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EXHIBIT 31.1 

I, Michael Lee, chief executive officer of AlphaRx, Inc.certify that: 

1.    I havereviewed this quarterly report on Form 10-QSB of AlphaRx, Inc.; 
2.    Based on my knowledge, this report doesnot contain any untrue statement of a material fact or omit to state a materialfact necessary to make the statements made, in light of the circumstances underwhich such statements were made, not misleading with respect to the periodcovered by this report; 

3.    Based on my knowledge, the financialstatements, and other financial information included in this report, fairlypresent in all material respects the financial condition, results of operationsand cash flows of the small business issuer as of, and for, the periodspresented in this report; 

4.    The small business issuer’s othercertifying officer(s) and I are responsible for establishing and maintainingdisclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e)and 15d-15(e)) and internal control over financial reporting (as defined in theExchange Act Rules 13a-15(f) and 15d-15(f)) for the small business issuer andhave: 

a)  designed such disclosure controlsand procedures, or caused such disclosure controls and procedures to be designedunder our supervision, to ensure that material information relating to the smallbusiness issuer, including its consolidated subsidiaries, is made known to us byothers within those entities, particularly during the period in which thisreport is being prepared;

b)   designed such internal control over financial reporting, or caused such internalcontrol over financial reporting to be designed under our supervision, toprovide reasonable assurance regarding the reliability over financial reportingand the preparation of financial statements for external purposes in accordancewith generally accepted accounting principles; 

c)    evaluated the effectiveness of the small business issuer’s disclosure controlsand procedures and presented in this report our conclusions about theeffectiveness of the disclosure controls and procedures, as of the end of theperiod covered by this report based on such evaluation; and 

d)    disclosed in this report any change in the small business issuer’s internalcontrol over financial reporting that occurred during the small businessissuer’s most recent fiscal quarter(the small business issuer’s fourth fiscalquarter in the case of an annual report) that has materially affected, or isreasonably likely to materially affect, the small business issuer’s internalcontrol over financial reporting; and 

5.    The small business issuer’s othercertifying officer(s) and I have disclosed, based on our most recent evaluationof internal control over financial reporting, to the small business issuer’sauditors and the audit committee of the small business issuer’s board ofdirectors (or persons performing the equivalent functions): 

a)    all significant deficiencies and material weaknesses in the design or operationof internal control over financial reporting which are reasonably likely toadversely affect the small business issuer’s ability to record, process,summarize and report financial information; and 

b)   any fraud, whether or not material, that involves management or other employeeswho have a significant role in the small business issuer's internal control overfinancial reporting. 
Date: May 15, 2007/s/    Michael Lee   Michael    Lee, President and Chief Executive Officer