102900 Federal Register / Vol. 89, No. 243 / Wednesday, December 18, 2024 / Notices 

If you are interested in information 

that is not included in these tables, you 

may contact EPA’s technical 

information contact or general 

information contact as described under 

FOR FURTHER INFORMATION CONTACT to 

access additional non-CBI information 

that may be available. 

Authority: 15 U.S.C. 2601 et seq. 

Dated: December 12, 2024. 

Pamela Myrick, 

Director, Project Management and Operations 

Division, Office of Pollution Prevention and 

Toxics. 

[FR Doc. 2024–29934 Filed 12–17–24; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPPT–2023–0601; FRL–11581– 

07–OCSPP] 

High-Priority Substance Designations 

Under the Toxic Substances Control 

Act (TSCA) and Initiation of Risk 

Evaluation on High-Priority 

Substances; Notice of Availability 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: Under the Toxic Substances 

Control Act (TSCA) and related 

implementing regulations, EPA is 

designating five chemicals as HighPriority Substances for risk evaluation. 

This document provides the identity of 

five chemical substances for final 

designation as High-Priority Substances 

for risk evaluation, EPA’s rationale for 

final designation as High-Priority 

Substances, and instructions on how to 

access the chemical-specific 

information, analysis, and basis EPA 

used to support final designations for 

the chemical substances. A designation 

of a substance as a High-Priority 

Substance is not a finding of 

unreasonable risk. Rather, the 

designation of these chemical 

substances as high priority constitutes 

the initiation of evaluation of associated 

risk. 

DATES: The designations of High-Priority 

Substances for risk evaluation in this 

notice are effective December 18, 2024. 

ADDRESSES: The docket for this action, 

identified by docket identification (ID) 

number EPA–HQ–OPPT–2023–0601, is 

available online at https://

www.regulations.gov. In addition, the 

docket ID numbers for the individual 

chemical substances designated in Unit 

IV. are as follows: Acetaldehyde (EPA– 

HQ–OPPT–2018–0497); Acrylonitrile 

(EPA–HQ–OPPT–2018–0449); 

Benzenamine (EPA–HQ–OPPT–2018– 

0474); Vinyl Chloride (EPA–HQ–OPPT– 

2018–0448); and 4,4′-Methylene bis (2- 

chloroaniline) (MBOCA) (EPA–HQ– 

OPPT–2018–0464). Additional 

information about dockets generally, 

along with instructions for visiting the 

docket in-person, is available at https:// 

www.epa.gov/dockets. 

FOR FURTHER INFORMATION CONTACT: 

For technical information: Sarah Au, 

Data Gathering, Management and Policy 

Division (7406M), Office of Pollution 

Prevention and Toxics, Environmental 

Protection Agency, 1200 Pennsylvania 

Ave. NW, Washington, DC 20460–0001; 

telephone number: (202) 564–0398; 

email address: au.sarah@epa.gov. 

For general information: The TSCAHotline, ABVI-Goodwill, 422 South 

Clinton Ave., Rochester, NY 14620; 

telephone number: (202) 554–1404; 

email address: TSCA-Hotline@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. Executive Summary 

A. Does this action apply to me? 

This action is directed to the public 

in general and may be of interest to 

entities that currently or may 

manufacture (including import) a 

chemical substance regulated under 

TSCA (e.g., entities identified under 

North American Industrial 

Classification System (NAICS) codes 

325 and 324110). The action may also 

be of interest to chemical processors, 

distributors in commerce, and users, 

non-governmental organizations in the 

environmental and public health 

sectors, state and local government 

agencies, Tribes, and members of the 

public. Since other entities may also be 

interested, EPA has not attempted to 

describe all the specific entities and 

corresponding NAICS codes for entities 

that may be interested in or affected by 

this action. 

B. What action is the Agency taking? 

EPA is finalizing the designation of 

five chemical substances as HighPriority Substances for risk evaluation 

pursuant to section 6(b) of TSCA, 15 

U.S.C. 2605(b). This document includes 

a high-level summary of comments 

received during the two 90-day 

comment periods during which the 

public submitted comments on EPA’s 

initiation of prioritization (Ref. 1) and 

the proposed designations of those five 

chemicals as High-Priority Substances 

for risk evaluation (Ref. 2), as well as a 

high-level summary of Agency 

responses to those comments received 

during both 90-day public comment 

periods. The comments and EPA’s 

responses are discussed in more depth 

in the response to comments document 

(Ref. 3). EPA also considered comments 

received during and following the 

prioritization public webinar that 

occurred in February 2024, during 

which EPA explained the prioritization 

process and provided an overview of 

information that may be used to inform 

the considerations that ultimately 

support a High- or Low-Priority 

Substance designation, such as 

information on conditions of use and 

health effects resulting from exposure to 

the chemicals of interest. 

