TECHNOLOGY
      LICENSE AGREEMENT

     

    BETWEEN

     

    CARDIOVASCULAR
      BIOTHERAPEUTICS, INC.

     

    AND

     

    PRODERM,
      LP

     

    Dated
      as
      of July 8, 2008

     


    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    


    TABLE
      OF
      CONTENTS

     

    
      	 	 	 	
              Page

            
	 	 	 
	
              1.

            	
              Definitions

            	
              1

            
	 	
              1.1

            	
              Definitions

            	
              1

            
	 	
              1.2

            	
              Singular
                and Plural

            	
              1

            
	 	 	 
	
              2.

            	
              Grant
                of Licenses

            	
              1

            
	 	
              2.1

            	
              Grant
                of Nonexclusive Licenses to PDLP; Right to Sublicense.

            	
              1

            
	 	
              2.2

            	
              Third
                Party Licenses to CVBT or Any of Its Affiliates

            	
              2

            
	 	
              2.3

            	
              PDLP
                Sublicenses and Licenses to CVBT.

            	
              2

            
	 	 	 
	
              3.

            	
              Representations,
                Warranties and Covenants

            	
              3

            
	 	
              3.1

            	
              Representations,
                Warranties and Covenants of CVBT

            	
              3

            
	 	
              3.2

            	
              Representations,
                Warranties and Covenants of PDLP

            	
              4

            
	 	 	 	 
	
              4.

            	
              Patents

            	 	
              4

            
	 	
              4.1

            	
              Derived
                from the Development

            	
              4

            
	 	
              4.2

            	
              Rights
                After Termination of Agreements

            	
              4

            
	 	 	 
	
              5.

            	
              Confidential
                Information

            	
              5

            
	 	 	 
	
              6.

            	
              Permitted
                Disclosures

            	
              5

            
	 	 	 
	
              7.

            	
              Disclaimer
                of Warranty; Consequential Damages

            	
              5

            
	 	
              7.1

            	
              Disclaimer
                of Warranty

            	
              5

            
	 	
              7.2

            	
              Consequential
                Damages

            	
              6

            
	 	 	 
	
              8.

            	
              Indemnification

            	
              6

            
	 	
              8.1

            	
              Indemnification
                by CVBT

            	
              6

            
	 	
              8.2

            	
              Indemnification
                by PDLP

            	
              6

            
	 	
              8.3

            	
              Defense
                of Claims

            	
              7

            
	 	 	 
	
              9.

            	
              Term
                and Termination

            	
              7

            
	 	
              9.1

            	
              Term

            	
              7

            
	 	
              9.2

            	
              Termination
                by Mutual Agreement

            	
              7

            
	 	
              9.3

            	
              Termination
                of Development

            	
              7

            
	 	
              9.4

            	
              Termination
                by CVBT or PDLP for Breach

            	
              7

            
	 	
              9.5

            	
              Termination
                After Full Payment

            	
              7

            
	 	
              9.6

            	
              Effect
                of Termination

            	
              7

            
	 	
              9.7

            	
              Continuing
                Obligation to Make Payments

            	
              8

            
	 	 	 
	
              10.

            	
              Miscellaneous

            	
              8

            
	 	
              10.1

            	
              No
                Implied Waivers; Rights Cumulative

            	
              8

            
	 	
              10.2

            	
              Force
                Majeure

            	
              8

            
	 	
              10.3

            	
              Relationship
                of the Parties

            	
              8

            
	 	
              10.4

            	
              Notices

            	
              8

            
	 	
              10.5

            	
              Successors
                and Assigns

            	
              9

            


    

     

    
      
        
        

      

      
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              10.6

            	
              Amendments

            	
              9

            
	 	
              10.7

            	
              Governing
                Law

            	
              10

            
	 	
              10.8

            	
              Severability

            	
              10

            
	 	
              10.9

            	
              Trading
                Limitations

            	
              10

            
	 	
              10.10

            	
              Counterparts

            	
              10

            
	 	
              10.11

            	
              Entire
                Agreement

            	
              10

            


    

     

    
      
        
        

      

      
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    TECHNOLOGY
      LICENSE AGREEMENT

     

    This
      Technology License Agreement (the “Agreement”) is made as of July 8, 2008, by
      and between CardioVascular BioTherapeutics, Inc., a Delaware corporation
      (“CVBT”) and ProDerm, LP, a Nevada limited partnership (“PDLP”).

     

    RECITALS

     

    A. CVBT
      and
      PDLP are parties to the Development Agreement (all capitalized terms shall
      have
      the respective meanings set forth in Section 1 hereof).

     

    B. CVBT
      is
      the owner of the Wound Healing IP and certain intellectual property rights
      relating thereto.

