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 Environmental Protection Agency 40 CFR Parts 9 and 721
[EPA-HQ-OPPT-2022-0771; FRL-11912-02-OCSPP]
RIN 2070-AB27
 AGENCY: Environmental Protection Agency (EPA).
 ACTION: Final rule.
 SUMMARY: EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for certain chemical substances that were 
                        ( print page 100362)
                        the subject of premanufacture notices (PMNs) and are also subject to an Order issued by EPA pursuant to TSCA. The SNURs require persons to notify EPA at least 90 days before commencing the manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use in the SNUR. The required notification initiates EPA's evaluation of the conditions of that use for that chemical substance. In addition, the manufacture or processing for the significant new use may not commence until EPA has conducted a review of the required notification; made an appropriate determination regarding that notification; and taken such actions as required by that determination.
 DATES: This rule is effective February 10, 2025. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EST) on December 26, 2024.
 ADDRESSES: The docket for this action, identified under docket identification (ID) number EPA-HQ-OPPT-2022-0771, is available online at 
                        *https://www.regulations.gov*
                         or in person at the Office of Pollution Prevention and Toxics Docket (OPPT Docket) in the Environmental Protection Agency Docket Center (EPA/DC). Please review the visitor instructions and additional information about the docket available at 
                        *https://www.epa.gov/​dockets.*
 FOR FURTHER INFORMATION CONTACT: *For technical information:*
                         Jennise Armstead, New Chemicals Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: (202) 566-1486; email address: 
                        *armstead.jennise@epa.gov.* *For general information on SNURs:*
                         William Wysong, New Chemicals Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460-0001; telephone number: (202) 564-4163; email address: 
                        *wysong.william@epa.gov.* *For general information on TSCA:*
                         The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; email address: 
                        *TSCA-Hotline@epa.gov.*


SUPPLEMENTARY INFORMATION: I. Executive Summary A. What is the Agency's authority for taking this action? TSCA section 5(a)(2) (15 U.S.C. 2604(a)(2)) authorizes EPA to determine that a use of a chemical substance is a “significant new use.” EPA must make this determination by rule after considering all relevant factors, including the factors in TSCA section 5(a)(2). B. What action is the Agency taking? EPA is finalizing SNURs under TSCA section 5(a)(2) for the chemical substances identified in Unit III. These chemical substances were the subject of PMNs and are also subject to an Order issued by EPA pursuant to TSCA section 5(e)(1)(A), as required by the determinations made under TSCA section 5(a)(3)(B). The SNURs identify as significant new uses any manufacturing, processing, use, distribution in commerce, or disposal that does not conform to the restrictions imposed by the underlying TSCA Orders, consistent with TSCA section 5(f)(4). The SNURs require persons who intend to manufacture or process any of these chemical substances for an activity that is designated as a significant new use in the SNURs to notify EPA at least 90 days before commencing that activity. Previously, EPA proposed SNURs for these chemical substances in the 
                    **Federal Register**
                     of June 11, 2024 (89 FR 49121 (FRL-11912-01-OCSPP)). The docket includes information considered by the Agency in developing the proposed and final rules, including public comments and EPA's responses to the comments received as discussed in Unit II.E. C. Does this action apply to me? 1. General Applicability This action applies to you if you manufacture, process, or use the chemical substances identified in Unit III. The following list of North American Industrial Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers determine whether this document applies to them. Potentially affected entities may include: Manufacturers or processors of one or more subject chemical substances (NAICS codes 325 and 324110),*e.g.,*
                     chemical manufacturing and petroleum refineries. 2. Applicability to Importers and Exporters This action may also apply to certain entities through pre-existing import certification and export notification requirements under TSCA (
                    *https://www.epa.gov/​tsca-import-export-requirements*). Chemical importers are subject to TSCA section 13 (15 U.S.C. 2612), the requirements in 19 CFR 12.118 through 12.127, 19 CFR 127.28, and 40 CFR part 707, subpart B. Chemical importers must certify that the shipment of the chemical substance complies with all applicable rules and orders under TSCA, including regulations issued under TSCA sections 5, 6, 7 and Title IV. Pursuant to 40 CFR 721.20, any persons who export or intend to export a chemical substance identified in Unit III. are subject to the export notification provisions of TSCA section 12(b) (15 U.S.C. 2611(b)) and must comply with the export notification requirements in 40 CFR part 707, subpart D. D. What are the incremental economic impacts of this action? EPA has evaluated the potential costs of establishing SNUN reporting requirements for potential manufacturers and processors of the chemical substances identified in Unit III. This analysis, which is available in the docket, is briefly summarized here. 1. Estimated Costs for SNUN Submissions A SNUR requires that any person who intends to engage in such activity in the future must first notify EPA by submitting a SNUN. If a SNUN is submitted, costs are an estimated $45,000 per SNUN submission for large business submitters and $14,500 for small business submitters. These estimates include the cost to prepare and submit the SNUN (including registration for EPA's Central Data Exchange (CDX)), and the payment of a user fee. Businesses that submit a SNUN would be subject to either a $37,000 user fee required by 40 CFR 700.45(c)(2)(ii) and (d), or, if they are a small business as defined at 13 CFR 121.201, a reduced user fee of $6,480 (40 CFR 700.45(c)(1)(ii) and (d)). These estimates reflect the costs and fees as they are known at the time of this rulemaking. 2. Estimated Costs for Export Notifications EPA has also evaluated the potential costs associated with the pre-existing export notification requirements under TSCA section 12(b) and the implementing regulations at 40 CFR part 707, subpart D. For persons exporting a substance that is the subject of a SNUR, a one-time notice to EPA must be provided for the first export or intended export to a particular country. The total costs of export notification will vary by chemical, depending on the number of required notifications (
                    *i.e.,*
                     the number of countries to which the chemical is 
                    ( print page 100363)
