`[Federal Register Volume 89, Number 239 (Thursday, December 12, 2024)]
[Rules and Regulations]
[Pages 100361-100377]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2024-29276]


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ENVIRONMENTAL PROTECTION AGENCY

40 CFR Parts 9 and 721

[EPA-HQ-OPPT-2022-0771; FRL-11912-02-OCSPP]
RIN 2070-AB27


Significant New Use Rules on Certain Chemical Substances (22-
4.5e)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Final rule.

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SUMMARY: EPA is issuing significant new use rules (SNURs) under the 
Toxic Substances Control Act (TSCA) for certain chemical substances 
that were

[[Page 100362]]

the subject of premanufacture notices (PMNs) and are also subject to an 
Order issued by EPA pursuant to TSCA. The SNURs require persons to 
notify EPA at least 90 days before commencing the manufacture (defined 
by statute to include import) or processing of any of these chemical 
substances for an activity that is designated as a significant new use 
in the SNUR. The required notification initiates EPA's evaluation of 
the conditions of that use for that chemical substance. In addition, 
the manufacture or processing for the significant new use may not 
commence until EPA has conducted a review of the required notification; 
made an appropriate determination regarding that notification; and 
taken such actions as required by that determination.

DATES: This rule is effective February 10, 2025. For purposes of 
judicial review, this rule shall be promulgated at 1 p.m. (EST) on 
December 26, 2024.

ADDRESSES: The docket for this action, identified under docket 
identification (ID) number EPA-HQ-OPPT-2022-0771, is available online 
at https://www.regulations.gov or in person at the Office of Pollution 
Prevention and Toxics Docket (OPPT Docket) in the Environmental 
Protection Agency Docket Center (EPA/DC). Please review the visitor 
instructions and additional information about the docket available at 
https://www.epa.gov/dockets.

FOR FURTHER INFORMATION CONTACT: For technical information: Jennise 
Armstead, New Chemicals Division (7405M), Office of Pollution 
Prevention and Toxics, Environmental Protection Agency, 1200 
Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: 
(202) 566-1486; email address: [email protected].
    For general information on SNURs: William Wysong, New Chemicals 
Division (7405M), Office of Pollution Prevention and Toxics, 
Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, 
DC 20460-0001; telephone number: (202) 564-4163; email address: 
[email protected].
    For general information on TSCA: The TSCA-Hotline, ABVI-Goodwill, 
422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 
554-1404; email address: [email protected].

SUPPLEMENTARY INFORMATION:

I. Executive Summary

A. What is the Agency's authority for taking this action?

    TSCA section 5(a)(2) (15 U.S.C. 2604(a)(2)) authorizes EPA to 
determine that a use of a chemical substance is a ``significant new 
use.'' EPA must make this determination by rule after considering all 
relevant factors, including the factors in TSCA section 5(a)(2).

B. What action is the Agency taking?

    EPA is finalizing SNURs under TSCA section 5(a)(2) for the chemical 
substances identified in Unit III. These chemical substances were the 
subject of PMNs and are also subject to an Order issued by EPA pursuant 
to TSCA section 5(e)(1)(A), as required by the determinations made 
under TSCA section 5(a)(3)(B). The SNURs identify as significant new 
uses any manufacturing, processing, use, distribution in commerce, or 
disposal that does not conform to the restrictions imposed by the 
underlying TSCA Orders, consistent with TSCA section 5(f)(4). The SNURs 
require persons who intend to manufacture or process any of these 
chemical substances for an activity that is designated as a significant 
new use in the SNURs to notify EPA at least 90 days before commencing 
that activity.
    Previously, EPA proposed SNURs for these chemical substances in the 
Federal Register of June 11, 2024 (89 FR 49121 (FRL-11912-01-OCSPP)). 
The docket includes information considered by the Agency in developing 
the proposed and final rules, including public comments and EPA's 
responses to the comments received as discussed in Unit II.E.

C. Does this action apply to me?

1. General Applicability
    This action applies to you if you manufacture, process, or use the 
chemical substances identified in Unit III. The following list of North 
American Industrial Classification System (NAICS) codes is not intended 
to be exhaustive, but rather provides a guide to help readers determine 
whether this document applies to them. Potentially affected entities 
may include:
     Manufacturers or processors of one or more subject 
chemical substances (NAICS codes 325 and 324110), e.g., chemical 
manufacturing and petroleum refineries.
2. Applicability to Importers and Exporters
    This action may also apply to certain entities through pre-existing 
import certification and export notification requirements under TSCA 
(https://www.epa.gov/tsca-import-export-requirements).
    Chemical importers are subject to TSCA section 13 (15 U.S.C. 2612), 
the requirements in 19 CFR 12.118 through 12.127, 19 CFR 127.28, and 40 
CFR part 707, subpart B. Chemical importers must certify that the 
shipment of the chemical substance complies with all applicable rules 
and orders under TSCA, including regulations issued under TSCA sections 
5, 6, 7 and Title IV.
    Pursuant to 40 CFR 721.20, any persons who export or intend to 
export a chemical substance identified in Unit III. are subject to the 
export notification provisions of TSCA section 12(b) (15 U.S.C. 
2611(b)) and must comply with the export notification requirements in 
40 CFR part 707, subpart D.

D. What are the incremental economic impacts of this action?

    EPA has evaluated the potential costs of establishing SNUN 
reporting requirements for potential manufacturers and processors of 
the chemical substances identified in Unit III. This analysis, which is 
available in the docket, is briefly summarized here.
1. Estimated Costs for SNUN Submissions
    A SNUR requires that any person who intends to engage in such 
activity in the future must first notify EPA by submitting a SNUN. If a 
SNUN is submitted, costs are an estimated $45,000 per SNUN submission 
for large business submitters and $14,500 for small business 
submitters. These estimates include the cost to prepare and submit the 
SNUN (including registration for EPA's Central Data Exchange (CDX)), 
and the payment of a user fee. Businesses that submit a SNUN would be 
subject to either a $37,000 user fee required by 40 CFR 
700.45(c)(2)(ii) and (d), or, if they are a small business as defined 
at 13 CFR 121.201, a reduced user fee of $6,480 (40 CFR 
700.45(c)(1)(ii) and (d)). These estimates reflect the costs and fees 
as they are known at the time of this rulemaking.
2. Estimated Costs for Export Notifications
    EPA has also evaluated the potential costs associated with the pre-
existing export notification requirements under TSCA section 12(b) and 
the implementing regulations at 40 CFR part 707, subpart D. For persons 
exporting a substance that is the subject of a SNUR, a one-time notice 
to EPA must be provided for the first export or intended export to a 
particular country. The total costs of export notification will vary by 
chemical, depending on the number of required notifications (i.e., the 
number of countries to which the chemical is

[[Page 100363]]

exported). While EPA is unable to make any estimate of the likely 
number of export notifications for the chemical substances covered by 
these SNURs, as stated in the accompanying economic analysis, the 
estimated cost of the export notification requirement on a per unit 
basis is approximately $106.