     

    C. Pursuant
      to the Development Agreement, PDLP has engaged CVBT to employ the Wound Healing
      IP in conducting the Development.

     

    E. In
      the
      Development process, CVBT may develop additional inventions, processes, data,
      know-how, or enhancements of, or relating to, the Wound Healing IP (the “Program
      IP”).

     

    F. CVBT
      desires to acquire, and PDLP is willing to grant to CVBT, an exclusive worldwide
      license or sublicense to exploit the Program IP as it deems
      appropriate.

     

    NOW,
      THEREFORE, in consideration of the mutual covenants set forth herein and for
      other good and valuable consideration, the receipt and sufficiency of which
      are
      hereby acknowledged, and in order to induce CVBT to enter into the Agreements,
      CVBT and PDLP hereby agree as follows:

     

    1. Definitions.

     

    1.1 Definitions.
      All
      capitalized terms used herein and not otherwise defined shall have the
      respective meanings, to the extent such terms are used herein, set forth in
      Schedule 1.1 attached hereto, which is incorporated by this reference as though
      fully set forth herein.

     

    1.2 Singular
      and Plural.
      Singular and plural forms, as the case may be, of terms defined herein shall
      have correlative meanings.

     

    2. Grant
      of Licenses.

     

    2.1 Grant
      of Nonexclusive Licenses to PDLP; Right to Sublicense.

     

    2.1.1 CVBT
      Grant.
      Subject
      to the terms and conditions of this Agreement, CVBT hereby grants to PDLP a
      nonexclusive perpetual, worldwide right and license, terminable only as set
      forth herein, to employ CVBT’s Wound Healing IP for purposes of the Development.
      PDLP understands and acknowledges that CVBT may grant similar licenses to other
      research and development partnerships for purposes of additional development
      of
      the Wound Healing IP or the Program IP.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    2.2 Third
      Party Licenses to CVBT or Any of Its Affiliates.
      With
      respect to the rights of third parties that may be obtained by CVBT after the
      date hereof, and which are necessary or useful to the Development under the
      Development Agreement, CVBT shall use commercially reasonable efforts to secure
      such rights and the right to sublicense such rights to PDLP and shall sublicense
      such rights to PDLP whenever possible; provided that PDLP shall not be obligated
      to accept any grant of rights or assume any obligations hereunder without its
      prior written consent. If PDLP desires to obtain any such rights licensed to
      CVBT or any of its Affiliates pursuant to an agreement with any Person other
      than PDLP (a “Third Party Agreement”), the existence of which CVBT shall
      promptly inform PDLP, PDLP and CVBT agree to negotiate in good faith regarding
      the allocation between CVBT or any of its Affiliates and PDLP of the royalty,
      license fee, milestone fee or other payments payable to the third party and
      the
      assumption of any obligations applicable to such license, if any. PDLP shall
      bear the cost of obtaining any such rights and shall assume such obligations
      only in proportion to its and its sublicensees’ (other than CVBT’s and/or any of
      its Affiliates) use of such rights. Any sublicense granted to PDLP hereunder
      shall be limited to the rights that CVBT and/or any of its Affiliates has a
      right to grant under any such Third Party Agreement and to any obligations
      under
      any such Third Party Agreement, and to any obligations assumed by CVBT and/or
      any of its Affiliates in consideration of the grant or assignment of such rights
      to CVBT which are to be sublicensed to PDLP. No party shall take any action,
      or
      fail to take any action within its control, that would constitute or give rise
      to a breach or other violation by CVBT or any of its Affiliates of any such
      Third Party Agreement. The parties agree that no future licensing fees are
      required to be paid by PDLP during the term of this Agreement as consideration
      for the licenses and sublicenses granted to PDLP hereunder, except as set forth
      in this Section 2.2.

     

    2.3 PDLP
      Sublicenses and Licenses to CVBT.

     

    2.3.1 Development
      License.
      PDLP
      hereby grants CVBT an exclusive, even as to PDLP and all other Persons,
      royalty-free license to employ and engage in any and all uses of the Wound
      Healing IP to conduct Development, subject to the terms and conditions of and
      to
      the extent necessary to perform its obligations under the Development Agreement.
      The rights granted under this Section 2.3.1 may be further sublicensed by CVBT
      only to its Affiliates or as permitted under of the Development Agreement (and,
      in such a case, solely to the extent necessary to perform any subcontracting
      services thereunder) or to other research and development partnerships for
      purposes of additional development of the Wound Healing IP or the Program
      IP.