                    exported). While EPA is unable to make any estimate of the likely number of export notifications for the chemical substances covered by these SNURs, as stated in the accompanying economic analysis, the estimated cost of the export notification requirement on a per unit basis is approximately $106. II. Background A. General Information About SNURS Unit II. of the proposed rule provides general information about SNURs, and additional information about EPA's new chemical program is available at 
                    *https://www.epa.gov/​reviewing-new-chemicals-under-toxic-substances-control-act-tsca.* B. Applicability of the Significant New Use Designation To establish a significant new use, EPA must determine that the use is not ongoing. As discussed in Unit II.E. of the proposed rule, EPA concluded that the proposed significant new uses were not ongoing. If EPA subsequently determines that such a use was ongoing as of the date of publication of the proposed rule and did not cease prior to issuance of the final rule, EPA will not designate that use as a significant new use in the final rule. EPA has no information to suggest that any of the significant new uses identified in this rule are ongoing. As discussed in the 
                    **Federal Register**
                     of April 24, 1990 (55 FR 17376 (FRL-3658-5)), EPA has decided that the intent of TSCA section 5(a)(1)(B) is best served by designating a use as a significant new use as of the date of publication of the proposed rule rather than as of the effective date of the final rule. The objective of EPA's approach is to ensure that a person cannot impede finalization of a SNUR by initiating a significant new use after publication of the proposed rule but before the effective date of the final rule. Uses arising after the publication of the proposed rule are distinguished from uses that are identified in the final rule as having been ongoing on the date of publication of the proposed rule. The former would be new uses, the latter ongoing uses, except that uses that are identified as ongoing as of the publication of the proposed rule would not be considered ongoing uses if they have ceased by the date of issuance of a final rule. In the unlikely event that before a final rule becomes effective a person begins commercial manufacturing (including importing) or processing of the chemical substances for a use that is designated as a significant new use in that final rule, such a person would have to cease any such activity upon the effective date of the final rule. To resume their activities, these persons would have to first comply with all applicable SNUR notification requirements and wait until all TSCA prerequisites for the commencement of manufacture or processing have been satisfied. Issuance of a SNUR for a chemical substance does not signify that the chemical substance is listed on the TSCA Chemical Substance Inventory (TSCA Inventory). Guidance on how to determine if a chemical substance is on the TSCA Inventory is available on the internet at 
                    *https://www.epa.gov/​tsca-inventory.* C. Important Information About SNUN Submissions 1. SNUN Submissions SNUNs must be submitted on EPA Form No. 7710-25, generated using e-PMN software, and submitted to the Agency in accordance with the procedures set forth in 40 CFR 720.40 and 721.25. E-PMN software is available electronically at 
                    *https://www.epa.gov/​reviewing-new-chemicals-under-toxic-substances-control-act-tsca.* 2. Development and Submission of Information EPA recognizes that TSCA section 5 does not require development of any particular new information (
                    *e.g.,*
                     generating test data) before submission of a SNUN. There is an exception: If a person is required to submit information for a chemical substance pursuant to a rule, order or consent agreement under TSCA section 4, then TSCA section 5(b)(1)(A) requires such information to be submitted to EPA at the time of submission of the SNUN. In the absence of a rule, TSCA Order, or consent agreement under TSCA section 4 covering the chemical substance, persons are required only to submit information in their possession or control and to describe any other information known to or reasonably ascertainable by them (see 40 CFR 720.50). However, upon review of PMNs and SNUNs, the Agency has the authority to require appropriate testing. To assist with EPA's analysis of the SNUN, submitters are encouraged, but not required, to provide the potentially useful information as identified for the chemical substance in Unit III.C. of the proposed rule. EPA strongly encourages persons, before performing any testing, to consult with the Agency pertaining to protocol selection. Furthermore, pursuant to TSCA section 4(h), which pertains to reduction of testing in vertebrate animals, EPA encourages consultation with the Agency on the use of alternative test methods and strategies (also called New Approach Methodologies, or NAMs), if available, to generate the recommended test data. EPA encourages dialog with Agency representatives to help determine how best the submitter can meet both the data needs and the objective of TSCA section 4(h). For more information on alternative test methods and strategies to reduce vertebrate animal testing, visit 
                    *https://www.epa.gov/​assessing-and-managing-chemicals-under-tsca/​alternative-test-methods-and-strategies-reduce.* The potentially useful information described in Unit III. may not be the only means of providing information to evaluate the chemical substance associated with the significant new uses. However, submitting a SNUN without any test data may increase the likelihood that EPA will take action under TSCA section 5(e) or 5(f). EPA recommends that potential SNUN submitters contact EPA early enough so that they will be able to conduct the appropriate tests. SNUN submitters should be aware that EPA will be better able to evaluate SNUNs which provide detailed information about human exposure and environmental release that may result from the significant new use of the chemical substances. D. Public Comments on Proposed Rule and EPA Responses EPA received public comments on the proposed SNURs, and prepared a Response to Comment document that provides the Agency responses. The comments and the Response to Comment document are available in the docket. As described in the Response to Comment document, EPA is finalizing these SNURs with the following changes: For PMN P-21-56 (40 CFR 721.11868), EPA has reviewed the new test data submitted by the PMN submitter and no longer has the concern for skin sensitization based on the weight of available scientific evidence. The explanation is provided in the revised human health risk assessment, which has been added to the docket. EPA is modifying the significant new use terms included in the final SNUR. Two significant new uses, manufacturing the substance beyond 24 months and the requirement that the substance be classified as a skin sensitization risk on labels and the Safety Data Sheets, are not included in the final SNUR, and the company's 
                    ( print page 100364)
                    consent order is being modified accordingly.