C. Why is the Agency taking this action? 

TSCA section 6(b) and implementing 

regulations at 40 CFR part 702, subpart 

A require EPA to carry out a 

prioritization process for chemical 

substances that may be designated as 

high priority for risk evaluation. EPA 

generally expects to complete five risk 

evaluations per year over the next 

several years, and TSCA section 

6(b)(3)(C) requires EPA to designate at 

least one High-Priority Substance upon 

completion of each risk evaluation for a 

High-Priority Substance. Pursuant to 

TSCA section 6(b)(2)(B), EPA is 

finalizing the designation of the five 

chemical substances as High-Priority 

Substances for risk evaluation identified 

as candidates for High-Priority 

Substance designation when EPA 

initiated the prioritization process on 

December 18, 2023 (Ref. 1). As required 

under TSCA section 6(b)(3)(C), EPA is 

specifying the designation of: MBOCA 

to replace the final risk evaluation for 

1,1-dichloroethane; acetaldehyde to 

replace the final risk evaluation for 1,3- 

butadiene; acrylonitrile to replace the 

final risk evaluation for dicyclohexyl 

phthalate; benzenamine to replace the 

final risk evaluation for formaldehyde; 

and vinyl chloride to replace the final 

risk evaluation for tris(2-chloroethyl) 

phosphate. 

D. What is the Agency’s authority for 

taking this action? 

This document is issued pursuant to 

TSCA section 6(b)(1) and 6(b)(3)(C). 

E. What are the estimated incremental 

impacts of this action? 

This document identifies the five 

chemical substances for which EPA is 

initiating the risk evaluation process 

and the five chemical substances that 

have already or will have risk 

evaluations completed which they will 

replace. This document does not 

establish any requirements on persons 

or entities outside of the Agency. No 

incremental impacts are therefore 

anticipated, and consequently EPA did 


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Federal Register / Vol. 89, No. 243 / Wednesday, December 18, 2024 / Notices 102901 

not estimate potential incremental 

impacts for this action. 

II. Background 

TSCA section 6(b)(1) requires EPA to 

prioritize chemical substances for risk 

evaluation. In accordance with TSCA 

section 6(b) and 40 CFR 702.7, on 

December 18, 2023 (Ref. 1) EPA 

initiated the prioritization process for 

five chemical substances identified as 

candidates for High-Priority Substance 

designation. On July 25, 2024, EPA 

proposed to designate the same five 

chemical substances as High-Priority 

Substances for risk evaluation (Ref. 2). 

That notice included a summary of the 

approach used by EPA to support the 

proposed designations, links to the 

proposed designation document for 

each of the chemical substances, and 

instructions on how to access the 

chemical-specific information, analysis, 

and basis EPA used to make the 

proposed designation for each chemical 

substance. 

Under TSCA section 6(b)(1)(B) and 

implementing regulations (40 CFR 

702.3), a High-Priority Substance is 

defined as ‘‘a chemical substance that 

EPA concludes, without consideration 

of costs or other non-risk factors, may 

present an unreasonable risk of injury to 

health or the environment because of a 

potential hazard and a potential route of 

exposure under the conditions of use, 

including an unreasonable risk to a 

potentially exposed or susceptible 

subpopulation identified as relevant by 

EPA.’’ 

A designation of a substance as a 

High-Priority Substance is not a finding 

of unreasonable risk. Rather, when 

prioritization is complete, for those 

chemicals designated as High-Priority 

Substances, the Agency will have 

evidence on hazards and exposures that 

supports a finding that the substances 

may present an unreasonable risk of 

injury to health or the environment 

under the conditions of use. Final 

designation of a High-Priority Substance 

initiates the risk evaluation process (40 

CFR 702.17), which culminates in a 

finding of whether the chemical 

substance presents an unreasonable risk 

of injury to health or the environment 

under the conditions of use. 