     

    2.3.2 Commercialization
      License.
      PDLP
      hereby grants CVBT an exclusive, even as to PDLP and all other Persons,
      worldwide license to use the Program IP to further develop the Wound Healing
      IP
      or make, have made, use or sell products based on the Wound Healing IP and/or
      Program IP subject to the terms and conditions of and to the extent necessary
      to
      perform its obligations under the Development Agreement. The rights granted
      under this Section 2.3.2 may be further sublicensed by CVBT only to its
      Affiliates or, to the extent necessary to perform any subcontracting services
      under the Development Agreement, or to other research and development
      partnerships for purposes of additional development of the Wound Healing IP
      or
      the Program IP. Payments due to PDLP hereunder are as specified in Section
      5 of
      the Development Agreement.

     

    
      
        
        

      

      
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    2.3.3 Other
      Licenses.
      The
      foregoing licenses are granted in addition to, and not in substitution for,
      any
      other license granted to CVBT.

     

    3. Representations,
      Warranties and Covenants.

     

    3.1 Representations,
      Warranties and Covenants of CVBT.
      CVBT
      represents, warrants and covenants to PDLP as follows:

     

    3.1.1 Organization
      of CVBT.
      CVBT is
      a corporation duly organized, validly existing and in good standing under the
      laws of the State of Delaware with full corporate power and authority adequate
      for executing and delivering and performing its obligations under this
      Agreement.

     

    3.1.2 Authorization.
      The
      execution, delivery and performance of this Agreement have been duly authorized
      by all necessary corporate action on the part of CVBT and this Agreement shall
      constitute a legal, valid and binding obligation of CVBT, enforceable against
      CVBT in accordance with its terms, subject to laws of general application
      relating to bankruptcy, insolvency and the relief of debtors.

     

    3.1.3 Other
      Agreements.
      CVBT
      shall not enter into any agreement, make any commitment, take any action or
      fail
      to take any action that would contravene any material provision of, or
      materially derogate or restrict any of the rights and licenses granted or
      assigned to PDLP under, this Agreement; provided however, CVBT may enter into
      other contracts with other research and development partnerships for the purpose
      of further development of the Wound Healing IP or the Program IP. CVBT agrees
      to
      abide and be bound by the terms of any license agreement to which it is a party,
      any of the rights to which have been or will be sublicensed or assigned to
      PDLP.

     

    3.1.4 Intellectual
      Property Rights.
      CVBT
      believes that it has sufficient legal and/or beneficial title and ownership
      to
      grant the licenses to the CVBT Wound Healing IP and the other intellectual
      property rights provided in Section 2 above. CVBT is not aware of any
      allegations that it has violated, or that PDLP by practicing the Wound Healing
      IP as contemplated in the Agreements would violate, any intellectual property
      rights of any third party. To the best of its knowledge, there is no material
      unauthorized use, infringement or misappropriation of any of the Wound Healing
      IP. CVBT is not aware of, nor has it received any communications challenging
      the
      ownership, validity or effectiveness of the Wound Healing IP.

     

    3.1.5 Validity.
      CVBT is
      not aware of any action, suit or inquiry or investigation instituted by any
      federal, state, local or foreign governmental agency or instrumentality which
      questions or threatens the validity of the Agreements.

     

    
      
        
        

      

      
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    3.2 Representations,
      Warranties and Covenants of PDLP.
      PDLP
      represents, warrants and covenants to CVBT as follows:

     

    3.2.1 Organization.
      PDLP is
      a limited partnership duly organized, validly existing and in good standing
      under the laws of State of Nevada with full partnership power and authority
      adequate for executing and delivering and performing its obligations under
      this
      Agreement.

     

    3.2.2 Authorization.
      The
      execution, delivery and performance of this Agreement have been duly authorized
      by all necessary partnership action on the part of PDLP, and this Agreement
      shall constitute a legal, valid and binding obligation of PDLP, enforceable
      against PDLP in accordance with its terms, subject to laws of general
      application relating to bankruptcy, insolvency and the relief of
      debtors.

     

    3.2.3 Other
      Agreements.
      PDLP
      shall not enter into any agreement, make any commitment, take any action or
      fail
      to take any action that would contravene any material provisions of, or
      materially derogate or restrict any of the rights or licenses granted to CVBT
      under this Agreement.

     

    3.2.4 Sublicenses.
      PDLP
      agrees to abide and be bound by the terms of the sublicenses granted to it
      in
      accordance with the terms of this Agreement by CVBT under any Third Party
      Agreement or agreement with a third party.

     

    3.2.5 Non-Solicitation.
      PDLP
      shall not, during the term of this Agreement, without the prior written consent
      of CVBT, solicit the employment of any person, in any capacity, who, at any
      time
      during the term of this Agreement, shall have been an officer, director,
      employee or agent of CVBT or any of its Affiliates.

     

    3.2.6 Validity.
      PDLP is
      aware of no action, suit or inquiry or investigation instituted by any federal,
      state, local or foreign governmental agency or instrumentality which questions
      or threatens the validity of the Agreements.