                EPA inadvertently assigned the same CFR number to several proposed SNURs and has updated the CFR numbering for those SNURs. The proposed CFR numbering ranged from §§ 721.11860 through 721.11890, and the corrected CFR numbering ranges from §§ 721.11863 through 721.11893. III. Chemical Substances Subject to These SNURs A. What is the designated cutoff date for ongoing uses? EPA designates the date of publication of the proposed rule as the cutoff date for determining whether the new use is ongoing, 
                    *i.e.,*
                     June 11, 2024 (89 FR 49121 (FRL-11912-01-OCSPP)). This designation is explained further in Unit II.B. B. What information is provided for each chemical substance? In Unit III.C. of the proposed rule, EPA provided the following information for each chemical substance subject to these SNURs: PMN number (the CFR citation assigned in the regulatory text section of this document).
                Chemical name (generic name, if the specific name is claimed as CBI).
                Chemical Abstracts Service Registry Number (CASRN) or Accession Number (if assigned for non-confidential chemical identities).
                Basis for the SNUR (*e.g.,*
                     Effective date of and basis for the TSCA Order).
                Potentially useful information. The regulatory text section of this document specifies the activities designated as significant new uses. Certain new uses, including production volume limits and other uses designated, may be claimed as CBI. In addition, as discussed in Unit III.B. of the proposed rule, these SNURs include PMN substances that are subject to orders issued under TSCA section 5(e)(1)(A), as required by the determinations made under TSCA section 5(a)(3)(B). Those TSCA Orders require protective measures to limit exposures or otherwise mitigate the potential unreasonable risk. As such, the SNURs identify as significant new uses any manufacturing, processing, use, distribution in commerce, or disposal that does not conform to the restrictions imposed by the underlying TSCA Orders, consistent with TSCA section 5(f)(4). IV. Statutory and Executive Order Reviews Additional information about these statutes and Executive orders can be found at 
                    *https://www.epa.gov/​laws-regulations-and-executive-orders.* A. Executive Order 12866: Regulatory Planning and Review and Executive Order 14094: Modernizing Regulatory Review This action establishes SNURs for new chemical substances that were the subject of PMNs. The Office of Management and Budget (OMB) has exempted these types of actions from review under Executive Order 12866 (58 FR 51735, October 4, 1993), as amended by Executive Order 14094 (88 FR 21879, April 11, 2023). B. Paperwork Reduction Act (PRA) According to the PRA (44 U.S.C. 3501 
                    *et seq.*), an agency may not conduct or sponsor, and a person is not required to respond to a collection of information that requires OMB approval under PRA, unless it has been approved by OMB and displays a currently valid OMB control number. The OMB control numbers for EPA's regulations in title 40 of the CFR, after appearing in the 
                    **Federal Register**
                    , are listed in 40 CFR part 9, and included on the related collection instrument or form, if applicable. The information collection requirements related to SNURs have already been approved by OMB pursuant to PRA under OMB control number 2070-0038 (EPA ICR No. 1188). This action does not impose any burden requiring additional OMB approval. If an entity were to submit a SNUN to the Agency, the annual burden is estimated to average between 30 and 170 hours per submission. This burden estimate includes the time needed to review instructions, search existing data sources, gather and maintain the data needed, and complete, review, and submit the required SNUN. EPA always welcomes your feedback on the burden estimate. Send any comments about the accuracy of the burden estimate, and any suggested methods for improving the collection instruments or instruction or minimizing respondent burden, including through the use of automated collection techniques. C. Regulatory Flexibility Act (RFA) I certify that this action will not have a significant economic impact on a substantial number of small entities under the RFA (5 U.S.C. 601 
                    *et seq.*). The requirement to submit a SNUN applies to any person (including small or large entities) who intends to engage in any activity described in the final rule as a “significant new use.” Because these uses are “new,” based on all information currently available to EPA, EPA has concluded that no small or large entities presently engage in such activities. A SNUR requires that any person who intends to engage in such activity in the future must first notify EPA by submitting a SNUN. Although some small entities may decide to pursue a significant new use in the future, EPA cannot presently determine how many, if any, there may be. However, EPA's experience to date is that, in response to the promulgation of SNURs covering over 1,000 chemicals, the Agency receives only a small number of notices per year. For example, the number of SNUNs received was 7 in Federal fiscal year (FY) 2020, 13 in FY2021, 11 in FY2022, and 15 in FY2023, and only a fraction of these were from small businesses. In addition, the Agency currently offers relief to qualifying small businesses by reducing the SNUN submission fee from $37,000 to $6,480. This lower fee reduces the total reporting and recordkeeping cost of submitting a SNUN to about $14,500 per SNUN submission for qualifying small firms. Therefore, the potential economic impacts of complying with these SNURs are not expected to be significant or adversely impact a substantial number of small entities. In a SNUR that published in the 
