                            | Venice Simplon-Orient-Express Deutschland GmbH
|                                                                                |                                                                            | Venice Simplon-Orient-Express Voyages S.A.    
|                                                                                | Venice Simplon-Orient-Express Servizi S.r.l.                               |                                               
|Hotelapa Investimento Hoteleiro S.A.                                            |                                                                            | Portugal                                      
|Hotel Splendido S.r.l.                                                          |                                                                            | Italy                                         
|Subsidiaries of Hotel Splendido S.r.l.                                          |                                                                            |                                               
|                                                                                | Mirna S.r.l.                                                               |                                               
|                                                                                | Collection Venice Simplon-Orient-Express Ltd. (subsidiary of Mirna S.r.l.) |                                               
|                                                                                | Société de la Cité S.A.                                                    |                                               
|La Residencia Ltd.                                                              |                                                                            | U.K.                                          
|Leisure Holdings Asia Ltd.                                                      |                                                                            | Bermuda                                       
|Subsidiaries of Leisure Holdings Asia Ltd.                                      |                                                                            |                                               
|                                                                                | Myanmar Hotels and Cruises Ltd.                                            |                                               
|                                                                                | Vessel Holdings 2 Ltd.                                                     |                                               
|Lilianfels Hotel Ltd.                                                           |                                                                            | Bermuda                                       
|Lilianfels Blue Mountains Pty. Ltd. (subsidiary of Lilianfels Hotel Ltd.)       |                                                                            | Australia                                     
|Miraflores Ventures Ltd.                                                        |                                                                            | B.V.I.                                        
|Plan Costa Maya, S.A. de C.V. (subsidiary of Miraflores Ventures Ltd.)          |                                                                            | Mexico                                        
|MPP S.A.                                                                        |                                                                            | Peru                                          
|Inversiones Malecon de la Reserva S.A. (subsidiary of Miraflores Ventures Ltd.) |                                                                            | Peru                                          
|Nara Tahiti S.A.                                                                |                                                                            | French Polynesia                              
|Observatory Hotel Ltd.                                                          |                                                                            | Bermuda                                       
|Observatory Hotel Pty. Ltd. (subsidiary of Observatory Hotel Ltd.)              |                                                                            | Australia                                     
|OEH Oxford Ltd.                                                                 |                                                                            | Bermuda                                       
|Le Manoir Ltd. (subsidiary of OEH Oxford Ltd.)                                  |                                                                            | U.K.                                          

76

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|                                                               |                                                                               | Jurisdiction
of
Organization  
|-------------------------------------------------------------- | ----------------------------------------------------------------------------- | ------------------------------
|                                                               |                                                                               |                               
|Le Manoir Holdings Ltd. (subsidiary of Le Manoir Ltd.)         |                                                                               | U.K.                          
|Blanc Restaurants Ltd. (subsidiary of Le Manoir Holdings Ltd.) |                                                                               | U.K.                          
|OEH Peru Ltd.                                                  |                                                                               | Bermuda                       
|Orient-Express Holdings 1 Ltd.                                 |                                                                               | Bermuda                       
|Orient-Express Hotels Inc.                                     |                                                                               | Delaware                      
|Subsidiaries of Orient-Express Hotels Inc.                     |                                                                               |                               
|                                                               | '21' Club Properties Inc.                                                     |                               
|                                                               | '21' Club Inc. (subsidiary of '21' Club Properties Inc.)                      |                               
|                                                               | Charleston Place Holdings Inc.                                                |                               
|                                                               | Mountbay Holdings Inc.                                                        |                               
|                                                               | Subsidiaries of Mountbay Holdings Inc.                                        |                               
|                                                               |                                                                               | Inn at Perry Cabin Corporation
|                                                               |                                                                               | Keswick Hall Inc.             
|                                                               | Orient-Express Services Inc.                                                  |                               
|                                                               | Luxury Reservation Services Inc. (subsidiary of Orient-Express Services Inc.) |                               
|                                                               | Orient-Express Hotels Louisiana Inc.                                          |                               
|                                                               | Venice Simplon-Orient-Express Inc.                                            |                               
|                                                               | Orient-Express Travel Inc. (subsidiary of Venice Simplon-Orient-Express Inc.) |                               
|Orient-Express Hotels U.K. Ltd.                                |                                                                               | U.K.                          
|Subsidiaries of Orient-Express Hotels U.K. Ltd.                |                                                                               |                               
|                                                               | Game Viewers (Pty) Ltd.                                                       |                               
|                                                               | Gametrackers (Botswana) (Pty) Ltd. (subsidiary of Game Viewers (Pty) Ltd.)    |                               
|                                                               | Horatio Properties Ltd.                                                       |                               
|                                                               | Mount Nelson Hotel Ltd. (subsidiary of Horatio Properties Ltd.)               |                               
|                                                               | Orient-Express Services Ltd.                                                  |                               
|Reid's Hoteis Lda.                                             |                                                                               | Portugal                      
|Island Hotel (Madeira) Ltd. (subsidiary of Reid's Hoteis Lda.) |                                                                               | U.K.                          
|Sea Containers Peru Rail Ltd.                                  |                                                                               | Bermuda                       
|Windsor Court Hotel Limited Partnership                        |                                                                               | Delaware                      

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