Research and Development contract


    Exhibit
      10.1

     

    Page 1
      of 15

     

    

    
 

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page
      2 of 15

     

    Section
      B
      - Supplies or Services and Prices

    


    B.1. TYPE
      OF
      CONTRACT

    This
      is a
      cost plus fixed fee completion form type contract pursuant to FAR
      16.306(d)(1).

    


    B.2.
      The
      cost principles and procedures in subpart 31.103 of the Federal Acquisition
      Regulation (FAR) are incorporated by reference for determining reimbursable
      costs per FAR 31.2 as appropriate.

    


    
 

    
      	
              ITEM
                NO

            	
              SUPPLIES/SERVICES

            	
              QUANTITY

            	
              UNIT

            	
              UNIT
                PRICE

            	
              AMOUNT

            
	
              0001

            	 	 	 	 	 
	 	
              BAA
                Effort

               

              CPFF

               

              BAA
                Effort as set forth in the SOW and the Contractor's proposal. The
                contractor, as an independent contractor and not as an agent of the
                Government, shall furnish the necessary resources (except those
                specifically designated as Government-furnished) to perform the work
                as
                detailed in the Broad Agency Announcement proposal entitled: "Development
                of a CMOS Microarray Platform for Bio and Chemical Threat Agent
                Detection", specifically pages 5-10, dated 1 Sep 2006, and submitted
                by
                CombiMatrix.

               

              FOB:
                Destination

               

               

            	 
	
              ESTIMATED
                COST

               

            	
              $2,083,085.00

            
	
              FIXED
                FEE

            	
              $129,432.00

            
	
               

              TOTAL
                EST COST + FEE

            	
              $2,212,517.00

            
	 	
              ACRN
                AA

              CIN:
                000000000000000000000000000000

               

            	
              $2,212,517.00

            


    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 3
      of 15


    Section
      C
      - Descriptions and Specifications

    


    OTHER
      INFORMATION

    SECTION
      C: DESCRIPTION/SPECIFICATIONS/WORK STATEMENTS

    


    TITLE:
      Development
      of a CMOS Microarray Platform for Bio and Chemical Threat Agent
      Detection

     

    C.1.0
      Scope.
      This
      work effort encompasses development of a biological and chemical agent point
      detector based on electrochemical detection of agents on CMOS microarrays.
      The
      effort will entail development and production of two
      new
      microarray designs, development and fabrication of a new prototype instrument
      that supports automated sample processing, genomic and serological assays and
      electrochemical
      detection (ECD),
      develop and evaluate different bioinformatics approaches and genomic assays
      for
      detecting specific biothreat agents (BTAs), systems integration of hardware,
      software, and assays for a fully functional and automated bio/chem detection
      system, and validating Quality Assurance and /Quality Control (QA/QC) processes
      to reduce the costs and improve performance of microarrays. 

    


    C.1.1
      Background.
      In the
      Modernization Plan 2004, the JRO-CBRN recognized serious shortcomings in current
      platforms for the point detection of BTAs and chemical threat agents (CTAs)
      .
      Size, weight, ability to detect diverse agents, reduced false alarm rates,
      accuracy, and sensitivity were identified as common problems with current
      technologies. In response, the Defense Threat Reduction Agency (DTRA) is
      emphasizing the optimization of sensor technologies with a focused effort on
      multi-agent sensors for chemical and biological (CB) agents to include
      non-traditional agents, emerging threat agents and toxic industrial
      chemicals/materials. In addition, DTRA has a new nanotechnology initiative
      to
      identify novel nanoscale approaches that can be applied to CB point detection
      array analysis.

     

    C.1.2
      Objective.
      . To
      continue development of an automated biothreat agent (BTA) detection system
      based upon the CombiMatrix complementary metal oxide semiconductor (CMOS)
      microarray and electrochemical detection (ECD); to continue the integration
      of
      serological and genomic assays for orthogonal testing; and to explore new
      methods of detection that expand target identification, reduce reagent burden,
      and improve assay time.

     

    C.2.0
      Applicable
      Documents.
      None.

    


    C.3.0
      Requirements.

    


    C.3.1
      General.
      The
      contractor, as an independent contractor and not as an agent of the Government,
      shall furnish the necessary resources (except those specifically designated
      as
      Government-furnished) to perform the work as detailed in the Broad Agency
      Announcement proposal entitled: “Development of a CMOS Microarray Platform for
      Bio and Chemical Threat Agent Detection”, specifically pages 5-10, dated 1
      September 2006, and submitted by CombiMatrix, Inc.

    


    C.3.2
      Safety.
      

    


    C.3.2.1
      The contractor shall notify all local emergency support agencies (such as law
      enforcement, fire department, health departments and government) of Biological
      Defense Program activities and ensure the appropriate emergency support is
      available to provide effective emergency response. The contractor shall
      formalize all required support agreements with local agencies.

    


    C.3.2.1.2
      The contractor shall notify the government Contracting Officer’s Representative
      of any biological defense mishaps related to this contract within 24 hours.
      No
      government reply is required.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    
Page 4
      of 15

     

    C.3.2.1.3
      The contractor shall make facilities used to support this contract accessible
      to
      government representatives for periodic safety compliance inspections. The
      contractor shall correct all major deficiencies noted during safety compliance
      inspections prior to beginning or continuing operations in accordance with
      the
      government’s instructions.

    


    C.3.2.1.4
      The contractor shall submit a safety assessment report in accordance with
      Exhibit Line Item Number (ELIN) A003. for new developed or modified equipment
      prior to transport to Department of the Army for evaluation.

    


    C.3.3
      Security.

    


    C.3.3.1
      This contract is unclassified and does not contain security requirements or
      a
      Contract Security Classification Specification, DD Form 254. However, the
      Government may require Operational Security (OPSEC) measures (when applicable)
      to protect sensitive unclassified contract information. If access to
      unclassified sensitive information (For Official Use Only - FOUO) is authorized,
      contractor may access only the information related to the subject matter of
      this
      contract.