                    **Federal Register**
                     of June 2, 1997 (62 FR 29684) (FRL-5597-1), the Agency presented its general determination that SNURs are not expected to have a significant economic impact on a substantial number of small entities, which was provided to the Chief Counsel for Advocacy of the Small Business Administration. D. Unfunded Mandates Reform Act (UMRA) This action does not contain an unfunded mandate of $100 million or more (in 1995 dollars) in any one year as described in UMRA, 2 U.S.C. 1531-1538, and does not significantly or uniquely affect small governments. Based on EPA's experience with proposing and finalizing SNURs, State, local, and Tribal governments have not been impacted by SNURs, and EPA does not have any reasons to believe that any State, local, or Tribal government will be impacted by these SNURs. In addition, the estimated costs of this action to the private sector do not exceed $183 million or more in any one year (the 1995 dollars are adjusted to 2023 dollars for inflation using the GDP implicit price deflator). The estimated costs for this action are discussed in Unit I.D
                    ( print page 100365) E. Executive Order 13132: Federalism This action will not have federalism implications as specified in Executive Order 13132 (64 FR 43255, August 10, 1999), because it is not expected to have a substantial direct effect on States, on the relationship between the National Government and the States, or on the distribution of power and responsibilities among the various levels of government. Accordingly, the requirements of Executive Order 13132 do not apply to this action. F. Executive Order 13175: Consultation and Coordination With Indian Tribal Governments This action will not have Tribal implications as specified in Executive Order 13175 (65 FR 67249, November 9, 2000), because it is not expected to have substantial direct effects on Indian Tribes, significantly or uniquely affect the communities of Indian Tribal governments and does not involve or impose any requirements that affect Indian Tribes. Accordingly, the requirements of Executive Order 13175 do not apply to this action. G. Executive Order 13045: Protection of Children From Environmental Health Risks and Safety Risks This action is not subject to Executive Order 13045 (62 FR 19885, April 23, 1997), because it does not concern an environmental health or safety risk. Since this action does not concern a human health risk, EPA's 2021 Policy on Children's Health also does not apply. Although the establishment of these SNURs do not address an existing children's environmental health concern because the chemical uses involved are not ongoing uses, SNURs require that persons notify EPA at least 90 days before commencing manufacture (defined by statute to include import) or processing of the identified chemical substances for an activity that is designated as a significant new use by the SNUR. This notification allows EPA to assess the intended uses to identify potential risks and take appropriate actions before the activities commence. H. Executive Order 13211: Actions Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use This action is not a “significant energy action” as defined in Executive Order 13211 (66 FR 28355, May 22, 2001), because it is not likely to have a significant adverse effect on the supply, distribution, or use of energy. I. National Technology Transfer and Advancement Act (NTTAA) This action does not involve any technical standards subject to NTTAA section 12(d) (15 U.S.C. 272 note). J. Executive Order 12898: Federal Actions To Address Environmental Justice in Minority Populations and Low-Income Populations and Executive Order 14096: Revitalizing Our Nation's Commitment to Environmental Justice for All EPA believes that this type of action does not concern human health or environmental conditions and therefore cannot be evaluated with respect to potentially disproportionate and adverse effects on communities with environmental justice concerns in accordance with Executive Orders 12898 (59 FR 7629, February 16, 1994) and 14096 (88 FR 25251, April 26, 2023). Although this action does not concern human health or environmental conditions, the notifications required by these SNURs allows EPA to assess the intended uses to identify potential disproportionate risks and take appropriate actions before the activities commence. K. Congressional Review Act (CRA) This action is subject to the CRA (5 U.S.C. 801 
                    *et seq.*), and EPA will submit a rule report to each House of the Congress and to the Comptroller General of the United States. This action is not a “major rule” as defined by 5 U.S.C. 804(2). List of Subjects 40 CFR Part 9 Environmental protection
Reporting and recordkeeping requirements 40 CFR Part 721 Environmental protection
Chemicals
Hazardous substances
Reporting and recordkeeping requirements
 Dated: December 6, 2024. Kevin DeBell, Acting Director, Office of Pollution Prevention and Toxics.