II. Background

A. General Information About SNURS

    Unit II. of the proposed rule provides general information about 
SNURs, and additional information about EPA's new chemical program is 
available at https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca.

B. Applicability of the Significant New Use Designation

    To establish a significant new use, EPA must determine that the use 
is not ongoing. As discussed in Unit II.E. of the proposed rule, EPA 
concluded that the proposed significant new uses were not ongoing. If 
EPA subsequently determines that such a use was ongoing as of the date 
of publication of the proposed rule and did not cease prior to issuance 
of the final rule, EPA will not designate that use as a significant new 
use in the final rule. EPA has no information to suggest that any of 
the significant new uses identified in this rule are ongoing.
    As discussed in the Federal Register of April 24, 1990 (55 FR 17376 
(FRL-3658-5)), EPA has decided that the intent of TSCA section 
5(a)(1)(B) is best served by designating a use as a significant new use 
as of the date of publication of the proposed rule rather than as of 
the effective date of the final rule. The objective of EPA's approach 
is to ensure that a person cannot impede finalization of a SNUR by 
initiating a significant new use after publication of the proposed rule 
but before the effective date of the final rule. Uses arising after the 
publication of the proposed rule are distinguished from uses that are 
identified in the final rule as having been ongoing on the date of 
publication of the proposed rule. The former would be new uses, the 
latter ongoing uses, except that uses that are identified as ongoing as 
of the publication of the proposed rule would not be considered ongoing 
uses if they have ceased by the date of issuance of a final rule.
    In the unlikely event that before a final rule becomes effective a 
person begins commercial manufacturing (including importing) or 
processing of the chemical substances for a use that is designated as a 
significant new use in that final rule, such a person would have to 
cease any such activity upon the effective date of the final rule. To 
resume their activities, these persons would have to first comply with 
all applicable SNUR notification requirements and wait until all TSCA 
prerequisites for the commencement of manufacture or processing have 
been satisfied.
    Issuance of a SNUR for a chemical substance does not signify that 
the chemical substance is listed on the TSCA Chemical Substance 
Inventory (TSCA Inventory). Guidance on how to determine if a chemical 
substance is on the TSCA Inventory is available on the internet at 
https://www.epa.gov/tsca-inventory.

C. Important Information About SNUN Submissions

1. SNUN Submissions
    SNUNs must be submitted on EPA Form No. 7710-25, generated using e-
PMN software, and submitted to the Agency in accordance with the 
procedures set forth in 40 CFR 720.40 and 721.25. E-PMN software is 
available electronically at https://www.epa.gov/reviewing-new-chemicals-under-toxic-substances-control-act-tsca.
2. Development and Submission of Information
    EPA recognizes that TSCA section 5 does not require development of 
any particular new information (e.g., generating test data) before 
submission of a SNUN. There is an exception: If a person is required to 
submit information for a chemical substance pursuant to a rule, order 
or consent agreement under TSCA section 4, then TSCA section 5(b)(1)(A) 
requires such information to be submitted to EPA at the time of 
submission of the SNUN.
    In the absence of a rule, TSCA Order, or consent agreement under 
TSCA section 4 covering the chemical substance, persons are required 
only to submit information in their possession or control and to 
describe any other information known to or reasonably ascertainable by 
them (see 40 CFR 720.50). However, upon review of PMNs and SNUNs, the 
Agency has the authority to require appropriate testing. To assist with 
EPA's analysis of the SNUN, submitters are encouraged, but not 
required, to provide the potentially useful information as identified 
for the chemical substance in Unit III.C. of the proposed rule.
    EPA strongly encourages persons, before performing any testing, to 
consult with the Agency pertaining to protocol selection. Furthermore, 
pursuant to TSCA section 4(h), which pertains to reduction of testing 
in vertebrate animals, EPA encourages consultation with the Agency on 
the use of alternative test methods and strategies (also called New 
Approach Methodologies, or NAMs), if available, to generate the 
recommended test data. EPA encourages dialog with Agency 
representatives to help determine how best the submitter can meet both 
the data needs and the objective of TSCA section 4(h). For more 
information on alternative test methods and strategies to reduce 
vertebrate animal testing, visit https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/alternative-test-methods-and-strategies-reduce.
    The potentially useful information described in Unit III. may not 
be the only means of providing information to evaluate the chemical 
substance associated with the significant new uses. However, submitting 
a SNUN without any test data may increase the likelihood that EPA will 
take action under TSCA section 5(e) or 5(f). EPA recommends that 
potential SNUN submitters contact EPA early enough so that they will be 
able to conduct the appropriate tests.
    SNUN submitters should be aware that EPA will be better able to 
evaluate SNUNs which provide detailed information about human exposure 
and environmental release that may result from the significant new use 
of the chemical substances.

D. Public Comments on Proposed Rule and EPA Responses

    EPA received public comments on the proposed SNURs, and prepared a 
Response to Comment document that provides the Agency responses. The 
comments and the Response to Comment document are available in the 
docket. As described in the Response to Comment document, EPA is 
finalizing these SNURs with the following changes:
     For PMN P-21-56 (40 CFR 721.11868), EPA has reviewed the 
new test data submitted by the PMN submitter and no longer has the 
concern for skin sensitization based on the weight of available 
scientific evidence. The explanation is provided in the revised human 
health risk assessment, which has been added to the docket. EPA is 
modifying the significant new use terms included in the final SNUR. Two 
significant new uses, manufacturing the substance beyond 24 months and 
the requirement that the substance be classified as a skin 
sensitization risk on labels and the Safety Data Sheets, are not 
included in the final SNUR, and the company's

[[Page 100364]]

consent order is being modified accordingly.
     EPA inadvertently assigned the same CFR number to several 
proposed SNURs and has updated the CFR numbering for those SNURs. The 
proposed CFR numbering ranged from Sec. Sec.  721.11860 through 
721.11890, and the corrected CFR numbering ranges from Sec. Sec.  
721.11863 through 721.11893.

III. Chemical Substances Subject to These SNURs

A. What is the designated cutoff date for ongoing uses?

    EPA designates the date of publication of the proposed rule as the 
cutoff date for determining whether the new use is ongoing, i.e., June 
11, 2024 (89 FR 49121 (FRL-11912-01-OCSPP)). This designation is 
explained further in Unit II.B.

B. What information is provided for each chemical substance?

    In Unit III.C. of the proposed rule, EPA provided the following 
information for each chemical substance subject to these SNURs:
     PMN number (the CFR citation assigned in the regulatory 
text section of this document).
     Chemical name (generic name, if the specific name is 
claimed as CBI).
     Chemical Abstracts Service Registry Number (CASRN) or 
Accession Number (if assigned for non-confidential chemical 
identities).
     Basis for the SNUR (e.g., Effective date of and basis for 
the TSCA Order).
     Potentially useful information.
    The regulatory text section of this document specifies the 
activities designated as significant new uses. Certain new uses, 
including production volume limits and other uses designated, may be 
claimed as CBI.
    In addition, as discussed in Unit III.B. of the proposed rule, 
these SNURs include PMN substances that are subject to orders issued 
under TSCA section 5(e)(1)(A), as required by the determinations made 
under TSCA section 5(a)(3)(B). Those TSCA Orders require protective 
measures to limit exposures or otherwise mitigate the potential 
unreasonable risk. As such, the SNURs identify as significant new uses 
any manufacturing, processing, use, distribution in commerce, or 
disposal that does not conform to the restrictions imposed by the 
underlying TSCA Orders, consistent with TSCA section 5(f)(4).