    


    C.3.3.2
      The contractor shall not use foreign nationals on this contract unless approved
      by the Contracting Officer. When requesting approval, the contractor shall
      furnish full name, date of birth, place of birth, citizenship, registration
      number, type of visa, port of entry, and type of position in which employee
      will
      be utilized. Previously approved foreign nationals must be re-approved if the
      nature of their work under this contract differs from that performed under
      the
      prior year’s contract. The Contractor shall submit a copy of the work visa or
      green card with an abbreviated Curriculum Vitae and a justification to the
      Contract Specialist for review by the Security Office and subsequent approval
      by
      the Contracting Officer. 

    


    C.3.3.3
      Should the government determine that the technology has developed to a point
      where the information warrants protection, a DD Form 254 and an approved
      classification guide will be issued.

    


    C.3.4
      Administration.
      

    


    C.3.4.1
      Reporting.

    


    C.3.4.1.1
      The contractor shall provide progress reports in accordance with (IAW) Exhibit
      Line Item Number (ELIN) A001.

    


    C.3.4.1.2
      The contractor shall provide a final comprehensive report IAW ELIN A002. The
      final report shall include detailed descriptions of the work
      accomplished.

    


    C.3.4.1.2.1
      The contractor shall provide the synthesis procedures and QA/QC procedures
      as
      appendices to the draft final report (IAW ELIN A002). 

    


    C.3.4.1.3
      For any publication of a technical paper or presentation resulting from this
      contract, the Contractor shall make attribution to and include as a co-author
      those Government personnel who made research contributions to the contract
      subject matter being published in the same manner and to the same extent as
      the
      principle author would do so for it’s own peers, assistants, or
      students.

    


    C.3.4.2
      Contractor Manpower Reporting. . The contractor shall perform manpower reporting
      as follows:

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    
Page 5
      of 15

     

    C.3.4.2.1
      The contractor shall report all contractor manpower (including subcontractor
      manpower) required for performance of this contract using the format provided
      at
      the following web address: https://cmra.army.mil.
      The
      contractor shall report directly to the website. The contractor shall include
      the following:

     

    Contract
      Number 

    Delivery
      Order Number (If applicable) 

    Task
      Order Number (If applicable) 

    Requiring
      Activity Unit Identification Code (W1D101)

    Command 
      (Edgewood Chemical Biological Center)

    Contractor
      Contact Information 

    Federal
      Service Code 

    Direct
      Labor Hours 

    Direct
      Labor Dollars 

    Location
      Information

    


    Contract
      Number - Always
      13
      characters long, usually beginning with a unit code, like W911SR. Enter the
      full
      number without dashes.

     
      

    Delivery
      Order Number -
      Usually
      13 characters long. Enter with no dashes. Many contracts have multiple Delivery
      Orders. Each must be entered.

     
      

    Task
      Order Number -
      Usually
      13 characters long. Enter with no dashes. Services contracts are often created
      with Task Orders as opposed to Delivery Orders.

     
      

    Requiring
      Activity UIC -
      The Unit
      Identification Code of the
      unit for which the service is being performed
      -
      meaning the unit the requested the service, which is not necessarily, but may
      be, the unit that contracted for the service. 

     
      

    Command
      -
      From the
      drop down arrow, select the Army Command for the unit reflected in the Requiring
      Activity UIC .

     
      

    Total
      Obligated Dollars -
      The
      total dollar amount obligated during the fiscal year, at the Delivery Order
      or
      Task Order level.

     
      

    Total
      Disbursements -
      The
      total dollar amount disbursed during the fiscal year, at the Delivery Order
      and/or Task Order level.

    


    C.3.4.2.2
      The contractor shall also provide the estimated total cost (if any) (CLIN 0002)
      incurred to comply with this reporting requirement. The reporting period shall
      be the period of performance not to exceed 12 months ending 30 September of
      each
      government fiscal year and must be reported by 31 October of each calendar
      year.The contractor shall perform manpower reporting as follows:

    


    C.3.4.2.3
      The contractor shall report all contractor manpower (including subcontractor
      manpower) required for performance of this contract using the format provided
      at
      the following web address: https://contractormanpower.army.pentagon.mil.
      The
      contractor shall include the following:

     

    
      	 	(a)	Contracting Office, Contracting Officer, Contracting
              Officer’s Technical Representative


      	 	(b)	Contract number, including task and delivery order
              number


      	 	(c)	Beginning and ending dates covered by reporting
              period


      	 	(d)	Contractor name, address, phone number, e-mail address,
              identity of contractor employee entering data


      	 	(e)	Estimated direct labor hours (including
              subcontractors)


      	 	(f)	Estimated direct labor hours paid this reporting
              period
              (including subcontractors)


      	 	(g)	Total payments (including
              subcontractors)


      	 	
              (h)

            	
              Predominant
                Federal Service Code (FSC) reflecting services provided by contractor
                (and
                separate predominant FSC fore each sub-contractor if
                different)

            


      	 	(i)	Estimated data collection cost


      	 	(j)	Organizational title associated with the Unique
              Identification Code (UIC W91B94) for the Army Requiring
              Activity.


      	 	(k)	Locations where contractor and subcontractors perform
              the
              work (specified by zip code in the United States and nearest city,
              country, when in an overseas location, using standardized nomenclature
              provided on the website.


      	 	(l)	Presence of deployment or contingency contract
              language


      	 	(m)	Number of contractor and subcontractor employees
              deployed
              in theater this reporting period (by
              country).


    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 6
      of 15

    


    C.3.4.2.4
      The contractor shall also provide the estimated total cost (if any) incurred
      to
      comply with this reporting requirement. The reporting period shall be the period
      of performance not to exceed 12 months ending 30 September of each government
      fiscal year and must be reported by 3 October of each calendar year.


    


    C.3.4.2.5
      The contractor may use a direct XML data transfer to the database server or
      fill
      in the fields on the website. The XML direct transfer is a format for
      transferring files from a contractor’s system to the secure web site without the
      need for separate data entries fore each required data element at the web site.
      The specific formats for the XML direct transfer may be downloaded from the
      web
      site.