 Therefore, for the reasons stated in the preamble, 40 CFR chapter I is amended as follows: PART 9—OMB APPROVALS UNDER THE PAPERWORK REDUCTION ACT
 1.The authority citation for part 9 continues to read as follows: Authority:
                        7 U.S.C. 135 
                            *et seq.,*
                             136-136y; 15 U.S.C. 2001, 2003, 2005, 2006, 2601-2671; 21 U.S.C. 331j, 346a; 31 U.S.C. 9701; 33 U.S.C. 1251 
                            *et seq.,*
                             1311, 1313d, 1314, 1318, 1321, 1326, 1330, 1342, 1344, 1345 (d) and (e), 1361; E.O. 11735, 38 FR 21243, 3 CFR, 1971-1975 Comp. p. 973; 42 U.S.C. 241, 242b, 243, 246, 300f, 300g, 300g-1, 300g-2, 300g-3, 300g-4, 300g-5, 300g-6, 300j-1, 300j-2, 300j-3, 300j-4, 300j-9, 1857 
                            *et seq.,*
                             6901-6992k, 7401-7671q, 7542, 9601-9657, 11023, 11048. 2.Amend the table in § 9.1 by adding entries for §§ 721.11863 through 721.11893 in numerical order under the undesignated center heading “Significant New Uses of Chemical Substances” to read as follows: § 9.1
  
 40 CFR citation
OMB control No.*    *    *    *    ***Significant New Uses of Chemical Substances***    *    *    *    *721.11863
2070-0038721.11864
2070-0038721.11865
2070-0038721.11866
2070-0038721.11867
2070-0038721.11868
2070-0038721.11869
2070-0038721.11870
2070-0038721.11871
2070-0038721.11872
2070-0038721.11873
2070-0038721.11874
2070-0038721.11875
2070-0038721.11876
2070-0038721.11877
2070-0038721.11878
2070-0038721.11879
2070-0038721.11880
2070-0038721.11881
2070-0038721.11882
2070-0038721.11883
2070-0038721.11884
2070-0038721.11885
2070-0038721.11886
2070-0038721.11887
2070-0038721.11888
2070-0038721.11889
2070-0038721.11890
2070-0038721.11891
2070-0038721.11892
2070-0038721.11893
2070-0038*    *    *    *    *
 PART 721—SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES
 3.The authority citation for part 721 continues to read as follows: Authority:
                        15 U.S.C. 2604, 2607, and 2625(c). 4.Add §§ 721.11863 through 721.11893 to subpart E to read as follows: ( print page 100366)
                        
                        *****
                        721.11863
                        1,2-Ethanediamine, N-(1-methylethyl)-N-[2-[(1-methylethyl)amino]ethyl]-.
                        721.11864
                        Fatty acids, polymers with substituted carbomonocycles, dialkanolamine, alkyl substituted alkanediamine and halo-substituted heteromonocycle, formates (salts) (generic).
                        721.11865
                        Alkanesulfonic acid, 2-[(2-aminoethyl)heteroatom-substituted]-, sodium salt (1:1), polymer with .alpha.-[2,2-bis(hydroxymethyl)butyl]-.omega.-methoxypoly(oxy-1,2-ethanediyl) and 1,1′-methylenebis[4-isocyanatocyclohexane], acrylic acid-dipenthaerythritol reaction products- and polypropylene glycol ether with pentaerythritol (4:1) triacrylate-blocked (generic).
                        721.11866
                        Alkanoic acid, hydroxy-(hydroxyalkyl)-alkyl-, polymer with .alpha.-[(hydroxyalkyl)alkyl]-.omega.-alkoxypoly(oxy-alkanediyl), (haloalkyl)oxiane polymer (alkylalkylidene)bis[hydroxy-carbomonocycle] alkenoate and isocyanate-alkyl-carbomonocycle, hydroxyalkyl acrylate-blocked (generic).
                        721.11867
                        1,4-Benzenedicarboxylic acid, bis[2-(2-butoxyethoxy)ethyl] ester (9CI).
                        721.11868
                        Isocyanic acid, polyalkylenepolyarylene ester, polymer with alkyl-hydroxyalkyl-alkanediol, alkoxyalcohol and alkoxylalkoxyalcohol-blocked (generic).
                        721.11869
                        Substituted alkanoic acid, compound with aminoalkylalkyl-aminoalkylalkoxy-polyoxyalkylalkanediyl, polymer with haloalkyl-epoxide and alkylalkylidene-cycloarylalcohol (generic).
                        721.11870
                        Bisphenol A epichlorohydrin polymer with alkylpolyalkene-polyarylene-hydroxypolyoxyalkyldiyl reaction products with alkylalkylidenealkylalkylidene-aminoalkyl-alkanepolyamine and alkylaminoalkanol (generic).
                        721.11871
                        Sulfur based acid, compds. with modified bisphenol A-epichlorohydrin-polyalkylene polyol ether with bisphenol A polymer-N-dialkylalkylidene-N- (dialkylalklyidene)aminoalkyl-alkanepolyamine-alkylaminoalkanol reaction products (generic).
                        721.11872
                        1,2-Alkanediol, 3-aryloxy, mono phosphate ester (generic).
                        721.11873
                        Metalloxanes, alkyl, alkyl group-terminated, reaction products with dihalo-dialkylalkylaryl-alkyl-polycyclic-ylidene(dialkylsilylene)-dialkylalkylaryl-alkylalkyl-polycyclic-ylidene, metal oxide and nonmetallic oxide (generic).
                        721.11874
                        Alkenoic acid, reaction products with pentaerythritol, polymers with diisocyanatoalkane and heteromonocyle homopolymer esters with alkanoic acid-pentaerythritol reaction products (generic).
                        721.11875
                        Carbopolycycle octa-alkene, halo (generic).
                        721.11876
                        2-Propenoic acid, (polyhydro-1,3-dioxo-2H-isoindol-2-yl)alkyl ester (generic).