     

    4. Patents.

     

    4.1 Derived
      from the Development.
      During
      the term of this Agreement, CVBT shall direct and cause appropriate patent
      applications to be prepared, filed and prosecuted in all relevant territories,
      in a timely fashion, with respect to any inventions included in the Program
      IP
      arising out of inventions made by CVBT employees or consultants that CVBT deems
      appropriate. CVBT shall cause any patents issuing thereon to be maintained
      and
      enforced. The expenses of preparing, prosecuting and maintaining such patents
      shall be borne by CVBT. CVBT shall have the right, in its sole discretion,
      to
      enforce any patents issued in conjunction with the Program IP.

     

    4.2 Rights
      After Termination of Agreements.
      After
      the expiration or termination of this Agreement and the Development Agreement,
      CVBT shall have the exclusive right, at its sole expense, to prepare and
      prosecute, in its name, patent applications, and to maintain patents issued
      with
      respect to the Program IP or the Wound Healing IP. CVBT shall have the right,
      in
      its sole discretion, to enforce any patents issued with regard to the Program
      IP
      and/or Wound Healing IP.

     

    
      
        
        

      

      
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    5. Confidential
      Information.
      Any
      party receiving Confidential Information shall maintain the confidential and
      proprietary status of such Confidential Information, keep such Confidential
      Information and each part thereof within its possession or under its control
      sufficient to prevent any activity with respect to the Confidential Information
      that is not specifically authorized or contemplated by this Agreement, use
      all
      commercially reasonable efforts to prevent the disclosure of any Confidential
      Information to any other Person, and use commercially reasonable efforts to
      ensure that such Confidential Information is used only for those purposes
      specifically authorized or contemplated herein; provided, however, that such
      restriction shall not apply to any Confidential Information that is (a)
      independently developed by the receiving party outside the scope of this
      Agreement or the Development Agreement (provided, however, that such restriction
      shall apply to any technology licensed by CVBT to PDLP under this Agreement),
      (b) in the public domain at the time of its receipt or thereafter becomes part
      of the public domain through no fault of the receiving party, (c) received
      without an obligation of confidentiality from a third party having the right
      to
      disclose such information, (d) released from the restrictions of this Section
      4
      by the express written consent of the disclosing party, (e) disclosed to any
      permitted assignee, permitted sublicensee or permitted subcontractor of CVBT
      or
      PDLP under the Agreements (if such assignee, sublicensee or subcontractor is
      subject to the provisions of this Section 4 or substantially similar provisions)
      or (f) required by law, statute, rule or court order to be disclosed provided
      the receiving party promptly provides sufficient notice to the disclosing party
      so that the disclosing party may seek a protective order or other confidential
      treatment (the disclosing party shall, however, use commercially reasonable
      efforts to obtain confidential treatment of any such disclosure). The
      obligations set forth in this Section 4 shall survive for a period of ten years
      from the expiration or termination (other than by exercise) of the Purchase
      Option. Without limiting the generality of the foregoing, CVBT and PDLP each
      shall use commercially reasonable efforts to obtain, if not already in place,
      confidentiality agreements from their respective employees and agents, similar
      in scope to this Section 4, to protect the Confidential
      Information.

     

    6. Permitted
      Disclosures.
      Notwithstanding the provisions of Section 4 hereof, CVBT and PDLP (and their
      permitted sublicensees) may, to the extent necessary, disclose and use
      Confidential Information, consistent with the rights of CVBT and PDLP otherwise
      granted hereunder (a) for the purpose of securing institutional or government
      approval to clinically test or market any wound healing drug developed with
      the
      use of the Program IP or (b) for the purpose of securing patent protection
      for
      an invention within the scope of the Program IP.

     

    7. Disclaimer
      of Warranty; Consequential Damages.

     

    7.1 Disclaimer
      of Warranty.
      Nothing
      in this Agreement shall be construed as a representation made or warranty given
      by any party hereto that the practice by a party hereto of any license granted
      hereunder, or that the use of any Wound Healing IP or Program IP licensed
      hereunder, will not infringe the patent or proprietary rights of any other
      Person. PDLP understands that the Development shall involve technologies that
      have not been approved by any regulatory authority and that CVBT does not
      guaranty the safety or usefulness of any wound healing product developed with
      the Wound Healing IP or the Program IP. In addition, CVBT and PDLP acknowledge
      that the Wound Healing IP or Program IP is licensed to PDLP and sublicensed
      to
      CVBT hereunder as is, and CVBT and PDLP expressly disclaim and hereby waive,
      release and renounce any warranty, express or implied, with respect to such
      Wound Healing IP or Program IP, including, without limitation, any warranty
      of
      merchantability, fitness for a particular purpose or noninfringement. Except
      as
      expressly set forth in this Agreement, CVBT and PDLP disclaim all warranties
      of
      any nature, express or implied.

