**Exhibit 1.1**

** **
|                                                                                                                                                                                                                              | Industry Canada | Industrie  Canada                                                                                                                                                                                                                                                                                   |
|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|-----------------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|                                                                                                                                                                                                                         |            |                                                                                                                                                                                                                                                                                                |
| **Restated Certificate**                                                                                                                                                                                                     | ** **      | **Certificat**                                                                                                                                                                                                                                                                                      |
| **of Incorporation**                                                                                                                                                                                                         | ** **      | **de constitution à jour**                                                                                                                                                                                                                                                                     |
|                                                                                                                                                                                                                         |            |                                                                                                                                                                                                                                                                                                |
| **Canada Business**                                                                                                                                                                                                          | ** **      | **Loi canadienne sur**                                                                                                                                                                                                                                                                              |
| **Corporations Act**                                                                                                                                                                                                         | ** **      | **les sociétés par actions**                                                                                                                                                                                                                                                              |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          |
| **AETERNA ZENTARIS INC.**                                                                                                                                                                                                    | ** **      | **264271-9**                                                                                                                                                                                                                                                                                        |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          | ** ** | ** ** |
| Name of  corporation-Dénomination de la société                                                                                                                                                               | ** **      | Corporation number-Numéro de la société                                                                                                                                                                                                                                              | ** ** |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          |
| I hereby certify that the articles of incorporation of the  above-named corporation were restated under section 180 of the *Canada  Business Corporations Act*as set out in the attached restated articles of incorporation. | ** **      | Je certifie que les statuts constitutifs de la société susmentionnée ont été mis à jour en vertu de l’article 180 de la *Loi canadienne sur les  soci*é*t*é*s par actions,*tel qu’il est indiqué dans les statuts mis à jour ci-joints. |
| ** **                                                                                                                                                                                                                   | ** **      | ** **                                                                                                                                                                                                                                                                                          |
|                                                                                                                                                                                                                              | ** **      | **June 1, 2004 / le 1 juin  2004**                                                                                                                                                                                                                                                             |
|                                                                                                                                                                                                                         | ** **      |                                                                                                                                                                                                                                                                                                |
| Director - Directeur                                                                                                                                                                                                         | ** **      | Effective Date of Restatement -  Date d’entrée en vigueur de la mise à jour                                                                                                                                                                                                          |
|                                                                                                                                                                                                                              | ** **      |                                                                                                                                                                                                                                                                                                |
|                                                                                                                                                                                                                              |                 |                                                                                                                                                                                                                                                                                                     |  |  |  |  |

 