    


    Section
      D
      - Packaging and Marking

    


    SECTION
      D- PACKAGING & MARKING

    D.1.
      Hardware. All items to be delivered by the Contractor under this contract shall
      be packed and packaged in accordance with good commercial practices and in
      such
      a manner that will afford protection against corrosion, deterioration and
      physical damage for safe delivery to destination.

    


    D.2.
      Data. All data to be delivered by the Contractor under this contract shall
      be
      transmitted electronically.

     

    Section
      E
      - Inspection and Acceptance

    


    E.1
      INSPECTION AND ACCEPTANCE

    E.1.1.
      Hardware: Inspection and acceptance of all items delivered by the Contractor
      under this contract shall be at destination by the Contracting Officer’s
      Representative (COR).

    


    E.1.2.
      Data: Inspection and acceptance of data items will be performed by the first
      addressee identified in Block 14 of the Contract Data Requirements List, DD
      Form
      1423, found as an attachment to this contract.

    


    CLAUSES
      INCORPORATED BY REFERENCE

     

    
      	52.246.8	Inspection of Research And Development
              Cost
              Reimbursement	MAY 2001
	252.246-7000	Material Inspection And Receiving
              Report	MAR 2003


    

      

    INSPECTION
      AND ACCEPTANCE TERMS

    


    Supplies/services
      will be inspected/accepted at:

    


    
      	
              CLIN
                

            	
              INSPECT
                AT 

            	
              INSPECT
                BY 

            	
              ACCEPT
                AT 

            	
              ACCEPT
                BY 

            
	
              0001
                

            	
              N/A
                

            	
              N/A
                

            	
              N/A
                

            	
              Government
                

            


    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    
Page 7of
      15

     

    Section
      F
      - Deliveries or Performance

    


    PERIOD
      OF PERFORMANCE

    F.1.
      TOTAL PERIOD OF PERFORMANCE

    


    All
      work
      under this contract, including delivery or an approved final report shall be
      completed within 360 calendar days from the effective date of this
      contract.

    


    F.2.
      DELIVERY INFORMATION

    


    F.2.1.
      Data to be delivered. The Contractor shall deliver all data in accordance with
      the DD Form 1423, Contract Data Requirements List, found as an attachment to
      this contract.

    


    F.2.2.
      Hardware to be delivered. The Contractor shall deliver all hardware/prototypes
      within 360 calendar days from the effective date of this contract.

    


    F.2.3.
      The Contractor shall deliver all hardware/prototypes F.O.B. Destination to:
      

    


    U.S.
      Army
      Medical Research Institute of Infectious Disease (USAMRIID)

    Systems
      Development Branch

    Diagnostics
      Systems Division

    Building
      1425, Room RLl-201

    ATTN:
      Dr.
      David Norwood

    Fort
      Detrick, MD 21701-5011

    Phone:
      301-619-4721

    


    CLAUSES
      INCORPORATED BY REFERENCE

    


    52.242-15
      Alt I  Stop
      Work
      Order (Aug 1989) - Alternate I   APR
      1984

     

    
 

    DELIVERY
      INFORMATION

    


    
      	
              CLIN
                

            	
              DELIVERY
                DATE 

            	
              QUANTITY
                

            	
              SHIP
                TO ADDRESS 

            	
              UIC
                

            
	
               

            	
               

            	
               

            	
               

            	
               

            
	
              0001
                

            	
              15-JUN-2008
                

            	
               

            	
              U.S.
                ARMY MED RES INST INFECT DISEASE

              DAVID
                NORWOOD

              SYSTEMS
                DEVELOPMENT BRANCH, DIAGNOSTICS

              SYSTEMS
                DIVISION, BLDG 1425,RM RL-201

              FORT
                DETRICK MD 21701-5011

              301-619-4721

              FOB:
                Destination 

            	
              W81X0H
                

            


    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 8
      of 15

     

    Section
      G
      - Contract Administration Data

    


    G.1.
      SUBMISSION OF INVOICES

    Public
      vouchers (including cost and fee) request for payment shall be submitted
      electronically via the Wide Area Workflow (WAWF) to the Payment Office. An
      electronic and/or hard copy of the voucher shall be submitted to the Procuring
      Contracting Officer (PCO) as identified below. An electronic and/or hard copy,
      as determined by the Administrative Contracting Officer (ACO), shall be provided
      to the Contract Administration Office

    


    Cognizant
      Government Audit Agency:

    


    Branch
      Manager

    Defense
      Contract Audit Agency (DCAA)

    Seattle
      Branch Office

    14240
      Interurban Avenue, South, Suite 156

    Seattle,
      WA 98168

    


    Procuring
      Contracting Office:

    


    U.S.
      Army
      RDECOM Acquisition Center

    Edgewood
      Contracting Division

    AMSRD-ACC-E/Paulette
      Lato, Bldg. E4455

    E5179
      Hoadley Road

    APG
      (EA),
      MD 21010-5424

    


    Administrative
      Contracting Office:

    


    Commander

    Defense
      Contract Management Agency (DCMA) Twin Cities

    B.H.
      Whipple Federal Bldg, Room 1150, 1

    Fort
      Snelling, MN 55111-4007

    


    G.2.
      The
      Procuring Office point of contact for this action is:

    


    Paulette
      Lato

    Contract
      Specialist

    Tel:
      410-436-0667

    Fax:
      410-306-3719

    e-mail:
      paulette.lato@us.army.mil

    


    G.3.
      The
      Contracting Officer’s Representative (COR) for this action is:

    


    Roy
      G.
      Thompson

    U.S.
      Army
      RDECOM

    ATTN:
      AMSRD-ECB-RT-BM

    Building
      E3831

    Aberdeen
      Proving Ground, MD 21010

    Tel:
      410-436-5699

    Fax:
      410-436-6536

    e-mail:
      roy.thompson@us.army.mil

    


