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EXHIBIT 31.1

Certification Pursuant to Section 302 of the
Sarbanes-Oxley Act of 2002

I, Michael M. Lee, certify that:

|1. | I have reviewed this Quarterly Report on Form 10-Q of
      AlphaRx, Inc.;                                                                                                                                                                                                                                                                                  
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|2. | Based on my knowledge, this report does not contain any
      untrue statement of a material fact or omit to state a material fact
      necessary to make the statements made, in light of the circumstances under
      which such statements were made, not misleading with respect to the period
      covered by this report;                          
|   |                                                                                                                                                                                                                                                                                                                                                             
|3. | Based on my knowledge, the financial statements, and other
      financial information included in this report, fairly present in all
      material respects the financial condition, results of operations and cash
      flows of the registrant as of, and for, the periods presented in this
      report;                                             
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|4. | The registrants other certifying officer and I are
      responsible for establishing and maintaining disclosure controls and
      procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and
      internal control over financial reporting (as defined in Exchange Act
      Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
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|   | a.                                                                                                                                                                                                                                                                                                                                                          
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|   | b.                                                                                                                                                                                                                                                                                                                                                          
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|   | c.                                                                                                                                                                                                                                                                                                                                                          
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|   | d.                                                                                                                                                                                                                                                                                                                                                          
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|5. | The registrants other certifying officer and I have
      disclosed, based on our most recent evaluation of internal control over
      financial reporting, to the registrants auditors and the audit committee
      of the registrants board of directors (or persons performing the
      equivalent functions):                                     
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|   | a.                                                                                                                                                                                                                                                                                                                                                          
|   |                                                                                                                                                                                                                                                                                                                                                             
|   | b.                                                                                                                                                                                                                                                                                                                                                          

Date: February 14, 2011

/s/ Michael LeeMichael Lee,
Chief Executive Officer, Interim Chief Financial Officer and Director
(Principal Executive and Financial Officer)

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