IV. Statutory and Executive Order Reviews

    Additional information about these statutes and Executive orders 
can be found at https://www.epa.gov/laws-regulations-and-executive-orders.

A. Executive Order 12866: Regulatory Planning and Review and Executive 
Order 14094: Modernizing Regulatory Review

    This action establishes SNURs for new chemical substances that were 
the subject of PMNs. The Office of Management and Budget (OMB) has 
exempted these types of actions from review under Executive Order 12866 
(58 FR 51735, October 4, 1993), as amended by Executive Order 14094 (88 
FR 21879, April 11, 2023).

B. Paperwork Reduction Act (PRA)

    According to the PRA (44 U.S.C. 3501 et seq.), an agency may not 
conduct or sponsor, and a person is not required to respond to a 
collection of information that requires OMB approval under PRA, unless 
it has been approved by OMB and displays a currently valid OMB control 
number. The OMB control numbers for EPA's regulations in title 40 of 
the CFR, after appearing in the Federal Register, are listed in 40 CFR 
part 9, and included on the related collection instrument or form, if 
applicable.
    The information collection requirements related to SNURs have 
already been approved by OMB pursuant to PRA under OMB control number 
2070-0038 (EPA ICR No. 1188). This action does not impose any burden 
requiring additional OMB approval. If an entity were to submit a SNUN 
to the Agency, the annual burden is estimated to average between 30 and 
170 hours per submission. This burden estimate includes the time needed 
to review instructions, search existing data sources, gather and 
maintain the data needed, and complete, review, and submit the required 
SNUN.
    EPA always welcomes your feedback on the burden estimate. Send any 
comments about the accuracy of the burden estimate, and any suggested 
methods for improving the collection instruments or instruction or 
minimizing respondent burden, including through the use of automated 
collection techniques.

C. Regulatory Flexibility Act (RFA)

    I certify that this action will not have a significant economic 
impact on a substantial number of small entities under the RFA (5 
U.S.C. 601 et seq.). The requirement to submit a SNUN applies to any 
person (including small or large entities) who intends to engage in any 
activity described in the final rule as a ``significant new use.'' 
Because these uses are ``new,'' based on all information currently 
available to EPA, EPA has concluded that no small or large entities 
presently engage in such activities.
    A SNUR requires that any person who intends to engage in such 
activity in the future must first notify EPA by submitting a SNUN. 
Although some small entities may decide to pursue a significant new use 
in the future, EPA cannot presently determine how many, if any, there 
may be. However, EPA's experience to date is that, in response to the 
promulgation of SNURs covering over 1,000 chemicals, the Agency 
receives only a small number of notices per year. For example, the 
number of SNUNs received was 7 in Federal fiscal year (FY) 2020, 13 in 
FY2021, 11 in FY2022, and 15 in FY2023, and only a fraction of these 
were from small businesses.
    In addition, the Agency currently offers relief to qualifying small 
businesses by reducing the SNUN submission fee from $37,000 to $6,480. 
This lower fee reduces the total reporting and recordkeeping cost of 
submitting a SNUN to about $14,500 per SNUN submission for qualifying 
small firms. Therefore, the potential economic impacts of complying 
with these SNURs are not expected to be significant or adversely impact 
a substantial number of small entities. In a SNUR that published in the 
Federal Register of June 2, 1997 (62 FR 29684) (FRL-5597-1), the Agency 
presented its general determination that SNURs are not expected to have 
a significant economic impact on a substantial number of small 
entities, which was provided to the Chief Counsel for Advocacy of the 
Small Business Administration.

D. Unfunded Mandates Reform Act (UMRA)

    This action does not contain an unfunded mandate of $100 million or 
more (in 1995 dollars) in any one year as described in UMRA, 2 U.S.C. 
1531-1538, and does not significantly or uniquely affect small 
governments. Based on EPA's experience with proposing and finalizing 
SNURs, State, local, and Tribal governments have not been impacted by 
SNURs, and EPA does not have any reasons to believe that any State, 
local, or Tribal government will be impacted by these SNURs. In 
addition, the estimated costs of this action to the private sector do 
not exceed $183 million or more in any one year (the 1995 dollars are 
adjusted to 2023 dollars for inflation using the GDP implicit price 
deflator). The estimated costs for this action are discussed in Unit 
I.D

[[Page 100365]]

E. Executive Order 13132: Federalism

    This action will not have federalism implications as specified in 
Executive Order 13132 (64 FR 43255, August 10, 1999), because it is not 
expected to have a substantial direct effect on States, on the 
relationship between the National Government and the States, or on the 
distribution of power and responsibilities among the various levels of 
government. Accordingly, the requirements of Executive Order 13132 do 
not apply to this action.

F. Executive Order 13175: Consultation and Coordination With Indian 
Tribal Governments

    This action will not have Tribal implications as specified in 
Executive Order 13175 (65 FR 67249, November 9, 2000), because it is 
not expected to have substantial direct effects on Indian Tribes, 
significantly or uniquely affect the communities of Indian Tribal 
governments and does not involve or impose any requirements that affect 
Indian Tribes. Accordingly, the requirements of Executive Order 13175 
do not apply to this action.

G. Executive Order 13045: Protection of Children From Environmental 
Health Risks and Safety Risks

    This action is not subject to Executive Order 13045 (62 FR 19885, 
April 23, 1997), because it does not concern an environmental health or 
safety risk. Since this action does not concern a human health risk, 
EPA's 2021 Policy on Children's Health also does not apply. Although 
the establishment of these SNURs do not address an existing children's 
environmental health concern because the chemical uses involved are not 
ongoing uses, SNURs require that persons notify EPA at least 90 days 
before commencing manufacture (defined by statute to include import) or 
processing of the identified chemical substances for an activity that 
is designated as a significant new use by the SNUR. This notification 
allows EPA to assess the intended uses to identify potential risks and 
take appropriate actions before the activities commence.

H. Executive Order 13211: Actions Concerning Regulations That 
Significantly Affect Energy Supply, Distribution, or Use

    This action is not a ``significant energy action'' as defined in 
Executive Order 13211 (66 FR 28355, May 22, 2001), because it is not 
likely to have a significant adverse effect on the supply, 
distribution, or use of energy.

I. National Technology Transfer and Advancement Act (NTTAA)

    This action does not involve any technical standards subject to 
NTTAA section 12(d) (15 U.S.C. 272 note).