    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    


    Page 9
      of 15


    


    ACCOUNTING
      AND APPROPRIATION DATA

    


    
      	
              AA:
                2162040000066N6N6662262255200255Y9CER35W91B94703701566RQVX2S19130
                

            
	
              AMOUNT:
                $2,212,517.00 

            
	
              CIN
                000000000000000000000000000000: $2,212,517.00


            


    

    


    Section
      H
      - Special Contract Requirements

    


    H.1. 52.0000-4048
      GOVERNMENT - CONTRACTOR RELATIONSHIPS

    


    
      	(a)  	
              The
                Government and the Contractor understand and agree that the support
                services to be delivered under this contract by the Contractor are
                nonpersonal services and the parties recognize and agree that no
                employer-employee relationships exist or will exist under the contract
                between the Government and the Contractor and/or between the Government
                and the Contractor’s employees. It is, therefore, in the best interest of
                the Government to afford the parties a full and complete understanding
                of
                their respective obligation.

            


    

    


    
      	(b)  	
              Contractor
                personnel under this contract shall
                not:

            


    

    
      	(1)  	
              Be
                placed in a position where they are appointed or employed b y a Federal
                Officer, or are under the supervision, direction, or evaluation of
                a
                Federal Officer, military or
                civilian.

            


    

    
      	(2)  	
              Be
                placed in a Government staff or policy-making
                position.

            


    

    
      	(3)  	
              Be
                placed in a position of command, supervision, direction, or evaluation
                over DA military or civilian personnel, or personnel of other contractors
                or become a part of a Government
                organization.

            


    

    


    
      	(c)  	
              Employee
                Relationship:

            


    

    
      	(1)  	
              The
                services to be performed under this contract do not require the Contractor
                or its employees to exercise personal judgment and discretion on
                behalf of
                the Contractor.

            


    

    
      	(2)  	
              Rules,
                regulations, directions and requirements, which are issued by Government
                command authorities under their responsibility for good order,
                administration and security are applicable to all personnel who enter
                a
                Government installation. This is not to be construed or interpreted
                to
                establish any degree of Government control, which is inconsistent
                with a
                nonpersonal services contract.

            


    

    
      	(3)  	
              The
                Contractor will not be paid for performance of personal services.
                Therefore, in the event the Contractor (or its employee) is directed
                by
                any Government employee to perform tasks that the Contractor believes
                are
                personal services the Contractor should take no action until it has
                contacted the Procuring Contracting Officer to determine the appropriate
                course of action.

            


    

    


    H.2. 52.0000-4160 GUIDANCE
      ON DOCUMENTATION OF DATA REQUIREMENTS

    


    The
      following information is furnished to provide guidance with respect to the
      abbreviations and codes utilized in various blocks of DD Form 1423, Contract
      Data Requirements List.

    


    Block
      7,
      DD Form 250 Requirement. This block designates the location (source or
      destination) for performance of Government inspection and acceptance. The
      applicable codes for inspection and acceptance are cited below. The Government
      activity to perform the destination acceptance task is entered in Block 14
      as
      the first addressee.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 10
      of 15

    
Code
      Inspection Acceptance


    
      	
              SS+Source
                (DD Form 250

              DD
                De4stination (DD Form 250)

              SD+Source
                (DD Form 250)

              DS
                Destination (DD Form 250)

              ++LT
                Letter of Transmittal Only

              NO
                No inspection or acceptance required

            	
              +Source (DD Form 2500

              Destination (DD Form 250)

              Destination (DD Form 250)

              +Source (DD Form
                250)

            


    

    XX
      Inspection/acceptance requirements specified elsewhere in the
      contract

    +Source
      indicated Contractor’s facility

    ++Use
      of
      these symbols is not authorized for engineering data such as drawings or
      specifications

    


    Block
      8,
      Approval Code. Items or critical data requiring specific advanced written
      approval, such as test plans, are identified by an “A” in this field. Most of
      these data require submission of a preliminary draft prior to publication of
      a
      final document. When advanced approval is not required, this field is
      blank.

    


    Block
      10,
      Frequency. The codes used in this block are cited below:

    


    DAILY
      =
      Daily

    BI-MO
      =
      Each two months

    OTIME
      =
      One time

    WEEKLY
      =
      Weekly

    QRTRLY
      =
      Quarterly

    ONE/R
      =
      One time and revision

    BI-WE
      =
      Each two weeks

    ANNLY
      =
      Annually

    R/ASR
      =
      Revision as required

    MTHLY
      =
      Monthly

    SEMIA
      =
      Each six months

    DFDEL
      =
      Deferred Delivery

    ASREQ
      =
      As required

    2TIME
      =
      Two separate

    CNE/P
      =
      One time preliminary (See Notes A/B Submittals draft)

    CHG
      P AS
      REQ = Change pages as required

    


    Note
      A:
      Block 13 is used for further explanation

    Note
      B:
      When data is of a recurring type, it will be submitted at end of reporting
      period established in field unless otherwise indicated in Data Preparation
      Instructions or in Blocks 12 or 13 of DD Form 1423.

    


    Block
      11,
      As of Date (AOD). When data is submitted only once, this block indicates the
      number of days the data is to be submitted prior to the end of the reporting
      period; e.g., “15” would place the AOD for this report at 15 calendar days
      before the end of each month, quarter, or year, depending on the frequency
      established in Block 10; “0” place the AOD at the end of the month, quarter, or
      year. Further guidance is shown in Block 13 or 16 as required.

    


    Block
      12,
      Data of First Submission. This block indicated the inniti9al data submission
      date (Year/Month/Day). When data has already been submitted and will be
      resubmitted, the data of the next submission is entered. When the contract
      starts, the date has not been established, this block indicates the number
      of
      calendar days after the contract start date that the data is due; e.g., 30
      DAC.
      Further information, if required, is contained in Block 13. Classified dates
      are
      not cited in this form. “DFDEL” indicates deferred delivery.

