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                                                                 Exhibit 10.21


                              EMPLOYMENT AGREEMENT

         This Agreement, dated November 19, 1999, by and between LAKARO
BIOPHARMACEUTICALS, INC. ("Lakaro"), a Delaware corporation having an address at
216 Jaffa Rd., Sha'arei Ha'ir, Jerusalem, Israel 94383 and IRA WEINSTEIN, an
individual residing at 5/3 Mishol Uzrad, Jerusalem, Israel (the "Treasurer")

WITNESSETH:

         WHEREAS, the Corporation desires to employ the Treasurer as Treasurer
of Lakaro and the Treasurer desires to be employed by the Lakaro as Treasurer of
Lakaro, all pursuant to the terms and conditions hereinafter set forth;

         NOW THEREFORE, in consideration of the foregoing and the mutual
promises and covenants herein contained, it is agreed as follows:


1.       EMPLOYMENT DUTIES

         (a) Lakaro hereby engages and employs the Treasurer, and the Treasurer
accepts engagement and employment, as Treasurer of Lakaro, to direct, supervise
and have responsibilities for the financial affairs of Lakaro and for any other
appropriate areas and tasks which the Board of Directors and/or the Chief
Executive Officer may assign to him. The Treasurer acknowledges and agrees that
the performance by the Treasurer of his duties hereunder may require significant
domestic and international travel by the Treasurer. In addition, the Treasurer
realizes that he may be required to spend a substantial amount of time in
Jerusalem, Israel.

         (b) The Treasurer shall devote substantially all of his gainful time to
the discharge of his duties and responsibilities under this Agreement.


2.       TERM

         The Treasurer's employment hereunder shall be for a term of three (3)
years commencing on the Effective Date and continuing through the third
anniversary of the Effective Date (the "Initial Term"), with successive one-year
renewals thereafter (the "Renewal Terms") unless sooner terminated as
hereinafter provided, or by notice of either party not less than 90 days prior
to the expiration of each term.

3.       COMPENSATION

         (a) As compensation for the performance of his duties on behalf of
Lakaro, the Treasurer shall be compensated as follows:

                  (i) Upon the next meeting of the Corporation's Board of
Directors, the Corporation will grant (the "Initial Grant") the Treasurer
options (the "Options") to purchase 150,000 shares of the common stock of the
Corporation at an exercise price equal to $0.15 per share (the "Exercise
Price"), which options shall be exercisable for a period of 10 years from the
date of issuance. Should any change be made to the Common Stock by reason of any
stock split, stock dividend, recapitalization, combination of shares, exchange
of shares or other change affecting the outstanding Common Stock as a class
without the Corporation's receipt of consideration, appropriate adjustments
shall be made to (i) the total number and/or class of securities subject to such
options and (ii) the Exercise Price in order to reflect such change and thereby
preclude a dilution or enlargement under such options.

                  (ii) The stock options shall vest as follows: one-third on the
closing of the next equity investment in Lakaro; one-sixth six months from the
date of grant; one-sixth twelve months from the date of grant; one-sixth
eighteen months from the date of grant; and one-sixth twenty four months

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from the date of grant; but immediate vesting shall occur upon a change of
control of the Corporation as described in paragraph 10(a)(iii)C below.

                  (iii) At the discretion of the Board of Directors, the
Treasurer shall be entitled to an annual grant of subsequent stock options each
of which shall have the same antidilution protection as described in Section 3
paragraph (a)(i) above.

         (b) Lakaro shall reimburse the Treasurer for all normal, usual and
necessary expenses incurred by the Treasurer in furtherance of the business and
affairs of Lakaro, including travel and entertainment, against receipt by Lakaro
of appropriate vouchers or other proof of the Treasurer's expenditures and
otherwise in accordance with such Expense Reimbursement Policy as may from time
to time be adopted by the Board of Directors of Lakaro.

         (c) The Treasurer shall be, during the term of this Agreement, entitled
to four (4) weeks of vacation per year as well as all statutory holidays.

         (d) Lakaro shall adopt as part of the Corporation's Bylaws a broad form
indemnity of all actions taken in good faith by the officers and directors of
the Corporation.

         (e) Subject to Section 10(c) below, the Treasurer must be an employee
of Lakaro at the time any compensation is due in order to receive such
compensation. In addition, no options shall vest after the termination of this
Agreement.