J. Executive Order 12898: Federal Actions To Address Environmental 
Justice in Minority Populations and Low-Income Populations and 
Executive Order 14096: Revitalizing Our Nation's Commitment to 
Environmental Justice for All

    EPA believes that this type of action does not concern human health 
or environmental conditions and therefore cannot be evaluated with 
respect to potentially disproportionate and adverse effects on 
communities with environmental justice concerns in accordance with 
Executive Orders 12898 (59 FR 7629, February 16, 1994) and 14096 (88 FR 
25251, April 26, 2023). Although this action does not concern human 
health or environmental conditions, the notifications required by these 
SNURs allows EPA to assess the intended uses to identify potential 
disproportionate risks and take appropriate actions before the 
activities commence.

K. Congressional Review Act (CRA)

    This action is subject to the CRA (5 U.S.C. 801 et seq.), and EPA 
will submit a rule report to each House of the Congress and to the 
Comptroller General of the United States. This action is not a ``major 
rule'' as defined by 5 U.S.C. 804(2).

List of Subjects

40 CFR Part 9

    Environmental protection, Reporting and recordkeeping requirements.

40 CFR Part 721

    Environmental protection, Chemicals, Hazardous substances, 
Reporting and recordkeeping requirements.

    Dated: December 6, 2024.
Kevin DeBell,
Acting Director, Office of Pollution Prevention and Toxics.

    Therefore, for the reasons stated in the preamble, 40 CFR chapter I 
is amended as follows:

PART 9--OMB APPROVALS UNDER THE PAPERWORK REDUCTION ACT

0
1. The authority citation for part 9 continues to read as follows:

    Authority: 7 U.S.C. 135 et seq., 136-136y; 15 U.S.C. 2001, 2003, 
2005, 2006, 2601-2671; 21 U.S.C. 331j, 346a; 31 U.S.C. 9701; 33 
U.S.C. 1251 et seq., 1311, 1313d, 1314, 1318, 1321, 1326, 1330, 
1342, 1344, 1345 (d) and (e), 1361; E.O. 11735, 38 FR 21243, 3 CFR, 
1971-1975 Comp. p. 973; 42 U.S.C. 241, 242b, 243, 246, 300f, 300g, 
300g-1, 300g-2, 300g-3, 300g-4, 300g-5, 300g-6, 300j-1, 300j-2, 
300j-3, 300j-4, 300j-9, 1857 et seq., 6901-6992k, 7401-7671q, 7542, 
9601-9657, 11023, 11048.


0
2. Amend the table in Sec.  9.1 by adding entries for Sec. Sec.  
721.11863 through 721.11893 in numerical order under the undesignated 
center heading ``Significant New Uses of Chemical Substances'' to read 
as follows:


Sec.  9.1  OMB approvals under the Paperwork Reduction Act.

* * * * *

------------------------------------------------------------------------
                   40 CFR citation                      OMB control No.
------------------------------------------------------------------------
 
                                * * * * *
               Significant New Uses of Chemical Substances
------------------------------------------------------------------------
 
                                * * * * *
721.11863...........................................           2070-0038
721.11864...........................................           2070-0038
721.11865...........................................           2070-0038
721.11866...........................................           2070-0038
721.11867...........................................           2070-0038
721.11868...........................................           2070-0038
721.11869...........................................           2070-0038
721.11870...........................................           2070-0038
721.11871...........................................           2070-0038
721.11872...........................................           2070-0038
721.11873...........................................           2070-0038
721.11874...........................................           2070-0038
721.11875...........................................           2070-0038
721.11876...........................................           2070-0038
721.11877...........................................           2070-0038
721.11878...........................................           2070-0038
721.11879...........................................           2070-0038
721.11880...........................................           2070-0038
721.11881...........................................           2070-0038
721.11882...........................................           2070-0038
721.11883...........................................           2070-0038
721.11884...........................................           2070-0038
721.11885...........................................           2070-0038
721.11886...........................................           2070-0038
721.11887...........................................           2070-0038
721.11888...........................................           2070-0038
721.11889...........................................           2070-0038
721.11890...........................................           2070-0038
721.11891...........................................           2070-0038
721.11892...........................................           2070-0038
721.11893...........................................           2070-0038
 
                                * * * * *
------------------------------------------------------------------------

* * * * *

PART 721--SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES

0
3. The authority citation for part 721 continues to read as follows:

    Authority: 15 U.S.C. 2604, 2607, and 2625(c).


0
4. Add Sec. Sec.  721.11863 through 721.11893 to subpart E to read as 
follows:

[[Page 100366]]

Sec.
* * * * *
721.11863 1,2-Ethanediamine, N-(1-methylethyl)-N-[2-[(1-
methylethyl)amino]ethyl]-.
721.11864 Fatty acids, polymers with substituted carbomonocycles, 
dialkanolamine, alkyl substituted alkanediamine and halo-substituted 
heteromonocycle, formates (salts) (generic).
721.11865 Alkanesulfonic acid, 2-[(2-aminoethyl)heteroatom-
substituted]-, sodium salt (1:1), polymer with .alpha.-[2,2-
bis(hydroxymethyl)butyl]-.omega.-methoxypoly(oxy-1,2-ethanediyl) and 
1,1'-methylenebis[4-isocyanatocyclohexane], acrylic acid-
dipenthaerythritol reaction products- and polypropylene glycol ether 
with pentaerythritol (4:1) triacrylate-blocked (generic).
721.11866 Alkanoic acid, hydroxy-(hydroxyalkyl)-alkyl-, polymer with 
.alpha.-[(hydroxyalkyl)alkyl]-.omega.-alkoxypoly(oxy-alkanediyl), 
(haloalkyl)oxiane polymer (alkylalkylidene)bis[hydroxy-
carbomonocycle] alkenoate and isocyanate-alkyl-carbomonocycle, 
hydroxyalkyl acrylate-blocked (generic).
721.11867 1,4-Benzenedicarboxylic acid, bis[2-(2-butoxyethoxy)ethyl] 
ester (9CI).
721.11868 Isocyanic acid, polyalkylenepolyarylene ester, polymer 
with alkyl-hydroxyalkyl-alkanediol, alkoxyalcohol and 
alkoxylalkoxyalcohol-blocked (generic).
721.11869 Substituted alkanoic acid, compound with aminoalkylalkyl-
aminoalkylalkoxy-polyoxyalkylalkanediyl, polymer with haloalkyl-
epoxide and alkylalkylidene-cycloarylalcohol (generic).
721.11870 Bisphenol A epichlorohydrin polymer with alkylpolyalkene-
polyarylene-hydroxypolyoxyalkyldiyl reaction products with 
alkylalkylidenealkylalkylidene-aminoalkyl-alkanepolyamine and 
alkylaminoalkanol (generic).
721.11871 Sulfur based acid, compds. with modified bisphenol A-
epichlorohydrin-polyalkylene polyol ether with bisphenol A polymer-
N-dialkylalkylidene-N- (dialkylalklyidene)aminoalkyl-
alkanepolyamine-alkylaminoalkanol reaction products (generic).
721.11872 1,2-Alkanediol, 3-aryloxy, mono phosphate ester (generic).
721.11873 Metalloxanes, alkyl, alkyl group-terminated, reaction 
products with dihalo-dialkylalkylaryl-alkyl-polycyclic-
ylidene(dialkylsilylene)-dialkylalkylaryl-alkylalkyl-polycyclic-
ylidene, metal oxide and nonmetallic oxide (generic).
721.11874 Alkenoic acid, reaction products with pentaerythritol, 
polymers with diisocyanatoalkane and heteromonocyle homopolymer 
esters with alkanoic acid-pentaerythritol reaction products 
(generic).
721.11875 Carbopolycycle octa-alkene, halo (generic).
721.11876 2-Propenoic acid, (polyhydro-1,3-dioxo-2H-isoindol-2-
yl)alkyl ester (generic).
721.11877 Heteromonocycle, polymer, [2-[(1-oxo-2-propen-1-
yl)oxy]alkyl]ester (generic).
721.11878 Hydrocarbons linear and branched, light alkylate 
(generic).
721.11879 Hydrocarbons linear and branched, light catalytic cracked 
(generic).
721.11880 Hydrocarbons linear and branched, heavy catalytic cracked 
(generic).
721.11881 Hydrocarbons linear and branched, light hydrocracked 
(generic).
721.11882 Hydrocarbons linear and branched, isomerization (generic).
721.11883 Hydrocarbons linear and branched, heavy catalytic reformed 
(generic).
721.11884 Hydrocarbons linear and branched, hydrotreated light 
(generic).
721.11885 Hydrocarbons linear and branched, hydrotreated light 
paraffinic (generic).
721.11886 Hydrocarbons linear and branched, light catalytic cracked 
(generic).
721.11887 Hydrocarbons linear and branched, heavy hydrocracked 
(generic).
721.11888 Hydrocarbons linear and branched, heavy catalytic cracked 
(generic).
721.11889 Hydrocarbons linear and branched, heavy hydrocracked 
(generic).
721.11890 Hydrocarbons linear and branched, light hydrocracked 
(generic).
721.11891 Imidazole-carboxylic acid, substituted (generic).
721.11892 Multi-walled carbon nanotubes (generic).
721.11893 Multi-walled carbon nanotubes (generic).
* * * * *