    


    Block
      13,
      Date of Subsequent Submission/Event Identification. When data is submitted
      more
      than once, the date(s) of subsequent submission(s) is indicated in this block.
      When submission of data is based on the initiation of a specific event ore
      milestone, this information is cited in this block (when such information
      classifies the form, this block is left blank). Example: “NLT 15 calendar days
      before start of production;” “45 calendar days before first article,”
etc.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 11
      of 15

     

    Block
      14,
      Distribution and Addresses. Addresses and number of copies
      (regular/reproducible) to be forwarded to each addressee is cited in this block;
      e.g. SCBRD-ORD-E 0/1/0. Addresses are indicated by office symbol (i.e.,
      STEAA-AP-EP), contractor initials, DoD Handbook H-4 codes, and Command initials.
      A list explaining these symbols is attached to the form. When reproducible
      copies are required (second number), the type of copies required will be cited
      in this block or Block 16.

    


    NOTE:
      Unless otherwise cited in Block 10, entries in Blocks 3 through 9 on DD Forms
      1664, Data Item Description, are for information purposes only and are not
      contractually binding.

    


    H.3. LIMITATION
      OF COSTS

    


    In
      accordance with the clause FAR 52.232-20 Limitation of Cost April 1984,
      incorporated into this contract, the notice required thereby shall be provided
      to the designated Procuring Contracting Officer by CERTIFIED MAIL return receipt
      requested. Failure to comply with the above notice requirement imposes the
      risk
      of continued performance on the contract without reimbursement to the contractor
      for cost incurred over and above the estimated cost or allotted amount stated
      in
      the contract.

    


    H.4. 52.0000-4147 NOTICE
      OF
      INCORPORATION OF CERTIFICATIONS The certifications are incorporated in and
      form
      a part of the resultant contract as though furnished in full test
      therewith.

    


    H.5. GOVERNMENT
      FURNISHED PROPERTY

    


    The
      following antibodies and antigens will be provided through the USAMRIID CRADA,
      dated November 23, 2003, for the use by the Contractor under this contract.
      (A
      copy of the CRADA is available from the COR upon request).

     

    
      	ITEM	DESCRIPTION	QTY	DOLLAR VALUE	DELIVERY DATE
	 	 	 	 	 
	1	
              Staphylococcal

              Enterotoxin
                B (SEB)

            	1	NSP**	30 CDAC
	 	 	 	 	 
	2	
              Venezuelan

              Encephalitis

              (VEE)

            	1	NSP**	30 CDAC
	 	 	 	 	 
	3	
              Y.
                pestis

              (plague)

            	1	NSP**	30 CDAC
	 	 	 	 	 
	4	
              B. anthraces

              (anthrax)

            	1	NSP**	30
              CDAC


    

          

    *CDAC-Calendar
      Days after Contract Award

    **NSP
      -
      Not separately priced

    


    H.5.1.
      Pursuant to the Government Property Clause in Section I of this contract, the
      Government will furnish F.O.B., Contractor’s place of performance, the
      Government-owned property listed in paragraph H.5.1 for use in the performance
      of this contract.

    


    H.5.2.
      The property shall be delivered in accordance with the schedule set forth in
      paragraph H.5.1.

    


    H.6.
      TECHNICAL DATA RIGHTS

    


    The
      Government desires unlimited rights to all data.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    
Page 12
      of 15

     

    H.7.
      Hazards Information: This procurement request does not require the contractor
      to
      handle chemical agents. As far as can be determined, known or suspect
      carcinogens are not involved. This effort will require the contractor to perform
      microbiological and/or biomedical work.

    


    H.8.
      This
      procurement request does not require the contractor to use animals, human
      volunteers or conduct DNA recombinant work.

    


    Section
      I
      - Contract Clauses

    


    CLAUSES
      INCORPORATED BY REFERENCE

     

    
      	
              52.202-1
                

            	
              Definitions
                

            	
              JUL
                2004 

            	
               

            
	
              52.203-3
                

            	
              Gratuities
                

            	
              APR
                1984 

            	
               

            
	
              52.203-5
                

            	
              Covenant
                Against Contingent Fees 

            	
              APR
                1984 

            	
               

            
	
              52.203-6
                

            	
              Restrictions
                On Subcontractor Sales To The Government 

            	
              SEP
                2006 

            	
               

            
	
              52.203-7
                

            	
              Anti-Kickback
                Procedures 

            	
              JUL
                1995 

            	
               

            
	
              52.203-8
                

            	
              Cancellation,
                Rescission, and Recovery of Funds for Illegal or Improper Activity
                

            	
              JAN
                1997 

            	
               

            
	
              52.203-10
                

            	
              Price
                Or Fee Adjustment For Illegal Or Improper Activity 

            	
              JAN
                1997 

            	
               

            
	
              52.203-12
                

            	
              Limitation
                On Payments To Influence Certain Federal Transactions 

            	
              SEP
                2005 

            	
               

            
	
              52.204-4
                

            	
              Printed
                or Copied Double-Sided on Recycled Paper 

            	
              AUG
                2000 

            	
               

            
	
              52.209-6
                

            	
              Protecting
                the Government's Interest When Subcontracting With Contractors Debarred,
                Suspended, or Proposed for Debarment 

            	
              SEP
                2006 

            	
               

            
	
              52.211-15
                

            	
              Defense
                Priority And Allocation Requirements 

            	
              SEP
                1990 

            	
               

            
	
              52.215-2
                

            	
              Audit
                and Records--Negotiation 

            	
              JUN
                1999 

            	
               

            
	
              52.215-8
                

            	
              Order
                of Precedence--Uniform Contract Format 

            	
              OCT
                1997 

            	
               

            
	
              52.215-14
                Alt I 

            	
              Integrity
                of Unit Prices (Oct 1997) - Alternate I 

            	
              OCT
                1997 

            	
               

            
	
              52.215-15
                

            	
              Pension
                Adjustments and Asset Reversions 

            	
              OCT
                2004 

            	
               