                        721.11877
                        Heteromonocycle, polymer, [2-[(1-oxo-2-propen-1-yl)oxy]alkyl]ester (generic).
                        721.11878
                        Hydrocarbons linear and branched, light alkylate (generic).
                        721.11879
                        Hydrocarbons linear and branched, light catalytic cracked (generic).
                        721.11880
                        Hydrocarbons linear and branched, heavy catalytic cracked (generic).
                        721.11881
                        Hydrocarbons linear and branched, light hydrocracked (generic).
                        721.11882
                        Hydrocarbons linear and branched, isomerization (generic).
                        721.11883
                        Hydrocarbons linear and branched, heavy catalytic reformed (generic).
                        721.11884
                        Hydrocarbons linear and branched, hydrotreated light (generic).
                        721.11885
                        Hydrocarbons linear and branched, hydrotreated light paraffinic (generic).
                        721.11886
                        Hydrocarbons linear and branched, light catalytic cracked (generic).
                        721.11887
                        Hydrocarbons linear and branched, heavy hydrocracked (generic).
                        721.11888
                        Hydrocarbons linear and branched, heavy catalytic cracked (generic).
                        721.11889
                        Hydrocarbons linear and branched, heavy hydrocracked (generic).
                        721.11890
                        Hydrocarbons linear and branched, light hydrocracked (generic).
                        721.11891
                        Imidazole-carboxylic acid, substituted (generic).
                        721.11892
                        Multi-walled carbon nanotubes (generic).
                        721.11893
                        Multi-walled carbon nanotubes (generic).
 
 § 721.11863
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified as 1,2-ethanediamine, N-(1-methylethyl)-N-[2-[(1-methylethyl) amino]ethyl]- (PMN P-18-398; CASRN 10507-06-9) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity; specific target organ toxicity; reproductive toxicity; skin corrosion; serious eye damage; skin sensitization. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(k). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11864
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as fatty acids, polymers with substituted carbomonocycles, dialkanolamine, alkyl substituted alkanediamine and halo-substituted heteromonocycle, formates (salts) (PMN P-19-49) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes 
                            ( print page 100367)
                            of § 721.63(b), the concentration is set at 1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1), (3), and (5). For purposes of § 721.72(e), the concentration is set at 1%. For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; reproductive toxicity; specific organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture or process the substance in any manner that generates a vapor, mist, or aerosol. It is a significant new use to use the substance in any manner that generates a vapor, mist, or aerosol that results in inhalation to industrial or commercial workers. It is a significant new use to manufacture the substance to contain the confidential residual identified in the TSCA Order for this substance at greater than 0.1%. (iv) 
                            *Release to Water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=114. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11865
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as alkanesulfonic acid, 2-[(2-aminoethyl)heteroatom-substituted]-, sodium salt (1:1), polymer with .alpha.-[2,2-bis(hydroxymethyl)butyl]-.omega.-methoxypoly(oxy-1,2-ethanediyl) and 1,1′-methylenebis[4-isocyanatocyclohexane], acrylic acid-dipenthaerythritol reaction products- and polypropylene glycol ether with pentaerythritol (4:1) triacrylate-blocked (PMN P-19-160) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1) and (5). For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; serious eye damage; skin sensitization; respiratory sensitization; reproductive toxicity; specific organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (iv) 
                            *Release to Water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=302. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11866
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance generically identified as alkanoic acid, hydroxy-(hydroxyalkyl)-alkyl-, polymer with .alpha.-[(hydroxyalkyl)alkyl]-.omega.-alkoxypoly(oxy-alkanediyl), (haloalkyl)oxiane polymer (alkylalkylidene)bis[hydroxy-carbomonocycle] alkenoate and isocyanate-alkyl-carbomonocycle, hydroxyalkyl acrylate-blocked (PMN P-20-101) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely cured. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity; skin irritation; eye irritation; respiratory sensitization; skin sensitization; reproductive toxicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to manufacture or process the substance with greater than 20% (by weight) oligomer content below 1,000 daltons (
                            *i.e.,*
                             low molecular weight species). It is a significant new use to use the substance in a manual spray application. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The 
                            ( print page 100368)
                            provisions of § 721.185 apply to this section.
 § 721.11867
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified as 1,4-benzenedicarboxylic acid, bis[2-(2-butoxyethoxy)ethyl] ester (9CI) (PMN P-20-182; CASRN 90430-63-0) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1,000. (A) As an alternative to the respirator requirements in paragraph (a)(2)(i) of this section, a manufacturer or processor may choose to follow the new chemical exposure limit (NCEL) provision listed in the TSCA section 5(e) Order for this substance. The NCEL is 0.01 mg/m3
                             as an 8-hour time weighted average. Persons who wish to pursue NCELs as an alternative to § 721.63 respirator requirements may request to do so under § 721.30. Persons whose § 721.30 requests to use the NCELs approach are approved by EPA will be required to follow NCELs provisions comparable to those contained in the corresponding TSCA section 5(e) Order. (B) [Reserved] (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: skin sensitization; reproductive toxicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N=4. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (h) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11868
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as isocyanic acid, polyalkylenepolyarylene ester, polymer with alkyl-hydroxyalkyl-alkanediol, alkoxyalcohol and alkoxylalkoxyalcohol-blocked (PMN P-21-56) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50 or 1,000 if spray applied. For purposes of § 721.63(b), the concentration is set at 1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1) and (5). For purposes of § 721.72(e), the concentration is set at 1%. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11869
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as substituted alkanoic acid, compound with aminoalkylalkyl-aminoalkylalkoxy-polyoxyalkylalkanediyl, polymer with haloalkyl-epoxide and alkylalkylidene-cycloarylalcohol (PMN P-21-58) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1), (3), and (5). For purposes of § 721.72(e), the concentration is set at 1%. For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used.