As described in the notice proposing 

to designate the five chemical 

substances as High-Priority Substances 

for risk evaluation (Ref. 2), ‘‘EPA will 

generally use reasonably available 

information to screen the candidate 

chemical substance[s] against the 

following criteria and considerations: 

• The chemical substance’s hazard 

and exposure potential; 

• The chemical substance’s 

persistence and bioaccumulation; 

• Potentially exposed or susceptible 

subpopulations; 

• Storage of the chemical substance 

near significant sources of drinking 

water; 

• The chemical substance’s 

conditions of use or significant changes 

in conditions of use; 

• The chemical substance’s 

production volume or significant 

changes in production volume; and 

• Other risk-based criteria that EPA 

determines to be relevant to the 

designation of the chemical substance’s 

priority’’ (40 CFR 702.9(a)). 

When selecting candidates for 

prioritization, the Agency also generally 

intends to consider (1) Agency priorities 

(with consideration of the priorities of 

other Federal agencies), (2) Quantity 

and quality of information (to ensure 

that information necessary to prioritize 

the substance is reasonably available), 

and (3) Overall workload (the Agency 

will be mindful of the complexity 

associated with the assessment of the 

chemical substance to ensure timely 

completion of prioritization and risk 

evaluation of each substance) (Ref. 5). 

A more detailed discussion of the 

information, analysis, and basis used to 

support the proposed High-Priority 

Substance designation can be found in 

Unit IV.A of the July 25, 2024, notice 

(Ref. 2). 

As described in 40 CFR 702.9(b), in 

conducting the screening review during 

the prioritization process, EPA 

considered sources of reasonably 

available information relevant to the 

review criteria as outlined in the statute 

(TSCA section 6(b)(1)(A)) and 

implementing regulations (40 CFR 

702.9(a)) and consistent with the 

scientific standards of TSCA section 

26(h), including, as appropriate, sources 

for hazard and exposure data listed in 

Appendices A and B of the ‘‘TSCA 

Work Plan Chemicals: Methods 

Document’’ (February 2012), and did 

not consider costs or other non-risk 

factors in making a proposed HighPriority Substance designation (see 

TSCA Section 6(b) and 40 CFR 702.9). 

After considering additional 

information collected from the proposed 

designation process, described in Unit 

III., EPA is finalizing the High-Priority 

Substance designations of the same five 

chemical substances proposed for HighPriority Substance designations, 

consistent with the scientific standards 

of TSCA section 26(h) and (i). EPA did 

not consider costs or other non-risk 

factors in making the final priority 

designations. Instructions on how to 

access the chemical-specific 

information, analysis, and basis used by 

EPA to support the final designation for 

each chemical substance can be found 

in Unit IV. A general statement of the 

condition(s) of use that were the 

primary basis for each designation is 

contained in Unit IV. Pursuant to TSCA 

section 6(b)(3)(A) and 40 CFR 702.17, 

the designation of these chemical 

substances as High-Priority Substances 

constitutes the initiation of the risk 

evaluations on the substances. 

III. Information and Comments 

Received 

A. Overview of Public Comments 

EPA provided a 90-day comment 

period for the public to submit 

comments on the list of candidate HighPriority Substances immediately 

following the initiation of prioritization 

(Ref. 1) and provided a second 90-day 

comment period for the public to submit 

comments on the documents supporting 

the proposed designations of HighPriority Substances for risk evaluation 

(Ref. 2). The two comment periods are 

required by TSCA section 6(b)(1)(C) and 

implementing regulations (40 CFR 

702.7(d) and 702.9(g)). 

Under TSCA section 6(b)(1)(C)(i), EPA 

must ‘‘request interested persons to 

submit relevant information on a 

chemical substance that EPA has 

initiated the prioritization process on, 

before proposing a priority designation 

for the chemical substance, and provide 

90 days for such information to be 

provided’’ (Ref. 1). At initiation of the 

prioritization process, EPA published a 

Federal Register notice identifying five 

chemical substances and provided a 

general explanation for why the Agency 

chose to initiate prioritization on those 

chemical substances. During this 

comment period, the public was invited 

to submit relevant information on the 

chemical substances undergoing 

prioritization, including, but not limited 

to, any information that may inform the 

screening review conducted pursuant to 

40 CFR 702.9(a). The information 

received was considered when 

developing the proposed designations 

for the High-Priority Substances. The 

required 90-day comment period was 

extended for an additional 30 days to 

receive chemical-specific comments and 

information for MBOCA (docket ID No. 