            
	
              52.215-17
                

            	
              Waiver
                of Facilities Capital Cost of Money 

            	
              OCT
                1997 

            	
               

            
	
              52.215-18
                

            	
              Reversion
                or Adjustment of Plans for Postretirement Benefits (PRB) Other than
                Pensions 

            	
              JUL
                2005 

            	
               

            
	
              52.215-19
                

            	
              Notification
                of Ownership Changes 

            	
              OCT
                1997 

            	
               

            
	
              52.216-7
                

            	
              Allowable
                Cost And Payment 

            	
              DEC
                2002 

            	
               

            
	
              52.216-8
                

            	
              Fixed
                Fee 

            	
              MAR
                1997 

            	
               

            
	
              52.219-8
                

            	
              Utilization
                of Small Business Concerns 

            	
              MAY
                2004 

            	
               

            
	
              52.222-2
                

            	
              Payment
                For Overtime Premiums 

            	
              JUL
                1990 

            	
               

            
	
              52.222-3
                

            	
              Convict
                Labor 

            	
              JUN
                2003 

            	
               

            
	
              52.222-21
                

            	
              Prohibition
                Of Segregated Facilities 

            	
              FEB
                1999 

            	
               

            
	
              52.222-26
                

            	
              Equal
                Opportunity 

            	
              MAR
                2007 

            	
               

            
	
              52.222-35
                

            	
              Equal
                Opportunity For Special Disabled Veterans, Veterans of the Vietnam
                Era,
                and Other Eligible Veterans 

            	
              SEP
                2006 

            	
               

            
	
              52.222-36
                

            	
              Affirmative
                Action For Workers With Disabilities 

            	
              JUN
                1998 

            	
               

            
	
              52.222-37
                

            	
              Employment
                Reports On Special Disabled Veterans, Veterans Of The Vietnam Era,
                and
                Other Eligible Veterans 

            	
              SEP
                2006 

            	
               

            
	
              52.223-6
                

            	
              Drug-Free
                Workplace 

            	
              MAY
                2001 

            	
               

            
	
              52.223-14
                

            	
              Toxic
                Chemical Release Reporting 

            	
              AUG
                2003 

            	
               

            
	
              52.225-13
                

            	
              Restrictions
                on Certain Foreign Purchases 

            	
              FEB
                2006 

            	
               

            
	
              52.227-1
                Alt I 

            	
              Authorization
                And Consent (Jul 1995) - Alternate I 

            	
              APR
                1984 

            	
               

            
	
              52.227-2
                

            	
              Notice
                And Assistance Regarding Patent And Copyright Infringement


            	
              AUG
                1996 

            	
               

            


    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 13
      of 15

     

    
      	
              52.227-11
                

            	
              Patent
                Rights--Retention By The Contractor (Short Form) 

            	
              JUN
                1997 

            	
               

            
	
              52.228-7
                

            	
              Insurance--Liability
                To Third Persons 

            	
              MAR
                1996 

            	
               

            
	
              52.232-9
                

            	
              Limitation
                On Withholding Of Payments 

            	
              APR
                1984 

            	
               

            
	
              52.232-17
                

            	
              Interest
                

            	
              JUN
                1996 

            	
               

            
	
              52.232-20
                

            	
              Limitation
                Of Cost 

            	
              APR
                1984 

            	
               

            
	
              52.232-23
                Alt I 

            	
              Assignment
                of Claims (Jan 1986) - Alternate I 

            	
              APR
                1984 

            	
               

            
	
              52.232-25
                Alt I 

            	
              Prompt
                Payment (Oct 2003) Alternate I 

            	
              FEB
                2002 

            	
               

            
	
              52.232-33
                

            	
              Payment
                by Electronic Funds Transfer--Central Contractor Registration
                

            	
              OCT
                2003 

            	
               

            
	
              52.233-1
                

            	
              Disputes
                

            	
              JUL
                2002 

            	
               

            
	
              52.233-3
                Alt I 

            	
              Protest
                After Award (Aug 1996) - Alternate I 

            	
              JUN
                1985 

            	
               

            
	
              52.242-1
                

            	
              Notice
                of Intent to Disallow Costs 

            	
              APR
                1984 

            	
               

            
	
              52.242-3
                

            	
              Penalties
                for Unallowable Costs 

            	
              MAY
                2001 

            	
               

            
	
              52.242-4
                

            	
              Certification
                of Final Indirect Costs 

            	
              JAN
                1997 

            	
               

            
	
              52.242-13
                

            	
              Bankruptcy
                

            	
              JUL
                1995 

            	
               

            
	
              52.243-2
                Alt V 

            	
              Changes--Cost-Reimbursement
                (Aug 1987) - Alternate V 

            	
              APR
                1984 

            	
               

            
	
              52.244-2
                Alt I 

            	
              Subcontracts
                (Aug 1998) - Alternate I 

            	
              JAN
                2006 

            	
               

            
	
              52.244-5
                

            	
              Competition
                In Subcontracting 

            	
              DEC
                1996 

            	
               

            
	
              52.244-6
                

            	
              Subcontracts
                for Commercial Items 

            	
              MAR
                2007 

            	
               

            
	
              52.245-5
                

            	
              Government
                Property (Cost-Reimbursement Time-And-Materials, Or Labor Hour Contracts)
                

            	
              MAY
                2004 

            	
               

            
	
              52.246-25
                

            	
              Limitation
                Of Liability--Services 

            	
              FEB
                1997 

            	
               

            
	
              52.249-6
                

            	
              Termination
                (Cost Reimbursement) 

            	
              MAY
                2004 

            	
               

            
	
              52.249-14
                

            	
              Excusable
                Delays 

            	
              APR
                1984 

            	
               

            
	
              52.253-1
                

            	
              Computer
                Generated Forms 

            	
              JAN
                1991 

            	
               

            
	
              252.201-7000
                

            	
              Contracting
                Officer's Representative 

            	
              DEC
                1991 

            	
               

