EXHIBIT 10.2



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|AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT |  | 1. CONTRACT ID CODE |  | PAGE OF PAGES 1                2



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|2. AMENDMENT/MODIFICATION NO.                                                                                                         |  | 3. EFFECTIVE DATE                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |  | 4. REQUISITION/PURCHASE REQ. NO.  |  | 5. PROJECT NO.     (if applicable)
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|03                                                                                                                                    |  | 09/24/2005                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |  | NA                                |  |                                   
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|6. ISSUED
BY                                     CODE                                                                                 |  | 7. ADMINISTERED BY (If other than Item 6)
                    CODE                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         
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|National Institute of Environmental Health Sciences Acquisitions Management Branch/OM P.O. Box 12874 Research Triangle Park, NC 27709 |  | OMB No. 0990-0115 Deltra C. Lunney 919-541-0387                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
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|8. NAME AND ADDRESS OF CONTRACTOR (No. street, city, State and ZIP Code)                                                              |  | x                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |  | 9A. AMENDMENT OF SOLICITATION NO.
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|                                                                                                                                      |  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |  |                                   |  |                                    |  |   |  | 9B. DATED (SEE ITEM 11)                
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|Xenogen Biosciences 5 Cedar Brook Drive Cranbury, NJ 08512 Attn: Stephen McAndrew                                                     |  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |  |                                   |  |                                    |  |   |  | 10A. MODIFICATION OF CONTRACT/ORDER
NO.
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|                                                                                                                                      |  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |  |                                   |  |                                    |  | x |  | 273-03-C-0045                          
|                                                                                                                                      |  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             |  |                                   | 
|                                                                                                                                      |  | CR300045                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    |  | B2                                |  |                                    |  |   |  | 10B. DATED (SEE ITEM 13) 9/25/2003     
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|CODE                                                                                                                                  |  | FACILITY CODE                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               |  |                                   |  |                                   
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|11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS                                                                            
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| ̈                                                                                                                                     |  | The above numbered solicitation is amended as set forth in Item 14. The hour and data specified for receipt of Offers.                                                                                                                                                                                                                                                                                                                                                                                                                                                      |  |  ̈is extended ̈is not extended     
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|                                                                                                                                      |  | Offers must acknowledge receipt of the amendment prior to the hour and date specified in the specification or as amended, by one of the following methods:                                                                                                                                                                                                                                                                                                                                                                                                                 
|                                                                                                                                      | 
|                                                                                                                                      |  | (a) By completing items 8 and 15, and returning  copies of the amendment (b) by acknowledging receipt
of this amendment on each copy of the offer submitted; or                                                                                                                                                                                                                                                                                                                                                                                                            
|                                                                                                                                      | 
|                                                                                                                                      |  | (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGEMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR
THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram
or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.
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|12. ACCOUNTING AND APPROPRIATION DATA (If required)                                                                                  
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|EIN:    1311122130A2                                                                                                                 
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|13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS. IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.         



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|x |  | A.     THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN
ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.                                                                     
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|  |  | B.     THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as
changes in paying office, appropriation date, etc.) SET FORTH IN ITEM 14. PURSUANT TO THE AUTHORITY OF FAR 43,103(B).
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|  |  | C.     THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:                                                                                                                                             
|  | 
|  |  | D.     OTHER (Specify type of modification and authority )                                                                                                                                                               
|  | 
|x |  | FAR 43,103(a) Bilateral Modification                                                                                                                                                                                     



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|E. IMPORTANT: Contractor ̈is not,    x is required to sign this document and return    2 copies to the issuing office.                                                      
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|14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.) Purpose of this
modification:



1) To
extend the base performance period

2) To summarize the impact on award and obligation amounts



Except as provided herein, all terms and conditions of the document referenced in Item 9A or
10A, as therefore changed, remains unchanged and in full force and effect.

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|--------------------------------------------------------------- |  | ---------------------------------------------------------- |  | ------------------------------------------------------------------- |  | ----------------
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|15A. NAME AND TITLE OF SIGNER (Type or print)                   |  | 16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)
|                                                                |  |                                                            | 
|Stephen J. McAndrew, Ph.D. Vice President, Business Development |  |                                                            |  | Antoinette Bridges, Contracting Officer                             |  |                 
|                                                                |  |                                                            | 
|15B. CONTRACTOR/OFFEROR                                         |  | 15C. DATE SIGNED                                           |  | 16B. UNITED STATES OF AMERICA                                       |  | 16C. DATE SIGNED
|                                                                |  |                                                            | 
|/S/ STEPHEN J. MCANDREW                                         |  | 9/27/05                                                    |  | /S/ ANTOINETTE BRIDGES                                              |  | 10/7/05         
|                                                                |  |                                                            | 
|(Signature of person authorized to sign)                        |  |                                                            |  | (Signature of Contracting Officer)                                  |  |                 
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|NSN 7540 - 01 - 152 - 8070 PREVIOUS EDITION
UNUSABLE            |  |                                                            |  | STANDARD FORM 30 (REV. 10-83) Prescribed by GSA FAR [40 CFR]
50,243



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|AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT |  | 1. CONTRACT ID CODE |  | PAGE OF PAGES 2                2



Contract #:
273-03-C-0045                     Xenogen Biosciences

Modification #: 03



1) The base performance
period is extended from September 24, 2005 to October 31, 2006 to allow for completion and delivery of existing projects.



2) Summary for Clarification Purposes:



(a) The completion date of September 24, 2005 is changed to October 30, 2006 by reason of this modification.



(b) The contract award and obligation amount [***] is unchanged by reason of
this modification.



|                                  |  |         |  |          
|--------------------------------- |  | ------- |  | ---------
|                                  |  | Awarded |  | Obligated
|Prior to this Modification # 03:  |  | [***]   |  | [***]    
|Changed per this Modification 03: |  | 0.00    |  | 0.00     
|                                  |  |         |  |          
|Current/New Totals:               |  | [***]   |  | [***]    
|                                  |  |        
|Completion Date: October 30, 2006 |  |         |  |          

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|*** | CONFIDENTIAL TREATMENT REQUESTED FOR PORTIONS OF THIS EXHIBIT
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|NSN 7540 - 01 - 152 - 8070 PREVIOUS EDITION
UNUSABLE |  | CONTINUATION PAGE |  | STANDARD FORM 30(REV. 10-83) Prescribed by
GSA FAR(40 CFR) 53343