     

    
      
        
        

      

      
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    7.2 Consequential
      Damages.
      None of
      the parties to this agreement shall be entitled to recover from another party
      hereto any special, incidental, consequential or punitive damages.

     

    8. Indemnification.

     

    8.1 Indemnification
      by CVBT.
      CVBT
      shall indemnify the PDLP Indemnitees, pay on demand and protect, defend, save
      and hold harmless each PDLP Indemnitee from and against any and all Claims
      incurred by or asserted against any PDLP Indemnitee of whatever kind or nature,
      including, without limitation, any claim or liability based upon negligence,
      warranty, strict liability, violation of government regulation or infringement
      of patent or other propriety rights, arising from or occurring as a result
      of
      (a) any use of the Program IP by CVBT or any Affiliate, agent or sublicensee
      of
      CVBT (other than PDLP in contravention of the terms of this Agreement), (b)
      any
      of the Development or any other services to be performed by CVBT during the
      term
      of the Agreements pursuant to the Agreements, including, without limitation,
      any
      workers’ compensation claim by any CVBT employee or consultant or other Person
      or (c) subject to Section 7.2, any breach of the Agreements by CVBT, except,
      with respect to PDLP Indemnitees, in cases in which Claims of PDLP Indemnitees
      are based upon the gross negligence or willful misconduct of an PDLP Indemnitee.
      An PDLP Indemnitee shall promptly notify CVBT of any Claim with respect to
      which
      an PDLP Indemnitee is seeking indemnification hereunder, upon becoming aware
      thereof, and permit CVBT at CVBT’s cost to defend against such Claim and shall
      cooperate in the defense thereof.

     

    8.2 Indemnification
      by PDLP.
      PDLP
      shall indemnify the CVBT Indemnitees, pay on demand and protect, defend, save
      and hold harmless each CVBT Indemnitee from and against any and all Claims
      incurred by or asserted against any CVBT Indemnitee of whatever kind or nature,
      including, without limitation, any claim or liability based upon negligence,
      warranty, strict liability, violation of government regulation or infringement
      of patent or other propriety rights, arising from or occurring as a result
      of
      (a) any use of the Wound Healing IP or Program IP by PDLP or any sublicensee
      of
      PDLP (other than the use of such by CVBT whether pursuant to the Agreements
      or
      otherwise) or (b) subject to Section 7.2, any breach of the Agreements by PDLP,
      except, with respect to CVBT Indemnitees, in cases in which Claims are based
      upon the gross negligence or willful misconduct of a CVBT Indemnitee. An
      Indemnitee hereunder shall promptly notify PDLP of any Claim with respect to
      which such Indemnitee is seeking indemnification hereunder, upon becoming aware
      thereof, and permit PDLP at PDLP’s cost to defend against such Claim and shall
      cooperate in the defense thereof.

     

    
      
        
        

      

      
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    8.3 Defense
      of Claims.
      None of
      CVBT or PDLP shall enter into, or permit, any settlement of any Claim for which
      indemnification is being sought by such party hereunder without the express
      written consent of each other party (or a CVBT or PDLP Indemnitee, as the case
      may be), which consent shall not be unreasonably withheld or delayed. Each
      party
      may, at its option and expense, have its own counsel participate in any
      proceeding which is under the direction of another party (the “Indemnifying
      Party”) and will cooperate with the Indemnifying Party and its insurer in the
      disposition of any such matter; provided, however, that if the Indemnifying
      Party shall not defend such Claim, the other party shall have the right to
      defend such Claim itself and recover from the Indemnifying Party all reasonable
      attorneys’ fees and expenses incurred by it during the course of such
      defense.

     

    9. Term
      and Termination.

     

    9.1 Term.
      This
      Agreement shall be effective as of the date hereof and shall continue in full
      force and effect indefinitely, unless terminated earlier as provided in Sections
      9.2, 9.3, 9.4 and 9.5 hereof.

     

    9.2 Termination
      by Mutual Agreement.
      By
      mutual agreement, the parties hereto may at any time terminate this Agreement
      and the Development on mutually acceptable terms.

     

    9.3 Termination
      of Development.
      At any
      time, and upon notice to PDLP, CVBT may elect to terminate the Development
      process due to insufficient progress, overwhelming competition or outright
      inability to make progress toward a commercially marketable wound healing
      drug.