Sec.  721.11863  1,2-Ethanediamine, N-(1-methylethyl)-N-[2-[(1-
methylethyl)amino]ethyl]-.

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,2-ethanediamine, 
N-(1-methylethyl)-N-[2-[(1-methylethyl) amino]ethyl]- (PMN P-18-398; 
CASRN 10507-06-9) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: acute toxicity; specific 
target organ toxicity; reproductive toxicity; skin corrosion; serious 
eye damage; skin sensitization. For purposes of Sec.  721.72(g)(3), 
this substance may be: toxic to aquatic life. Alternative hazard and 
warning statements that meet the criteria of the Globally Harmonized 
System and OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(k).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11864  Fatty acids, polymers with substituted 
carbomonocycles, dialkanolamine, alkyl substituted alkanediamine and 
halo-substituted heteromonocycle, formates (salts) (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as fatty 
acids, polymers with substituted carbomonocycles, dialkanolamine, alkyl 
substituted alkanediamine and halo-substituted heteromonocycle, 
formates (salts) (PMN P-19-49) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted 
(cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes

[[Page 100367]]

of Sec.  721.63(b), the concentration is set at 1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1), (3), and (5). For purposes of Sec.  
721.72(e), the concentration is set at 1%. For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; reproductive toxicity; specific organ toxicity. For 
purposes of Sec.  721.72(g)(3), this substance may be: toxic to aquatic 
life. Alternative hazard and warning statements that meet the criteria 
of the Globally Harmonized System and OSHA Hazard Communication 
Standard may be used.
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture or process the substance in any 
manner that generates a vapor, mist, or aerosol. It is a significant 
new use to use the substance in any manner that generates a vapor, 
mist, or aerosol that results in inhalation to industrial or commercial 
workers. It is a significant new use to manufacture the substance to 
contain the confidential residual identified in the TSCA Order for this 
substance at greater than 0.1%.
    (iv) Release to Water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N=114.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11865  Alkanesulfonic acid, 2-[(2-aminoethyl)heteroatom-
substituted]-, sodium salt (1:1), polymer with .alpha.-[2,2-
bis(hydroxymethyl)butyl]-.omega.-methoxypoly(oxy-1,2-ethanediyl) and 
1,1'-methylenebis[4-isocyanatocyclohexane], acrylic acid-
dipenthaerythritol reaction products- and polypropylene glycol ether 
with pentaerythritol (4:1) triacrylate-blocked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkanesulfonic acid, 2-[(2-aminoethyl)heteroatom-substituted]-, sodium 
salt (1:1), polymer with .alpha.-[2,2-bis(hydroxymethyl)butyl]-.omega.-
methoxypoly(oxy-1,2-ethanediyl) and 1,1'-methylenebis[4-
isocyanatocyclohexane], acrylic acid-dipenthaerythritol reaction 
products- and polypropylene glycol ether with pentaerythritol (4:1) 
triacrylate-blocked (PMN P-19-160) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c).
    When determining which persons are reasonably likely to be exposed 
as required for Sec.  721.63(a)(1), engineering control measures (e.g., 
enclosure or confinement of the operation, general and local 
ventilation) or administrative control measures (e.g., workplace 
policies and procedures) shall be considered and implemented to prevent 
exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1) and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; serious eye damage; skin sensitization; respiratory 
sensitization; reproductive toxicity; specific organ toxicity. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure.
    (iv) Release to Water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N=302.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11866  Alkanoic acid, hydroxy-(hydroxyalkyl)-alkyl-, polymer 
with .alpha.-[(hydroxyalkyl)alkyl]-.omega.-alkoxypoly(oxy-alkanediyl), 
(haloalkyl)oxiane polymer (alkylalkylidene)bis[hydroxy-carbomonocycle] 
alkenoate and isocyanate-alkyl-carbomonocycle, hydroxyalkyl acrylate-
blocked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance generically identified as 
alkanoic acid, hydroxy-(hydroxyalkyl)-alkyl-, polymer with .alpha.-
[(hydroxyalkyl)alkyl]-.omega.-alkoxypoly(oxy-alkanediyl), 
(haloalkyl)oxiane polymer (alkylalkylidene)bis[hydroxy-carbomonocycle] 
alkenoate and isocyanate-alkyl-carbomonocycle, hydroxyalkyl acrylate-
blocked (PMN P-20-101) is subject to reporting under this section for 
the significant new uses described in paragraph (a)(2) of this section. 
The requirements of this section do not apply to quantities of the 
substance after they have been completely cured.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: acute toxicity; skin 
irritation; eye irritation; respiratory sensitization; skin 
sensitization; reproductive toxicity; specific target organ toxicity. 
For purposes of Sec.  721.72(g)(3), this substance may be: toxic to 
aquatic life. Alternative hazard and warning statements that meet the 
criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture or process the substance with greater than 20% (by weight) 
oligomer content below 1,000 daltons (i.e., low molecular weight 
species). It is a significant new use to use the substance in a manual 
spray application.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The

[[Page 100368]]

provisions of Sec.  721.185 apply to this section.