            
	
              252.203-7001
                

            	
              Prohibition
                On Persons Convicted of Fraud or Other Defense-Contract-Related Felonies
                

            	
              DEC
                2004 

            	
               

            
	
              252.204-7000
                

            	
              Disclosure
                Of Information 

            	
              DEC
                1991 

            	
               

            
	
              252.204-7003
                

            	
              Control
                Of Government Personnel Work Product 

            	
              APR
                1992 

            	
               

            
	
              252.204-7004
                Alt A 

            	
              Central
                Contractor Registration (52.204-7) Alternate A 

            	
              NOV
                2003 

            	
               

            
	
              252.205-7000
                

            	
              Provision
                Of Information To Cooperative Agreement Holders 

            	
              DEC
                1991 

            	
               

            
	
              252.209-7004
                

            	
              Subcontracting
                With Firms That Are Owned or Controlled By The Government of a Terrorist
                Country 

            	
              DEC
                2006 

            	
               

            
	
              252.223-7004
                

            	
              Drug
                Free Work Force 

            	
              SEP
                1988 

            	
               

            
	
              252.225-7001
                

            	
              Buy
                American Act And Balance Of Payments Program 

            	
              JUN
                2005 

            	
               

            
	
              252.225-7002
                

            	
              Qualifying
                Country Sources As Subcontractors 

            	
              APR
                2003 

            	
               

            
	
              252.225-7012
                

            	
              Preference
                For Certain Domestic Commodities 

            	
              JAN
                2007 

            	
               

            
	
              252.225-7031
                

            	
              Secondary
                Arab Boycott Of Israel 

            	
              JUN
                2005 

            	
               

            
	
              252.226-7001
                

            	
              Utilization
                of Indian Organizations and Indian-Owned Economic Enterprises, and
                Native
                Hawaiian Small Business Concerns 

            	
              SEP
                2004 

            	
               

            
	
              252.227-7013
                

            	
              Rights
                in Technical Data--Noncommercial Items 

            	
              NOV
                1995 

            	
               

            
	
              252.227-7014
                

            	
              Rights
                in Noncommercial Computer Software and Noncommercial Computer Software
                Documentation 

            	
              JUN
                1995 

            	
               

            
	
              252.227-7016
                

            	
              Rights
                in Bid or Proposal Information 

            	
              JUN
                1995 

            	
               

            
	
              252.227-7019
                

            	
              Validation
                of Asserted Restrictions--Computer Software 

            	
              JUN
                1995 

            	
               

            
	
              252.227-7027
                

            	
              Deferred
                Ordering Of Technical Data Or Computer Software 

            	
              APR
                1988 

            	
               

            
	
              252.227-7028
                

            	
              Technical
                Data or Computer Software Previously Delivered to the Government
                

            	
              JUN
                1995 

            	
               

            
	
              252.227-7030
                

            	
              Technical
                Data--Withholding Of Payment 

            	
              MAR
                2000 

            	
               

            
	
              252.227-7037
                

            	
              Validation
                of Restrictive Markings on Technical Data 

            	
              SEP
                1999 

            	
               

            
	
              252.227-7039
                

            	
              Patents--Reporting
                Of Subject Inventions 

            	
              APR
                1990 

            	
               

            
	
              252.231-7000
                

            	
              Supplemental
                Cost Principles 

            	
              DEC
                1991 

            	
               

            


    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    Page 14
      of 15

     

    
      	
              252.232-7003
                

            	
              Electronic
                Submission of Payment Requests 

            	
              MAR
                2007 

            	
               

            
	
              252.235-7010
                

            	
              Acknowledgment
                of Support and Disclaimer 

            	
              MAY
                1995 

            	
               

            
	
              252.235-7011
                

            	
              Final
                Scientific or Technical Report 

            	
              NOV
                2004 

            	
               

            
	
              252.242-7002
                

            	
              Earned
                Value Management System 

            	
              MAR
                2005 

            	
               

            
	
              252.244-7000
                

            	
              Subcontracts
                for Commercial Items and Commercial Components (DoD Contracts)
                

            	
              JAN
                2007 

            	
               

            
	
              252.245-7001
                

            	
              Reports
                Of Government Property 

            	
              MAY
                1994 

            	
               

            
	
              252.247-7023
                

            	
              Transportation
                of Supplies by Sea 

            	
              MAY
                2002 

            	
               

            
	
              252.247-7024
                

            	
              Notification
                Of Transportation Of Supplies By Sea 

            	
              MAR
                2000 

            	
               

            


    

     

    CLAUSES
      INCORPORATED BY FULL TEXT

    


    52.252-2
      CLAUSES INCORPORATED BY REFERENCE (FEB 1998) 

    


    This
      contract incorporates one or more clauses by reference, with the same force
      and
      effect as if they were given in full text. Upon request, the Contracting Officer
      will make their full text available. Also, the full text of a clause may be
      accessed electronically at this/these address(es):

    


    http://www.arnet.gov/far/

    http://www.acq.osd.mil/dp/dars/

    http://farsite.hill.af.mil

    http://web1.deskbook.osd.mil/htmlfiles/rlcats.asp

    


    (End
      of
      clause)

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    
Page 15
      of 15

     

    Section
      J
      - List of Documents, Exhibits and Other Attachments

    


    


    
      	
               CONTRACT
                DATA REQUIREMENTS LIST

              (2
                Data Items)

            	
              FORM
                APPROVED

              OMB
                No. 0704-0188

            
	
              Public
                reporting burden for this collection is estimated to average 330
                hours per
                response, including the time for reviewing instructions, searching
                existing data sources, gathering and maintaining the data needed,
                and
                completing and reviewing the collection of information. Send comments
                regarding this burden estimate or any other aspect of this collection
                of
                information, including suggestions for reducing this burden, to DoD,
                Washington Headquarters Services, Directorate for Information Operations
                and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington,
                VA
                22202-4302, and to the Office of Management and Budget, Paperwork
                Reduction Project (0704-0188), Washington, DC 20503. Please DO NOT
                RETURN
                your form to either of these addresses. Send completed form to the
                Government issuing Contracting Officer for the Contract/PR No. Listed
                in
                Block E. 