4.       REPRESENTATIONS AND WARRANTIES
         BY THE TREASURER AND LAKARO

         (a) The Treasurer hereby represents and warrants to Lakaro as follows:

                  (i) Neither the execution and delivery of this Agreement nor
the performance by the Treasurer of his duties and other obligations hereunder
violate any statute, law, determination or award, or conflict with or constitute
a default under (whether immediately, upon the giving of notice or lapse of time
or both) any prior employment agreement, contract, or other instrument to which
the Treasurer is a party or by which he is bound.

                  (ii) The Treasurer has the full right, power and legal
capacity to enter and deliver this Agreement and to perform his duties and other
obligations hereunder. This Agreement constitutes the legal, valid and binding
obligation of the Treasurer enforceable against him in accordance with its
terms. No approvals or consents of any persons or entities are required for the
Treasurer to execute and deliver this Agreement or perform his duties and other
obligations hereunder.

         (b) Lakaro hereby represents and warrants to the Treasurer as follows:

                  (i) Lakaro is duly organized, validly existing and in good
standing under the laws of the State of Delaware, with all requisite corporate
power and authority to own its properties and conduct its business in the manner
presently described.

                  (ii) Lakaro has the full power and authority to enter into
this Agreement and to incur and perform its obligations hereunder.

                  (iii) The execution, delivery and performance by Lakaro of
this Agreement does not conflict with or result in a breach or violation of or
constitute a default under (whether immediately, or upon the giving of notice or
lapse of time or both) the certificate of incorporation or by-laws of Lakaro, or
any agreement or instrument to which Lakaro is a party or by which Lakaro or any
of its properties may be bound or affected.

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5.       CONFIDENTIAL INFORMATION

         (a) The Treasurer agrees that during the course of his employment and
at any time thereafter, he will not disclose or make accessible to any other
person, Lakaro's products, services and technology, both current and under
development, promotion and marketing programs, lists, trade secrets and other
confidential and proprietary business information of Lakaro or any of its
clients. The Treasurer agrees: (i) not to use any such information for himself
or others; and (ii) not to take any such material or reproductions thereof from
Lakaro's facilities at any time during his employment by Lakaro, except as
required in the Treasurer's duties to Lakaro. The Treasurer agrees immediately
to return all such material and reproductions in his possession to Lakaro upon
request and in any event upon termination of employment. Nothing in the
foregoing shall be construed to prevent the Treasurer from disclosing or using
any information which the Treasurer can show by written documentation was in the
public domain or enters into the public domain through no improper act on the
Treasurer's part or on the part of any of Lakaro's employees or was in his
possession prior to his joining Lakaro or disclosed properly to the Treasurer
after leaving Lakaro.

         (b) Except with prior written authorization by Lakaro, the Treasurer
agrees not to disclose or publish any of the confidential, technical or business
information or material of Lakaro, its clients or any other party to whom Lakaro
owes an obligation of confidence, at any time during or for a period of two
years after his employment with Lakaro except in the event of involuntary no
cause termination by Lakaro or a termination by the Treasurer for cause.

6.       NON-COMPETITION

         (a) The Treasurer understands and recognizes that his services to
Lakaro are special and unique and agrees that, during the term of this
Agreement, and for a period of 12 months from the date of termination of his
employment hereunder, he shall not in any manner, directly or indirectly, on
behalf of himself or any person, firm, partnership, joint venture, corporation
or other business entity ("Person"), enter into or engage in any business
directly competitive with Lakaro's business, either as an individual for his own
account, or as a partner, joint venturer, Treasurer, agent, consultant,
salesperson, officer, director or shareholder of a Person operating or intending
to operate within the area that Lakaro is, at the date of termination,
conducting its business (the "Restricted Businesses"); provided, however, that
nothing herein will preclude the Treasurer from holding one percent (1%) or less
of the stock of any publicly traded company or from holding a position with a
Person who does not engage in a business directly competitive with the
Restrictive Businesses so long as the Treasurer works in a division of such
Person which carries on a bona fide business which is not directly competitive
with the Restricted Businesses.

         (b) For a period of 12 months after the termination of this Agreement,
the Treasurer shall not interfere with or disrupt or attempt to disrupt Lakaro's
business relationship with any of its customers, or solicit any of the employees
of Lakaro.