EPA–HQ–OPPT–2018–0464). The 

second 90-day comment period 

following the proposed High-Priority 

Substance designations of the same five 

chemical substances identified as 

candidates for High-Priority Substance 

designation. Under TSCA section 

6(b)(1)(C)(ii), EPA must ‘‘publish each 

proposed designation of a chemical 


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102902 Federal Register / Vol. 89, No. 243 / Wednesday, December 18, 2024 / Notices 

substance as a High- or Low-Priority 

Substance, along with an identification 

of the information, analysis, and basis 

used to make the proposed designations, 

and provide 90 days for public comment 

on each such proposed designation’’ 

(Ref. 2). The Federal Register notice 

proposing the designations of these 

substances as High-Priority for risk 

evaluation identified how to access the 

chemical-specific information, analysis, 

and basis used to support the proposed 

designations and announced the 

availability of a proposed designation 

document for each of the chemical 

substances undergoing prioritization. 

Interested persons were invited to 

submit comments, including additional 

information relevant to the chemical 

substances that were proposed as high 

priority for risk evaluations. 

To the extent that comments from the 

first comment period provided 

information on additional conditions of 

use for the candidate High-Priority 

Substances, those conditions of use 

were discussed in the proposed 

designation documents for each 

chemical substance. Other information 

received specific to High-Priority 

Substances (e.g., relevant studies and 

assessments) was considered when 

making the final priority designations 

and will be considered as reasonably 

available information in the subsequent 

risk evaluation for each High-Priority 

Substance. 

Following a public webinar on 

February 20, 2024, EPA also received 

comments on the prioritization process 

and data considered up until that date 

for the five chemical substances for 

which EPA initiated prioritization in 

December 2023. The comments received 

were considered when developing the 

proposed and final designations for the 

High-Priority Substances. 

EPA created one general docket to 

receive comments regarding the 

prioritization process (docket ID No. 

EPA–HQ–OPPT–2023–0601) and 

additional dockets to receive chemicalspecific information (as identified under 

ADDRESSES). During the first public 

comment period, EPA also opened the 

pre-prioritization docket (docket ID No. 

EPA–HQ–OPPT–2023–0606) to 

welcome potentially relevant 

information and comments on the 

candidate chemical substances that 

were not selected for prioritization. 

EPA received 96,011 comment 

submissions to inform prioritization; 

several of these comments were mass 

mailing campaigns with identical 

submissions. There were also many 

comments that could not be posted 

publicly due to inappropriate language, 

copyright violations, and empty 

submissions. Upon review, EPA 

received 977 unique submissions across 

both public comment periods. Some 

commenters included comments for 

multiple chemical substances in one 

submission and submitted the same 

comment to multiple dockets while 

other commenters chose to submit 

different sets of comments to each 

chemical-specific docket. EPA received 

submissions from individuals, Tribes, 

potentially affected businesses or trade 

associations, environmental and public 

health advocacy groups, academia, and 

other organizations. Comments 

addressed the overall prioritization 

process (e.g., the collection and 

consideration of relevant information, 

basis for designation, etc.), the review 

process (e.g., the use of data and 

approaches for screening review), 

information specific to the candidate 

chemical substances (e.g., relevant 

studies, previous assessments, and 

conditions of use information), as well 

as topics beyond the scope of this 

prioritization action or not related to the 

prioritization process in general (e.g., 

scheduling future chemicals for 

prioritization, risk evaluation, and risk 

management). EPA also received a few 

comments which were not related to 

TSCA. All comments received are 

identified by their respective docket ID 

number and are available at https://

www.regulations.gov. 

EPA responded to comments related 

to the High-Priority Substance 

designations in two general categories: 

(1) General comments, including 

overarching and cross-cutting policy 

and process comments, received for the 

candidate High-Priority Substance 

designations; and (2) Chemical-specific 

comments received on each proposed 

High-Priority Substance designation 

(Ref. 3). A high-level summary of the 

comments received related to the 

prioritization process and Agency 

responses follows in this unit. The 

comments and the Agency’s responses 

are discussed in more depth in the 

response to comments document (Ref. 

3), a copy of which is included in 

docket ID No. EPA–HQ–OPPT–2023– 

0601. 

B. Comments on Candidate HighPriority Designations 

EPA received 748 unique comments 

during the first public comment period 

between December 18, 2023, and March 

18, 2024, and 229 unique comments 

during the second comment period from 

July 25, 2024, to October 23, 2024, 

resulting in a total of 977 unique 

comment submissions. An additional 

two comment submissions were 

received for MBOCA during the 30-day 

extension of the first public comment 

period for Docket ID number: EPA–HQ– 

OPPT–2018–0464. 