Sec.  721.11867  1,4-Benzenedicarboxylic acid, bis[2-(2-
butoxyethoxy)ethyl] ester (9CI).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified as 1,4-
benzenedicarboxylic acid, bis[2-(2-butoxyethoxy)ethyl] ester (9CI) (PMN 
P-20-182; CASRN 90430-63-0) is subject to reporting under this section 
for the significant new uses described in paragraph (a)(2) of this 
section. The requirements of this section do not apply to quantities of 
the substance after they have been completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 1,000.
    (A) As an alternative to the respirator requirements in paragraph 
(a)(2)(i) of this section, a manufacturer or processor may choose to 
follow the new chemical exposure limit (NCEL) provision listed in the 
TSCA section 5(e) Order for this substance. The NCEL is 0.01 mg/m\3\ as 
an 8-hour time weighted average. Persons who wish to pursue NCELs as an 
alternative to Sec.  721.63 respirator requirements may request to do 
so under Sec.  721.30. Persons whose Sec.  721.30 requests to use the 
NCELs approach are approved by EPA will be required to follow NCELs 
provisions comparable to those contained in the corresponding TSCA 
section 5(e) Order.
    (B) [Reserved]
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: skin sensitization; 
reproductive toxicity; specific target organ toxicity. For purposes of 
Sec.  721.72(g)(3), this substance may be: toxic to aquatic life. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N=4.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (h) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11868  Isocyanic acid, polyalkylenepolyarylene ester, polymer 
with alkyl-hydroxyalkyl-alkanediol, alkoxyalcohol and 
alkoxylalkoxyalcohol-blocked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
isocyanic acid, polyalkylenepolyarylene ester, polymer with alkyl-
hydroxyalkyl-alkanediol, alkoxyalcohol and alkoxylalkoxyalcohol-blocked 
(PMN P-21-56) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section. The 
requirements of this section do not apply to quantities of the 
substance after they have been completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5), (b), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50 or 1,000 if spray 
applied. For purposes of Sec.  721.63(b), the concentration is set at 
1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1) and (5). For purposes of Sec.  
721.72(e), the concentration is set at 1%. For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity. Alternative 
hazard and warning statements that meet the criteria of the Globally 
Harmonized System and OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11869  Substituted alkanoic acid, compound with 
aminoalkylalkyl-aminoalkylalkoxy-polyoxyalkylalkanediyl, polymer with 
haloalkyl-epoxide and alkylalkylidene-cycloarylalcohol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
substituted alkanoic acid, compound with aminoalkylalkyl-
aminoalkylalkoxy-polyoxyalkylalkanediyl, polymer with haloalkyl-epoxide 
and alkylalkylidene-cycloarylalcohol (PMN P-21-58) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1), (3), and (5). For purposes of Sec.  
721.72(e), the concentration is set at 1%. For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; specific target organ toxicity. For purposes of Sec.  
721.72(g)(3), this substance may be: toxic to aquatic life. Alternative 
hazard and warning statements that meet the criteria of the Globally 
Harmonized System and OSHA Hazard Communication Standard may be used.

[[Page 100369]]

    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 50.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11870  Bisphenol A epichlorohydrin polymer with 
alkylpolyalkene-polyarylene-hydroxypolyoxyalkyldiyl reaction products 
with alkylalkylidenealkylalkylidene-aminoalkyl-alkanepolyamine and 
alkylaminoalkanol (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
bisphenol A epichlorohydrin polymer with alkylpolyalkene-polyarylene-
hydroxypolyoxyalkyldiyl reaction products with 
alkylalkylidenealkylalkylidene-aminoalkyl-alkanepolyamine and 
alkylaminoalkanol (PMN P-21-60) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted 
(cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1), (3), and (5). For purposes of Sec.  
721.72(e), the concentration is set at 0.1%. For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; carcinogenicity; reproductive toxicity; specific target 
organ toxicity. For purposes of Sec.  721.72(g)(3), this substance may 
be: toxic to aquatic life. Alternative hazard and warning statements 
that meet the criteria of the Globally Harmonized System and OSHA 
Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.118671  Sulfur based acid, compds. with modified bisphenol A-
epichlorohydrin-polyalkylene polyol ether with bisphenol A polymer-N-
dialkylalkylidene-N- (dialkylalklyidene)aminoalkyl-alkanepolyamine-
alkylaminoalkanol reaction products (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as sulfur 
based acid, compds. with modified bisphenol A-epichlorohydrin-
polyalkylene polyol ether with bisphenol A polymer-N-dialkylalkylidene-
N-(dialkylalklyidene)aminoalkyl-alkanepolyamine-alkylaminoalkanol 
reaction products (PMN P-21-61) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted 
(cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1), (3), and (5). For purposes of Sec.  
721.72(e), the concentration is set at 0.1%. For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; carcinogenicity; reproductive toxicity; specific target 
organ toxicity. For purposes of Sec.  721.72(g)(3), this substance may 
be: toxic to aquatic life. Alternative hazard and warning statements 
that meet the criteria of the Globally Harmonized System and OSHA 
Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 11.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11872  1,2-Alkanediol, 3-aryloxy, mono phosphate ester 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 1,2-
alkanediol, 3-aryloxy, mono phosphate ester (PMN P-21-66) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
completely destroyed.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general

[[Page 100370]]

and local ventilation) or administrative control measures (e.g., 
workplace policies and procedures) shall be considered and implemented 
to prevent exposure, where feasible. For purposes of Sec.  721.63(b), 
the concentration is set at 1.0%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1), (3), and (5). For the purposes of 
Sec.  721.72(e), the concentration is set at 1.0%. For purposes of 
Sec.  721.72(g)(1), this substance may cause: acute toxicity; skin 
corrosion; skin irritation; serious eye damage; eye irritation; 
reproductive toxicity; specific target organ toxicity. For purposes of 
Sec.  721.72(g)(3), this substance may be: toxic to aquatic life. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to 
manufacture, process, or use the substance in any manner that results 
in inhalation exposure or that results in fugitive air emissions. It is 
a significant new use to use the substance other than as an epoxy 
curative.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11873  Metalloxanes, alkyl, alkyl group-terminated, reaction 
products with dihalo-dialkylalkylaryl-alkyl-polycyclic-
ylidene(dialkylsilylene)-dialkylalkylaryl-alkylalkyl-polycyclic-
ylidene, metal oxide and nonmetallic oxide (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
metalloxanes, alkyl, alkyl group-terminated, reaction products with 
dihalo-dialkylalkylaryl-alkyl-polycyclic-ylidene(dialkylsilylene)-
dialkylalkylaryl-alkylalkyl-polycyclic-ylidene, metal oxide and 
nonmetallic oxide (PMN P-21-68) is subject to reporting under this 
section for the significant new uses described in paragraph (a)(2) of 
this section.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1) and (5). For purposes of Sec.  
721.72(g)(1), this substance may cause: acute toxicity; skin corrosion; 
skin irritation; serious eye damage; eye irritation; respiratory 
sensitization; skin sensitization; germ cell mutagenicity; reproductive 
toxicity; specific target organ toxicity. Alternative hazard and 
warning statements that meet the criteria of the Globally Harmonized 
System and OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(a) through (c). It is a significant new 
use to manufacture, process, or use the substance in any manner that 
results in inhalation or dermal exposure.
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 50.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i), and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11874  Alkenoic acid, reaction products with pentaerythritol, 
polymers with diisocyanatoalkane and heteromonocyle homopolymer esters 
with alkanoic acid-pentaerythritol reaction products (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
alkenoic acid, reaction products with pentaerythritol, polymers with 
diisocyanatoalkane and heteromonocyle homopolymer esters with alkanoic 
acid-pentaerythritol reaction products (PMN P-21-83) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 1,000.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3) and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; respiratory sensitization; skin sensitization; specific 
target organ toxicity. For purposes of Sec.  721.72(g)(3), this 
substance may be: toxic to aquatic life. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o).
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 1.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11875  Carbopolycycle octa-alkene, halo (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
carbopolycycle octa-alkene, halo (PMN P-21-84) is subject to reporting 
under this section for the significant new uses described in paragraph 
(a)(2) of this section.