         (c) In the event that the Treasurer breaches any provisions of this
Section 6 or there is a threatened breach, then, in addition to any other rights
which Lakaro may have, Lakaro shall be entitled, without the posting of a bond
or other security, to injunctive relief to enforce the restrictions contained
herein. In the event that an actual proceeding is brought in equity to enforce
the provisions of this Section 6, the Treasurer shall not argue as a defense
that there is an adequate remedy at law nor shall Lakaro be prevented from
seeking any other remedies which may be available.

7.       OWNERSHIP OF PROPRIETARY INFORMATION

                  (a) The Treasurer agrees that all information that has been
created, discovered or developed by Lakaro, its subsidiaries, affiliates,
successors or assigns (collectively, the "Affiliates") (including, without
limitation, information relating to the development of Lakaro's business
created, discovered, developed or made know to Lakaro or the Affiliates by
Treasurer during the Term and information relating to Lakaro's customers,
suppliers, consultants, and licensees) and/or in which property rights have been
assigned or otherwise conveyed to Lakaro or the Affiliates, shall be the sole
property of Lakaro or the Affiliates, as applicable, and Lakaro or the
Affiliates, as the case may be, shall be the sole owner of all patents,
copyrights and other rights in connection therewith, including but

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not limited to the right to make application for statutory protection. All of
the aforementioned information is hereinafter called "Proprietary Information."
By way of illustration, but not limitation, Proprietary Information includes
trade secrets, processes, discoveries, structures, inventions, designs, ideas,
works of authorship, copyrightable works, trademarks, copyrights, formulas,
data, know-how, show-how, improvements, inventions, product concepts,
techniques, information or statistics contained in, or relating to, marketing
plans, strategies, forecasts, blueprints, sketches, records, notes, devices,
drawings, customer lists, patent applications, continuation applications,
continuation-in-part applications, file wrapper continuation applications and
divisional applications and information about Lakaro's or the Affiliates'
employees and/or consultants (including, without limitation, the compensation,
job responsibility and job performance of such employees and/or consultants).

                  (b) The Treasurer further agrees that at all times, both
during the Term and after the termination of this Agreement, he will keep in
confidence and trust all Proprietary Information, and he will not use or
disclose any Proprietary Information or anything directly relating to it without
the written consent of Lakaro or the Affiliates, as appropriate, except as may
be necessary in the ordinary course of performing his duties hereunder and
except for academic, non-commercial research purposes with the prior written
approval of the Board of Directors. The Treasurer acknowledges that the
Proprietary Information constitutes a unique and valuable asset of Lakaro and
each Affiliate acquired at great time and expense, which is secret and
confidential and which will be communicated to Treasurer, if at all, in
confidence in the course of his performance of his duties hereunder, and that
any disclosure or other use of the Proprietary Information other than for the
sole benefit of Lakaro or the Affiliates would be wrongful and could cause
irreparable harm to Lakaro or the Affiliates, as the case may be.

                  Notwithstanding the foregoing, the parties agree that, at all
such times, Treasurer is free to use (i) information in the public domain not as
a result of a breach of this Agreement, (ii) information lawfully received from
a third party and (iii) Treasurer's own skill, knowledge, know-how and
experience to whatever extent and in whatever way he wishes, in each case
consistent with his obligations as Treasurer and that, at all times, Treasurer
is free to conduct any non-commercial research not relating to Lakaro's
business.


8.       DISCLOSURE AND OWNERSHIP OF INVENTIONS

         (a) During the Term, the Treasurer agrees that he will promptly
disclose to Lakaro, or any persons designated by Lakaro, all improvements,
inventions, designs, ideas, works of authorship, copyrightable works,
discoveries, trademarks, copyrights, trade secrets, formulas, processes,
structures, product concepts, marketing plans, strategies, customer lists,
information about Lakaro's or the Affiliates' employees and/or consultants
(including, without limitation, job performance of such employees and/or
consultants), techniques, blueprints, sketches, records, notes, devices,
drawings, know-how, data, whether or not patentable, patent applications,
continuation applications, continuation-in-part applications, file wrapper
continuation applications and divisional applications, made or conceived or
reduced to practice or learned by him, either alone or jointly with others,
during the Term (all said improvements, inventions, designs, ideas, works of
authorship, copyrightable works, discoveries, trademarks, copyrights, trade
secrets, formulas, processes, structures, product concepts, marketing plans,
strategies, customer lists, information about Lakaro's or the Affiliates'
employees and/or consultants, techniques, blueprints, sketches, records, notes,
devices, drawings, know-how, data, patent applications, continuation
applications, continuation-in-part applications, file wrapper continuation
applications and divisional applications shall be collectively hereinafter
called "Inventions").