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|                                                                                                                                                                                                                           | Industry  Canada                                                                                                       |                                                                                                                                                                                                                                 | Industrie  Canada                                                  |                   | **FORM 7**          |              | **FORMULAIRE 7**         |
|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|------------------------------------------------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------------------------------------------------------------------|------------------------|--------------------------|-------------------|--------------------------|
|                                                                                                                                                                                                                      | Canada  Business                                                                                                       |                                                                                                                                                                                                                                 | Loi  canadienne sur les                                            |                   | **RESTATED ARTICLES OF** |              | **STATUTS CONSTITUTIFS** |
|                                                                                                                                                                                                                      | Corporations  Act                                                                                                      |                                                                                                                                                                                                                                 | sociétés par actions                                     |                   | **INCORPORATION**        |              | **MIS À JOUR**      |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               | **(SECTION 180)** |                     | **(ARTICLE 180)** |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 1 -    Name of the Corporation - Dénomination sociale de la société                                                                                                                         |                                                                                                                   |                                                                                                                                                                                                                                 | Corporation  No. - N° de la société            |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| AETERNA ZENTARIS INC.                                                                                                                                                                                                     |                                                                                                                   |                                                                                                                                                                                                                                 | 264271-9                                                           |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 2 -    The province or territory in Canada where the registered office is  situated                                                                                                                        | La province  ou le territoire au Canada où est situé le siège social                                    |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| JUDICIAL DISTRICT OF QUÉBEC, PROVINCE OF QUÉBEC                                                                                                                                                                 |                                                                                                                   |                                                                                                                                                                                                                                 |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 3 -    The classes and any maximum number of shares that the   corporation is authorized to issue                                                                                                          | Catégories  et tout nombre maximal d’actions que la société est autorisée á émettre |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| ·                  an unlimited number of common shares;                                                                        |                                                                                                                   |                                                                                                                                                                                                                                 |
| ·                  an unlimited number of First Preferred Shares, issuable in series;  and                                      |                                                                                                                   |                                                                                                                                                                                                                                 |
| ·                  an unlimited number of Second Preferred Shares, issuable in  series;                                         |                                                                                                                   |                                                                                                                                                                                                                                 |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| and the rights, privileges, restrictions  and conditions attaching these shares are set out in the annexed Schedule 1  which is incorporated in this form.                                                                |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 4 -    Restrictions, if any, on share transfers                                                                                                                                                            |                                                                                                                   |                                                                                                                                                                                                                                 | Restrictions  sur le transfert des actions, s’il y a lieu     |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| NOT APPLICABLE                                                                                                                                                                                                            |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 5 -    Number (or minimum and maximum number) of directors                                                                                                                                                 |                                                                                                                   |                                                                                                                                                                                                                                 | Nombre (ou  nombre minimal et maximal) d’administrateurs      |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| MINIMUM 5 – MAXIMUM 15                                                                                                                                                                                               |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 6 -    Restrictions, if any, on business the corporation may carry on                                                                                                                                      |                                                                                                                   | Limites  imposées à l’activité  commerciale de la société, s’il y a lieu                                                                                                                          |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| NOT APPLICABLE                                                                                                                                                                                                            |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| 7 -    Other provisions, if any                                                                                                                                                                            |                                                                                                                   |                                                                                                                                                                                                                                 | Autres  dispositions, s’il y a lieu                           |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |              |
| NOT APPLICABLE                                                                                                                                                                                                            |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |
|                                                                                                                                                                                                                      |                                                                                                                   |                                                                                                                                                                                                                                 |                                                               |                   |                     |
| These  restated articles of incorporation correctly set out, without substantive  change, the corresponding provisions of the articles of incorporation as  amended and supersede the original articles of incorporation. |                                                                                                                   | Cette mise à jour des statuts constitutifs démontre  exactement, sans changement substantiel, les dispositions correspondantes des  statuts constitutifs modifiés qui remplacent les statuts constitutifs  originaux. |
|                                                                                                                                                                                                                      |
| Signature

/s/ Mario  Paradis                                                                                                                                                                                             | Printed Name  – Nom en lettres moulées  Mario Paradis                                                        | 8 – Capacity  of – En qualité de  Corporate Secretary                                                                                                                                                                 | 9 – Tel.  No. – N° de tél.  (418)652-8525 |
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| **FOR  DEPARTMENTAL USE ONLY – Á L’USAGE DU MINISTÈRE SEULEMENT**                                                                                                                                     |                                                                                                                   |
|                                                                                                                                                                                                                      |                                                                                                                   |
| **JUN  1 – 2004**                                                                                                                                                                                                    |                                                                                                                   |
| ** **                                                                                                                                                                                                                |                                                                                                                   |
| IC3167  (2003/08)                                                                                                                                                                                                         |                                                                                                                        |
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**SCHEDULE 1**

** **

**TO THE RESTATED ARTICLES OF**

** **

**Æ****TERNA ZENTARISINC.**

 

The authorized share capital of ÆternaZentaris Inc. (the **“Corporation”**) shall consist of an unlimited numberof Common Shares, an unlimited number of First Preferred Shares, issuable inseries, and an unlimited number of Second Preferred Shares, issuable in series.For the purposes of this Schedule 1 to the Restated Articles of the Corporation,any reference to Subordinate Voting Shares shall be deemed to be to the CommonShares. The rights, privileges, restrictions and conditions attaching to eachclass of shares are as follows:

 

**ARTICLE 1COMMON SHARES**

 

1.1                                Voting Rights. The holders of the CommonShares shall be entitled to one (1) vote for each Common Share held by them atall meetings of shareholders, except meetings at which only shareholders of aspecified class of shares are entitled to vote.

 

1.2                                Dividend Rights. Subject to section 2.3hereof, the holders of the Common Shares shall be entitled to receive suchdividends as are declared by the Board of Directors of the Corporation on theCommon Shares.