     

    9.4 Termination
      by CVBT or PDLP for Breach.
      Either
      CVBT or PDLP shall have the right to terminate this Agreement, effective as
      set
      forth in a written notice of the occurrence of a material breach of this
      Agreement. Such termination must be preceded by written notice delivered to
      the
      breaching party specifying the breach and offering a reasonable opportunity
      and
      no less than thirty (30) days for the breaching party to cure such
      breach.

     

    9.5 Termination
      After Full Payment.
      This
      Agreement shall terminate upon payment in full by CVBT to PDLP of the maximum
      amount set forth in Section 5 of the Development Agreement.

     

    9.6 Effect
      of Termination.
      If this
      Agreement is terminated pursuant to Sections 9.2 or 9.3, neither party shall
      have any liability to the other except as agreed upon pursuant to the
      termination and the ownership of the Wound Healing IP and the Program IP
      including, without limitation, any patents that may issue based on the Wound
      Healing IP or Program IP, will revert to CVBT without further action on the
      part
      of any of the parties. If the Agreement is terminated pursuant to Section 9.4,
      the parties shall have such remedies as may be available under applicable law.
      If this Agreement is terminated pursuant to Section 9.5, all right, title and
      interest in the Wound Healing IP and the Program IP shall revert to CVBT without
      further action on the part of any of the parties. However, to the extent that
      evidence of any such reversion is required to be placed in a writing, PDLP
      will,
      at CVBT’s request, execute and deliver to CVBT specific assignments of the Wound
      Healing IP or the Program IP and execute, acknowledge and deliver to CVBT such
      other documents and take such further actions as CVBT may consider necessary
      or
      appropriate to confirm or vest title in such intellectual property in
      CVBT.

     

    
      
        
        

      

      
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    9.7 Continuing
      Obligation to Make Payments.
      Notwithstanding anything contained herein to the contrary, upon termination
      of
      this Agreement, the obligation to pay any amounts payable by any party to
      another party which accrued prior to such termination shall
      survive.

     

    10. Miscellaneous.

     

    10.1 No
      Implied Waivers; Rights Cumulative.
      No
      failure on the part of CVBT or PDLP to exercise and no delay in exercising
      any
      right, power, remedy or privilege under this Agreement or provided by statute
      or
      at law or in equity or otherwise, including, without limitation, the right
      or
      power to terminate this Agreement, shall impair, prejudice or constitute a
      waiver of any such right, power, remedy or privilege or be construed as a waiver
      of any breach of this Agreement or as an acquiescence therein, nor shall any
      single or partial exercise of any such right, power, remedy or privilege
      preclude any other or further exercise thereof or the exercise of any other
      right, power, remedy or privilege.

     

    10.2 Force
      Majeure.
      CVBT
      and PDLP shall each be excused for any failure or delay in performing any of
      their respective obligations under this Agreement, if such failure or delay
      is
      caused by a force, effect, cause or circumstance beyond the control of the
      nonperforming party.

     

    10.3 Relationship
      of the Parties.
      Nothing
      contained in this Agreement is intended or is to be construed to constitute
      CVBT
      and PDLP as partners or joint venturers or one party as an employee of any
      other
      party. Except as expressly provided herein, no party hereto shall have any
      express or implied right or authority to assume or create any obligations on
      behalf of or in the name of any other party or to bind any other party to any
      contract, agreement or undertaking with any third party.

     

    10.4 Notices.
      All
      notices, requests and other communications to CVBT or PDLP hereunder shall
      be in
      writing (including telecopy or electronic mail (“e-mail”) transmissions), shall
      refer specifically to this Agreement and shall be personally delivered or sent
      by telecopy, facsimile or e-mail transmission or by registered mail or certified
      mail, return receipt requested and postage prepaid, or by reliable overnight
      courier service, in each case to the respective address specified below (or
      to
      such address as may be specified in writing to the other party
      hereto):

     

    
      
        	If to CVBT, addressed
                to:	CardioVascular
                BioTherapeutics, Inc.
                1635
                  Village Center Circle

                Suite
                  250

                Las
                  Vegas, Nevada 89134

                Attention:
                  Mickael A. Flaa, CFO

                Fax
                  No.: 702-304-2120

                E-mail:
                  mflaa@cvbt.com

              


      

    

     

    with
      a
      copy to the attention of General Counsel (using the same information above
      except if via email, then also to vroth@cvbt.com)


    
      
        
        

      

      
        8

        
          

        

      

      
        
        

      

    

     

    
      	If to PDLP, addressed
              to: ProDerm,
              LP	
              1000
                Rancho Circle

              Las
                Vegas, NV 89107

              Attention:
                Christopher Moore, MD

              Fax
                No.: 702-878-0103

              E-mail:
                ahnsgoc@aol.com

            


    

     

    with
      a
      copy to the attention of VP and Representative of General Partners (using the
      same information above except if via email, then also to fsslv@yahoo.com)

     

    Each
      party shall provide each other party with copies of any notices sent hereunder,
      with such copies sent at the same time as the original notice. Any notice or
      communication given in conformity with this Section 10.4 shall be deemed to
      be
      effective when received by the addressee, if delivered by hand, telecopy or
      e-mail transmission, three days after mailing, if mailed, and one business
      day
      after delivery either to a reliable overnight courier service or via any
      electronic means permissible under this Agreement provided the sender has
      confirmation of successful transmission.