EPA received several mass-mailing 

campaigns, totaling over 13,000 

signatures. All mass-mailing campaigns 

expressed their support for the 

prioritization process and encouraged 

EPA to prioritize one or all of the 

chemicals. Specifically, many of the 

mass mailing campaigns encouraged 

EPA to designate vinyl chloride as a 

High-Priority Substance under TSCA. In 

addition to the mass-mailing campaigns 

and 17 commenters who attended the 

prioritization public webinars in 

February 2024, EPA received over 100 

comments expressing support for EPA’s 

prioritization actions. 

Commenters expressed their concern 

regarding human health hazards and 

exposure potential of all five of the 

High-Priority Substances and asked that 

EPA consider specific potential health 

outcomes and exposure scenarios. 

Several commenters urged EPA to 

identify relevant potentially exposed or 

susceptible subpopulations (PESS), 

including infants, children, pregnant 

women, workers, the elderly, and 

people living in proximity to sources of 

contamination, as well as consider 

environmental justice concerns in the 

prioritization process. In addition, 

several commenters, including some of 

the mass-mailing campaigns, urged the 

Agency to consider all potential 

exposures and risks, including those 

from accidents, spills, and leaks, 

specifically potential exposure resulting 

from transportation incidents such as 

derailments and collisions, which may 

pose significant risk to fence line 

communities. 

Over 600 commenters asked EPA to 

ban vinyl chloride and emphasized the 

availability of hazard and exposure data 

demonstrating harm posed by vinyl 

chloride releases. Many commenters 

also cited the February 3, 2023, train 

derailment that resulted in the release of 

and potential exposure to vinyl chloride 

by residents in East Palestine, Ohio. 

Each data submission and potentially 

relevant data source was screened using 

systematic review approaches for 

applicability and considered for the 

final designation of these chemical 

substances as High-Priority Substances 

and will be considered as reasonably 

available information. 

The Agency appreciates all comments 

and information submitted by the public 

for this action. For additional 

information regarding specific topics 

and EPA’s responses to these comments, 

please see the Agency’s full response to 

comments received (Ref. 3). 


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Federal Register / Vol. 89, No. 243 / Wednesday, December 18, 2024 / Notices 102903 

IV. Designation as High-Priority 

Substances for Risk Evaluation 

Based on the information provided in 

the proposed designation documents, as 

referenced in the document that 

appeared in the Federal Register of July 

25, 2024 (Ref. 2), and public comments 

received, including information 

pertaining to individual chemical 

substances, EPA is designating the same 

five chemicals as High-Priority 

Substances for risk evaluation under 

TSCA. Pursuant to 40 CFR 702.11, 

which states: ‘‘For High-Priority 

Substances, EPA generally expects to 

indicate which condition(s) of use were 

the primary basis for such 

designations.’’ For all five High-Priority 

Substances the conditions of use which 

formed the primary basis for the 

designation were included in the 

proposed designation documents. The 

final High-Priority Substance 

designations are as follows: 

• Acetaldehyde, CASRN 75–07–0, 

Docket ID number: EPA–HQ–OPPT– 

2018–0497; 

• Acrylonitrile, CASRN 107–13–1, 

Docket ID number: EPA–HQ–OPPT– 

2018–0449; 

• Benzenamine, CASRN 62–53–3, 

Docket ID number: EPA–HQ–OPPT– 

2018–0474; 

• Vinyl chloride, CASRN 75–01–4, 

Docket ID number: EPA–HQ–OPPT– 

2018–0448; and 

• 4,4′-Methylene bis(2-chloroaniline) 

(MBOCA), CASRN 101–14–4, Docket ID 

number: EPA–HQ–OPPT–2018–0464. 

The final designations are based on 

the conclusion that each chemical 

substance satisfies the definition of 

High-Priority Substance in TSCA 

section 6(b)(1)(B) and 40 CFR 702.3. 

EPA developed a document for each 

substance to identify the information, 

analysis and basis used to support the 

proposed designations as a High-Priority 

Substance for risk evaluation. These 

documents are available in the docket of 

each of the chemical substances. Also 

included in each document is an 

explanation of the approach used by 

EPA to conduct the review. Each 

document includes an overview of the 

requirements in TSCA section 6(b)(1)(A) 

and a regulatory section addressing the 

review criteria and considerations (40 

CFR 702.9). 