         (b) The Treasurer agrees that all Inventions shall be the sole property
of Lakaro to the maximum extent permitted by applicable law and to the extent
permitted by law shall be "works made for hire" as that term is defined in the
United States Copyright Act (17 USCA, Section 101). Lakaro shall be the sole
owner of all patents, copyrights, trade secret rights, and other intellectual
property or other rights in connection therewith. Treasurer hereby assigns to
Lakaro all right, title and interest he may have or acquire in all Inventions.
Treasurer further agrees to assist Lakaro in every proper way (but at Lakaro's
expense) to obtain and from time to time enforce patents, copyrights or other
rights on said Inventions in any and all countries, and to that end the
Treasurer will execute all documents necessary:

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                  (i) to apply for, obtain and vest in the name of Lakaro alone
(unless Lakaro otherwise directs) letters patent, copyrights or other analogous
protection in any country throughout the world and when so obtained or vested to
renew and restore the same; and

                  (ii) to defend any opposition proceedings in respect of such
applications and any opposition proceedings or petitions or applications for
revocation of such letters patent, copyright or other analogous protection.

         (c) The Treasurer's obligation to assist Lakaro in obtaining and
enforcing patents and copyrights for the Inventions in any and all countries
shall continue beyond the Term, but Lakaro agrees to compensate the Treasurer at
his normal and usual rate after the expiration of the Term for time actually
spent by the Treasurer at Lakaro's request on such assistance.

9.       NON-SOLICITATION

         During the Term, and for 12 months thereafter, Treasurer shall not,
directly or indirectly, without the prior written consent of Lakaro:

         (a) solicit or induce any employee of Lakaro or any Affiliate to leave
the employ of Lakaro or any Affiliate or hire for any purpose any employee of
Lakaro or any Affiliate or any employee who has left the employment of Lakaro or
any Affiliate within six months of the termination of said employee's employment
with Lakaro; or

         (b) solicit or accept employment or be retained by any party who, at
any time during the Term, was a customer or supplier of Lakaro or any Affiliate
where his position will be related to the business of Lakaro; or

         (c) solicit or accept the business of any customer or supplier of
Lakaro or any Affiliate with respect to products similar to those supplied by
Lakaro.

10.      TERMINATION

         (a) This Treasurer's employment hereunder shall begin on the Effective
Date and shall continue for the period set forth in Section 2 hereof unless
sooner terminated upon the first to occur of the following events:

                  (i)      (A) The death of the Treasurer; or

                           (B) the total disability of the Treasurer.

                  (ii) Termination by the Board of Directors of Lakaro for just
cause. Any of the following actions by the Treasurer shall constitute just
cause:

                           (A) Material breach by the Treasurer of Sections 5,
                           6, 7, 8, or 9 of this Agreement; or

                           (B) Material breach by the Treasurer of any provision
                           of this Agreement other than Sections 5, 6, 7, 8 or 9
                           which is not cured by the Treasurer within 30 days of
                           notice from Lakaro; or in the event the breach is not
                           curable within 30 days; the commencement of action(s)
                           to cure within said 30 days and the diligent pursuit
                           of the cure thereafter, provided such breach may be
                           completely cured; or

                           (C) Any action by the Treasurer constituting gross
                           negligence, recklessness or willful misconduct in
                           respect of the Treasurer's obligation to Lakaro which
                           has or is likely to result in material, economic
                           damage to Lakaro.

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                  (iii) Termination by the Treasurer for just cause. Any of the
following actions or omissions by Lakaro shall constitute just cause.