     

    10.5 Successors
      and Assigns.
      The
      terms and provisions of this Agreement shall inure to the benefit of, and be
      binding upon, CVBT, PDLP and their respective successors and assigns; provided,
      however, that CVBT and PDLP may not assign or otherwise transfer any of their
      respective rights and interests, nor delegate any of their respective
      obligations, hereunder, including, without limitation, pursuant to a merger
      or
      consolidation, without the prior written consent of the other party hereto;
      provided further, however, that CVBT may fully assign its respective rights
      and
      interests, and delegate its respective obligations, hereunder, effective upon
      written notice thereof (a) to an Affiliate if such Affiliate assumes all of
      the
      obligations of CVBT hereunder and this Agreement remains binding upon CVBT;
      or
      (b) to any Person that acquires all or substantially all of the assets of CVBT
      or which is the surviving Person in a merger or consolidation with CVBT if
      such
      Person assumes all the obligations of CVBT hereunder. Notwithstanding the
      foregoing, PDLP shall not have the right to assign its rights to the Wound
      Healing IP granted herein without the written consent of CVBT. Any attempt
      to
      assign or delegate any portion of this Agreement in violation of this Section
      10.5 shall be null and void. Subject to the foregoing any reference to CVBT
      or
      PDLP hereunder shall be deemed to include the successors thereto and assigns
      thereof.

     

    10.6 Amendments.
      No
      amendment, modification, waiver, termination or discharge of any provision
      of
      this Agreement, nor consent by CVBT or PDLP to any departure therefrom, shall
      in
      any event be effective unless the same shall be in writing specifically
      identifying this Agreement and the provision intended to be amended, modified,
      waived, terminated or discharged and signed by CVBT and PDLP, and each
      amendment, modification, waiver, termination or discharge shall be effective
      only in the specific instance and for the specific purpose for which given
      and
      shall not be deemed to be a wavier, termination or discharge for any subsequent,
      individual or repeated similar or different instance or purpose. No provision
      of
      this Agreement shall be varied, contradicted or explained by any other
      agreement, course of dealing or performance or any other matter not set forth
      in
      an agreement in writing and signed by CVBT and PDLP.

     

    
      
        
        

      

      
        9

        
          

        

      

      
        
        

      

    

     

    10.7 Governing
      Law.
      This
      Agreement shall be governed by and construed in accordance with the laws of
      the
      State of Delaware, as applied to contracts made and performed entirely within
      the State of Delaware. Except as otherwise provided herein, any claim or
      controversy arising out of or related to this contract or any breach hereof
      shall be submitted to a court of competent jurisdiction in the State of Nevada,
      and the parties hereby consent to the jurisdiction and venue of such
      court.

     

    10.8 Severability.
      If any
      provision hereof should be held invalid, illegal or unenforceable in any respect
      in any jurisdiction, then, to the fullest extent permitted by law, (a) all
      other
      provisions hereof shall remain in full force and effect in such jurisdiction
      and
      shall be liberally construed in order to carry out the intentions of the parties
      hereto as nearly as may be possible and (b) such invalidity, illegality or
      unenforceability shall not affect the validity, legality or enforceability
      of
      such provision in any other jurisdiction. To the extent permitted by applicable
      law, CVBT and PDLP hereby waive any provision of law that would render any
      provision hereof prohibited or unenforceable in any respect.

     

    10.9 Trading
      Limitations.
      In
      addition to being Confidential Information, the results of the Development
      will
      be deemed material nonpublic information until disclosed to the public by CVBT
      in a report to the Securities and Exchange Commission (the “SEC”), or, if
      applicable and/or permissible and/or appropriate, in a press release or
      published on CVBT’s web site in an event where a filing with the SEC is not
      required or is discretionary. If PDLP is in possession of, or otherwise has
      knowledge of, the results of the Development before such public disclosure
      by
      CVBT, PDLP acknowledges and agreed that it may not trade in CVBT securities.
      Further, PDLP agrees to obtain a similar acknowledgment agreement from its
      partners.

     

    10.10 Counterparts.
      This
      Agreement may be executed in any number of counterparts, each of which
      counterpart, when so executed and delivered, shall be deemed to be an original,
      and all of which counterparts, taken together, shall constitute one and the
      same
      instrument.