            
	
              A.
                CONTRACT LINE ITEM NO.

            	
              B.
                EXHIBIT A

            	
              C.
                CATEGORY TDP_______
                TM_______ OTHER General
                Data  

            
	
              D.
                SYSTEM/ITEM ITEM BAA
                - Development of a CMOS Microarray Platform for Bio and Chemical
                Threat
                Agent Detection

            	
              E.
                CONTRACT/PR NO.

              W911SR-05-C-

            	
              F.
                CONTRACTOR 

              CombiMatrix,
                Inc.

            
	
              1.
                DATA ITEM NO.

              A001

            	
              2.
                TITLE OF DATA ITEM Contractor’s
                Progress, Status and Management Report

            	
              3.
                SUBTITLE

              Progress
                Report

            
	
              4.
                AUTHORITY (Data Acquisition Document No.)

              DI-MGMT-80227
                

            	
              5.
                CONTRACT REFERENCE

               Paragraph
                C.3.4.1.1

            	
              6.
                REQUIRING OFFICE

              AMSRD-ECB-RT-BM

            
	
              7.
                DD 250 REQ

              LT

            	
              9.
                DIST STATEMENT

              REQUIRED

              NA

            	
              10.
                FREQUENCY

              MTHLY

            	
              12.
                DATE OF FIRST SUBMISSION

              40
                CDAC

            	
              14.
                DISTRIBUTION

            
	
              a.
                Addressee

            	
              b.
                COPIES

              FINAL

            
	
              8.
                APP CODE

              NO

            	
              11.
                AS OF DATE

               

              0

            	
              13.
                DATE OF SUBSEQUENT SUBMISSION 

               

            	 	
              D

              r

              a

              f

              t

            	
              R

              e

              g

            	
              R

              e

              p

              r

              o

            
	
              16.
                REMARKS. 

              4.
                DID may be obtained at: http://assist.daps.dla.mil/quicksearch/. Paragraphs
                10.3.f, g, h, i, and l do not apply.

              12.
                CDAC: Calendar days after award of contract.

              14.
                Submit in electronic format in Microsoft Office 2000 (Word, Excel
&
                Powerpoint) or in another format approved by the Government to
                roy.thompson@us.army.mil
                (COR, AMSRD-ECB-RT-BM) and glen.mattingly@us.army.mil
                (AMSRD-ACC-E). 

              LT:
                Letter (notification) of transmittal.

              *15.
                Electronic submission.

            	
               

              AMSRD-ECB-RT-BM

            	
               

              0

            	
               

              1

            	
               

              0

            
	
               

              AMSRD-ACC-E

            	
               

              0

            	
               

              1

            	
               

              0

            
	
               

              DCMA

            	
               

              0

            	
               

              LT

            	
               

              0

            
	
               

              15.
                TOTAL

            	
               

              0

            	
               

               1*

            	
               

              0

            
	
              1.
                DATA ITEM NO.

              A002

            	
              2.
                TITLE OF DATA ITEM 

              Scientific
                and Technical Report

            	
              3.
                SUBTITLE

              Final
                Comprehensive Report

            
	
              4.
                AUTHORITY (Data Acquisition Document No.)

              DI-MISC-80711A

            	
              5.
                CONTRACT REFERENCE

               Paragraph
                C.3.4.1.2

            	
              6.
                REQUIRING OFFICE

              AMSRD-ECB-RT-BM

            
	
              7.
                DD 250 REQ

              LT

            	
              9.
                DIST STATEMENT

              REQUIRED

              B

            	
              10.
                FREQUENCY

              ONE/R

            	
              12.
                DATE OF FIRST SUBMISSION

              330
                CDAC

            	
              14.
                DISTRIBUTION

            
	
              8.
                APP CODE

              A

            	
              11.
                AS OF DATE

               

               

            	
              13.
                DATE OF SUBSEQUENT SUBMISSION 

              15
                calendar days after receipt
                of Government comments

            	
              a.
                Addressee

            	
              b.
                COPIES

              FINAL

            
	 	
              D

              r

              a

              f

              t

            	
              R

              e

              g

            	
              R

              e

              p

              r

              o

            
	
              16.
                REMARKS. 

              4.
                DID may be obtained at http://assist.daps.dla.mil/quicksearch/. 

              8.
                The Government will respond with comments or approval within 15 calendar
                days after receipt of draft report. 

              9.
                Distribution guidance is provided in DOD Dir 5230.24 (http://www.dtic.mil/whs/directives/).

              14.
                & 15. Submit via electronic mail in Microsoft Office (Word, Excel
                & Powerpoint) or in a different format if approved by the Government
                tomailto:michael.goode@sbccom.apgea.army.mil roy.thompson@us.army.mil
                (COR, AMSRD-ECB-RT-BM) and glen.mattingly@us.army.mil
                (AMSRD-ACC-E). LT: Letter (notification) of transmittal.

            	
               

              AMSRD-ECB-RT-BM

            	
               

              1

            	
               

              1

            	
               

              0

            
	
               

              AMSRD-ACC-E

            	
               

              LT

            	
               

              1

            	
               

              0

            
	
               

              DCMA

            	
               

              0

            	
               

              LT

            	
               

              0

            
	 	 	 	 
	
              15.
                TOTAL

            	
              1

            	
               1

            	
              0

            
	
              17.
                PRICE GROUP

            	
              18.
                ESTIMATED TOTAL PRICE

            
	
              G.
                PREPARED BY

              /s/
                ROY THOMPSON

            	
              H.
                DATE

              21
                March 2007

            	
              I.
                APPROVED BY

              /s/
                JACKIE A BURKE

            	
              J.
                DATE

              22
                March 2006

            


    

    DD
      FORM 1423-2, JUN 90 Previous
      editions are obsolete Page
      1