 

1.3                                Liquidation Rights. The holders of theCommon Shares shall be entitled to receive, subject to the other provisionshereof, the remaining property of the Corporation upon any liquidation,dissolution or winding-up of the affairs of the Corporation, whether voluntaryor involuntary.

 

**ARTICLE 2FIRST PREFERRED SHARES AND SECOND PREFERRED SHARES**

 

The First Preferred Shares and the SecondPreferred Shares (such shares being hereinafter sometimes collectively referredto as the “Preferred Shares”) shall be issuable in series and the rights,privileges, restrictions and conditions attaching thereto are as follows:

 

2.1                                 Issuance in Series

 

The Preferred Shares shall be issuable at anytime in one or more series, as provided above, which shares shall rank equally,within their respective series, in regard to the payment of dividends and the distributionof property in the event of the liquidation, dissolution or winding-up of theCorporation or the distribution of all or part of its assets among theshareholders.

 

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The Board of Directors may, from time totime, provide for series of Preferred Shares to be created and issued. Beforeany Preferred Shares of a given series are issued, the Board of Directorsshall:

 

2.1.1                      determine how such series of First Preferred Shares or SecondPreferred Shares is to be designated;

 

2.1.2                      determine the number of First Preferred Shares or Second Preferred Sharesthat will make up such series;

 

2.1.3                      determine,subject to the attributes common to all the Preferred Shares, the rights,privileges, restrictions and conditions attaching to such series of shares, including,but without limiting the generality of the foregoing:

 

2.1.3.1            the rate, amount or method of calculation of the dividend applicableto the shares of such series, the method of payment of such dividend andwhether it is cumulative or non-cumulative; and

 

2.1.3.2            such rights, privileges, restrictions and conditions, if any, as maybe considered appropriate in regard to the acquisition of such shares by theCorporation (at the option of the Corporation, at the option of the holder orotherwise), the creation of a sinking fund or purchase fund with respectthereto, the transfer of such shares or the exchange or conversion thereof intoshares of another series or class; and

 

2.1.4        amend the articles of the Corporation accordingly, in conformitywith the *Canada Business Corporations Act*.

 

2.2           Voting

 

The holders of the Preferred Shares shall notbe entitled to receive notice of or to attend or vote at meetings ofshareholders.

 

2.3                                Dividends

 

2.3.1                      The holders of Preferred Shares of a series shall be entitled toreceive, with respect to each financial year of the Corporation or such otherperiod as may be specified in the articles of amendment with respect to suchseries, preferential dividends, the rate, amount or method of calculation andthe method of payment of which dividend, and whether it is cumulative ornon-cumulative, shall be as determined in the relevant articles of amendment. 

 

2.3.2                      The holders of Preferred Shares of a series shall not, as such, beentitled to any further dividend or any dividend other than the specific 

 

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preferentialdividend provided for in the articles of amendment with respect to such series.

 

2.3.3                      No dividend may be declared, paid or set aside for payment, during afinancial year of the Corporation or such other period specified in therelevant articles of amendment, on the Second Preferred Shares, the SubordinateVoting Shares and the Multiple Voting Shares or any other share of the sharecapital of the Corporation ranking junior to the First Preferred Shares, unlessany current dividend on any First Preferred Shares then outstanding and anyaccrued dividends on any such shares with a cumulative dividend shall firsthave been declared and paid or set aside for payment with respect to the sameyear or period.

 

2.3.4                      No dividend may be declared, paid or set aside for payment, during afinancial year of the Corporation or such other period specified in therelevant articles of amendment, on the Subordinate Voting Shares and theMultiple Voting Shares or any other share of the share capital of theCorporation ranking junior to the Second Preferred Shares, unless any currentdividend on any Second Preferred Shares then outstanding and any accrueddividends on any such shares with a cumulative dividend shall first have been declaredand paid or set aside for payment with respect to the same year or period

 

2.3.5                      The dividend applicable to any Preferred Share of a series with a cumulativedividend shall begin to accrue from the date such shares are issued, unless thearticles of amendment with respect to such series provide for a different date,in which case such cumulative dividend shall begin to accrue from the datespecified in the relevant articles of amendment.

 

2.3.6                      The dividend applicable to any Preferred Share of a series with a cumulativedividend shall be earned only at the end of a financial year or of such otherperiod to which it relates, unless the articles of amendment with respect tosuch series provide that such dividend is to be earned on a daily basis or inany other manner, in which case the relevant articles of amendment shallprevail.