     

    10.11 Entire
      Agreement.
      This
      Agreement, together with any agreements referenced herein, constitute, on and
      as
      of the date hereof, the entire agreement of CVBT and PDLP with respect to the
      subject matter hereof, and all prior or contemporaneous understandings or
      agreements, whether written or oral, between CVBT and PDLP with respect to
      such
      subject matter are hereby superseded in their entirety.

     

     

     

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      OF THIS PAGE INTENTIONALLY LEFT BLANK]


    
      
        
        

      

      
        10

        
          

        

      

      
        
        

      

    


    IN
      WITNESS WHEREOF the parties have executed this Agreement as of the date first
      above written.

     

    
      	 	 	 
	 	CARDIOVASCULAR
              BIOTHERAPEUTICS, INC.
	 
 	 
 	 
 
	 	By:  	/s/ Daniel
              C.
              Montano
	 	
              

              Daniel
                C. Montano

              Its
                President and Chief Executive Officer

            
	 	 


    

    
       

      
        	 	 	 
	 	ProDerm,
                LP
	 
 	 
 	 
 
	 	By:  	VD-1
                ,
                LLC
	 	
                
Its
                General Partner
	 	 


      

       

       

      
        	 	By:	 /s/John Laub
	 	 	
                
Its
                Manager


      

    

     

    
      
        
        

      

      
        11

        
          

        

      

      
        
        

      

    


    SCHEDULE
      1.1

     

    DEFINITIONS

     

    “Affiliate”
      of a person shall mean a Person that directly or indirectly through one or
      more
      intermediaries, controls, is controlled by or is under common control with
      such
      Person. “Control” (and, with correlative meanings, the terms “controlled by” and
“under common control with”) shall mean the possession of the power to direct or
      cause the direction of the management and policies of such Person, whether
      through the ownership of voting stock, by contract or otherwise. In the case
      of
      a corporation, “control” shall mean, among other things, the direct or indirect
      ownership of more than 50% of its outstanding voting stock.

     

    “Agreements”
      shall mean the Technology Agreement and the Development Agreement.

     

    “Claim”
      shall mean any and all liabilities, damages, losses, settlements, claims,
      actions, suits, penalties, fines, costs or expenses (including, without
      limitation, reasonable attorneys’ fees).

     

    “Confidential
      Information” shall mean the Wound Healing IP and all Program IP developed by
      CVBT (and its Affiliates) and disclosed to PDLP or by PDLP to CVBT pursuant
      to
      the Agreements.

     

    “CVBT
      Indemnitee” shall mean CVBT, its successors and assigns, and the directors,
      officers, employees, agents and counsel thereof.

     

    “Development”
      shall mean the further development of the Program IP for the purpose of
      advancing the FDA Process toward development of a wound healing drug approved
      for commercialization by the FDA.

     

    “Development
      Agreement” shall mean the Development Agreement dated as of July 8, 2008,
      between CVBT and PDLP, as amended, modified or supplemented from time to
      time.

     

    “FDA”
      shall mean the United States Food and Drug Administration or any successor
      agency or authority, the approval of which is required to market biologic
      products in the United States.

     

    “FDA
      Process” shall mean the clinical trials and other activities necessary to obtain
      FDA approval for commercialization.

     

    “Force
      Majeure” shall mean any act of God, any accident explosion, fire, storm,
      earthquake, flood, drought, peril of the sea, riot, embargo, war or foreign,
      federal, state or municipal order of general application, seizure, requisition
      or allocation, any failure or delay of transportation, shortage of or inability
      to obtain supplies, equipment, fuel or labor or any other circumstance or event
      beyond the reasonable control of the party relying upon such circumstance or
      event.

     

    
      
        
        

      

      
        1.1-1

        
          

        

      

      
        
        

      

    

     

    “Person”
      shall mean any individual, partnership, corporation, firm, association,
      unincorporated organization, joint venture, trust or other entity.

     

    “Program
      IP” shall mean the Wound Healing IP and any enhancements, substitutions, or
      improvements to the Wound Healing IP, as well as any new data or know-how
      associated therewith, that is discovered, developed or otherwise acquired by
      CVBT pursuant to the Development Agreement.

     

    “PDLP
      Indemnitee” shall mean PDLP, its successors and assigns, and the directors,
      officers, employees, agents and counsel thereof.

     

    “Technology
      Agreement” shall mean this Technology License Agreement dated as of July 8,
      2008, between CVBT and PDLP, as amended, modified or supplemented from time
      to
      time.

     

    “Wound
      Healing IP” shall be the intellectual property described in Schedule 2.1 to the
      Development Agreement which schedule is incorporated herein by this
      reference.

     

    
      
        
        

      

      
        1.1-2