[[Page 100371]]

    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: acute toxicity; skin 
corrosion; serious eye damage; skin sensitization; genetic toxicity. 
For purposes of Sec.  721.72(g)(3), this substance may be: toxic to 
aquatic life. Alternative hazard and warning statements that meet the 
criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 7.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (h) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11876  2-Propenoic acid, (polyhydro-1,3-dioxo-2H-isoindol-2-
yl)alkyl ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 2-
propenoic acid, (polyhydro-1,3-dioxo-2H-isoindol-2-yl)alkyl ester (PMN 
P-21-92) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section. The 
requirements of this section do not apply to quantities of the PMN 
substance after they have been completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5), (b), and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(b), the concentration is 
set at 1.0%. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (f) and (g)(1) and (3). For purposes of Sec.  
721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; specific target organ toxicity; reproductive toxicity. For 
purposes of Sec.  721.72(g)(3), this substance may be: toxic to aquatic 
life. For purposes of Sec.  721.72(e), the concentration is set at 
1.0%. Alternative hazard and warning statements that meet the criteria 
of the Globally Harmonized System and OSHA Hazard Communication 
Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o). It is a significant new use to use the 
substance at a concentration of greater than 40% in formulation when 
inhalation exposure is expected.
    (iv) Disposal. It is a significant new use to dispose of the 
substance or waste streams containing the substance other than by 
incineration or RCRA subtitle C landfill.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11877  Heteromonocycle, polymer, [2-[(1-oxo-2-propen-1-
yl)oxy]alkyl]ester (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
heteromonocycle, polymer, [2-[(1-oxo-2-propen-1-yl)oxy]alkyl]ester (PMN 
P-21-102) is subject to reporting under this section for the 
significant new uses described in paragraph (a)(2) of this section. The 
requirements of this section do not apply to quantities of the 
substance after they have been completely reacted (cured).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 10.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: skin irritation; eye 
irritation; specific target organ toxicity; developmental toxicity; 
skin sensitization. For purposes of Sec.  721.72(g)(3), this substance 
may be: toxic to aquatic life. Alternative hazard and warning 
statements that meet the criteria of the Globally Harmonized System and 
OSHA Hazard Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(o).
    (iv) Release to water. Requirements as specified in Sec.  
721.90(a)(4), (b)(4), and (c)(4), where N = 337.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) and (k) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11878  Hydrocarbons linear and branched, light alkylate 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, light alkylate (PMN P-21-

[[Page 100372]]

109) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section. The requirements of 
this section do not apply to quantities of the substance after they 
have been incorporated into a fuel, fuel additive, fuel blending stock, 
or used as a refinery feedstock (including, but not limited to 
cracking, coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11879  Hydrocarbons linear and branched, light catalytic 
cracked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, light catalytic cracked (PMN P-21-
110) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section. The requirements of 
this section do not apply to quantities of the substance after they 
have been incorporated into a fuel, fuel additive, fuel blending stock, 
or used as a refinery feedstock (including, but not limited to 
cracking, coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11880  Hydrocarbons linear and branched, heavy catalytic 
cracked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, heavy catalytic cracked (PMN P-21-
111) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section. The requirements of 
this section do not apply to quantities of the substance after they 
have been incorporated into a fuel, fuel additive, fuel blending stock, 
or used as a refinery feedstock (including, but not limited to 
cracking, coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11881  Hydrocarbons linear and branched, light hydrocracked 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, light hydrocracked (PMN P-21-112) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into a fuel, fuel additive, fuel blending stock, or 
used as a refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent

[[Page 100373]]

exposure, where feasible. For purposes of Sec.  721.63(b), the 
concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through(i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11882  Hydrocarbons linear and branched, isomerization 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, isomerization (PMN P-21-113) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into a fuel, fuel additive, fuel blending stock, or 
used as a refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11883  Hydrocarbons linear and branched, heavy catalytic 
reformed (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, heavy catalytic reformed (PMN P-21-
114) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section. The requirements of 
this section do not apply to quantities of the substance after they 
have been incorporated into a fuel, fuel additive, fuel blending stock, 
or used as a refinery feedstock (including, but not limited to 
cracking, coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11884  Hydrocarbons linear and branched, hydrotreated light 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, hydrotreated light (PMN P-21-116) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into a fuel, fuel additive, fuel blending stock, or 
used as a refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in

[[Page 100374]]

Sec.  721.125(a) through (i) are applicable to manufacturers, 
importers, and processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11885  Hydrocarbons linear and branched, hydrotreated light 
paraffinic (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, hydrotreated light paraffinic (PMN P-
21-117) is subject to reporting under this section for the significant 
new uses described in paragraph (a)(2) of this section. The 
requirements of this section do not apply to quantities of the 
substance after they have been incorporated into a fuel, fuel additive, 
fuel blending stock, or used as a refinery feedstock (including, but 
not limited to cracking, coking, hydroprocessing, distillation, or 
deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11886  Hydrocarbons linear and branched, light catalytic 
cracked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance generically identified as 
hydrocarbons linear and branched, light catalytic cracked (PMN P-21-
118) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section. The requirements of 
this section do not apply to quantities of the substance after they 
have been incorporated into a fuel, fuel additive, fuel blending stock, 
or used as a refinery feedstock (including, but not limited to 
cracking, coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11887  Hydrocarbons linear and branched, heavy hydrocracked 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, heavy hydrocracked (PMN P-21-119) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into a fuel, fuel additive, fuel blending stock, or 
used as a refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11888  Hydrocarbons linear and branched, heavy catalytic 
cracked (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, heavy catalytic cracked (PMN P-21-
121) is subject to reporting under this section for the significant new 
uses described in paragraph (a)(2) of this section. The requirements of 
this section do not apply to quantities of the substance after they 
have been incorporated into a fuel, fuel additive, fuel blending stock, 
or used as a refinery feedstock (including, but not limited to