 

2.3.7                      Where an amount declared as a dividend is insufficient to pay any currentdividend on any Preferred Shares then outstanding and any accrued dividends onany such shares with a cumulative dividend, the holders of Preferred Sharesshall participate in such dividend on an equal basis within their respectiveseries, in proportion to the amounts that would be payable if current andaccrued dividends were paid in full.

 

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2.4                                 Liquidation, Dissolution or Winding-Up

 

2.4.1                      In the event of the liquidation of the Corporation, the distributionof its property upon its dissolution or winding-up, or the distribution of allor part of its assets among the shareholders, the holders of Preferred Sharesof every series shall receive, in cash or in kind, an amount equal to the valueof the consideration paid in respect of such shares outstanding, as credited tothe issued and paid-up share capital account of the Corporation, together with:

 

2.4.1.1             in the case of Preferred Shares with a cumulative dividend, theamount of any dividends then accrued or declared on such shares and unpaid;

 

2.4.1.2             in the case of Preferred Shares with a non-cumulative dividend, theamount of any dividends then declared on such shares and unpaid; and

 

2.4.1.3             all other amounts, if any, specified in the articles of amendmentcreating the share series concerned.

 

2.4.2                      The holders of First Preferred Shares shall be entitled to receivethese amounts in preference and priority to any participation of holders ofSecond Preferred Shares, Subordinate Voting Shares and Multiple Voting Sharesor shares of any other class of shares of the share capital of the Corporationranking junior to the First Preferred Shares, on an equal basis, in proportionto the amount of their respective claims in regard to such shares held by them.

 

2.4.3                      The holders of Second Preferred Shares shall be entitled to receivethese amounts in preference and priority to any participation of holders of SubordinateVoting Shares and Multiple Voting Shares or shares of any other class of sharesof the share capital of the Corporation ranking junior to the Second PreferredShares, on an equal basis, in proportion to the amount of their respectiveclaims in regard to such shares held by them.

 

2.4.4                      The holders of Preferred Shares shall not be entitled to participatefurther in such distribution, the remaining property of the Corporationdevolving to holders of the other shares of the share capital of the Corporationaccording to their respective rights.

 

2.5                                 Amendments

 

2.5.1                      Subject to the provisions of sections 173 and following of the *Canada Business Corporations Act*and subject to the articlesof the Corporation being amended, the Board of Directors may at any time adopta resolution to modify, amend, suspend or repeal the rights, privileges,restrictions and conditions attaching to any Preferred Shares in order toauthorize the creation of shares of a new class ranking prior to or having

 

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thesame rank as such Preferred Shares in regard to dividends or distribution ofproperty in the event of the liquidation, dissolution or winding-up of theCorporation or the distribution of all or part of its assets among theshareholders, or in order to make the shares of an existing class rank prior toor have the same rank as such Preferred Shares in regard thereto, but no suchresolution shall be effective unless ratified by at least three quarters (3/4) of the votes castby the holders of Preferred Shares of each series affected by such amendment,voting separately as a series, present or represented at a meeting called andheld for such purpose; a meeting may nevertheless be held jointly with othershareholders provided that a separate vote is taken among holders of PreferredShares of each series affected by such amendment. The formalities to beobserved in regard to the calling and conduct of any such meeting and thequorum therefor shall be those prescribed in the by-laws of the Corporation inregard to meetings of holders of shares carrying the right to vote atshareholders’ meetings, *mutatis mutandis*.A vote with respect to Preferred Shares may also be expressed by resolution inwriting signed by all the holders entitled to vote on the resolution concerned.

 

2.5.2                      If the proposed amendment stands to affect the rights of holders of PreferredShares of a given series in a manner or to an extent significantly differentfrom the manner or extent to which it affects the rights of holders ofPreferred Shares of any other series, such amendment must then, in addition tobeing approved by the holders of Preferred Shares of each series affected bythe amendment, voting as a series as provided above, be approved, in the samemanner, by the holders of Preferred Shares of every such series, votingseparately as a series, and the provisions of article 2.5.1 shall apply to theprocedure for obtaining such approval, *mutatis mutandis.*

 

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