                           (A) Material breach by Lakaro of any provision of
                           this Agreement which is not cured by Lakaro within 30
                           days of notice thereof from the Treasurer; or

                           (B) A failure to elect or reelect the Treasurer to
                           the office of Treasurer of Lakaro or other change by
                           Lakaro of the Treasurer's function, duties or
                           responsibilities such that the Treasurer is no longer
                           the highest ranking Officer of Lakaro; or

                           (C) A "change in control," which shall mean a merger
                           or consolidation in which either more than 50% of the
                           voting power of Lakaro is transferred or Lakaro is
                           not the surviving entity, or sale or other
                           disposition of all or substantially all the assets of
                           Lakaro; or

                           (D) Termination of the Treasurer's employment other
                           than for serious, willful misconduct in respect of
                           the Treasurer's obligations to the Corporation,
                           including, but not limited to, final conviction for a
                           felony or perpetration of a common-law fraud which
                           has or is likely to result in material economic
                           damage to the Corporation; or

                           (E) Relocation to a geographic area without the
                           Treasurer's prior consent.

                  (iv) Termination by Lakaro without cause. Notwithstanding
anything in this Agreement, Lakaro may terminate the Treasurer's employment
without cause upon 90 days prior notice.

         (b) Upon termination by Lakaro for any reason other than the reasons
set forth in subparagraph (i) or (ii) of paragraph (a) above, or upon
termination by the Treasurer for any reason set forth in subparagraph (iii) of
paragraph (a) above, then the Options shall immediately vest and become
exercisable at the option of the Treasurer.

11.      NOTICES

         Any notice or other communication under this Agreement shall be in
writing and shall be deemed to have been given: when delivered personally
against receipt thereof; one (1) business day after being sent by Federal
Express or similar overnight delivery; or three (3) business days after being
mailed registered or certified mail, postage prepaid, return receipt requested,
to either party at the address set forth above, or to such other address as such
party shall give by notice hereunder to the other party.

12.      SEVERABILITY OF PROVISIONS

         If any provision of this Agreement shall be declared by a court of
competent jurisdiction to be invalid, illegal or incapable of being enforced in
whole or in part, the remaining conditions and provisions or portions thereof
shall nevertheless remain in full force and effect and enforceable to the extent
they are valid, legal and enforceable, and no provision shall be deemed
dependent upon any other covenant or provision unless so expressed herein.

13.      ENTIRE AGREEMENT MODIFICATION

         This Agreement contains the entire agreement of the parties relating to
the subject matter hereof, and the parties hereto have made no agreements,
representations or warranties relating to the subject matter of this Agreement
which are not set forth herein. No modification of this Agreement shall be valid
unless made in writing and signed by the parties hereto.

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14.      BINDING EFFECT

         The rights, benefits, duties and obligations under this Agreement shall
inure to, and be binding upon, Lakaro, its successors and assigns, and upon the
Treasurer and his legal representatives. This Agreement constitutes a personal
service agreement, and the performance of the Treasurer's obligations hereunder
may not be transferred or assigned by the Treasurer.

15.      NON-WAIVER

         The failure of either party to insist upon the strict performance of
any of the terms, conditions and provisions of this Agreement shall not be
construed as a waiver or relinquishment of future compliance therewith, and said
terms, conditions and provisions shall remain in full force and effect. No
waiver of any term or condition of this Agreement on the part of either party
shall be effective for any purpose whatsoever unless such waiver is in writing
and signed by such party.

16.      GOVERNING LAW

         This Agreement shall be governed by, and construed and interpreted in
accordance with, the laws of the State of New York without regard to principles
of conflicts of law. Any litigation commenced pursuant to the terms of the
Agreement shall only be prosecuted and defended in the city, county and state of
New York. Additionally, the prevailing party in any litigation shall be entitled
to an additional award of the recoupment of its attorney fees, cost and
expenses.

17.      REMEDIES FOR BREACH

         The Treasurer understands and agrees that any breach of Sections 5, 6,
7, 8 or 9 of this Agreement by the Executive could cause irreparable damage to
Lakaro and to the Affiliates, and that monetary damages alone would not be
adequate and, in the event of such breach, Lakaro shall have, in addition to any
and all remedies of law, the right to an injunction, specific performance or
other equitable relief to prevent or redress the violation of Lakaro's rights
under such Sections.

18.      HEADINGS

         The headings of paragraphs are inserted for convenience and shall not
affect any interpretation of this Agreement.

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the day and year first above written.

                                            EMPLOYEE:



                                            By:    /s/ Ira Weinstein
                                                   ---------------------------
                                            Name:  Ira Weinstein



                                            LAKARO BIOPHARMACEUTICALS, INC.



                                            By:     /s/ Morris Laster
                                                    --------------------------
                                            Name:   Morris Laster
                                            Title:  Chief Executive Officer