These designated High-Priority 

Substances will fulfill the statutory 

requirement to designate at least one 

high-priority substance upon 

completion of each risk evaluation for a 

High-Priority Substance, under TSCA 

section 6(b)(3)(C). Pursuant to TSCA 

section 6(b)(3)(A) and 40 CFR 702.17, 

the designation of these chemical 

substances as High-Priority Substances 

constitutes the initiation of the risk 

evaluations on the substances. 

A designation of a chemical substance 

as a High-Priority Substance is not a 

finding of unreasonable risk; rather, a 

final designation as a High-Priority 

Substance initiates the risk evaluation 

for the chemical substance. This is a 

three-year process that will culminate in 

a finding of whether or not the chemical 

substance presents an unreasonable risk 

of injury to health or the environment 

under the conditions of use. The 

chemical-specific designation 

documents containing the information, 

analysis and basis used to support the 

proposed designations are located in the 

docket for each chemical substance. As 

previously discussed, to the extent that 

comments provided information on 

additional conditions of use for the 

candidate High-Priority Substances for 

risk evaluation, those conditions of use 

were noted in the proposed designation 

documents for each chemical substance 

and may be reflected in the draft scope 

of the risk evaluation for each chemical 

substance, which will include the 

conceptual model and analysis plan for 

carrying out the evaluation. As such, 

EPA will not amend the proposed 

designation documents. Instead, 

additional submitted potentially 

relevant information specific to HighPriority Substances (e.g., relevant 

studies and assessments) will be 

considered in subsequent phases of risk 

evaluation, including draft scope 

documents and draft risk evaluation 

documents, both of which will be 

subject to public comment 

opportunities. 

V. References 

The following is a listing of the 

documents that are specifically 

referenced in this document. The docket 

for this action includes these documents 

and other information considered by 

EPA, including documents that are 

referenced within the documents that 

are included in the docket. For 

assistance in locating these referenced 

documents, please consult the technical 

person listed under FOR FURTHER

INFORMATION CONTACT. 

1. EPA. Initiation of Prioritization Under the 

Toxic Substances Control Act (TSCA). 

Notice. Federal Register. 88 FR 87423, 

December 18, 2023 (FRL–11581–01– 

OCSPP). 

2. EPA. Proposed High-Priority Substance 

Designations Under the Toxic 

Substances Control Act (TSCA). Federal 

Register. 89 FR 60420, July 25, 2024 

(FRL–11581–03–OCSPP). 

3. EPA. EPA Response to Public Comments 

Received on the ‘‘Initiation of 

Prioritization Under the Toxic 

Substances Control Act’’ and ‘‘Proposed 

High-Priority Substance Designations 

Under the Toxic Substances Control 

Act.’’ December 18, 2024. 

4. EPA. ‘‘A Working Approach for Identifying 

Potential Candidate Chemicals for 

Prioritization.’’ (https://www.epa.gov/ 

sites/production/files/201809/ 

documents/preprioritization_white_

paper_9272018.pdf). September 27, 

2018. 

Authority: 15 U.S.C. 2601 et seq. 

Dated: December 12, 2024. 

Michal Freedhoff, 

Assistant Administrator, Office of Chemical 

Safety and Pollution Prevention. 

[FR Doc. 2024–29830 Filed 12–17–24; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[EPA–HQ–OPPT–2023–0601; FRL–11581– 

06–OCSPP] 

Initiation of Prioritization Under the 

Toxic Substances Control Act (TSCA); 

Notice of Availability 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: Under the Toxic Substances 

Control Act (TSCA) and related 

implementing regulations, EPA is 

initiating the prioritization process for 

five chemical substances as candidates 

for designation as High-Priority 

Substances for risk evaluation. This 

action provides the identity of the 

chemical substances being initiated for 

prioritization, a general explanation of 

why the Agency chose these chemical 

substances, and information on the data 

sources EPA plans to use to support the 

designation. EPA is providing a 90-day 

comment period, during which 

interested persons may submit relevant 

information on these chemical 

substances. 

DATES: Comments must be received on 

or before March 18, 2025. 

ADDRESSES: Submit your comments, 

identified by docket identification (ID) 

number, through https://

www.regulations.gov. Follow the online 

instructions for submitting comments. 

For comments not related to a specific 

chemical, including general comments 

on Unit IV.A., use docket ID number 

EPA–HQ–OPPT–2023–0601; submit 

information on the candidates for which 

EPA is initiating the prioritization 

process to the applicable chemicalspecific docket ID number identified in 

Unit III.B.; submit information on the 

potential candidates for which EPA is 

not currently initiating the prioritization 


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