                            ( print page 100369) (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 50. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11870
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as bisphenol A epichlorohydrin polymer with alkylpolyalkene-polyarylene-hydroxypolyoxyalkyldiyl reaction products with alkylalkylidenealkylalkylidene-aminoalkyl-alkanepolyamine and alkylaminoalkanol (PMN P-21-60) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1), (3), and (5). For purposes of § 721.72(e), the concentration is set at 0.1%. For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; carcinogenicity; reproductive toxicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.118671
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as sulfur based acid, compds. with modified bisphenol A-epichlorohydrin-polyalkylene polyol ether with bisphenol A polymer-N-dialkylalkylidene-N-(dialkylalklyidene)aminoalkyl-alkanepolyamine-alkylaminoalkanol reaction products (PMN P-21-61) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1), (3), and (5). For purposes of § 721.72(e), the concentration is set at 0.1%. For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; carcinogenicity; reproductive toxicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure. (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 11. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11872
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as 1,2-alkanediol, 3-aryloxy, mono phosphate ester (PMN P-21-66) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely destroyed. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general 
                            ( print page 100370)
                            and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 1.0%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1), (3), and (5). For the purposes of § 721.72(e), the concentration is set at 1.0%. For purposes of § 721.72(g)(1), this substance may cause: acute toxicity; skin corrosion; skin irritation; serious eye damage; eye irritation; reproductive toxicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation exposure or that results in fugitive air emissions. It is a significant new use to use the substance other than as an epoxy curative. (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11873
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as metalloxanes, alkyl, alkyl group-terminated, reaction products with dihalo-dialkylalkylaryl-alkyl-polycyclic-ylidene(dialkylsilylene)-dialkylalkylaryl-alkylalkyl-polycyclic-ylidene, metal oxide and nonmetallic oxide (PMN P-21-68) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1) and (5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity; skin corrosion; skin irritation; serious eye damage; eye irritation; respiratory sensitization; skin sensitization; germ cell mutagenicity; reproductive toxicity; specific target organ toxicity. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(a) through (c). It is a significant new use to manufacture, process, or use the substance in any manner that results in inhalation or dermal exposure. (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 50. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i), and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11874
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as alkenoic acid, reaction products with pentaerythritol, polymers with diisocyanatoalkane and heteromonocyle homopolymer esters with alkanoic acid-pentaerythritol reaction products (PMN P-21-83) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1,000. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3) and (5). For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; respiratory sensitization; skin sensitization; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 1. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11875
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as carbopolycycle octa-alkene, halo (PMN P-21-84) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
                            ( print page 100371) (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity; skin corrosion; serious eye damage; skin sensitization; genetic toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 7. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (h) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11876
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as 2-propenoic acid, (polyhydro-1,3-dioxo-2H-isoindol-2-yl)alkyl ester (PMN P-21-92) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the PMN substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 1.0%. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 10. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (f) and (g)(1) and (3). For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; specific target organ toxicity; reproductive toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. For purposes of § 721.72(e), the concentration is set at 1.0%. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). It is a significant new use to use the substance at a concentration of greater than 40% in formulation when inhalation exposure is expected. (iv) 
                            *Disposal.*
                             It is a significant new use to dispose of the substance or waste streams containing the substance other than by incineration or RCRA subtitle C landfill. (v) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11877
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as heteromonocycle, polymer, [2-[(1-oxo-2-propen-1-yl)oxy]alkyl]ester (PMN P-21-102) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 10. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: skin irritation; eye irritation; specific target organ toxicity; developmental toxicity; skin sensitization. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(o). (iv) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(4), (b)(4), and (c)(4), where N = 337. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) and (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11878
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, light alkylate (PMN P-21- 
                            ( print page 100372)
                            109) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11879
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, light catalytic cracked (PMN P-21-110) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11880
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, heavy catalytic cracked (PMN P-21-111) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11881
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, light hydrocracked (PMN P-21-112) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent 
                            ( print page 100373)
                            exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through(i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11882
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, isomerization (PMN P-21-113) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11883
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, heavy catalytic reformed (PMN P-21-114) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11884
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, hydrotreated light (PMN P-21-116) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in 
                            ( print page 100374)
                            § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11885
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, hydrotreated light paraffinic (PMN P-21-117) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11886
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance generically identified as hydrocarbons linear and branched, light catalytic cracked (PMN P-21-118) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11887
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, heavy hydrocracked (PMN P-21-119) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11888