[[Page 100375]]

cracking, coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11889  Hydrocarbons linear and branched, heavy hydrocracked 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, heavy hydrocracked (PMN P-21-122) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into a fuel, fuel additive, fuel blending stock, or 
used as a refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11890  Hydrocarbons linear and branched, light hydrocracked 
(generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
hydrocarbons linear and branched, light hydrocracked (PMN P-21-123) is 
subject to reporting under this section for the significant new uses 
described in paragraph (a)(2) of this section. The requirements of this 
section do not apply to quantities of the substance after they have 
been incorporated into a fuel, fuel additive, fuel blending stock, or 
used as a refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting).
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3), (b), and (c). When determining which persons are 
reasonably likely to be exposed as required for Sec.  721.63(a)(1), 
engineering control measures (e.g., enclosure or confinement of the 
operation, general and local ventilation) or administrative control 
measures (e.g., workplace policies and procedures) shall be considered 
and implemented to prevent exposure, where feasible. For purposes of 
Sec.  721.63(b), the concentration is set at 0.1%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a).
    (iii) Industrial, commercial, and consumer activities. It is a 
significant new use to manufacture, process, or use the substance other 
than for processing and use as a fuel, fuel additive, fuel blending 
stock, or refinery feedstock (including, but not limited to cracking, 
coking, hydroprocessing, distillation, or deasphalting) subject to 40 
CFR part 79 or 1090.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (i) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11891  Imidazole-carboxylic acid, substituted (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as 
imidazole-carboxylic acid, substituted (P-21-197) is subject to 
reporting under this section for the significant new uses described in 
paragraph (a)(2) of this section. The requirements of this section do 
not apply to quantities of the substance after they have been 
incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 50.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3) and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: acute toxicity; skin 
corrosion; eye irritation; serious eye damage; skin sensitization;

[[Page 100376]]

reproductive toxicity; specific target organ toxicity. For purposes of 
Sec.  721.72(g)(3) this substance may be: toxic to aquatic life. 
Alternative hazard and warning statements that meet the criteria of the 
Globally Harmonized System and OSHA Hazard Communication Standard may 
be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f). It is a significant new use to process 
or use the substance other than in an enclosed process, except that 
sampling and equipment cleaning operations need not occur in an 
enclosed process.
    (iv) Disposal. It is a significant new use to dispose of the 
substance or waste streams containing the substance other than by 
incineration with 99.9% efficiency.
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (j) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11892  Multi-walled carbon nanotubes (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as multi-
walled carbon nanotubes (PMN P-21-216) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted 
(cured), entrained in a polymer, or incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 1,000 if the capture and 
reduction rate is at least 99.5% but not 99.975% or greater, or at 
least 50 if the capture and reduction rate is at least 99.975%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: eye irritation; skin 
irritation; respiratory sensitization; skin sensitization; genetic 
toxicity; reproductive toxicity; carcinogenicity; specific target organ 
toxicity. For purposes of Sec.  721.72(g)(3), this substance may be: 
toxic to aquatic life. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f). It is a significant new use to 
manufacture the substance to contain the confidential impurity listed 
in the Order at greater than 1% (by weight). It is a significant new 
use to process or use the substance other than for the confidential use 
allowed in the Order. It is a significant new use to process or use the 
substance other than in application methods that do not generate a 
vapor, mist, dust, or aerosol, unless such application method occurs in 
an enclosed process.
    (iv) Disposal. Requirements as specified in Sec.  721.85 (a)(1) and 
(2), (b)(1) and (2), and (c)(1) and (2). It is a significant new use to 
release the substance directly, whether by point (stack) or non-point 
(fugitive) sources, to air.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).
    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.


Sec.  721.11893  Multi-walled carbon nanotubes (generic).

    (a) Chemical substance and significant new uses subject to 
reporting. (1) The chemical substance identified generically as multi-
walled carbon nanotubes (PMN P-21-217) is subject to reporting under 
this section for the significant new uses described in paragraph (a)(2) 
of this section. The requirements of this section do not apply to 
quantities of the substance after they have been completely reacted 
(cured), entrained in a polymer, or incorporated into an article.
    (2) The significant new uses are:
    (i) Protection in the workplace. Requirements as specified in Sec.  
721.63(a)(1) and (3) through (5) and (c). When determining which 
persons are reasonably likely to be exposed as required for Sec.  
721.63(a)(1) and (4), engineering control measures (e.g., enclosure or 
confinement of the operation, general and local ventilation) or 
administrative control measures (e.g., workplace policies and 
procedures) shall be considered and implemented to prevent exposure, 
where feasible. For purposes of Sec.  721.63(a)(5), respirators must 
provide a National Institute for Occupational Safety and Health (NIOSH) 
assigned protection factor (APF) of at least 1,000 if the capture and 
reduction rate is at least 99.5% but not 99.975% or greater or of at 
least 50 if the capture and reduction rate is at least 99.975%.
    (ii) Hazard communication. Requirements as specified in Sec.  
721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of 
Sec.  721.72(g)(1), this substance may cause: eye irritation; skin 
irritation; respiratory sensitization; skin sensitization; genetic 
toxicity; reproductive toxicity; carcinogenicity; specific target organ 
toxicity. For purposes of Sec.  721.72(g)(3), this substance may be: 
toxic to aquatic life. Alternative hazard and warning statements that 
meet the criteria of the Globally Harmonized System and OSHA Hazard 
Communication Standard may be used.
    (iii) Industrial, commercial, and consumer activities. Requirements 
as specified in Sec.  721.80(f). It is a significant new use to 
manufacture the substance to contain the confidential impurity listed 
in the Order at greater than 1% (by weight). It is a significant new 
use to process or use the substance other than for the confidential use 
allowed in the Order. It is a significant new use to process or use the 
substance other than in application methods that do not generate a 
vapor, mist, dust, or aerosol, unless such application method occurs in 
an enclosed process.
    (iv) Disposal. Requirements as specified in Sec.  721.85 (a)(1) and 
(2), (b)(1) and (2), and (c)(1) and (2). It is a significant new use to 
release the substance directly, either by point (stack) or non-point 
(fugitive) sources, to air.
    (v) Release to water. Requirements as specified in Sec.  
721.90(a)(1), (b)(1), and (c)(1).

[[Page 100377]]

    (b) Specific requirements. The provisions of subpart A of this part 
apply to this section except as modified by this paragraph (b).
    (1) Recordkeeping. Recordkeeping requirements as specified in Sec.  
721.125(a) through (k) are applicable to manufacturers, importers, and 
processors of this substance.
    (2) Limitation or revocation of certain notification requirements. 
The provisions of Sec.  721.185 apply to this section.
* * * * *
[FR Doc. 2024-29276 Filed 12-11-24; 8:45 am]
BILLING CODE 6560-50-P`