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, heavy catalytic cracked (PMN P-21-121) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to 
                            ( print page 100375)
                            cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11889
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, heavy hydrocracked (PMN P-21-122) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11890
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as hydrocarbons linear and branched, light hydrocracked (PMN P-21-123) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into a fuel, fuel additive, fuel blending stock, or used as a refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting). (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3), (b), and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(b), the concentration is set at 0.1%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a). (iii) 
                            *Industrial, commercial, and consumer activities.*
                             It is a significant new use to manufacture, process, or use the substance other than for processing and use as a fuel, fuel additive, fuel blending stock, or refinery feedstock (including, but not limited to cracking, coking, hydroprocessing, distillation, or deasphalting) subject to 40 CFR part 79 or 1090. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (i) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11891
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as imidazole-carboxylic acid, substituted (P-21-197) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been incorporated into an article. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 50. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3) and (5). For purposes of § 721.72(g)(1), this substance may cause: acute toxicity; skin corrosion; eye irritation; serious eye damage; skin sensitization; 
                            ( print page 100376)
                            reproductive toxicity; specific target organ toxicity. For purposes of § 721.72(g)(3) this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(f). It is a significant new use to process or use the substance other than in an enclosed process, except that sampling and equipment cleaning operations need not occur in an enclosed process. (iv) 
                            *Disposal.*
                             It is a significant new use to dispose of the substance or waste streams containing the substance other than by incineration with 99.9% efficiency. (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (j) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11892
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as multi-walled carbon nanotubes (PMN P-21-216) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured), entrained in a polymer, or incorporated into an article. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1,000 if the capture and reduction rate is at least 99.5% but not 99.975% or greater, or at least 50 if the capture and reduction rate is at least 99.975%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: eye irritation; skin irritation; respiratory sensitization; skin sensitization; genetic toxicity; reproductive toxicity; carcinogenicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(f). It is a significant new use to manufacture the substance to contain the confidential impurity listed in the Order at greater than 1% (by weight). It is a significant new use to process or use the substance other than for the confidential use allowed in the Order. It is a significant new use to process or use the substance other than in application methods that do not generate a vapor, mist, dust, or aerosol, unless such application method occurs in an enclosed process. (iv) 
                            *Disposal.*
                             Requirements as specified in § 721.85 (a)(1) and (2), (b)(1) and (2), and (c)(1) and (2). It is a significant new use to release the substance directly, whether by point (stack) or non-point (fugitive) sources, to air. (v) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1). (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.
 § 721.11893
  (a) 
                            *Chemical substance and significant new uses subject to reporting.*
                             (1) The chemical substance identified generically as multi-walled carbon nanotubes (PMN P-21-217) is subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section. The requirements of this section do not apply to quantities of the substance after they have been completely reacted (cured), entrained in a polymer, or incorporated into an article. (2) The significant new uses are: (i) 
                            *Protection in the workplace.*
                             Requirements as specified in § 721.63(a)(1) and (3) through (5) and (c). When determining which persons are reasonably likely to be exposed as required for § 721.63(a)(1) and (4), engineering control measures (
                            *e.g.,*
                             enclosure or confinement of the operation, general and local ventilation) or administrative control measures (
                            *e.g.,*
                             workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible. For purposes of § 721.63(a)(5), respirators must provide a National Institute for Occupational Safety and Health (NIOSH) assigned protection factor (APF) of at least 1,000 if the capture and reduction rate is at least 99.5% but not 99.975% or greater or of at least 50 if the capture and reduction rate is at least 99.975%. (ii) 
                            *Hazard communication.*
                             Requirements as specified in § 721.72(a) through (d), (f), and (g)(1), (3), and (5). For purposes of § 721.72(g)(1), this substance may cause: eye irritation; skin irritation; respiratory sensitization; skin sensitization; genetic toxicity; reproductive toxicity; carcinogenicity; specific target organ toxicity. For purposes of § 721.72(g)(3), this substance may be: toxic to aquatic life. Alternative hazard and warning statements that meet the criteria of the Globally Harmonized System and OSHA Hazard Communication Standard may be used. (iii) 
                            *Industrial, commercial, and consumer activities.*
                             Requirements as specified in § 721.80(f). It is a significant new use to manufacture the substance to contain the confidential impurity listed in the Order at greater than 1% (by weight). It is a significant new use to process or use the substance other than for the confidential use allowed in the Order. It is a significant new use to process or use the substance other than in application methods that do not generate a vapor, mist, dust, or aerosol, unless such application method occurs in an enclosed process. (iv) 
                            *Disposal.*
                             Requirements as specified in § 721.85 (a)(1) and (2), (b)(1) and (2), and (c)(1) and (2). It is a significant new use to release the substance directly, either by point (stack) or non-point (fugitive) sources, to air. (v) 
                            *Release to water.*
                             Requirements as specified in § 721.90(a)(1), (b)(1), and (c)(1).
                            ( print page 100377) (b) 
                            *Specific requirements.*
                             The provisions of subpart A of this part apply to this section except as modified by this paragraph (b). (1) 
                            *Recordkeeping.*
                             Recordkeeping requirements as specified in § 721.125(a) through (k) are applicable to manufacturers, importers, and processors of this substance. (2) 
                            *Limitation or revocation of certain notification requirements.*
                             The provisions of § 721.185 apply to this section.


[FR Doc. 2024-29276 Filed 12-11-24; 8:45 am] BILLING CODE 6560-50-P